Motif ID: MYB.p2

Z-value: 6.227


Transcription factors associated with MYB.p2:

Gene SymbolEntrez IDGene Name
MYB 4602 v-myb myeloblastosis viral oncogene homolog (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBchr6_+_1355025210.237.6e-04Click!


Activity profile for motif MYB.p2.

activity profile for motif MYB.p2


Sorted Z-values histogram for motif MYB.p2

Sorted Z-values for motif MYB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_54863672 132.481 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr2_-_27632522 131.114 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr11_+_34073188 130.947 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr19_+_49497122 124.614 NM_006666
RUVBL2
RuvB-like 2 (E. coli)
chr1_+_154947147 119.130 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr2_-_27632464 115.206 NM_177983
PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr19_-_14529853 113.595 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr1_+_154947166 112.885 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_+_154947116 110.059 NM_001826
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr17_+_7155371 105.930 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr1_+_43824598 105.822 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr11_+_34073889 102.676 CAPRIN1
cell cycle associated protein 1
chr2_-_27632445 102.555 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr19_-_14530155 101.282 NM_005804
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr17_+_7155821 90.539 C17orf81
chromosome 17 open reading frame 81
chr4_-_100871482 88.485 NM_002106
H2AFZ
H2A histone family, member Z
chr4_-_100871431 87.497 H2AFZ
H2A histone family, member Z
chr17_+_66031814 83.556 NM_002266
KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr11_+_34073924 83.156 CAPRIN1
cell cycle associated protein 1
chr3_-_186857188 81.511 NM_052969
RPL39L
ribosomal protein L39-like
chr7_-_72993007 81.494 NM_012453
TBL2
transducin (beta)-like 2
chr9_+_131219185 80.138 NM_153437
ODF2
outer dense fiber of sperm tails 2
chr11_+_18433845 79.717 NM_002301
NM_017448
LDHC

lactate dehydrogenase C

chr9_+_140135698 79.526 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chr3_+_49059046 78.837 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chr13_-_103426148 78.384 NM_138779
C13orf27
chromosome 13 open reading frame 27
chr17_+_66031885 78.256 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr13_-_103426075 77.201 C13orf27
chromosome 13 open reading frame 27
chr3_+_52444673 76.059 PHF7
PHD finger protein 7
chr2_-_27632393 74.590 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr19_-_14530129 73.634 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr17_-_33288415 71.987 CCT6B
chaperonin containing TCP1, subunit 6B (zeta 2)
chr9_+_140135738 69.665 TUBB4B
tubulin, beta 4B class IVb
chr4_+_128703402 69.204 NM_014278
HSPA4L
heat shock 70kDa protein 4-like
chr2_-_27632288 66.683 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr9_+_140135742 65.534 TUBB4B
tubulin, beta 4B class IVb
chr7_-_72992908 65.504 TBL2
transducin (beta)-like 2
chr7_-_72992931 64.403 TBL2
transducin (beta)-like 2
chr3_+_52444952 63.430 PHF7
PHD finger protein 7
chr6_+_167412791 63.194 NM_007045
NM_194429
FGFR1OP

FGFR1 oncogene partner

chr15_-_91537724 62.145 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr4_-_100871418 61.342 H2AFZ
H2A histone family, member Z
chr3_+_49059490 60.718 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr1_+_45205533 60.412 KIF2C
kinesin family member 2C
chr17_+_33914320 59.873 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr17_+_33914357 59.361 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_72992888 56.696 TBL2
transducin (beta)-like 2
chr1_+_45205466 55.915 NM_006845
KIF2C
kinesin family member 2C
chr1_-_156308099 55.701 NM_001008800
NM_005998
CCT3

chaperonin containing TCP1, subunit 3 (gamma)

chr1_-_153643456 55.685 ILF2
interleukin enhancer binding factor 2, 45kDa
chr9_+_33025302 54.955 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr2_+_61244696 54.873 NM_002618
PEX13
peroxisomal biogenesis factor 13
chr9_+_33025207 54.509 NM_001539
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr4_+_128703480 54.376 HSPA4L
heat shock 70kDa protein 4-like
chr19_+_47634133 54.150 SAE1
SUMO1 activating enzyme subunit 1
chr9_+_33025270 53.491 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr11_-_47664014 53.366 NM_014342
MTCH2
mitochondrial carrier 2
chr1_-_153643474 53.344 NM_004515
ILF2
interleukin enhancer binding factor 2, 45kDa
chr19_+_47634044 53.316 NM_001145713
NM_001145714
NM_005500
SAE1


