Motif ID: NFATC1..3.p2

Z-value: 1.426


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC3chr16_+_68119350-0.282.0e-05Click!
NFATC1chr18_+_771559270.144.4e-02Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_238322840 46.223 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr2_-_238322770 44.200 COL6A3
collagen, type VI, alpha 3
chr2_+_189839132 43.950 COL3A1
collagen, type III, alpha 1
chr2_-_238322815 36.100 COL6A3
collagen, type VI, alpha 3
chr2_+_189839078 34.846 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189839113 33.063 COL3A1
collagen, type III, alpha 1
chr12_-_91573264 27.767 NM_133503
DCN
decorin
chr12_+_13349720 21.734 EMP1
epithelial membrane protein 1
chr12_+_13349601 21.414 NM_001423
EMP1
epithelial membrane protein 1
chr2_-_216259197 19.664 FN1
fibronectin 1
chr7_+_23286384 17.397 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286386 17.255 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286390 17.240 GPNMB
glycoprotein (transmembrane) nmb
chr12_-_15038724 15.951 NM_000900
NM_001190839
MGP

matrix Gla protein

chr17_-_15164043 15.921 NM_153322
PMP22
peripheral myelin protein 22
chr1_-_150780705 14.013 NM_000396
CTSK
cathepsin K
chr3_-_195310985 13.867 NM_001647
APOD
apolipoprotein D
chr6_-_169653922 13.595 THBS2
thrombospondin 2
chr12_-_9268513 13.379 A2M
alpha-2-macroglobulin
chr7_+_116164838 13.341 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr1_+_162602308 13.024 DDR2
discoidin domain receptor tyrosine kinase 2
chr1_+_162602198 12.963 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr6_-_169654047 12.904 NM_003247
THBS2
thrombospondin 2
chr22_+_33196801 12.118 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr13_+_111134933 11.565 COL4A2
collagen, type IV, alpha 2
chr7_+_23286277 11.347 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr1_+_86046434 11.245 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_42811959 11.240 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr1_-_203320249 11.134


chr6_-_134639195 11.068 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_94024201 10.801 COL1A2
collagen, type I, alpha 2
chr3_-_195310770 10.557 APOD
apolipoprotein D
chr6_-_134495944 10.453 SGK1
serum/glucocorticoid regulated kinase 1
chr18_-_53068755 10.298 TCF4
transcription factor 4
chr3_+_119316694 10.296 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr12_-_9268475 10.119 A2M
alpha-2-macroglobulin
chr3_-_123411185 10.050 MYLK
myosin light chain kinase
chr1_-_203320287 9.987 NM_002023
FMOD
fibromodulin
chr12_-_9268522 9.914 NM_000014
A2M
alpha-2-macroglobulin
chr6_+_32407618 9.838 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr1_-_203320185 9.783 FMOD
fibromodulin
chr7_+_23286420 9.776 GPNMB
glycoprotein (transmembrane) nmb
chr1_+_226016428 9.717 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr2_-_216241321 9.303 FN1
fibronectin 1
chr4_+_169418167 9.119 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr1_+_101185195 9.020 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr6_-_134496006 8.880 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_93551015 8.684 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr12_-_9268440 8.651 A2M
alpha-2-macroglobulin
chr12_-_91505215 8.130 LUM
lumican
chr12_+_12938540 8.102 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr3_+_159557745 7.728 SCHIP1
schwannomin interacting protein 1
chr4_-_71532206 7.706 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr9_-_95298251 7.594 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_+_158979681 7.478 NM_001206567
NM_005531
IFI16

interferon, gamma-inducible protein 16

chr14_+_94577078 7.355 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr7_-_64023444 7.323


chr4_-_71532341 7.262 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr22_+_38071612 7.259 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr2_-_89165652 7.224


