Motif ID: GUGCAAA

Z-value: 1.695


Mature miRNA associated with seed GUGCAAA:

NamemiRBase Accession
hsa-miR-19a MIMAT0000073
hsa-miR-19b MIMAT0000074



Activity profile for motif GUGCAAA.

activity profile for motif GUGCAAA


Sorted Z-values histogram for motif GUGCAAA

Sorted Z-values for motif GUGCAAA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUGCAAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_136834887 35.522 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr6_+_121756744 28.317 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr14_-_60097531 26.093 NM_206852
RTN1
reticulon 1
chr9_-_138987096 25.487 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr14_-_60337350 24.810 NM_021136
RTN1
reticulon 1
chr4_+_41614911 22.124 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_51701943 21.725 NM_014372
RNF11
ring finger protein 11
chr5_-_73937248 21.555 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr12_+_79439432 21.253 NM_001135806
SYT1
synaptotagmin I
chr15_-_73925658 21.019 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr4_+_41362750 20.465 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr12_+_79257772 20.437 NM_001135805
SYT1
synaptotagmin I
chr14_+_90863302 20.244 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr2_+_20646831 20.132 NM_004040
RHOB
ras homolog gene family, member B
chr7_+_134464161 20.120 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr12_+_79258448 19.790 NM_005639
SYT1
synaptotagmin I
chr10_-_118765087 19.775 NM_001127211
NM_018330
KIAA1598

KIAA1598

chr11_-_12030128 19.731 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_160175114 19.183 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr22_-_36236421 18.970 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr11_-_12030882 18.774 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030622 18.148 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr6_-_134498973 17.732 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_69455837 17.629 NM_053056
CCND1
cyclin D1
chr7_-_95064213 17.627 NM_000305
NM_001018161
PON2

paraoxonase 2

chr17_-_1090562 17.118 NM_001159746
ABR
active BCR-related gene
chr20_+_19867075 16.990 NM_001242581
RIN2
Ras and Rab interactor 2
chr16_+_14164879 16.635 NM_014048
MKL2
MKL/myocardin-like 2
chr2_+_9346876 16.502 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chrX_+_135067573 16.442 NM_001177651
NM_001042537
NM_006359
SLC9A6


solute carrier family 9 (sodium/hydrogen exchanger), member 6


chr8_-_12973752 16.257 NM_001164271
DLC1
deleted in liver cancer 1
chr15_-_52861177 16.206 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr15_+_99645152 15.811 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr1_+_236557643 15.791 NM_145861
EDARADD
EDAR-associated death domain
chr20_-_36156282 15.663 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr6_-_134496006 15.598 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr20_-_36152952 15.591 NM_001167823
BLCAP
bladder cancer associated protein
chr12_+_78225068 15.284 NM_014903
NAV3
neuron navigator 3
chr6_-_16761600 15.236 NM_000332
NM_001128164
ATXN1

ataxin 1

chr6_-_134639195 15.140 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr20_+_19870209 15.036 NM_018993
RIN2
Ras and Rab interactor 2
chr17_-_1012257 15.005 NM_001092
ABR
active BCR-related gene
chr20_-_36156082 14.994 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr22_-_36424397 14.544 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr6_-_134497069 14.186 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr14_-_69446038 14.129 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr8_-_103137134 13.881 NM_001040630
NCALD
neurocalcin delta
chr1_-_149889362 13.451 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr8_+_132916339 13.411 NM_015137
EFR3A
EFR3 homolog A (S. cerevisiae)
chr5_+_71403040 13.384 NM_005909
MAP1B
microtubule-associated protein 1B
chr1_+_15272414 13.379 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr13_-_30424795 13.275 NM_007106
UBL3
ubiquitin-like 3
chr7_-_45960738 13.223 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr6_-_132272311 13.044 NM_001901
CTGF
connective tissue growth factor
chr8_-_12990731 12.550 NM_006094
DLC1
deleted in liver cancer 1
chr10_-_79686279 12.358 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr7_+_872137 12.345 NM_001130965
SUN1
Sad1 and UNC84 domain containing 1
chr11_-_117166247 12.262 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr16_+_3070310 11.932 NM_016639
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chrX_-_10588458 11.906 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr9_-_14398981 11.811 NM_001190738
NFIB
nuclear factor I/B
chr7_+_134576150 11.635 NM_033139
NM_033140
CALD1

