Motif ID: YY1.p2

Z-value: 7.383


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
YY1chr14_+_1007054320.865.5e-65Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_97274106 119.585 PTDSS1
phosphatidylserine synthase 1
chr20_-_34243118 115.254 RBM12
RNA binding motif protein 12
chr11_+_114310107 108.628 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chrX_-_153285334 105.780 NM_001025242
NM_001025243
NM_001569
IRAK1


interleukin-1 receptor-associated kinase 1


chr16_-_87903028 104.699 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr13_-_37679800 101.687 NM_145203
CSNK1A1L
casein kinase 1, alpha 1-like
chr17_-_4851688 99.717 PFN1
profilin 1
chr1_-_149900143 96.569 NM_005850
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr8_+_26149004 93.504 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_-_23504353 92.505 NM_001144932
NM_002797
NM_001130725
PSMB5


proteasome (prosome, macropain) subunit, beta type, 5


chrX_-_153285262 90.970 IRAK1
interleukin-1 receptor-associated kinase 1
chr2_+_178257371 90.377 NM_003659
AGPS
alkylglycerone phosphate synthase
chr12_+_96252770 89.233 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr17_-_4851797 88.991 NM_005022
PFN1
profilin 1
chr20_-_34330093 88.459 RBM39
RNA binding motif protein 39
chr17_-_4851827 84.799 PFN1
profilin 1
chr11_+_69455837 83.789 NM_053056
CCND1
cyclin D1
chr6_+_36562135 82.457 SRSF3
serine/arginine-rich splicing factor 3
chr2_+_114647699 80.665 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr1_+_203830723 79.412 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_+_27101217 78.836 ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_+_203830732 78.143 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr2_+_114647449 77.400 NM_005721
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr2_+_114647683 77.062 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr12_+_96252705 76.540 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr1_+_203830763 75.706 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr7_+_148892553 74.989 NM_003575
ZNF282
zinc finger protein 282
chr16_-_28857637 74.476 NM_003321
TUFM
Tu translation elongation factor, mitochondrial
chr2_+_178257488 74.410 AGPS
alkylglycerone phosphate synthase
chr14_-_23503924 74.204 PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr5_-_180670732 73.817 GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr8_+_26149043 73.750 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_-_149899623 73.727 SF3B4
splicing factor 3b, subunit 4, 49kDa
chr2_+_114647663 73.520 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr8_+_125486949 73.202 NM_007218
RNF139
ring finger protein 139
chr17_-_1303402 73.133 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr19_+_16178170 72.616 NM_001145160
TPM4
tropomyosin 4
chr12_-_49960221 71.811 NM_001012300
MCRS1
microspherule protein 1
chr19_+_797448 71.562 PTBP1
polypyrimidine tract binding protein 1
chr7_-_26232148 70.190 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_69455938 70.154 CCND1
cyclin D1
chr10_-_15197345 69.902 LOC100192204
peptidylprolyl isomerase A (cyclophilin A) pseudogene
chr19_+_797452 69.839 PTBP1
polypyrimidine tract binding protein 1
chr8_+_26149080 69.311 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr17_+_36908999 69.130 NM_002795
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr8_+_125487193 69.039 RNF139
ring finger protein 139
chr19_-_13044524 68.648 FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr19_-_13044528 68.315 NM_004461
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr3_-_185655648 68.004 TRA2B
transformer 2 beta homolog (Drosophila)
chr1_+_161719540 66.935 NM_007240
DUSP12
dual specificity phosphatase 12
chr14_+_100705432 66.912 YY1
YY1 transcription factor
chr17_-_40169670 66.910 NM_003315
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr6_+_36562139 66.894 SRSF3
serine/arginine-rich splicing factor 3
chr1_-_226595533 66.716 PARP1
poly (ADP-ribose) polymerase 1
chr19_+_797390 66.466 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr9_+_131451847 65.732 SET
SET nuclear oncogene
chr7_-_72936538 65.347 BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr3_+_197677049 64.475 NM_000996
RPL35A
ribosomal protein L35a
chrX_-_118986908 63.678 NM_023010
NM_080632
UPF3B

UPF3 regulator of nonsense transcripts homolog B (yeast)

chr3_-_53290099 63.575 NM_001064
NM_001135055
TKT

transketolase

chr8_+_125487113 63.232 RNF139
ring finger protein 139
chr1_+_202976527 62.084 NM_001079809
NM_138391
TMEM183B
TMEM183A
transmembrane protein 183B
transmembrane protein 183A
chr14_-_54908035 61.658 NM_005776
CNIH
cornichon homolog (Drosophila)
chr12_+_104324157 60.988 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr17_+_26794838 60.497


chr19_-_13044459 60.361 FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr1_+_43148096 60.065 YBX1
Y box binding protein 1
chr12_+_131356640 59.665 RAN
RAN, member RAS oncogene family
chr12_+_104324192 59.521 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr20_-_34329872 59.141 RBM39
RNA binding motif protein 39
chr20_-_34330179 58.964 NM_001242599
NM_001242600
NM_004902
NM_184234
RBM39



