Motif ID: SOX17.p2

Z-value: 1.737


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_55370494-0.195.2e-03Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153643456 76.789 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_153643474 74.145 NM_004515
ILF2
interleukin enhancer binding factor 2, 45kDa
chr7_-_44887620 73.359 H2AFV
H2A histone family, member V
chr1_-_153643433 72.914 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_153643428 71.116 ILF2
interleukin enhancer binding factor 2, 45kDa
chr7_-_44887567 71.035 H2AFV
H2A histone family, member V
chr1_-_153643417 69.686 ILF2
interleukin enhancer binding factor 2, 45kDa
chr5_+_177631533 62.366 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_177631496 60.472 NM_004499
NM_031266
HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr17_-_73150493 54.893 HN1
hematological and neurological expressed 1
chr5_+_177631534 52.701 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr16_+_56817367 51.279 NM_001242796
NUP93
nucleoporin 93kDa
chr5_+_68462948 47.491 CCNB1
cyclin B1
chr5_+_68462985 42.820 CCNB1
cyclin B1
chr13_-_31040035 41.519 NM_002128
HMGB1
high mobility group box 1
chr2_-_61765394 39.813 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_+_43824598 39.506 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr13_-_31039966 37.700 HMGB1
high mobility group box 1
chr5_+_68462836 33.728 NM_031966
CCNB1
cyclin B1
chr1_+_110882063 30.411 RBM15
RNA binding motif protein 15
chr1_-_26232890 30.382 NM_001145454
NM_005563
STMN1

stathmin 1

chr1_+_154947116 30.165 NM_001826
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr14_+_52456322 30.055 C14orf166
chromosome 14 open reading frame 166
chr2_+_10262694 29.819 NM_001165931
RRM2
ribonucleotide reductase M2
chr2_-_61765367 29.809 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_+_154947147 29.744 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr2_-_61765345 29.467 XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_-_8113862 29.428 NM_004217
AURKB
aurora kinase B
chr2_+_10262853 28.953 NM_001034
RRM2
ribonucleotide reductase M2
chr17_+_26646120 28.459 NM_014573
TMEM97
transmembrane protein 97
chr3_-_52567708 28.451 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr16_+_56815703 28.420 NM_001242795
NUP93
nucleoporin 93kDa
chr1_+_110882057 28.379 RBM15
RNA binding motif protein 15
chr6_-_53213586 27.756 ELOVL5
ELOVL fatty acid elongase 5
chr14_+_52456192 27.721 NM_016039
C14orf166
chromosome 14 open reading frame 166
chr1_+_154947166 27.700 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr6_+_30688144 27.428 NM_178014
TUBB
tubulin, beta class I
chr3_-_52567809 27.367 NT5DC2
5'-nucleotidase domain containing 2
chr1_+_110881944 26.549 NM_001201545
NM_022768
RBM15

RNA binding motif protein 15

chr19_+_13049413 26.343 NM_004343
CALR
calreticulin
chr2_+_27008881 25.716 NM_001809
NM_001042426
CENPA

centromere protein A

chr19_-_55919324 24.712 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr19_+_13049428 24.321 CALR
calreticulin
chr6_+_30688085 24.148 TUBB
tubulin, beta class I
chr1_-_26233367 23.225 NM_203399
STMN1
stathmin 1
chr16_-_103557 23.136 NM_016310
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr19_+_13049440 22.849 CALR
calreticulin
chr17_+_66031814 22.356 NM_002266
KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_12727204 22.248 ARL4A
ADP-ribosylation factor-like 4A
chr17_+_66031885 21.481 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr6_-_79944397 20.905 NM_001201362
NM_001201363
NM_004242
NM_138730
HMGN3