caldesmon 1

chr15_-_34394016 11.630 NM_020154
C15orf24
chromosome 15 open reading frame 24
chrX_-_10851808 11.613 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr4_+_166248816 11.588 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr8_+_20054703 11.546 NM_001693
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr17_-_1083008 11.452 NM_021962
ABR
active BCR-related gene
chr8_-_102803438 11.248 NM_032041
NCALD
neurocalcin delta
chr9_-_79520878 11.235 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_38869346 10.906 NM_138389
FAM114A1
family with sequence similarity 114, member A1
chr1_-_95007139 10.639 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr17_+_57697036 10.607 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr17_-_57184174 10.584 NM_001005207
NM_015294
TRIM37

tripartite motif containing 37

chr12_+_56367696 10.491 NM_001252036
NM_001252037
NM_002868
RAB5B


RAB5B, member RAS oncogene family


chr15_-_49338496 10.408 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr20_-_48330417 10.338 NM_004776
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr8_-_110657745 10.280 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr8_-_103136486 10.279 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr1_+_15256295 10.177 NM_001018001
KAZN
kazrin, periplakin interacting protein
chr8_-_110704019 9.990 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr7_+_45614081 9.941 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr8_-_110657025 9.885 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr1_+_39547088 9.855 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr8_-_110655418 9.834 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr16_-_66785511 9.684 NM_006141
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr6_-_167275657 9.680 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_10270680 9.584 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr3_-_66550844 9.504 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chrX_-_10645726 9.462 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_180404 9.456 NM_006624
NM_001202465
NM_001202466
NM_212479
ZMYND11



zinc finger, MYND-type containing 11



chr12_-_106533810 9.454 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr2_-_86565205 9.351 NM_001164730
REEP1
receptor accessory protein 1
chrX_-_10544852 9.228 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_28966419 9.157 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr2_-_86094792 9.142 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_-_14314036 9.125 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr8_-_110661007 9.067 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_+_155829259 9.060 NM_152280
SYT11
synaptotagmin XI
chr10_+_6186758 8.998 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr14_-_54955714 8.947 NM_004124
GMFB
glia maturation factor, beta
chr5_-_78809658 8.925 NM_004272
HOMER1
homer homolog 1 (Drosophila)
chr3_+_50712671 8.889 NM_004947
DOCK3
dedicator of cytokinesis 3
chr11_-_46722115 8.880 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr2_-_1748285 8.867 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr1_-_153958688 8.817 NM_002870
RAB13
RAB13, member RAS oncogene family
chr2_+_189156395 8.769 NM_001252668
NM_001252669
NM_016315
GULP1


GULP, engulfment adaptor PTB domain containing 1


chr11_-_17191287 8.670 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr8_-_110693233 8.637 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr1_+_236558715 8.562 NM_080738
EDARADD
EDAR-associated death domain
chr11_-_117186918 8.453 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chrX_+_152954965 8.392 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_-_85555343 8.214 NM_001206840
NM_001206841
NM_001206844
NM_006464
TGOLN2



trans-golgi network protein 2



chr1_+_84609941 8.200 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_-_34675366 8.185 NM_031442
TMEM47
transmembrane protein 47
chr5_+_140345746 8.127 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr15_+_40509628 8.033 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr5_+_140186658 8.025 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr17_-_80606095 8.017 NM_019613
WDR45L
WDR45-like
chr5_+_140220811 7.974 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr1_+_15250578 7.968 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr15_+_52311408 7.952 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr6_-_167040700 7.823 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr18_-_812268 7.809 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr2_-_2334887 7.785 NM_015025
MYT1L
myelin transcription factor 1-like
chr2_+_223725675 7.760 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr17_-_73851377 7.694 NM_012478
WBP2
WW domain binding protein 2
chr8_-_17555158 7.682 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr2_-_169103886 7.658 NM_013233
STK39
serine threonine kinase 39
chr13_-_107187312 7.650 NM_004093
EFNB2
ephrin-B2
chr2_-_86116016 7.611 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_160085519 7.537 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr7_-_111846384 7.471 NM_014705
DOCK4
dedicator of cytokinesis 4
chr13_-_36944289 7.399 NM_001142294
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr14_-_95623665 7.283 NM_177438
DICER1
dicer 1, ribonuclease type III
chr20_+_1246959 7.271 NM_014723
SNPH
syntaphilin
chr3_+_100211408 7.237 NM_018004
TMEM45A
transmembrane protein 45A
chr8_+_104310660 7.166 NM_001164615
FZD6
frizzled family receptor 6
chr4_-_56412968 7.165 NM_004898
CLOCK
clock homolog (mouse)
chr18_+_8717368 7.112 NM_015210
CCDC165
coiled-coil domain containing 165
chr1_+_244214552 7.108 NM_205768
ZNF238
zinc finger protein 238
chr12_-_120315074 7.071 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr11_-_45687135 7.033 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr5_+_140213968 7.031 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr1_-_93426998 7.025 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr9_+_131873592 7.018 NM_178000
NM_178001
NM_178003
PPP2R4


protein phosphatase 2A activator, regulatory subunit 4


chr18_+_3412071 7.014 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr1_+_84630014 7.013 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr5_+_95997871 6.893 NM_001042440
CAST
calpastatin
chrX_+_152953751 6.869 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chrX_-_47479229 6.868 NM_006950
NM_133499
SYN1

synapsin I

chr8_+_104311058 6.800 NM_001164616
NM_003506
FZD6

frizzled family receptor 6

chr3_+_171757413 6.795 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr9_+_131873752 6.756 NM_001193397
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr5_+_95997723 6.696 NM_001190442
CAST
calpastatin
chr7_-_50861114 6.582 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr10_+_181410 6.560 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr2_+_173292306 6.553 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr2_-_86564632 6.547 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr11_+_12132063 6.546 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr5_+_140254930 6.540 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr1_+_28099682 6.506 NM_177424
STX12
syntaxin 12
chr14_-_95599794 6.443 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr13_+_35516390 6.408 NM_015678
NBEA
neurobeachin
chr10_-_73611050 6.385 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr2_+_8822112 6.383 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr9_-_93405066 6.382 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr14_+_32546445 6.349 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr15_+_39873276 6.343 NM_003246
THBS1
thrombospondin 1
chr14_+_65007163 6.272 NM_021979
HSPA2
heat shock 70kDa protein 2
chr22_-_21088954 6.236 NM_002650
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr18_+_3453771 6.226 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr11_-_65667860 6.205 NM_005438
FOSL1
FOS-like antigen 1
chr1_+_236305831 6.171 NM_003272
GPR137B
G protein-coupled receptor 137B
chr1_-_201438150 6.164 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr10_-_75173807 6.160 NM_001156
NM_004034
ANXA7

annexin A7

chr9_-_10612722 6.142 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr5_+_140247767 6.100 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr3_+_49506079 6.052 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr13_-_36920603 6.041 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr7_-_50800018 6.022 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chrX_+_118714297 5.987 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A
chr22_-_39548448 5.985 NM_175709
CBX7
chromobox homolog 7
chr8_-_67525426 5.984 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr8_-_17658385 5.946 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr1_-_185286460 5.781 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr3_-_178789597 5.727 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr20_-_43150686 5.696 NM_006811
NM_198941
SERINC3

serine incorporator 3

chr13_-_36920777 5.681 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_-_117210301 5.648 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr15_+_62939509 5.629 NM_015059
TLN2
talin 2
chr3_+_49591897 5.627 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr10_+_63661012 5.623 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_84647342 5.595 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_198125890 5.502 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr18_+_3447607 5.437 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chrX_+_128674181 5.392 NM_000276
NM_001587
OCRL

