Motif ID: TFCP2.p2

Z-value: 2.812


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFCP2chr12_-_51566555-0.188.6e-03Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_137967088 47.245 NM_014279
NM_006334
OLFM1

olfactomedin 1

chr5_+_134240820 43.618 PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr5_+_134240752 41.990 NM_032151
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr9_+_137967366 39.774 OLFM1
olfactomedin 1
chrX_+_38420690 39.608 NM_004615
TSPAN7
tetraspanin 7
chr9_+_137967401 36.727 OLFM1
olfactomedin 1
chr10_+_124220990 31.938 NM_002775
HTRA1
HtrA serine peptidase 1
chrX_-_106960028 31.907 TSC22D3
TSC22 domain family, member 3
chr11_-_2159784 31.575 IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_+_33685140 30.558 LRP3
low density lipoprotein receptor-related protein 3
chr16_+_58498216 29.974 NDRG4
NDRG family member 4
chr16_+_58498182 29.568 NDRG4
NDRG family member 4
chr22_+_23229959 29.527 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr17_-_56609361 29.011 SEPT4
septin 4
chr14_-_21493122 28.027 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr9_-_139094886 28.015 NM_014564
LHX3
LIM homeobox 3
chrX_-_106960268 27.857 NM_004089
TSC22D3
TSC22 domain family, member 3
chr9_+_137967267 27.788 OLFM1
olfactomedin 1
chr9_+_35605275 27.302 NM_006285
TESK1
testis-specific kinase 1
chr5_+_175792444 27.263 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr4_-_8873453 27.065 NM_018942
HMX1
H6 family homeobox 1
chr9_+_35605339 26.873 TESK1
testis-specific kinase 1
chr16_+_2588000 26.799 PDPK1
3-phosphoinositide dependent protein kinase-1
chr3_+_133465098 26.061 TF
transferrin
chr16_+_58497993 25.899 NM_001130487
NDRG4
NDRG family member 4
chr13_-_36705432 25.806 DCLK1
doublecortin-like kinase 1
chr16_+_2587989 25.454 PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_55464605 25.421 NM_057176
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr1_+_46269283 24.157 NM_015112
MAST2
microtubule associated serine/threonine kinase 2
chr9_+_139560243 23.968 EGFL7
EGF-like-domain, multiple 7
chr16_+_2588021 23.715 PDPK1
3-phosphoinositide dependent protein kinase-1
chr17_+_8339135 23.610 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr3_+_133465250 23.506 TF
transferrin
chr19_+_33685489 23.387 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr7_-_150038689 23.034 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr17_+_18128868 22.834 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr7_-_98741605 22.726 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr9_+_139560193 22.561 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr3_-_47620186 22.399 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr20_-_3154169 21.961 ProSAPiP1
ProSAPiP1 protein
chr7_-_129251465 21.906


chr9_+_35605614 21.277 TESK1
testis-specific kinase 1
chr7_-_99756329 21.120 C7orf43
chromosome 7 open reading frame 43
chr5_-_693413 21.017 NM_007030
TPPP
tubulin polymerization promoting protein
chr1_+_183605207 20.886 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr5_-_176057324 20.565 NM_001001502
NM_003085
SNCB

synuclein, beta

chr20_+_19193282 20.444 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr10_-_105452878 19.941 SH3PXD2A
SH3 and PX domains 2A
chr9_-_110251754 19.821 KLF4
Kruppel-like factor 4 (gut)
chr9_-_110252045 19.719 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr13_-_28674646 19.541 NM_004119
FLT3
fms-related tyrosine kinase 3
chr19_+_3178735 19.460 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr16_+_2653350 19.313 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr15_+_62682682 19.299 TLN2
talin 2
chr17_-_73511626 19.269 NM_020753
CASKIN2
CASK interacting protein 2
chr17_-_4693595 19.210 LOC284014
uncharacterized LOC284014
chr5_+_76506705 19.131 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr17_-_73511453 18.886 CASKIN2
CASK interacting protein 2
chr22_-_39548448 18.882 NM_175709
CBX7
chromobox homolog 7
chr9_-_115480363 18.841 NM_021218
C9orf80
chromosome 9 open reading frame 80
chr4_+_4388717 18.715 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr19_-_4457789 18.532 NM_025241
UBXN6
UBX domain protein 6
chr4_+_187112936 18.336 CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr17_-_56609387 18.264 NM_080415
NM_080416
SEPT4