chr8_-_82395401 7.201 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr5_-_43412417 7.028 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr14_+_95078713 6.973 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_91505541 6.779 NM_002345
LUM
lumican
chr3_-_93692898 6.757 NM_000313
PROS1
protein S (alpha)
chr3_+_69812961 6.709 NM_006722
MITF
microphthalmia-associated transcription factor
chr4_+_88896868 6.660 SPP1
secreted phosphoprotein 1
chr9_+_706744 6.439 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_88896899 6.433 SPP1
secreted phosphoprotein 1
chrX_-_13835313 6.362 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr4_-_100242487 6.362 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr9_+_75766777 6.352 NM_000700
ANXA1
annexin A1
chr8_-_95274520 6.248 GEM
GTP binding protein overexpressed in skeletal muscle
chr8_-_95274540 6.166 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr12_+_119616594 6.157 NM_014365
HSPB8
heat shock 22kDa protein 8
chr3_-_149095413 6.155 TM4SF1
transmembrane 4 L six family member 1
chr8_-_82359620 6.118 NM_002677
PMP2
peripheral myelin protein 2
chr4_+_88896838 5.924 SPP1
secreted phosphoprotein 1
chr6_-_31981049 5.873 NM_032470
TNXB
tenascin XB
chr3_-_195306274 5.853 APOD
apolipoprotein D
chr13_-_38172862 5.834 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr3_+_45067750 5.755 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr3_-_149095517 5.733 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr1_-_57045235 5.730 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr16_-_65155881 5.726 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr10_-_90712510 5.644 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_149095333 5.615 TM4SF1
transmembrane 4 L six family member 1
chr2_-_190044330 5.613 NM_000393
COL5A2
collagen, type V, alpha 2
chrX_-_13835187 5.567 GPM6B
glycoprotein M6B
chr22_-_38380538 5.567 NM_006941
SOX10
SRY (sex determining region Y)-box 10
chr22_-_19512859 5.544 NM_001130861
NM_003277
CLDN5

claudin 5

chr5_+_140739589 5.540 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr7_+_100199881 5.472 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr11_+_114167197 5.466 NNMT
nicotinamide N-methyltransferase
chrX_+_135229536 5.459 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr1_+_171154387 5.438 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chrX_-_13835012 5.381 GPM6B
glycoprotein M6B
chrX_+_135251454 5.338 NM_001159704
FHL1
four and a half LIM domains 1
chr3_-_149095458 5.327 TM4SF1
transmembrane 4 L six family member 1
chr15_+_74466024 5.228 NM_005545
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr17_+_1665281 5.158 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_+_41281081 5.045 NM_001202553
MIA
melanoma inhibitory activity
chr12_-_91576805 4.992 NM_001920
DCN
decorin
chr10_-_79789290 4.913 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chrX_+_100805415 4.787 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr12_-_91576579 4.753 DCN
decorin
chr4_+_71248794 4.744 NM_006685
SMR3B
submaxillary gland androgen regulated protein 3B
chr7_-_100860991 4.649 NM_001084
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_-_8693391 4.643 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr14_-_107131217 4.641 IGHA1
immunoglobulin heavy constant alpha 1
chr6_-_131384387 4.615 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chr14_-_106573348 4.614 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chrX_+_103031753 4.547 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr5_+_34684611 4.546 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr18_-_52988916 4.539 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr5_+_140729723 4.511 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr4_-_76928601 4.511 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr5_+_140868721 4.490 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr19_+_16222706 4.430 RAB8A
RAB8A, member RAS oncogene family
chr1_+_159175048 4.428 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr12_-_50677238 4.425 NM_001113546
NM_016357
LIMA1

