Motif ID: NKX2-2,8.p2

Z-value: 1.776


Transcription factors associated with NKX2-2,8.p2:

Gene SymbolEntrez IDGene Name
NKX2-2 4821 NK2 homeobox 2
NKX2-8 26257 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-8chr14_-_37051785-0.502.4e-15Click!
NKX2-2chr20_-_21494663-0.274.6e-05Click!


Activity profile for motif NKX2-2,8.p2.

activity profile for motif NKX2-2,8.p2


Sorted Z-values histogram for motif NKX2-2,8.p2

Sorted Z-values for motif NKX2-2,8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2,8.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_225370687 86.564 CUL3
cullin 3
chr15_+_80390757 65.073 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chr2_-_225378320 58.261 CUL3
cullin 3
chr3_-_121379757 52.551 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379701 50.642 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_-_98336445 47.849 TM9SF3
transmembrane 9 superfamily member 3
chr5_+_115898218 39.851


chr3_+_152017193 38.387 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr2_+_228356287 37.197 AGFG1
ArfGAP with FG repeats 1
chr11_-_47510518 35.583 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr19_+_49838673 33.266 NM_001040031
NM_001774
CD37

CD37 molecule

chr12_+_69004614 32.603 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr19_+_49838700 31.885 CD37
CD37 molecule
chr5_-_137848517 31.456 ETF1
eukaryotic translation termination factor 1
chr12_+_64803741 31.451 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr17_+_26794838 30.306


chr18_+_29671817 29.903 NM_016271
RNF138
ring finger protein 138
chr9_+_131447364 29.799 NM_001248000
SET
SET nuclear oncogene
chr5_+_162930230 28.506 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr5_-_98262217 28.257 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr14_-_75600111 28.166 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr19_+_49838646 27.913 CD37
CD37 molecule
chr8_+_26150731 26.384 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr16_+_56815703 25.998 NM_001242795
NUP93
nucleoporin 93kDa
chr10_+_112344076 25.769 SMC3
structural maintenance of chromosomes 3
chr14_+_67831484 25.423 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr19_-_18433933 24.787 NM_001252129
NM_012321
LSM4

LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr13_-_41556188 24.630 ELF1
E74-like factor 1 (ets domain transcription factor)
chrX_+_123234462 24.455 STAG2
stromal antigen 2
chr2_-_20512016 24.291 PUM2
pumilio homolog 2 (Drosophila)
chr1_+_198608136 24.192 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr7_+_2394525 23.986 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr14_-_100841656 23.965 WARS
tryptophanyl-tRNA synthetase
chr12_-_46633551 23.650 SLC38A1
solute carrier family 38, member 1
chr4_-_83347222 23.588 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr1_+_53480616 23.472 SCP2
sterol carrier protein 2
chr7_+_112092112 23.274 NM_001197079
IFRD1
interferon-related developmental regulator 1
chrX_-_70474402 23.170 NM_001171163
NM_005096
ZMYM3

zinc finger, MYM-type 3

chr1_+_53480573 22.791 NM_001007099
NM_001007100
NM_001007250
SCP2


sterol carrier protein 2


chr7_+_115863004 22.717 NM_152829
TES
testis derived transcript (3 LIM domains)
chr1_+_171481164 22.407 PRRC2C
proline-rich coiled-coil 2C
chr1_+_167298280 22.014 NM_001198783
POU2F1
POU class 2 homeobox 1
chr19_+_49838734 21.985 CD37
CD37 molecule
chr1_-_75199091 21.463 NM_001130042
NM_001130043
NM_001134759
NM_001889
CRYZ



crystallin, zeta (quinone reductase)



chr14_+_39649711 21.326 PNN
pinin, desmosome associated protein
chr5_+_6746100 21.216 NM_001171806
PAPD7
PAP associated domain containing 7
chr1_+_198608244 21.118 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608216 20.823 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_-_75970566 20.413 TMEM30A
transmembrane protein 30A
chr20_-_36152952 20.386 NM_001167823
BLCAP
bladder cancer associated protein
chr21_+_30400229 20.140 USP16
ubiquitin specific peptidase 16
chr3_+_63953419 19.877 NM_001128149
ATXN7
ataxin 7
chr8_+_17829848 19.713 PCM1
pericentriolar material 1
chr3_-_56698073 19.309 NM_015224
FAM208A
family with sequence similarity 208, member A
chr7_+_2394428 19.266 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr3_-_196911001 19.057 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr2_-_151344145 18.932 NM_005168
RND3
Rho family GTPase 3
chr8_+_17822093 18.847 PCM1
pericentriolar material 1
chr15_-_60690115 18.334 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr1_-_225616556 18.126 NM_194442
LBR
lamin B receptor
chr7_+_2394498 18.065 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr17_-_1248346 17.893 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr12_+_25205180 17.832 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr1_-_207095198 17.805 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_29641094 17.775 NM_006495
EVI2B
ecotropic viral integration site 2B
chr18_+_33234532 17.732 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr1_-_21377452 17.707 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_38207247 17.662 OXSR1
oxidative-stress responsive 1
chr3_-_15839674 17.529 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr1_+_236558715 17.425 NM_080738
EDARADD
EDAR-associated death domain
chr2_+_183582667 17.210 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_-_20801427 17.189 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr14_-_100841793 17.090 WARS
tryptophanyl-tRNA synthetase
chr2_+_85804613 16.974 NM_003761
VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr12_+_121132677 16.779


chrX_+_123095598 16.736 STAG2
stromal antigen 2
chrX_+_11777734 16.681 NM_006800
MSL3
male-specific lethal 3 homolog (Drosophila)
chr12_-_58240746 16.528 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr7_+_2394508 16.366 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr15_-_55563091 16.250 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chrX_+_107288199 16.158 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr1_+_84630014 16.138 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr10_-_121296044 16.036 NM_002925
RGS10
regulator of G-protein signaling 10
chr1_+_244214552 16.003 NM_205768
ZNF238
zinc finger protein 238
chr1_+_215178884 15.941 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr5_-_86703927 15.748 CCNH
cyclin H
chr4_+_146019155 15.696 NM_001040876
NM_002940
ABCE1

ATP-binding cassette, sub-family E (OABP), member 1

chr10_-_98325100 15.541 TM9SF3
transmembrane 9 superfamily member 3
chr13_-_46756326 15.478 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr9_+_112887780 15.132 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr12_-_102512277 15.122 NM_024057
NUP37
nucleoporin 37kDa
chr4_-_84035908 15.003 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr17_-_29641087 14.833 EVI2B
ecotropic viral integration site 2B
chr4_-_140060601 14.757 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr6_-_150067631 14.651 NM_198887
NUP43
nucleoporin 43kDa
chr10_+_28878666 14.335 WAC
WW domain containing adaptor with coiled-coil
chr12_+_25205488 14.208 LRMP
lymphoid-restricted membrane protein
chr1_+_84630374 14.150 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_71532206 13.873 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr9_+_91926109 13.858 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr12_-_58240493 13.657 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr4_-_84035888 13.541 PLAC8
placenta-specific 8
chr8_+_66582107 13.095 NM_001145838
MTFR1
mitochondrial fission regulator 1
chrX_+_108779009 13.022 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr18_+_32558207 12.703 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_+_155484131 12.544 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr3_-_119582422 12.362 GSK3B
glycogen synthase kinase 3 beta
chr15_-_56209305 12.338 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_+_11665394 12.106 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr20_+_57226287 11.806 NM_001001433
NM_001134772
NM_001134773
NM_001204868
NM_003763
STX16-NPEPL1
STX16




STX16-NPEPL1 readthrough (non-protein coding)
syntaxin 16




chr6_-_86351156 11.734 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr7_-_138794393 11.663 NM_020119
NM_024625
ZC3HAV1

zinc finger CCCH-type, antiviral 1

chr1_-_41627045 11.310 NM_001031694
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chrX_-_77225134 11.267 NM_001029891
PGAM4
phosphoglycerate mutase family member 4
chr13_+_52598678 11.148 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr6_+_49467670 10.966 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr14_-_21899866 10.851 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr14_+_102276125 10.695 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr12_+_93861265 10.692 NM_014050
NM_172177
MRPL42

mitochondrial ribosomal protein L42

chr10_-_65028825 10.659 NM_004241
JMJD1C
jumonji domain containing 1C
chr1_+_110560111 10.572 AHCYL1
adenosylhomocysteinase-like 1
chr13_-_41556360 10.543 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_+_244214576 10.438 ZNF238
zinc finger protein 238
chr3_+_100428393 10.435 TFG
TRK-fused gene
chr19_-_55767103 10.413 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr7_-_76829109 10.354 NM_006682
FGL2
fibrinogen-like 2
chr1_+_212475147 10.352 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr13_-_50367027 10.340 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr8_-_80993009 10.128 NM_001025252
TPD52
tumor protein D52
chr19_-_40337018 10.099 NM_001436
FBL
fibrillarin
chr12_+_28410132 10.096 NM_018318
CCDC91
coiled-coil domain containing 91
chr1_-_26393984 9.980 NM_032588
TRIM63
tripartite motif containing 63
chr10_+_91498724 9.886 KIF20B
kinesin family member 20B
chr16_-_46782104 9.840 NM_182493
MYLK3
myosin light chain kinase 3
chr6_+_26365397 9.748 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr3_+_183892569 9.696 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr1_-_226926875 9.558 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr14_+_89060729 9.505 NM_207662
ZC3H14
zinc finger CCCH-type containing 14
chr19_-_14889347 9.431 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr2_+_102508377 9.395 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_170655321 9.333 NM_003142
SSB
Sjogren syndrome antigen B (autoantigen La)
chr1_+_174844655 9.303 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr2_+_102508333 9.257 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_74088773 9.251 ANKRD17
ankyrin repeat domain 17
chr1_-_31538553 9.241 NM_001020658
NM_014676
PUM1

pumilio homolog 1 (Drosophila)

chr12_-_90049818 9.191 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr3_+_183892647 9.145 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr13_-_48987017 9.123 LPAR6
lysophosphatidic acid receptor 6
chr9_+_125132823 9.071 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_122159140 9.066 CLASP1
cytoplasmic linker associated protein 1
chr8_+_11665959 9.052 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr7_-_140179224 8.913 MKRN1
makorin ring finger protein 1
chr3_+_183892668 8.906 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr16_-_4854748 8.771 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr4_-_99851785 8.768 NM_001130679
NM_001968
EIF4E

eukaryotic translation initiation factor 4E

chr3_+_100428361 8.725 NM_001195478
TFG
TRK-fused gene
chr14_-_95608054 8.704 NM_030621
DICER1
dicer 1, ribonuclease type III
chr20_+_56964162 8.677 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr9_-_14086901 8.670 NFIB
nuclear factor I/B
chr3_+_158991035 8.657 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr1_+_62901974 8.654 NM_001017415
NM_001017416
USP1

ubiquitin specific peptidase 1

chr17_-_38721701 8.637 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr3_+_183892662 8.586 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_-_50616425 8.558 NM_001113547
LIMA1
LIM domain and actin binding 1
chr14_-_100841926 8.516 NM_004184
NM_213646
WARS

tryptophanyl-tRNA synthetase

chr1_-_246670518 8.472 SMYD3
SET and MYND domain containing 3
chr6_-_119252887 8.460 NM_017696
MCM9
minichromosome maintenance complex component 9
chr5_+_70944968 8.450 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_-_21377387 8.410 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr14_+_23789396 8.358 NM_004643
PABPN1
poly(A) binding protein, nuclear 1
chr11_-_77850633 8.351 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr2_-_37544165 8.266 NM_005813
PRKD3
protein kinase D3
chr6_+_32936400 8.263 NM_005104
BRD2
bromodomain containing 2
chr5_+_137673223 8.256 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr2_-_10942642 8.137 PDIA6
protein disulfide isomerase family A, member 6
chr7_+_872137 8.116 NM_001130965
SUN1
Sad1 and UNC84 domain containing 1
chr14_+_102276279 8.100 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr17_+_75316059 8.061 SEPT9
septin 9
chr2_+_201754049 8.011 NM_001136039
NM_001142355
NM_021824
NIF3L1


NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)


chr9_+_116263706 7.945 NM_130795
RGS3
regulator of G-protein signaling 3
chr1_+_236557643 7.937 NM_145861
EDARADD
EDAR-associated death domain
chr1_+_148560846 7.935 NM_173638
NBPF15
neuroblastoma breakpoint family, member 15
chr1_-_23886284 7.934 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_+_143886898 7.892 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr12_-_10021932 7.847 CLEC2B
C-type lectin domain family 2, member B
chr11_-_26743545 7.782 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr2_+_233709104 7.738 GIGYF2
GRB10 interacting GYF protein 2
chr11_-_77850687 7.694 NM_001007027
NM_024079
ALG8

asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)

chr5_-_150521200 7.666 NM_001193544
ANXA6
annexin A6
chr13_-_107220444 7.583 NM_018011
ARGLU1
arginine and glutamate rich 1
chr2_+_58273651 7.575 NM_001130480
NM_001130482
NM_001130483
NM_006296
NM_001130481
VRK2




vaccinia related kinase 2




chr11_-_57103324 7.564 NM_003146
SSRP1
structure specific recognition protein 1
chr12_-_49582800 7.492 NM_006009
TUBA1A
tubulin, alpha 1a
chr22_-_38881529 7.466 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr1_+_167298382 7.420 POU2F1
POU class 2 homeobox 1
chr3_+_88188261 7.399 NM_018293
ZNF654
zinc finger protein 654
chr12_-_54689536 7.360 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr13_+_98605928 7.285 NM_002271
IPO5
importin 5
chr3_-_113897849 7.272 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr5_+_102465256 7.063 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 5.30e-10 GO:0009987 cellular process
1.30 2.07e-06 GO:0065007 biological regulation
1.30 1.02e-05 GO:0050789 regulation of biological process
1.30 5.27e-05 GO:0050794 regulation of cellular process
1.60 1.32e-04 GO:0071842 cellular component organization at cellular level
1.56 2.97e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.77 3.61e-04 GO:0006996 organelle organization
1.31 5.75e-04 GO:0044237 cellular metabolic process
1.40 6.44e-04 GO:0044260 cellular macromolecule metabolic process
1.40 1.72e-03 GO:0051716 cellular response to stimulus
1.28 2.93e-03 GO:0044238 primary metabolic process
1.51 3.23e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 3.92e-03 GO:0034641 cellular nitrogen compound metabolic process
1.43 4.13e-03 GO:0071840 cellular component organization or biogenesis
1.44 4.85e-03 GO:0016043 cellular component organization
1.33 5.06e-03 GO:0043170 macromolecule metabolic process
1.44 5.37e-03 GO:0006807 nitrogen compound metabolic process
1.25 6.17e-03 GO:0008152 metabolic process
1.26 2.07e-02 GO:0050896 response to stimulus
2.49 2.31e-02 GO:0044419 interspecies interaction between organisms
1.52 2.85e-02 GO:0090304 nucleic acid metabolic process
1.39 3.07e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 6.10e-08 GO:0044424 intracellular part
1.27 3.58e-07 GO:0005737 cytoplasm
1.17 2.34e-06 GO:0005622 intracellular
1.21 1.07e-05 GO:0043226 organelle
1.21 1.38e-05 GO:0043229 intracellular organelle
5.83 7.58e-05 GO:0005643 nuclear pore
1.21 1.35e-04 GO:0043227 membrane-bounded organelle
1.21 1.85e-04 GO:0043231 intracellular membrane-bounded organelle
1.31 3.32e-04 GO:0005634 nucleus
4.85 6.85e-04 GO:0046930 pore complex
1.53 2.52e-03 GO:0044428 nuclear part
1.37 6.92e-03 GO:0032991 macromolecular complex
1.26 7.87e-03 GO:0044422 organelle part
2.63 2.31e-02 GO:0005635 nuclear envelope
1.39 3.55e-02 GO:0043228 non-membrane-bounded organelle
1.39 3.55e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.24 4.05e-02 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 1.10e-08 GO:0005515 protein binding
1.15 2.94e-05 GO:0005488 binding
1.95 2.93e-03 GO:0003723 RNA binding