RNA binding motif protein 39



chr5_-_137878808 58.891 ETF1
eukaryotic translation termination factor 1
chr12_+_104324214 58.880 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_-_49075987 58.263 NM_017822
KANSL2
KAT8 regulatory NSL complex subunit 2
chr1_-_149814264 58.226 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr14_-_23398605 58.102 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr1_-_167906277 57.968 NM_001143674
NM_015415
BRP44

brain protein 44

chr1_+_202976478 57.462 TMEM183B
transmembrane protein 183B
chr15_-_69113255 56.526 NM_006305
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr18_+_9914202 56.428 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_+_68462985 56.110 CCNB1
cyclin B1
chr11_-_14380030 55.836 NM_001177315
NM_001102669
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr3_+_52740099 55.690 SPCS1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr5_-_180670874 55.567 NM_006098
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_149822627 54.848 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr13_-_26789062 54.782 RNF6
ring finger protein (C3H2C3 type) 6
chr12_-_123011457 54.746 NM_023012
RSRC2
arginine/serine-rich coiled-coil 2
chr10_+_75936546 54.659 ADK
adenosine kinase
chr5_+_68462948 54.625 CCNB1
cyclin B1
chr16_+_2564000 54.467 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr10_-_88281486 54.374 WAPAL
wings apart-like homolog (Drosophila)
chr17_-_56084611 54.302 SRSF1
serine/arginine-rich splicing factor 1
chr16_-_28857587 54.285 TUFM
Tu translation elongation factor, mitochondrial
chr20_-_5107185 54.142 NM_002592
PCNA
proliferating cell nuclear antigen
chr8_+_97274158 54.114 NM_014754
PTDSS1
phosphatidylserine synthase 1
chr17_-_80041166 54.078 FASN
fatty acid synthase
chr12_+_104324186 54.055 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_154192654 53.729 NM_001127320
UBAP2L
ubiquitin associated protein 2-like
chr1_+_32688053 53.513 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr20_-_5100443 53.254 NM_182649
PCNA
proliferating cell nuclear antigen
chr6_-_144416633 52.889 SF3B5
splicing factor 3b, subunit 5, 10kDa
chr11_-_66206260 52.822 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr4_-_83295037 52.749 HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr3_+_179322572 52.690 NM_001199957
NM_001199958
NM_002492
NDUFB5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa


chr5_-_179044835 52.454 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_-_14380591 52.255 NM_012250
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr7_+_99686609 52.160 COPS6
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr11_-_62446544 52.078 UBXN1
UBX domain protein 1
chr10_+_28822387 51.808 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr7_+_2394525 51.602 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr10_+_14880137 51.582 NM_016299
HSPA14
heat shock 70kDa protein 14
chr8_+_97274137 51.493 PTDSS1
phosphatidylserine synthase 1
chr4_-_83294624 51.482 HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr18_+_9914250 51.117 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_+_68462836 51.018 NM_031966
CCNB1
cyclin B1
chr20_-_49547451 50.845 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr3_-_12705329 50.647 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr5_-_137878915 50.575 NM_004730
ETF1
eukaryotic translation termination factor 1
chr1_+_202976513 50.117 TMEM183A
transmembrane protein 183A
chr10_+_79793517 49.665 NM_001026
NM_001142282
NM_001142283
NM_001142284
NM_001142285
NM_033022
RPS24





ribosomal protein S24





chr7_+_99686604 49.599 COPS6
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr17_-_79478956 49.374 ACTG1
actin, gamma 1
chr17_-_42275425 49.324 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr5_+_65440662 49.103 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr7_+_73097897 49.077 NM_001202560
NM_017528
WBSCR22

Williams Beuren syndrome chromosome region 22

chr14_-_95599794 49.054 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr6_+_36562089 49.016 NM_003017
SRSF3
serine/arginine-rich splicing factor 3
chr1_+_43148048 48.935 NM_004559
YBX1
Y box binding protein 1
chr17_-_61904262 48.828 FTSJ3
FtsJ homolog 3 (E. coli)
chr1_+_32688013 48.655 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr10_+_79793618 48.332 RPS24
ribosomal protein S24
chr4_-_83294806 48.303 HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr7_+_23530136 48.279 RPS2P32
ribosomal protein S2 pseudogene 32
chr20_-_34330177 47.856 RBM39
RNA binding motif protein 39
chr7_+_73097930 47.651 WBSCR22
Williams Beuren syndrome chromosome region 22
chr16_+_2817654 47.503 SRRM2
serine/arginine repetitive matrix 2
chr7_+_2394546 47.363 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr17_+_49243770 47.190 NM_001018139
NME2
non-metastatic cells 2, protein (NM23B) expressed in
chr2_+_242255365 47.080 SEPT2
septin 2
chr2_+_216986817 46.906 XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr12_-_123380608 46.675


