Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UAAGACG
Z-value: 0.32
Motif logo
miRNA associated with seed UAAGACG
Top targets:  
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_43328004 Show fit | 2.88 |
ENST00000454177.1
ENST00000429705.2 ENST00000296088.7 ENST00000437827.1 |
SNF related kinase |
|
| chr3_-_18466787 Show fit | 2.84 |
ENST00000338745.6
ENST00000450898.1 |
SATB homeobox 1 |
|
| chr6_-_99797522 Show fit | 2.76 |
ENST00000389677.5
|
failed axon connections homolog (Drosophila) |
|
| chr8_+_56014949 Show fit | 2.52 |
ENST00000327381.6
|
XK, Kell blood group complex subunit-related family, member 4 |
|
| chr10_+_11206925 Show fit | 2.49 |
ENST00000354440.2
ENST00000315874.4 ENST00000427450.1 |
CUGBP, Elav-like family member 2 |
|
| chr2_+_120517174 Show fit | 2.24 |
ENST00000263708.2
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
|
| chr8_+_38614807 Show fit | 1.78 |
ENST00000330691.6
ENST00000348567.4 |
transforming, acidic coiled-coil containing protein 1 |
|
| chr12_-_92539614 Show fit | 1.69 |
ENST00000256015.3
|
B-cell translocation gene 1, anti-proliferative |
|
| chr1_-_108507631 Show fit | 1.68 |
ENST00000527011.1
ENST00000370056.4 |
vav 3 guanine nucleotide exchange factor |
|
| chr13_-_107220455 Show fit | 1.65 |
ENST00000400198.3
|
arginine and glutamate rich 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UAAGACG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.8 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 2.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 2.2 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 1.7 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 1.7 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.5 | 1.6 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.0 | 1.5 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.4 | 1.4 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.3 | 1.4 | GO:0035910 | N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.0 | 1.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.2 | 1.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 1.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.2 | 1.1 | GO:0001740 | Barr body(GO:0001740) |
| 0.1 | 1.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 1.0 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.0 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 1.0 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 2.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.2 | 2.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 2.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 1.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 1.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 1.4 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 1.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 1.2 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.1 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 1.7 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 1.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.2 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 1.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.6 | PID P53 REGULATION PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 2.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.7 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.6 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 1.1 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.1 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.6 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |