Motif ID: TP53.p2

Z-value: 1.714


Transcription factors associated with TP53.p2:

Gene SymbolEntrez IDGene Name
TP53 7157 tumor protein p53

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TP53chr17_-_75907310.511.4e-15Click!


Activity profile for motif TP53.p2.

activity profile for motif TP53.p2


Sorted Z-values histogram for motif TP53.p2

Sorted Z-values for motif TP53.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TP53.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_64455184 39.376 PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455206 37.642 PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455158 36.840 PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455190 36.717 PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455299 35.464 NM_000942
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr6_+_36644236 34.946 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr20_-_32891075 32.064 NM_000687
AHCY
adenosylhomocysteinase
chr1_+_156052330 30.992 LMNA
lamin A/C
chr17_+_76210329 28.562 BIRC5
baculoviral IAP repeat containing 5
chr2_-_74756824 27.604 AUP1
ancient ubiquitous protein 1
chr17_+_76210276 25.226 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chr6_-_138428477 25.028 NM_022121
PERP
PERP, TP53 apoptosis effector
chr12_+_56498324 24.855 PA2G4
proliferation-associated 2G4, 38kDa
chr20_+_35234152 24.576 C20orf24
chromosome 20 open reading frame 24
chr6_-_30712294 24.416 NM_003897
IER3
immediate early response 3
chr4_-_10118358 24.234 WDR1
WD repeat domain 1
chr1_+_224544550 23.621 CNIH4
cornichon homolog 4 (Drosophila)
chr3_+_127771287 23.326 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr12_+_56498347 23.135 PA2G4
proliferation-associated 2G4, 38kDa
chr4_-_10118378 23.040 WDR1
WD repeat domain 1
chr3_+_23851933 23.019 NM_001202476
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr19_-_2456954 22.999 NM_032737
LMNB2
lamin B2
chr1_+_203830732 22.775 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr20_+_35234077 22.545 NM_001199534
NM_018840
NM_199483
C20orf24


chromosome 20 open reading frame 24


chr9_+_116037913 22.489 NM_001244926
NM_004697
PRPF4

PRP4 pre-mRNA processing factor 4 homolog (yeast)

chr20_+_35234210 22.162 C20orf24
chromosome 20 open reading frame 24
chr5_-_175788714 22.116 NM_001079684
NM_001079685
NM_020444
KIAA1191


KIAA1191


chr1_+_224544590 21.696 NM_014184
CNIH4
cornichon homolog 4 (Drosophila)
chr18_+_57567191 21.599 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chrX_+_154114609 21.520 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr3_+_160118346 21.135 NM_005496
SMC4
structural maintenance of chromosomes 4
chr1_+_203830763 21.020 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr3_+_127771126 20.478 NM_013336
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr10_-_135186836 20.454 NM_004092
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr20_-_47804675 19.939 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr22_-_18257221 19.436 BID
BH3 interacting domain death agonist
chr4_+_41937105 19.212 NM_018126
TMEM33
transmembrane protein 33
chr11_+_74660290 18.861 NM_014752
LOC653566
SPCS2
signal peptidase complex subunit 2 homolog pseudogene
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr10_+_120863558 18.706 FAM45A
family with sequence similarity 45, member A
chrX_+_154611748 18.416 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chrX_-_154688260 18.305 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr2_-_47168870 18.227 MCFD2
multiple coagulation factor deficiency 2
chr1_-_156710902 18.082 NM_024540
NM_145729
MRPL24

mitochondrial ribosomal protein L24

chr7_+_101006121 17.838 NM_133457
EMID2
EMI domain containing 2
chrX_-_153285262 17.619 IRAK1
interleukin-1 receptor-associated kinase 1
chr2_-_47168902 17.349 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr1_+_224544597 17.297 CNIH4
cornichon homolog 4 (Drosophila)
chr18_+_34409058 17.217 NM_020776
KIAA1328
KIAA1328
chr16_-_31106049 17.016 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr9_-_138853146 16.788 NM_016172
UBAC1
UBA domain containing 1
chr22_-_18257194 16.771 BID
BH3 interacting domain death agonist
chr12_+_56498414 16.757 PA2G4
proliferation-associated 2G4, 38kDa
chr20_-_47804903 16.605 NM_001037328
NM_004602
NM_017452
NM_017453
NM_017454
STAU1




staufen, RNA binding protein, homolog 1 (Drosophila)




chr11_+_74660317 16.343 SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_+_41444968 16.263 NM_001905
CTPS
CTP synthase
chr5_+_72794273 16.184 BTF3
basic transcription factor 3
chr4_-_10118296 15.922 WDR1
WD repeat domain 1
chr5_+_72794247 15.666 NM_001037637
NM_001207
BTF3

basic transcription factor 3

chr4_-_10118286 15.316


chr20_-_5100443 15.112 NM_182649
PCNA
proliferating cell nuclear antigen
chr11_+_74660321 15.058 SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr10_+_120863610 15.008 NM_207009
FAM45A
family with sequence similarity 45, member A
chr1_+_43148359 14.763 YBX1
Y box binding protein 1
chr3_-_113465101 14.758 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_-_31106125 14.722 NM_024006
NM_206824
VKORC1

vitamin K epoxide reductase complex, subunit 1

chrX_-_109561314 14.470 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr9_-_138853007 14.202 UBAC1
UBA domain containing 1
chr12_+_56498365 14.168 PA2G4
proliferation-associated 2G4, 38kDa
chr9_+_37422645 14.113 NM_012203
GRHPR
glyoxylate reductase/hydroxypyruvate reductase
chr9_-_104160876 14.011 NM_019051
MRPL50
mitochondrial ribosomal protein L50
chr8_-_22926490 13.675 NM_003842
NM_147187
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr20_-_1373702 13.622 FKBP1A-SDCBP2
FKBP1A
FKBP1A-SDCBP2 readthrough (non-protein coding)
FK506 binding protein 1A, 12kDa
chr12_+_56498334 13.536 PA2G4
proliferation-associated 2G4, 38kDa
chr7_-_74867340 13.008 NM_001145064
GTF2IP1
GATSL2
general transcription factor IIi, pseudogene 1
GATS protein-like 2
chr4_-_10118444 12.896 WDR1
WD repeat domain 1
chr7_+_98972351 12.855 ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr4_-_47916498 12.764 NM_152995
NFXL1
nuclear transcription factor, X-box binding-like 1
chr18_+_12947972 12.521 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr10_+_120863626 12.318 FAM45A
FAM45B
family with sequence similarity 45, member A
family with sequence similarity 45, member A pseudogene
chr1_-_10532603 12.261 NM_004401
NM_213566
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr2_-_198364997 11.958 NM_199440
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr1_+_43824598 11.845 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr19_+_17970670 11.785 NM_000980
RPL18A
ribosomal protein L18a
chr5_+_162864571 11.750 NM_004060
NM_199246
CCNG1

cyclin G1

chr7_-_42971730 11.746 PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr22_-_18257160 11.594 BID
BH3 interacting domain death agonist
chr7_+_140396463 11.529 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr1_-_93645903 11.519 TMED5
transmembrane emp24 protein transport domain containing 5
chr1_-_93646245 11.321 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr6_-_101329197 11.308 NM_006828
NM_022091
ASCC3

activating signal cointegrator 1 complex subunit 3

chrX_+_40440229 11.103 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr11_-_47399903 11.090


chr19_+_42364322 11.082 RPS19
ribosomal protein S19
chr19_+_38865424 11.015 PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr12_+_12966249 10.994 NM_016355
NM_201224
DDX47

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47

chrX_+_38663503 10.991 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr18_+_9913954 10.943 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr5_+_135364583 10.907 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr9_+_116037955 10.875 PRPF4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr22_-_18257238 10.842 NM_001196
NM_001244569
NM_001244570
NM_197967
NM_001244567
BID




BH3 interacting domain death agonist




chr7_-_132766834 10.764 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chrX_+_40440261 10.752 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr15_+_40453209 10.749 NM_001211
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_-_10118500 10.680 NM_005112
NM_017491
WDR1

WD repeat domain 1

chr8_-_146017774 10.626 RPL8
ribosomal protein L8
chr15_-_63449479 10.615 NM_015920
RPS27L
ribosomal protein S27-like
chr16_-_31106093 10.600 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr12_+_53895376 10.589 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr2_+_169312793 10.578 NM_203463
CERS6
ceramide synthase 6
chr16_+_447175 10.405 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr9_+_80911990 10.398 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr20_-_33543582 10.354 NM_000178
GSS
glutathione synthetase
chr15_-_90777144 10.248 CIB1
calcium and integrin binding 1 (calmyrin)
chr1_+_223900212 10.241 CAPN2
calpain 2, (m/II) large subunit
chr11_-_47400096 10.086 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr5_-_176831385 9.976 F12
coagulation factor XII (Hageman factor)
chr7_-_132766697 9.960 NM_017812
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr12_+_109535377 9.801 NM_080911
UNG
uracil-DNA glycosylase
chr18_+_9914032 9.764 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr2_-_74756755 9.757 AUP1
ancient ubiquitous protein 1
chr12_+_116997185 9.710 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr20_-_33543548 9.683 GSS
glutathione synthetase
chr19_+_3572903 9.540 NM_006339
HMG20B
high mobility group 20B
chr2_+_198365012 9.507 HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr12_+_53894704 9.488 NM_004178
NM_134323
TARBP2

TAR (HIV-1) RNA binding protein 2

chr1_-_38412725 9.476 NM_005540
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr2_-_24307179 9.458 NM_001206802
TP53I3
tumor protein p53 inducible protein 3
chr3_-_113464991 9.421 NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_+_67880784 9.415 NM_005796
NUTF2
nuclear transport factor 2
chr19_+_3572950 9.412 HMG20B
high mobility group 20B
chr12_-_76424474 9.314 PHLDA1
pleckstrin homology-like domain, family A, member 1
chrX_+_40440145 9.280 NM_005765
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chrX_-_109561298 9.218 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_-_122712019 9.206 NM_019887
NM_138929
DIABLO

diablo, IAP-binding mitochondrial protein

chr15_-_34635306 9.204 NM_018648
NOP10
NOP10 ribonucleoprotein homolog (yeast)
chr12_-_54070108 9.171 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr12_+_53645985 9.128 MFSD5
major facilitator superfamily domain containing 5
chr7_+_100770378 9.099 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr7_+_98972326 8.935 ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr19_+_42364262 8.900 RPS19
ribosomal protein S19
chr1_+_203830723 8.763 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr19_+_3572958 8.724 HMG20B
high mobility group 20B
chr12_+_53645869 8.653 NM_032889
MFSD5
major facilitator superfamily domain containing 5
chr2_+_113403433 8.517 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr3_+_196466724 8.495 NM_002577
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr10_-_95241943 8.488 NM_013451
NM_133337
MYOF

myoferlin

chr20_-_1373744 8.371 NM_000801
NM_001199786
NM_054014
FKBP1A


FK506 binding protein 1A, 12kDa


chr6_+_34204690 8.330 HMGA1
high mobility group AT-hook 1
chr22_-_36925212 8.316 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr8_-_146017716 8.303 NM_033301
RPL8
ribosomal protein L8
chr10_+_88854900 8.280 NM_019054
FAM35A
family with sequence similarity 35, member A
chr11_+_125439373 8.276 EI24
etoposide induced 2.4 mRNA
chr2_+_69969250 8.244 ANXA4
annexin A4
chr3_+_183892569 8.111 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr5_-_179233772 8.081 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr20_-_48732479 8.080 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr20_+_3869485 7.962 NM_024960
PANK2
pantothenate kinase 2
chr1_+_223900226 7.916 CAPN2
calpain 2, (m/II) large subunit
chr11_+_64889802 7.897 MRPL49
mitochondrial ribosomal protein L49
chr3_+_183892647 7.860 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr21_-_44846927 7.833 NM_173354
SIK1
salt-inducible kinase 1
chr5_-_176778683 7.805 NM_006816
LMAN2
lectin, mannose-binding 2
chr7_-_42971779 7.747 NM_002787
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr11_+_125439363 7.718 EI24
etoposide induced 2.4 mRNA
chr7_+_72569025 7.639 GTF2IP1
general transcription factor IIi, pseudogene 1
chr8_-_22926406 7.635 TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr11_+_64889699 7.626 NM_004927
MRPL49
mitochondrial ribosomal protein L49
chr6_-_114292312 7.619 NM_001527
HDAC2
histone deacetylase 2
chr1_-_153508495 7.546 S100A6
S100 calcium binding protein A6
chr12_+_53895065 7.481 TARBP2
TAR (HIV-1) RNA binding protein 2
chrX_+_38663450 7.464 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr10_-_5931800 7.417 NM_001009941
NM_001009943
NM_019046
ANKRD16


ankyrin repeat domain 16


chr7_+_116166346 7.371 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr18_-_34408699 7.316 TPGS2
tubulin polyglutamylase complex subunit 2
chr20_-_61847446 7.300 NM_017798
YTHDF1
YTH domain family, member 1
chr3_+_183892668 7.272 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_156710855 7.201 MRPL24
mitochondrial ribosomal protein L24
chr20_+_3869593 7.095 NM_153638
PANK2
pantothenate kinase 2
chr12_+_53645906 7.060 MFSD5
major facilitator superfamily domain containing 5
chr3_+_183892662 7.017 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr2_-_120980971 6.891 NM_024121
TMEM185B
transmembrane protein 185B
chr1_+_32645322 6.856 NM_175852
TXLNA
taxilin alpha
chrX_+_38663072 6.840 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr12_-_6451156 6.809 NM_001065
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_-_6453362 6.764 ACOT7
acyl-CoA thioesterase 7
chr1_-_54411245 6.707 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr17_-_80407601 6.659 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr15_-_65477441 6.637 NM_006660
CLPX
ClpX caseinolytic peptidase X homolog (E. coli)
chr15_-_65477645 6.615 CLPX
ClpX caseinolytic peptidase X homolog (E. coli)
chr19_-_2051222 6.612 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr11_+_125439294 6.549 NM_001007277
NM_004879
EI24

etoposide induced 2.4 mRNA

chr5_+_141348692 6.538 NM_183401
RNF14
ring finger protein 14
chr2_-_74756838 6.445 AUP1
ancient ubiquitous protein 1
chr2_-_47142880 6.432 MCFD2
multiple coagulation factor deficiency 2
chr3_-_49066858 6.417 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr6_+_24403144 6.387 NM_020662
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr11_+_9685624 6.345 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr1_+_215178884 6.330 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr1_-_153508463 6.264 S100A6
S100 calcium binding protein A6
chr14_-_68141328 6.237 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.43 1.38e-09 GO:0008152 metabolic process
1.47 3.28e-09 GO:0044237 cellular metabolic process
1.22 4.74e-07 GO:0009987 cellular process
1.41 1.13e-06 GO:0044238 primary metabolic process
2.25 1.72e-05 GO:0042981 regulation of apoptosis
2.24 2.32e-05 GO:0043067 regulation of programmed cell death
2.20 4.02e-05 GO:0010941 regulation of cell death
1.68 1.83e-04 GO:0048522 positive regulation of cellular process
1.61 6.04e-04 GO:0048518 positive regulation of biological process
1.43 1.07e-03 GO:0044260 cellular macromolecule metabolic process
1.64 1.28e-03 GO:0044249 cellular biosynthetic process
1.62 1.41e-03 GO:0009058 biosynthetic process
1.38 2.10e-03 GO:0043170 macromolecule metabolic process
1.51 7.20e-03 GO:0019538 protein metabolic process
2.73 1.06e-02 GO:0044271 cellular nitrogen compound biosynthetic process
4.17 1.17e-02 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
2.77 1.24e-02 GO:0006917 induction of apoptosis
1.56 1.27e-02 GO:0044267 cellular protein metabolic process
2.76 1.30e-02 GO:0012502 induction of programmed cell death
1.66 1.88e-02 GO:0044281 small molecule metabolic process
1.46 2.15e-02 GO:0006807 nitrogen compound metabolic process
1.51 2.28e-02 GO:0071841 cellular component organization or biogenesis at cellular level
3.63 3.00e-02 GO:0031400 negative regulation of protein modification process
2.36 3.28e-02 GO:0043065 positive regulation of apoptosis
3.81 3.35e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
2.34 3.69e-02 GO:0043068 positive regulation of programmed cell death
1.42 4.17e-02 GO:0071840 cellular component organization or biogenesis
1.50 4.53e-02 GO:0071842 cellular component organization at cellular level
2.09 4.72e-02 GO:0006915 apoptosis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 7.38e-17 GO:0044444 cytoplasmic part
1.43 1.31e-15 GO:0005737 cytoplasm
1.24 2.60e-10 GO:0044424 intracellular part
2.01 5.62e-10 GO:0005829 cytosol
1.21 7.70e-09 GO:0005622 intracellular
1.45 1.59e-07 GO:0044446 intracellular organelle part
1.44 1.78e-07 GO:0044422 organelle part
1.28 8.09e-07 GO:0043227 membrane-bounded organelle
2.09 1.11e-06 GO:0005739 mitochondrion
1.28 1.26e-06 GO:0043231 intracellular membrane-bounded organelle
1.24 2.84e-06 GO:0043226 organelle
2.53 3.12e-06 GO:0031967 organelle envelope
1.24 3.99e-06 GO:0043229 intracellular organelle
2.49 5.33e-06 GO:0031975 envelope
1.48 3.14e-04 GO:0032991 macromolecular complex
1.64 6.34e-04 GO:0031090 organelle membrane
5.06 1.17e-03 GO:0042470 melanosome
5.06 1.17e-03 GO:0048770 pigment granule
1.59 1.25e-03 GO:0031974 membrane-enclosed lumen
2.48 2.14e-03 GO:0005740 mitochondrial envelope
2.19 2.16e-03 GO:0044429 mitochondrial part
2.66 6.23e-03 GO:0019866 organelle inner membrane
2.41 7.17e-03 GO:0031966 mitochondrial membrane
1.52 1.11e-02 GO:0043233 organelle lumen
1.54 1.19e-02 GO:0044428 nuclear part
1.50 2.68e-02 GO:0070013 intracellular organelle lumen
1.60 3.50e-02 GO:0012505 endomembrane system
1.41 3.91e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.39 3.07e-09 GO:0005515 protein binding
1.14 1.65e-03 GO:0005488 binding
1.29 1.60e-02 GO:0003824 catalytic activity