Motif ID: PDX1.p2

Z-value: 0.473


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PDX1chr13_+_284941360.558.5e-19Click!


Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_176733413 11.963 GPM6A
glycoprotein M6A
chr1_+_159175048 7.614 NM_001122951
DARC
Duffy blood group, chemokine receptor
chrX_+_110366304 5.893 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr4_-_176733901 4.530 GPM6A
glycoprotein M6A
chr17_+_38119225 3.767 NM_178171
GSDMA
gasdermin A
chr7_-_44228880 3.680 NM_000162
GCK
glucokinase (hexokinase 4)
chr17_+_7482980 3.627 CD68
CD68 molecule
chr17_+_7482938 3.616 CD68
CD68 molecule
chr1_+_63063186 3.541 NM_014495
ANGPTL3
angiopoietin-like 3
chr4_+_86396251 3.360 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr8_-_27115935 3.131 STMN4
stathmin-like 4
chr6_-_133035180 3.063 NM_004666
VNN1
vanin 1
chr16_+_70557688 3.022 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr3_+_35722428 2.895 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_100238063 2.813 TMEM45A
transmembrane protein 45A
chr2_-_166060552 2.753 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr3_+_115342150 2.648 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr8_-_17579729 2.330 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr6_-_31107110 2.271 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr16_+_19078916 2.170 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr4_+_88720701 2.139 NM_004967
IBSP
integrin-binding sialoprotein
chr4_+_88896801 2.109 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr19_-_7766978 2.066 NM_001220500
NM_002002
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr12_-_54020081 2.016 NM_001130060
NM_001206682
NM_006856
ATF7


activating transcription factor 7


chr6_-_55740387 2.002 BMP5
bone morphogenetic protein 5
chr16_+_19078958 1.792 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr11_-_62457370 1.780 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr17_+_7482804 1.710 NM_001251
NM_001040059
CD68

CD68 molecule

chr14_+_101295409 1.696 MEG3
maternally expressed 3 (non-protein coding)
chr1_-_20250051 1.688 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr6_-_41254392 1.688 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr6_+_72922513 1.439 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr3_-_21792815 1.438 NM_024697
ZNF385D
zinc finger protein 385D
chr12_-_4488707 1.398 NM_020638
FGF23
fibroblast growth factor 23
chr6_+_33043702 1.379 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr17_+_7960201 1.345


chr1_+_163038934 1.343 NM_001113381
RGS4
regulator of G-protein signaling 4
chr3_+_46619075 1.333 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr12_-_91398744 1.270 EPYC
epiphycan
chr2_+_169921298 1.262 NM_005771
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_+_185463235 1.244 ZNF804A
zinc finger protein 804A
chr8_-_17580024 1.228 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr6_-_55740358 1.197 NM_021073
BMP5
bone morphogenetic protein 5
chr1_+_163038564 1.173 NM_005613
RGS4
regulator of G-protein signaling 4
chr3_+_52813936 1.097 NM_001166435
NM_001166436
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr9_+_82187469 1.062 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_158300517 1.037 NM_004288
CYTIP
cytohesin 1 interacting protein
chr17_-_39637351 1.014 NM_002280
KRT35
keratin 35
chr17_-_29641068 0.974 EVI2B
ecotropic viral integration site 2B
chr11_-_66445318 0.966 RBM4B
RNA binding motif protein 4B
chr1_+_36748164 0.927 THRAP3
thyroid hormone receptor associated protein 3
chr12_+_75784878 0.927 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr10_+_115310589 0.923 NM_001177660
HABP2
hyaluronan binding protein 2
chr6_-_62995852 0.907 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr19_-_14952688 0.887 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr6_-_46825942 0.799 GPR116
G protein-coupled receptor 116
chr1_+_101003692 0.789 NM_022049
GPR88
G protein-coupled receptor 88
chr1_+_92632608 0.785 NM_015237
KIAA1107
KIAA1107
chr9_+_82187599 0.782 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_-_20040612 0.761 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr10_-_62332666 0.754 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_167191808 0.742 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr16_+_19079220 0.737 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr12_+_4829751 0.729 NM_017417
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr8_-_17555158 0.724 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr7_+_93535819 0.715 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_10962673 0.705 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr4_+_187187342 0.701 F11
coagulation factor XI
chr2_+_169926084 0.682 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr3_-_114343791 0.681 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_140201221 0.680 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr4_+_113970784 0.671 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr6_+_25754926 0.654 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr4_+_74606222 0.632 NM_000584
IL8
interleukin 8
chr9_-_21228132 0.624 NM_021268
IFNA17
interferon, alpha 17
chr1_-_204135420 0.620 NM_000537
REN
renin
chr11_+_88911039 0.585 NM_000372
TYR
tyrosinase (oculocutaneous albinism IA)
chr16_+_8814567 0.580 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr12_-_103311380 0.554 NM_000277
PAH
phenylalanine hydroxylase
chr21_-_31538970 0.552 NM_012131
CLDN17
claudin 17
chr6_+_35310399 0.539 PPARD
peroxisome proliferator-activated receptor delta
chr4_-_10023094 0.538 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr5_-_75919051 0.533 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr1_+_186265404 0.530 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr6_+_131571298 0.523 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr14_+_70918873 0.522 NM_003813
ADAM21
ADAM metallopeptidase domain 21
chr7_-_113559048 0.520 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr1_-_16763887 0.509 NM_198546
SPATA21
spermatogenesis associated 21
chr12_+_119616594 0.503 NM_014365
HSPB8
heat shock 22kDa protein 8
chr6_+_72926144 0.503 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr4_+_78432905 0.475 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr7_+_156435670 0.463 NM_001184997
RNF32
ring finger protein 32
chr15_+_67841341 0.458 NM_001206804
MAP2K5
mitogen-activated protein kinase kinase 5
chr12_+_51318515 0.456 NM_014033
METTL7A
methyltransferase like 7A
chr1_-_161601251 0.449 NM_001244753
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr8_+_32579350 0.448 NM_001159996
NRG1
neuregulin 1
chr19_-_14785626 0.443 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr1_+_13911966 0.434 NM_001006624
NM_001006625
PDPN