chr11_-_64545864 46.636 SF1
splicing factor 1
chr19_+_16187047 46.499 NM_003290
TPM4
tropomyosin 4
chr4_-_120987890 46.413 NM_002358
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr17_-_61904449 46.336 FTSJ3
FtsJ homolog 3 (E. coli)
chr1_-_33282844 46.197 YARS
tyrosyl-tRNA synthetase
chr20_-_33872289 45.977 EIF6
eukaryotic translation initiation factor 6
chr1_+_32687970 45.832 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr10_+_75936524 45.698 ADK
adenosine kinase
chr7_+_2394428 45.687 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr8_-_54934851 45.662 TCEA1
transcription elongation factor A (SII), 1
chr7_-_87849341 45.582 SRI
sorcin
chr1_+_32688010 45.424 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr22_+_21922020 45.404 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr2_-_62115714 45.355 CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr20_-_45985411 44.881 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr1_+_165796652 44.615 NM_012474
UCK2
uridine-cytidine kinase 2
chr11_+_75110552 44.548 NM_001005
RPS3
ribosomal protein S3
chr1_-_25291474 44.539 NM_001031680
RUNX3
runt-related transcription factor 3
chr6_-_144416753 44.490 NM_031287
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr22_+_21922026 44.481 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr5_+_10250410 44.432 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr1_+_43148098 44.364 YBX1
Y box binding protein 1
chr2_+_27851900 44.270 GPN1
GPN-loop GTPase 1
chr11_+_105948291 44.217 NM_015423
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr20_-_60718440 44.083 NM_002792
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr1_-_153643456 43.983 ILF2
interleukin enhancer binding factor 2, 45kDa
chr12_+_7080077 43.982 EMG1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr1_+_43148142 43.874 YBX1
Y box binding protein 1
chr20_-_33872505 43.717 NM_181468
EIF6
eukaryotic translation initiation factor 6
chr3_-_150264134 43.630 SERP1
stress-associated endoplasmic reticulum protein 1
chr5_-_172083569 43.441


chr20_-_32699915 43.335 EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr14_+_102276279 43.273 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_-_174828775 43.114 NM_001017371
SP3
Sp3 transcription factor
chr1_+_43162386 43.094 YBX1
Y box binding protein 1
chr12_+_7079943 43.061 NM_006331
EMG1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr1_+_113162074 43.041 NM_006135
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr20_-_3765747 43.002 CENPB
centromere protein B, 80kDa
chr22_+_21922004 42.869 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr17_+_49244082 42.802 NM_001018138
NME2
non-metastatic cells 2, protein (NM23B) expressed in
chr11_-_14665162 42.715 NM_148976
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr1_-_153643474 42.684 NM_004515
ILF2
interleukin enhancer binding factor 2, 45kDa
chr17_-_79478236 42.613 ACTG1
actin, gamma 1
chr17_-_40169400 42.609 DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_-_123303836 42.574 NM_198402
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr22_-_42611310 42.525 NM_005650
NM_181492
TCF20

transcription factor 20 (AR1)

