Motif ID: PITX1..3.p2

Z-value: 2.316


Transcription factors associated with PITX1..3.p2:

Gene SymbolEntrez IDGene Name
PITX1 5307 paired-like homeodomain 1
PITX2 5308 paired-like homeodomain 2
PITX3 5309 paired-like homeodomain 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PITX2chr4_-_1115442060.235.5e-04Click!
PITX3chr10_-_104001229-0.082.2e-01Click!
PITX1chr5_-_1343695710.027.4e-01Click!


Activity profile for motif PITX1..3.p2.

activity profile for motif PITX1..3.p2


Sorted Z-values histogram for motif PITX1..3.p2

Sorted Z-values for motif PITX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_18798077 24.610


chr22_-_17680485 23.483 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr19_-_39826625 23.244 GMFG
glia maturation factor, gamma
chr22_-_17690778 22.095 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr19_-_39826676 22.033 NM_004877
GMFG
glia maturation factor, gamma
chr17_-_38821286 21.477 NM_152349
KRT222
keratin 222
chr3_+_127317271 17.961 MCM2
minichromosome maintenance complex component 2
chr1_-_150738292 17.908 NM_001199739
NM_004079
CTSS

cathepsin S

chr3_+_127317274 17.802 MCM2
minichromosome maintenance complex component 2
chr9_+_131217433 16.884 NM_153436
ODF2
outer dense fiber of sperm tails 2
chr3_-_141719188 16.801 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr3_+_127317212 16.294 NM_004526
MCM2
minichromosome maintenance complex component 2
chr1_-_150738255 16.143 CTSS
cathepsin S
chr16_+_29471206 16.040 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_+_73624328 15.768 LAT2
linker for activation of T cells family, member 2
chr20_+_55926144 15.722 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr7_+_73624347 15.603 LAT2
linker for activation of T cells family, member 2
chr22_-_42336222 14.995 NM_001110215
CENPM
centromere protein M
chr12_-_117537090 14.832 NM_001168325
NM_017899
TESC

tescalcin

chr16_+_30210548 14.711 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_-_118213321 14.413 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr1_+_114496498 14.301 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr16_+_50321822 14.271 NM_001114
ADCY7
adenylate cyclase 7
chr20_+_55926299 13.950 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr20_+_35807522 13.837 RPN2
ribophorin II
chr12_+_54892567 13.828 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr7_+_73624086 13.606 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr19_-_48744276 13.165 NM_001184900
CARD8
caspase recruitment domain family, member 8
chr19_+_8509594 13.151 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr1_-_153348057 13.073 NM_005621
S100A12
S100 calcium binding protein A12
chr19_-_10291056 12.963


chr16_+_88003623 12.748 NM_001173543
BANP
BTG3 associated nuclear protein
chr19_-_9731883 12.741 NM_152289
ZNF561
zinc finger protein 561
chr19_+_1071208 12.678 HMHA1
histocompatibility (minor) HA-1
chr2_-_96950421 12.429 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr11_-_73693883 12.185 NM_003355
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr20_+_35807430 12.168 NM_001135771
NM_002951
RPN2

ribophorin II

chr19_+_14491920 12.114 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr7_-_99699426 12.002 NM_005916
MCM7
minichromosome maintenance complex component 7
chr14_-_23285011 11.991 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_150738232 11.841 CTSS
cathepsin S
chr12_-_8043743 11.764 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr19_-_17932312 11.588 NM_005543
INSL3
insulin-like 3 (Leydig cell)
chr13_+_50069745 11.530 NM_001040443
PHF11
PHD finger protein 11
chr16_+_30483959 11.405 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr17_-_56358266 11.243 NM_000250
MPO
myeloperoxidase
chr4_+_2627158 11.204 NM_003704
FAM193A
family with sequence similarity 193, member A
chr16_-_18801624 11.014 NM_001019
NM_001030009
RPS15A

