Motif ID: SREBF1,2.p2

Z-value: 1.318


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SREBF1chr17_-_17726855-0.082.3e-01Click!
SREBF2chr22_+_422291070.036.1e-01Click!


Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113951537 58.019 LAMP1
lysosomal-associated membrane protein 1
chr13_+_113951589 55.313 LAMP1
lysosomal-associated membrane protein 1
chr13_+_113951461 52.717 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr19_+_40854529 35.401 PLD3
phospholipase D family, member 3
chr19_+_40854331 34.774 NM_001031696
NM_012268
PLD3

phospholipase D family, member 3

chr17_+_78075299 28.528 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr17_+_78075390 27.735 GAA
glucosidase, alpha; acid
chr20_+_44520021 27.387 CTSA
cathepsin A
chr8_-_54755836 25.560 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr8_-_54755821 25.532 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr20_+_44519965 24.564 CTSA
cathepsin A
chr8_-_54755546 23.497 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr19_-_48018163 23.428 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr15_-_72668301 23.213 NM_000520
HEXA
hexosaminidase A (alpha polypeptide)
chr1_+_44440595 22.851 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr16_-_67514989 22.478 NM_004691
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr1_+_44440623 22.396 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr20_+_44519590 22.109 NM_000308
NM_001127695
NM_001167594
CTSA


cathepsin A


chr11_-_6640644 22.066 TPP1
tripeptidyl peptidase I
chr1_+_44440642 21.583 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr15_-_73925555 21.490 NPTN
neuroplastin
chr10_-_73610958 21.307 PSAP
prosaposin
chr10_-_73611005 20.695 PSAP
prosaposin
chr20_+_44519924 20.439 CTSA
cathepsin A
chr5_-_172198160 20.336 NM_004417
DUSP1
dual specificity phosphatase 1
chr11_-_1785126 20.069 CTSD
cathepsin D
chr10_+_51827710 19.721 FAM21A
family with sequence similarity 21, member A
chr15_-_73925658 19.685 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr12_-_65153182 18.981 GNS
glucosamine (N-acetyl)-6-sulfatase
chr3_+_113465910 18.569 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_+_113465860 18.501 NM_001690
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr16_-_1525020 18.364 CLCN7
chloride channel 7
chr15_-_72668184 17.951 HEXA
hexosaminidase A (alpha polypeptide)
chr19_-_48018317 17.945 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_44440673 17.920 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr11_-_6640578 17.221 TPP1
tripeptidyl peptidase I
chr19_+_7587436 17.018 NM_020533
MCOLN1
mucolipin 1
chrX_+_101380659 16.948 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr2_+_220042948 16.934 FAM134A
family with sequence similarity 134, member A
chr12_-_65153189 16.763 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr9_+_115913266 16.692 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr16_+_2570322 16.608 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr11_-_1785104 16.547 CTSD
cathepsin D
chr9_+_115913227 16.456 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr19_-_48018277 16.375 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr11_-_6640645 16.245 TPP1
tripeptidyl peptidase I
chr3_+_158519911 15.754 MFSD1
major facilitator superfamily domain containing 1
chr2_+_228189919 15.423 MFF
mitochondrial fission factor
chr5_-_150537261 15.319 ANXA6
annexin A6
chr2_+_220042986 15.250 FAM134A
family with sequence similarity 134, member A
chr6_-_33386064 15.216 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr3_+_158519888 14.670 MFSD1
major facilitator superfamily domain containing 1
chr19_-_10764449 14.621 LOC147727
uncharacterized LOC147727
chr11_-_1785087 14.521 CTSD
cathepsin D
chr5_-_150537306 14.502 ANXA6
annexin A6
chr20_-_39317875 14.433 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_154531083 13.920 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr11_+_121322848 13.911 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_44520203 13.868 CTSA
cathepsin A
chr18_+_9708187 13.818 NM_006868
RAB31
RAB31, member RAS oncogene family
chr18_+_9708269 13.687 RAB31
RAB31, member RAS oncogene family
chrX_+_102470003 13.660 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr3_+_158519714 13.635 NM_001167903
NM_022736
MFSD1