high mobility group nucleosomal binding domain 3



chr20_-_5107185 20.542 NM_002592
PCNA
proliferating cell nuclear antigen
chr1_-_8931634 20.534 NM_001201483
ENO1
enolase 1, (alpha)
chr11_-_16996559 20.513 RPL36A
ribosomal protein L36a
chr1_-_197115566 20.383 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr3_+_51422716 20.282 MANF
mesencephalic astrocyte-derived neurotrophic factor
chr2_+_74425689 19.777 NM_006636
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr20_+_44441247 19.585 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr13_+_53029494 19.523 NM_001098525
NM_018204
CKAP2

cytoskeleton associated protein 2

chr14_-_64009971 19.503 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_103859 19.368 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr12_-_102512277 19.297 NM_024057
NUP37
nucleoporin 37kDa
chr2_+_232573226 19.119 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr12_-_6960406 19.007 NM_031299
CDCA3
cell division cycle associated 3
chr3_+_51422691 18.742 NM_006010
MANF
mesencephalic astrocyte-derived neurotrophic factor
chr15_+_59397276 18.741 NM_004701
CCNB2
cyclin B2
chr20_-_49547451 18.721 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr6_-_79944324 18.607 HMGN3
high mobility group nucleosomal binding domain 3
chr1_-_26232643 18.511 NM_203401
STMN1
stathmin 1
chr20_+_44441334 18.311 UBE2C
ubiquitin-conjugating enzyme E2C
chr2_+_27008912 17.945 CENPA
centromere protein A
chr9_-_128003634 17.941 NM_005347
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr4_-_122744782 17.762 CCNA2
cyclin A2
chr4_-_122744978 17.455 NM_001237
CCNA2
cyclin A2
chr14_-_64010087 17.432 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_103892 17.409 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_+_75061234 17.380 HK2
hexokinase 2
chr6_+_27114860 17.319 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr14_-_64010063 16.909 NM_006246
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr11_-_46867840 16.744 NM_001008938
NM_014756
CKAP5

cytoskeleton associated protein 5

chr16_-_58663734 16.643 CNOT1
CCR4-NOT transcription complex, subunit 1
chr6_-_108279307 16.463 SEC63
SEC63 homolog (S. cerevisiae)
chr4_-_100871482 16.451 NM_002106
H2AFZ
H2A histone family, member Z
chr1_+_24286300 16.441 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr17_+_1733263 16.336 NM_002945
RPA1
replication protein A1, 70kDa
chr12_-_31479120 16.223 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr6_-_86351156 15.917 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr6_+_80714321 15.893 NM_001166691
NM_003318
TTK

TTK protein kinase

chr4_-_100871431 15.736 H2AFZ
H2A histone family, member Z
chr17_-_38574042 15.541 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr6_-_150067631 15.539 NM_198887
NUP43
nucleoporin 43kDa
chr1_-_109969058 15.335 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr12_-_31479038 15.330 FAM60A
family with sequence similarity 60, member A
chr11_-_102323353 15.329 NM_052932
TMEM123
transmembrane protein 123
chr7_+_73097897 15.282 NM_001202560
NM_017528
WBSCR22

Williams Beuren syndrome chromosome region 22

chr6_+_24775640 15.251 NM_001251991
GMNN
geminin, DNA replication inhibitor
chr1_+_43148096 15.178 YBX1
Y box binding protein 1
chr9_-_128003615 15.123 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr6_+_80714389 15.055 TTK
TTK protein kinase
chr14_+_103800534 14.944 EIF5
eukaryotic translation initiation factor 5
chr5_+_159848835 14.856 NM_004219
PTTG1
pituitary tumor-transforming 1
chr12_-_31479084 14.659 FAM60A
family with sequence similarity 60, member A
chr4_-_7069801 14.552 GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr15_-_64673569 14.419 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr20_+_44441671 14.239 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr17_+_1733313 14.182 RPA1
replication protein A1, 70kDa
chr14_+_23938883 14.149 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr10_-_13390189 14.149 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr1_-_109969044 14.023 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr12_+_120933911 14.016 DYNLL1
dynein, light chain, LC8-type 1
chr5_+_145826866 13.966 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chrX_+_153991016 13.916 NM_001142463
NM_001363
DKC1

dyskeratosis congenita 1, dyskerin

chr13_+_98628712 13.807 IPO5
importin 5
chr5_+_138941323 13.651 UBE2D2
ubiquitin-conjugating enzyme E2D 2
chr7_+_16685757 13.629 NM_001159767
NM_014038
BZW2

basic leucine zipper and W2 domains 2

chr11_+_747428 13.563 NM_006755
TALDO1
transaldolase 1
chr8_+_98656494 13.537 MTDH
metadherin
chr7_-_44887697 13.495 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr14_+_97263681 13.469 NM_003384
VRK1
vaccinia related kinase 1
chr6_+_111135823 13.379 AMD1
adenosylmethionine decarboxylase 1
chr17_+_7476023 13.362 NM_001204510
NM_001416
EIF4A1

eukaryotic translation initiation factor 4A1

chr12_+_69979447 13.334 NM_001198842
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr19_-_8070468 13.319 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr8_+_98656428 13.246 MTDH
metadherin
chr2_-_10952803 13.228 PDIA6
protein disulfide isomerase family A, member 6
chr2_-_174830429 13.218 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr5_+_102465256 13.198 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr15_-_59225766 13.056 SLTM
SAFB-like, transcription modulator
chr5_-_137878808 13.033 ETF1
eukaryotic translation termination factor 1
chr2_-_9770999 12.949 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr22_+_38142255 12.889 TRIOBP
TRIO and F-actin binding protein
chr12_+_98909331 12.848 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr19_+_45394459 12.824 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chr1_+_24286311 12.743 PNRC2
proline-rich nuclear receptor coactivator 2
chr1_+_180897572 12.710


chr12_+_120933832 12.708 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr15_-_69113255 12.703 NM_006305
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_131451519 12.665 SET
SET nuclear oncogene
chr11_+_747424 12.656 TALDO1
transaldolase 1
chr8_-_101965601 12.655 NM_003406
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr6_+_20402040 12.617 NM_001949
E2F3
E2F transcription factor 3
chr7_+_141438122 12.594 NM_003143
SSBP1
single-stranded DNA binding protein 1
chr14_+_102276125 12.503 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr11_+_34073188 12.430 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr2_-_10952855 12.408 NM_005742
PDIA6
protein disulfide isomerase family A, member 6
chr1_+_43148098 12.253 YBX1
Y box binding protein 1
chr5_-_137878915 12.238 NM_004730
ETF1
eukaryotic translation termination factor 1
chr9_+_131445933 12.197 NM_001122821
SET
SET nuclear oncogene
chr11_+_36317724 12.168 NM_001160167
PRR5L
proline rich 5 like
chr1_-_150208462 12.068 NM_001136478
NM_030920
ANP32E

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr6_+_114178516 12.057 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr5_+_159848876 11.986 PTTG1
pituitary tumor-transforming 1
chr14_+_58711599 11.922 PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr2_-_9771101 11.892 NM_006826
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr9_+_131451847 11.877 SET
SET nuclear oncogene
chr15_+_66694216 11.821 MAP2K1
mitogen-activated protein kinase kinase 1
chr8_-_101965194 11.797 NM_001135699
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_123237302 11.792 NM_003677
DENR
density-regulated protein
chr14_+_103800678 11.754 EIF5
eukaryotic translation initiation factor 5
chr7_+_134464417 11.750 CALD1
caldesmon 1
chr15_+_41625052 11.742 NUSAP1
nucleolar and spindle associated protein 1
chr12_+_104324157 11.634 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr16_-_75529278 11.607


