Motif ID: ZBTB6.p2

Z-value: 1.351


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB6chr9_-_125675571-0.152.7e-02Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_60337350 33.949 NM_021136
RTN1
reticulon 1
chr11_-_12030882 22.598 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr10_-_15413054 20.944 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr22_-_39240016 19.494 NM_014293
NPTXR
neuronal pentraxin receptor
chr11_-_12030838 18.548 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030539 18.297 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030622 17.531 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_43996478 13.237 NM_002840
NM_130440
PTPRF

protein tyrosine phosphatase, receptor type, F

chr9_+_87284625 12.046 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr4_+_41258941 11.613 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr17_-_42992852 11.507 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr5_+_17217474 11.408 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr4_+_41258909 11.269 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258895 11.047 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_+_17217781 10.939 BASP1
brain abundant, membrane attached signal protein 1
chr11_-_12030128 10.828 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr9_+_137979513 10.778 OLFM1
olfactomedin 1
chr19_+_36359346 10.581 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr3_-_58563490 10.159 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr8_+_104512975 10.056 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr14_+_29236882 10.035 FOXG1
forkhead box G1
chr11_+_65658101 9.276 CCDC85B
coiled-coil domain containing 85B
chr20_+_44035203 9.211 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr16_+_56659584 9.174 NM_175617
MT1E
metallothionein 1E
chr11_-_117747331 9.005 FXYD6
FXYD domain containing ion transport regulator 6
chr2_-_55277653 8.946 RTN4
reticulon 4
chr16_+_2039945 8.696 NM_004209
SYNGR3
synaptogyrin 3
chr16_+_56225301 8.687 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr2_-_55277421 8.662 RTN4
reticulon 4
chrX_-_92928566 8.008 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr9_+_34958320 7.993 KIAA1045
KIAA1045
chr4_+_1795004 7.887 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr12_+_79258588 7.787 SYT1
synaptotagmin I
chr19_-_36523770 7.631 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr11_-_119293848 7.614 THY1
Thy-1 cell surface antigen
chr11_+_46299554 7.453 CREB3L1
cAMP responsive element binding protein 3-like 1
chr8_+_61429390 7.444 NM_001242644
NM_002865
RAB2A

RAB2A, member RAS oncogene family

chr12_+_79258517 7.412 SYT1
synaptotagmin I
chr5_-_54830369 7.398 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr17_-_7518124 7.330 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr1_+_151032150 7.291 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_55277459 7.014 RTN4
reticulon 4
chr1_+_51701995 6.973 RNF11
ring finger protein 11
chr12_-_54982271 6.810 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr12_+_79258794 6.806 SYT1
synaptotagmin I
chr17_+_40118792 6.805 CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr3_+_147127151 6.754 NM_003412
ZIC1
Zic family member 1
chr6_-_3157696 6.746 NM_001069
TUBB2A
tubulin, beta 2A class IIa
chr5_-_151066492 6.705 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr2_-_55277672 6.685 RTN4
reticulon 4
chr13_+_27131879 6.547 WASF3
WAS protein family, member 3
chr2_-_55277698 6.461 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr3_+_159557649 6.436 NM_001197109
SCHIP1
schwannomin interacting protein 1
chrX_+_102632108 6.375 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_51701943 6.346 NM_014372
RNF11
ring finger protein 11
chr11_-_65382701 6.237 MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr15_+_64752778 6.199 ZNF609
zinc finger protein 609
chr19_-_36523540 6.086 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr12_-_52914080 6.071 NM_000424
KRT5
keratin 5
chr1_+_51701970 6.025 RNF11
ring finger protein 11
chr10_-_133795447 5.971 BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr5_-_176057324 5.958 NM_001001502
NM_003085
SNCB

