Motif ID: RUNX1..3.p2

Z-value: 2.773


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX3chr1_-_252914740.551.7e-18Click!
RUNX1chr21_-_362609720.465.1e-13Click!
RUNX2chr6_+_453902840.283.3e-05Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_29641068 78.814 EVI2B
ecotropic viral integration site 2B
chr17_-_29641094 77.284 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_29641087 72.716 EVI2B
ecotropic viral integration site 2B
chr11_+_1889902 66.081 NM_001013253
LSP1
lymphocyte-specific protein 1
chr16_+_23847321 56.737 PRKCB
protein kinase C, beta
chr1_-_25291474 56.307 NM_001031680
RUNX3
runt-related transcription factor 3
chr6_-_32163299 54.095 NM_022107
GPSM3
G-protein signaling modulator 3
chr1_+_198608136 52.962 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_198608216 51.668 PTPRC
protein tyrosine phosphatase, receptor type, C
chr16_+_23847271 51.537 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr1_+_198608244 49.515 PTPRC
protein tyrosine phosphatase, receptor type, C
chr16_+_30194925 48.242 CORO1A
coronin, actin binding protein, 1A
chrX_-_106960028 48.165 TSC22D3
TSC22 domain family, member 3
chr10_+_70847857 47.688 SRGN
serglycin
chr2_-_158300517 46.936 NM_004288
CYTIP
cytohesin 1 interacting protein
chr4_-_84035908 46.789 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr4_-_84035888 46.567 PLAC8
placenta-specific 8
chr11_-_58345593 44.450 NM_001143995
LPXN
leupaxin
chr10_+_70847817 42.851 NM_002727
SRGN
serglycin
chr1_+_209929378 41.935 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr8_-_134072404 40.408 NM_006748
SLA
Src-like-adaptor
chrX_+_48542159 39.503 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr12_-_10542616 39.389 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr11_-_58343308 38.127 NM_004811
LPXN
leupaxin
chr16_-_68033355 37.108 NM_022355
DPEP2
dipeptidase 2
chrX_-_106960268 36.768 NM_004089
TSC22D3
TSC22 domain family, member 3
chr22_+_23222897 36.590 CYAT1
immunoglobulin lambda light chain-like
chr22_-_37640287 34.723 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_23847359 33.684 PRKCB
protein kinase C, beta
chr13_-_46756295 33.013 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_67205151 32.707 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr17_-_34524054 32.559 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr1_+_32716839 31.444 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr11_+_65647283 31.276 NM_001335
CTSW
cathepsin W
chr22_+_22786283 30.942


chr2_-_89165652 30.354


chr1_-_168513201 29.464 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chrX_-_135863104 27.733 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_+_35856990 27.640 NM_002185
IL7R
interleukin 7 receptor
chrX_-_135863033 27.199 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_-_29648631 26.936 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr2_+_85921413 26.896 NM_006433
NM_012483
GNLY

granulysin

chr22_+_22712091 26.854 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr16_+_226678 26.794 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr22_-_37640187 25.456 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_29674564 25.334 SPN
sialophorin
chrX_-_135863502 25.276 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_161185084 24.493 NM_004106
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr2_-_175462428 24.477 WIPF1
WAS/WASL interacting protein family, member 1
chr11_+_60739114 24.097 NM_006725
CD6
CD6 molecule
chr4_-_71532206 23.872 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_+_100531764 23.628 EVL
Enah/Vasp-like
chrX_-_78623006 23.316 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr22_+_23054862 23.215 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr13_+_50070527 23.139 NM_001040444
PHF11
PHD finger protein 11
chr8_-_21771111 23.089 NM_003974
DOK2
docking protein 2, 56kDa
chr1_+_161185061 22.926 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr7_-_100183753 22.793 NM_002319
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_-_39203061 22.456 FYB
FYN binding protein
chr3_-_187454247 22.247 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr4_-_71532341 22.211 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_156696351 22.194 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr14_+_93118576 21.991 RIN3
Ras and Rab interactor 3
chr5_-_149466126 21.815 CSF1R
colony stimulating factor 1 receptor
chr5_-_149466094 21.396 CSF1R
colony stimulating factor 1 receptor
chr2_+_103035148 21.382 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr5_-_149466173 21.265 CSF1R
colony stimulating factor 1 receptor
chr14_+_93118793 21.185 RIN3
Ras and Rab interactor 3
chr1_-_169680677 21.069 NM_000655
SELL
selectin L
chr14_+_100531745 21.044 NM_016337
EVL
Enah/Vasp-like
chr8_-_102803438 20.656 NM_032041
NCALD
neurocalcin delta
chr17_-_34417386 20.646 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr12_+_25205180 20.487 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr8_-_102803178 20.207 NCALD
neurocalcin delta
chr6_-_32920812 20.159 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr5_-_39219578 19.740 NM_001465
NM_199335
FYB

FYN binding protein

chr16_+_31366468 19.710 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr19_-_36233311 19.667 NM_024660
IGFLR1
IGF-like family receptor 1
chr15_+_74422589 19.480 NM_001130138
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr22_-_37975937 19.438 NM_006498
LGALS2
lectin, galactoside-binding, soluble, 2
chrX_-_47489703 19.387 NM_002621
CFP
complement factor properdin
chr13_+_31309644 19.199 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr2_+_182321618 18.463 NM_000885
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr8_-_102803196 18.047 NCALD
neurocalcin delta
chr19_-_18391440 17.860


chr16_+_28505920 17.658 NM_018690
APOBR
apolipoprotein B receptor
chr13_-_28674646 17.652 NM_004119
FLT3
fms-related tyrosine kinase 3
chr16_+_31271327 17.634 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr14_-_107013474 17.509 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr13_-_46756291 17.391 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_25205488 17.378 LRMP
lymphoid-restricted membrane protein
chr11_-_5248180 17.183 NM_000518
HBB
hemoglobin, beta
chr11_-_64512925 17.126 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_-_39270708 17.094 NM_001243093
FYB
FYN binding protein
chr5_+_54398473 16.843 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr16_+_31271311 16.721 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chrX_+_48542193 16.699 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr5_-_149492934 16.290 NM_005211
CSF1R
colony stimulating factor 1 receptor
chr17_+_72462521 16.167 NM_007261
CD300A
CD300a molecule
chr10_+_11047274 16.157 CELF2
CUGBP, Elav-like family member 2
chr12_-_51717941 15.744 BIN2
bridging integrator 2
chr12_-_54121203 15.399 NM_001143682
NM_020898
CALCOCO1

calcium binding and coiled-coil domain 1

chr13_-_41593491 15.369 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr22_+_37257004 15.343 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr12_-_51717905 15.286 NM_016293
BIN2
bridging integrator 2
chr1_-_150738255 15.119 CTSS
cathepsin S
chr12_-_112819755 15.046 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr2_-_89442551 14.732 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr10_+_11047253 14.712 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr1_+_174843523 14.711 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr17_-_1532109 14.680 NM_152346
SLC43A2
solute carrier family 43, member 2
chr22_+_23154240 14.608


chr5_-_137071462 14.590 KLHL3
kelch-like 3 (Drosophila)
chr13_-_41593405 14.547 ELF1
E74-like factor 1 (ets domain transcription factor)
chr15_-_22473092 14.457


chr5_-_176326314 14.454 NM_002115
HK3
hexokinase 3 (white cell)
chr10_-_126432893 14.317 NM_014661
FAM53B
family with sequence similarity 53, member B
chr19_-_2151332 14.236 AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr1_+_32739711 14.053 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr14_-_106780535 13.959 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_123688352 13.877 TRAF1
TNF receptor-associated factor 1
chr21_+_42733916 13.798 NM_002463
LOC100131190
MX2
uncharacterized LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr2_+_68592432 13.565 PLEK
pleckstrin
chr19_+_55085273 13.552 LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr2_+_68592317 13.461 NM_002664
PLEK
pleckstrin
chr19_+_51728369 13.355 CD33
CD33 molecule
chr1_-_92951593 13.318 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr13_+_31309690 13.239 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_-_3786221 13.017 MATK
megakaryocyte-associated tyrosine kinase
chr19_+_50015535 12.981 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_47813074 12.953 NM_001736
C5AR1
complement component 5a receptor 1
chr1_-_203155827 12.925 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_54746599 12.901 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr16_+_31271277 12.866 NM_000632
NM_001145808
ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

chr1_+_168545710 12.854 NM_002995
XCL1
chemokine (C motif) ligand 1
chr13_-_46756326 12.687 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_192544856 12.623 NM_002922
RGS1
regulator of G-protein signaling 1
chr4_+_8951476 12.601 NM_001040071
LOC650293
seven transmembrane helix receptor
chr2_+_90077732 12.572


