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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TEAD4

Z-value: 1.28

Motif logo

Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
ENSG00000197905.4 TEA domain transcription factor 4

Activity-expression correlation:

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91539918 24.34 ENST00000548218.1
decorin
chr17_-_29624343 21.96 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr9_-_104249400 18.27 ENST00000374848.3
transmembrane protein 246
chr1_+_153004800 16.44 ENST00000392661.3
small proline-rich protein 1B
chr8_-_27115931 14.49 ENST00000523048.1
stathmin-like 4
chr19_+_35630022 14.07 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr7_-_37024665 14.03 ENST00000396040.2
engulfment and cell motility 1
chr5_+_173472607 13.91 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr12_+_79258547 13.51 ENST00000457153.2
synaptotagmin I
chr15_+_81475047 13.04 ENST00000559388.1
interleukin 16
chr12_+_79258444 12.75 ENST00000261205.4
synaptotagmin I
chr8_-_27115903 12.67 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr1_+_169079823 11.41 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_-_152489484 11.12 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr6_-_52705641 11.06 ENST00000370989.2
glutathione S-transferase alpha 5
chr2_+_238768187 11.02 ENST00000254661.4
ENST00000409726.1
receptor (G protein-coupled) activity modifying protein 1
chr17_-_66951474 10.74 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr19_+_35630628 10.68 ENST00000588715.1
ENST00000588607.1
FXYD domain containing ion transport regulator 1
chr15_-_22448819 10.66 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr12_-_91572278 10.32 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr6_-_109330702 10.13 ENST00000356644.7
sestrin 1
chr3_-_18466026 10.10 ENST00000417717.2
SATB homeobox 1
chr22_-_50523760 9.90 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_+_80733570 9.77 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr6_-_152958521 9.77 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
spectrin repeat containing, nuclear envelope 1
chr11_-_6440624 9.72 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_+_123813509 9.37 ENST00000460856.1
ENST00000240874.3
kalirin, RhoGEF kinase
chr17_+_47865917 8.66 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr19_+_19144384 8.50 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr2_-_179672142 8.50 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr2_+_90060377 8.47 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr7_+_147830776 8.45 ENST00000538075.1
contactin associated protein-like 2
chr9_+_71944241 7.94 ENST00000257515.8
family with sequence similarity 189, member A2
chrX_+_21392529 7.83 ENST00000425654.2
ENST00000543067.1
connector enhancer of kinase suppressor of Ras 2
chr10_-_50970322 7.80 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr19_-_19144243 7.66 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr16_+_30386098 7.66 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr22_-_50524298 7.54 ENST00000311597.5
megalencephalic leukoencephalopathy with subcortical cysts 1
chr20_+_1246908 7.31 ENST00000381873.3
ENST00000381867.1
syntaphilin
chr11_-_71639670 7.30 ENST00000533047.1
ENST00000529844.1
Putative short transient receptor potential channel 2-like protein
chr1_-_158656488 7.24 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr2_-_136875712 7.08 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr2_+_1418154 7.01 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr10_-_50970382 6.88 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr21_+_47878757 6.67 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr14_-_106622419 6.55 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr5_+_140261703 6.48 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr21_-_44299626 6.48 ENST00000330317.2
ENST00000398208.2
WD repeat domain 4
chr11_-_71639480 6.43 ENST00000529513.1
Putative short transient receptor potential channel 2-like protein
chr17_+_4855053 6.36 ENST00000518175.1
enolase 3 (beta, muscle)
chr1_+_160765947 6.31 ENST00000263285.6
ENST00000368039.2
lymphocyte antigen 9
chrX_+_21392553 6.25 ENST00000279451.4
connector enhancer of kinase suppressor of Ras 2
chr1_+_241695424 6.24 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_241695670 6.15 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_-_39033963 6.10 ENST00000381938.3
transmembrane protein 156
chr2_-_89459813 6.08 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr4_-_149365827 5.95 ENST00000344721.4
nuclear receptor subfamily 3, group C, member 2
chr7_+_87563557 5.90 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM metallopeptidase domain 22
chr9_-_15472730 5.65 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr14_-_107049312 5.60 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr1_+_66458072 5.58 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr20_+_43160458 5.53 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr10_-_62149433 5.47 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_70861647 5.45 ENST00000246895.4
ENST00000381060.2
statherin
chr1_+_163038565 5.44 ENST00000421743.2
regulator of G-protein signaling 4
chr4_+_71296204 5.32 ENST00000413702.1
mucin 7, secreted
chr4_-_186732048 5.32 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr1_-_207119738 5.26 ENST00000356495.4
polymeric immunoglobulin receptor
chr12_-_49393092 5.16 ENST00000421952.2
dendrin
chr15_-_20193370 5.15 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_128568721 5.14 ENST00000322313.4
ENST00000393006.1
ENST00000409658.3
ENST00000436787.1
WD repeat domain 33
chr3_+_138067666 5.07 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr14_-_106725723 5.01 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr1_-_154928562 4.90 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr3_+_189349162 4.77 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
tumor protein p63
chrX_+_22056165 4.73 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr12_+_109554386 4.72 ENST00000338432.7
acetyl-CoA carboxylase beta
chr2_-_196933536 4.69 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chr19_+_35630344 4.67 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr2_+_238767517 4.65 ENST00000404910.2
receptor (G protein-coupled) activity modifying protein 1
chr14_-_106518922 4.64 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr8_+_24151553 4.56 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr5_-_41261540 4.55 ENST00000263413.3
complement component 6
chr5_-_32313019 4.55 ENST00000280285.5
ENST00000264934.5
myotubularin related protein 12
chr8_+_42128812 4.48 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr5_+_180415839 4.33 ENST00000342868.6
butyrophilin-like 3
chr10_-_90712520 4.15 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr12_+_69201923 4.10 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr5_-_10308125 3.99 ENST00000296658.3
carboxymethylenebutenolidase homolog (Pseudomonas)
chr19_+_10541462 3.94 ENST00000293683.5
phosphodiesterase 4A, cAMP-specific
chr6_-_27835357 3.92 ENST00000331442.3
histone cluster 1, H1b
chr6_-_32634425 3.86 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
major histocompatibility complex, class II, DQ beta 1
chr5_-_138775177 3.78 ENST00000302060.5
DnaJ (Hsp40) homolog, subfamily C, member 18
chr11_+_49050504 3.76 ENST00000332682.7
tripartite motif containing 49B
chr1_-_60392452 3.76 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr19_+_57631411 3.75 ENST00000254181.4
ENST00000600940.1
ubiquitin specific peptidase 29
chr1_-_156252590 3.74 ENST00000361813.5
ENST00000368267.5
SMG5 nonsense mediated mRNA decay factor
chr2_-_211168332 3.72 ENST00000341685.4
myosin, light chain 1, alkali; skeletal, fast
chr14_-_106845789 3.69 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr6_+_153552455 3.68 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr13_+_113760098 3.56 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
coagulation factor VII (serum prothrombin conversion accelerator)
chr17_+_29664830 3.53 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr22_-_46450024 3.52 ENST00000396008.2
ENST00000333761.1
chromosome 22 open reading frame 26
chr12_+_69864129 3.51 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
fibroblast growth factor receptor substrate 2
chr10_+_32856764 3.51 ENST00000375030.2
ENST00000375028.3
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chrX_-_55024967 3.45 ENST00000545676.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chrX_-_33146477 3.41 ENST00000378677.2
dystrophin
chr12_-_111358372 3.37 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr10_-_75410771 3.34 ENST00000372873.4
synaptopodin 2-like
chr19_+_9296279 3.29 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr2_-_89513402 3.28 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr7_-_116963334 3.27 ENST00000265441.3
wingless-type MMTV integration site family member 2
chr1_+_1215816 3.20 ENST00000379116.5
sodium channel, non-voltage-gated 1, delta subunit
chr2_-_211341411 3.19 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr14_+_68286516 3.16 ENST00000471583.1
ENST00000487270.1
ENST00000488612.1
RAD51 paralog B
chr2_-_161056802 3.06 ENST00000283249.2
ENST00000409872.1
integrin, beta 6
chr8_-_70745575 3.04 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr16_-_20681177 3.04 ENST00000524149.1
acyl-CoA synthetase medium-chain family member 1
chr20_+_33814457 3.01 ENST00000246186.6
matrix metallopeptidase 24 (membrane-inserted)
chr19_+_54369608 2.96 ENST00000336967.3
myeloid-associated differentiation marker
chr4_-_47983519 2.96 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr4_+_87928413 2.93 ENST00000544085.1
AF4/FMR2 family, member 1
chr12_+_10460417 2.89 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr8_+_55370487 2.87 ENST00000297316.4
SRY (sex determining region Y)-box 17
chr19_+_52074502 2.87 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
zinc finger protein 175
chr3_+_101546827 2.84 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr4_+_96012614 2.83 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr19_-_3786354 2.80 ENST00000395040.2
ENST00000310132.6
megakaryocyte-associated tyrosine kinase
chr17_+_44588877 2.72 ENST00000576629.1
leucine rich repeat containing 37, member A2
chr1_+_16010779 2.72 ENST00000375799.3
ENST00000375793.2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr16_+_33006369 2.70 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr11_-_59633951 2.70 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr11_+_60223312 2.66 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr11_+_62009653 2.65 ENST00000244926.3
secretoglobin, family 1D, member 2
chr1_-_79472365 2.64 ENST00000370742.3
EGF, latrophilin and seven transmembrane domain containing 1
chr4_+_41614909 2.64 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr2_+_38893047 2.61 ENST00000272252.5
galactose mutarotase (aldose 1-epimerase)
chr13_+_49280951 2.61 ENST00000282018.3
cysteinyl leukotriene receptor 2
chr6_+_122720681 2.58 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr1_+_171283331 2.48 ENST00000367749.3
flavin containing monooxygenase 4
chr11_+_55029628 2.41 ENST00000417545.2
tripartite motif containing 48
chr19_-_3786253 2.38 ENST00000585778.1
megakaryocyte-associated tyrosine kinase
chr10_-_735553 2.37 ENST00000280886.6
ENST00000423550.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr11_+_60223225 2.27 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr7_+_152456829 2.27 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr1_+_32716840 2.27 ENST00000336890.5
lymphocyte-specific protein tyrosine kinase
chrX_+_37639264 2.26 ENST00000378588.4
cytochrome b-245, beta polypeptide
chr1_+_164528866 2.23 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr4_-_186317034 2.21 ENST00000505916.1
LRP2 binding protein
chr2_-_161056762 2.16 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr1_-_175162048 2.14 ENST00000444639.1
KIAA0040
chr11_-_79151695 2.13 ENST00000278550.7
teneurin transmembrane protein 4
chr8_+_24151620 2.12 ENST00000437154.2
ADAM metallopeptidase domain 28
chr6_+_25754927 2.11 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr2_+_157330081 2.10 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr17_+_38219063 2.09 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha
chr3_+_123813543 2.05 ENST00000360013.3
kalirin, RhoGEF kinase
chr1_+_32716857 2.01 ENST00000482949.1
ENST00000495610.2
lymphocyte-specific protein tyrosine kinase
chr9_-_104145795 1.99 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr12_+_32260085 1.98 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
bicaudal D homolog 1 (Drosophila)
chr11_-_10590118 1.98 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_46679144 1.80 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr21_-_27423339 1.79 ENST00000415997.1
amyloid beta (A4) precursor protein
chrX_+_37639302 1.79 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr10_+_5005445 1.73 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr3_-_164875850 1.71 ENST00000472120.1
RP11-747D18.1
chr19_+_17862274 1.68 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCH domain only 1
chr19_-_41256207 1.68 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr4_-_110723335 1.68 ENST00000394634.2
complement factor I
chr13_-_46679185 1.66 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr13_-_99910673 1.63 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr14_+_78870030 1.63 ENST00000553631.1
ENST00000554719.1
neurexin 3
chr13_+_24553933 1.62 ENST00000424834.2
ENST00000439928.2
spermatogenesis associated 13
RP11-309I15.1
chr4_+_71588372 1.62 ENST00000536664.1
RUN and FYVE domain containing 3
chr10_+_123923205 1.59 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr1_+_160051319 1.57 ENST00000368088.3
potassium inwardly-rectifying channel, subfamily J, member 9
chr5_-_150603679 1.56 ENST00000355417.2
coiled-coil domain containing 69
chr1_+_244214577 1.54 ENST00000358704.4
zinc finger and BTB domain containing 18
chr17_+_32582293 1.46 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr4_+_120056939 1.45 ENST00000307128.5
myozenin 2
chr5_+_53751445 1.44 ENST00000302005.1
heat shock 27kDa protein 3
chr4_+_55095264 1.41 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_86268065 1.41 ENST00000551529.1
ENST00000256010.6
neurotensin
chr12_+_10460549 1.39 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr6_-_42690312 1.38 ENST00000230381.5
peripherin 2 (retinal degeneration, slow)
chr4_-_110723194 1.36 ENST00000394635.3
complement factor I
chr19_-_51466681 1.34 ENST00000456750.2
kallikrein-related peptidase 6
chr8_+_50824233 1.31 ENST00000522124.1
syntrophin, gamma 1
chr4_+_40337340 1.26 ENST00000310169.2
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr9_-_33402506 1.26 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
aquaporin 7
chr2_-_235405679 1.24 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr4_-_110723134 1.24 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_155511887 1.23 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr11_-_63376013 1.19 ENST00000540943.1
phospholipase A2, group XVI
chr15_+_100106126 1.18 ENST00000558812.1
ENST00000338042.6
myocyte enhancer factor 2A
chr1_-_151798546 1.18 ENST00000356728.6
RAR-related orphan receptor C
chrX_-_15402498 1.15 ENST00000297904.3
c-fos induced growth factor (vascular endothelial growth factor D)
chr11_-_102595681 1.10 ENST00000236826.3
matrix metallopeptidase 8 (neutrophil collagenase)
chr2_-_233641265 1.07 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr11_-_10590238 1.04 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 26.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.9 29.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
3.2 9.7 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.9 34.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.9 11.4 GO:1903276 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
2.8 8.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
2.8 8.4 GO:0071109 superior temporal gyrus development(GO:0071109)
2.5 12.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.3 11.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
2.2 8.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
2.1 20.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.7 15.7 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.4 5.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.4 4.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.3 10.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.2 4.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.2 3.6 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
1.2 4.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.2 3.5 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
1.2 3.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.2 17.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.1 4.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.1 4.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.1 5.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.0 3.0 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.0 7.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.0 2.9 GO:0060214 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) endocardium formation(GO:0060214) gall bladder development(GO:0061010)
0.9 4.7 GO:1904383 response to sodium phosphate(GO:1904383)
0.9 9.0 GO:0042908 xenobiotic transport(GO:0042908)
0.9 2.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.9 3.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.8 4.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.7 3.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.7 11.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.7 2.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.7 1.4 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.7 2.1 GO:0045925 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.7 4.1 GO:0090131 mesenchyme migration(GO:0090131)
0.7 3.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.7 3.3 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.6 5.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.6 13.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.6 2.8 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.5 2.7 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.5 3.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 7.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.5 5.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.5 15.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 5.5 GO:0046541 saliva secretion(GO:0046541)
0.5 1.5 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5 20.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 5.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 18.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.4 2.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 3.9 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 4.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.4 3.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 2.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 28.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 2.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.4 14.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 1.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.3 5.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 6.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.3 16.4 GO:0018149 peptide cross-linking(GO:0018149)
0.3 1.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 3.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 2.7 GO:0015889 cobalamin transport(GO:0015889)
0.3 1.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 8.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.3 23.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.3 1.3 GO:0015793 glycerol transport(GO:0015793)
0.2 1.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 2.0 GO:0019530 taurine metabolic process(GO:0019530)
0.2 3.8 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 1.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 1.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 5.9 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 7.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 2.7 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.2 2.5 GO:0042737 drug catabolic process(GO:0042737)
0.2 1.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 5.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 17.3 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.2 5.1 GO:0006379 mRNA cleavage(GO:0006379)
0.1 6.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 5.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 11.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 3.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.2 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 1.4 GO:0050880 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.1 0.9 GO:0030578 PML body organization(GO:0030578)
0.1 3.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 13.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 6.5 GO:0006400 tRNA modification(GO:0006400)
0.1 5.3 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 1.6 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 1.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 13.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 4.5 GO:1901998 toxin transport(GO:1901998)
0.1 3.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.9 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 1.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.2 GO:0006954 inflammatory response(GO:0006954)
0.1 3.7 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.1 3.2 GO:0050909 sensory perception of taste(GO:0050909)
0.1 5.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 4.9 GO:0042100 B cell proliferation(GO:0042100)
0.1 4.3 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.6 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 0.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 2.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.6 GO:0021987 cerebral cortex development(GO:0021987)
0.0 3.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 5.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 1.4 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 6.0 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 3.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.8 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.9 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 2.9 GO:0051607 defense response to virus(GO:0051607)
0.0 1.4 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 26.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.5 34.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.2 15.7 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
2.1 14.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.0 40.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.8 5.3 GO:0097679 other organism cytoplasm(GO:0097679)
1.7 5.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.6 20.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.4 10.1 GO:0061700 GATOR2 complex(GO:0061700)
1.3 6.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.3 11.5 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.2 14.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.1 6.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.0 4.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.0 7.2 GO:0032437 cuticular plate(GO:0032437)
0.7 8.4 GO:0033010 paranodal junction(GO:0033010)
0.7 33.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.7 2.0 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.6 13.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 3.2 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 4.7 GO:0016013 syntrophin complex(GO:0016013)
0.5 4.5 GO:0005579 membrane attack complex(GO:0005579)
0.5 16.7 GO:0005859 muscle myosin complex(GO:0005859)
0.4 5.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 2.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 4.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 5.4 GO:0043194 axon initial segment(GO:0043194)
0.3 4.7 GO:0005858 axonemal dynein complex(GO:0005858)
0.3 16.4 GO:0001533 cornified envelope(GO:0001533)
0.3 3.3 GO:1990909 Wnt signalosome(GO:1990909)
0.3 4.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 4.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 5.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 3.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 5.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.3 GO:0000242 pericentriolar material(GO:0000242)
0.2 5.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 3.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 3.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 16.8 GO:0005901 caveola(GO:0005901)
0.1 28.8 GO:0030426 growth cone(GO:0030426)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 15.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 21.0 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 10.0 GO:0030018 Z disc(GO:0030018)
0.1 3.9 GO:0000786 nucleosome(GO:0000786)
0.1 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:0051233 spindle midzone(GO:0051233)
0.1 4.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 12.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 7.6 GO:0072562 blood microparticle(GO:0072562)
0.0 3.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 34.0 GO:0009986 cell surface(GO:0009986)
0.0 3.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 6.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.1 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 2.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 7.3 GO:0030424 axon(GO:0030424)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.0 GO:0043235 receptor complex(GO:0043235)
0.0 6.8 GO:0016607 nuclear speck(GO:0016607)
0.0 3.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.7 GO:0010008 endosome membrane(GO:0010008)
0.0 1.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.6 GO:0098793 presynapse(GO:0098793)
0.0 3.5 GO:0044445 cytosolic part(GO:0044445)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 26.3 GO:0030348 syntaxin-3 binding(GO:0030348)
3.9 15.7 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
2.9 14.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.0 10.1 GO:0070728 leucine binding(GO:0070728)
1.8 5.5 GO:0046848 hydroxyapatite binding(GO:0046848)
1.5 13.9 GO:0032051 clathrin light chain binding(GO:0032051)
1.4 4.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.2 4.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.2 7.0 GO:0004447 iodide peroxidase activity(GO:0004447)
1.1 9.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.1 4.5 GO:0008384 IkappaB kinase activity(GO:0008384)
1.1 6.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.0 10.0 GO:0031433 telethonin binding(GO:0031433)
0.9 4.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.8 12.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.8 17.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.7 20.9 GO:0005521 lamin binding(GO:0005521)
0.7 11.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 9.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.7 3.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.7 5.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.6 7.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 3.2 GO:0043295 glutathione binding(GO:0043295)
0.6 33.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 13.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 6.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.5 2.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 2.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.5 9.7 GO:0048156 tau protein binding(GO:0048156)
0.5 26.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 8.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 2.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.5 5.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.5 1.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 34.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 1.7 GO:0047023 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4 4.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 3.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 3.0 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 2.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 3.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 1.3 GO:0015254 glycerol channel activity(GO:0015254)
0.3 2.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 4.0 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.3 3.2 GO:0000150 recombinase activity(GO:0000150)
0.3 5.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 2.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 4.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein intermediate chain binding(GO:0045505)
0.3 3.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 3.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 2.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 9.5 GO:0030552 cAMP binding(GO:0030552)
0.3 6.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.7 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 3.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 3.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 11.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 2.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 4.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 3.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 3.8 GO:0070330 aromatase activity(GO:0070330)
0.2 5.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 27.0 GO:0003823 antigen binding(GO:0003823)
0.2 2.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 1.8 GO:0051425 PTB domain binding(GO:0051425)
0.2 5.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.2 3.3 GO:0048018 receptor agonist activity(GO:0048018)
0.1 3.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 17.4 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 15.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 5.5 GO:0030507 spectrin binding(GO:0030507)
0.1 3.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 8.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 6.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 10.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 21.6 GO:0015631 tubulin binding(GO:0015631)
0.1 7.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 5.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 6.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 9.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.5 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 6.2 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 33.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 26.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 11.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 8.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 3.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 14.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 4.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 8.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 23.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 5.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 6.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 10.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 7.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 6.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 5.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 7.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 5.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 4.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 11.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 8.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 4.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.4 7.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.3 34.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 12.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 5.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 18.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4 4.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 12.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 11.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 11.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 7.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 10.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 5.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 30.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 2.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 4.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 3.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 20.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 3.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 9.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 8.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 18.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 5.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 4.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 3.5 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.1 10.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 8.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 5.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 9.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 2.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 1.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 3.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 2.1 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)