Motif ID: UAAUGCU

Z-value: 0.922


Mature miRNA associated with seed UAAUGCU:

NamemiRBase Accession
hsa-miR-155 MIMAT0000646



Activity profile for motif UAAUGCU.

activity profile for motif UAAUGCU


Sorted Z-values histogram for motif UAAUGCU

Sorted Z-values for motif UAAUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_69004614 11.735 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr20_+_48807119 11.028 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chrX_-_73834460 9.848 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr4_+_38665587 9.099 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr3_-_141747434 8.609 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr14_+_75745480 8.515 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_7107986 8.451 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr20_-_39317875 8.254 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_202777545 7.991 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr3_-_141868208 7.630 NM_001178138
NM_001178139
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr19_+_39897457 7.541 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr3_-_123339423 7.375 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr12_-_15038724 7.103 NM_000900
NM_001190839
MGP

matrix Gla protein

chr10_+_104535887 7.066 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr3_-_141719188 6.986 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_47439326 6.941 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr7_-_139876718 6.895 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_+_96869156 6.847 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_120514669 6.215 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr2_-_64881040 6.183 NM_014755
SERTAD2
SERTA domain containing 2
chr14_+_103058988 6.124 NM_015156
RCOR1
REST corepressor 1
chr3_-_123603144 6.065 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr11_-_64646053 6.042 NM_006795
EHD1
EH-domain containing 1
chr15_+_96876568 6.006 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr18_-_45457454 5.838 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr18_-_45456925 5.655 NM_005901
SMAD2
SMAD family member 2
chr15_+_96875793 5.651 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_+_96873845 5.590 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_7107799 5.353 NM_001168344
RREB1
ras responsive element binding protein 1
chr8_-_116681103 4.955 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr11_-_27742224 4.881 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr22_+_37309618 4.818 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr11_+_9596233 4.798 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr16_-_8962842 4.794 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr6_+_15246299 4.770 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr16_-_8962247 4.713 NM_001042476
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr10_+_104503724 4.640 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr16_-_10674443 4.598 NM_001424
EMP2
epithelial membrane protein 2
chr19_-_14629160 4.314 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_-_40631846 4.300 NM_001098634
RBM47
RNA binding motif protein 47
chr3_-_107809754 4.271 NM_001777
NM_198793
CD47

CD47 molecule

chr3_+_187871473 4.171 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_1941157 4.168 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr3_-_113465101 4.091 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_+_69455837 4.028 NM_053056
CCND1
cyclin D1
chr1_-_33841142 3.842 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr1_+_226250407 3.791 NM_002107
H3F3A
H3 histone, family 3A
chr6_-_6320897 3.749 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr11_-_27741192 3.690 NM_001143807
BDNF
brain-derived neurotrophic factor
chr12_+_53774422 3.657 NM_003109
SP1
Sp1 transcription factor
chr18_+_67956136 3.622 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr3_+_187943192 3.610 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_-_51717905 3.596 NM_016293
BIN2
bridging integrator 2
chr7_+_101460881 3.542 NM_181552
CUX1
cut-like homeobox 1
chr4_-_40517913 3.539 NM_019027
RBM47
RNA binding motif protein 47
chr1_-_229569839 3.536 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chrX_-_129244652 3.530 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr12_+_53773924 3.359 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chrX_-_129244471 3.337 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr8_-_134115309 3.294 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr11_+_34654010 3.261 NM_001206616
EHF
ets homologous factor
chr9_+_117349993 3.197 NM_004888
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr11_-_46142955 3.194 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr11_+_9595183 3.192 NM_003390
WEE1
WEE1 homolog (S. pombe)
chr1_-_52456292 3.018 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr2_-_174828775 3.005 NM_001017371
SP3
Sp3 transcription factor
chr3_+_30647901 3.002 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr3_+_180630054 2.968 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr11_-_27723061 2.955 NM_170733
BDNF
brain-derived neurotrophic factor
chr19_+_34663311 2.896 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr15_-_34629941 2.844 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr1_-_179198814 2.757 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr17_-_17184589 2.745 NM_003653
COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
chr2_-_174830429 2.734 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr8_-_57123858 2.716 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr15_-_60884615 2.707 NM_134262
RORA
RAR-related orphan receptor A
chr15_-_34610928 2.705 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_33116748 2.701 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr15_+_49715374 2.699 NM_002009
FGF7
fibroblast growth factor 7
chr3_+_120627026 2.681 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr19_+_11071583 2.644 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr22_+_40573879 2.615 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr3_+_187930720 2.614 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr22_-_50218451 2.594 NM_014577
BRD1
bromodomain containing 1
chr11_+_66886735 2.587 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr6_+_135502445 2.587 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr2_-_217560247 2.551 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_+_114522029 2.544 NM_020190
OLFML3
olfactomedin-like 3
chr11_+_47279467 2.528 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr17_-_43394326 2.492 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr21_+_30671736 2.454 NM_206866
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr17_-_17184011 2.449 NM_001199125
COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
chr12_+_104458235 2.419 NM_013320
HCFC2
host cell factor C2
chr15_-_34630203 2.418 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr17_-_48474910 2.410 NM_018509
LRRC59
leucine rich repeat containing 59
chr2_+_208394615 2.409 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr13_+_20532788 2.401 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr19_+_11071792 2.349 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_+_112938799 2.299 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr6_+_143929316 2.286 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr8_+_40010986 2.284 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr13_+_20532906 2.249 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr7_+_129015483 2.238 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr10_+_69644938 2.222 NM_001142498
SIRT1
sirtuin 1
chr8_-_134072404 2.221 NM_006748
SLA
Src-like-adaptor
chr5_-_95297597 2.213 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr11_-_47400096 2.198 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr18_-_12884140 2.162 NM_001207013
NM_002828
NM_080422
NM_080423
PTPN2