SUMO1 activating enzyme subunit 1


chr7_-_72992919 52.974 TBL2
transducin (beta)-like 2
chr19_+_47634148 52.841 SAE1
SUMO1 activating enzyme subunit 1
chr1_-_153643433 51.883 ILF2
interleukin enhancer binding factor 2, 45kDa
chr19_+_47634118 51.235 SAE1
SUMO1 activating enzyme subunit 1
chr5_+_151151514 51.231 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_+_155658881 51.162 NM_001199849
NM_001199850
NM_001199851
NM_004632
NM_033657
DAP3




death associated protein 3




chr1_+_155658873 51.017 DAP3
death associated protein 3
chr12_-_57081961 50.698 PTGES3
prostaglandin E synthase 3 (cytosolic)
chr12_+_110906203 50.462 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr2_-_61764661 50.322 XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_-_10875848 50.298 NM_001145426
NM_003651
CSDA

cold shock domain protein A

chr2_+_85766286 50.253 MAT2A
methionine adenosyltransferase II, alpha
chr10_-_43904306 50.245 NM_001098205
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_-_153643428 50.239 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_153643417 49.640 ILF2
interleukin enhancer binding factor 2, 45kDa
chr19_+_59056017 49.636 TRIM28
tripartite motif containing 28
chr1_+_43148359 49.602 YBX1
Y box binding protein 1
chr12_+_120933911 49.234 DYNLL1
dynein, light chain, LC8-type 1
chr12_-_109125289 48.890 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr8_-_101964236 48.880 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_-_57081923 48.802 PTGES3
prostaglandin E synthase 3 (cytosolic)
chr3_+_160117444 48.671 SMC4
structural maintenance of chromosomes 4
chr3_+_49058617 48.224 NM_199073
NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr1_+_43148105 48.090 YBX1
Y box binding protein 1
chr1_+_43148168 47.262 YBX1
Y box binding protein 1
chr17_+_30677138 47.191 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr15_+_40453209 46.871 NM_001211
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_-_1713914 46.764 NM_006527
SLBP
stem-loop binding protein
chr10_-_88281486 46.554 WAPAL
wings apart-like homolog (Drosophila)
chr7_+_87505543 46.072 NM_006716
DBF4
DBF4 homolog (S. cerevisiae)
chr12_+_120933916 45.763 DYNLL1
dynein, light chain, LC8-type 1
chrX_+_69509878 45.364 NM_012310
KIF4A
kinesin family member 4A
chr6_+_134274247 44.864 NM_004865
TBPL1
TBP-like 1
chr6_+_134273307 44.849 NM_001253676
TBPL1
TBP-like 1
chr17_+_30677178 44.713 ZNF207
zinc finger protein 207
chr5_+_137514416 44.636 NM_005733
KIF20A
kinesin family member 20A
chr7_-_105752650 44.375 SYPL1
synaptophysin-like 1
chr1_+_43148048 44.161 NM_004559
YBX1
Y box binding protein 1
chr12_-_57082056 43.957 NM_006601
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr12_-_109125275 43.859 CORO1C
coronin, actin binding protein, 1C
chr18_+_34409058 43.770 NM_020776
KIAA1328
KIAA1328
chr7_+_87505737 43.510 DBF4
DBF4 homolog (S. cerevisiae)
chr10_-_43904598 43.409 NM_004966
NM_001098204
HNRNPF