LIM domain and actin binding 1

chr3_+_361365 4.424 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr19_+_41281281 4.400 NM_006533
MIA
melanoma inhibitory activity
chr20_+_19915716 4.369 RIN2
Ras and Rab interactor 2
chr14_-_92413738 4.353 FBLN5
fibulin 5
chr9_-_35689799 4.344 TPM2
tropomyosin 2 (beta)
chr11_+_57365026 4.343 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_-_8892909 4.343 ST5
suppression of tumorigenicity 5
chr8_-_49833823 4.313 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr20_+_19867075 4.293 NM_001242581
RIN2
Ras and Rab interactor 2
chr10_+_17851342 4.286 NM_002438
MRC1
mannose receptor, C type 1
chrX_+_103031797 4.285 PLP1
proteolipid protein 1
chr4_+_88896801 4.244 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr16_+_1584161 4.224 NM_024600
TMEM204
transmembrane protein 204
chr4_+_74269971 4.206 NM_000477
ALB
albumin
chr9_-_13279562 4.192 MPDZ
multiple PDZ domain protein
chr4_+_175204827 4.188 NM_001040157
CEP44
centrosomal protein 44kDa
chr21_-_28339405 4.184 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr4_+_175205044 4.172 NM_001145314
CEP44
centrosomal protein 44kDa
chr3_-_137893718 4.151 DBR1
debranching enzyme homolog 1 (S. cerevisiae)
chr11_-_65382701 4.125 MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr9_-_35689902 4.121 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr19_+_37998041 4.119 ZNF793
zinc finger protein 793
chr1_-_169599349 4.119 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr11_+_308106 4.118 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr3_+_186560462 4.117 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr17_+_32582295 4.078 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr6_-_112575880 4.062 LAMA4
laminin, alpha 4
chr1_-_163113938 4.045 RGS5
regulator of G-protein signaling 5
chr14_-_106926393 4.041 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_27301693 4.028 EMILIN1
elastin microfibril interfacer 1
chr5_-_77844975 3.980 LHFPL2
lipoma HMGIC fusion partner-like 2
chr3_-_93692592 3.964 PROS1
protein S (alpha)
chr9_+_75766794 3.963 ANXA1
annexin A1
chr10_-_7682741 3.947 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr3_+_186560478 3.945 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr15_-_45480160 3.934 SHF
Src homology 2 domain containing F
chr3_-_183273407 3.931 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_+_99797632 3.925 MRPL30
mitochondrial ribosomal protein L30
chr1_-_94702916 3.911 ARHGAP29
Rho GTPase activating protein 29
chr1_+_203595929 3.853 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr12_+_54422193 3.848 NM_004503
HOXC6
homeobox C6
chr14_-_106746056 3.842


chr1_-_32169555 3.817 COL16A1
collagen, type XVI, alpha 1
chr11_-_10590078 3.801 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chrX_+_152760346 3.795 NM_001711
BGN
biglycan
chr5_-_146833150 3.794 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chrX_+_152760452 3.782 BGN
biglycan
chr6_+_116692098 3.759 NM_013352
DSE
dermatan sulfate epimerase
chr1_-_32169619 3.745 NM_001856
COL16A1
collagen, type XVI, alpha 1
chr19_+_41509825 3.699 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr22_-_38379868 3.676 SOX10
SRY (sex determining region Y)-box 10
chr17_-_40575117 3.673 NM_012232
PTRF
polymerase I and transcript release factor
chr4_+_124317884 3.662 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr6_-_112575766 3.657 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr17_-_48262900 3.646 COL1A1
collagen, type I, alpha 1
chr8_+_17433941 3.588 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr14_-_69259654 3.583 ZFP36L1
zinc finger protein 36, C3H type-like 1
chr12_+_69742140 3.557 LYZ
lysozyme
chr9_-_95166827 3.536 NM_014057
NM_033014
OGN

osteoglycin

chr12_-_7245048 3.535 C1R
complement component 1, r subcomponent
chr1_+_99127146 3.497 NM_015976
NM_152238
SNX7