septin 4

chr17_+_59477473 18.165 TBX2
T-box 2
chr8_+_136469557 18.071 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr16_+_15528324 17.977 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr5_+_140306301 17.897 NM_018898
NM_031882
PCDHAC1

protocadherin alpha subfamily C, 1

chr9_+_35605449 17.555 TESK1
testis-specific kinase 1
chr2_-_95825504 17.522 ZNF514
zinc finger protein 514
chr14_+_101193313 17.507 DLK1
delta-like 1 homolog (Drosophila)
chr11_+_73357222 17.392 NM_001130033
NM_021200
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr6_+_31783530 17.196 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr10_-_73611041 16.953 PSAP
prosaposin
chr2_-_87017948 16.930 CD8A
CD8a molecule
chr1_-_11714738 16.796 NM_012168
FBXO2
F-box protein 2
chr5_-_115910406 16.697 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_+_41223282 16.670 ITPKC
inositol-trisphosphate 3-kinase C
chr19_+_33182689 16.564 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr8_+_38034296 16.464 BAG4
BCL2-associated athanogene 4
chr4_+_187112635 16.387 NM_207352
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr3_+_133464883 16.183 NM_001063
TF
transferrin
chr7_-_35734728 16.092 HERPUD2
HERPUD family member 2
chr14_-_60337350 16.063 NM_021136
RTN1
reticulon 1
chr4_+_76439653 16.044 NM_144721
THAP6
THAP domain containing 6
chr13_+_31191829 16.032 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr19_+_35629727 16.025 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr14_+_69726868 15.983 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr1_-_17445865 15.960 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr21_-_33104210 15.953 SCAF4
SR-related CTD-associated factor 4
chr16_+_22825481 15.948 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_44412418 15.925 NM_014652
IPO13
importin 13
chr5_-_1634099 15.836 LOC728613
programmed cell death 6 pseudogene
chr18_+_21594349 15.758 NM_001135993
NM_001243425
TTC39C

tetratricopeptide repeat domain 39C

chr7_-_35734472 15.722 HERPUD2
HERPUD family member 2
chr10_-_73611005 15.671 PSAP
prosaposin
chr19_+_40973049 15.550 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr2_-_87018066 15.523 CD8A
CD8a molecule
chr10_-_128077062 15.358 ADAM12
ADAM metallopeptidase domain 12
chr11_-_61684981 15.308 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr3_+_52529351 15.184 NM_015136
STAB1
stabilin 1
chr10_-_73610958 15.128 PSAP
prosaposin
chrX_+_43514157 15.099 MAOA
monoamine oxidase A
chr1_-_156217717 15.035 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr14_+_100150596 15.007 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr16_+_3254246 14.905 NM_012360
OR1F1
olfactory receptor, family 1, subfamily F, member 1
chr9_+_123963728 14.901 GSN
gelsolin
chr11_+_117070039 14.794 NM_001001522
NM_003186
TAGLN

transgelin

chr15_+_31619043 14.782 NM_015995
KLF13
Kruppel-like factor 13
chr2_-_11484699 14.727 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr7_-_64023444 14.691


chr19_-_33793429 14.611 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr8_+_24772454 14.589 NM_001105541
NEFM
neurofilament, medium polypeptide
chr4_+_166299942 14.524 NM_001873
CPE
carboxypeptidase E
chr7_-_99756275 14.470 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr19_+_16435632 14.409 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr3_+_52529370 14.338 STAB1
stabilin 1
chr6_+_42531767 14.310 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr19_-_58609606 14.232 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr2_+_242641310 14.202 NM_032329
ING5
inhibitor of growth family, member 5
chr17_-_34891262 14.166 NM_001033580
NM_001163735
NM_025109
MYO19


myosin XIX


chr19_+_58361219 14.157 ZNF587
zinc finger protein 587
chr8_+_11142314 14.149 MTMR9
myotubularin related protein 9
chr9_+_124030370 14.115 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
GSN






gelsolin






chr14_-_103989112 14.082 CKB
creatine kinase, brain
chr14_+_101292483 14.046


chr14_-_52535737 14.039 NID2
nidogen 2 (osteonidogen)
chr12_+_66218879 13.955 HMGA2
high mobility group AT-hook 2
chr19_+_49956472 13.869 NM_001145396
NM_153329
ALDH16A1

aldehyde dehydrogenase 16 family, member A1

chr2_+_85360373 13.641 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr4_+_4388804 13.598 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr3_+_49449638 13.474 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr17_-_40021616 13.474 NM_018143
KLHL11
kelch-like 11 (Drosophila)
chr13_-_36705513 13.394 NM_004734
DCLK1
doublecortin-like kinase 1
chr17_+_1665281 13.332 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_-_113161724 13.328 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr2_+_242295660 13.312 NM_014808
FARP2
FERM, RhoGEF and pleckstrin domain protein 2
chr19_-_2236648 13.276 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr1_+_44412582 13.276 IPO13
importin 13
chr1_+_44412640 13.258 IPO13
importin 13
chr11_+_62104773 13.253 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr4_-_1166547 13.244 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr17_+_1665233 13.231 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_+_58497628 13.185 NDRG4
NDRG family member 4
chr19_+_39897457 13.126 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr14_-_107013474 13.107 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_71680752 13.087 NM_001130976
NM_001130977
NM_001130978
NM_001130979
NM_001130980
NM_001130981
NM_003494
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr7_+_35840595 13.080 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr17_+_1665306 13.057 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_+_101292451 12.985 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_61129831 12.940 TMEM138
transmembrane protein 138
chr19_+_36132646 12.901 NM_014209
ETV2
ets variant 2
chr11_+_120894756 12.852 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr1_-_177133950 12.844 NM_004319
NM_207108
ASTN1

astrotactin 1

chr16_+_2587951 12.841 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chrX_-_133119624 12.838 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr7_-_35734762 12.820 NM_022373
HERPUD2
HERPUD family member 2
chr3_-_14989399 12.815 LOC100505641
uncharacterized LOC100505641
chr20_-_17662704 12.811 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr11_+_129939667 12.810 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr7_-_111846384 12.717 NM_014705
DOCK4
dedicator of cytokinesis 4
chr11_-_2159925 12.705 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_133119475 12.569 GPC3
glypican 3
chr11_-_123612369 12.549 ZNF202
zinc finger protein 202
chr3_+_184032414 12.518 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr7_-_79082870 12.404 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_40254131 12.324 BMP8B
bone morphogenetic protein 8b
chr4_-_1166458 12.312 SPON2
spondin 2, extracellular matrix protein
chr10_-_73611050 12.283 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr17_+_1665342 12.261 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_-_98290072 12.255 TSPYL5
TSPY-like 5
chr11_+_65190272 12.246


chr3_-_194991778 12.238 NM_152531
XXYLT1
xyloside xylosyltransferase 1
chr10_-_128077011 12.152 ADAM12
ADAM metallopeptidase domain 12
chr14_+_96505566 12.125 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr7_-_44365019 12.106 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr19_-_14228362 12.087 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr13_+_48877950 12.086 RB1
retinoblastoma 1
chr12_-_51611476 12.084 POU6F1
POU class 6 homeobox 1
chr16_+_84002099 12.074 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr14_-_105767328 11.994 NM_001242788
NM_001242790
NM_001519
BRF1


BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)


chr6_+_43543921 11.989 POLH
polymerase (DNA directed), eta
chr15_+_68871285 11.989 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr15_-_23932410 11.989 NM_002487
NDN
necdin homolog (mouse)
chr14_-_107113943 11.965 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_+_58906968 11.912 NM_147189
FAM110B
family with sequence similarity 110, member B
chr3_+_183873305 11.869 DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr19_-_9929682 11.859 NM_017703
FBXL12
F-box and leucine-rich repeat protein 12
chr5_+_170736287 11.853 NM_021025
TLX3
T-cell leukemia homeobox 3
chr11_-_64512265 11.848 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_+_94023872 11.848 NM_000089
COL1A2
collagen, type I, alpha 2
chrX_-_40594774 11.822 NM_004229
MED14
mediator complex subunit 14
chr5_-_93447237 11.816 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr7_+_153584383 11.736 NM_001039350
DPP6
dipeptidyl-peptidase 6
chr16_-_1525020 11.683 CLCN7
chloride channel 7
chr13_+_96204941 11.654 NM_006984
CLDN10
claudin 10
chr8_-_145158665 11.561 SHARPIN
SHANK-associated RH domain interactor
chr2_+_220378891 11.511 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr15_-_75165595 11.492 NM_005697
SCAMP2
secretory carrier membrane protein 2
chr20_+_19193364 11.472 SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 1.23e-30 GO:0065007 biological regulation
1.24 1.26e-26 GO:0050789 regulation of biological process
1.24 8.10e-23 GO:0050794 regulation of cellular process
1.38 8.62e-23 GO:0023052 signaling
1.37 3.18e-17 GO:0048856 anatomical structure development
1.33 3.45e-17 GO:0032502 developmental process
1.46 3.37e-16 GO:0048869 cellular developmental process
1.38 1.09e-15 GO:0048731 system development
1.43 2.18e-15 GO:0042221 response to chemical stimulus
1.45 2.33e-15 GO:0030154 cell differentiation
1.33 3.45e-15 GO:0007275 multicellular organismal development
1.33 4.44e-15 GO:0007165 signal transduction
1.56 1.33e-13 GO:0051239 regulation of multicellular organismal process
1.51 2.19e-13 GO:0007399 nervous system development
1.39 2.99e-13 GO:0048519 negative regulation of biological process
1.66 4.80e-13 GO:0050793 regulation of developmental process
1.27 5.63e-13 GO:0051716 cellular response to stimulus
1.40 1.69e-12 GO:0065008 regulation of biological quality
1.44 2.56e-12 GO:0007166 cell surface receptor linked signaling pathway
1.40 3.02e-12 GO:0048523 negative regulation of cellular process
1.22 4.38e-12 GO:0032501 multicellular organismal process
1.69 3.29e-11 GO:2000026 regulation of multicellular organismal development
1.41 6.38e-11 GO:0048583 regulation of response to stimulus
1.10 7.07e-11 GO:0009987 cellular process
1.44 1.48e-10 GO:0023051 regulation of signaling
1.19 1.55e-10 GO:0050896 response to stimulus
1.50 2.20e-10 GO:0010033 response to organic substance
1.45 4.06e-10 GO:0009653 anatomical structure morphogenesis
1.56 7.02e-10 GO:0032879 regulation of localization
1.70 8.06e-10 GO:0007167 enzyme linked receptor protein signaling pathway
1.56 1.12e-09 GO:0042127 regulation of cell proliferation
2.02 2.83e-09 GO:0022603 regulation of anatomical structure morphogenesis
1.24 3.39e-09 GO:0019222 regulation of metabolic process
1.56 4.58e-09 GO:0022008 neurogenesis
1.58 7.68e-09 GO:0048699 generation of neurons
1.25 1.02e-08 GO:0080090 regulation of primary metabolic process
1.43 1.45e-08 GO:0009966 regulation of signal transduction
1.25 1.60e-08 GO:0031323 regulation of cellular metabolic process
1.83 1.76e-08 GO:0008285 negative regulation of cell proliferation
1.63 4.53e-08 GO:0045595 regulation of cell differentiation
1.61 1.06e-07 GO:0030182 neuron differentiation
1.28 1.95e-07 GO:0048518 positive regulation of biological process
1.61 2.60e-07 GO:0009719 response to endogenous stimulus
1.34 3.35e-07 GO:0048513 organ development
1.40 8.30e-07 GO:0035556 intracellular signal transduction
1.68 9.19e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 9.95e-07 GO:0060255 regulation of macromolecule metabolic process
1.51 1.11e-06 GO:0040011 locomotion
1.47 1.20e-06 GO:0007154 cell communication
1.54 1.77e-06 GO:0007267 cell-cell signaling
1.28 1.80e-06 GO:0048522 positive regulation of cellular process
1.73 2.44e-06 GO:0007409 axonogenesis
1.72 2.84e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.66 5.27e-06 GO:0048858 cell projection morphogenesis
1.47 5.46e-06 GO:0048468 cell development
1.26 6.74e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 6.88e-06 GO:0009725 response to hormone stimulus
1.50 8.11e-06 GO:0051128 regulation of cellular component organization
1.64 9.61e-06 GO:0032990 cell part morphogenesis
1.58 1.24e-05 GO:0000902 cell morphogenesis
1.64 1.29e-05 GO:0000904 cell morphogenesis involved in differentiation
1.80 1.39e-05 GO:0051093 negative regulation of developmental process
1.51 1.69e-05 GO:0006468 protein phosphorylation
1.42 1.71e-05 GO:0010646 regulation of cell communication
1.59 1.84e-05 GO:0048666 neuron development
1.78 1.92e-05 GO:0032535 regulation of cellular component size
1.24 2.41e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.66 2.85e-05 GO:0051094 positive regulation of developmental process
1.25 3.13e-05 GO:0010468 regulation of gene expression
1.56 3.40e-05 GO:0009887 organ morphogenesis
1.66 3.57e-05 GO:0048812 neuron projection morphogenesis
1.24 3.66e-05 GO:0009889 regulation of biosynthetic process
1.54 4.88e-05 GO:0032989 cellular component morphogenesis
1.71 5.17e-05 GO:0090066 regulation of anatomical structure size
1.24 6.69e-05 GO:0031326 regulation of cellular biosynthetic process
1.75 7.07e-05 GO:0044057 regulation of system process
1.76 1.06e-04 GO:0060284 regulation of cell development
1.79 1.21e-04 GO:0051270 regulation of cellular component movement
1.52 1.31e-04 GO:0030030 cell projection organization
1.27 1.31e-04 GO:0006355 regulation of transcription, DNA-dependent
1.40 1.64e-04 GO:0006793 phosphorus metabolic process
1.40 1.64e-04 GO:0006796 phosphate metabolic process
1.26 2.18e-04 GO:0051252 regulation of RNA metabolic process
1.50 2.28e-04 GO:0010628 positive regulation of gene expression
1.41 2.54e-04 GO:0070887 cellular response to chemical stimulus
1.58 3.00e-04 GO:0031175 neuron projection development
1.80 3.58e-04 GO:0045596 negative regulation of cell differentiation
1.81 3.75e-04 GO:0008361 regulation of cell size
1.50 4.32e-04 GO:0001932 regulation of protein phosphorylation
1.77 4.44e-04 GO:0051960 regulation of nervous system development
1.80 4.52e-04 GO:0030334 regulation of cell migration
1.70 4.59e-04 GO:0007411 axon guidance
1.69 5.06e-04 GO:0043434 response to peptide hormone stimulus
1.57 5.52e-04 GO:0019226 transmission of nerve impulse
1.57 5.52e-04 GO:0035637 multicellular organismal signaling
1.58 6.63e-04 GO:0072358 cardiovascular system development
1.58 6.63e-04 GO:0072359 circulatory system development
1.60 6.64e-04 GO:0007268 synaptic transmission
1.78 7.87e-04 GO:2000145 regulation of cell motility
1.23 8.15e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.23 8.26e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.73 1.01e-03 GO:0040012 regulation of locomotion
1.60 1.04e-03 GO:0040008 regulation of growth
1.45 1.10e-03 GO:0051049 regulation of transport
1.47 1.12e-03 GO:0042325 regulation of phosphorylation
1.38 1.16e-03 GO:0009605 response to external stimulus
1.45 1.64e-03 GO:0019220 regulation of phosphate metabolic process
1.45 1.64e-03 GO:0051174 regulation of phosphorus metabolic process
1.59 1.69e-03 GO:0007243 intracellular protein kinase cascade
1.59 1.69e-03 GO:0023014 signal transduction via phosphorylation event
1.53 1.89e-03 GO:0006935 chemotaxis
1.53 1.89e-03 GO:0042330 taxis
1.41 2.16e-03 GO:0016310 phosphorylation
1.66 2.18e-03 GO:0045597 positive regulation of cell differentiation
1.30 2.98e-03 GO:0065009 regulation of molecular function
1.45 4.16e-03 GO:0071310 cellular response to organic substance
1.32 4.34e-03 GO:0002376 immune system process
1.35 8.10e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.67 8.66e-03 GO:0001944 vasculature development
1.94 8.88e-03 GO:0031344 regulation of cell projection organization
1.95 9.01e-03 GO:0001655 urogenital system development
1.80 9.18e-03 GO:0045664 regulation of neuron differentiation
1.45 9.41e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.55 1.08e-02 GO:0009968 negative regulation of signal transduction
1.57 1.17e-02 GO:0060429 epithelium development
1.53 1.24e-02 GO:0023057 negative regulation of signaling
1.52 1.39e-02 GO:0010648 negative regulation of cell communication
1.17 1.40e-02 GO:0051179 localization
1.37 1.42e-02 GO:0009888 tissue development
2.00 1.49e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.41 1.53e-02 GO:0051147 regulation of muscle cell differentiation
1.60 1.57e-02 GO:0071495 cellular response to endogenous stimulus
1.98 1.88e-02 GO:0022604 regulation of cell morphogenesis
1.62 1.99e-02 GO:0032870 cellular response to hormone stimulus
2.18 2.01e-02 GO:0001505 regulation of neurotransmitter levels
1.48 2.18e-02 GO:0048585 negative regulation of response to stimulus
1.48 2.30e-02 GO:0043549 regulation of kinase activity
1.69 2.33e-02 GO:0050767 regulation of neurogenesis
1.29 2.44e-02 GO:0009893 positive regulation of metabolic process
1.47 2.49e-02 GO:0007417 central nervous system development
2.40 2.65e-02 GO:0007269 neurotransmitter secretion
1.66 2.84e-02 GO:0001568 blood vessel development
2.07 2.95e-02 GO:0010720 positive regulation of cell development
1.30 3.15e-02 GO:0050790 regulation of catalytic activity
1.68 3.21e-02 GO:0000165 MAPKKK cascade
1.30 3.28e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.70 3.56e-02 GO:0032868 response to insulin stimulus
1.48 3.59e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.05 3.80e-02 GO:0006836 neurotransmitter transport
1.99 3.86e-02 GO:0007265 Ras protein signal transduction
1.51 4.00e-02 GO:0016477 cell migration
1.76 4.07e-02 GO:0048732 gland development
1.55 4.33e-02 GO:0007420 brain development
1.60 4.38e-02 GO:0051130 positive regulation of cellular component organization
1.46 4.64e-02 GO:0051338 regulation of transferase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.38 9.16e-13 GO:0044459 plasma membrane part
1.45 1.47e-09 GO:0031226 intrinsic to plasma membrane
1.44 5.19e-09 GO:0005887 integral to plasma membrane
1.53 2.60e-08 GO:0005626 insoluble fraction
1.45 4.02e-08 GO:0000267 cell fraction
1.50 3.68e-07 GO:0005624 membrane fraction
1.18 7.07e-06 GO:0005886 plasma membrane
1.65 1.78e-05 GO:0045202 synapse
1.17 2.18e-05 GO:0071944 cell periphery
1.36 2.61e-04 GO:0044421 extracellular region part
1.56 7.55e-04 GO:0043005 neuron projection
1.09 2.59e-03 GO:0016020 membrane
1.08 4.37e-03 GO:0005737 cytoplasm
1.67 5.26e-03 GO:0016323 basolateral plasma membrane
1.35 5.92e-03 GO:0031982 vesicle
1.33 6.84e-03 GO:0042995 cell projection
1.55 1.92e-02 GO:0044456 synapse part
1.33 2.14e-02 GO:0031410 cytoplasmic vesicle
1.72 2.14e-02 GO:0030424 axon
1.34 2.16e-02 GO:0031988 membrane-bounded vesicle
1.32 2.67e-02 GO:0005615 extracellular space
1.03 3.35e-02 GO:0044464 cell part
1.03 3.49e-02 GO:0005623 cell
1.33 3.77e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.46 4.42e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 2.00e-13 GO:0005488 binding
1.16 9.40e-12 GO:0005515 protein binding
1.55 1.23e-10 GO:0001071 nucleic acid binding transcription factor activity
1.55 1.23e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.63 2.51e-09 GO:0043565 sequence-specific DNA binding
1.36 4.87e-04 GO:0030528 transcription regulator activity
1.43 4.94e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.47 5.37e-04 GO:0004672 protein kinase activity
1.16 6.17e-04 GO:0046872 metal ion binding
1.16 1.03e-03 GO:0043167 ion binding
1.16 1.41e-03 GO:0043169 cation binding
1.69 1.54e-03 GO:0032403 protein complex binding
1.40 1.58e-03 GO:0019899 enzyme binding
2.15 2.13e-03 GO:0005057 receptor signaling protein activity
1.43 2.26e-03 GO:0046983 protein dimerization activity
1.50 2.84e-03 GO:0030695 GTPase regulator activity
1.38 3.69e-03 GO:0016301 kinase activity
2.62 3.95e-03 GO:0003707 steroid hormone receptor activity
1.33 4.27e-03 GO:0005102 receptor binding
1.37 9.25e-03 GO:0042802 identical protein binding
1.46 1.09e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.49 1.10e-02 GO:0042803 protein homodimerization activity
2.47 1.28e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.56 1.44e-02 GO:0016563 transcription activator activity
1.48 1.66e-02 GO:0008289 lipid binding
4.35 1.98e-02 GO:0005251 delayed rectifier potassium channel activity
1.38 2.04e-02 GO:0005509 calcium ion binding
1.47 2.07e-02 GO:0004674 protein serine/threonine kinase activity
1.65 2.28e-02 GO:0046982 protein heterodimerization activity
1.63 3.31e-02 GO:0019900 kinase binding
1.95 3.36e-02 GO:0019838 growth factor binding
1.75 4.65e-02 GO:0005085 guanyl-nucleotide exchange factor activity