chr8_-_67974548 42.512 NM_006837
COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr5_+_70944968 42.425 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_+_200819928 42.248 NM_024520
C2orf47
chromosome 2 open reading frame 47
chr14_+_78174424 42.196 NM_031210
SLIRP
SRA stem-loop interacting RNA binding protein
chr10_+_28822428 42.178 WAC
WW domain containing adaptor with coiled-coil
chr1_-_222885653 41.936 NM_022831
AIDA
axin interactor, dorsalization associated
chr2_+_27851862 41.912 NM_007266
GPN1
GPN-loop GTPase 1
chr1_-_33283632 41.877 NM_003680
YARS
tyrosyl-tRNA synthetase
chr5_+_10250377 41.858 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr17_-_40169447 41.853 DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr8_+_98656329 41.848 NM_178812
MTDH
metadherin
chr16_+_56817367 41.846 NM_001242796
NUP93
nucleoporin 93kDa
chr14_+_78174438 41.820 SLIRP
SRA stem-loop interacting RNA binding protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.46 1.44e-102 GO:0044237 cellular metabolic process
1.23 5.07e-90 GO:0009987 cellular process
1.55 7.02e-86 GO:0044260 cellular macromolecule metabolic process
1.37 1.24e-82 GO:0008152 metabolic process
1.38 1.52e-72 GO:0044238 primary metabolic process
1.46 7.74e-72 GO:0043170 macromolecule metabolic process
1.68 4.04e-69 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.62e-64 GO:0006807 nitrogen compound metabolic process
1.74 1.16e-63 GO:0090304 nucleic acid metabolic process
1.59 1.51e-63 GO:0034641 cellular nitrogen compound metabolic process
1.82 4.04e-63 GO:0010467 gene expression
1.82 9.02e-58 GO:0016070 RNA metabolic process
1.60 6.61e-46 GO:0044249 cellular biosynthetic process
1.56 1.39e-42 GO:0009058 biosynthetic process
1.55 8.11e-41 GO:0044267 cellular protein metabolic process
2.19 9.86e-41 GO:0006396 RNA processing
2.28 1.05e-38 GO:0016071 mRNA metabolic process
1.68 2.75e-38 GO:0009059 macromolecule biosynthetic process
1.68 6.39e-38 GO:0034645 cellular macromolecule biosynthetic process
1.50 3.34e-37 GO:0071841 cellular component organization or biogenesis at cellular level
1.42 3.56e-35 GO:0071840 cellular component organization or biogenesis
2.63 4.81e-35 GO:0006412 translation
2.24 3.53e-33 GO:0034621 cellular macromolecular complex subunit organization
1.48 3.98e-32 GO:0071842 cellular component organization at cellular level
2.56 9.95e-32 GO:0008380 RNA splicing
1.41 1.01e-31 GO:0016043 cellular component organization
2.33 1.05e-29 GO:0006397 mRNA processing
1.88 1.53e-29 GO:0043933 macromolecular complex subunit organization
2.27 7.45e-29 GO:0016032 viral reproduction
1.41 3.89e-28 GO:0019538 protein metabolic process
1.58 4.04e-27 GO:0006996 organelle organization
2.75 2.38e-26 GO:0000375 RNA splicing, via transesterification reactions
3.63 3.11e-25 GO:0006415 translational termination
2.94 3.44e-25 GO:0022415 viral reproductive process
2.73 7.66e-25 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.73 7.66e-25 GO:0000398 nuclear mRNA splicing, via spliceosome
3.59 1.53e-23 GO:0019080 viral genome expression
3.59 1.53e-23 GO:0019083 viral transcription
3.38 1.79e-23 GO:0006414 translational elongation
3.00 8.90e-23 GO:0019058 viral infectious cycle
3.22 1.75e-22 GO:0032984 macromolecular complex disassembly
3.22 1.75e-22 GO:0034623 cellular macromolecular complex disassembly
1.79 1.86e-22 GO:0046907 intracellular transport
3.34 7.09e-22 GO:0043241 protein complex disassembly
3.34 7.09e-22 GO:0043624 cellular protein complex disassembly
1.95 6.55e-21 GO:0044265 cellular macromolecule catabolic process
1.91 7.11e-21 GO:0000278 mitotic cell cycle
1.61 1.89e-20 GO:0044248 cellular catabolic process
2.59 5.62e-20 GO:0022411 cellular component disassembly
2.59 5.62e-20 GO:0071845 cellular component disassembly at cellular level
1.86 5.64e-20 GO:0009057 macromolecule catabolic process
1.60 6.33e-20 GO:0044085 cellular component biogenesis
1.87 1.64e-19 GO:0071822 protein complex subunit organization
2.20 8.61e-19 GO:0051325 interphase
1.60 9.91e-19 GO:0051649 establishment of localization in cell
1.56 1.55e-18 GO:0051641 cellular localization
1.64 1.76e-18 GO:0032774 RNA biosynthetic process
2.17 1.45e-17 GO:0051329 interphase of mitotic cell cycle
1.61 1.97e-17 GO:0007049 cell cycle
2.06 2.46e-17 GO:0044419 interspecies interaction between organisms
1.50 3.35e-17 GO:0009056 catabolic process
2.44 4.72e-17 GO:0022613 ribonucleoprotein complex biogenesis
1.75 5.28e-17 GO:0022403 cell cycle phase
2.85 8.68e-17 GO:0031018 endocrine pancreas development
1.65 3.77e-16 GO:0015031 protein transport
2.37 3.90e-16 GO:0071843 cellular component biogenesis at cellular level
1.51 6.08e-16 GO:0033036 macromolecule localization
1.66 1.26e-15 GO:0022402 cell cycle process
1.63 3.01e-15 GO:0045184 establishment of protein localization
2.05 4.80e-15 GO:0043632 modification-dependent macromolecule catabolic process
2.03 2.09e-14 GO:0019941 modification-dependent protein catabolic process
2.57 2.40e-14 GO:0031016 pancreas development