chr1_+_167298280 11.582 NM_001198783
POU2F1
POU class 2 homeobox 1
chr14_-_35344450 11.480 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr14_+_20937537 11.460 NM_000270
PNP
purine nucleoside phosphorylase
chr9_-_128003348 11.401 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr19_+_17970670 11.362 NM_000980
RPL18A
ribosomal protein L18a
chr1_+_43148048 11.349 NM_004559
YBX1
Y box binding protein 1
chr15_+_41625152 11.342 NUSAP1
nucleolar and spindle associated protein 1
chr9_+_131451470 11.338 NM_003011
SET
SET nuclear oncogene
chr12_+_56211862 11.190 ORMDL2
ORM1-like 2 (S. cerevisiae)
chr1_+_62902325 11.134 NM_003368
USP1
ubiquitin specific peptidase 1
chrX_-_151999259 11.131 NM_004344
CETN2
centrin, EF-hand protein, 2
chr10_+_22610138 11.084 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_150208441 11.081 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_73150769 11.035 NM_001002032
NM_001002033
NM_016185
HN1


hematological and neurological expressed 1


chr4_-_100871418 11.025 H2AFZ
H2A histone family, member Z
chr2_-_234763182 11.012 NM_018410
HJURP
Holliday junction recognition protein
chr1_+_43148105 10.948 YBX1
Y box binding protein 1
chr1_-_151032082 10.931 NM_001038707
NM_020239
CDC42SE1

CDC42 small effector 1

chr1_-_20988023 10.896 NM_005216
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr2_-_234763145 10.893 HJURP
Holliday junction recognition protein
chr11_+_747449 10.838 TALDO1
transaldolase 1
chr6_+_30689414 10.780 TUBB
tubulin, beta class I
chr10_+_94050858 10.733 NM_017824
MARCH5
membrane-associated ring finger (C3HC4) 5
chr12_+_104324192 10.669 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_-_120638894 10.655 RPLP0
ribosomal protein, large, P0
chr1_-_27816676 10.616 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr1_-_109968951 10.607 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr1_+_155278538 10.594 NM_001135822
NM_001242824
NM_001242825
NM_002004
FDPS



farnesyl diphosphate synthase



chr5_+_154092461 10.567 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr15_-_69113213 10.556 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr3_-_57583080 10.539 ARF4
ADP-ribosylation factor 4
chr6_-_53213699 10.489 ELOVL5
ELOVL fatty acid elongase 5
chr1_-_33815340 10.464 PHC2
polyhomeotic homolog 2 (Drosophila)
chr1_+_43148142 10.386 YBX1
Y box binding protein 1
chr1_+_155278727 10.350 FDPS
farnesyl diphosphate synthase
chr8_-_109260940 10.309 NM_001568
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr14_+_102276279 10.281 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 1.99e-32 GO:0009987 cellular process
1.61 4.00e-29 GO:0044260 cellular macromolecule metabolic process
1.45 4.45e-28 GO:0044237 cellular metabolic process
1.89 6.79e-25 GO:0090304 nucleic acid metabolic process
1.77 1.31e-24 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 3.56e-23 GO:0034641 cellular nitrogen compound metabolic process
1.66 3.90e-23 GO:0006807 nitrogen compound metabolic process
1.40 3.55e-22 GO:0044238 primary metabolic process
1.48 1.54e-21 GO:0043170 macromolecule metabolic process
1.35 2.96e-21 GO:0008152 metabolic process
1.93 3.88e-20 GO:0016070 RNA metabolic process
1.60 9.83e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.76 1.51e-14 GO:0010467 gene expression
1.51 2.63e-14 GO:0071840 cellular component organization or biogenesis
1.82 2.69e-14 GO:0006996 organelle organization
1.60 6.40e-14 GO:0071842 cellular component organization at cellular level
1.51 8.91e-14 GO:0016043 cellular component organization
2.41 7.80e-13 GO:0000278 mitotic cell cycle
1.73 8.34e-12 GO:0009059 macromolecule biosynthetic process
2.41 9.68e-12 GO:0016071 mRNA metabolic process
1.73 9.69e-12 GO:0034645 cellular macromolecule biosynthetic process
1.57 5.93e-11 GO:0044249 cellular biosynthetic process
1.92 2.79e-10 GO:0007049 cell cycle
1.54 3.22e-10 GO:0009058 biosynthetic process
2.15 3.34e-10 GO:0022403 cell cycle phase
2.79 6.81e-10 GO:0051329 interphase of mitotic cell cycle
2.02 1.01e-09 GO:0022402 cell cycle process
2.74 1.53e-09 GO:0051325 interphase
1.24 3.25e-09 GO:0050789 regulation of biological process
1.25 4.73e-09 GO:0050794 regulation of cellular process
1.54 2.91e-08 GO:0048523 negative regulation of cellular process
2.07 5.05e-08 GO:0006396 RNA processing
1.40 5.53e-08 GO:0060255 regulation of macromolecule metabolic process
1.21 6.61e-08 GO:0065007 biological regulation
2.08 6.70e-08 GO:0051276 chromosome organization
1.49 7.36e-08 GO:0048522 positive regulation of cellular process
1.74 8.26e-08 GO:0044085 cellular component biogenesis
1.47 2.25e-07 GO:0044267 cellular protein metabolic process
1.48 2.61e-07 GO:0048519 negative regulation of biological process
2.53 3.67e-07 GO:0008380 RNA splicing
2.03 3.74e-07 GO:0051726 regulation of cell cycle
2.19 5.62e-07 GO:0006325 chromatin organization
2.15 7.39e-07 GO:0034621 cellular macromolecular complex subunit organization
1.81 8.16e-07 GO:0010605 negative regulation of macromolecule metabolic process
2.39 8.84e-07 GO:0010564 regulation of cell cycle process
1.43 1.15e-06 GO:0048518 positive regulation of biological process
1.44 1.22e-06 GO:0010468 regulation of gene expression
1.70 1.75e-06 GO:0010604 positive regulation of macromolecule metabolic process
2.33 1.78e-06 GO:0034622 cellular macromolecular complex assembly
1.76 2.55e-06 GO:0032774 RNA biosynthetic process
1.75 2.75e-06 GO:0009892 negative regulation of metabolic process
1.35 2.93e-06 GO:0031323 regulation of cellular metabolic process
1.67 3.23e-06 GO:0031325 positive regulation of cellular metabolic process
1.72 3.45e-06 GO:0022607 cellular component assembly
1.81 4.56e-06 GO:0043933 macromolecular complex subunit organization
2.78 4.86e-06 GO:0000375 RNA splicing, via transesterification reactions
1.32 6.73e-06 GO:0019222 regulation of metabolic process
1.86 6.96e-06 GO:0071844 cellular component assembly at cellular level
1.97 7.28e-06 GO:0010629 negative regulation of gene expression
2.23 7.56e-06 GO:0006397 mRNA processing
1.88 1.08e-05 GO:0065003 macromolecular complex assembly
1.82 1.20e-05 GO:0046907 intracellular transport
1.77 1.20e-05 GO:0006351 transcription, DNA-dependent
1.63 1.21e-05 GO:0009893 positive regulation of metabolic process
1.44 1.59e-05 GO:0051252 regulation of RNA metabolic process
1.33 1.69e-05 GO:0080090 regulation of primary metabolic process
1.61 1.91e-05 GO:0051641 cellular localization
1.66 2.40e-05 GO:0051649 establishment of localization in cell
2.71 2.43e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.71 2.43e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.72 5.35e-05 GO:0031324 negative regulation of cellular metabolic process
2.06 8.49e-05 GO:0000279 M phase
1.75 9.36e-05 GO:0051128 regulation of cellular component organization
1.40 1.15e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.10 1.51e-04 GO:0050657 nucleic acid transport
3.10 1.51e-04 GO:0050658 RNA transport
3.10 1.51e-04 GO:0051236 establishment of RNA localization
1.38 1.88e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.92 2.22e-04 GO:0044265 cellular macromolecule catabolic process
2.46 2.50e-04 GO:0071156 regulation of cell cycle arrest
2.50 2.51e-04 GO:0000075 cell cycle checkpoint
1.91 2.62e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.90 2.76e-04 GO:0051253 negative regulation of RNA metabolic process
3.00 3.22e-04 GO:0006403 RNA localization
1.83 3.35e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.23 3.39e-04 GO:0000087 M phase of mitotic cell cycle
1.35 4.66e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.82 4.93e-04 GO:0000082 G1/S transition of mitotic cell cycle
2.61 5.40e-04 GO:0006913 nucleocytoplasmic transport
1.79 5.48e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.48 6.48e-04 GO:0006605 protein targeting
2.58 7.23e-04 GO:0051169 nuclear transport
2.20 9.28e-04 GO:0000280 nuclear division
2.20 9.28e-04 GO:0007067 mitosis
2.18 9.65e-04 GO:0048285 organelle fission
2.07 9.81e-04 GO:0044419 interspecies interaction between organisms
2.06 1.08e-03 GO:0016568 chromatin modification
1.26 1.19e-03 GO:0051716 cellular response to stimulus
3.02 1.27e-03 GO:0051028 mRNA transport
1.34 1.34e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70 1.52e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 1.54e-03 GO:0006355 regulation of transcription, DNA-dependent
1.74 1.58e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.63 1.59e-03 GO:0010498 proteasomal protein catabolic process
2.63 1.59e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.22 1.75e-03 GO:0007346 regulation of mitotic cell cycle
1.73 1.94e-03 GO:0009890 negative regulation of biosynthetic process
1.65 2.40e-03 GO:0033554 cellular response to stress
3.39 2.52e-03 GO:0006839 mitochondrial transport
1.69 2.52e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.51 2.53e-03 GO:0010033 response to organic substance
1.67 3.00e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.93 3.92e-03 GO:0000086 G2/M transition of mitotic cell cycle
2.67 4.00e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.75 4.05e-03 GO:0009057 macromolecule catabolic process
2.90 4.68e-03 GO:0000084 S phase of mitotic cell cycle
1.71 5.07e-03 GO:0051254 positive regulation of RNA metabolic process
1.62 5.48e-03 GO:0031328 positive regulation of cellular biosynthetic process
2.74 5.66e-03 GO:0007093 mitotic cell cycle checkpoint
1.30 5.68e-03 GO:0019538 protein metabolic process
1.76 5.87e-03 GO:0006259 DNA metabolic process
1.32 6.12e-03 GO:0031326 regulation of cellular biosynthetic process
2.56 6.43e-03 GO:0071103 DNA conformation change
2.85 6.61e-03 GO:0051320 S phase
1.40 7.36e-03 GO:0006464 protein modification process
2.12 8.23e-03 GO:0010608 posttranscriptional regulation of gene expression
2.04 8.54e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.72 8.92e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.72 9.47e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.86 9.90e-03 GO:0090068 positive regulation of cell cycle process
1.38 1.08e-02 GO:0043412 macromolecule modification
2.41 1.10e-02 GO:0016570 histone modification
1.60 1.13e-02 GO:0009891 positive regulation of biosynthetic process
2.83 1.17e-02 GO:0065004 protein-DNA complex assembly
1.96 1.30e-02 GO:0051301 cell division
1.55 1.33e-02 GO:0042127 regulation of cell proliferation
1.67 1.39e-02 GO:0010628 positive regulation of gene expression
1.31 1.42e-02 GO:0009889 regulation of biosynthetic process
2.00 1.48e-02 GO:0019941 modification-dependent protein catabolic process
1.70 1.49e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.37 1.60e-02 GO:0016569 covalent chromatin modification
1.98 1.77e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.49 1.83e-02 GO:0044248 cellular catabolic process
1.76 2.52e-02 GO:0034613 cellular protein localization
1.53 2.67e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.95 2.99e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.74 3.08e-02 GO:0070727 cellular macromolecule localization
2.68 3.09e-02 GO:0071824 protein-DNA complex subunit organization
2.24 3.94e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.19 4.60e-02 GO:0071843 cellular component biogenesis at cellular level
2.84 4.71e-02 GO:0006334 nucleosome assembly
2.61 4.86e-02 GO:0017038 protein import
1.91 4.94e-02 GO:0044257 cellular protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 9.06e-38 GO:0044424 intracellular part
1.24 2.01e-35 GO:0005622 intracellular
1.53 3.88e-34 GO:0005634 nucleus
1.30 7.30e-33 GO:0043229 intracellular organelle
1.30 8.16e-33 GO:0043226 organelle
1.33 7.99e-31 GO:0043227 membrane-bounded organelle
1.33 1.01e-30 GO:0043231 intracellular membrane-bounded organelle
1.92 8.11e-28 GO:0044428 nuclear part
1.87 4.02e-27 GO:0031974 membrane-enclosed lumen
1.87 5.97e-27 GO:0043233 organelle lumen
1.87 6.06e-26 GO:0070013 intracellular organelle lumen
1.96 1.37e-24 GO:0031981 nuclear lumen
1.45 5.74e-24 GO:0044446 intracellular organelle part
1.44 2.48e-23 GO:0044422 organelle part
2.10 6.77e-22 GO:0005654 nucleoplasm
1.54 2.65e-18 GO:0032991 macromolecular complex
1.27 7.31e-18 GO:0005737 cytoplasm
1.46 4.06e-10 GO:0043234 protein complex
2.04 4.62e-10 GO:0044451 nucleoplasm part
1.56 7.24e-10 GO:0005829 cytosol
1.42 1.18e-07 GO:0043228 non-membrane-bounded organelle
1.42 1.18e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.24 1.85e-07 GO:0044444 cytoplasmic part
2.68 4.13e-07 GO:0016604 nuclear body
2.06 4.71e-07 GO:0030529 ribonucleoprotein complex
1.06 1.03e-06 GO:0044464 cell part
1.06 1.07e-06 GO:0005623 cell
1.97 2.19e-06 GO:0005694 chromosome
1.80 1.15e-05 GO:0031967 organelle envelope
1.79 1.36e-05 GO:0031975 envelope
1.99 2.03e-05 GO:0044427 chromosomal part
7.26 7.63e-05 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.27 3.90e-04 GO:0000785 chromatin
3.41 1.37e-03 GO:0005643 nuclear pore
4.79 3.28e-03 GO:0000932 cytoplasmic mRNA processing body
2.99 5.83e-03 GO:0046930 pore complex
3.50 6.36e-03 GO:0016605 PML body
2.00 2.38e-02 GO:0005635 nuclear envelope
2.64 2.42e-02 GO:0005788 endoplasmic reticulum lumen
2.05 2.89e-02 GO:0000228 nuclear chromosome
1.69 3.10e-02 GO:0005740 mitochondrial envelope
3.56 3.74e-02 GO:0017053 transcriptional repressor complex
2.61 4.24e-02 GO:0032993 protein-DNA complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 1.05e-45 GO:0005515 protein binding
1.21 2.13e-27 GO:0005488 binding
1.48 3.79e-13 GO:0003676 nucleic acid binding
2.08 1.75e-12 GO:0003723 RNA binding
1.67 6.63e-06 GO:0030528 transcription regulator activity
1.40 1.67e-05 GO:0003677 DNA binding
1.40 3.10e-05 GO:0000166 nucleotide binding
2.13 2.52e-04 GO:0016564 transcription repressor activity
2.01 2.91e-04 GO:0003712 transcription cofactor activity
2.00 3.18e-04 GO:0000988 protein binding transcription factor activity
2.00 3.18e-04 GO:0000989 transcription factor binding transcription factor activity
2.06 2.10e-03 GO:0008134 transcription factor binding
2.43 9.31e-03 GO:0003714 transcription corepressor activity
1.49 1.46e-02 GO:0001071 nucleic acid binding transcription factor activity
1.49 1.46e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 2.70e-02 GO:0019899 enzyme binding
2.88 3.94e-02 GO:0003729 mRNA binding