ribosomal protein S15a

chr19_+_41768368 10.830 NM_144732
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr5_+_132406080 10.723 HSPA4
heat shock 70kDa protein 4
chr16_+_30484049 10.696 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr17_-_34625628 10.583 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr20_-_32891075 10.302 NM_000687
AHCY
adenosylhomocysteinase
chr17_-_74483806 10.173 NM_001005498
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr4_+_1894508 10.136 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr20_+_31407696 10.115 NM_012325
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr11_-_73693820 9.938 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_+_6135650 9.876 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr19_+_860615 9.860 CFD
complement factor D (adipsin)
chr6_+_31598366 9.813 PRRC2A
proline-rich coiled-coil 2A
chr13_+_37574677 9.809 NM_181503
EXOSC8
exosome component 8
chr2_+_39005326 9.804 NM_024775
GEMIN6
gem (nuclear organelle) associated protein 6
chr17_-_34524054 9.602 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr22_+_32870699 9.374 NM_012179
FBXO7
F-box protein 7
chr22_-_17646176 9.370 NM_017829
CECR5
cat eye syndrome chromosome region, candidate 5
chr6_-_42016609 9.346 NM_001136017
NM_001136126
CCND3

cyclin D3

chr17_-_3599487 9.317 NM_001204519
NM_001204520
NM_002561
NM_175080
P2RX5-TAX1BP3
P2RX5



P2RX5-TAX1BP3 readthrough
purinergic receptor P2X, ligand-gated ion channel, 5



chr5_+_55062712 9.304 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr14_+_73957608 9.245 NM_024644
C14orf169
chromosome 14 open reading frame 169
chr13_+_50070096 9.171 PHF11
PHD finger protein 11
chr20_+_55926585 9.117 NM_001015885
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr22_-_42343079 9.027 NM_001002876
NM_024053
CENPM

centromere protein M

chr14_+_54863672 9.021 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr1_+_111772332 8.991 NM_001025199
CHI3L2
chitinase 3-like 2
chr12_+_54891539 8.977 NCKAP1L
NCK-associated protein 1-like
chr16_-_25026650 8.871 NM_001006634
NM_018054
ARHGAP17

Rho GTPase activating protein 17

chr2_-_197664335 8.858 NM_001206774
NM_012086
GTF3C3

general transcription factor IIIC, polypeptide 3, 102kDa

chr14_+_58906398 8.820 NM_001244193
KIAA0586
KIAA0586
chr6_-_150057659 8.808 NUP43
nucleoporin 43kDa
chr12_+_54891522 8.748 NCKAP1L
NCK-associated protein 1-like
chr22_-_24096551 8.650 NM_013378
VPREB3
pre-B lymphocyte 3
chrX_+_9431314 8.649 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr1_+_43162386 8.629 YBX1
Y box binding protein 1
chr12_+_54891491 8.523 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr12_-_46357949 8.503


chr3_-_52029957 8.490 NM_000992
RPL29
ribosomal protein L29
chr12_-_31945174 8.369 NM_001013699
H3F3C
H3 histone, family 3C
chr5_-_176433365 8.311 NM_016290
NM_001199297
NM_001199298
UIMC1


ubiquitin interaction motif containing 1


chr14_-_55650348 8.267 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chrX_+_48542159 8.110 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr6_-_31619481 8.092


chr14_-_23426356 8.061 HAUS4
HAUS augmin-like complex, subunit 4
chr17_-_61920256 8.011 SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr5_-_140013285 7.994 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr2_-_85637486 7.948 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr18_+_657674 7.861 TYMS
thymidylate synthetase
chr13_+_43597338 7.825 NM_013238
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr17_+_7210317 7.793 NM_001143760
EIF5A
eukaryotic translation initiation factor 5A
chr13_+_37574916 7.772 EXOSC8
exosome component 8
chr17_-_62097937 7.741 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr1_-_27952591 7.701 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr13_+_25670275 7.670 NM_030979
PABPC3
poly(A) binding protein, cytoplasmic 3
chr11_+_68367824 7.649 PPP6R3
protein phosphatase 6, regulatory subunit 3
chr5_+_132432880 7.609 HSPA4
heat shock 70kDa protein 4
chr14_-_23426265 7.544 NM_001166269
NM_001166270
NM_017815
HAUS4


HAUS augmin-like complex, subunit 4


chr11_-_615920 7.522 IRF7
interferon regulatory factor 7
chr6_+_34204928 7.479 HMGA1
high mobility group AT-hook 1
chr17_+_41158741 7.420 NM_005533
IFI35
interferon-induced protein 35
chr18_+_657633 7.410 TYMS
thymidylate synthetase
chr20_+_35807695 7.401 RPN2
ribophorin II
chr11_+_308106 7.386 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr2_+_68961912 7.381 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr11_-_67205151 7.345 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr7_+_66386228 7.312 C7orf42
chromosome 7 open reading frame 42
chr5_+_172386438 7.246 NM_016093
RPL26L1
ribosomal protein L26-like 1
chr19_+_3136026 7.228 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chrX_-_129272014 7.087 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr19_-_47197162 7.021 PRKD2
protein kinase D2
chr7_+_66386237 7.018 C7orf42
chromosome 7 open reading frame 42
chr17_+_76210329 7.016 BIRC5
baculoviral IAP repeat containing 5
chr17_-_61920328 6.992 NM_001098426
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr6_-_32920812 6.986 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr20_-_44006876 6.974 NM_014477
TP53TG5
TP53 target 5
chr11_+_65101345 6.973 DPF2
D4, zinc and double PHD fingers family 2
chr11_+_17332454 6.971


chr6_-_31704272 6.955 CLIC1
chloride intracellular channel 1
chr19_+_17622445 6.936 PGLS
6-phosphogluconolactonase
chr19_+_48828627 6.934 NM_001425
EMP3
epithelial membrane protein 3
chr17_+_18768781 6.930 NM_001243940
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr6_-_31774725 6.916 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_31704281 6.914 CLIC1
chloride intracellular channel 1
chr19_-_13213513 6.865 LYL1
lymphoblastic leukemia derived sequence 1
chr11_+_118955569 6.854 NM_000190
HMBS
hydroxymethylbilane synthase
chr19_+_6361558 6.833 CLPP
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)
chr18_+_657461 6.799 NM_001071
TYMS
thymidylate synthetase
chr6_-_31704287 6.727 CLIC1
chloride intracellular channel 1
chr12_-_54689536 6.719 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_-_40042415 6.682 PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr17_+_73201528 6.644 NM_024844
NUP85
nucleoporin 85kDa
chr7_+_66386129 6.600 NM_017994
C7orf42
chromosome 7 open reading frame 42
chr6_-_31763551 6.588 NM_006295
VARS
valyl-tRNA synthetase
chr7_+_99070428 6.587 ZNF789
zinc finger protein 789
chr11_-_615998 6.575 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr18_+_3453771 6.557 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr11_+_65101224 6.554 NM_006268
DPF2
D4, zinc and double PHD fingers family 2
chr1_-_40042461 6.545 PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr13_+_103459495 6.507 NM_001204425
BIVM-ERCC5
BIVM
BIVM-ERCC5 readthrough
basic, immunoglobulin-like variable motif containing
chr19_-_8642309 6.507 NM_012335
MYO1F
myosin IF
chr1_+_28832454 6.484 NM_001048199
RCC1
regulator of chromosome condensation 1
chr3_+_9476506 6.446


chr6_-_30640781 6.437 NM_001164239
NM_003587
DHX16

DEAH (Asp-Glu-Ala-His) box polypeptide 16

chr6_-_31704304 6.414 CLIC1
chloride intracellular channel 1
chr19_+_17622420 6.404 NM_012088
PGLS
6-phosphogluconolactonase
chr19_-_54876671 6.401 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr17_-_30228715 6.354 NM_018428
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr7_+_5253816 6.347 NM_001033520
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr6_-_31704318 6.332 NM_001288
CLIC1
chloride intracellular channel 1
chr2_-_70520845 6.288 NM_003096
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr1_-_40042519 6.279 NM_001135653
NM_001135654
NM_003819
PABPC4


poly(A) binding protein, cytoplasmic 4 (inducible form)


chr1_+_247581350 6.247 NM_001127462
NM_001243133
NM_004895
NM_183395
NLRP3



NLR family, pyrin domain containing 3



chr1_-_225616556 6.241 NM_194442
LBR
lamin B receptor
chr3_-_126327397 6.230 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr3_-_50375650 6.228 NM_170712
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr6_-_31510251 6.225 NM_004640
NM_080598
DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

chr6_+_139456240 6.205 NM_016217
HECA
headcase homolog (Drosophila)
chr5_+_118691549 6.204 NM_014350
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_29077439 6.183


chr9_+_132565394 6.128 NM_014506
TOR1B
torsin family 1, member B (torsin B)
chr2_+_87140905 6.115 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr17_-_3599359 6.115 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_44614136 6.079 NM_019082
DDX56
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr22_-_42611310 6.057 NM_005650
NM_181492
TCF20

transcription factor 20 (AR1)

chr1_-_40349105 6.053 TRIT1
tRNA isopentenyltransferase 1
chr19_+_7504573 6.053 NM_001130955
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr17_+_48821106 5.999 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr6_-_30640618 5.984 DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr19_-_22966972 5.956 NM_001080409
ZNF99
zinc finger protein 99
chr1_-_1711453 5.939 NM_001198994
NADK
NAD kinase
chr12_-_13248581 5.923 NM_001206843
NM_001206845
NM_031289
NM_153823
GSG1



germ cell associated 1



chr5_+_118691692 5.918 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr11_+_60197061 5.900 NM_023945
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr19_-_8642297 5.886 MYO1F
myosin IF
chr1_+_236681513 5.868 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr1_+_161185061 5.859 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr20_+_361272 5.858 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr19_-_8642337 5.819 MYO1F
myosin IF
chr12_-_120638912 5.810 NM_001002
NM_053275
RPLP0

ribosomal protein, large, P0

chr12_-_123706393 5.807 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr16_+_30087342 5.786 NM_002720
PPP4C
protein phosphatase 4, catalytic subunit
chr16_+_28943259 5.780 NM_001178098
NM_001770
CD19

CD19 molecule

chr2_-_27357519 5.757 NM_013388
PREB
prolactin regulatory element binding
chr1_+_26872306 5.753 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr14_-_106452693 5.721 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_49028183 5.712 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr11_-_64647136 5.663 EHD1
EH-domain containing 1
chr3_-_128369525 5.640 RPN1
ribophorin I
chr19_+_36024313 5.599 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr7_+_99955625 5.593 NM_178238
PILRB
paired immunoglobin-like type 2 receptor beta
chr12_+_57881853 5.569 MARS
methionyl-tRNA synthetase
chr17_-_56358161 5.566 MPO
myeloperoxidase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.65 7.47e-12 GO:0090304 nucleic acid metabolic process
1.38 8.19e-12 GO:0043170 macromolecule metabolic process
1.69 6.84e-11 GO:0010467 gene expression
1.38 4.53e-10 GO:0044260 cellular macromolecule metabolic process
1.52 4.65e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 6.52e-10 GO:0009987 cellular process
1.29 7.01e-10 GO:0044238 primary metabolic process
1.69 9.31e-10 GO:0016070 RNA metabolic process
1.25 3.49e-09 GO:0008152 metabolic process
1.45 1.29e-08 GO:0034641 cellular nitrogen compound metabolic process
1.42 5.37e-08 GO:0006807 nitrogen compound metabolic process
2.09 1.42e-07 GO:0006396 RNA processing
2.44 1.68e-07 GO:0006397 mRNA processing
2.20 1.82e-07 GO:0016071 mRNA metabolic process
1.62 2.00e-07 GO:0009059 macromolecule biosynthetic process
1.62 2.59e-07 GO:0034645 cellular macromolecule biosynthetic process
1.25 4.39e-07 GO:0044237 cellular metabolic process
2.59 4.49e-07 GO:0006412 translation
2.33 7.32e-07 GO:0016032 viral reproduction
2.52 2.81e-06 GO:0008380 RNA splicing
2.89 3.46e-06 GO:0000375 RNA splicing, via transesterification reactions
3.79 4.89e-06 GO:0006414 translational elongation
2.89 5.56e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.89 5.56e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
3.79 8.59e-05 GO:0019080 viral genome expression
3.79 8.59e-05 GO:0019083 viral transcription
1.76 1.46e-04 GO:0043933 macromolecular complex subunit organization
3.66 1.72e-04 GO:0006415 translational termination
1.40 2.07e-04 GO:0044249 cellular biosynthetic process
3.20 2.14e-04 GO:0031018 endocrine pancreas development
1.38 4.46e-04 GO:0009058 biosynthetic process
3.21 6.54e-04 GO:0032984 macromolecular complex disassembly
3.21 6.54e-04 GO:0034623 cellular macromolecular complex disassembly
3.31 1.13e-03 GO:0043241 protein complex disassembly
3.31 1.13e-03 GO:0043624 cellular protein complex disassembly
2.54 2.16e-03 GO:0022411 cellular component disassembly
2.54 2.16e-03 GO:0071845 cellular component disassembly at cellular level
2.80 2.23e-03 GO:0031016 pancreas development
1.81 3.14e-03 GO:0071822 protein complex subunit organization
1.35 7.27e-03 GO:0006950 response to stress
1.58 9.09e-03 GO:0032774 RNA biosynthetic process
1.15 9.87e-03 GO:0065007 biological regulation
1.85 1.02e-02 GO:0034621 cellular macromolecular complex subunit organization
2.71 1.03e-02 GO:0019058 viral infectious cycle
1.49 1.94e-02 GO:0002376 immune system process
2.51 1.97e-02 GO:0022415 viral reproductive process
1.29 2.17e-02 GO:0019538 protein metabolic process
1.64 2.51e-02 GO:0006955 immune response
3.36 3.28e-02 GO:0006289 nucleotide-excision repair
4.18 3.69e-02 GO:0006283 transcription-coupled nucleotide-excision repair
1.23 3.88e-02 GO:0019222 regulation of metabolic process
2.29 3.93e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.25 4.24e-02 GO:0071843 cellular component biogenesis at cellular level
1.26 4.42e-02 GO:0060255 regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.85e-11 GO:0044424 intracellular part
1.14 4.62e-11 GO:0005622 intracellular
1.60 5.34e-11 GO:0044428 nuclear part
1.30 1.69e-09 GO:0005634 nucleus
2.25 5.07e-09 GO:0030529 ribonucleoprotein complex
1.58 3.47e-08 GO:0031981 nuclear lumen
1.50 5.94e-08 GO:0043233 organelle lumen
1.49 9.59e-08 GO:0031974 membrane-enclosed lumen
1.49 1.31e-07 GO:0070013 intracellular organelle lumen
1.37 1.44e-07 GO:0032991 macromolecular complex
1.18 1.88e-07 GO:0043227 membrane-bounded organelle
1.17 3.17e-07 GO:0043231 intracellular membrane-bounded organelle
1.15 7.28e-07 GO:0043229 intracellular organelle
1.15 7.54e-07 GO:0043226 organelle
1.63 1.39e-06 GO:0005654 nucleoplasm
1.17 2.76e-06 GO:0005737 cytoplasm
4.06 7.96e-06 GO:0022626 cytosolic ribosome
1.45 1.41e-05 GO:0005829 cytosol
1.23 1.80e-05 GO:0044422 organelle part
1.23 2.11e-05 GO:0044446 intracellular organelle part
2.99 5.67e-05 GO:0005681 spliceosomal complex
6.21 5.40e-04 GO:0005689 U12-type spliceosomal complex
1.18 1.78e-03 GO:0044444 cytoplasmic part
4.63 1.89e-03 GO:0022625 cytosolic large ribosomal subunit
2.36 3.84e-03 GO:0005840 ribosome
7.69 3.85e-03 GO:0005665 DNA-directed RNA polymerase II, core complex
3.09 1.70e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.93 2.06e-02 GO:0046930 pore complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.15 8.46e-13 GO:0003723 RNA binding
1.22 2.61e-08 GO:0005515 protein binding
1.11 1.24e-06 GO:0005488 binding
1.35 3.62e-06 GO:0003676 nucleic acid binding
2.92 5.31e-05 GO:0003735 structural constituent of ribosome
2.71 1.60e-03 GO:0004386 helicase activity
2.89 5.28e-03 GO:0008026 ATP-dependent helicase activity
2.89 5.28e-03 GO:0070035 purine NTP-dependent helicase activity
5.14 1.72e-02 GO:0019843 rRNA binding