2.67 2.44e-14 GO:0045333 cellular respiration
1.54 2.88e-14 GO:0008104 protein localization
2.66 6.62e-14 GO:0042254 ribosome biogenesis
1.98 8.85e-14 GO:0044257 cellular protein catabolic process
1.99 1.02e-13 GO:0051603 proteolysis involved in cellular protein catabolic process
1.67 1.11e-13 GO:0065003 macromolecular complex assembly
2.59 1.76e-13 GO:0022900 electron transport chain
2.52 1.86e-13 GO:0000082 G1/S transition of mitotic cell cycle
2.01 1.95e-13 GO:0006511 ubiquitin-dependent protein catabolic process
1.94 1.95e-13 GO:0034622 cellular macromolecular complex assembly
2.89 2.19e-13 GO:0022904 respiratory electron transport chain
1.90 2.39e-13 GO:0006091 generation of precursor metabolites and energy
2.42 3.24e-13 GO:0010498 proteasomal protein catabolic process
2.42 3.24e-13 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.95 3.93e-13 GO:0010564 regulation of cell cycle process
2.22 4.04e-13 GO:0000075 cell cycle checkpoint
1.88 8.95e-13 GO:0006886 intracellular protein transport
1.53 1.10e-12 GO:0032268 regulation of cellular protein metabolic process
2.67 1.25e-12 GO:0051320 S phase
1.59 1.31e-12 GO:0033554 cellular response to stress
1.91 1.37e-12 GO:0030163 protein catabolic process
1.69 1.83e-12 GO:0051276 chromosome organization
1.50 2.44e-12 GO:0051246 regulation of protein metabolic process
2.15 2.91e-12 GO:0071156 regulation of cell cycle arrest
1.34 3.14e-12 GO:0048523 negative regulation of cellular process
1.29 5.62e-12 GO:0048518 positive regulation of biological process
1.67 5.80e-12 GO:0051726 regulation of cell cycle
1.50 7.64e-12 GO:0022607 cellular component assembly
2.63 9.07e-12 GO:0000084 S phase of mitotic cell cycle
2.00 2.90e-11 GO:0015980 energy derivation by oxidation of organic compounds
1.31 3.10e-11 GO:0048519 negative regulation of biological process
2.48 3.44e-11 GO:0007093 mitotic cell cycle checkpoint
3.06 3.62e-11 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.30 3.64e-11 GO:0048522 positive regulation of cellular process
3.00 5.87e-11 GO:0051352 negative regulation of ligase activity
3.00 5.87e-11 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.71 6.93e-11 GO:0070727 cellular macromolecule localization
1.45 8.35e-11 GO:0031325 positive regulation of cellular metabolic process
2.75 8.39e-11 GO:0006364 rRNA processing
1.99 8.71e-11 GO:0007346 regulation of mitotic cell cycle
2.87 9.33e-11 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.58 9.61e-11 GO:0071844 cellular component assembly at cellular level
1.45 1.68e-10 GO:0010604 positive regulation of macromolecule metabolic process
1.70 1.70e-10 GO:0034613 cellular protein localization
2.21 1.78e-10 GO:0035270 endocrine system development
2.55 1.97e-10 GO:0031398 positive regulation of protein ubiquitination
2.73 2.34e-10 GO:0031397 negative regulation of protein ubiquitination
2.79 2.58e-10 GO:0051351 positive regulation of ligase activity
2.02 2.94e-10 GO:0032269 negative regulation of cellular protein metabolic process
2.80 3.73e-10 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.42 4.44e-10 GO:0009893 positive regulation of metabolic process
1.68 5.63e-10 GO:0006974 response to DNA damage stimulus
2.89 7.89e-10 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.50 9.44e-10 GO:0010605 negative regulation of macromolecule metabolic process
2.64 1.49e-09 GO:0051438 regulation of ubiquitin-protein ligase activity
2.78 1.53e-09 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.61 1.81e-09 GO:0016072 rRNA metabolic process
2.28 1.90e-09 GO:0031396 regulation of protein ubiquitination
1.96 2.61e-09 GO:0051248 negative regulation of protein metabolic process
1.70 2.91e-09 GO:0006325 chromatin organization
2.75 2.96e-09 GO:0000216 M/G1 transition of mitotic cell cycle
3.50 3.03e-09 GO:0006413 translational initiation
2.58 3.21e-09 GO:0051340 regulation of ligase activity
1.45 3.22e-09 GO:0042981 regulation of apoptosis
1.92 3.23e-09 GO:0034660 ncRNA metabolic process
1.74 5.28e-09 GO:0051247 positive regulation of protein metabolic process
1.12 8.28e-09 GO:0065007 biological regulation
1.44 9.06e-09 GO:0010941 regulation of cell death
1.44 9.80e-09 GO:0043067 regulation of programmed cell death
1.46 1.02e-08 GO:0009892 negative regulation of metabolic process
2.07 1.14e-08 GO:0034470 ncRNA processing
1.13 1.25e-08 GO:0050789 regulation of biological process
2.17 1.50e-08 GO:0031400 negative regulation of protein modification process
2.42 1.51e-08 GO:0051028 mRNA transport
1.59 1.99e-08 GO:0006259 DNA metabolic process
1.13 2.03e-08 GO:0050794 regulation of cellular process
2.33 2.96e-08 GO:0050657 nucleic acid transport
2.33 2.96e-08 GO:0050658 RNA transport
2.33 2.96e-08 GO:0051236 establishment of RNA localization
1.46 4.22e-08 GO:0031324 negative regulation of cellular metabolic process
1.22 4.50e-08 GO:0060255 regulation of macromolecule metabolic process
2.29 4.81e-08 GO:0006403 RNA localization
1.83 5.28e-08 GO:0006366 transcription from RNA polymerase II promoter
1.47 6.31e-08 GO:0008219 cell death
1.51 1.11e-07 GO:0012501 programmed cell death
1.46 1.12e-07 GO:0016265 death
1.71 1.42e-07 GO:0032270 positive regulation of cellular protein metabolic process
1.20 1.44e-07 GO:0031323 regulation of cellular metabolic process
1.30 1.45e-07 GO:0006464 protein modification process
1.84 1.61e-07 GO:0010608 posttranscriptional regulation of gene expression
1.29 1.79e-07 GO:0043412 macromolecule modification
2.77 2.22e-07 GO:0071158 positive regulation of cell cycle arrest
1.45 4.38e-07 GO:0006351 transcription, DNA-dependent
1.50 4.46e-07 GO:0006915 apoptosis
2.27 5.71e-07 GO:0031570 DNA integrity checkpoint
1.20 6.47e-07 GO:0051179 localization
2.90 6.93e-07 GO:0006521 regulation of cellular amino acid metabolic process
1.48 7.50e-07 GO:0016192 vesicle-mediated transport
1.29 8.28e-07 GO:0044281 small molecule metabolic process
2.75 9.08e-07 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.75 9.08e-07 GO:0072395 signal transduction involved in cell cycle checkpoint
2.75 9.08e-07 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.75 9.08e-07 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.75 9.08e-07 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.75 9.08e-07 GO:0072422 signal transduction involved in DNA damage checkpoint
2.75 9.08e-07 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.75 9.08e-07 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.18 9.40e-07 GO:0019222 regulation of metabolic process
3.07 1.22e-06 GO:0042773 ATP synthesis coupled electron transport
3.07 1.22e-06 GO:0042775 mitochondrial ATP synthesis coupled electron transport
2.29 1.26e-06 GO:0000077 DNA damage checkpoint
1.19 1.54e-06 GO:0080090 regulation of primary metabolic process
2.51 1.60e-06 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.51 1.60e-06 GO:0071779 G1/S transition checkpoint
2.11 1.77e-06 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.21 1.94e-06 GO:0051234 establishment of localization
1.68 2.27e-06 GO:0016568 chromatin modification
2.60 2.61e-06 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.74 2.98e-06 GO:0000087 M phase of mitotic cell cycle
2.44 3.00e-06 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.01 3.72e-06 GO:0006417 regulation of translation
3.24 3.90e-06 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
1.21 4.46e-06 GO:0006810 transport
1.72 7.43e-06 GO:0048610 cellular process involved in reproduction
1.72 8.32e-06 GO:0048285 organelle fission
2.08 8.36e-06 GO:0048193 Golgi vesicle transport
2.85 8.47e-06 GO:0006119 oxidative phosphorylation
1.72 1.17e-05 GO:0000280 nuclear division
1.72 1.17e-05 GO:0007067 mitosis
1.55 1.52e-05 GO:0070271 protein complex biogenesis
1.55 1.72e-05 GO:0006461 protein complex assembly
1.70 2.01e-05 GO:0031401 positive regulation of protein modification process
2.18 2.26e-05 GO:0042770 signal transduction in response to DNA damage
1.42 2.48e-05 GO:0031399 regulation of protein modification process
2.18 3.38e-05 GO:0090068 positive regulation of cell cycle process
1.22 3.75e-05 GO:0006950 response to stress
1.38 4.83e-05 GO:0055114 oxidation-reduction process
1.65 4.86e-05 GO:0009259 ribonucleotide metabolic process
1.50 5.00e-05 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.57 5.10e-05 GO:0072521 purine-containing compound metabolic process
2.28 7.47e-05 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.63 8.45e-05 GO:0006281 DNA repair
1.87 9.46e-05 GO:0051169 nuclear transport
2.30 1.09e-04 GO:0022618 ribonucleoprotein complex assembly
2.48 1.17e-04 GO:0033238 regulation of cellular amine metabolic process
1.86 1.37e-04 GO:0006913 nucleocytoplasmic transport
1.81 1.69e-04 GO:0006457 protein folding
1.63 1.95e-04 GO:0009150 purine ribonucleotide metabolic process
1.89 2.14e-04 GO:0043623 cellular protein complex assembly
1.50 2.19e-04 GO:0044283 small molecule biosynthetic process
2.09 2.27e-04 GO:0000086 G2/M transition of mitotic cell cycle
2.30 2.48e-04 GO:0000956 nuclear-transcribed mRNA catabolic process
2.22 2.61e-04 GO:0071826 ribonucleoprotein complex subunit organization
2.44 2.93e-04 GO:0031124 mRNA 3'-end processing
1.77 4.56e-04 GO:0006605 protein targeting
2.22 5.90e-04 GO:0051168 nuclear export
2.05 6.81e-04 GO:0006401 RNA catabolic process
2.19 8.83e-04 GO:0006402 mRNA catabolic process
2.63 9.85e-04 GO:0006458 'de novo' protein folding
1.80 1.06e-03 GO:0016569 covalent chromatin modification
2.41 1.09e-03 GO:0070925 organelle assembly
1.80 1.17e-03 GO:0016570 histone modification
1.78 1.22e-03 GO:0006260 DNA replication
1.55 1.66e-03 GO:0051301 cell division
1.50 1.86e-03 GO:0000279 M phase
1.46 2.11e-03 GO:0006753 nucleoside phosphate metabolic process
1.46 2.11e-03 GO:0009117 nucleotide metabolic process
1.14 2.18e-03 GO:0051716 cellular response to stimulus
1.56 2.56e-03 GO:0070647 protein modification by small protein conjugation or removal
1.48 3.09e-03 GO:0016044 cellular membrane organization