sorting nexin 7

chr17_-_56160564 3.494


chr6_-_46825942 3.488 GPR116
G protein-coupled receptor 116
chr14_+_55595966 3.468 LGALS3
lectin, galactoside-binding, soluble, 3
chr13_-_45150391 3.443 TSC22D1
TSC22 domain family, member 1
chr2_+_99797536 3.431 NM_145212
MRPL30
mitochondrial ribosomal protein L30
chr9_-_129884998 3.426 NM_012098
ANGPTL2
angiopoietin-like 2
chr1_-_68697997 3.426 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr16_+_84853585 3.416 NM_031476
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr6_-_131384321 3.412 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_-_3306586 3.405 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr6_+_101846668 3.366 GRIK2
glutamate receptor, ionotropic, kainate 2
chr2_-_97405799 3.354 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr6_-_32013806 3.353 NM_032470
TNXB
tenascin XB
chr5_+_140810181 3.344 PCDHGA12
protocadherin gamma subfamily A, 12
chr6_-_46922533 3.344 NM_015234
GPR116
G protein-coupled receptor 116
chr1_-_94703252 3.340 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr2_-_97405775 3.333 LMAN2L
lectin, mannose-binding 2-like
chr2_-_56151273 3.320 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 1.98e-11 GO:0009611 response to wounding
1.93 2.43e-10 GO:0007155 cell adhesion
1.93 2.43e-10 GO:0022610 biological adhesion
1.64 2.66e-08 GO:0002376 immune system process
2.50 5.01e-08 GO:0030334 regulation of cell migration
2.40 7.28e-08 GO:0051270 regulation of cellular component movement
1.22 7.72e-08 GO:0050896 response to stimulus
2.47 8.66e-08 GO:2000145 regulation of cell motility
2.37 1.79e-07 GO:0040012 regulation of locomotion
1.80 1.88e-07 GO:0006955 immune response
1.42 2.43e-07 GO:0042221 response to chemical stimulus
1.18 2.47e-07 GO:0065007 biological regulation
1.33 2.53e-07 GO:0007165 signal transduction
1.31 3.35e-07 GO:0023052 signaling
1.40 6.29e-07 GO:0006950 response to stress
1.18 1.41e-06 GO:0050789 regulation of biological process
1.86 2.17e-06 GO:0042060 wound healing
1.27 2.20e-06 GO:0051716 cellular response to stimulus
2.75 3.67e-06 GO:0040017 positive regulation of locomotion
2.23 7.91e-06 GO:0006954 inflammatory response
1.69 9.13e-06 GO:0006952 defense response
1.90 1.03e-05 GO:0001775 cell activation
1.91 1.17e-05 GO:0007596 blood coagulation
1.91 1.17e-05 GO:0050817 coagulation
2.71 1.53e-05 GO:0030335 positive regulation of cell migration
2.71 1.53e-05 GO:2000147 positive regulation of cell motility
1.89 1.63e-05 GO:0007599 hemostasis
1.18 1.95e-05 GO:0050794 regulation of cellular process
1.22 1.99e-05 GO:0032501 multicellular organismal process
1.61 3.46e-05 GO:0042127 regulation of cell proliferation
1.51 5.17e-05 GO:0010033 response to organic substance
1.58 1.02e-04 GO:0032879 regulation of localization
2.53 1.14e-04 GO:0051272 positive regulation of cellular component movement
1.45 1.21e-04 GO:0009653 anatomical structure morphogenesis
2.24 1.52e-04 GO:0030168 platelet activation
1.40 1.65e-04 GO:0007166 cell surface receptor linked signaling pathway
1.63 1.77e-04 GO:0048584 positive regulation of response to stimulus
1.39 2.17e-04 GO:0048583 regulation of response to stimulus
1.25 4.40e-04 GO:0032502 developmental process
1.56 4.57e-04 GO:0070887 cellular response to chemical stimulus
1.37 5.39e-04 GO:0048513 organ development
1.27 6.74e-04 GO:0048856 anatomical structure development
1.72 9.29e-04 GO:0050878 regulation of body fluid levels