heterogeneous nuclear ribonucleoprotein F

chr17_+_30677187 43.402 ZNF207
zinc finger protein 207
chr1_+_43148096 43.227 YBX1
Y box binding protein 1
chr1_+_45205558 42.994 KIF2C
kinesin family member 2C
chr19_+_59055866 42.931 TRIM28
tripartite motif containing 28
chr2_-_69614321 42.843 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr8_-_101964268 41.953 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr7_-_72992839 41.870 TBL2
transducin (beta)-like 2
chr8_-_101965096 41.766 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr16_-_58163286 41.437 NM_013242
C16orf80
chromosome 16 open reading frame 80
chr5_-_43557520 41.189 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr12_+_67663364 41.150 CAND1
cullin-associated and neddylation-dissociated 1
chr13_-_103426130 40.455 C13orf27
chromosome 13 open reading frame 27
chr5_-_43557098 40.203 NM_006451
NM_182789
PAIP1

poly(A) binding protein interacting protein 1

chr22_-_41252646 40.164 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr16_-_58163181 40.117 C16orf80
chromosome 16 open reading frame 80
chr12_+_120933832 40.113 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr5_+_151151516 39.735 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr11_+_34073951 39.644 CAPRIN1
cell cycle associated protein 1
chr18_-_34409084 39.630 NM_015476
TPGS2
tubulin polyglutamylase complex subunit 2
chr12_-_93835659 39.552 UBE2N
ubiquitin-conjugating enzyme E2N
chr1_+_212209129 39.526 DTL
denticleless homolog (Drosophila)
chr8_-_101733735 39.372 PABPC1
poly(A) binding protein, cytoplasmic 1
chr19_+_47104490 39.309 NM_005184
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr15_+_40453263 39.148 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr12_-_109125254 38.914 CORO1C
coronin, actin binding protein, 1C
chr13_+_113863926 38.783 NM_001008895
CUL4A
cullin 4A
chr17_-_47439326 38.632 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr1_-_211848820 38.552 NM_001204182
NM_001204183
NM_002497
NEK2


NIMA (never in mitosis gene a)-related kinase 2


chr19_+_59055826 38.516 NM_005762
TRIM28
tripartite motif containing 28
chr17_-_33288475 38.286 NM_001193529
NM_001193530
NM_006584
CCT6B


chaperonin containing TCP1, subunit 6B (zeta 2)


chr18_-_34408948 38.247 TPGS2
tubulin polyglutamylase complex subunit 2
chr12_-_57081780 38.219 PTGES3
prostaglandin E synthase 3 (cytosolic)
chr20_+_30326903 38.210 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr1_-_32403888 38.038 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr18_-_34408845 37.643 TPGS2
tubulin polyglutamylase complex subunit 2
chr1_-_156307971 37.595 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr1_-_156308064 37.492 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr5_+_137514753 37.341 KIF20A
kinesin family member 20A
chr20_+_35807747 37.337 RPN2
ribophorin II
chr2_-_9770366 37.279 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr1_-_156308047 37.062 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr6_+_34725266 36.807 SNRPC
small nuclear ribonucleoprotein polypeptide C
chr1_+_155658898 36.788 DAP3
death associated protein 3
chr18_-_34408699 36.787 TPGS2
tubulin polyglutamylase complex subunit 2
chr20_+_35807695 36.765 RPN2
ribophorin II
chr8_-_101734938 36.535 PABPC1
poly(A) binding protein, cytoplasmic 1
chr10_+_70091767 36.485 NM_012207
NM_021644
HNRNPH3

heterogeneous nuclear ribonucleoprotein H3 (2H9)

chr8_+_42249278 36.417 NM_001135694
NM_005662
VDAC3

voltage-dependent anion channel 3

chr1_+_43148187 36.390 YBX1
Y box binding protein 1
chr13_+_50571137 36.198 NM_001007278
NM_005798
NM_052811
NM_213590
TRIM13



tripartite motif containing 13



chr2_-_9770999 36.181 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr12_-_110906007 36.145 GPN3
GPN-loop GTPase 3
chr2_+_242255365 36.137 SEPT2
septin 2
chr1_+_38158129 35.475 NM_018101
CDCA8
cell division cycle associated 8
chr4_+_146019155 35.281 NM_001040876
NM_002940
ABCE1

