Motif ID: HAND1,2.p2

Z-value: 2.383


Transcription factors associated with HAND1,2.p2:

Gene SymbolEntrez IDGene Name
HAND1 9421 heart and neural crest derivatives expressed 1
HAND2 9464 heart and neural crest derivatives expressed 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HAND1chr5_-_1538577820.718.1e-35Click!
HAND2chr4_-_1744513560.544.5e-18Click!


Activity profile for motif HAND1,2.p2.

activity profile for motif HAND1,2.p2


Sorted Z-values histogram for motif HAND1,2.p2

Sorted Z-values for motif HAND1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792370 66.726 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr19_-_37701385 54.330 NM_152279
ZNF585B
zinc finger protein 585B
chr5_-_149792276 52.404 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_-_107179043 52.365 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_22723972 49.381


chr22_+_23213671 47.061 IGLV4-3
immunoglobulin lambda variable 4-3
chr19_-_9695166 43.532 NM_001008727
ZNF121
zinc finger protein 121
chr1_-_155904201 43.308 KIAA0907
KIAA0907
chrX_+_128913881 43.223 NM_018990
SASH3
SAM and SH3 domain containing 3
chr11_+_71927818 37.976 NM_000803
NM_001113534
NM_001113535
NM_001113536
FOLR2



folate receptor 2 (fetal)



chrX_+_128913897 37.425 SASH3
SAM and SH3 domain containing 3
chr3_-_195310985 37.392 NM_001647
APOD
apolipoprotein D
chr18_+_21572736 36.141 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr19_+_507475 33.730 NM_033513
TPGS1
tubulin polyglutamylase complex subunit 1
chr7_+_142560512 31.217 EPHB6
EPH receptor B6
chr6_+_6588933 29.726 NM_004271
LY86
lymphocyte antigen 86
chr3_-_20227618 28.854 NM_001012409
NM_001012410
NM_001012411
NM_001012412
NM_001012413
NM_138484
NM_001199251
NM_001199252
NM_001199253
NM_001199254
NM_001199255
NM_001199256
NM_001199257
SGOL1












shugoshin-like 1 (S. pombe)












chr14_-_106208537 28.825


chr3_-_195310770 28.683 APOD
apolipoprotein D
chr14_-_107013474 27.671 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr21_-_46340821 27.316 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_17186569 26.642 NM_001130065
NM_004145
MYO9B

myosin IXB

chr5_+_36608430 26.279 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_112194648 26.067 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr6_-_112194430 26.054 FYN
FYN oncogene related to SRC, FGR, YES
chr9_-_72873739 25.443 LOC100507299
uncharacterized LOC100507299
chr17_+_53342356 25.360 HLF
hepatic leukemia factor
chr1_+_22979681 24.093 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr2_+_113816684 24.028 NM_012275
IL36RN
interleukin 36 receptor antagonist
chr11_+_2323236 23.752 NM_139022
TSPAN32
tetraspanin 32
chr18_-_53068755 23.200 TCF4
transcription factor 4
chr3_+_133494275 22.877 TF
transferrin
chr14_-_24777153 22.426 CIDEB
cell death-inducing DFFA-like effector b
chr11_+_2323356 22.313 TSPAN32
tetraspanin 32
chrX_+_70364707 21.691 NLGN3
neuroligin 3
chr14_+_21359542 21.064 NM_002935
RNASE3
ribonuclease, RNase A family, 3
chr22_+_41957011 20.569 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr21_+_27012045 20.471 JAM2
junctional adhesion molecule 2
chr2_-_27718098 20.334 NM_022823
FNDC4
fibronectin type III domain containing 4
chr14_-_24777064 20.067


chr1_+_26644458 20.024 CD52
CD52 molecule
chr2_+_219246751 19.947 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chrX_+_70364728 19.702 NLGN3
neuroligin 3
chr20_-_1165116 19.397 NM_018354
TMEM74B
transmembrane protein 74B
chr13_+_31309690 19.219 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr1_-_160681552 18.973 NM_001778
CD48
CD48 molecule
chr15_+_68908878 18.971 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chrX_+_70364680 18.504 NM_001166660
NM_018977
NM_181303
NLGN3


neuroligin 3


chr14_-_24423329 18.296 C14orf167
chromosome 14 open reading frame 167
chr22_+_24999113 18.205 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr19_+_50016500 17.959 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_29674564 17.863 SPN
sialophorin
chr8_+_21916858 17.836 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr7_+_99816870 17.367 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr11_-_63330854 16.956 NM_017878
HRASLS2
HRAS-like suppressor 2
chr12_+_49688908 16.929 NM_006262
PRPH
peripherin
chr22_-_36556781 16.866 NM_145640
APOL3
apolipoprotein L, 3
chr11_+_46722316 16.830 NM_024741
ZNF408
zinc finger protein 408
chr22_+_23063107 16.793 IGLJ3
immunoglobulin lambda joining 3
chr10_-_90712510 16.623 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_-_27718059 16.454 FNDC4
fibronectin type III domain containing 4
chr14_-_107078578 16.319


chr5_+_36606456 16.148 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr2_-_228497801 16.099 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr4_-_174320616 15.839 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr12_-_57630867 15.596 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr6_+_134210247 15.569 NM_198392
NM_003206
TCF21

transcription factor 21

chr1_-_156399183 15.537 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr1_+_26644380 15.529 NM_001803
CD52
CD52 molecule
chr17_+_40913233 15.529 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr14_-_24777160 15.518 CIDEB
cell death-inducing DFFA-like effector b
chr11_+_121461070 15.490 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_150399980 15.395 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr3_-_39321479 15.284 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr11_-_5271035 15.254 NM_000559
HBG1
hemoglobin, gamma A
chrX_+_103031433 15.230 NM_001128834
PLP1
proteolipid protein 1
chrY_+_1405508 15.210 NM_002183
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr12_-_53600999 15.155 NM_000889
ITGB7
integrin, beta 7
chr16_+_6069094 15.124 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chrX_+_1455508 14.999 NM_002183
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr1_+_156123321 14.954 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr5_+_36606667 14.851 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_4455285 14.794 NM_001171091
UBXN6
UBX domain protein 6
chr14_-_106774311 14.771 IGHA1
immunoglobulin heavy constant alpha 1
chr6_+_33043702 14.616 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr2_+_3642421 14.461 NM_024027
NM_199235
COLEC11

collectin sub-family member 11

chr11_-_2158510 14.301 IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_+_118827007 14.197 NM_006760
UPK2
uroplakin 2
chr16_-_89556886 14.187 NM_013275
ANKRD11
ankyrin repeat domain 11
chr12_-_110271182 14.113 TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr22_+_51176623 13.957 NM_001097
ACR
acrosin
chr6_+_134210264 13.920 TCF21
transcription factor 21
chr12_-_7245048 13.877 C1R
complement component 1, r subcomponent
chr14_-_106111114 13.856 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr2_-_31637553 13.805 XDH
xanthine dehydrogenase
chr19_-_8642297 13.771 MYO1F
myosin IF
chr15_+_74422742 13.762 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr14_-_106746056 13.720


chrX_+_69672356 13.647 DLG3
discs, large homolog 3 (Drosophila)
chr21_-_46340776 13.538 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_+_125137600 13.519 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_148415657 13.480 NM_000685
NM_004835
NM_009585
NM_031850
AGTR1



angiotensin II receptor, type 1



chr6_-_46889620 13.445 NM_001098518
GPR116
G protein-coupled receptor 116
chr2_+_97202463 13.379 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr9_+_124086842 13.360 GSN
gelsolin
chr1_-_59012379 13.258 NM_145243
OMA1
OMA1 zinc metallopeptidase homolog (S. cerevisiae)
chrX_+_103031797 13.154 PLP1
proteolipid protein 1
chr16_-_20587625 13.122 NM_001105069
NM_182617
ACSM2B

acyl-CoA synthetase medium-chain family member 2B

chr19_-_42931500 13.115 NM_005357
LIPE
lipase, hormone-sensitive
chr13_+_31309644 13.092 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr15_-_29862926 12.881 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr11_-_64527369 12.757 PYGM
phosphorylase, glycogen, muscle
chrX_-_32173585 12.752 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr19_+_36359346 12.751 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr19_-_8642337 12.527 MYO1F
myosin IF
chr1_+_36772696 12.487 NM_024676
SH3D21
SH3 domain containing 21
chr6_-_46922533 12.455 NM_015234
GPR116
G protein-coupled receptor 116
chr11_-_2323066 12.334 NM_001142946
C11orf21
chromosome 11 open reading frame 21
chr3_+_123813527 12.247 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr16_+_20462858 12.166 NM_001010845
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr14_-_106092256 12.143 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr12_+_41086189 12.040 NM_001843
NM_175038
CNTN1

contactin 1

chr12_-_7245006 11.991 NM_001733
C1R
complement component 1, r subcomponent
chr10_-_99531712 11.904 NM_003015
SFRP5
secreted frizzled-related protein 5
chr8_-_19540093 11.825 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr12_+_54891539 11.790 NCKAP1L
NCK-associated protein 1-like
chr13_-_46742678 11.775 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_8642309 11.597 NM_012335
MYO1F
myosin IF
chr11_+_71903172 11.550 NM_016729
FOLR1
folate receptor 1 (adult)
chr17_+_40913211 11.519 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chrY_+_15016018 11.515 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr16_+_28505920 11.510 NM_018690
APOBR
apolipoprotein B receptor
chr17_+_14204326 11.492 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr19_-_36304200 11.467 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr3_+_195447751 11.284 NM_152673
MUC20
mucin 20, cell surface associated
chr12_-_110271205 11.152 NM_021625
TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr5_-_41261539 11.132 NM_001115131
C6
complement component 6
chr2_-_89513056 11.051 IGKC
immunoglobulin kappa constant
chr11_-_119999516 11.030 TRIM29
tripartite motif containing 29
chr11_+_60197061 10.967 NM_023945
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr17_-_42345434 10.966 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr14_-_106209380 10.961 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_94953827 10.895 NM_000446
PON1
paraoxonase 1
chrX_-_55057408 10.868 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr1_+_150245182 10.857 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr17_+_53342320 10.812 NM_002126
HLF
hepatic leukemia factor
chr1_-_167883243 10.591 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr9_-_4742042 10.565 NM_001199853
AK3
adenylate kinase 3
chr11_-_57004674 10.510 NM_005161
APLNR
apelin receptor
chr10_-_71176567 10.509 NM_001057
TACR2
tachykinin receptor 2
chr15_-_43513024 10.448 EPB42
erythrocyte membrane protein band 4.2
chr14_-_106237675 10.439 IGHM
immunoglobulin heavy constant mu
chr19_+_55587220 10.404 NM_133180
EPS8L1
EPS8-like 1
chr17_-_56358161 10.341 MPO
myeloperoxidase
chr19_-_54850385 10.331 NM_012276
LILRA4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr3_+_112052020 10.295 CD200
CD200 molecule
chr2_+_238475216 10.287 NM_015893
PRLH
prolactin releasing hormone
chr14_-_107170400 10.227 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr2_-_25474948 10.226 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr22_+_22712091 10.178 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr1_-_201081693 10.146 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_-_160549226 10.118 CD84
CD84 molecule
chr12_-_53601051 10.079 ITGB7
integrin, beta 7
chr10_-_75401492 9.870 NM_021245
MYOZ1
myozenin 1
chr5_-_137071462 9.826 KLHL3
kelch-like 3 (Drosophila)
chr2_+_189839132 9.820 COL3A1
collagen, type III, alpha 1
chr11_-_55703875 9.771 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr20_-_43883183 9.756 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr8_-_86290333 9.715 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr22_+_25003610 9.664 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr11_-_89650877 9.421 NM_001206627
LOC399939
ring finger protein 18-like
chr15_-_43513234 9.381 NM_000119
NM_001114134
EPB42

erythrocyte membrane protein band 4.2

chr14_-_106471439 9.348 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr16_-_31146992 9.301 PRSS8
protease, serine, 8
chr18_+_29171729 9.273 NM_000371
TTR
transthyretin
chr2_+_169921298 9.229 NM_005771
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr9_-_4741798 9.209 NM_001199855
AK3
adenylate kinase 3
chr3_+_9834201 9.209 NM_001198793
NM_005718
ARPC4-TTLL3
ARPC4
ARPC4-TTLL3 readthrough
actin related protein 2/3 complex, subunit 4, 20kDa
chr22_+_38004454 9.192 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr14_-_106405633 9.173 IGHM
immunoglobulin heavy constant mu
chr19_+_50936159 9.107 NM_004533
MYBPC2
myosin binding protein C, fast type
chr1_+_92632608 9.099 NM_015237
KIAA1107
KIAA1107
chr2_+_113763448 9.002 NM_014440
IL36A
interleukin 36, alpha
chr19_-_48614013 8.933 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chrX_-_13338517 8.910 NM_001135995
ATXN3L
ataxin 3-like
chr2_+_113875469 8.900 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr15_+_74421986 8.890 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_+_110731061 8.820 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr7_-_143966380 8.803 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr3_+_108015392 8.800 HHLA2
HERV-H LTR-associating 2
chr16_+_57438678 8.761 NM_002987
CCL17
chemokine (C-C motif) ligand 17
chr7_+_143880547 8.748 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr4_+_74281884 8.737 ALB
albumin
chr17_-_38074842 8.714 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr3_+_112051914 8.698 NM_001004196
NM_005944
CD200

CD200 molecule

chr16_-_20338808 8.686 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr1_-_173446273 8.682 LOC100506023
uncharacterized LOC100506023
chr21_-_46340874 8.593 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_26485510 8.577 NM_024869
FAM110D
family with sequence similarity 110, member D
chr6_-_161087406 8.567 NM_005577
LPA
lipoprotein, Lp(a)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.40 4.58e-05 GO:0023052 signaling
2.39 6.22e-05 GO:0050776 regulation of immune response
3.44 6.73e-05 GO:0006936 muscle contraction
3.29 1.02e-04 GO:0003012 muscle system process
1.95 4.76e-04 GO:0007267 cell-cell signaling
1.29 5.41e-04 GO:0032501 multicellular organismal process
1.24 1.41e-03 GO:0050896 response to stimulus
1.77 1.45e-03 GO:0007154 cell communication
1.91 1.71e-03 GO:0006955 immune response
1.53 1.98e-03 GO:0048583 regulation of response to stimulus
1.67 2.24e-03 GO:0002376 immune system process
1.19 2.63e-03 GO:0065007 biological regulation
2.58 1.33e-02 GO:0008202 steroid metabolic process
1.29 1.39e-02 GO:0051716 cellular response to stimulus
10.46 1.80e-02 GO:0001516 prostaglandin biosynthetic process
10.46 1.80e-02 GO:0046457 prostanoid biosynthetic process
1.70 1.91e-02 GO:0006629 lipid metabolic process
1.33 2.11e-02 GO:0007165 signal transduction
8.14 2.37e-02 GO:0006693 prostaglandin metabolic process
1.83 2.61e-02 GO:0002682 regulation of immune system process
6.70 2.93e-02 GO:0006692 prostanoid metabolic process
4.70 3.26e-02 GO:0006690 icosanoid metabolic process
2.05 4.03e-02 GO:0007268 synaptic transmission
1.42 4.19e-02 GO:0065008 regulation of biological quality
5.54 4.73e-02 GO:0046456 icosanoid biosynthetic process
3.66 4.95e-02 GO:0006959 humoral immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.85 1.26e-13 GO:0005576 extracellular region
1.81 3.15e-13 GO:0044459 plasma membrane part
2.04 4.77e-11 GO:0005887 integral to plasma membrane
2.01 1.68e-10 GO:0031226 intrinsic to plasma membrane
2.28 8.68e-10 GO:0005615 extracellular space
1.46 8.88e-10 GO:0005886 plasma membrane
1.45 1.58e-09 GO:0071944 cell periphery
2.05 3.86e-09 GO:0044421 extracellular region part
1.80 1.40e-05 GO:0000267 cell fraction
1.78 1.09e-03 GO:0005626 insoluble fraction
1.78 1.44e-03 GO:0005624 membrane fraction
1.18 2.85e-03 GO:0016020 membrane
2.27 5.84e-03 GO:0015629 actin cytoskeleton
1.20 5.94e-03 GO:0044425 membrane part
2.01 2.31e-02 GO:0009986 cell surface
6.98 4.14e-02 GO:0032982 myosin filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.58 4.27e-04 GO:0019825 oxygen binding
5.76 8.76e-04 GO:0003823 antigen binding
1.43 5.64e-03 GO:0004871 signal transducer activity
1.43 5.64e-03 GO:0060089 molecular transducer activity
1.49 5.72e-03 GO:0004872 receptor activity
2.12 6.72e-03 GO:0030246 carbohydrate binding
2.91 8.35e-03 GO:0004252 serine-type endopeptidase activity
2.53 1.94e-02 GO:0005529 sugar binding
2.63 2.37e-02 GO:0008236 serine-type peptidase activity
2.59 3.08e-02 GO:0017171 serine hydrolase activity
3.17 3.36e-02 GO:0005179 hormone activity
2.01 4.64e-02 GO:0004175 endopeptidase activity