major facilitator superfamily domain containing 1

chr17_-_35969401 13.619 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr22_+_35695872 13.404 TOM1
target of myb1 (chicken)
chr16_-_1525006 13.347 CLCN7
chloride channel 7
chr1_+_110162427 13.294 NM_139156
AMPD2
adenosine monophosphate deaminase 2
chr18_+_9708322 13.286 RAB31
RAB31, member RAS oncogene family
chr3_+_112280871 13.159 NM_017945
SLC35A5
solute carrier family 35, member A5
chr3_+_158519877 13.135 MFSD1
major facilitator superfamily domain containing 1
chr3_+_158519925 13.116 MFSD1
major facilitator superfamily domain containing 1
chrX_+_100663229 13.047 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_65153148 12.927 GNS
glucosamine (N-acetyl)-6-sulfatase
chrX_+_100663120 12.838 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr1_+_110162459 12.695 AMPD2
adenosine monophosphate deaminase 2
chr3_+_128445024 12.619 RAB7A
RAB7A, member RAS oncogene family
chr1_-_40562909 12.462 PPT1
palmitoyl-protein thioesterase 1
chr16_+_85061303 12.429 NM_014732
KIAA0513
KIAA0513
chr16_-_5083913 12.423 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr10_+_51827654 12.412 NM_001005751
FAM21C
FAM21A
family with sequence similarity 21, member C
family with sequence similarity 21, member A
chr1_-_40562917 12.381 PPT1
palmitoyl-protein thioesterase 1
chr16_-_5083933 12.353 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_+_1067293 12.193 HMHA1
histocompatibility (minor) HA-1
chr10_+_46222647 12.170 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr16_-_1525040 12.142 NM_001114331
NM_001287
CLCN7

chloride channel 7

chr18_-_29523087 12.092 NM_014939
TRAPPC8
trafficking protein particle complex 8
chr1_-_1167421 11.904 NM_016176
NM_016547
SDF4

stromal cell derived factor 4

chr8_-_17941598 11.889 ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr10_-_73611041 11.885 PSAP
prosaposin
chr1_-_154928564 11.795 NM_020524
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr8_-_11725509 11.396 CTSB
cathepsin B
chr11_+_118938473 11.212 NM_021729
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_-_241520384 11.205 RGS7
regulator of G-protein signaling 7
chr2_-_197036262 11.161 STK17B
serine/threonine kinase 17b
chr16_-_88923233 10.854 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr1_-_241520467 10.819 NM_002924
RGS7
regulator of G-protein signaling 7
chrX_+_100663205 10.797 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr10_-_73611050 10.766 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr4_-_15656944 10.735 FBXL5
F-box and leucine-rich repeat protein 5
chr11_-_85780088 10.656 PICALM
phosphatidylinositol binding clathrin assembly protein
chr3_+_112280911 10.620 SLC35A5
solute carrier family 35, member A5
chr17_-_76124767 10.526 TMC6
transmembrane channel-like 6
chr11_+_118938528 10.502 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr12_+_12869818 10.382 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr8_-_17941614 10.301 ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr1_-_39325317 10.299 NM_022157
RRAGC
Ras-related GTP binding C
chr22_-_39268230 10.284 NM_014292
CBX6
chromobox homolog 6
chr11_+_118938515 10.133 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_-_150537335 9.930 NM_001155
ANXA6
annexin A6
chr9_+_6757636 9.851 NM_001146694
NM_001146695
NM_015061
KDM4C


lysine (K)-specific demethylase 4C


chr7_-_30029284 9.835 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr22_+_35695792 9.782 NM_001135730
NM_001135732
NM_005488
TOM1


target of myb1 (chicken)


chr20_-_36156226 9.665 BLCAP
bladder cancer associated protein
chr15_-_72668740 9.586 HEXA
hexosaminidase A (alpha polypeptide)
chr16_-_28503622 9.554 NM_001042432
CLN3
ceroid-lipofuscinosis, neuronal 3
chr11_+_118938530 9.516 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr16_-_15736964 9.439 NM_001184998
NM_001184999
NM_014647
KIAA0430