2.45 9.30e-04 GO:0050900 leukocyte migration
2.05 1.20e-03 GO:0048545 response to steroid hormone stimulus
1.28 1.52e-03 GO:0048731 system development
2.13 2.03e-03 GO:0032101 regulation of response to external stimulus
1.28 2.91e-03 GO:0048518 positive regulation of biological process
1.53 2.97e-03 GO:0051704 multi-organism process
2.02 3.22e-03 GO:0001568 blood vessel development
1.60 5.00e-03 GO:0002682 regulation of immune system process
1.64 5.43e-03 GO:0009725 response to hormone stimulus
1.24 5.67e-03 GO:0007275 multicellular organismal development
1.95 5.82e-03 GO:0001944 vasculature development
2.95 6.95e-03 GO:0002576 platelet degranulation
1.74 8.80e-03 GO:0050776 regulation of immune response
2.00 9.64e-03 GO:0050865 regulation of cell activation
1.41 9.76e-03 GO:0051239 regulation of multicellular organismal process
2.68 1.06e-02 GO:0030198 extracellular matrix organization
2.04 1.75e-02 GO:0051249 regulation of lymphocyte activation
1.99 1.77e-02 GO:0002694 regulation of leukocyte activation
2.49 1.89e-02 GO:0007565 female pregnancy
1.28 1.94e-02 GO:0048522 positive regulation of cellular process
1.88 1.97e-02 GO:0016337 cell-cell adhesion
1.64 2.76e-02 GO:0008284 positive regulation of cell proliferation
1.71 3.03e-02 GO:0008285 negative regulation of cell proliferation
2.31 3.23e-02 GO:0007156 homophilic cell adhesion
2.15 3.28e-02 GO:0051251 positive regulation of lymphocyte activation
2.67 4.26e-02 GO:0051271 negative regulation of cellular component movement
1.42 4.38e-02 GO:0010646 regulation of cell communication
1.54 4.69e-02 GO:0009719 response to endogenous stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.27 1.27e-22 GO:0005615 extracellular space
2.07 7.39e-22 GO:0044421 extracellular region part
1.69 9.65e-21 GO:0005576 extracellular region
1.38 2.11e-06 GO:0044459 plasma membrane part
1.98 6.11e-06 GO:0031012 extracellular matrix
2.04 1.61e-05 GO:0005578 proteinaceous extracellular matrix
3.71 2.08e-05 GO:0031091 platelet alpha granule
1.48 2.90e-05 GO:0031226 intrinsic to plasma membrane
1.48 3.47e-05 GO:0005887 integral to plasma membrane
4.20 2.67e-04 GO:0005581 collagen
1.21 4.99e-04 GO:0005886 plasma membrane
3.64 5.27e-04 GO:0031093 platelet alpha granule lumen
3.49 5.43e-04 GO:0031983 vesicle lumen
3.57 7.41e-04 GO:0034774 secretory granule lumen
1.20 8.70e-04 GO:0071944 cell periphery
3.42 1.42e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.01 5.54e-03 GO:0030141 stored secretory granule
5.75 6.82e-03 GO:0042613 MHC class II protein complex
6.41 9.14e-03 GO:0005583 fibrillar collagen
1.89 1.35e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.71 2.56e-09 GO:0005102 receptor binding
2.44 4.23e-06 GO:0005125 cytokine activity
2.82 7.87e-05 GO:0019838 growth factor binding
2.29 2.38e-04 GO:0005126 cytokine receptor binding
1.82 8.71e-04 GO:0030246 carbohydrate binding
6.04 2.02e-03 GO:0008329 pattern recognition receptor activity
3.36 3.49e-03 GO:0003707 steroid hormone receptor activity
2.22 3.85e-03 GO:0001871 pattern binding
2.22 3.85e-03 GO:0030247 polysaccharide binding
2.26 4.56e-03 GO:0005539 glycosaminoglycan binding
3.17 8.34e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.12 1.12e-02 GO:0005515 protein binding
3.53 1.28e-02 GO:0003823 antigen binding
3.28 1.70e-02 GO:0008009 chemokine activity
1.26 4.01e-02 GO:0004871 signal transducer activity
1.26 4.01e-02 GO:0060089 molecular transducer activity