oculocerebrorenal syndrome of Lowe

chr5_-_140070953 5.361 NM_002109
HARS
histidyl-tRNA synthetase
chr3_+_187943192 5.350 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_-_5890266 5.306 NM_001313
CRMP1
collapsin response mediator protein 1
chr1_-_51984994 5.297 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 4.31e-09 GO:0009987 cellular process
1.64 6.47e-08 GO:0023052 signaling
1.38 3.57e-07 GO:0050794 regulation of cellular process
1.57 5.30e-07 GO:0051716 cellular response to stimulus
1.63 1.30e-06 GO:0007165 signal transduction
2.02 5.83e-06 GO:0007399 nervous system development
1.34 6.71e-06 GO:0050789 regulation of biological process
1.31 1.17e-05 GO:0065007 biological regulation
2.56 4.60e-05 GO:0007167 enzyme linked receptor protein signaling pathway
2.00 5.99e-05 GO:0035556 intracellular signal transduction
2.75 7.37e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.84 3.30e-04 GO:0023051 regulation of signaling
2.22 3.72e-04 GO:0048699 generation of neurons
2.89 5.52e-04 GO:0007264 small GTPase mediated signal transduction
1.57 7.81e-04 GO:0048731 system development
2.13 8.60e-04 GO:0022008 neurogenesis
2.55 2.24e-03 GO:0019226 transmission of nerve impulse
2.55 2.24e-03 GO:0035637 multicellular organismal signaling
1.31 3.69e-03 GO:0050896 response to stimulus
2.60 4.98e-03 GO:0007268 synaptic transmission
1.64 6.10e-03 GO:0030154 cell differentiation
2.15 6.37e-03 GO:0016192 vesicle-mediated transport
1.61 9.73e-03 GO:0048869 cellular developmental process
1.48 9.82e-03 GO:0048856 anatomical structure development
1.77 1.10e-02 GO:0009966 regulation of signal transduction
3.11 1.29e-02 GO:0050767 regulation of neurogenesis
2.80 1.60e-02 GO:0060284 regulation of cell development
5.04 1.70e-02 GO:0050769 positive regulation of neurogenesis
1.78 1.94e-02 GO:0033036 macromolecule localization
1.43 2.02e-02 GO:0051179 localization
2.60 2.26e-02 GO:0051056 regulation of small GTPase mediated signal transduction
5.10 3.80e-02 GO:0031346 positive regulation of cell projection organization
4.24 4.06e-02 GO:0010720 positive regulation of cell development
3.05 4.68e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.39 4.82e-02 GO:0032502 developmental process
1.76 4.92e-02 GO:0010033 response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 2.98e-11 GO:0005737 cytoplasm
1.27 1.10e-04 GO:0016020 membrane
2.13 2.90e-04 GO:0005626 insoluble fraction
1.77 3.69e-04 GO:0012505 endomembrane system
1.93 5.50e-04 GO:0000267 cell fraction
1.15 5.82e-04 GO:0005622 intracellular
2.10 6.75e-04 GO:0005624 membrane fraction
4.00 7.57e-04 GO:0005769 early endosome
2.15 8.15e-04 GO:0031988 membrane-bounded vesicle
1.08 9.50e-04 GO:0044464 cell part
1.08 9.66e-04 GO:0005623 cell
2.09 9.73e-04 GO:0031982 vesicle
1.30 1.01e-03 GO:0044444 cytoplasmic part
2.49 1.37e-03 GO:0005768 endosome
2.94 1.96e-03 GO:0012506 vesicle membrane
1.15 2.27e-03 GO:0044424 intracellular part
2.06 2.31e-03 GO:0031410 cytoplasmic vesicle
2.09 2.87e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.21 3.36e-03 GO:0030054 cell junction
1.58 4.20e-03 GO:0005829 cytosol
1.89 4.20e-03 GO:0005794 Golgi apparatus
2.49 4.26e-03 GO:0045202 synapse
2.77 1.22e-02 GO:0030659 cytoplasmic vesicle membrane
2.81 1.59e-02 GO:0042598 vesicular fraction
1.34 1.87e-02 GO:0071944 cell periphery
1.51 1.95e-02 GO:0044459 plasma membrane part
2.53 2.04e-02 GO:0044433 cytoplasmic vesicle part
1.34 2.10e-02 GO:0005886 plasma membrane
2.06 2.81e-02 GO:0044431 Golgi apparatus part
2.75 3.20e-02 GO:0005792 microsome
4.20 3.68e-02 GO:0030665 clathrin coated vesicle membrane
2.90 4.06e-02 GO:0030135 coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.43 6.31e-12 GO:0005515 protein binding
1.17 6.67e-06 GO:0005488 binding
1.78 1.90e-05 GO:0017076 purine nucleotide binding
1.76 5.77e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.75 5.96e-05 GO:0032553 ribonucleotide binding
1.75 5.96e-05 GO:0032555 purine ribonucleotide binding
2.66 1.42e-04 GO:0030695 GTPase regulator activity
2.59 2.59e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.77 5.92e-04 GO:0030554 adenyl nucleotide binding
1.59 9.55e-04 GO:0000166 nucleotide binding
1.75 9.56e-04 GO:0032559 adenyl ribonucleotide binding
1.75 1.09e-03 GO:0005524 ATP binding
2.88 2.18e-03 GO:0005083 small GTPase regulator activity
3.26 4.19e-03 GO:0005543 phospholipid binding
2.31 1.90e-02 GO:0008289 lipid binding
3.90 2.16e-02 GO:0017124 SH3 domain binding