chr11_+_2323236 12.551 NM_139022
TSPAN32
tetraspanin 32
chr11_-_128457452 12.537 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr17_-_1531543 12.477 SLC43A2
solute carrier family 43, member 2
chr1_-_203155867 12.453 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr4_-_38806410 12.382 NM_003263
TLR1
toll-like receptor 1
chr5_+_75699003 12.378 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr11_-_5275904 12.351 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr16_-_28621279 12.321 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr6_-_35696359 12.112 NM_001145775
FKBP5
FK506 binding protein 5
chr17_+_45810609 12.062 NM_013351
TBX21
T-box 21
chr8_+_1952875 12.030 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_+_44637539 11.982 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_128175989 11.807 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr19_-_18392048 11.787 JUND
jun D proto-oncogene
chr11_+_67033929 11.735 ADRBK1
adrenergic, beta, receptor kinase 1
chr19_+_50015868 11.725 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_-_150920946 11.631 NM_013308
GPR171
G protein-coupled receptor 171
chr6_-_31550065 11.608 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr6_+_31982538 11.526 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr3_-_151047309 11.525 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr14_+_74551655 11.456 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr21_-_36421630 11.395 RUNX1
runt-related transcription factor 1
chr19_+_3136026 11.376 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr4_-_74847669 11.159 NM_002619
PF4
platelet factor 4
chr1_-_160832466 11.152 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr15_-_34875060 11.036 GOLGA8B
golgin A8 family, member B
chr12_-_51717835 11.034 BIN2
bridging integrator 2
chr2_+_182322265 11.033 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr22_-_19419177 11.012 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_17634689 10.948 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr19_-_3786382 10.812 NM_139354
NM_139355
MATK

megakaryocyte-associated tyrosine kinase

chr22_-_31688329 10.806 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr11_-_5255712 10.742 NM_000519
HBD
hemoglobin, delta
chr12_-_109025825 10.729 NM_001206609
SELPLG
selectin P ligand
chr22_+_40297183 10.686 GRAP2
GRB2-related adaptor protein 2
chr1_-_203155910 10.650 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr15_+_75494235 10.633 C15orf39
chromosome 15 open reading frame 39
chr11_+_46366816 10.616 NM_201533
DGKZ
diacylglycerol kinase, zeta
chr1_-_173174611 10.614 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr15_-_40600025 10.313 PLCB2
phospholipase C, beta 2
chr17_-_56606710 10.269 NM_004574
SEPT4
septin 4
chr6_+_31949800 10.240 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr6_+_72926462 10.230 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_203155745 10.222 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_2151551 10.220 NM_001077523
NM_003938
AP3D1

adaptor-related protein complex 3, delta 1 subunit

chr18_+_77253324 10.107 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_+_51645556 10.056 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr2_-_74756823 10.041 AUP1
ancient ubiquitous protein 1
chr22_+_40297085 10.019 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr10_+_129845806 10.011 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_-_207095198 10.006 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr14_+_21423627 10.004 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr6_-_32784727 9.998 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr9_+_123963728 9.915 GSN
gelsolin
chr22_-_19418998 9.890 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_-_19419215 9.756 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr15_+_75494233 9.713 C15orf39
chromosome 15 open reading frame 39
chr19_+_51728319 9.601 NM_001082618
NM_001177608
NM_001772
CD33


CD33 molecule


chr17_-_79008372 9.578 FLJ90757
uncharacterized LOC440465
chr11_+_67033889 9.544 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr22_+_35695267 9.484 NM_001135729
TOM1
target of myb1 (chicken)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.25 1.34e-23 GO:0002376 immune system process
2.41 9.77e-17 GO:0006955 immune response
1.34 7.40e-15 GO:0050896 response to stimulus
1.48 2.18e-13 GO:0023052 signaling
1.26 5.03e-13 GO:0065007 biological regulation
1.48 1.21e-11 GO:0007165 signal transduction
1.26 1.38e-11 GO:0050789 regulation of biological process
1.26 5.41e-10 GO:0050794 regulation of cellular process
2.39 5.65e-10 GO:0001775 cell activation
1.37 5.83e-09 GO:0051716 cellular response to stimulus
1.14 1.55e-08 GO:0009987 cellular process
1.92 1.75e-08 GO:0009611 response to wounding
1.60 1.99e-08 GO:0048583 regulation of response to stimulus
2.04 3.93e-08 GO:0002682 regulation of immune system process
1.93 1.11e-07 GO:0006952 defense response
1.29 1.29e-07 GO:0032501 multicellular organismal process
1.47 5.19e-07 GO:0006950 response to stress
1.56 6.60e-07 GO:0007166 cell surface receptor linked signaling pathway
1.49 1.32e-06 GO:0065008 regulation of biological quality
2.93 1.40e-06 GO:0046649 lymphocyte activation
1.64 5.67e-06 GO:0051239 regulation of multicellular organismal process
1.80 8.16e-06 GO:0040011 locomotion
2.06 2.69e-05 GO:0007596 blood coagulation
2.06 2.69e-05 GO:0050817 coagulation
2.04 3.54e-05 GO:0007599 hemostasis
2.10 4.50e-05 GO:0002684 positive regulation of immune system process
1.39 4.83e-05 GO:0048518 positive regulation of biological process
1.95 6.39e-05 GO:0050878 regulation of body fluid levels
2.07 6.56e-05 GO:0050776 regulation of immune response
1.80 7.35e-05 GO:0007267 cell-cell signaling
1.77 8.64e-05 GO:0048584 positive regulation of response to stimulus
2.35 8.70e-05 GO:0050778 positive regulation of immune response
2.55 9.88e-05 GO:0002253 activation of immune response
2.48 1.04e-04 GO:0045321 leukocyte activation
1.92 2.17e-04 GO:0006928 cellular component movement
1.41 2.65e-04 GO:0042221 response to chemical stimulus
3.09 4.88e-04 GO:0042110 T cell activation
1.63 7.06e-04 GO:0007154 cell communication
2.75 9.08e-04 GO:0050900 leukocyte migration
2.00 1.37e-03 GO:0016477 cell migration
1.96 1.41e-03 GO:0051094 positive regulation of developmental process
1.87 1.88e-03 GO:0080134 regulation of response to stress
1.33 1.96e-03 GO:0048731 system development
2.34 1.99e-03 GO:0030168 platelet activation
1.36 2.05e-03 GO:0048522 positive regulation of cellular process
2.23 2.20e-03 GO:0001817 regulation of cytokine production
2.54 2.45e-03 GO:0002757 immune response-activating signal transduction
1.80 2.55e-03 GO:0042060 wound healing
2.48 4.16e-03 GO:0002764 immune response-regulating signaling pathway
1.83 6.07e-03 GO:0006935 chemotaxis
1.83 6.07e-03 GO:0042330 taxis
1.88 6.29e-03 GO:0048870 cell motility
1.88 6.29e-03 GO:0051674 localization of cell
1.35 6.70e-03 GO:0048519 negative regulation of biological process
2.22 7.60e-03 GO:0051241 negative regulation of multicellular organismal process
2.03 1.22e-02 GO:0031347 regulation of defense response
1.82 1.33e-02 GO:0019226 transmission of nerve impulse
1.82 1.33e-02 GO:0035637 multicellular organismal signaling
1.87 1.40e-02 GO:0007268 synaptic transmission
3.30 1.43e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.55 1.44e-02 GO:0009605 response to external stimulus
1.28 1.52e-02 GO:0048856 anatomical structure development
3.21 2.14e-02 GO:0002250 adaptive immune response
2.12 3.17e-02 GO:0050865 regulation of cell activation
2.04 3.55e-02 GO:0006954 inflammatory response
1.90 3.69e-02 GO:0045087 innate immune response
1.25 4.44e-02 GO:0007275 multicellular organismal development
1.42 4.52e-02 GO:0065009 regulation of molecular function

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.66 2.38e-14 GO:0044459 plasma membrane part
1.89 3.42e-13 GO:0005887 integral to plasma membrane
1.87 4.01e-13 GO:0031226 intrinsic to plasma membrane
1.33 8.23e-08 GO:0005886 plasma membrane
1.32 1.57e-07 GO:0071944 cell periphery
1.75 1.71e-05 GO:0005615 extracellular space
2.56 3.02e-03 GO:0009897 external side of plasma membrane
1.50 5.11e-03 GO:0044421 extracellular region part
6.78 3.80e-02 GO:0005833 hemoglobin complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.77 5.69e-07 GO:0003823 antigen binding
1.18 2.86e-05 GO:0005515 protein binding
2.64 6.56e-05 GO:0005126 cytokine receptor binding
1.40 2.21e-04 GO:0004871 signal transducer activity
1.40 2.21e-04 GO:0060089 molecular transducer activity
6.43 1.90e-03 GO:0005164 tumor necrosis factor receptor binding
1.40 2.66e-03 GO:0004872 receptor activity
4.81 4.62e-03 GO:0032813 tumor necrosis factor receptor superfamily binding
3.72 8.19e-03 GO:0042379 chemokine receptor binding
2.24 8.97e-03 GO:0005125 cytokine activity
3.92 9.08e-03 GO:0019825 oxygen binding
1.49 1.25e-02 GO:0005102 receptor binding
1.08 1.39e-02 GO:0005488 binding
1.58 3.11e-02 GO:0043565 sequence-specific DNA binding
1.46 4.75e-02 GO:0001071 nucleic acid binding transcription factor activity
1.46 4.75e-02 GO:0003700 sequence-specific DNA binding transcription factor activity