synuclein, beta

chr5_-_151066445 5.904 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_+_159557745 5.779 SCHIP1
schwannomin interacting protein 1
chr5_+_140220811 5.746 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr11_-_61735108 5.572 NM_002032
FTH1
ferritin, heavy polypeptide 1
chr9_-_101470836 5.521 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_4304590 5.508 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr12_-_45270632 5.480 NM_001145107
NELL2
NEL-like 2 (chicken)
chr11_-_45687135 5.435 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr12_+_79258448 5.393 NM_005639
SYT1
synaptotagmin I
chr11_-_125366048 5.349 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr18_-_74691951 5.327 MBP
myelin basic protein
chr1_+_184356227 5.221 C1orf21
chromosome 1 open reading frame 21
chr12_+_119616594 5.188 NM_014365
HSPB8
heat shock 22kDa protein 8
chr16_+_56716378 5.186 NM_005952
MT1X
metallothionein 1X
chr13_+_27131799 5.133 NM_006646
WASF3
WAS protein family, member 3
chr6_-_46293404 5.131 RCAN2
regulator of calcineurin 2
chr6_+_41040713 5.121 NFYA
nuclear transcription factor Y, alpha
chr10_-_133795311 5.100 NM_004052
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr2_-_55277620 5.041 RTN4
reticulon 4
chr4_+_166128769 5.027 NM_007246
KLHL2
kelch-like 2, Mayven (Drosophila)
chr7_-_124405029 5.025 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_184356128 5.018 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr5_+_173472692 5.000 NM_015980
HMP19
HMP19 protein
chr11_-_35547144 4.968 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr15_+_80696569 4.964 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr3_+_181430075 4.937 SOX2
SRY (sex determining region Y)-box 2
chr15_+_84115979 4.911 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr2_+_187454724 4.908 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr1_+_204797774 4.899 NM_001005388
NM_001005389
NM_001160332
NM_001160333
NM_015090
NFASC




neurofascin




chr15_+_22892699 4.879 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr19_-_3700387 4.734 PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr15_-_83378488 4.684 NM_004644
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr2_-_55277592 4.682 RTN4
reticulon 4
chr6_-_88875766 4.640 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr6_-_6007097 4.634 NRN1
neuritin 1
chr11_+_63753827 4.624 OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr22_+_24373107 4.606 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr6_-_46293628 4.596 NM_005822
RCAN2
regulator of calcineurin 2
chr15_+_71184781 4.541 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr3_-_48130283 4.540 MAP4
microtubule-associated protein 4
chr6_-_116575170 4.539 NM_021648
TSPYL4
TSPY-like 4
chr11_+_46299161 4.495 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr22_-_21213012 4.421 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr22_+_26565424 4.407 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr22_+_41865112 4.398 NM_001098
ACO2
aconitase 2, mitochondrial
chr22_-_21213099 4.378 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_6007632 4.364 NM_016588
NRN1
neuritin 1
chr19_-_3700466 4.345 NM_001195733
NM_012398
PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

chr4_-_5828587 4.332 CRMP1
collapsin response mediator protein 1
chr19_+_54058493 4.323 NM_001079907
ZNF331
zinc finger protein 331
chr22_-_21213069 4.323 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr3_+_105085553 4.308 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr11_-_119294242 4.272 NM_006288
THY1
Thy-1 cell surface antigen
chr4_-_176734181 4.269 NM_201591
GPM6A
glycoprotein M6A
chr5_-_146257633 4.256 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_115152322 4.242 NM_001801
CDO1
cysteine dioxygenase, type I
chr20_-_48532036 4.195 SPATA2
spermatogenesis associated 2
chr3_-_48130633 4.192 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr12_-_96793797 4.189 CDK17
cyclin-dependent kinase 17
chr6_-_33168448 4.144 RXRB
retinoid X receptor, beta
chr11_+_46958228 4.142 NM_001003676
NM_001003677
NM_001003678
NM_024113
C11orf49



chromosome 11 open reading frame 49



chr5_+_141488314 4.140 NM_030571
NDFIP1
Nedd4 family interacting protein 1
chr1_+_50513685 4.116 NM_001144777
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_+_8768403 4.091 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr1_+_27648622 4.084 NM_032125
TMEM222
transmembrane protein 222
chr7_-_143059696 4.053 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr10_-_99790584 4.049 NM_001206528
NM_018058
CRTAC1

cartilage acidic protein 1

chr6_+_72892371 4.045 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_32229635 4.044 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr5_-_57755787 4.044 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr6_-_36953942 4.038 MTCH1
mitochondrial carrier 1
chr1_-_223537400 4.024 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr11_+_73019662 4.018 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr14_+_105781180 4.011 PACS2
phosphofurin acidic cluster sorting protein 2
chrX_-_51239426 4.008 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_6533758 3.988 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_-_48931645 3.981 NM_007213
PRAF2
PRA1 domain family, member 2
chr22_-_36019363 3.975 NM_203377
MB
myoglobin
chr11_+_117070039 3.969 NM_001001522
NM_003186
TAGLN