ATP-binding cassette, sub-family E (OABP), member 1

chr8_-_101734162 35.163 PABPC1
poly(A) binding protein, cytoplasmic 1
chr8_-_101964334 35.158 NM_145690
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr13_+_21714709 35.136 SAP18
Sin3A-associated protein, 18kDa
chr8_-_101964248 35.088 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_+_151151462 35.020 NM_005754
NM_198395
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr3_+_49057907 35.016 NM_199074
NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr20_-_34243118 34.922 RBM12
RNA binding motif protein 12
chr1_+_212208918 34.627 NM_016448
DTL
denticleless homolog (Drosophila)
chr8_-_53626991 34.364 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr19_+_47104559 34.282 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr2_-_47403652 34.252 CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr12_-_93835714 34.091 UBE2N
ubiquitin-conjugating enzyme E2N
chr3_+_52444514 34.084 NM_016483
NM_173341
PHF7

PHD finger protein 7

chr12_-_10875698 33.983 CSDA
cold shock domain protein A
chr8_-_101964197 33.837 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_+_70883856 33.592 NM_001035260
NM_004896
VPS26A

vacuolar protein sorting 26 homolog A (S. pombe)

chr12_-_93835723 33.288 UBE2N
ubiquitin-conjugating enzyme E2N
chr8_-_101964247 33.213 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_-_31479120 33.072 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr8_-_101734313 32.998 NM_002568
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_133306531 32.979 ANKLE2
ankyrin repeat and LEM domain containing 2
chr17_-_1303402 32.977 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr15_+_80352488 32.890 NM_001242914
ZFAND6
zinc finger, AN1-type domain 6
chr12_+_110906532 32.594 C12orf24
chromosome 12 open reading frame 24
chr8_-_101734290 32.392 PABPC1
poly(A) binding protein, cytoplasmic 1
chr16_+_66586518 32.366 CKLF
chemokine-like factor
chr7_-_148581403 32.195 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr3_+_160118346 32.179 NM_005496
SMC4
structural maintenance of chromosomes 4
chr12_-_31479038 32.084 FAM60A
family with sequence similarity 60, member A
chrX_-_129299680 31.916 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr8_+_42249393 31.905 VDAC3
voltage-dependent anion channel 3
chr10_+_70883977 31.762 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr20_+_35807522 31.612 RPN2
ribophorin II
chr1_+_38158189 31.491 CDCA8
cell division cycle associated 8
chr12_+_110906659 31.487 C12orf24
chromosome 12 open reading frame 24
chr14_-_23398563 31.462 PRMT5
protein arginine methyltransferase 5
chr22_-_41252636 31.359 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr1_-_155658794 31.194 NM_001198901
NM_001198906
NM_139118
YY1AP1


YY1 associated protein 1


chr11_+_63953630 31.022 STIP1
stress-induced-phosphoprotein 1
chr1_-_155658232 30.958 YY1AP1
YY1 associated protein 1
chr2_+_97001463 30.918 NM_015341
NCAPH
non-SMC condensin I complex, subunit H
chr1_-_167905078 30.693 BRP44
brain protein 44
chr9_+_131873592 30.481 NM_178000
NM_178001
NM_178003
PPP2R4


protein phosphatase 2A activator, regulatory subunit 4



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.72 4.55e-34 GO:0044260 cellular macromolecule metabolic process
1.50 4.07e-29 GO:0044237 cellular metabolic process
1.57 9.31e-26 GO:0043170 macromolecule metabolic process
1.46 3.68e-25 GO:0044238 primary metabolic process
1.83 1.59e-23 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.72 1.70e-22 GO:0006807 nitrogen compound metabolic process
1.73 4.24e-22 GO:0034641 cellular nitrogen compound metabolic process
1.39 1.73e-21 GO:0008152 metabolic process
1.90 3.14e-21 GO:0090304 nucleic acid metabolic process
2.87 2.11e-18 GO:0000278 mitotic cell cycle
2.00 1.16e-17 GO:0006996 organelle organization
1.21 2.64e-17 GO:0009987 cellular process
2.29 3.45e-17 GO:0007049 cell cycle
2.61 1.38e-16 GO:0022403 cell cycle phase
2.41 2.09e-15 GO:0022402 cell cycle process
1.67 6.63e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.70 1.01e-14 GO:0044267 cellular protein metabolic process
1.66 5.38e-14 GO:0071842 cellular component organization at cellular level
2.57 5.55e-14 GO:0051276 chromosome organization
1.85 7.93e-14 GO:0016070 RNA metabolic process
2.56 9.01e-12 GO:0016071 mRNA metabolic process
1.50 2.74e-11 GO:0071840 cellular component organization or biogenesis
3.07 4.62e-11 GO:0051325 interphase
3.07 7.89e-11 GO:0051329 interphase of mitotic cell cycle
1.73 9.34e-11 GO:0010467 gene expression
1.50 1.12e-10 GO:0016043 cellular component organization
3.04 1.26e-10 GO:0008380 RNA splicing
2.59 1.83e-10 GO:0006325 chromatin organization
2.76 2.39e-10 GO:0006397 mRNA processing
2.63 4.33e-10 GO:0000279 M phase
2.12 2.06e-09 GO:0046907 intracellular transport
1.51 2.39e-09 GO:0019538 protein metabolic process
2.25 3.02e-09 GO:0006396 RNA processing
2.91 3.80e-09 GO:0000087 M phase of mitotic cell cycle
4.32 9.76e-09 GO:0000086 G2/M transition of mitotic cell cycle
3.28 2.63e-08 GO:0000375 RNA splicing, via transesterification reactions
3.28 4.45e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.28 4.45e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
2.83 5.00e-08 GO:0000280 nuclear division
2.83 5.00e-08 GO:0007067 mitosis
2.79 5.12e-08 GO:0048285 organelle fission
2.57 1.50e-07 GO:0016568 chromatin modification
2.12 5.07e-07 GO:0051726 regulation of cell cycle
3.27 5.19e-07 GO:0006913 nucleocytoplasmic transport
3.79 7.27e-07 GO:0050657 nucleic acid transport
3.79 7.27e-07 GO:0050658 RNA transport
3.79 7.27e-07 GO:0051236 establishment of RNA localization
3.23 7.32e-07 GO:0051169 nuclear transport
2.74 9.17e-07 GO:0010608 posttranscriptional regulation of gene expression
3.49 1.65e-06 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
3.67 1.70e-06 GO:0006403 RNA localization
1.72 2.35e-06 GO:0051641 cellular localization
1.77 2.51e-06 GO:0051649 establishment of localization in cell
2.17 2.84e-06 GO:0044265 cellular macromolecule catabolic process
2.07 3.87e-06 GO:0009057 macromolecule catabolic process
2.45 4.01e-06 GO:0051301 cell division
2.20 5.35e-06 GO:0034621 cellular macromolecular complex subunit organization
2.07 7.29e-06 GO:0006259 DNA metabolic process
2.38 1.16e-05 GO:0034622 cellular macromolecular complex assembly
1.54 1.70e-05 GO:0006464 protein modification process
1.53 1.72e-05 GO:0043412 macromolecule modification
1.56 3.13e-05 GO:0009059 macromolecule biosynthetic process
2.54 3.54e-05 GO:0032446 protein modification by small protein conjugation
1.64 4.22e-05 GO:0033036 macromolecule localization
1.56 4.27e-05 GO:0034645 cellular macromolecule biosynthetic process
1.68 4.36e-05 GO:0044085 cellular component biogenesis
3.57 4.44e-05 GO:0051028 mRNA transport
2.83 5.00e-05 GO:0006457 protein folding
1.69 5.09e-05 GO:0044248 cellular catabolic process
2.34 5.64e-05 GO:0010564 regulation of cell cycle process
2.41 6.45e-05 GO:0006511 ubiquitin-dependent protein catabolic process
3.95 9.22e-05 GO:0051168 nuclear export
1.44 1.01e-04 GO:0044249 cellular biosynthetic process
2.36 1.20e-04 GO:0019941 modification-dependent protein catabolic process
2.33 1.22e-04 GO:0070647 protein modification by small protein conjugation or removal
2.50 1.23e-04 GO:0007346 regulation of mitotic cell cycle
2.34 1.47e-04 GO:0043632 modification-dependent macromolecule catabolic process
2.93 2.21e-04 GO:0006417 regulation of translation
2.48 2.27e-04 GO:0007017 microtubule-based process
2.30 2.67e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
2.85 2.68e-04 GO:0016570 histone modification
1.41 2.85e-04 GO:0009058 biosynthetic process
1.77 3.02e-04 GO:0043933 macromolecular complex subunit organization
2.48 3.36e-04 GO:0016567 protein ubiquitination
1.85 3.62e-04 GO:0065003 macromolecular complex assembly
2.80 4.06e-04 GO:0016569 covalent chromatin modification
2.25 4.75e-04 GO:0044257 cellular protein catabolic process
2.20 5.57e-04 GO:0030163 protein catabolic process
1.55 6.37e-04 GO:0009056 catabolic process
1.66 7.06e-04 GO:0022607 cellular component assembly
1.78 1.18e-03 GO:0071844 cellular component assembly at cellular level
3.97 1.64e-03 GO:0006405 RNA export from nucleus
2.12 2.82e-03 GO:0044419 interspecies interaction between organisms
2.70 4.87e-03 GO:0010498 proteasomal protein catabolic process
2.70 4.87e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.61 5.38e-03 GO:0032268 regulation of cellular protein metabolic process
1.29 5.81e-03 GO:0031323 regulation of cellular metabolic process
1.29 7.86e-03 GO:0080090 regulation of primary metabolic process
3.43 7.92e-03 GO:0007088 regulation of mitosis
3.43 7.92e-03 GO:0051783 regulation of nuclear division
3.92 8.74e-03 GO:0006406 mRNA export from nucleus
2.74 9.32e-03 GO:0031396 regulation of protein ubiquitination
1.66 1.09e-02 GO:0033554 cellular response to stress
3.35 1.14e-02 GO:0000236 mitotic prometaphase
1.26 1.30e-02 GO:0019222 regulation of metabolic process
1.56 1.39e-02 GO:0051246 regulation of protein metabolic process
1.57 1.42e-02 GO:0008104 protein localization
1.84 1.77e-02 GO:0034613 cellular protein localization
2.62 2.00e-02 GO:0000226 microtubule cytoskeleton organization
2.13 2.01e-02 GO:0006366 transcription from RNA polymerase II promoter
1.83 2.14e-02 GO:0070727 cellular macromolecule localization
2.37 2.14e-02 GO:0006605 protein targeting
1.53 2.42e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.39 2.56e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.28 2.58e-02 GO:0060255 regulation of macromolecule metabolic process
2.02 2.74e-02 GO:0007283 spermatogenesis
2.02 2.74e-02 GO:0048232 male gamete generation
1.62 2.90e-02 GO:0015031 protein transport
3.24 3.30e-02 GO:0022618 ribonucleoprotein complex assembly
1.57 3.78e-02 GO:0032774 RNA biosynthetic process
1.60 3.80e-02 GO:0006351 transcription, DNA-dependent
1.80 4.06e-02 GO:0006974 response to DNA damage stimulus
15.42 4.06e-02 GO:0046796 viral genome transport in host cell
2.86 4.32e-02 GO:0031398 positive regulation of protein ubiquitination
2.26 4.33e-02 GO:0071156 regulation of cell cycle arrest

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 7.49e-47 GO:0044424 intracellular part
1.29 3.54e-45 GO:0005622 intracellular
2.19 1.19e-37 GO:0044428 nuclear part
1.58 1.82e-34 GO:0005634 nucleus
1.37 1.38e-33 GO:0043231 intracellular membrane-bounded organelle
1.37 2.17e-33 GO:0043227 membrane-bounded organelle
1.32 4.92e-31 GO:0043229 intracellular organelle
1.32 1.07e-30 GO:0043226 organelle
1.55 2.37e-30 GO:0044446 intracellular organelle part
1.53 6.68e-29 GO:0044422 organelle part
2.08 7.71e-26 GO:0031981 nuclear lumen
1.35 7.46e-25 GO:0005737 cytoplasm
1.69 1.46e-24 GO:0032991 macromolecular complex
1.88 4.74e-22 GO:0070013 intracellular organelle lumen
1.85 7.60e-22 GO:0031974 membrane-enclosed lumen
1.86 1.76e-21 GO:0043233 organelle lumen
2.16 3.27e-20 GO:0005654 nucleoplasm
1.63 3.10e-16 GO:0043234 protein complex
2.38 3.04e-13 GO:0015630 microtubule cytoskeleton
2.53 4.73e-13 GO:0005694 chromosome
1.59 5.71e-13 GO:0043228 non-membrane-bounded organelle
1.59 5.71e-13 GO:0043232 intracellular non-membrane-bounded organelle
2.64 4.03e-12 GO:0044427 chromosomal part
3.71 1.80e-11 GO:0005819 spindle
3.22 1.05e-10 GO:0005635 nuclear envelope
2.37 1.16e-09 GO:0030529 ribonucleoprotein complex
1.30 1.42e-09 GO:0044444 cytoplasmic part
1.59 3.71e-09 GO:0005829 cytosol
4.91 2.38e-07 GO:0000922 spindle pole
2.82 4.31e-07 GO:0000785 chromatin
1.73 3.12e-06 GO:0044430 cytoskeletal part
1.91 3.36e-06 GO:0044451 nucleoplasm part
2.49 6.24e-06 GO:0005874 microtubule
1.07 9.29e-06 GO:0044464 cell part
1.07 9.59e-06 GO:0005623 cell
1.87 1.64e-05 GO:0031967 organelle envelope
5.54 3.25e-05 GO:0005876 spindle microtubule
1.84 3.57e-05 GO:0031975 envelope
3.04 5.00e-05 GO:0000775 chromosome, centromeric region
3.56 1.23e-04 GO:0016585 chromatin remodeling complex
2.19 2.11e-04 GO:0005815 microtubule organizing center
7.71 2.56e-04 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.94 3.18e-04 GO:0005730 nucleolus
3.53 5.14e-04 GO:0046930 pore complex
3.80 6.27e-04 GO:0005643 nuclear pore
1.48 7.50e-04 GO:0005856 cytoskeleton
2.40 8.79e-04 GO:0016604 nuclear body
3.33 1.31e-03 GO:0000776 kinetochore
2.54 2.18e-03 GO:0044454 nuclear chromosome part
4.07 2.19e-03 GO:0034708 methyltransferase complex
4.07 2.19e-03 GO:0035097 histone methyltransferase complex
3.63 2.43e-03 GO:0034399 nuclear periphery
3.73 3.30e-03 GO:0016363 nuclear matrix
2.83 3.88e-03 GO:0016607 nuclear speck
2.63 5.76e-03 GO:0031965 nuclear membrane
2.28 6.96e-03 GO:0000228 nuclear chromosome
1.42 7.34e-03 GO:0012505 endomembrane system
2.65 7.54e-03 GO:0005681 spliceosomal complex
4.35 1.16e-02 GO:0000118 histone deacetylase complex
2.55 1.38e-02 GO:0000151 ubiquitin ligase complex
2.18 1.60e-02 GO:0005813 centrosome
7.71 2.18e-02 GO:0010494 stress granule
3.01 2.92e-02 GO:0000790 nuclear chromatin
12.34 3.75e-02 GO:0071817 MMXD complex
2.44 4.06e-02 GO:0000793 condensed chromosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.43 4.18e-30 GO:0005515 protein binding
2.40 5.44e-17 GO:0003723 RNA binding
1.17 1.18e-15 GO:0005488 binding
1.52 5.93e-08 GO:0000166 nucleotide binding
1.40 2.70e-07 GO:0003676 nucleic acid binding
3.96 9.44e-05 GO:0042393 histone binding
2.48 1.60e-04 GO:0019787 small conjugating protein ligase activity
2.29 1.87e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.36 2.00e-04 GO:0016881 acid-amino acid ligase activity
2.00 2.70e-04 GO:0016874 ligase activity
2.49 3.12e-04 GO:0004842 ubiquitin-protein ligase activity
1.41 1.47e-03 GO:0017076 purine nucleotide binding
1.42 1.49e-03 GO:0035639 purine ribonucleoside triphosphate binding
2.49 1.97e-03 GO:0003682 chromatin binding
1.41 2.52e-03 GO:0032553 ribonucleotide binding
1.41 2.52e-03 GO:0032555 purine ribonucleotide binding
1.21 3.29e-03 GO:0003824 catalytic activity
1.57 4.78e-02 GO:0017111 nucleoside-triphosphatase activity