podoplanin

chr3_+_151531860 0.421 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr11_+_28131830 0.417 METTL15
methyltransferase like 15
chr1_+_17906941 0.411 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_-_43423785 0.402 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr12_-_121454285 0.397 NM_022895
C12orf43
chromosome 12 open reading frame 43
chr17_-_29641087 0.394 EVI2B
ecotropic viral integration site 2B
chr3_+_148447966 0.392 NM_032049
AGTR1
angiotensin II receptor, type 1
chr3_+_52811601 0.390 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_38859976 0.383 NM_019016
KRT24
keratin 24
chr1_-_161519817 0.369 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr17_-_29641094 0.366 NM_006495
EVI2B
ecotropic viral integration site 2B
chr10_+_32856650 0.347 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr6_-_138539626 0.326 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr3_-_47933997 0.325 MAP4
microtubule-associated protein 4
chr5_-_16509106 0.325 NM_019000
FAM134B
family with sequence similarity 134, member B
chr1_-_186417855 0.314 NM_022576
PDC
phosducin
chr9_-_21239975 0.313 NM_002172
IFNA14
interferon, alpha 14
chr3_+_11178778 0.312 NM_001098213
HRH1
histamine receptor H1
chr11_-_104905849 0.285 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr4_+_71457974 0.283 NM_016519
AMBN
ameloblastin (enamel matrix protein)
chr5_+_140227356 0.283 NM_014005
NM_031857
PCDHA9

protocadherin alpha 9

chr12_-_91398757 0.281 NM_004950
EPYC
epiphycan
chr16_-_70557430 0.280 NM_001195139
NM_015386
COG4

component of oligomeric golgi complex 4

chr12_-_121454210 0.280 C12orf43
chromosome 12 open reading frame 43
chr4_+_74281884 0.272 ALB
albumin
chr4_-_46996423 0.262 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr7_+_129269916 0.252 NM_001040110
NRF1
nuclear respiratory factor 1
chr11_+_123986103 0.251 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chr5_+_140718353 0.249 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chrX_+_37639306 0.246 CYBB
cytochrome b-245, beta polypeptide
chr7_+_26400503 0.245 NM_001199837
SNX10
sorting nexin 10
chr10_+_70980058 0.237 NM_025130
HKDC1
hexokinase domain containing 1
chr16_+_29674282 0.232 NM_001030288
SPN
sialophorin
chr7_-_27166638 0.230 NM_153631
HOXA3
homeobox A3
chr6_-_143266283 0.209 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_44580857 0.196 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr16_+_28505920 0.193 NM_018690
APOBR
apolipoprotein B receptor
chr2_-_216259197 0.191 FN1
fibronectin 1
chr5_-_16738346 0.180 MYO10
myosin X
chr12_+_10460416 0.168 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr1_+_57320442 0.163 NM_000562
C8A
complement component 8, alpha polypeptide
chr6_-_134498973 0.158 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chrX_-_62780748 0.156 LOC92249
uncharacterized LOC92249
chr3_-_178969644 0.154 NM_171830
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_-_32731266 0.149 NM_001198858
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr1_+_84609941 0.149 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_108541544 0.146 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr18_+_616671 0.133 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr6_+_112375277 0.122 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr20_+_31037447 0.122


chr1_-_21605984 0.102 NM_001113347
ECE1
endothelin converting enzyme 1
chr12_+_4699243 0.098 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr5_+_54398473 0.098 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chrX_+_99899388 0.093 SRPX2
sushi-repeat containing protein, X-linked 2
chr17_-_7082654 0.081 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr7_+_80275967 0.077 CD36
CD36 molecule (thrombospondin receptor)
chrX_+_99899162 0.075 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr9_+_136501484 0.073 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr17_-_10372875 0.058 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr6_+_167704802 0.058 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chrX_+_49091926 0.057 NM_014008
CCDC22
coiled-coil domain containing 22
chr6_+_167536240 0.055 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr2_-_218808705 0.035 NM_022648
TNS1
tensin 1
chr3_-_114478117 0.033 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_+_140235594 0.033 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr7_-_87342569 0.008 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr15_+_48498497 0.004 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.15 3.19e-03 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.42 3.81e-05 GO:0005576 extracellular region
1.81 1.84e-04 GO:0071944 cell periphery
1.80 2.80e-04 GO:0005886 plasma membrane
2.20 5.30e-04 GO:0044459 plasma membrane part
3.10 2.42e-03 GO:0005615 extracellular space
2.65 7.51e-03 GO:0044421 extracellular region part
1.42 4.74e-02 GO:0044425 membrane part

Nothing significant found in function category.