Motif ID: ZNF143.p2

Z-value: 5.327


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF143chr11_+_94825110.583.6e-21Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_1723212 134.977 NM_006342
TACC3
transforming, acidic coiled-coil containing protein 3
chr17_-_47492215 128.301 PHB
prohibitin
chr20_-_32891075 116.312 NM_000687
AHCY
adenosylhomocysteinase
chr12_+_56498324 109.260 PA2G4
proliferation-associated 2G4, 38kDa
chr12_+_56498347 107.642 PA2G4
proliferation-associated 2G4, 38kDa
chr15_+_40453263 107.174 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr15_+_40453209 104.125 NM_001211
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr19_-_48673559 101.616 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr12_+_32832128 96.640 NM_005690
NM_012062
NM_012063
DNM1L


dynamin 1-like


chr1_-_54304107 96.112 NM_001168551
NM_018087
TMEM48

transmembrane protein 48

chrY_+_59213948 95.454 NM_001145149
NM_001185183
NM_005638
VAMP7


vesicle-associated membrane protein 7


chrX_+_155110942 93.306 NM_001145149
NM_001185183
NM_005638
VAMP7


vesicle-associated membrane protein 7


chr12_+_56498102 90.909 NM_006191
PA2G4
proliferation-associated 2G4, 38kDa
chr17_-_47492216 89.496 NM_002634
PHB
prohibitin
chr11_-_82997376 89.069 NM_021825
CCDC90B
coiled-coil domain containing 90B
chr12_+_56498414 87.077 PA2G4
proliferation-associated 2G4, 38kDa
chr12_+_32832209 80.578 DNM1L
dynamin 1-like
chr4_+_1723233 80.417 TACC3
transforming, acidic coiled-coil containing protein 3
chr11_-_82996898 80.222 CCDC90B
coiled-coil domain containing 90B
chr10_+_124913884 79.841 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr12_+_56498365 79.401 PA2G4
proliferation-associated 2G4, 38kDa
chr12_+_32832272 78.648 DNM1L
dynamin 1-like
chr13_-_50367027 77.435 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr17_+_76210276 76.807 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chr22_-_41682169 76.560 RANGAP1
Ran GTPase activating protein 1
chr22_+_30163351 76.385 NM_001003684
NM_013387
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr1_+_45205533 75.597 KIF2C
kinesin family member 2C
chr1_+_224544590 74.775 NM_014184
CNIH4
cornichon homolog 4 (Drosophila)
chr22_-_41682187 72.457 NM_002883
RANGAP1
Ran GTPase activating protein 1
chr12_+_56498334 71.578 PA2G4
proliferation-associated 2G4, 38kDa
chr1_+_224544550 71.555 CNIH4
cornichon homolog 4 (Drosophila)
chr17_+_76210329 71.155 BIRC5
baculoviral IAP repeat containing 5
chr19_+_12917391 70.954 RNASEH2A
ribonuclease H2, subunit A
chr9_-_116172658 70.792 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr1_+_224544597 69.452 CNIH4
cornichon homolog 4 (Drosophila)
chr1_+_45205558 68.921 KIF2C
kinesin family member 2C
chr4_-_2965036 68.308 NOP14
NOP14 nucleolar protein homolog (yeast)
chr1_-_54303933 67.525 TMEM48
transmembrane protein 48
chr17_-_5322982 67.285 NM_002532
NUP88
nucleoporin 88kDa
chr19_+_54618789 66.037 NM_015629
PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_-_2456954 64.680 NM_032737
LMNB2
lamin B2
chr9_-_116172635 64.582 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr14_-_23398605 63.505 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr14_-_23398563 63.454 PRMT5
protein arginine methyltransferase 5
chr12_-_122985471 63.405 NM_017612
ZCCHC8
zinc finger, CCHC domain containing 8
chr14_+_97263681 63.349 NM_003384
VRK1
vaccinia related kinase 1
chr12_+_53895376 62.805 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr1_+_156024516 61.736 NM_001145264
NM_014017
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr20_-_47804903 60.382 NM_001037328
NM_004602
NM_017452
NM_017453
NM_017454
STAU1




staufen, RNA binding protein, homolog 1 (Drosophila)




chr9_-_116172572 60.204 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr19_+_41257086 58.420 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr4_-_2965091 56.930 NOP14
NOP14 nucleolar protein homolog (yeast)
chr3_+_133524671 56.114 SRPRB
signal recognition particle receptor, B subunit
chr7_-_150754934 55.608 CDK5
cyclin-dependent kinase 5
chr10_+_124913921 55.288 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr22_-_36925212 54.960 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr11_+_64808375 54.897 NM_013299
SAC3D1
SAC3 domain containing 1
chr4_-_2965111 54.893 NM_003703
NOP14
NOP14 nucleolar protein homolog (yeast)
chr1_+_45205466 54.446 NM_006845
KIF2C
kinesin family member 2C
chr11_+_16760147 54.332 NM_014267
C11orf58
chromosome 11 open reading frame 58
chr1_-_197115566 54.280 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr3_+_133524636 54.122 SRPRB
signal recognition particle receptor, B subunit
chr20_-_48732479 53.980 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr7_-_99063763 53.953 NM_001198879
NM_001003713
NM_001003714
NM_001039178
NM_004889
ATP5J2-PTCD1
ATP5J2



ATP5J2-PTCD1 readthrough
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2



chr8_-_144699716 53.946 NM_003313
TSTA3
tissue specific transplantation antigen P35B
chr17_+_30771520 53.666 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_62777621 53.008 LOC146880
Rho GTPase activating protein 27 pseudogene
chr10_+_124913759 52.792 NM_001007793
NM_004725
BUB3

budding uninhibited by benzimidazoles 3 homolog (yeast)

chr12_-_96429296 52.709 NM_000895
LTA4H
leukotriene A4 hydrolase
chr7_-_150754979 52.558 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr11_+_16760175 52.503 C11orf58
chromosome 11 open reading frame 58
chr8_-_144699621 51.715 TSTA3
tissue specific transplantation antigen P35B
chr5_+_85913762 51.613 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr11_+_64808395 51.042 SAC3D1
SAC3 domain containing 1
chr17_-_21117647 50.969 TMEM11
transmembrane protein 11
chr1_+_38158129 50.430 NM_018101
CDCA8
cell division cycle associated 8
chr16_-_12009734 50.350 GSPT1
G1 to S phase transition 1
chr12_-_96429397 50.101 LTA4H
leukotriene A4 hydrolase
chr22_-_36925138 49.976 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr3_-_186524226 49.874 NM_002916
RFC4
replication factor C (activator 1) 4, 37kDa
chr8_-_144699695 49.831 TSTA3
tissue specific transplantation antigen P35B
chr10_-_13390018 49.805 SEPHS1
selenophosphate synthetase 1
chr22_-_36925270 49.716 NM_003753
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr3_-_186524483 49.334 NM_181573
RFC4
replication factor C (activator 1) 4, 37kDa
chr1_-_67896081 49.196 SERBP1
SERPINE1 mRNA binding protein 1
chr19_+_12917409 48.595 NM_006397
RNASEH2A
ribonuclease H2, subunit A
chr1_+_156737315 48.417 PRCC
papillary renal cell carcinoma (translocation-associated)
chr11_-_60674039 47.890 NM_014502
PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr16_-_31106049 47.876 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr14_-_105487421 47.527 NM_017955
NM_145701
CDCA4

cell division cycle associated 4

chr17_+_66031814 47.418 NM_002266
KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr12_+_56435685 47.135 NM_001029
RPS26
ribosomal protein S26
chr11_-_64578017 46.899 NM_130800
NM_130801
MEN1

multiple endocrine neoplasia I

chr19_-_47354060 46.453 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chrX_+_48334400 46.426 NM_012280
NM_177439
FTSJ1

FtsJ homolog 1 (E. coli)

chr3_-_167452593 45.879 NM_007217
NM_145860
NM_145859
PDCD10


programmed cell death 10


chr17_+_66031885 45.604 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_2394546 45.530 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr22_-_36925175 44.751 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr17_-_21117899 44.556 NM_003876
TMEM11
transmembrane protein 11
chr11_+_208529 44.553 NM_021932
RIC8A
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
chr20_-_47804675 44.430 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr6_-_5004238 44.406 NM_006638
RPP40
ribonuclease P/MRP 40kDa subunit
chr5_+_137514416 44.289 NM_005733
KIF20A
kinesin family member 20A
chr1_-_67896098 43.938 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr21_-_30445949 43.914 CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr7_+_150755298 43.722 NM_001199692
SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr5_+_85913755 43.511 COX7C
cytochrome c oxidase subunit VIIc
chr12_-_122985396 43.420 ZCCHC8
zinc finger, CCHC domain containing 8
chr21_-_30445913 43.272 CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr9_-_116172951 43.219 NM_017443
POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr17_-_21117479 43.129 TMEM11
transmembrane protein 11
chr10_+_124913862 43.057 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr7_-_96339074 42.847 SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr8_-_63951353 41.875 GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr16_+_3074027 41.807 NM_001142350
NM_024339
THOC6

THO complex 6 homolog (Drosophila)

chr6_+_56954978 41.764 ZNF451
zinc finger protein 451
chr12_+_53895065 41.565 TARBP2
TAR (HIV-1) RNA binding protein 2
chr2_-_74756824 41.390 AUP1
ancient ubiquitous protein 1
chr5_+_137514753 41.317 KIF20A
kinesin family member 20A
chr2_-_242447919 41.212 STK25
serine/threonine kinase 25
chr1_+_156737273 41.039 NM_005973
PRCC
papillary renal cell carcinoma (translocation-associated)
chr9_+_116037955 40.992 PRPF4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr12_+_88536045 40.950 NM_181783
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr7_+_2394428 40.892 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr2_-_132249946 40.603 MZT2A
mitotic spindle organizing protein 2A
chr11_-_64578176 40.469 NM_000244
NM_130799
NM_130802
MEN1


multiple endocrine neoplasia I


chr12_+_93861265 40.446 NM_014050
NM_172177
MRPL42

mitochondrial ribosomal protein L42

chr12_-_2986095 40.206 FOXM1
forkhead box M1
chr8_-_63951609 40.072 NM_003878
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr7_+_2394508 39.897 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr12_+_57881853 39.849 MARS
methionyl-tRNA synthetase
chr3_+_160117444 39.626 SMC4
structural maintenance of chromosomes 4
chr20_-_61847446 39.621 NM_017798
YTHDF1
YTH domain family, member 1
chr1_-_67896097 39.600 SERBP1
SERPINE1 mRNA binding protein 1
chr1_+_38158176 38.965 CDCA8
cell division cycle associated 8
chr12_+_104609501 38.963 NM_001093771
TXNRD1
thioredoxin reductase 1
chr1_-_67896066 38.700 SERBP1
SERPINE1 mRNA binding protein 1
chr2_+_130939781 38.572 MZT2B
mitotic spindle organizing protein 2B
chr19_+_3185860 38.245 NM_020170
NCLN
nicalin
chr12_-_57146081 38.191 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr11_+_61560352 38.139 FEN1
flap structure-specific endonuclease 1
chr11_+_747428 38.127 NM_006755
TALDO1
transaldolase 1
chr12_-_46663207 37.988 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr6_+_56954801 37.973 NM_001031623
NM_015555
ZNF451