1.33 3.18e-03 GO:0051704 multi-organism process
1.44 3.86e-03 GO:0044092 negative regulation of molecular function
1.47 4.13e-03 GO:0061024 membrane organization
1.51 4.27e-03 GO:0006163 purine nucleotide metabolic process
2.18 4.49e-03 GO:0031123 RNA 3'-end processing
1.34 5.19e-03 GO:0051128 regulation of cellular component organization
2.62 5.87e-03 GO:0051084 'de novo' posttranslational protein folding
2.10 6.22e-03 GO:0051656 establishment of organelle localization
1.66 7.38e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.52 7.60e-03 GO:0006917 induction of apoptosis
1.57 8.16e-03 GO:0009144 purine nucleoside triphosphate metabolic process
1.37 8.21e-03 GO:0046483 heterocycle metabolic process
1.30 8.39e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.52 8.92e-03 GO:0012502 induction of programmed cell death
2.14 9.91e-03 GO:0006353 transcription termination, DNA-dependent
1.70 9.94e-03 GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process
1.70 9.94e-03 GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
2.55 1.03e-02 GO:0006369 termination of RNA polymerase II transcription
1.82 1.11e-02 GO:0072522 purine-containing compound biosynthetic process
1.27 1.14e-02 GO:0050790 regulation of catalytic activity
2.89 1.14e-02 GO:0009161 ribonucleoside monophosphate metabolic process
1.95 1.18e-02 GO:0009260 ribonucleotide biosynthetic process
1.55 1.74e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.32 1.77e-02 GO:0006508 proteolysis
1.71 1.97e-02 GO:0043687 post-translational protein modification
1.80 2.04e-02 GO:0006333 chromatin assembly or disassembly
1.54 2.06e-02 GO:0009199 ribonucleoside triphosphate metabolic process
2.38 2.10e-02 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
2.98 2.34e-02 GO:0006900 membrane budding
1.92 2.34e-02 GO:0034728 nucleosome organization
1.31 2.34e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.45 2.38e-02 GO:0043086 negative regulation of catalytic activity
1.55 2.39e-02 GO:0032446 protein modification by small protein conjugation
1.87 2.40e-02 GO:0071824 protein-DNA complex subunit organization
1.53 2.65e-02 GO:0009141 nucleoside triphosphate metabolic process
1.40 3.54e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
3.88 3.79e-02 GO:0042273 ribosomal large subunit biogenesis
1.32 3.92e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 4.19e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.46 4.26e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.36 4.32e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.35 4.81e-02 GO:0005975 carbohydrate metabolic process
2.87 4.86e-02 GO:0009156 ribonucleoside monophosphate biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 8.93e-128 GO:0044424 intracellular part
1.24 5.29e-118 GO:0005622 intracellular
1.35 3.83e-107 GO:0005737 cytoplasm
1.48 1.36e-96 GO:0044446 intracellular organelle part
1.48 2.75e-96 GO:0044422 organelle part
1.27 6.69e-92 GO:0043226 organelle
1.27 2.74e-91 GO:0043229 intracellular organelle
1.30 5.67e-85 GO:0043227 membrane-bounded organelle
1.30 5.93e-84 GO:0043231 intracellular membrane-bounded organelle
1.61 6.51e-81 GO:0032991 macromolecular complex
1.41 1.02e-78 GO:0044444 cytoplasmic part
1.76 2.03e-68 GO:0044428 nuclear part
1.69 2.17e-61 GO:0031974 membrane-enclosed lumen
1.68 5.70e-59 GO:0043233 organelle lumen
1.69 9.25e-59 GO:0070013 intracellular organelle lumen
1.70 2.39e-55 GO:0005829 cytosol
1.75 1.70e-54 GO:0031981 nuclear lumen
2.48 5.28e-52 GO:0030529 ribonucleoprotein complex
1.34 1.04e-48 GO:0005634 nucleus
1.47 4.65e-39 GO:0043234 protein complex
1.75 5.50e-38 GO:0005654 nucleoplasm
1.47 7.01e-36 GO:0043228 non-membrane-bounded organelle
1.47 7.01e-36 GO:0043232 intracellular non-membrane-bounded organelle
1.07 8.32e-30 GO:0044464 cell part
1.07 9.45e-30 GO:0005623 cell
1.81 2.04e-22 GO:0031967 organelle envelope
1.56 2.25e-21 GO:0005739 mitochondrion
1.78 4.26e-21 GO:0031975 envelope
2.59 6.06e-21 GO:0005840 ribosome
2.85 1.59e-20 GO:0005681 spliceosomal complex
1.90 2.32e-19 GO:0005730 nucleolus
1.39 1.80e-17 GO:0031090 organelle membrane
3.34 2.33e-17 GO:0022626 cytosolic ribosome
3.13 2.48e-15 GO:0071013 catalytic step 2 spliceosome
1.69 2.78e-15 GO:0044429 mitochondrial part
2.68 5.77e-15 GO:0044455 mitochondrial membrane part
1.73 3.64e-14 GO:0005694 chromosome
1.95 4.29e-14 GO:0019866 organelle inner membrane
2.42 7.81e-14 GO:0044445 cytosolic part
1.63 8.96e-14 GO:0044451 nucleoplasm part
1.76 1.95e-12 GO:0005740 mitochondrial envelope
1.74 7.96e-12 GO:0044427 chromosomal part
1.75 1.56e-11 GO:0031966 mitochondrial membrane
1.89 3.09e-11 GO:0005743 mitochondrial inner membrane
3.06 1.04e-10 GO:0005746 mitochondrial respiratory chain
2.97 1.20e-10 GO:0070469 respiratory chain
3.65 1.65e-10 GO:0022625 cytosolic large ribosomal subunit
2.96 5.05e-10 GO:0000502 proteasome complex
1.35 1.20e-09 GO:0012505 endomembrane system
2.99 1.75e-08 GO:0015935 small ribosomal subunit
1.88 2.19e-08 GO:0005635 nuclear envelope
1.92 2.53e-08 GO:0016604 nuclear body
2.75 1.46e-07 GO:0015934 large ribosomal subunit
3.23 1.47e-07 GO:0005747 mitochondrial respiratory chain complex I
3.23 1.47e-07 GO:0030964 NADH dehydrogenase complex
3.23 1.47e-07 GO:0045271 respiratory chain complex I
3.29 8.06e-07 GO:0022627 cytosolic small ribosomal subunit
1.80 1.27e-06 GO:0000785 chromatin
4.14 1.35e-06 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.90 2.59e-06 GO:0005819 spindle
2.20 2.79e-05 GO:0016585 chromatin remodeling complex
2.36 5.48e-05 GO:0005643 nuclear pore
4.30 6.83e-05 GO:0005852 eukaryotic translation initiation factor 3 complex
1.31 6.92e-05 GO:0000267 cell fraction
1.90 9.39e-05 GO:0000775 chromosome, centromeric region
1.73 9.59e-05 GO:0000228 nuclear chromosome
1.88 1.82e-04 GO:0031965 nuclear membrane
1.39 1.90e-04 GO:0015630 microtubule cytoskeleton
1.64 2.55e-04 GO:0005759 mitochondrial matrix
1.30 2.81e-04 GO:0005783 endoplasmic reticulum
2.12 2.99e-04 GO:0000776 kinetochore
2.13 4.61e-04 GO:0046930 pore complex
1.84 6.59e-04 GO:0000793 condensed chromosome
1.30 1.33e-03 GO:0005794 Golgi apparatus
1.52 1.82e-03 GO:0005625 soluble fraction
3.26 3.07e-03 GO:0005839 proteasome core complex
2.68 4.68e-03 GO:0042641 actomyosin
1.47 5.13e-03 GO:0048471 perinuclear region of cytoplasm
2.83 5.35e-03 GO:0001725 stress fiber
1.83 5.46e-03 GO:0016607 nuclear speck
1.60 5.63e-03 GO:0005813 centrosome
1.33 7.28e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.07 7.41e-03 GO:0000777 condensed chromosome kinetochore
1.21 1.36e-02 GO:0005856 cytoskeleton
2.00 1.38e-02 GO:0000779 condensed chromosome, centromeric region
1.31 1.38e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.30 1.49e-02 GO:0031988 membrane-bounded vesicle
2.06 1.65e-02 GO:0034399 nuclear periphery
2.13 1.87e-02 GO:0030496 midbody
1.28 1.88e-02 GO:0005626 insoluble fraction
2.64 1.91e-02 GO:0032432 actin filament bundle
2.39 2.70e-02 GO:0000118 histone deacetylase complex
2.39 2.70e-02 GO:0005876 spindle microtubule
1.31 2.72e-02 GO:0005789 endoplasmic reticulum membrane
1.29 3.03e-02 GO:0044432 endoplasmic reticulum part
1.27 3.75e-02 GO:0005624 membrane fraction
2.28 4.44e-02 GO:0016469 proton-transporting two-sector ATPase complex
1.27 4.66e-02 GO:0031982 vesicle
1.28 4.99e-02 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 6.75e-114 GO:0005515 protein binding
1.17 1.21e-64 GO:0005488 binding
2.13 8.38e-51 GO:0003723 RNA binding
2.76 3.42e-20 GO:0003735 structural constituent of ribosome
1.39 4.00e-19 GO:0000166 nucleotide binding
1.61 1.76e-10 GO:0005198 structural molecule activity
1.17 2.05e-10 GO:0003824 catalytic activity
1.77 5.08e-10 GO:0003712 transcription cofactor activity
1.76 6.46e-10 GO:0000988 protein binding transcription factor activity
1.76 6.46e-10 GO:0000989 transcription factor binding transcription factor activity
1.23 1.26e-09 GO:0003676 nucleic acid binding
2.65 5.41e-09 GO:0008135 translation factor activity, nucleic acid binding
3.11 2.58e-08 GO:0003743 translation initiation factor activity
1.48 6.08e-08 GO:0019899 enzyme binding
3.14 1.48e-07 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.28 3.33e-07 GO:0003954 NADH dehydrogenase activity
3.28 3.33e-07 GO:0008137 NADH dehydrogenase (ubiquinone) activity
3.28 3.33e-07 GO:0050136 NADH dehydrogenase (quinone) activity
2.06 9.35e-07 GO:0003714 transcription corepressor activity
1.27 1.07e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.26 2.43e-06 GO:0017076 purine nucleotide binding
1.26 3.02e-06 GO:0032553 ribonucleotide binding
1.26 3.02e-06 GO:0032555 purine ribonucleotide binding
2.42 4.73e-06 GO:0003729 mRNA binding
2.36 1.24e-05 GO:0031625 ubiquitin protein ligase binding
1.28 1.75e-05 GO:0005524 ATP binding
1.27 2.71e-05 GO:0030554 adenyl nucleotide binding
1.27 2.79e-05 GO:0032559 adenyl ribonucleotide binding
2.97 2.52e-04 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
1.36 5.59e-04 GO:0017111 nucleoside-triphosphatase activity
1.35 6.91e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.35 7.71e-04 GO:0016462 pyrophosphatase activity
1.34 9.52e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.45 1.36e-03 GO:0016874 ligase activity
1.63 3.38e-03 GO:0003713 transcription coactivator activity
2.07 3.75e-03 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
1.32 7.83e-03 GO:0042802 identical protein binding
1.98 9.67e-03 GO:0035257 nuclear hormone receptor binding
2.51 1.14e-02 GO:0032182 small conjugating protein binding
1.97 1.43e-02 GO:0008565 protein transporter activity
2.21 1.50e-02 GO:0003697 single-stranded DNA binding
2.52 1.72e-02 GO:0043130 ubiquitin binding
1.82 2.19e-02 GO:0051082 unfolded protein binding
2.76 2.69e-02 GO:0046966 thyroid hormone receptor binding
2.33 3.29e-02 GO:0004812 aminoacyl-tRNA ligase activity
2.33 3.29e-02 GO:0016875 ligase activity, forming carbon-oxygen bonds
2.33 3.29e-02 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
1.84 4.70e-02 GO:0051427 hormone receptor binding