Motif ID: STAT2,4,6.p2

Z-value: 1.988


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT6chr12_-_57505176-0.314.4e-06Click!
STAT2chr12_-_567539160.188.6e-03Click!
STAT4chr2_-_192015733-0.136.1e-02Click!


Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_71502700 51.446 MAP1B
microtubule-associated protein 1B
chr14_+_95078713 39.281 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_9268522 32.247 NM_000014
A2M
alpha-2-macroglobulin
chr1_+_6845381 27.133 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr12_-_7245006 24.410 NM_001733
C1R
complement component 1, r subcomponent
chr12_-_7245048 24.165 C1R
complement component 1, r subcomponent
chr12_+_53443834 23.601 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_57365026 23.363 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_+_57365577 22.334 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr12_+_58138663 19.063 NM_005981
TSPAN31
tetraspanin 31
chr8_-_120651019 18.991 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr12_-_9268440 18.576 A2M
alpha-2-macroglobulin
chr1_+_155853546 18.465 SYT11
synaptotagmin XI
chr11_+_61197574 17.939 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr12_-_9268513 17.467 A2M
alpha-2-macroglobulin
chr11_-_12030128 17.077 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr3_+_159557745 16.909 SCHIP1
schwannomin interacting protein 1
chr1_-_230850335 16.583 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_+_133656984 15.707 NM_003440
ZNF140
zinc finger protein 140
chr1_-_230849863 15.647 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr15_+_71184781 15.582 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr4_-_176734181 15.428 NM_201591
GPM6A
glycoprotein M6A
chr17_+_32582295 15.137 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr3_+_133495925 14.366 TF
transferrin
chr12_-_9268475 14.169 A2M
alpha-2-macroglobulin
chr19_-_44123732 14.053 ZNF428
zinc finger protein 428
chr1_-_230849847 13.954 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr4_+_41258909 13.908 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_88896899 13.854 SPP1
secreted phosphoprotein 1
chr4_+_41258895 13.725 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258941 13.602 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_187463227 13.389 BCL6
B-cell CLL/lymphoma 6
chr10_-_90750955 13.203 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_12030622 13.179 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr4_+_88896868 13.120 SPP1
secreted phosphoprotein 1
chr20_+_44036940 13.011 DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_+_7167979 12.941 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr19_-_37019169 12.906 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr11_-_12030539 12.655 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr4_+_88896801 12.605 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr1_+_169075869 12.528 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_88896838 12.353 SPP1
secreted phosphoprotein 1
chr5_-_138210992 12.127 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr5_+_172483285 12.062 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr8_+_26371461 11.786 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr19_+_10381516 11.737 NM_000201
ICAM1
intercellular adhesion molecule 1
chr5_-_151066445 11.719 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_151066492 11.685 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr19_-_37407079 11.650 NM_001037232
ZNF829
zinc finger protein 829
chr8_+_26435920 11.495 NM_001244604
DPYSL2
dihydropyrimidinase-like 2
chr2_+_233498206 11.411 NM_025202
EFHD1
EF-hand domain family, member D1
chr8_-_144241918 11.399 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr5_+_140261792 11.350 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr19_+_10381763 11.180 ICAM1
intercellular adhesion molecule 1
chr11_+_73357222 11.072 NM_001130033
NM_021200
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr16_-_31085503 10.948 NM_024706
ZNF668
zinc finger protein 668
chr12_-_6798419 10.695 ZNF384
zinc finger protein 384
chr8_-_144241678 10.600 LY6H
lymphocyte antigen 6 complex, locus H
chr3_-_187463474 10.496 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr3_+_159557649 10.462 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr6_-_111136616 10.460 CDK19
cyclin-dependent kinase 19
chr19_-_44860798 10.364 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr9_+_74526527 10.263 C9orf85
chromosome 9 open reading frame 85
chr8_-_48650703 10.193 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr19_+_44669214 10.078 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr10_+_17851342 9.897 NM_002438
MRC1
mannose receptor, C type 1
chr8_-_48650683 9.781 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr13_+_111134933 9.693 COL4A2
collagen, type IV, alpha 2
chr9_-_89562103 9.658 NM_002048
GAS1
growth arrest-specific 1
chr19_+_44556163 9.596 NM_013361
ZNF223
zinc finger protein 223
chr1_+_171810611 9.582 NM_001136127
NM_015569
DNM3

dynamin 3

chr7_-_150038689 9.566 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr19_-_49339667 9.510 HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr22_-_30162990 9.491


chrX_-_13835313 9.490 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr5_+_40909558 9.429 NM_000587
C7
complement component 7
chr1_-_144994908 9.300 PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_42746743 9.295 GSK3A
glycogen synthase kinase 3 alpha
chr5_+_40909617 9.289 C7
complement component 7
chr19_+_45418063 9.237 APOC1
apolipoprotein C-I
chr19_+_15218141 9.158 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr1_-_144994839 9.151 PDE4DIP
phosphodiesterase 4D interacting protein
chr2_-_38303265 9.150 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr3_+_14166543 9.126 TMEM43
transmembrane protein 43
chr14_-_21270537 9.083 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr15_+_90808833 9.021 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr3_+_115342150 8.957 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr20_+_43991739 8.937 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr2_+_17935379 8.876 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr3_+_14166582 8.822 TMEM43
transmembrane protein 43
chrX_-_13835012 8.812 GPM6B
glycoprotein M6B
chr8_-_26371387 8.806 NM_007257
PNMA2
paraneoplastic antigen MA2
chr19_+_54024176 8.744 NM_018555
ZNF331
zinc finger protein 331
chr14_-_60097223 8.742 RTN1
reticulon 1
chrX_+_102632108 8.669 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr20_+_44036628 8.631 NM_001048225
NM_001048226
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr3_+_186330711 8.574 AHSG
alpha-2-HS-glycoprotein
chr18_+_29171729 8.500 NM_000371
TTR
transthyretin
chr16_+_56659584 8.470 NM_175617
MT1E
metallothionein 1E
chr1_-_144994943 8.464 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr16_+_53738044 8.445 FTO
fat mass and obesity associated
chr3_+_186330844 8.438 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr8_-_144241725 8.391 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr5_-_138211054 8.348 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_-_1619473 8.313 MIR22HG
MIR22 host gene (non-protein coding)
chr3_+_115342302 8.295 GAP43
growth associated protein 43
chr22_+_29138018 8.280 NM_172002
HSCB
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr19_-_44124013 8.195 NM_182498
ZNF428
zinc finger protein 428
chr12_+_13197284 8.194 NM_020853
KIAA1467
KIAA1467
chr7_+_86273951 8.192 GRM3
glutamate receptor, metabotropic 3
chr2_+_17935124 8.142 NM_182625
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr3_+_186330859 8.129 AHSG
alpha-2-HS-glycoprotein
chr17_-_29624249 8.093 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr19_+_44617510 8.089 NM_013362
ZNF225
zinc finger protein 225
chr7_-_37025696 8.020 ELMO1
engulfment and cell motility 1
chr11_+_114167168 7.869 NNMT
nicotinamide N-methyltransferase
chr3_+_14166439 7.864 NM_024334
TMEM43
transmembrane protein 43
chr15_-_71184611 7.813 NM_020147
THAP10
THAP domain containing 10
chr1_-_35497447 7.773 ZMYM6
zinc finger, MYM-type 6
chr10_+_88728187 7.726 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr19_+_57791281 7.725 ZNF460
zinc finger protein 460
chr19_+_40502942 7.678 NM_178544
ZNF546
zinc finger protein 546
chr3_-_50649080 7.653 CISH
cytokine inducible SH2-containing protein
chr16_+_67204404 7.646 NM_001185058
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr1_-_183274008 7.601 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr14_-_53417272 7.563 FERMT2
fermitin family member 2
chr19_-_42746678 7.535 GSK3A
glycogen synthase kinase 3 alpha
chr11_+_114167197 7.483 NNMT
nicotinamide N-methyltransferase
chr8_+_22462273 7.466 KIAA1967
KIAA1967
chr8_+_22462267 7.449 KIAA1967
KIAA1967
chr6_-_28304151 7.447 NM_001243241
NM_001243242
NM_001243244
NM_030899
ZNF323



zinc finger protein 323



chrX_-_48900932 7.420 NM_006521
TFE3
transcription factor binding to IGHM enhancer 3
chr1_+_36690038 7.395 THRAP3
thyroid hormone receptor associated protein 3
chr19_-_49339913 7.389 NM_016246
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr12_+_12938540 7.387 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr7_+_86274076 7.381 GRM3
glutamate receptor, metabotropic 3
chr4_-_155511838 7.375 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr13_-_36705432 7.329 DCLK1
doublecortin-like kinase 1
chr4_+_41362750 7.313 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr3_+_133464883 7.299 NM_001063
TF
transferrin
chr8_-_110661007 7.297 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_+_36689996 7.251 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr11_-_117186918 7.240 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chr1_+_155099935 7.233 EFNA1
ephrin-A1
chr16_+_31085751 7.197 ZNF646
zinc finger protein 646
chr8_-_27472188 7.186 CLU
clusterin
chr16_-_28550227 7.185 NUPR1
nuclear protein, transcriptional regulator, 1
chr16_+_56659679 7.165 MT1E
metallothionein 1E
chrX_-_48931645 7.121 NM_007213
PRAF2
PRA1 domain family, member 2
chr7_+_86273219 7.094 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr16_+_53737874 7.071 NM_001080432
FTO
fat mass and obesity associated
chr8_+_22462286 7.034 KIAA1967
KIAA1967
chr19_-_36980758 6.984 ZNF566
zinc finger protein 566
chr4_-_155533882 6.928 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr4_-_155533757 6.895 FGG
fibrinogen gamma chain
chr8_+_1952875 6.860 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_-_35497544 6.852 ZMYM6
zinc finger, MYM-type 6
chr12_-_93964636 6.851


chr6_+_31913763 6.822 CFB
complement factor B
chr14_-_105715740 6.798 NM_001242789
BRF1
BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
chr16_+_31085722 6.698 NM_014699
ZNF646
zinc finger protein 646
chr8_+_26435466 6.695 DPYSL2
dihydropyrimidinase-like 2
chr14_-_60097531 6.687 NM_206852
RTN1
reticulon 1
chr8_-_95274520 6.660 GEM
GTP binding protein overexpressed in skeletal muscle
chr9_-_130186491 6.632


chr4_-_88450601 6.586 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr19_-_42746723 6.526 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chr5_-_140013034 6.464 NM_000591
CD14
CD14 molecule
chr8_-_27472298 6.450 NM_001831
CLU
clusterin
chr16_-_28550324 6.449 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr3_-_139108486 6.449


chr17_-_42992852 6.441 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr4_-_155533850 6.440 FGG
fibrinogen gamma chain
chr19_+_48867650 6.402 NM_012451
SYNGR4
synaptogyrin 4
chr11_+_73358593 6.398 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr8_-_22089850 6.391 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr16_-_56701904 6.387 NM_005950
MT1G
metallothionein 1G
chr17_+_40834571 6.378 NM_003632
CNTNAP1
contactin associated protein 1
chr1_+_54519259 6.358 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr12_-_45269340 6.352 NM_001145109
NELL2
NEL-like 2 (chicken)
chr2_+_79347487 6.333 NM_002909
REG1A
regenerating islet-derived 1 alpha
chr14_+_94577078 6.333 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr17_+_76183397 6.329 NM_001010982
NM_001145526
AFMID

arylformamidase

chr5_-_140013285 6.297 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr1_-_35497563 6.292 NM_007167
ZMYM6
zinc finger, MYM-type 6
chr13_-_36705513 6.288 NM_004734
DCLK1
doublecortin-like kinase 1
chr4_-_155533800 6.285 FGG
fibrinogen gamma chain
chr2_+_17721806 6.279 NM_003385
VSNL1
visinin-like 1
chr8_+_22462532 6.274 NM_021174
KIAA1967
KIAA1967
chr2_+_31456879 6.272 NM_014600
EHD3
EH-domain containing 3
chr6_-_28303910 6.262 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr1_-_156217717 6.243 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr17_+_74733468 6.242 NM_001242532
NM_001242533
NM_001242535
NM_001242536
NM_001242537
NM_024311
MFSD11





major facilitator superfamily domain containing 11





chr3_+_45067750 6.214 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr11_-_72380107 6.203 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_-_163113938 6.194 RGS5
regulator of G-protein signaling 5
chr2_+_201450730 6.187 NM_001159
AOX1
aldehyde oxidase 1
chr12_-_6798528 6.186 NM_133476
ZNF384
zinc finger protein 384
chr12_-_6798619 6.170 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr19_+_56652689 6.163 ZNF444
zinc finger protein 444

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 2.83e-18 GO:0065007 biological regulation
1.22 2.77e-13 GO:0050789 regulation of biological process
1.34 7.56e-11 GO:0023052 signaling
1.21 2.20e-10 GO:0050794 regulation of cellular process
1.43 3.30e-08 GO:0065008 regulation of biological quality
1.32 5.56e-08 GO:0007165 signal transduction
1.51 1.84e-07 GO:0007399 nervous system development
1.65 7.66e-07 GO:0009611 response to wounding
1.10 1.27e-06 GO:0009987 cellular process
1.65 2.01e-06 GO:0040011 locomotion
1.42 2.23e-06 GO:0048583 regulation of response to stimulus
1.87 2.42e-06 GO:0048858 cell projection morphogenesis
1.86 3.93e-06 GO:0032990 cell part morphogenesis
1.51 4.25e-06 GO:0051239 regulation of multicellular organismal process
1.71 5.05e-06 GO:0030182 neuron differentiation
1.26 8.84e-06 GO:0032502 developmental process
1.18 9.59e-06 GO:0050896 response to stimulus
1.24 1.32e-05 GO:0051716 cellular response to stimulus
1.88 1.38e-05 GO:0048812 neuron projection morphogenesis
1.75 1.72e-05 GO:0000902 cell morphogenesis
1.76 1.72e-05 GO:0048666 neuron development
1.28 2.44e-05 GO:0048856 anatomical structure development
1.89 2.44e-05 GO:0007409 axonogenesis
1.20 3.30e-05 GO:0032501 multicellular organismal process
1.26 4.20e-05 GO:0007275 multicellular organismal development
1.81 4.28e-05 GO:0031175 neuron projection development
1.30 5.14e-05 GO:0048731 system development
1.57 5.23e-05 GO:0022008 neurogenesis
1.79 7.47e-05 GO:0000904 cell morphogenesis involved in differentiation
1.53 8.70e-05 GO:0009605 response to external stimulus
1.68 9.15e-05 GO:0030030 cell projection organization
1.23 1.06e-04 GO:0019222 regulation of metabolic process
1.83 1.32e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.61 1.34e-04 GO:0007155 cell adhesion
1.61 1.34e-04 GO:0022610 biological adhesion
1.33 1.43e-04 GO:0042221 response to chemical stimulus
1.67 1.57e-04 GO:0032989 cellular component morphogenesis
1.39 1.74e-04 GO:0023051 regulation of signaling
1.29 2.26e-04 GO:0048518 positive regulation of biological process
1.73 3.30e-04 GO:0006935 chemotaxis
1.73 3.30e-04 GO:0042330 taxis
1.52 4.73e-04 GO:0048468 cell development
1.30 5.50e-04 GO:0006950 response to stress
1.54 6.21e-04 GO:0048699 generation of neurons
1.40 6.37e-04 GO:0009653 anatomical structure morphogenesis
1.56 1.60e-03 GO:0007267 cell-cell signaling
1.39 2.57e-03 GO:0035556 intracellular signal transduction
1.38 3.64e-03 GO:0009966 regulation of signal transduction
1.22 4.00e-03 GO:0080090 regulation of primary metabolic process
1.26 4.07e-03 GO:0009889 regulation of biosynthetic process
1.26 5.03e-03 GO:0031326 regulation of cellular biosynthetic process
1.82 5.12e-03 GO:0007411 axon guidance
1.33 5.12e-03 GO:0007166 cell surface receptor linked signaling pathway
1.29 6.49e-03 GO:0048869 cellular developmental process
1.27 7.32e-03 GO:0048522 positive regulation of cellular process
1.50 7.80e-03 GO:0048584 positive regulation of response to stimulus
1.21 7.86e-03 GO:0031323 regulation of cellular metabolic process
1.82 8.14e-03 GO:0051050 positive regulation of transport
1.29 1.12e-02 GO:0030154 cell differentiation
1.21 1.40e-02 GO:0060255 regulation of macromolecule metabolic process
3.60 1.58e-02 GO:0006953 acute-phase response
1.44 1.70e-02 GO:0042127 regulation of cell proliferation
5.93 2.81e-02 GO:0032835 glomerulus development
1.85 3.26e-02 GO:2000145 regulation of cell motility
1.90 3.53e-02 GO:0030168 platelet activation
1.66 3.82e-02 GO:0016477 cell migration
1.51 4.60e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.84 4.92e-02 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.53 2.47e-15 GO:0044459 plasma membrane part
1.62 1.14e-10 GO:0005887 integral to plasma membrane
1.60 4.20e-10 GO:0031226 intrinsic to plasma membrane
1.24 1.03e-06 GO:0005886 plasma membrane
1.24 1.34e-06 GO:0071944 cell periphery
1.59 1.46e-05 GO:0005615 extracellular space
1.51 1.50e-05 GO:0044421 extracellular region part
2.02 2.34e-04 GO:0016323 basolateral plasma membrane
1.30 3.28e-04 GO:0005576 extracellular region
1.57 1.33e-03 GO:0030054 cell junction
1.76 6.57e-03 GO:0044456 synapse part
1.63 1.04e-02 GO:0045202 synapse
2.33 1.17e-02 GO:0005925 focal adhesion
2.03 1.87e-02 GO:0005912 adherens junction
2.22 2.13e-02 GO:0030055 cell-substrate junction
1.92 2.49e-02 GO:0030424 axon
2.22 2.91e-02 GO:0005924 cell-substrate adherens junction
1.60 3.75e-02 GO:0031012 extracellular matrix
1.58 4.04e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 2.63e-06 GO:0005488 binding
1.55 3.25e-06 GO:0005102 receptor binding
1.14 5.14e-05 GO:0005515 protein binding
1.19 1.85e-03 GO:0043167 ion binding
1.19 2.38e-03 GO:0043169 cation binding
1.19 3.18e-03 GO:0046872 metal ion binding
1.51 5.53e-03 GO:0005509 calcium ion binding
3.81 1.76e-02 GO:0005158 insulin receptor binding
2.96 1.96e-02 GO:0003707 steroid hormone receptor activity
1.37 4.16e-02 GO:0001071 nucleic acid binding transcription factor activity
1.37 4.16e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.80 4.51e-02 GO:0004879 ligand-dependent nuclear receptor activity