protein tyrosine phosphatase, non-receptor type 2



chr2_+_178077421 2.145 NM_194247
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr15_-_61521478 2.130 NM_134261
RORA
RAR-related orphan receptor A
chrX_+_49832214 2.099 NM_000084
CLCN5
chloride channel 5
chr7_+_106809405 2.078 NM_001244262
NM_012257
HBP1

HMG-box transcription factor 1

chr15_-_60919642 2.056 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr10_+_69644341 2.031 NM_012238
SIRT1
sirtuin 1
chr6_+_108881010 2.030 NM_201559
FOXO3
forkhead box O3
chr11_-_27721179 2.003 NM_170734
BDNF
brain-derived neurotrophic factor
chr11_-_65430427 1.961 NM_001145138
NM_001243984
NM_001243985
NM_021975
RELA



v-rel reticuloendotheliosis viral oncogene homolog A (avian)



chr16_-_20911560 1.950 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr5_+_112312392 1.949 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr6_+_118869441 1.941 NM_002667
PLN
phospholamban
chr17_-_40761404 1.926 NM_178126
FAM134C
family with sequence similarity 134, member C
chr1_+_2160133 1.924 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr17_-_56065596 1.914 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr22_+_40440664 1.891 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr2_-_128100673 1.879 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr20_+_51588945 1.872 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr6_+_163835668 1.863 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr8_-_71520620 1.846 NM_014294
TRAM1
translocation associated membrane protein 1
chr21_+_30671217 1.840 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr15_-_34629044 1.817 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr1_+_193091057 1.808 NM_024529
CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr8_-_67525426 1.797 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr4_-_41216455 1.796 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr1_-_78444772 1.778 NM_003902
FUBP1
far upstream element (FUSE) binding protein 1
chr2_+_233925035 1.771 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chrX_+_107069081 1.757 NM_012216
NM_052817
MID2

midline 2

chr9_-_16870719 1.738 NM_017637
BNC2
basonuclin 2
chr14_+_96968698 1.724 NM_001252006
NM_001252007
NM_032632
PAPOLA


poly(A) polymerase alpha


chr14_+_58765209 1.698 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr10_+_86088156 1.692 NM_018999
FAM190B
family with sequence similarity 190, member B
chrX_-_83442906 1.686 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr11_+_119076974 1.664 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr6_-_108145507 1.615 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_-_154842725 1.609 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr1_+_60280462 1.562 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr8_-_21771111 1.562 NM_003974
DOK2
docking protein 2, 56kDa
chr2_+_228336877 1.543 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr10_+_82213892 1.513 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr1_-_108507474 1.513 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr3_-_160283361 1.502 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr3_+_38495778 1.486 NM_001106
ACVR2B
activin A receptor, type IIB
chr5_+_156607847 1.474 NM_005546
ITK
IL2-inducible T-cell kinase
chr4_+_129730772 1.466 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr16_+_67063035 1.441 NM_001755
NM_022845
CBFB

core-binding factor, beta subunit

chr21_-_28217692 1.438 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_-_85780105 1.437 NM_001008660
NM_001206946
NM_007166
PICALM


phosphatidylinositol binding clathrin assembly protein


chr1_-_108231122 1.419 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr11_-_27721975 1.411 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr9_+_112542496 1.399 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr11_-_85780899 1.390 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_+_117824085 1.353 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr4_-_96470350 1.344 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr3_-_190040192 1.331 NM_021101
CLDN1
claudin 1
chr16_-_48644087 1.328 NM_153029
N4BP1
NEDD4 binding protein 1
chr6_+_149639435 1.304 NM_015093
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr5_+_167718485 1.288 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr20_+_32150139 1.275 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr16_+_69599868 1.272 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr11_+_47270433 1.271 NM_001130102
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr11_-_27681195 1.268 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr17_+_4613780 1.265 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chrX_+_129139163 1.258 NM_021946
BCORL1
BCL6 corepressor-like 1
chr2_-_39347562 1.257 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr13_+_112721912 1.239 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr6_+_108882068 1.226 NM_001455
FOXO3
forkhead box O3
chr5_-_148442606 1.217 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr11_-_27743604 1.209 NM_170731
BDNF
brain-derived neurotrophic factor
chr16_-_51185150 1.165 NM_002968
SALL1
sal-like 1 (Drosophila)
chrX_+_64708614 1.140 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr17_+_57642885 1.138 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr12_-_25055228 1.137 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_-_119812973 1.129 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr7_+_73624086 1.128 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr1_-_225840660 1.125 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr8_+_59465727 1.123 NM_001007067
NM_001007068
NM_001007069
NM_001007070
NM_005625
SDCBP




syndecan binding protein (syntenin)




chr5_+_135468522 1.102 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chr9_-_23826062 1.088 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_+_72112417 1.087 NM_002270
TNPO1
transportin 1
chr8_+_61591239 1.087 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr19_-_37019169 1.084 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr10_-_112064689 1.069 NM_005871
SMNDC1
survival motor neuron domain containing 1
chr5_-_55290601 1.062 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr7_-_44924946 1.039 NM_033224
PURB
purine-rich element binding protein B
chr10_+_114709963 1.028 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_-_158731622 1.007 NM_001105
ACVR1
activin A receptor, type I
chr9_-_14314036 1.001 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr20_+_45523247 0.988 NM_005244
NM_172110
EYA2

eyes absent homolog 2 (Drosophila)

chr12_+_70133179 0.987 NM_175623
NM_175625
RAB3IP

RAB3A interacting protein (rabin3)

chr6_+_149068148 0.968 NM_005715
UST
uronyl-2-sulfotransferase
chr12_+_70132562 0.966 NM_022456
NM_175624
RAB3IP

RAB3A interacting protein (rabin3)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.19 7.03e-09 GO:0006351 transcription, DNA-dependent
1.86 5.10e-08 GO:0007275 multicellular organismal development
2.88 2.17e-07 GO:0032774 RNA biosynthetic process
1.78 2.31e-07 GO:0032502 developmental process
1.48 2.47e-07 GO:0050794 regulation of cellular process
2.43 2.88e-07 GO:0009653 anatomical structure morphogenesis
1.69 2.89e-07 GO:0044260 cellular macromolecule metabolic process
2.00 3.90e-07 GO:0010468 regulation of gene expression
2.01 5.52e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.82 6.74e-07 GO:0060255 regulation of macromolecule metabolic process
2.01 9.45e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.78 1.09e-06 GO:0031323 regulation of cellular metabolic process
2.04 1.69e-06 GO:0051252 regulation of RNA metabolic process
3.24 2.30e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.43 2.34e-06 GO:0050789 regulation of biological process
1.71 2.73e-06 GO:0019222 regulation of metabolic process
3.29 2.89e-06 GO:0045893 positive regulation of transcription, DNA-dependent
2.03 4.68e-06 GO:0006355 regulation of transcription, DNA-dependent
1.75 5.41e-06 GO:0080090 regulation of primary metabolic process
1.90 5.44e-06 GO:0009889 regulation of biosynthetic process
1.89 7.39e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.89 7.39e-06 GO:0031326 regulation of cellular biosynthetic process
3.06 1.64e-05 GO:0051254 positive regulation of RNA metabolic process
1.78 1.67e-05 GO:0048856 anatomical structure development
1.56 1.99e-05 GO:0043170 macromolecule metabolic process
3.03 2.08e-05 GO:0010628 positive regulation of gene expression
1.38 2.23e-05 GO:0065007 biological regulation
2.13 2.68e-05 GO:0016070 RNA metabolic process
1.84 2.91e-05 GO:0051171 regulation of nitrogen compound metabolic process
2.07 4.45e-05 GO:0010467 gene expression
2.83 6.65e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
3.38 9.40e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.78 1.02e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.10 1.07e-04 GO:0034645 cellular macromolecule biosynthetic process
1.78 1.14e-04 GO:0048731 system development
1.96 1.44e-04 GO:0030154 cell differentiation
1.50 1.55e-04 GO:0032501 multicellular organismal process
2.08 1.60e-04 GO:0009059 macromolecule biosynthetic process
1.93 1.73e-04 GO:0048869 cellular developmental process
2.70 2.08e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
2.48 2.19e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.01 2.76e-04 GO:0007166 cell surface receptor linked signaling pathway
2.32 3.28e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.87 4.83e-04 GO:0090304 nucleic acid metabolic process
2.22 5.17e-04 GO:0009893 positive regulation of metabolic process
2.25 7.08e-04 GO:0031325 positive regulation of cellular metabolic process
1.86 9.48e-04 GO:0048523 negative regulation of cellular process
1.64 9.60e-04 GO:0007165 signal transduction
2.52 1.04e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.21 1.06e-03 GO:0009987 cellular process
1.80 1.22e-03 GO:0048519 negative regulation of biological process
2.75 1.23e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.73 1.29e-03 GO:0048518 positive regulation of biological process
2.48 1.53e-03 GO:0009891 positive regulation of biosynthetic process
15.98 1.76e-03 GO:0045646 regulation of erythrocyte differentiation
1.77 1.96e-03 GO:0048522 positive regulation of cellular process
7.99 2.23e-03 GO:0007179 transforming growth factor beta receptor signaling pathway
2.77 2.55e-03 GO:0010629 negative regulation of gene expression
21.51 2.64e-03 GO:0032925 regulation of activin receptor signaling pathway
2.89 3.08e-03 GO:0045892 negative regulation of transcription, DNA-dependent
5.86 3.71e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
3.00 4.12e-03 GO:0006325 chromatin organization
2.59 4.24e-03 GO:0009890 negative regulation of biosynthetic process
1.52 4.32e-03 GO:0051716 cellular response to stimulus
2.83 4.42e-03 GO:0051253 negative regulation of RNA metabolic process
2.99 4.45e-03 GO:0072358 cardiovascular system development
2.99 4.45e-03 GO:0072359 circulatory system development
2.57 4.65e-03 GO:0002682 regulation of immune system process
2.68 4.84e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.85 5.94e-03 GO:0048513 organ development
2.32 6.43e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.56 7.75e-03 GO:0045595 regulation of cell differentiation
2.55 8.23e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.06 8.83e-03 GO:0010033 response to organic substance
2.63 1.02e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.17 1.09e-02 GO:0010646 regulation of cell communication
2.60 1.27e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
11.57 1.37e-02 GO:0045669 positive regulation of osteoblast differentiation
2.31 1.39e-02 GO:0009888 tissue development
3.17 1.43e-02 GO:0016568 chromatin modification
2.25 1.66e-02 GO:0050793 regulation of developmental process
4.25 1.69e-02 GO:0002757 immune response-activating signal transduction
1.88 1.78e-02 GO:0023051 regulation of signaling
1.52 1.79e-02 GO:0023052 signaling
2.40 1.83e-02 GO:2000026 regulation of multicellular organismal development
2.88 2.06e-02 GO:0002684 positive regulation of immune system process
4.16 2.17e-02 GO:0002764 immune response-regulating signaling pathway
1.80 2.48e-02 GO:0006464 protein modification process
2.50 2.55e-02 GO:0071310 cellular response to organic substance
2.30 2.70e-02 GO:0048584 positive regulation of response to stimulus
2.60 2.73e-02 GO:0050878 regulation of body fluid levels
1.34 3.10e-02 GO:0044237 cellular metabolic process
2.15 3.24e-02 GO:0009892 negative regulation of metabolic process
2.79 3.28e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.61 3.37e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.20 3.50e-02 GO:0009611 response to wounding
3.34 3.69e-02 GO:0001944 vasculature development
3.68 4.09e-02 GO:0002253 activation of immune response
1.76 4.40e-02 GO:0048583 regulation of response to stimulus
1.68 4.56e-02 GO:0042221 response to chemical stimulus
2.81 4.62e-02 GO:0032583 regulation of gene-specific transcription
2.51 4.88e-02 GO:0042060 wound healing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.63 6.60e-10 GO:0005634 nucleus
2.60 4.84e-09 GO:0005654 nucleoplasm
2.16 7.97e-09 GO:0044428 nuclear part
2.28 1.01e-08 GO:0031981 nuclear lumen
1.95 1.80e-06 GO:0043233 organelle lumen
1.92 3.63e-06 GO:0031974 membrane-enclosed lumen
2.89 4.03e-06 GO:0044451 nucleoplasm part
1.94 4.18e-06 GO:0070013 intracellular organelle lumen
1.21 1.08e-04 GO:0044424 intracellular part
1.18 9.76e-04 GO:0005622 intracellular
1.27 1.03e-03 GO:0043231 intracellular membrane-bounded organelle
1.26 1.12e-03 GO:0043227 membrane-bounded organelle
7.99 1.35e-03 GO:0016605 PML body
1.22 5.72e-03 GO:0043229 intracellular organelle
1.21 6.59e-03 GO:0043226 organelle
3.22 2.71e-02 GO:0005667 transcription factor complex
1.51 3.07e-02 GO:0043234 protein complex
1.45 3.30e-02 GO:0032991 macromolecular complex
3.32 3.49e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.07 1.92e-10 GO:0001071 nucleic acid binding transcription factor activity
3.07 1.92e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 6.98e-08 GO:0005515 protein binding
1.90 7.53e-06 GO:0003677 DNA binding
1.21 8.04e-06 GO:0005488 binding
1.68 2.93e-05 GO:0003676 nucleic acid binding
2.41 4.76e-05 GO:0030528 transcription regulator activity
6.15 4.93e-04 GO:0005057 receptor signaling protein activity
2.61 4.99e-04 GO:0043565 sequence-specific DNA binding
5.75 9.65e-04 GO:0019838 growth factor binding
3.52 1.22e-03 GO:0008134 transcription factor binding
8.70 3.92e-03 GO:0046332 SMAD binding
41.94 6.26e-03 GO:0004897 ciliary neurotrophic factor receptor activity
7.99 6.98e-03 GO:0004702 receptor signaling protein serine/threonine kinase activity
3.09 1.22e-02 GO:0016563 transcription activator activity
33.55 1.54e-02 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
2.67 2.04e-02 GO:0004674 protein serine/threonine kinase activity
2.21 2.22e-02 GO:0019899 enzyme binding
5.67 2.35e-02 GO:0031625 ubiquitin protein ligase binding
15.98 2.45e-02 GO:0070491 repressing transcription factor binding
2.31 3.79e-02 GO:0004672 protein kinase activity