zinc finger protein 451

chr6_+_56954985 37.838 ZNF451
zinc finger protein 451
chr7_+_2394498 37.837 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr16_+_67880784 37.806 NM_005796
NUTF2
nuclear transport factor 2
chr14_+_77924367 37.525 NM_012111
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr17_-_40950682 37.311 NM_001040431
CCDC56
coiled-coil domain containing 56
chr16_+_3074041 37.275 THOC6
THO complex 6 homolog (Drosophila)
chr1_+_244816349 37.230 NM_016076
PPPDE1
PPPDE peptidase domain containing 1
chr16_+_577833 37.017 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chr12_+_64798050 37.005 NM_007235
XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr22_+_21922020 36.823 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr11_+_747424 36.391 TALDO1
transaldolase 1
chr2_+_86333304 36.287 NM_017952
PTCD3
Pentatricopeptide repeat domain 3
chr14_+_77924415 36.236 AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr19_+_50180492 36.181 PRMT1
protein arginine methyltransferase 1
chr16_+_3074060 35.857 THOC6
THO complex 6 homolog (Drosophila)
chr22_+_21922026 35.782 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr16_-_31106125 35.702 NM_024006
NM_206824
VKORC1

vitamin K epoxide reductase complex, subunit 1

chr1_+_19578288 35.532 MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr10_+_94352809 35.378 NM_004523
KIF11
kinesin family member 11
chr22_+_24951954 35.351 SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr17_-_5322870 35.318 NUP88
nucleoporin 88kDa
chr1_+_19578039 35.182 NM_016183
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr22_+_21922004 35.038 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr11_-_134123138 34.827 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
THYN1




thymocyte nuclear protein 1




chr8_+_145149978 34.759 CYC1
cytochrome c-1
chr4_+_140222668 34.583 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr10_+_94352873 34.475 KIF11
kinesin family member 11
chr16_+_23690234 34.352 PLK1
polo-like kinase 1
chr14_-_24701472 34.349 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr12_-_46662779 34.230 SLC38A1
solute carrier family 38, member 1
chr11_+_61560108 34.039 NM_004111
FEN1
flap structure-specific endonuclease 1
chr7_-_132766834 34.000 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr7_-_132766697 33.953 NM_017812
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_-_27593312 33.813 NM_001034116
NM_015636
EIF2B4

eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa

chr12_-_2986299 33.731 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr1_-_186344383 33.689 TPR
translocated promoter region (to activated MET oncogene)
chr19_+_50180408 33.636 NM_001207042
NM_001536
NM_198318
PRMT1


protein arginine methyltransferase 1


chr8_+_145149985 33.620 CYC1
cytochrome c-1
chr11_-_122932806 33.573 HSPA8
heat shock 70kDa protein 8
chr17_+_30771522 33.544 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_-_24701559 33.522 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr3_+_127771126 33.064 NM_013336
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr16_+_3074051 32.895 THOC6
THO complex 6 homolog (Drosophila)
chr18_+_34409058 32.842 NM_020776
KIAA1328
KIAA1328
chr19_-_1095380 32.750 NM_002695
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr4_-_174255454 32.539 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr22_+_24951923 32.271 SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr1_+_38158189 32.268 CDCA8
cell division cycle associated 8
chr1_-_26232890 32.245 NM_001145454
NM_005563
STMN1

stathmin 1

chr19_+_17378148 32.206 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr17_+_30771532 32.206 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr12_-_46662709 32.124 SLC38A1
solute carrier family 38, member 1
chr11_+_67374322 31.971 NM_001166102
NM_007103
NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

chr12_+_57881735 31.765 NM_004990
MARS
methionyl-tRNA synthetase
chr20_-_524335 31.716 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.52 1.46e-33 GO:0044237 cellular metabolic process
1.42 5.47e-28 GO:0008152 metabolic process
1.62 7.30e-28 GO:0044260 cellular macromolecule metabolic process
1.84 1.19e-26 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.69e-26 GO:0044238 primary metabolic process
1.73 1.48e-24 GO:0034641 cellular nitrogen compound metabolic process
1.71 2.20e-24 GO:0006807 nitrogen compound metabolic process
1.90 3.71e-23 GO:0090304 nucleic acid metabolic process
1.51 1.32e-22 GO:0043170 macromolecule metabolic process
1.94 1.21e-18 GO:0016070 RNA metabolic process
1.20 3.23e-18 GO:0009987 cellular process
1.68 2.90e-17 GO:0071841 cellular component organization or biogenesis at cellular level
1.86 5.73e-17 GO:0010467 gene expression
2.58 9.24e-15 GO:0000278 mitotic cell cycle
1.65 9.50e-15 GO:0071842 cellular component organization at cellular level
2.61 5.47e-14 GO:0016071 mRNA metabolic process
1.84 6.71e-14 GO:0006996 organelle organization
1.52 1.58e-13 GO:0071840 cellular component organization or biogenesis
3.74 1.74e-13 GO:0000375 RNA splicing, via transesterification reactions
2.41 3.77e-13 GO:0006396 RNA processing
3.09 1.87e-12 GO:0008380 RNA splicing
3.61 6.14e-12 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.61 6.14e-12 GO:0000398 nuclear mRNA splicing, via spliceosome
2.72 6.98e-12 GO:0016032 viral reproduction
3.47 9.53e-12 GO:0000075 cell cycle checkpoint
2.28 1.08e-11 GO:0022403 cell cycle phase
3.41 1.14e-11 GO:0071156 regulation of cell cycle arrest
2.01 1.23e-11 GO:0007049 cell cycle
2.15 2.06e-11 GO:0022402 cell cycle process
2.85 2.41e-11 GO:0010564 regulation of cell cycle process
1.49 2.44e-11 GO:0016043 cellular component organization
3.48 1.04e-10 GO:0022613 ribonucleoprotein complex biogenesis
1.57 1.23e-10 GO:0044267 cellular protein metabolic process
1.73 1.73e-10 GO:0034645 cellular macromolecule biosynthetic process
2.46 2.24e-10 GO:0034621 cellular macromolecular complex subunit organization
1.58 3.04e-10 GO:0044249 cellular biosynthetic process
2.65 3.62e-10 GO:0006397 mRNA processing
1.71 5.24e-10 GO:0009059 macromolecule biosynthetic process
3.31 7.95e-10 GO:0071843 cellular component biogenesis at cellular level
1.86 1.46e-09 GO:0044248 cellular catabolic process
2.22 1.65e-09 GO:0051726 regulation of cell cycle
2.91 4.89e-09 GO:0007346 regulation of mitotic cell cycle
1.53 6.13e-09 GO:0009058 biosynthetic process
2.72 2.93e-08 GO:0051329 interphase of mitotic cell cycle
2.67 5.95e-08 GO:0051325 interphase
2.66 6.84e-08 GO:0006412 translation
1.95 8.11e-08 GO:0043933 macromolecular complex subunit organization
1.45 8.53e-08 GO:0019538 protein metabolic process
3.65 1.95e-07 GO:0007093 mitotic cell cycle checkpoint
1.73 8.64e-07 GO:0044085 cellular component biogenesis
2.14 1.18e-06 GO:0044265 cellular macromolecule catabolic process
4.12 1.47e-06 GO:0071826 ribonucleoprotein complex subunit organization
4.19 2.09e-06 GO:0022618 ribonucleoprotein complex assembly
1.63 2.51e-06 GO:0009056 catabolic process
1.68 3.25e-06 GO:0051641 cellular localization
1.85 1.28e-05 GO:0046907 intracellular transport
2.16 2.05e-05 GO:0000279 M phase
2.42 2.33e-05 GO:0000087 M phase of mitotic cell cycle
2.41 2.62e-05 GO:0048285 organelle fission
3.99 2.87e-05 GO:0000216 M/G1 transition of mitotic cell cycle
6.01 3.77e-05 GO:0000245 spliceosome assembly
3.25 4.83e-05 GO:0045333 cellular respiration
3.41 5.37e-05 GO:0000084 S phase of mitotic cell cycle
1.92 6.65e-05 GO:0009057 macromolecule catabolic process
3.06 6.89e-05 GO:0000082 G1/S transition of mitotic cell cycle
2.39 7.24e-05 GO:0000280 nuclear division
2.39 7.24e-05 GO:0007067 mitosis
2.23 7.42e-05 GO:0034622 cellular macromolecular complex assembly
3.35 8.05e-05 GO:0051320 S phase
2.75 8.54e-05 GO:0022411 cellular component disassembly
2.75 8.54e-05 GO:0071845 cellular component disassembly at cellular level
2.37 9.10e-05 GO:0006366 transcription from RNA polymerase II promoter
4.05 1.03e-04 GO:0051352 negative regulation of ligase activity
4.05 1.03e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
3.26 1.45e-04 GO:0031570 DNA integrity checkpoint
1.58 1.90e-04 GO:0033036 macromolecule localization
2.39 1.98e-04 GO:0034660 ncRNA metabolic process
2.85 2.23e-04 GO:0010498 proteasomal protein catabolic process
2.85 2.23e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.72 2.40e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
4.01 2.53e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.83 2.60e-04 GO:0031400 negative regulation of protein modification process
1.67 4.54e-04 GO:0032774 RNA biosynthetic process
1.63 4.63e-04 GO:0008104 protein localization
3.46 4.74e-04 GO:0051438 regulation of ubiquitin-protein ligase activity
2.20 4.79e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.61 5.27e-04 GO:0051649 establishment of localization in cell
2.21 5.47e-04 GO:0019941 modification-dependent protein catabolic process
3.68 5.79e-04 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.76 6.45e-04 GO:0071844 cellular component assembly at cellular level
2.20 6.68e-04 GO:0043632 modification-dependent macromolecule catabolic process
2.16 8.59e-04 GO:0044257 cellular protein catabolic process
1.85 1.03e-03 GO:0006259 DNA metabolic process
3.31 1.07e-03 GO:0051340 regulation of ligase activity
3.42 1.12e-03 GO:0031397 negative regulation of protein ubiquitination
1.61 1.22e-03 GO:0022607 cellular component assembly
1.76 1.31e-03 GO:0065003 macromolecular complex assembly
2.16 1.91e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.80 2.28e-03 GO:0051276 chromosome organization
3.07 2.47e-03 GO:0000077 DNA damage checkpoint
2.90 2.65e-03 GO:0006403 RNA localization
3.04 2.94e-03 GO:0032984 macromolecular complex disassembly
3.04 2.94e-03 GO:0034623 cellular macromolecular complex disassembly
3.23 2.99e-03 GO:0022904 respiratory electron transport chain
3.45 3.33e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.59 3.34e-03 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.02 3.49e-03 GO:0051028 mRNA transport
2.45 3.49e-03 GO:0006457 protein folding
1.86 3.59e-03 GO:0006974 response to DNA damage stimulus
1.79 4.58e-03 GO:0071822 protein complex subunit organization
2.88 4.96e-03 GO:0050657 nucleic acid transport
2.88 4.96e-03 GO:0050658 RNA transport
2.88 4.96e-03 GO:0051236 establishment of RNA localization
3.32 6.12e-03 GO:0007088 regulation of mitosis
3.32 6.12e-03 GO:0051783 regulation of nuclear division
2.02 6.17e-03 GO:0030163 protein catabolic process
3.28 7.44e-03 GO:0051351 positive regulation of ligase activity
2.97 7.76e-03 GO:0090068 positive regulation of cell cycle process
3.71 7.81e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.71 7.81e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
3.71 7.81e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
3.71 7.81e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
3.71 7.81e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
3.71 7.81e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
3.71 7.81e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
3.71 7.81e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.62 8.32e-03 GO:0045184 establishment of protein localization
3.24 9.01e-03 GO:0019080 viral genome expression
3.24 9.01e-03 GO:0019083 viral transcription
3.86 9.26e-03 GO:0046782 regulation of viral transcription
3.65 9.84e-03 GO:0048524 positive regulation of viral reproduction
4.05 1.06e-02 GO:0006119 oxidative phosphorylation
2.43 1.21e-02 GO:0006260 DNA replication
2.88 1.26e-02 GO:0031398 positive regulation of protein ubiquitination
1.61 1.28e-02 GO:0015031 protein transport
2.61 1.29e-02 GO:0031396 regulation of protein ubiquitination
4.18 1.53e-02 GO:0042773 ATP synthesis coupled electron transport
4.18 1.53e-02 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.54 1.54e-02 GO:0006367 transcription initiation from RNA polymerase II promoter
3.54 1.54e-02 GO:0071158 positive regulation of cell cycle arrest
2.98 1.97e-02 GO:0043241 protein complex disassembly
2.98 1.97e-02 GO:0043624 cellular protein complex disassembly
3.06 2.24e-02 GO:0006364 rRNA processing
2.58 2.35e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.91 2.59e-02 GO:0032270 positive regulation of cellular protein metabolic process
2.69 2.62e-02 GO:0042254 ribosome biogenesis
2.33 2.69e-02 GO:0034470 ncRNA processing
2.03 2.75e-02 GO:0031401 positive regulation of protein modification process
2.50 2.82e-02 GO:0000226 microtubule cytoskeleton organization
1.94 2.84e-02 GO:0016568 chromatin modification
3.54 2.96e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
2.99 3.15e-02 GO:0006352 transcription initiation, DNA-dependent
3.33 3.53e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
3.07 3.56e-02 GO:0000236 mitotic prometaphase
2.57 3.72e-02 GO:0048193 Golgi vesicle transport
1.58 4.45e-02 GO:0033554 cellular response to stress

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 2.60e-58 GO:0044424 intracellular part
1.30 1.86e-55 GO:0005622 intracellular
1.40 1.01e-41 GO:0043227 membrane-bounded organelle
1.35 1.31e-41 GO:0043226 organelle
1.35 3.11e-41 GO:0043229 intracellular organelle
1.39 7.99e-41 GO:0043231 intracellular membrane-bounded organelle
1.41 6.30e-40 GO:0005737 cytoplasm
1.52 1.32e-33 GO:0044444 cytoplasmic part
1.54 1.31e-32 GO:0044422 organelle part
1.54 1.42e-32 GO:0044446 intracellular organelle part
1.96 1.35e-27 GO:0044428 nuclear part
1.69 5.78e-27 GO:0032991 macromolecular complex
1.89 3.89e-25 GO:0070013 intracellular organelle lumen
1.87 1.06e-24 GO:0031974 membrane-enclosed lumen
1.86 1.04e-23 GO:0043233 organelle lumen
3.01 3.56e-22 GO:0030529 ribonucleoprotein complex
1.92 8.02e-21 GO:0031981 nuclear lumen
1.42 1.81e-19 GO:0005634 nucleus
1.80 1.58e-18 GO:0005829 cytosol
1.97 7.90e-16 GO:0005654 nucleoplasm
1.88 3.13e-13 GO:0005739 mitochondrion
1.53 1.09e-12 GO:0043234 protein complex
1.56 1.39e-12 GO:0043228 non-membrane-bounded organelle
1.56 1.39e-12 GO:0043232 intracellular non-membrane-bounded organelle
1.08 6.44e-12 GO:0044464 cell part
1.08 6.73e-12 GO:0005623 cell
2.16 3.90e-11 GO:0031967 organelle envelope
2.12 1.22e-10 GO:0031975 envelope
3.70 3.65e-09 GO:0005681 spliceosomal complex
2.00 7.99e-08 GO:0044429 mitochondrial part
4.12 1.40e-06 GO:0071013 catalytic step 2 spliceosome
3.06 1.42e-05 GO:0000793 condensed chromosome
1.85 1.86e-05 GO:0015630 microtubule cytoskeleton
2.03 3.01e-05 GO:0005740 mitochondrial envelope
2.05 3.16e-05 GO:0031966 mitochondrial membrane
1.96 5.89e-05 GO:0005730 nucleolus
2.65 7.52e-05 GO:0005840 ribosome
3.90 8.70e-05 GO:0005643 nuclear pore
1.89 8.97e-05 GO:0005694 chromosome
3.68 1.19e-04 GO:0000779 condensed chromosome, centromeric region
3.74 1.81e-04 GO:0000777 condensed chromosome kinetochore
2.35 2.44e-04 GO:0005635 nuclear envelope
2.95 3.95e-04 GO:0044455 mitochondrial membrane part
3.41 4.39e-04 GO:0046930 pore complex
2.09 4.47e-04 GO:0019866 organelle inner membrane
2.53 4.77e-04 GO:0005819 spindle
2.14 5.23e-04 GO:0005743 mitochondrial inner membrane
1.37 1.17e-03 GO:0031090 organelle membrane
3.22 1.17e-03 GO:0000776 kinetochore
2.61 1.21e-03 GO:0044445 cytosolic part
5.66 1.70e-03 GO:0044452 nucleolar part
3.60 2.54e-03 GO:0000502 proteasome complex
3.43 4.84e-03 GO:0070469 respiratory chain
1.97 4.99e-03 GO:0005815 microtubule organizing center
3.25 5.60e-03 GO:0022626 cytosolic ribosome
2.20 5.67e-03 GO:0005813 centrosome
3.74 5.94e-03 GO:0015935 small ribosomal subunit
1.81 5.99e-03 GO:0044427 chromosomal part
1.63 6.47e-03 GO:0044451 nucleoplasm part
2.10 7.23e-03 GO:0005759 mitochondrial matrix
2.49 9.16e-03 GO:0000775 chromosome, centromeric region
2.13 1.41e-02 GO:0016604 nuclear body
7.72 1.91e-02 GO:0005732 small nucleolar ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.41 6.18e-30 GO:0005515 protein binding
1.17 5.82e-17 GO:0005488 binding
2.04 1.80e-10 GO:0003723 RNA binding
1.48 2.11e-07 GO:0000166 nucleotide binding
1.52 1.16e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.50 2.34e-06 GO:0017076 purine nucleotide binding
1.50 2.52e-06 GO:0032553 ribonucleotide binding
1.50 2.52e-06 GO:0032555 purine ribonucleotide binding
3.08 5.17e-06 GO:0003735 structural constituent of ribosome
1.52 5.65e-05 GO:0005524 ATP binding
1.50 8.90e-05 GO:0032559 adenyl ribonucleotide binding
1.50 1.26e-04 GO:0030554 adenyl nucleotide binding
2.88 2.11e-03 GO:0051082 unfolded protein binding
1.64 2.39e-03 GO:0016462 pyrophosphatase activity
1.63 2.81e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.20 3.26e-03 GO:0003824 catalytic activity
1.63 3.29e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.27 3.83e-03 GO:0003676 nucleic acid binding
9.44 5.10e-03 GO:0008139 nuclear localization sequence binding
5.79 5.48e-03 GO:0005048 signal sequence binding
1.62 5.99e-03 GO:0017111 nucleoside-triphosphatase activity
14.16 1.46e-02 GO:0030911 TPR domain binding
3.95 1.74e-02 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor