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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXN1

Z-value: 0.73

Motif logo

Transcription factors associated with FOXN1

Gene Symbol Gene ID Gene Info
ENSG00000109101.3 forkhead box N1

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_88323218 12.51 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr16_-_75498308 9.12 ENST00000569540.1
transmembrane protein 170A
chr16_-_75498553 8.26 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
transmembrane protein 170A
Uncharacterized protein
chr8_+_141521386 7.68 ENST00000220913.5
ENST00000519533.1
chromatin accessibility complex 1
chr15_+_99791567 7.28 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
leucine rich repeat containing 28
chr15_+_90777424 6.56 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr17_+_36508111 4.96 ENST00000331159.5
ENST00000577233.1
suppressor of cytokine signaling 7
chr2_-_28113217 4.74 ENST00000444339.2
ribokinase
chrX_+_153237740 4.22 ENST00000369982.4
transmembrane protein 187
chr17_-_64187973 4.04 ENST00000583358.1
ENST00000392769.2
centrosomal protein 112kDa
chr10_+_103113802 3.87 ENST00000370187.3
beta-transducin repeat containing E3 ubiquitin protein ligase
chr22_+_20104947 3.51 ENST00000402752.1
RAN binding protein 1
chr10_+_103113840 3.24 ENST00000393441.4
ENST00000408038.2
beta-transducin repeat containing E3 ubiquitin protein ligase
chr7_+_138916231 3.24 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr3_-_38691119 3.20 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
sodium channel, voltage-gated, type V, alpha subunit
chr11_+_1860200 3.01 ENST00000381911.1
troponin I type 2 (skeletal, fast)
chr22_+_29469100 2.98 ENST00000327813.5
ENST00000407188.1
kringle containing transmembrane protein 1
chr11_+_125774362 2.92 ENST00000530414.1
ENST00000530129.2
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr4_+_128651530 2.82 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr5_-_131892501 2.70 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr5_+_68389807 2.68 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
solute carrier family 30 (zinc transporter), member 5
chr11_+_125774258 2.67 ENST00000263576.6
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr12_-_52967600 2.64 ENST00000549343.1
ENST00000305620.2
keratin 74
chr19_+_49866851 2.60 ENST00000221498.2
ENST00000596402.1
dickkopf-like 1
chr11_+_65554493 2.57 ENST00000335987.3
ovo-like zinc finger 1
chr19_+_12902289 2.45 ENST00000302754.4
jun B proto-oncogene
chr17_+_7387919 2.42 ENST00000572844.1
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr18_+_9708162 2.39 ENST00000578921.1
RAB31, member RAS oncogene family
chr11_-_66360548 2.37 ENST00000333861.3
coiled-coil domain containing 87
chr15_+_92937144 2.35 ENST00000539113.1
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr17_-_64188177 2.34 ENST00000535342.2
centrosomal protein 112kDa
chrY_+_22737678 2.33 ENST00000382772.3
eukaryotic translation initiation factor 1A, Y-linked
chr14_+_77787227 2.22 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
glutathione S-transferase zeta 1
chr14_-_77787198 2.21 ENST00000261534.4
protein-O-mannosyltransferase 2
chr19_-_47164386 2.20 ENST00000391916.2
ENST00000410105.2
dishevelled-binding antagonist of beta-catenin 3
chr13_-_46961365 2.19 ENST00000417405.1
ENST00000378784.4
ENST00000534925.1
KIAA0226-like
chr21_+_17102311 2.16 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
ubiquitin specific peptidase 25
chr17_-_6915646 2.15 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chrX_-_83442915 2.14 ENST00000262752.2
ENST00000543399.1
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr10_-_125851961 2.14 ENST00000346248.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr3_+_47021168 2.10 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr20_+_3801162 2.10 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
adaptor-related protein complex 5, sigma 1 subunit
chr15_+_83776137 2.09 ENST00000322019.9
transmembrane 6 superfamily member 1
chr2_-_68694390 2.09 ENST00000377957.3
F-box protein 48
chr13_-_46961317 2.05 ENST00000322896.6
KIAA0226-like
chr2_+_241508039 2.03 ENST00000270357.4
arginyl aminopeptidase (aminopeptidase B)-like 1
chr3_+_14989186 1.97 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr5_+_154238149 1.96 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CCR4-NOT transcription complex, subunit 8
chr17_-_58469474 1.93 ENST00000300896.4
ubiquitin specific peptidase 32
chr13_-_46961580 1.90 ENST00000378787.3
ENST00000378797.2
ENST00000429979.1
ENST00000378781.3
KIAA0226-like
chr9_-_99381660 1.89 ENST00000375240.3
ENST00000463569.1
cell division cycle 14B
chr1_-_40237020 1.86 ENST00000327582.5
3-oxoacid CoA transferase 2
chr3_-_15469006 1.86 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
methyltransferase like 6
chr16_+_50187556 1.85 ENST00000561678.1
ENST00000357464.3
PAP associated domain containing 5
chr15_+_83776324 1.83 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
transmembrane 6 superfamily member 1
chr11_-_61684962 1.83 ENST00000394836.2
RAB3A interacting protein (rabin3)-like 1
chr14_+_37126765 1.80 ENST00000402703.2
paired box 9
chr19_+_48867652 1.79 ENST00000344846.2
synaptogyrin 4
chr15_+_92937058 1.78 ENST00000268164.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr15_-_78423567 1.74 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
calcium and integrin binding family member 2
chr17_-_40913029 1.73 ENST00000592195.1
ENST00000592670.1
ENST00000587694.1
ENST00000591082.1
RAMP2 antisense RNA 1
chr19_-_46296011 1.72 ENST00000377735.3
ENST00000270223.6
dystrophia myotonica, WD repeat containing
chr15_-_55700216 1.70 ENST00000569205.1
cell cycle progression 1
chr8_+_38243821 1.70 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr15_+_34261089 1.69 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr19_+_57742369 1.68 ENST00000415300.2
ENST00000448930.1
aurora kinase C
chr22_-_20104700 1.67 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr20_+_3827459 1.63 ENST00000416600.2
ENST00000428216.2
mitochondrial antiviral signaling protein
chr12_-_88535747 1.63 ENST00000309041.7
centrosomal protein 290kDa
chr8_-_98290087 1.61 ENST00000322128.3
TSPY-like 5
chr13_-_46626847 1.60 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chrX_+_16804544 1.59 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr4_+_3768075 1.59 ENST00000509482.1
ENST00000330055.5
adrenoceptor alpha 2C
chr10_+_127408110 1.55 ENST00000356792.4
erythroid differentiation regulatory factor 1
chr19_+_42772659 1.55 ENST00000572681.2
capicua transcriptional repressor
chr3_-_49158218 1.55 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
ubiquitin specific peptidase 19
chr20_+_4129496 1.54 ENST00000346595.2
spermine oxidase
chr17_-_33905521 1.54 ENST00000225873.4
peroxisomal biogenesis factor 12
chr11_-_32456891 1.52 ENST00000452863.3
Wilms tumor 1
chr15_-_55700522 1.52 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr11_+_117014983 1.52 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr17_-_40913275 1.51 ENST00000589716.1
ENST00000360166.3
RAMP2 antisense RNA 1
chr17_+_29421987 1.49 ENST00000431387.4
neurofibromin 1
chr5_-_140998481 1.49 ENST00000518047.1
diaphanous-related formin 1
chr18_+_9136758 1.46 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr19_-_46389359 1.46 ENST00000302165.3
interferon regulatory factor 2 binding protein 1
chr3_-_48936272 1.44 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chrX_-_71525742 1.43 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_-_150039249 1.43 ENST00000543571.1
large tumor suppressor kinase 1
chr1_+_183441500 1.42 ENST00000456731.2
SMG7 nonsense mediated mRNA decay factor
chr16_-_30022735 1.41 ENST00000564944.1
double C2-like domains, alpha
chr15_+_45422131 1.40 ENST00000321429.4
dual oxidase 1
chr1_-_25256368 1.39 ENST00000308873.6
runt-related transcription factor 3
chrX_+_15756382 1.39 ENST00000318636.3
carbonic anhydrase VB, mitochondrial
chr15_-_78423763 1.38 ENST00000557846.1
calcium and integrin binding family member 2
chr2_+_25264933 1.38 ENST00000401432.3
ENST00000403714.3
EFR3 homolog B (S. cerevisiae)
chr13_-_110438914 1.37 ENST00000375856.3
insulin receptor substrate 2
chr9_+_37667978 1.36 ENST00000539465.1
FERM and PDZ domain containing 1
chr16_+_1203194 1.36 ENST00000348261.5
ENST00000358590.4
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr1_-_46152174 1.35 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr1_+_235491714 1.33 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
geranylgeranyl diphosphate synthase 1
chr15_-_55700457 1.33 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr20_+_4129426 1.31 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
spermine oxidase
chr2_-_28113965 1.28 ENST00000302188.3
ribokinase
chr5_-_134871639 1.27 ENST00000314744.4
neurogenin 1
chr9_-_99775862 1.27 ENST00000602917.1
ENST00000375223.4
hippocampus abundant transcript-like 2
chr1_-_47697387 1.26 ENST00000371884.2
T-cell acute lymphocytic leukemia 1
chr9_+_34458771 1.26 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr13_-_95364389 1.25 ENST00000376945.2
SRY (sex determining region Y)-box 21
chr22_-_31741757 1.24 ENST00000215919.3
POZ (BTB) and AT hook containing zinc finger 1
chr14_+_70078303 1.22 ENST00000342745.4
KIAA0247
chr15_-_78423863 1.22 ENST00000539011.1
calcium and integrin binding family member 2
chr22_+_29469012 1.21 ENST00000400335.4
ENST00000400338.2
kringle containing transmembrane protein 1
chr20_-_56100155 1.20 ENST00000423479.3
ENST00000502686.2
ENST00000433949.3
ENST00000539382.1
ENST00000608903.1
CCCTC-binding factor (zinc finger protein)-like
chr6_+_126112001 1.19 ENST00000392477.2
nuclear receptor coactivator 7
chr15_+_45422178 1.17 ENST00000389037.3
ENST00000558322.1
dual oxidase 1
chr1_+_9294822 1.16 ENST00000377403.2
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chrX_-_106959631 1.16 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr2_-_110962544 1.15 ENST00000355301.4
ENST00000445609.2
ENST00000417665.1
ENST00000418527.1
ENST00000316534.4
ENST00000393272.3
nephronophthisis 1 (juvenile)
chr16_-_56459354 1.15 ENST00000290649.5
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr19_+_33463210 1.13 ENST00000590281.1
chromosome 19 open reading frame 40
chr15_+_71184931 1.13 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr5_-_140998616 1.12 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
diaphanous-related formin 1
chr10_+_13141441 1.12 ENST00000263036.5
optineurin
chr15_-_77712477 1.12 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr9_+_91933407 1.11 ENST00000375807.3
ENST00000339901.4
SECIS binding protein 2
chr19_+_19144384 1.11 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr1_+_24969755 1.11 ENST00000447431.2
ENST00000374389.4
serine/arginine repetitive matrix 1
chr17_-_8093471 1.09 ENST00000389017.4
chromosome 17 open reading frame 59
chr1_+_221054584 1.08 ENST00000549319.1
H2.0-like homeobox
chr5_+_110559784 1.08 ENST00000282356.4
calcium/calmodulin-dependent protein kinase IV
chr1_+_22778337 1.08 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr10_+_70715884 1.08 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr6_-_119670919 1.06 ENST00000368468.3
mannosidase, alpha, class 1A, member 1
chr3_+_50654550 1.02 ENST00000430409.1
ENST00000357955.2
mitogen-activated protein kinase-activated protein kinase 3
chr15_-_40213080 1.01 ENST00000561100.1
G protein-coupled receptor 176
chr5_+_131993856 1.00 ENST00000304506.3
interleukin 13
chr20_+_58515417 1.00 ENST00000360816.3
family with sequence similarity 217, member B
chr1_-_115300579 0.99 ENST00000358528.4
ENST00000525132.1
cold shock domain containing E1, RNA-binding
chr17_-_62207485 0.98 ENST00000433197.3
endoplasmic reticulum to nucleus signaling 1
chr5_+_110559603 0.97 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr12_+_49740700 0.95 ENST00000549441.2
ENST00000395069.3
DnaJ (Hsp40) homolog, subfamily C, member 22
chr3_+_137906154 0.93 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
armadillo repeat containing 8
chr2_-_31360887 0.92 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_+_11501816 0.91 ENST00000454412.2
dynein, axonemal, heavy chain 9
chr16_-_30022293 0.89 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
double C2-like domains, alpha
chr17_+_11501748 0.89 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr2_-_73520667 0.89 ENST00000545030.1
ENST00000436467.2
early growth response 4
chr7_-_120498357 0.89 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr19_-_38146289 0.89 ENST00000392144.1
ENST00000591444.1
ENST00000351218.2
ENST00000587809.1
ZFP30 zinc finger protein
chr12_-_88535842 0.88 ENST00000550962.1
ENST00000552810.1
centrosomal protein 290kDa
chr11_-_133826852 0.87 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr1_-_115300592 0.87 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
cold shock domain containing E1, RNA-binding
chr17_-_45266542 0.87 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
cell division cycle 27
chr21_+_44313375 0.87 ENST00000354250.2
ENST00000340344.4
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr17_-_43045439 0.86 ENST00000253407.3
complement component 1, q subcomponent-like 1
chr12_-_51663728 0.85 ENST00000603864.1
ENST00000605426.1
small cell adhesion glycoprotein
chr19_+_19030478 0.85 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr18_-_60985914 0.85 ENST00000589955.1
B-cell CLL/lymphoma 2
chr19_+_33463127 0.84 ENST00000589646.1
ENST00000588258.1
ENST00000590179.1
chromosome 19 open reading frame 40
chr10_+_13141585 0.83 ENST00000378764.2
optineurin
chr16_+_30662184 0.81 ENST00000300835.4
proline rich 14
chr11_-_82782861 0.80 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30, member RAS oncogene family
chr8_+_31496809 0.79 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chrX_-_153237258 0.79 ENST00000310441.7
host cell factor C1 (VP16-accessory protein)
chr5_+_154238096 0.78 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CCR4-NOT transcription complex, subunit 8
chr3_+_53528659 0.78 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr22_+_39916558 0.77 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr4_-_2758015 0.76 ENST00000510267.1
ENST00000503235.1
ENST00000315423.7
TNFAIP3 interacting protein 2
chr15_-_73076030 0.75 ENST00000311669.8
ADP-dependent glucokinase
chr2_-_54197915 0.75 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr12_+_56110315 0.74 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_+_45805342 0.74 ENST00000372090.5
target of EGR1, member 1 (nuclear)
chr19_-_663277 0.74 ENST00000292363.5
ring finger protein 126
chr17_+_40913264 0.73 ENST00000587142.1
ENST00000588576.1
receptor (G protein-coupled) activity modifying protein 2
chrY_+_4868267 0.72 ENST00000333703.4
protocadherin 11 Y-linked
chr12_+_56109926 0.72 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_153236819 0.71 ENST00000354233.3
host cell factor C1 (VP16-accessory protein)
chr5_+_154237778 0.70 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CCR4-NOT transcription complex, subunit 8
chr3_-_62358690 0.69 ENST00000475839.1
FEZ family zinc finger 2
chr19_-_11039261 0.69 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
Yip1 domain family, member 2
chr14_+_52456193 0.68 ENST00000261700.3
chromosome 14 open reading frame 166
chr7_-_92157747 0.68 ENST00000428214.1
ENST00000438045.1
peroxisomal biogenesis factor 1
chr1_+_74663896 0.68 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr12_+_51985001 0.67 ENST00000354534.6
sodium channel, voltage gated, type VIII, alpha subunit
chrX_+_91034260 0.67 ENST00000395337.2
protocadherin 11 X-linked
chr13_+_73356197 0.67 ENST00000326291.6
progesterone immunomodulatory binding factor 1
chr5_+_154238042 0.66 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CCR4-NOT transcription complex, subunit 8
chr1_-_217311090 0.63 ENST00000493603.1
ENST00000366940.2
estrogen-related receptor gamma
chr3_+_137906353 0.63 ENST00000461822.1
ENST00000485396.1
ENST00000471453.1
ENST00000470821.1
ENST00000471709.1
ENST00000538260.1
ENST00000393058.3
ENST00000463485.1
armadillo repeat containing 8
chr5_-_100238956 0.62 ENST00000231461.5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr13_-_73356009 0.62 ENST00000377780.4
ENST00000377767.4
DIS3 mitotic control homolog (S. cerevisiae)
chr10_-_105615164 0.62 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr15_+_71185148 0.62 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr12_+_70760056 0.61 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr17_-_42277203 0.59 ENST00000587097.1
ataxin 7-like 3
chr11_-_82782952 0.59 ENST00000534141.1
RAB30, member RAS oncogene family
chr17_+_3627185 0.58 ENST00000325418.4
germ cell associated 2 (haspin)
chr19_-_58662139 0.57 ENST00000598312.1
zinc finger protein 329
chr7_-_92157760 0.57 ENST00000248633.4
peroxisomal biogenesis factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0006014 D-ribose metabolic process(GO:0006014)
1.0 16.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
1.0 2.9 GO:0001172 transcription, RNA-templated(GO:0001172)
0.9 4.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.9 2.7 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.9 2.6 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.6 2.6 GO:0042335 cuticle development(GO:0042335)
0.6 1.9 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6 0.6 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6 1.8 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.6 4.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.6 4.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 2.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.5 3.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.5 2.9 GO:0046208 spermine catabolic process(GO:0046208)
0.5 2.8 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.4 2.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.4 1.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.4 1.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.4 2.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 1.6 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4 1.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.4 5.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 1.5 GO:0019046 release from viral latency(GO:0019046)
0.4 1.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 1.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 1.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3 1.6 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549) regulation of peroxisome organization(GO:1900063)
0.3 2.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 1.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 2.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.3 1.4 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.3 0.9 GO:0061743 motor learning(GO:0061743)
0.3 7.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 1.9 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 1.4 GO:0071105 response to interleukin-11(GO:0071105)
0.2 3.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 4.3 GO:0071318 cellular response to ATP(GO:0071318)
0.2 1.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.2 2.5 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.2 0.8 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 2.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.2 2.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 2.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 6.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 2.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.2 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 1.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.4 GO:2000344 cellular response to potassium ion(GO:0035865) positive regulation of acrosome reaction(GO:2000344)
0.2 1.5 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.7 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) negative regulation of natural killer cell activation(GO:0032815) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.2 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 5.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 1.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 7.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0032759 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.1 1.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.8 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 2.2 GO:0030220 platelet formation(GO:0030220)
0.1 0.3 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.8 GO:0003341 cilium movement(GO:0003341)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.2 GO:0035607 vacuolar phosphate transport(GO:0007037) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 2.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.8 GO:0060325 regulation of odontogenesis(GO:0042481) face morphogenesis(GO:0060325)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.6 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.4 GO:0051181 cofactor transport(GO:0051181)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 2.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.7 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 2.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 7.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.7 GO:0001510 RNA methylation(GO:0001510)
0.0 1.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.0 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 1.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.5 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0097503 glycosphingolipid biosynthetic process(GO:0006688) sialylation(GO:0097503)
0.0 1.0 GO:0048512 circadian behavior(GO:0048512)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.4 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 1.8 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 1.2 GO:0001942 hair follicle development(GO:0001942)
0.0 1.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 4.3 GO:0005927 muscle tendon junction(GO:0005927)
0.6 7.2 GO:0060077 inhibitory synapse(GO:0060077)
0.5 5.6 GO:0033391 chromatoid body(GO:0033391)
0.4 4.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 2.4 GO:0035976 AP1 complex(GO:0035976)
0.2 1.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 3.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.5 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 2.5 GO:0036038 MKS complex(GO:0036038)
0.2 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.3 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.9 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.8 GO:1990037 Lewy body core(GO:1990037)
0.1 3.0 GO:0005861 troponin complex(GO:0005861)
0.1 0.5 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 3.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 4.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 2.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 5.1 GO:0031514 motile cilium(GO:0031514)
0.0 5.9 GO:0001650 fibrillar center(GO:0001650)
0.0 22.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 2.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 1.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0043204 perikaryon(GO:0043204)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.0 2.9 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
1.0 2.9 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.9 2.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.7 5.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 2.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6 6.6 GO:0004645 phosphorylase activity(GO:0004645)
0.5 1.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.5 1.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.5 1.9 GO:0008410 CoA-transferase activity(GO:0008410)
0.5 1.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 2.6 GO:1990254 keratin filament binding(GO:1990254)
0.4 2.2 GO:0070097 delta-catenin binding(GO:0070097)
0.4 1.2 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.4 1.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 1.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.4 2.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 2.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 1.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 9.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 5.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.5 GO:0097643 amylin receptor activity(GO:0097643)
0.2 3.0 GO:0031014 troponin T binding(GO:0031014)
0.2 1.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 2.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 1.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 2.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 3.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 5.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 1.5 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 3.1 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.4 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 7.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 2.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 6.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.5 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364) cis-trans isomerase activity(GO:0016859)
0.0 0.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 2.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 5.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.8 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.5 GO:0005178 integrin binding(GO:0005178)
0.0 8.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 2.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 4.2 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 2.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 3.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 1.0 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response