KIAA0430


chr1_+_11866240 9.428 CLCN6
chloride channel 6
chr3_+_113465901 9.393 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chrX_+_103031797 9.118 PLP1
proteolipid protein 1
chr22_-_21213069 9.104 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr22_-_21213099 8.985 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr16_+_87425946 8.985 MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr22_-_21213012 8.924 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr14_+_96505566 8.707 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr11_-_6640661 8.640 NM_000391
TPP1
tripeptidyl peptidase I
chr20_-_4795768 8.631 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr20_-_36156282 8.619 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr8_-_11725622 8.580 CTSB
cathepsin B
chr13_-_50159706 8.553 NM_018191
RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr2_+_220042901 8.516 NM_024293
FAM134A
family with sequence similarity 134, member A
chr15_+_89182038 8.503 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_42422627 8.480 GRN
granulin
chr16_+_19567021 8.469 C16orf62
chromosome 16 open reading frame 62
chr19_+_1067536 8.454 HMHA1
histocompatibility (minor) HA-1
chr20_-_36156082 8.450 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr12_+_51632620 8.423 DAZAP2
DAZ associated protein 2
chr9_+_117349993 8.290 NM_004888
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr13_-_50159628 8.279 RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chrX_-_15872921 8.275 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr12_-_65153055 8.263 GNS
glucosamine (N-acetyl)-6-sulfatase
chr12_+_51632654 8.216 DAZAP2
DAZ associated protein 2
chr1_-_154600383 8.167 ADAR
adenosine deaminase, RNA-specific
chr6_+_160390128 8.107 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr19_+_50016500 8.078 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_-_4508939 8.062 SUMF1
sulfatase modifying factor 1
chr3_+_128444978 8.035 NM_004637
RAB7A
RAB7A, member RAS oncogene family
chr6_-_33385662 8.018 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr16_+_2564000 7.993 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_50016490 7.948 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chrX_+_103031753 7.944 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_+_51632507 7.920 NM_001136264
NM_001136266
NM_001136267
NM_001136268
NM_001136269
NM_014764
DAZAP2





DAZ associated protein 2





chr12_+_112451151 7.913 NM_001034025
NM_006817
ERP29

endoplasmic reticulum protein 29

chrX_-_15872882 7.908 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr16_+_87425998 7.904 MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr18_+_9708299 7.889 RAB31
RAB31, member RAS oncogene family
chr22_+_35777087 7.868 HMOX1
heme oxygenase (decycling) 1
chr12_+_51632589 7.808 DAZAP2
DAZ associated protein 2
chr1_-_1167358 7.742 SDF4
stromal cell derived factor 4
chr16_+_87425874 7.695 MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr12_-_109027654 7.688 NM_003006
SELPLG
selectin P ligand
chr7_+_151722774 7.661 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr20_+_57428035 7.644 NM_001077490
NM_080425
GNAS

GNAS complex locus

chr12_+_6833425 7.605 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chrX_-_15872938 7.597 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr16_+_2563993 7.536 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_+_25621141 7.435 WSB1
WD repeat and SOCS box containing 1
chr7_+_149570004 7.432 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chrX_+_153656977 7.431 NM_001183
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chrX_-_15872905 7.421


chrX_+_153657025 7.415 ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr8_-_11725595 7.401 CTSB
cathepsin B
chr11_-_1785190 7.356 NM_001909
CTSD
cathepsin D
chr3_+_5021096 7.332 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr9_-_123476578 7.296 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr16_+_2563914 7.274 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_18208596 7.271 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr8_-_11725587 7.248 CTSB
cathepsin B
chr16_+_2563977 7.238 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chrX_+_153657119 7.236 ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr8_+_26240522 7.193 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr12_-_109027565 7.177 SELPLG
selectin P ligand
chr6_+_138188352 7.125 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_-_85780105 7.083 NM_001008660
NM_001206946
NM_007166
PICALM


phosphatidylinositol binding clathrin assembly protein


chr16_-_28503079 7.061 NM_000086
CLN3
ceroid-lipofuscinosis, neuronal 3
chr8_-_17941617 7.038 NM_177924
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr16_-_88923348 6.972 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr1_-_154928595 6.970 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chrX_-_13835313 6.932 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr7_+_108210308 6.929 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_+_42422490 6.908 NM_002087
GRN
granulin
chr19_+_1067114 6.881 NM_012292
HMHA1
histocompatibility (minor) HA-1
chr3_+_147127151 6.878 NM_003412
ZIC1
Zic family member 1
chr6_-_33385814 6.877


chr3_+_5021141 6.862 BHLHE40
basic helix-loop-helix family, member e40
chr16_+_11762235 6.777 NM_003498
SNN
stannin
chr7_+_151722842 6.765 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr13_+_42846255 6.669 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr11_+_65479472 6.663 NM_001206833
NM_006388
NM_182709
NM_182710
KAT5



K(lysine) acetyltransferase 5



chr14_-_74551159 6.647 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
9.04 2.08e-08 GO:0015682 ferric iron transport
9.04 2.08e-08 GO:0033572 transferrin transport
1.15 6.12e-07 GO:0009987 cellular process
7.84 4.85e-06 GO:0015988 energy coupled proton transport, against electrochemical gradient
7.84 4.85e-06 GO:0015991 ATP hydrolysis coupled proton transport
2.29 5.96e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.73 1.52e-05 GO:0033036 macromolecule localization
1.39 2.61e-05 GO:0051179 localization
5.12 3.52e-05 GO:0006818 hydrogen transport
4.79 4.35e-05 GO:0055072 iron ion homeostasis
1.96 4.86e-05 GO:0016192 vesicle-mediated transport
1.42 8.08e-05 GO:0051234 establishment of localization
1.42 9.95e-05 GO:0006810 transport
5.08 1.08e-04 GO:0006826 iron ion transport
3.45 1.12e-04 GO:0008286 insulin receptor signaling pathway
4.73 1.31e-04 GO:0006879 cellular iron ion homeostasis
4.99 1.41e-04 GO:0015992 proton transport
2.47 1.42e-04 GO:0071495 cellular response to endogenous stimulus
1.74 2.39e-04 GO:0008104 protein localization
1.24 2.55e-04 GO:0044237 cellular metabolic process
3.76 2.85e-04 GO:0000041 transition metal ion transport
1.97 3.79e-04 GO:0007167 enzyme linked receptor protein signaling pathway
5.27 4.39e-04 GO:0007033 vacuole organization
2.98 4.76e-04 GO:0032869 cellular response to insulin stimulus
1.65 6.45e-04 GO:0051641 cellular localization
2.66 1.49e-03 GO:0048011 nerve growth factor receptor signaling pathway
6.70 2.10e-03 GO:0007040 lysosome organization
1.76 3.25e-03 GO:0015031 protein transport
1.75 3.30e-03 GO:0045184 establishment of protein localization
2.33 3.45e-03 GO:0032870 cellular response to hormone stimulus
2.56 4.97e-03 GO:0071375 cellular response to peptide hormone stimulus
2.16 6.80e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.63 7.63e-03 GO:0051649 establishment of localization in cell
2.03 9.83e-03 GO:0016044 cellular membrane organization
1.82 1.11e-02 GO:0009719 response to endogenous stimulus
2.02 1.12e-02 GO:0061024 membrane organization
1.18 1.26e-02 GO:0008152 metabolic process
1.90 1.53e-02 GO:0019725 cellular homeostasis
2.44 1.90e-02 GO:0032868 response to insulin stimulus
1.83 2.17e-02 GO:0009725 response to hormone stimulus
1.20 2.29e-02 GO:0044238 primary metabolic process
3.90 2.30e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
2.15 2.45e-02 GO:0043434 response to peptide hormone stimulus
1.80 2.57e-02 GO:0071310 cellular response to organic substance
2.37 3.25e-02 GO:0006897 endocytosis
2.37 3.25e-02 GO:0010324 membrane invagination
1.43 3.27e-02 GO:0048583 regulation of response to stimulus
2.02 4.51e-02 GO:0007264 small GTPase mediated signal transduction
2.51 4.73e-02 GO:0034220 ion transmembrane transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.93 5.53e-20 GO:0005773 vacuole
1.32 6.37e-18 GO:0005737 cytoplasm
1.42 1.33e-16 GO:0044444 cytoplasmic part
4.73 6.16e-14 GO:0005774 vacuolar membrane
3.60 1.78e-13 GO:0000323 lytic vacuole
3.60 1.78e-13 GO:0005764 lysosome
4.52 3.33e-13 GO:0044437 vacuolar part
2.69 1.56e-10 GO:0005768 endosome
2.19 4.21e-10 GO:0031982 vesicle
2.19 1.08e-09 GO:0031410 cytoplasmic vesicle
2.22 1.64e-09 GO:0016023 cytoplasmic membrane-bounded vesicle
2.21 1.76e-09 GO:0031988 membrane-bounded vesicle
1.16 1.86e-09 GO:0005622 intracellular
1.16 5.03e-09 GO:0044424 intracellular part
10.85 2.49e-08 GO:0033176 proton-transporting V-type ATPase complex
4.28 3.48e-08 GO:0005765 lysosomal membrane
1.20 2.09e-07 GO:0043227 membrane-bounded organelle
1.20 2.58e-07 GO:0043231 intracellular membrane-bounded organelle
1.55 1.81e-06 GO:0005829 cytosol
3.71 8.05e-06 GO:0005770 late endosome
1.27 9.58e-06 GO:0044446 intracellular organelle part
1.27 1.13e-05 GO:0044422 organelle part
1.51 1.46e-05 GO:0031090 organelle membrane
1.16 1.87e-05 GO:0043226 organelle
1.16 1.97e-05 GO:0043229 intracellular organelle
2.56 1.17e-04 GO:0010008 endosome membrane
3.86 1.22e-04 GO:0042470 melanosome
3.86 1.22e-04 GO:0048770 pigment granule
5.47 1.26e-04 GO:0016469 proton-transporting two-sector ATPase complex
2.54 1.42e-04 GO:0044440 endosomal part
3.04 4.08e-04 GO:0005769 early endosome
15.07 1.11e-03 GO:0033179 proton-transporting V-type ATPase, V0 domain
1.80 7.65e-03 GO:0044431 Golgi apparatus part
2.58 1.06e-02 GO:0030136 clathrin-coated vesicle
7.03 1.10e-02 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain
4.02 1.17e-02 GO:0005798 Golgi-associated vesicle
1.56 1.79e-02 GO:0005794 Golgi apparatus
10.05 2.03e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
2.30 3.59e-02 GO:0030135 coated vesicle
9.04 3.88e-02 GO:0016471 vacuolar proton-transporting V-type ATPase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.30 2.02e-11 GO:0005515 protein binding
9.04 7.87e-05 GO:0046961 proton-transporting ATPase activity, rotational mechanism
1.10 1.21e-03 GO:0005488 binding
6.03 1.52e-03 GO:0019829 cation-transporting ATPase activity
1.91 8.62e-03 GO:0030695 GTPase regulator activity
3.67 1.12e-02 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
3.17 1.17e-02 GO:0015078 hydrogen ion transmembrane transporter activity
1.86 1.70e-02 GO:0060589 nucleoside-triphosphatase regulator activity