Motif ID: UCCAGUU

Z-value: 1.636


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145 MIMAT0000437



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_86046434 40.484 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr1_-_94703252 39.020 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr7_+_116139619 34.356 NM_001206747
NM_001233
NM_198212
CAV2


caveolin 2


chr3_-_195808958 33.997 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 33.665 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr7_+_116140097 32.625 NM_001206748
CAV2
caveolin 2
chr8_-_12973752 31.267 NM_001164271
DLC1
deleted in liver cancer 1
chr7_+_130131921 29.156 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr18_-_812268 28.271 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr19_+_16178170 28.061 NM_001145160
TPM4
tropomyosin 4
chr19_+_16187047 26.718 NM_003290
TPM4
tropomyosin 4
chr7_+_130131172 26.702 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr2_+_9346876 25.637 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr11_-_102323353 25.339 NM_052932
TMEM123
transmembrane protein 123
chr7_-_131241321 25.146 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr1_-_94374986 24.909 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr7_+_100770378 24.364 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr3_+_180630054 23.206 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr7_+_130126035 22.597 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr19_-_2456954 22.388 NM_032737
LMNB2
lamin B2
chr8_+_98656329 22.275 NM_178812
MTDH
metadherin
chr7_+_872137 22.218 NM_001130965
SUN1
Sad1 and UNC84 domain containing 1
chr5_-_121412805 21.837 NM_001178102
LOX
lysyl oxidase
chr5_-_179229874 21.435 NM_054013
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr8_-_12990731 21.293 NM_006094
DLC1
deleted in liver cancer 1
chr5_-_179233772 21.010 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr17_+_37026111 20.319 NM_006148
LASP1
LIM and SH3 protein 1
chrX_-_99891690 20.127 NM_003270
TSPAN6
tetraspanin 6
chr15_+_67418053 19.927 NM_001145102
SMAD3
SMAD family member 3
chr7_+_5632435 19.572 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr11_+_57529233 19.089 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr10_-_74856656 18.912 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr3_-_134093235 18.773 NM_016201
AMOTL2
angiomotin like 2
chr10_+_5488521 18.408 NM_005863
NET1
neuroepithelial cell transforming 1
chrX_-_108976509 17.767 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr1_-_159895279 17.445 NM_003564
TAGLN2
transgelin 2
chr18_+_3247527 17.288 NM_006471
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_+_94285620 17.267 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr6_+_151646634 16.935 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_67458492 16.790 NM_001145104
SMAD3
SMAD family member 3
chr2_-_37544165 16.722 NM_005813
PRKD3
protein kinase D3
chr14_-_45603668 16.264 NM_002013
FKBP3
FK506 binding protein 3, 25kDa
chr10_+_17686123 16.177 NM_003473
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr3_+_171757413 16.154 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr3_-_15839674 16.138 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr3_+_57994087 16.077 NM_001164317
NM_001164318
NM_001164319
NM_001457
FLNB



filamin B, beta



chr2_-_174828775 15.585 NM_001017371
SP3
Sp3 transcription factor
chr2_-_227663454 15.584 NM_005544
IRS1
insulin receptor substrate 1
chr7_+_94285676 15.563 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr12_+_13043955 15.159 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr1_-_183604885 15.016 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr6_+_151561094 14.876 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_16760147 14.872 NM_014267
C11orf58
chromosome 11 open reading frame 58
chr12_-_54653317 14.833 NM_001127322
CBX5
chromobox homolog 5
chr2_-_106810781 14.208 NM_025076
UXS1
UDP-glucuronate decarboxylase 1
chr12_-_54653369 14.143 NM_001127321
CBX5
chromobox homolog 5
chr18_+_33234532 14.055 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr9_-_14398981 14.023 NM_001190738
NFIB
nuclear factor I/B
chr17_+_33914278 14.019 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr9_-_14314036 13.862 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr11_+_9406123 13.774 NM_006391
IPO7
importin 7
chr17_+_45727274 13.593 NM_002265
KPNB1
karyopherin (importin) beta 1
chr7_-_10979752 13.240 NM_002489
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr17_+_70117154 13.169 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr12_-_76478737 13.020 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr12_-_120687956 12.980 NM_025157
PXN
paxillin
chr20_+_61427804 12.642 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr17_-_46682333 12.635 NM_018952
HOXB6
homeobox B6
chr1_-_115259433 12.619 NM_002524
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr2_+_36583369 12.541 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_-_121414011 12.343 NM_002317
LOX
lysyl oxidase
chr2_-_148779172 12.330 NM_181742
ORC4
origin recognition complex, subunit 4
chr10_+_5454516 12.251 NM_001047160
NET1
neuroepithelial cell transforming 1
chr2_+_121103670 12.158 NM_002193
INHBB
inhibin, beta B
chr8_+_95732101 12.096 NM_181787
DPY19L4
dpy-19-like 4 (C. elegans)
chr17_-_40307015 12.041 NM_001252039
NM_004583
NM_201434
RAB5C


RAB5C, member RAS oncogene family


chr20_-_62601140 12.001 NM_020713
ZNF512B
zinc finger protein 512B
chr2_-_242212244 11.962 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chrX_+_48432740 11.725 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr14_+_67707825 11.681 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr3_-_15798057 11.614 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr5_+_86564727 11.557 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr1_+_166808721 11.551 NM_017542
POGK
pogo transposable element with KRAB domain
chr14_-_35099296 11.429 NM_021249
NM_152233
SNX6

sorting nexin 6

chr1_+_89149836 11.192 NM_006256
PKN2
protein kinase N2
chr3_+_171758289 11.079 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr10_-_118032717 11.020 NM_001145453
GFRA1
GDNF family receptor alpha 1
chr2_-_174830429 10.950 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr9_-_112191105 10.871 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr17_+_72983723 10.854 NM_014603
CDR2L
cerebellar degeneration-related protein 2-like
chr9_-_112213663 10.846 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr15_+_67430358 10.614 NM_001145103
SMAD3
SMAD family member 3
chr5_+_86564044 10.327 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr20_+_19870209 10.248 NM_018993
RIN2
Ras and Rab interactor 2
chr19_-_11308184 9.831 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr9_+_112542496 9.788 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr7_+_28475233 9.684 NM_004904
CREB5
cAMP responsive element binding protein 5
chr4_+_144434555 9.636 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr20_+_19867075 9.615 NM_001242581
RIN2
Ras and Rab interactor 2
chr2_+_102314162 9.562 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr10_-_118032975 9.524 NM_005264
GFRA1
GDNF family receptor alpha 1
chrX_+_100663120 9.521 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr4_+_184020343 9.472 NM_024949
WWC2
WW and C2 domain containing 2
chr19_-_11305186 9.414 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr10_-_118031542 9.357 NM_145793
GFRA1
GDNF family receptor alpha 1
chr1_-_32385258 9.300 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr7_-_6865857 9.275 NM_198097
CCZ1B
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr10_-_931694 9.244 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr1_+_29063443 9.199 NM_001172828
YTHDF2
YTH domain family, member 2
chr5_+_122181159 9.192 NM_014035
SNX24
sorting nexin 24
chr11_+_107879407 9.174 NM_003478
CUL5
cullin 5
chr1_-_155232091 9.168 NM_005698
NM_052837
SCAMP3

secretory carrier membrane protein 3

chrX_-_73834460 9.046 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr11_-_66112537 8.998 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr6_+_7107986 8.969 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr1_+_29063132 8.934 NM_001173128
NM_016258
YTHDF2

YTH domain family, member 2

chr9_+_128510477 8.891 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr15_+_67358194 8.887 NM_005902
SMAD3
SMAD family member 3
chr14_-_75179739 8.861 NM_001039479
KIAA0317
KIAA0317
chr17_-_42275425 8.855 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr1_+_224301790 8.786 NM_001136115
NM_015176
FBXO28

F-box protein 28

chrX_-_10544852 8.733 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr10_-_101945787 8.702 NM_001100626
ERLIN1
ER lipid raft associated 1
chr4_-_40517913 8.685 NM_019027
RBM47
RNA binding motif protein 47
chr12_-_89746244 8.508 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr11_-_6704517 8.501 NM_022061
MRPL17
mitochondrial ribosomal protein L17
chr12_+_52347163 8.482 NM_020327
ACVR1B
activin A receptor, type IB
chr7_+_28725597 8.414 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_-_144385647 8.043 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr4_-_53522756 8.034 NM_001134223
USP46
ubiquitin specific peptidase 46
chr19_-_42759279 7.947 NM_006494
ERF
Ets2 repressor factor
chr4_-_122744978 7.926 NM_001237
CCNA2
cyclin A2
chr12_-_120703549 7.839 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr6_+_20402040 7.828 NM_001949
E2F3
E2F transcription factor 3
chrX_-_10588458 7.827 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_+_86748870 7.749 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr1_-_32403975 7.735 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_-_201828180 7.714 NM_006190
ORC2
origin recognition complex, subunit 2
chr18_-_18691765 7.701 NM_005406
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr10_-_101945686 7.669 NM_006459
ERLIN1
ER lipid raft associated 1
chr15_+_41523401 7.609 NM_007236
CHP
calcium binding protein P22
chr3_+_169684549 7.587 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr4_+_146019155 7.581 NM_001040876
NM_002940
ABCE1

ATP-binding cassette, sub-family E (OABP), member 1

chr20_+_1093905 7.422 NM_178578
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_-_107690526 7.410 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_90024271 7.366 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr2_-_214015053 7.230 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr7_+_129710336 7.223 NM_014997
KLHDC10
kelch domain containing 10
chr14_-_54955714 7.219 NM_004124
GMFB
glia maturation factor, beta
chr11_-_118966175 7.213 NM_002105
H2AFX
H2A histone family, member X
chr5_+_134094460 7.194 NM_014829
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr2_+_204571197 7.193 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr9_-_112260529 7.182 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr14_+_32546445 7.149 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr12_+_78225068 6.976 NM_014903
NAV3
neuron navigator 3
chr18_+_55816546 6.945 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr16_+_67063035 6.881 NM_001755
NM_022845
CBFB

core-binding factor, beta subunit

chr6_+_143999058 6.830 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chrX_-_10645726 6.823 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr12_-_57030083 6.747 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chrX_-_10851808 6.725 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr6_-_83903632 6.699 NM_001199917
PGM3
phosphoglucomutase 3
chr6_+_7107799 6.694 NM_001168344
RREB1
ras responsive element binding protein 1
chr6_+_143929316 6.689 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr17_-_1359410 6.619 NM_005206
NM_016823
CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)

chr1_+_28764660 6.611 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr12_-_125348422 6.608 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr4_-_40631846 6.567 NM_001098634
RBM47
RNA binding motif protein 47
chr2_-_148778262 6.440 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr14_-_20020271 6.434 NM_001145442
POTEG
POTEM
POTE ankyrin domain family, member G
POTE ankyrin domain family, member M
chrX_-_20284708 6.360 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_+_99192696 6.351 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr3_-_148804122 6.304 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr3_-_113465101 6.204 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_-_24586178 6.195 NM_001358
DHX15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr7_-_50800018 6.189 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chr11_+_34073188 6.175 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr18_+_55714457 6.075 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_12947972 5.947 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr6_-_11382501 5.882 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_70485204 5.879 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr16_+_69220940 5.804 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr10_-_133795311 5.790 NM_004052
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr9_+_128509616 5.745 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr1_+_218518675 5.732 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr8_+_30241943 5.712 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr1_+_200708604 5.576 NM_203459
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr7_-_50772997 5.565 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr5_-_77944341 5.557 NM_005779
LHFPL2
lipoma HMGIC fusion partner-like 2
chr1_+_167691156 5.545 NM_001146191
NM_003953
NM_024569
MPZL1


myelin protein zero-like 1


chr1_+_89990396 5.498 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr5_-_133304274 5.471 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr17_+_46985720 5.376 NM_023079
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr18_+_55862577 5.360 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_-_69215699 5.296 NM_001031732
NM_133370
YTHDC1

YTH domain containing 1

chr4_-_53525316 5.291 NM_022832
USP46
ubiquitin specific peptidase 46
chr1_-_38325224 5.265 NM_005955
MTF1
metal-regulatory transcription factor 1
chr17_+_58677489 5.235 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr6_-_150067631 5.193 NM_198887
NUP43
nucleoporin 43kDa
chr2_+_202899309 5.187 NM_003507
FZD7
frizzled family receptor 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.86e-08 GO:0009987 cellular process
1.40 4.91e-07 GO:0065007 biological regulation
1.58 1.50e-05 GO:0044260 cellular macromolecule metabolic process
1.38 2.01e-05 GO:0050789 regulation of biological process
2.00 3.38e-05 GO:0048583 regulation of response to stimulus
1.39 6.83e-05 GO:0050794 regulation of cellular process
2.14 1.02e-04 GO:0009966 regulation of signal transduction
1.41 1.31e-04 GO:0044237 cellular metabolic process
2.03 1.50e-04 GO:0023051 regulation of signaling
1.62 4.68e-04 GO:0016043 cellular component organization
1.39 5.11e-04 GO:0044238 primary metabolic process
2.69 6.17e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.47 6.38e-04 GO:0043170 macromolecule metabolic process
1.55 7.05e-04 GO:0019222 regulation of metabolic process
1.57 2.15e-03 GO:0071840 cellular component organization or biogenesis
2.68 2.47e-03 GO:0042060 wound healing
1.31 6.40e-03 GO:0008152 metabolic process
1.64 8.31e-03 GO:0071842 cellular component organization at cellular level
1.70 9.00e-03 GO:0042221 response to chemical stimulus
1.54 9.29e-03 GO:0060255 regulation of macromolecule metabolic process
2.13 1.47e-02 GO:0032879 regulation of localization
1.51 1.53e-02 GO:0080090 regulation of primary metabolic process
1.65 1.54e-02 GO:0048522 positive regulation of cellular process
1.55 1.73e-02 GO:0034641 cellular nitrogen compound metabolic process
1.53 2.09e-02 GO:0006807 nitrogen compound metabolic process
1.74 2.11e-02 GO:0043412 macromolecule modification
1.49 2.73e-02 GO:0031323 regulation of cellular metabolic process
1.59 2.74e-02 GO:0048518 positive regulation of biological process
1.58 3.08e-02 GO:0071841 cellular component organization or biogenesis at cellular level
2.27 4.06e-02 GO:0051049 regulation of transport
2.54 4.72e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 2.32e-09 GO:0044424 intracellular part
1.25 4.45e-09 GO:0005622 intracellular
1.34 1.09e-06 GO:0005737 cytoplasm
2.11 2.75e-06 GO:0012505 endomembrane system
1.47 4.43e-06 GO:0044446 intracellular organelle part
1.46 6.76e-06 GO:0044422 organelle part
1.30 8.29e-06 GO:0043231 intracellular membrane-bounded organelle
1.30 9.26e-06 GO:0043227 membrane-bounded organelle
1.26 1.77e-05 GO:0043229 intracellular organelle
1.26 2.14e-05 GO:0043226 organelle
6.47 2.54e-04 GO:0030027 lamellipodium
3.79 3.90e-04 GO:0005635 nuclear envelope
1.39 6.91e-04 GO:0005634 nucleus
1.36 7.61e-04 GO:0044444 cytoplasmic part
1.73 8.01e-04 GO:0044428 nuclear part
4.14 9.71e-04 GO:0031252 cell leading edge
1.66 6.63e-03 GO:0031090 organelle membrane
1.61 1.09e-02 GO:0043233 organelle lumen
1.64 1.17e-02 GO:0005829 cytosol
1.69 1.29e-02 GO:0031981 nuclear lumen
2.06 1.56e-02 GO:0042995 cell projection
1.58 1.83e-02 GO:0031974 membrane-enclosed lumen
5.73 1.88e-02 GO:0005643 nuclear pore
1.08 2.22e-02 GO:0044464 cell part
1.08 2.24e-02 GO:0005623 cell
1.57 3.45e-02 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 3.09e-10 GO:0005515 protein binding
1.20 8.95e-06 GO:0005488 binding
2.99 7.44e-03 GO:0003779 actin binding
37.04 9.88e-03 GO:0005010 insulin-like growth factor receptor activity
2.16 1.57e-02 GO:0019899 enzyme binding
29.63 2.43e-02 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity