Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.671


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SSRP1chr11_-_57103324-0.756.9e-41Click!
HMGB3chrX_+_150151757-0.681.9e-30Click!
HMGB2chr4_-_174255454-0.621.9e-24Click!
UBTFchr17_-_42296865-0.313.3e-06Click!
HBP1chr7_+_1068094050.269.6e-05Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_52988916 48.464 NM_001243234
NM_001243235
TCF4

transcription factor 4

chrX_-_13835187 40.991 GPM6B
glycoprotein M6B
chr12_-_16757944 38.471 LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_89790412 37.966 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_89790464 35.709 PNRC1
proline-rich nuclear receptor coactivator 1
chrX_-_13835012 34.599 GPM6B
glycoprotein M6B
chrX_-_13835213 33.494 GPM6B
glycoprotein M6B
chr17_+_36861398 33.484 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr11_+_57365577 31.555 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr18_-_53177999 31.139 NM_001243231
TCF4
transcription factor 4
chrX_-_13835313 29.596 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr12_-_91573264 29.182 NM_133503
DCN
decorin
chr11_+_57365026 29.048 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr3_+_39509069 27.570 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr6_+_99872769 27.535


chr14_-_92413738 27.471 FBLN5
fibulin 5
chr12_-_91576579 26.889 DCN
decorin
chr18_-_53071225 26.623 NM_001243232
TCF4
transcription factor 4
chr2_+_149633173 26.020


chr12_-_16760935 25.942 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr11_+_112831968 25.640 NM_000615
NM_001076682
NM_001242607
NM_001242608
NM_181351
NCAM1




neural cell adhesion molecule 1




chr10_+_70847857 25.591 SRGN
serglycin
chr12_-_9268440 25.417 A2M
alpha-2-macroglobulin
chrX_+_135251795 25.208 NM_001167819
FHL1
four and a half LIM domains 1
chr18_-_53257033 24.299 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr10_+_70847817 23.923 NM_002727
SRGN
serglycin
chr12_-_9268513 23.747 A2M
alpha-2-macroglobulin
chr18_+_72922725 23.675 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_36748164 23.378 THRAP3
thyroid hormone receptor associated protein 3
chr4_-_88450243 23.293 SPARCL1
SPARC-like 1 (hevin)
chr3_-_114790221 22.991 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_30934437 22.399 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr7_-_111846384 22.260 NM_014705
DOCK4
dedicator of cytokinesis 4
chr4_-_186877413 21.518 SORBS2
sorbin and SH3 domain containing 2
chrX_+_135251454 21.342 NM_001159704
FHL1
four and a half LIM domains 1
chr19_-_17375522 21.126 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr12_-_16758839 21.080 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16759430 21.044 LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_88450601 20.880 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr14_-_92414004 20.578 NM_006329
FBLN5
fibulin 5
chrX_+_64708614 20.073 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr4_+_110749149 20.030 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_-_111782447 19.079 NM_001885
CRYAB
crystallin, alpha B
chr12_-_16758312 19.009 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_+_45971249 19.006 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr12_-_16759531 18.626 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_32163890 18.565 NOTCH4
notch 4
chr18_-_74729049 18.107 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr4_-_2263808 18.098 MXD4
MAX dimerization protein 4
chr18_-_74728963 17.926 MBP
myelin basic protein
chr12_-_9268475 17.865 A2M
alpha-2-macroglobulin
chr11_+_67007484 17.843 LOC100131150
uncharacterized LOC100131150
chr5_+_170736287 17.344 NM_021025
TLX3
T-cell leukemia homeobox 3
chr3_-_114478117 17.006 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr2_+_143886898 16.964 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr2_+_74120132 16.904 ACTG2
actin, gamma 2, smooth muscle, enteric
chr5_-_11903964 16.879 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr12_-_11548485 16.855 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr11_-_117747331 16.835 FXYD6
FXYD domain containing ion transport regulator 6
chr2_+_74120092 16.674 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr4_-_176733413 16.482 GPM6A
glycoprotein M6A
chr3_+_111717585 16.214 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr4_+_78078394 16.025 CCNG2
cyclin G2
chr3_-_14988976 16.020 LOC100505641
uncharacterized LOC100505641
chr7_-_27205148 15.551 NM_152739
HOXA9
homeobox A9
chr11_+_71791376 15.538 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr5_-_146435589 15.306 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr2_+_189839132 15.301 COL3A1
collagen, type III, alpha 1
chr2_+_143886969 15.243 ARHGAP15
Rho GTPase activating protein 15
chr4_-_186577858 15.207 SORBS2
sorbin and SH3 domain containing 2
chr3_-_14988939 15.151 LOC100505641
uncharacterized LOC100505641
chr12_-_10282680 15.092 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr12_-_6233684 14.739 NM_000552
VWF
von Willebrand factor
chr2_-_157189040 14.699 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_-_226926875 14.609 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr2_-_86564632 14.497 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr15_+_66994669 14.480 NM_005585
SMAD6
SMAD family member 6
chr10_+_63661012 14.435 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_+_169923531 14.395 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_-_32497925 14.348 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr9_-_95298251 14.348 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr11_+_128564130 14.340 FLI1
Friend leukemia virus integration 1
chr4_-_5890142 14.281 CRMP1
collapsin response mediator protein 1
chr11_+_128563955 14.187 FLI1
Friend leukemia virus integration 1
chr6_-_32557431 14.098 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr5_+_172483285 14.086 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr1_-_201476218 14.063 CSRP1
cysteine and glycine-rich protein 1
chr2_+_203499819 14.018 NM_173511
FAM117B
family with sequence similarity 117, member B
chr2_+_90211704 13.790


chr7_-_37025696 13.775 ELMO1
engulfment and cell motility 1
chr1_+_244998592 13.764 NM_198076
FAM36A
family with sequence similarity 36, member A
chr4_-_71532341 13.760 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_208989081 13.752 NM_006891
CRYGD
crystallin, gamma D
chr15_+_93443418 13.675 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr11_+_112832089 13.666 NCAM1
neural cell adhesion molecule 1
chr14_-_50697940 13.625 SOS2
son of sevenless homolog 2 (Drosophila)
chr1_-_182360400 13.558 NM_001033056
GLUL
glutamate-ammonia ligase
chr3_+_122044010 13.444 NM_005213
CSTA
cystatin A (stefin A)
chr1_+_156589085 13.373 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr2_-_174767282 13.291


chr19_+_58790306 13.287 NM_021089
ZNF8
zinc finger protein 8
chr3_-_58563070 13.276 FAM107A
family with sequence similarity 107, member A
chr9_-_23826062 13.267 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr8_-_72273965 13.246 EYA1
eyes absent homolog 1 (Drosophila)
chr11_+_113931228 13.206 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr3_-_47933997 13.184 MAP4
microtubule-associated protein 4
chr3_-_187454247 13.083 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr2_+_162272892 13.053 TBR1
T-box, brain, 1
chr8_-_33424642 13.038 NM_024787
RNF122
ring finger protein 122
chr4_-_186732047 13.038 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr1_+_201476283 12.995


chr3_-_114343052 12.951 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_140739589 12.869 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr12_-_16759939 12.691 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_14989399 12.627 LOC100505641
uncharacterized LOC100505641
chr4_-_101439071 12.605 NM_001159694
NM_016242
EMCN

endomucin

chr2_-_128421965 12.413 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr5_-_169724614 12.397 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_201476248 12.291 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr4_+_175204827 12.277 NM_001040157
CEP44
centrosomal protein 44kDa
chr20_+_20348744 12.240 NM_002196
INSM1
insulinoma-associated 1
chr1_-_57045129 12.222 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_-_3930713 12.117 CREBBP
CREB binding protein
chr20_+_17207680 12.099 PCSK2
proprotein convertase subtilisin/kexin type 2
chr7_-_27183225 12.057 NM_019102
HOXA5
homeobox A5
chr7_-_137028433 12.013 PTN
pleiotrophin
chr1_-_201476241 11.960 CSRP1
cysteine and glycine-rich protein 1
chr4_-_2263706 11.957 NM_006454
MXD4
MAX dimerization protein 4
chr1_+_198608244 11.920 PTPRC
protein tyrosine phosphatase, receptor type, C
chr19_-_40324747 11.907 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr8_+_22210311 11.890 PIWIL2
piwi-like 2 (Drosophila)
chr14_-_60097531 11.846 NM_206852
RTN1
reticulon 1
chr18_-_53255361 11.825 TCF4
transcription factor 4
chr1_-_201475966 11.737 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr7_+_111846736 11.674 ZNF277
zinc finger protein 277
chr17_-_37764165 11.664 NM_006160
NEUROD2
neurogenic differentiation 2
chr2_-_136873740 11.524 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr4_-_186732208 11.479 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr6_+_148664124 11.451 SASH1
SAM and SH3 domain containing 1
chr16_-_31085503 11.403 NM_024706
ZNF668
zinc finger protein 668
chr5_+_15500288 11.377 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr11_+_128563993 11.367 FLI1
Friend leukemia virus integration 1
chr18_+_7946885 11.291 PTPRM
protein tyrosine phosphatase, receptor type, M
chr9_-_77503009 11.231 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr11_+_73359734 11.224 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr16_+_31085722 11.212 NM_014699
ZNF646
zinc finger protein 646
chr7_-_27187367 11.209 NM_024014
HOXA6
homeobox A6
chr1_-_57888785 11.196 DAB1
disabled homolog 1 (Drosophila)
chr17_+_3100809 11.179 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr15_+_25200069 11.173 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr1_+_155853546 11.138 SYT11
synaptotagmin XI
chr2_-_216259197 11.112 FN1
fibronectin 1
chr19_+_56166418 11.101 U2AF2
U2 small nuclear RNA auxiliary factor 2
chr2_+_148602050 11.051 ACVR2A
activin A receptor, type IIA
chr12_-_11508509 11.044 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chr2_-_218843541 11.044 TNS1
tensin 1
chr8_-_87755880 11.044 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr7_-_137028275 11.003 PTN
pleiotrophin
chr6_+_7108864 10.993 RREB1
ras responsive element binding protein 1
chr16_+_31085751 10.906 ZNF646
zinc finger protein 646
chr8_+_26435920 10.891 NM_001244604
DPYSL2
dihydropyrimidinase-like 2
chr9_-_36400817 10.888 NM_194328
NM_194332
RNF38

ring finger protein 38

chr5_+_140797270 10.887 PCDHGB7
protocadherin gamma subfamily B, 7
chr4_+_3294711 10.866 RGS12
regulator of G-protein signaling 12
chr1_-_57045214 10.854 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_115934363 10.797 NM_018017
C10orf118
chromosome 10 open reading frame 118
chr4_-_176733901 10.728 GPM6A
glycoprotein M6A
chr12_+_52445185 10.689 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr7_+_30960914 10.681 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr11_+_112832201 10.681 NCAM1
neural cell adhesion molecule 1
chr12_-_10251520 10.674 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr22_-_50523737 10.672 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr13_-_67804432 10.656 NM_020403
NM_203487
PCDH9

protocadherin 9

chr22_-_19512859 10.654 NM_001130861
NM_003277
CLDN5

claudin 5

chr6_-_134496833 10.645 SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_36861857 10.556 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr7_+_106505696 10.538 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_195306274 10.533 APOD
apolipoprotein D
chr1_+_244998967 10.524 FAM36A
family with sequence similarity 36, member A
chr3_-_66024508 10.517 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr5_+_140864626 10.496 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr1_+_39875175 10.482 NM_015038
KIAA0754
KIAA0754
chr7_-_137028370 10.414 PTN
pleiotrophin
chr4_+_159690208 10.412 FNIP2
folliculin interacting protein 2
chr9_-_123476578 10.386 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr20_+_17207596 10.386 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr6_-_152957985 10.376 NM_033071
SYNE1
spectrin repeat containing, nuclear envelope 1
chr4_+_175205044 10.365 NM_001145314
CEP44
centrosomal protein 44kDa
chr22_-_50523780 10.347 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_+_128563973 10.296 FLI1
Friend leukemia virus integration 1
chr6_+_41040713 10.266 NFYA
nuclear transcription factor Y, alpha
chr16_+_31271327 10.230 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr18_-_13915534 10.228 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr1_-_57045235 10.211 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_163113129 10.189 RGS5
regulator of G-protein signaling 5
chr17_+_30814708 10.064


chr2_+_12857885 10.063 TRIB2
tribbles homolog 2 (Drosophila)
chr1_-_182360181 10.059 GLUL
glutamate-ammonia ligase
chr6_-_134498973 10.042 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_-_50698090 10.018 NM_006939
SOS2
son of sevenless homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.57 2.19e-33 GO:0032502 developmental process
1.57 1.04e-29 GO:0007275 multicellular organismal development
1.42 4.05e-29 GO:0032501 multicellular organismal process
1.59 8.64e-28 GO:0048856 anatomical structure development
1.59 1.24e-24 GO:0048731 system development
1.26 1.32e-22 GO:0065007 biological regulation
1.84 2.08e-22 GO:0007399 nervous system development
1.27 5.25e-20 GO:0050789 regulation of biological process
1.45 7.84e-20 GO:0023052 signaling
1.28 1.97e-19 GO:0050794 regulation of cellular process
1.62 9.58e-18 GO:0030154 cell differentiation
1.75 1.08e-17 GO:0009653 anatomical structure morphogenesis
1.60 2.02e-17 GO:0048869 cellular developmental process
1.15 2.04e-17 GO:0009987 cellular process
1.42 4.83e-15 GO:0007165 signal transduction
1.26 3.21e-13 GO:0050896 response to stimulus
1.34 7.81e-13 GO:0051716 cellular response to stimulus
2.54 3.54e-12 GO:0016337 cell-cell adhesion
1.92 5.10e-12 GO:0007155 cell adhesion
1.92 5.10e-12 GO:0022610 biological adhesion
2.03 1.58e-11 GO:0009887 organ morphogenesis
1.52 4.06e-11 GO:0048513 organ development
3.24 8.41e-11 GO:0007156 homophilic cell adhesion
1.89 3.68e-10 GO:0030182 neuron differentiation
1.62 4.71e-10 GO:0051239 regulation of multicellular organismal process
1.76 5.24e-10 GO:0022008 neurogenesis
1.51 5.35e-10 GO:0007166 cell surface receptor linked signaling pathway
1.77 1.04e-09 GO:0048699 generation of neurons
1.83 1.44e-09 GO:2000026 regulation of multicellular organismal development
1.45 1.69e-09 GO:0048523 negative regulation of cellular process
1.39 1.93e-09 GO:0048518 positive regulation of biological process
1.76 2.68e-09 GO:0040011 locomotion
1.41 2.88e-09 GO:0048522 positive regulation of cellular process
2.01 5.26e-09 GO:0000904 cell morphogenesis involved in differentiation
1.41 9.77e-09 GO:0048519 negative regulation of biological process
1.73 1.17e-08 GO:0006351 transcription, DNA-dependent
1.70 1.74e-08 GO:0050793 regulation of developmental process
2.07 2.80e-08 GO:0007409 axonogenesis
2.04 3.70e-08 GO:0048667 cell morphogenesis involved in neuron differentiation
2.21 5.34e-08 GO:0051093 negative regulation of developmental process
1.79 1.40e-07 GO:0045595 regulation of cell differentiation
1.44 1.58e-07 GO:0048583 regulation of response to stimulus
1.98 2.43e-07 GO:0048812 neuron projection morphogenesis
1.66 2.50e-07 GO:0048468 cell development
1.81 3.28e-07 GO:0032989 cellular component morphogenesis
1.47 4.48e-07 GO:0023051 regulation of signaling
1.82 5.01e-07 GO:0000902 cell morphogenesis
1.81 2.15e-06 GO:0048666 neuron development
1.86 2.25e-06 GO:0007417 central nervous system development
1.59 3.93e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.20 4.96e-06 GO:0045596 negative regulation of cell differentiation
1.59 5.07e-06 GO:0032774 RNA biosynthetic process
1.75 6.41e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.47 6.59e-06 GO:0009966 regulation of signal transduction
1.34 6.99e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 7.07e-06 GO:0042221 response to chemical stimulus
1.84 1.04e-05 GO:0031175 neuron projection development
1.72 1.06e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.82 1.25e-05 GO:0048858 cell projection morphogenesis
1.70 1.27e-05 GO:0010628 positive regulation of gene expression
2.02 1.80e-05 GO:0007411 axon guidance
1.33 1.85e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.04 1.86e-05 GO:0001501 skeletal system development
1.35 1.94e-05 GO:0006355 regulation of transcription, DNA-dependent
1.81 1.98e-05 GO:0032990 cell part morphogenesis
1.64 2.36e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.56 2.69e-05 GO:0045165 cell fate commitment
1.65 2.78e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.77 3.55e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.62 4.46e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.70 6.13e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.81 6.31e-05 GO:0072358 cardiovascular system development
1.81 6.31e-05 GO:0072359 circulatory system development
1.30 6.84e-05 GO:0031326 regulation of cellular biosynthetic process
2.62 6.88e-05 GO:0048705 skeletal system morphogenesis
1.53 7.54e-05 GO:0007154 cell communication
1.30 7.94e-05 GO:0009889 regulation of biosynthetic process
2.05 8.82e-05 GO:0007423 sensory organ development
1.33 8.82e-05 GO:0051252 regulation of RNA metabolic process
1.61 9.68e-05 GO:0007267 cell-cell signaling
1.25 9.95e-05 GO:0031323 regulation of cellular metabolic process
1.73 1.02e-04 GO:0051253 negative regulation of RNA metabolic process
1.87 1.03e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.26 1.23e-04 GO:0060255 regulation of macromolecule metabolic process
1.69 1.36e-04 GO:0010629 negative regulation of gene expression
1.57 1.54e-04 GO:0009891 positive regulation of biosynthetic process
1.57 1.70e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.64 1.84e-04 GO:0051254 positive regulation of RNA metabolic process
1.66 1.93e-04 GO:0030030 cell projection organization
1.65 1.97e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 2.05e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71 2.09e-04 GO:0006928 cellular component movement
1.30 2.17e-04 GO:0010468 regulation of gene expression
1.24 2.33e-04 GO:0080090 regulation of primary metabolic process
1.78 2.77e-04 GO:0048870 cell motility
1.78 2.77e-04 GO:0051674 localization of cell
1.63 2.90e-04 GO:0031327 negative regulation of cellular biosynthetic process
2.31 3.18e-04 GO:0030900 forebrain development
1.82 3.21e-04 GO:0016477 cell migration
1.22 4.90e-04 GO:0019222 regulation of metabolic process
1.61 4.91e-04 GO:0009890 negative regulation of biosynthetic process
1.75 5.49e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.65 5.50e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 5.56e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.86 6.32e-04 GO:0007420 brain development
2.07 6.62e-04 GO:0003002 regionalization
1.71 7.07e-04 GO:0006935 chemotaxis
1.71 7.07e-04 GO:0042330 taxis
2.91 8.55e-04 GO:0048706 embryonic skeletal system development
1.54 8.60e-04 GO:0051128 regulation of cellular component organization
1.75 8.93e-04 GO:0051094 positive regulation of developmental process
2.88 1.13e-03 GO:0055123 digestive system development
1.94 1.16e-03 GO:0051270 regulation of cellular component movement
1.59 1.24e-03 GO:0009790 embryo development
1.48 1.35e-03 GO:0009605 response to external stimulus
2.99 1.40e-03 GO:0048565 digestive tract development
1.26 1.69e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.98 1.78e-03 GO:0008361 regulation of cell size
1.98 2.04e-03 GO:0030334 regulation of cell migration
3.09 2.24e-03 GO:0032526 response to retinoic acid
2.91 2.50e-03 GO:0033189 response to vitamin A
1.67 2.63e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.58 2.87e-03 GO:0009719 response to endogenous stimulus
1.95 3.07e-03 GO:2000145 regulation of cell motility
2.26 3.12e-03 GO:0048562 embryonic organ morphogenesis
1.40 3.96e-03 GO:0010033 response to organic substance
1.86 3.98e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.82 4.84e-03 GO:0032535 regulation of cellular component size
1.88 5.20e-03 GO:0001944 vasculature development
1.88 5.20e-03 GO:0040012 regulation of locomotion
1.84 5.41e-03 GO:0060284 regulation of cell development
1.58 6.21e-03 GO:0009725 response to hormone stimulus
1.77 6.22e-03 GO:0048598 embryonic morphogenesis
1.47 6.24e-03 GO:0031324 negative regulation of cellular metabolic process
1.37 6.82e-03 GO:0035556 intracellular signal transduction
1.79 7.19e-03 GO:0007389 pattern specification process
2.76 7.39e-03 GO:0030336 negative regulation of cell migration
2.76 7.39e-03 GO:2000146 negative regulation of cell motility
1.39 7.80e-03 GO:0002376 immune system process
1.71 8.42e-03 GO:0040008 regulation of growth
2.67 9.21e-03 GO:0051271 negative regulation of cellular component movement
1.38 9.67e-03 GO:0009893 positive regulation of metabolic process
1.21 9.70e-03 GO:0016043 cellular component organization
1.42 1.15e-02 GO:0010646 regulation of cell communication
2.05 1.24e-02 GO:0048732 gland development
1.69 1.25e-02 GO:0008285 negative regulation of cell proliferation
1.40 1.32e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.56 1.39e-02 GO:0021537 telencephalon development
2.56 1.39e-02 GO:0040013 negative regulation of locomotion
3.19 1.39e-02 GO:0001764 neuron migration
1.84 1.44e-02 GO:0030029 actin filament-based process
1.43 1.73e-02 GO:0009892 negative regulation of metabolic process
1.45 1.82e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.00 1.89e-02 GO:0045664 regulation of neuron differentiation
2.13 1.96e-02 GO:0009952 anterior/posterior pattern formation
2.06 1.97e-02 GO:0003012 muscle system process
1.38 1.98e-02 GO:0031325 positive regulation of cellular metabolic process
1.64 2.12e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.84 2.42e-02 GO:0048545 response to steroid hormone stimulus
1.27 2.52e-02 GO:0065008 regulation of biological quality
1.85 2.55e-02 GO:0001568 blood vessel development
1.65 2.69e-02 GO:0023057 negative regulation of signaling
2.95 2.79e-02 GO:0050680 negative regulation of epithelial cell proliferation
1.42 2.96e-02 GO:0042127 regulation of cell proliferation
1.70 3.36e-02 GO:0009792 embryo development ending in birth or egg hatching
1.64 3.50e-02 GO:0007268 synaptic transmission
1.59 3.64e-02 GO:0043065 positive regulation of apoptosis
3.22 4.09e-02 GO:0048663 neuron fate commitment
1.69 4.41e-02 GO:0043009 chordate embryonic development
1.41 4.63e-02 GO:0032879 regulation of localization
1.58 4.67e-02 GO:0043068 positive regulation of programmed cell death
1.42 4.73e-02 GO:0009611 response to wounding
1.44 4.79e-02 GO:0009888 tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.49 1.84e-13 GO:0044459 plasma membrane part
1.26 3.11e-08 GO:0005886 plasma membrane
1.26 4.22e-08 GO:0071944 cell periphery
1.78 1.71e-07 GO:0030054 cell junction
2.03 2.07e-06 GO:0005578 proteinaceous extracellular matrix
1.91 4.23e-06 GO:0031012 extracellular matrix
1.52 5.96e-06 GO:0044421 extracellular region part
1.45 2.58e-05 GO:0005887 integral to plasma membrane
1.43 4.05e-05 GO:0031226 intrinsic to plasma membrane
2.59 7.47e-05 GO:0044420 extracellular matrix part
1.78 1.05e-04 GO:0045202 synapse
1.91 1.58e-04 GO:0044456 synapse part
1.29 1.12e-03 GO:0005576 extracellular region
1.46 1.24e-03 GO:0042995 cell projection
3.69 1.42e-03 GO:0005581 collagen
1.99 2.46e-03 GO:0005911 cell-cell junction
1.65 9.03e-03 GO:0009986 cell surface
1.43 1.39e-02 GO:0005615 extracellular space
2.03 1.67e-02 GO:0045211 postsynaptic membrane
1.70 2.23e-02 GO:0015629 actin cytoskeleton
1.91 2.58e-02 GO:0030424 axon
2.09 3.69e-02 GO:0043292 contractile fiber
1.88 3.78e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.88 1.63e-16 GO:0001071 nucleic acid binding transcription factor activity
1.88 1.63e-16 GO:0003700 sequence-specific DNA binding transcription factor activity
1.12 7.89e-15 GO:0005488 binding
1.90 2.25e-11 GO:0043565 sequence-specific DNA binding
1.69 1.59e-10 GO:0030528 transcription regulator activity
1.79 1.92e-08 GO:0005509 calcium ion binding
1.17 9.54e-08 GO:0005515 protein binding
1.32 1.27e-05 GO:0003677 DNA binding
1.23 1.56e-05 GO:0043167 ion binding
1.23 2.08e-05 GO:0043169 cation binding
1.23 2.09e-05 GO:0046872 metal ion binding
1.93 6.23e-05 GO:0016563 transcription activator activity
1.90 1.12e-03 GO:0032403 protein complex binding
2.02 1.77e-03 GO:0000975 regulatory region DNA binding
2.02 1.77e-03 GO:0001067 regulatory region nucleic acid binding
2.02 1.77e-03 GO:0044212 transcription regulatory region DNA binding
2.90 2.95e-03 GO:0005178 integrin binding
2.01 3.26e-03 GO:0010843 promoter binding
2.43 4.22e-03 GO:0004222 metalloendopeptidase activity
1.56 6.50e-03 GO:0008092 cytoskeletal protein binding
4.98 1.24e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
4.69 2.37e-02 GO:0005212 structural constituent of eye lens
1.63 2.95e-02 GO:0000988 protein binding transcription factor activity
1.63 2.95e-02 GO:0000989 transcription factor binding transcription factor activity
1.66 4.26e-02 GO:0003779 actin binding
2.79 4.45e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.61 4.96e-02 GO:0003712 transcription cofactor activity