transgelin

chr17_-_49198084 3.946 NM_001130527
NM_001130528
NM_003971
SPAG9


sperm associated antigen 9


chr4_+_30722191 3.927 PCDH7
protocadherin 7
chr11_-_695161 3.914 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr12_+_110719143 3.888 ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr20_+_30102261 3.875 HM13
histocompatibility (minor) 13
chr4_+_166128823 3.870 KLHL2
kelch-like 2, Mayven (Drosophila)
chr16_+_56225250 3.845 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr11_-_61735067 3.808 FTH1
CPSF7
ferritin, heavy polypeptide 1
cleavage and polyadenylation specific factor 7, 59kDa
chr1_+_27648721 3.808 TMEM222
transmembrane protein 222
chr1_-_59248287 3.804 JUN
jun proto-oncogene
chr17_-_7517849 3.801 FXR2
fragile X mental retardation, autosomal homolog 2
chr5_+_141488385 3.768 NDFIP1
Nedd4 family interacting protein 1
chr13_+_42031525 3.755 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr16_-_53537112 3.750 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr11_-_695010 3.750 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr20_+_30102237 3.750 NM_030789
NM_178580
NM_178581
NM_178582
HM13



histocompatibility (minor) 13



chr11_-_695402 3.749 NM_021008
DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr5_-_171433502 3.747 FBXW11
F-box and WD repeat domain containing 11
chr6_-_33168369 3.743 NM_021976
RXRB
retinoid X receptor, beta
chr6_-_116601085 3.729 TSPYL1
TSPY-like 1
chr1_+_163038934 3.728 NM_001113381
RGS4
regulator of G-protein signaling 4
chr19_+_1104614 3.727 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr19_+_35634153 3.708 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr20_-_32031425 3.693 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr8_+_61429724 3.688 RAB2A
RAB2A, member RAS oncogene family
chr6_-_36953946 3.668 NM_014341
MTCH1
mitochondrial carrier 1
chr3_+_112052020 3.666 CD200
CD200 molecule
chr19_-_46974789 3.665 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr2_-_220174058 3.654 PTPRN
protein tyrosine phosphatase, receptor type, N
chr14_+_24540742 3.634 NM_006032
CPNE6
copine VI (neuronal)
chr12_+_50898744 3.628 NM_173602
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr20_+_10199455 3.626 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr22_-_20104745 3.624 NM_022727
NM_182984
TRMT2A

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

chr5_+_141488384 3.617 NDFIP1
Nedd4 family interacting protein 1
chr3_-_62861012 3.603 NM_003716
NM_183393
NM_183394
CADPS


Ca++-dependent secretion activator


chr3_-_33759540 3.596 CLASP2
cytoplasmic linker associated protein 2
chr3_-_33759684 3.591 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr1_+_1981902 3.589 NM_002744
PRKCZ
protein kinase C, zeta
chr2_+_220144024 3.567 NM_001039550
NM_006736
DNAJB2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr2_-_55276288 3.564 NM_207521
RTN4
reticulon 4
chr1_+_86046434 3.542 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr14_+_59104736 3.534 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr17_+_7608413 3.524 NM_001406
EFNB3
ephrin-B3
chr2_-_132121730 3.518 NM_001077637
WTH3DI
RAB6C-like
chr1_+_155293727 3.509 NM_001105205
RUSC1
RUN and SH3 domain containing 1
chr12_+_121078421 3.492 NM_001033677
CABP1
calcium binding protein 1
chr5_+_140346053 3.473 PCDHAC2
protocadherin alpha subfamily C, 2
chr11_+_63753902 3.467 OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr7_+_75677402 3.461 MDH2
malate dehydrogenase 2, NAD (mitochondrial)
chr3_-_38066277 3.452 NM_001130964
PLCD1
phospholipase C, delta 1
chr2_+_230787195 3.438 NM_174899
FBXO36
F-box protein 36
chr3_-_120068077 3.414 NM_001099678
LRRC58
leucine rich repeat containing 58
chr19_-_4400470 3.408 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr11_-_64490654 3.406 NM_015080
NM_138732
NRXN2

neurexin 2

chr7_+_148982371 3.382 LOC155060
AI894139 pseudogene
chr3_-_49761293 3.380 NM_013334
NM_021971
GMPPB

GDP-mannose pyrophosphorylase B

chr6_-_36953924 3.348 MTCH1
mitochondrial carrier 1
chr11_-_695069 3.336 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr20_+_5891973 3.332 NM_001819
CHGB
chromogranin B (secretogranin 1)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.84 4.93e-22 GO:0007399 nervous system development
1.17 1.27e-21 GO:0009987 cellular process
1.24 2.02e-17 GO:0065007 biological regulation
1.47 3.24e-17 GO:0048856 anatomical structure development
1.42 7.86e-17 GO:0023052 signaling
1.25 3.58e-16 GO:0050789 regulation of biological process
1.25 3.76e-15 GO:0050794 regulation of cellular process
1.47 1.13e-14 GO:0048731 system development
1.39 1.90e-14 GO:0032502 developmental process
1.39 1.29e-12 GO:0007275 multicellular organismal development
1.83 2.82e-11 GO:0048699 generation of neurons
1.80 3.32e-11 GO:0022008 neurogenesis
2.12 4.91e-11 GO:0019226 transmission of nerve impulse
2.12 4.91e-11 GO:0035637 multicellular organismal signaling
1.37 5.49e-11 GO:0007165 signal transduction
1.49 8.30e-11 GO:0048869 cellular developmental process
1.49 2.49e-10 GO:0030154 cell differentiation
2.12 1.68e-09 GO:0007268 synaptic transmission
1.82 1.78e-08 GO:0030182 neuron differentiation
1.31 8.82e-08 GO:0051179 localization
1.67 1.51e-07 GO:0048468 cell development
1.23 4.03e-07 GO:0032501 multicellular organismal process
1.47 4.57e-07 GO:0023051 regulation of signaling
1.30 5.49e-07 GO:0016043 cellular component organization
1.61 9.21e-07 GO:0007154 cell communication
1.37 1.33e-06 GO:0048519 negative regulation of biological process
1.26 1.58e-06 GO:0051716 cellular response to stimulus
1.87 2.12e-06 GO:0048858 cell projection morphogenesis
1.50 3.28e-06 GO:0035556 intracellular signal transduction
1.86 3.45e-06 GO:0032990 cell part morphogenesis
1.85 3.89e-06 GO:0007417 central nervous system development
1.38 4.19e-06 GO:0048523 negative regulation of cellular process
1.92 4.60e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.91 5.05e-06 GO:0048812 neuron projection morphogenesis
1.46 6.73e-06 GO:0009653 anatomical structure morphogenesis
1.92 8.57e-06 GO:0007409 axonogenesis
1.27 1.23e-05 GO:0071840 cellular component organization or biogenesis
1.30 1.25e-05 GO:0051234 establishment of localization
1.76 1.63e-05 GO:0048666 neuron development
1.65 1.96e-05 GO:0016192 vesicle-mediated transport
1.71 2.44e-05 GO:0030030 cell projection organization
1.30 2.56e-05 GO:0006810 transport
1.18 2.75e-05 GO:0050896 response to stimulus
1.64 2.82e-05 GO:0007267 cell-cell signaling
1.58 3.69e-05 GO:0050793 regulation of developmental process
1.81 3.69e-05 GO:0031175 neuron projection development
1.70 3.73e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.64 4.74e-05 GO:2000026 regulation of multicellular organismal development
1.47 5.29e-05 GO:0051239 regulation of multicellular organismal process
2.07 7.03e-05 GO:0010035 response to inorganic substance
2.07 7.03e-05 GO:0051960 regulation of nervous system development
1.44 1.08e-04 GO:0009966 regulation of signal transduction
1.65 1.21e-04 GO:0045595 regulation of cell differentiation
1.70 1.28e-04 GO:0000902 cell morphogenesis
1.77 1.33e-04 GO:0000904 cell morphogenesis involved in differentiation
1.75 1.45e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.67 1.55e-04 GO:0032989 cellular component morphogenesis
1.92 3.44e-04 GO:0007411 axon guidance
1.36 3.57e-04 GO:0048583 regulation of response to stimulus
1.22 5.83e-04 GO:0019222 regulation of metabolic process
1.29 6.33e-04 GO:0071842 cellular component organization at cellular level
1.35 6.33e-04 GO:0006464 protein modification process
1.28 8.49e-04 GO:0048518 positive regulation of biological process
2.50 1.03e-03 GO:0010975 regulation of neuron projection development
1.23 1.32e-03 GO:0031323 regulation of cellular metabolic process
1.53 1.52e-03 GO:0051128 regulation of cellular component organization
2.13 1.61e-03 GO:0045664 regulation of neuron differentiation
1.34 2.02e-03 GO:0007166 cell surface receptor linked signaling pathway
1.51 2.44e-03 GO:0040011 locomotion
2.20 2.71e-03 GO:0010038 response to metal ion
1.22 2.87e-03 GO:0080090 regulation of primary metabolic process
1.99 2.92e-03 GO:0050767 regulation of neurogenesis
1.47 3.15e-03 GO:0032879 regulation of localization
1.45 3.33e-03 GO:0010646 regulation of cell communication
1.86 3.53e-03 GO:0060284 regulation of cell development
1.30 3.95e-03 GO:0065008 regulation of biological quality
1.82 4.58e-03 GO:0044057 regulation of system process
1.45 5.02e-03 GO:0006793 phosphorus metabolic process
1.45 5.02e-03 GO:0006796 phosphate metabolic process
1.90 5.11e-03 GO:0061061 muscle structure development
1.28 5.79e-03 GO:0042221 response to chemical stimulus
1.53 6.11e-03 GO:0006468 protein phosphorylation
1.31 7.42e-03 GO:0043412 macromolecule modification
1.77 8.47e-03 GO:0007420 brain development
1.68 1.01e-02 GO:0051094 positive regulation of developmental process
1.25 1.14e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.26 1.15e-02 GO:0048522 positive regulation of cellular process
2.20 1.24e-02 GO:0031344 regulation of cell projection organization
1.67 1.35e-02 GO:0061024 membrane organization
1.35 1.61e-02 GO:0065009 regulation of molecular function
1.45 1.74e-02 GO:0031324 negative regulation of cellular metabolic process
1.65 2.11e-02 GO:0016044 cellular membrane organization
1.46 3.29e-02 GO:0016310 phosphorylation
1.92 3.39e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.74 3.56e-02 GO:0045597 positive regulation of cell differentiation
1.41 4.01e-02 GO:0009605 response to external stimulus
2.24 4.02e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.26 4.56e-02 GO:0050890 cognition
2.22 4.80e-02 GO:0022604 regulation of cell morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.40 3.05e-08 GO:0044459 plasma membrane part
1.89 4.57e-06 GO:0043005 neuron projection
1.68 1.95e-05 GO:0030054 cell junction
1.21 6.08e-05 GO:0071944 cell periphery
1.21 6.43e-05 GO:0005886 plasma membrane
1.79 8.04e-05 GO:0045202 synapse
1.12 8.82e-05 GO:0005737 cytoplasm
1.41 2.18e-04 GO:0031226 intrinsic to plasma membrane
2.15 3.99e-04 GO:0030424 axon
2.58 4.88e-04 GO:0019717 synaptosome
1.40 5.37e-04 GO:0005887 integral to plasma membrane
1.49 5.47e-04 GO:0005626 insoluble fraction
1.96 8.23e-04 GO:0016323 basolateral plasma membrane
1.12 1.02e-03 GO:0016020 membrane
1.49 1.19e-03 GO:0005624 membrane fraction
1.75 1.36e-03 GO:0048471 perinuclear region of cytoplasm
2.89 2.04e-03 GO:0030426 growth cone
1.39 2.80e-03 GO:0000267 cell fraction
1.47 3.28e-03 GO:0031982 vesicle
2.80 3.52e-03 GO:0030427 site of polarized growth
1.44 3.52e-03 GO:0042995 cell projection
1.69 3.64e-03 GO:0009986 cell surface
1.54 4.43e-03 GO:0044431 Golgi apparatus part
1.47 4.60e-03 GO:0031410 cytoplasmic vesicle
1.07 5.40e-03 GO:0044424 intracellular part
2.03 7.35e-03 GO:0070161 anchoring junction
2.07 1.00e-02 GO:0005912 adherens junction
1.39 1.02e-02 GO:0005794 Golgi apparatus
1.07 1.53e-02 GO:0005622 intracellular
1.44 1.80e-02 GO:0031988 membrane-bounded vesicle
1.44 2.01e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.68 3.69e-02 GO:0044456 synapse part
2.43 3.73e-02 GO:0033267 axon part
1.28 4.03e-02 GO:0005856 cytoskeleton
2.22 4.18e-02 GO:0005925 focal adhesion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 1.49e-13 GO:0005515 protein binding
1.11 7.49e-10 GO:0005488 binding
1.74 1.11e-05 GO:0008092 cytoskeletal protein binding
1.71 7.38e-04 GO:0019904 protein domain specific binding
1.40 1.01e-02 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.01e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.09 2.50e-02 GO:0005516 calmodulin binding
3.87 3.37e-02 GO:0004112 cyclic-nucleotide phosphodiesterase activity
1.42 3.50e-02 GO:0016301 kinase activity
1.44 3.63e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor