Motif ID: AACACUG

Z-value: 2.000


Mature miRNA associated with seed AACACUG:

NamemiRBase Accession
hsa-miR-141 MIMAT0000432
hsa-miR-200a MIMAT0000682



Activity profile for motif AACACUG.

activity profile for motif AACACUG


Sorted Z-values histogram for motif AACACUG

Sorted Z-values for motif AACACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AACACUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_61542928 6.958 NM_001145511
NFIA
nuclear factor I/A
chr1_+_61547625 6.637 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61547388 6.224 NM_001145512
NFIA
nuclear factor I/A
chr4_-_186697065 6.133 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr10_-_81205091 6.038 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_-_186733372 6.032 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr4_-_186732047 5.928 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186732208 5.805 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186877869 5.686 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr1_+_84630575 5.681 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_+_84609941 5.635 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_84630014 5.572 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr17_-_8534008 5.347 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr1_+_84647342 5.230 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_112631552 4.842 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr4_+_41362750 4.826 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr6_+_11538486 4.773 NM_001100829
TMEM170B
transmembrane protein 170B
chr7_+_12726413 4.649 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr4_+_41614911 4.644 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr6_-_16761600 4.544 NM_000332
NM_001128164
ATXN1

ataxin 1

chr7_+_12726910 4.520 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chr13_-_77460432 4.485 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr9_-_10612722 4.285 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr9_-_8733893 4.142 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr2_+_191745546 3.941 NM_014905
GLS
glutaminase
chr4_-_186578122 3.916 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr6_-_84419108 3.819 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr8_-_127570710 3.737 NM_174911
FAM84B
family with sequence similarity 84, member B
chr9_+_127054246 3.697 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr6_-_84418705 3.671 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr2_-_240322620 3.638 NM_006037
HDAC4
histone deacetylase 4
chr1_+_25943958 3.589 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr3_+_39851028 3.562 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr4_-_42658883 3.560 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr9_+_127054567 3.532 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr21_+_18885104 3.516 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr3_+_25469833 3.512 NM_000965
RARB
retinoic acid receptor, beta
chr3_-_149375584 3.308 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr3_-_149421059 3.162 NM_001168278
WWTR1
WW domain containing transcription regulator 1
chr3_+_43328001 3.077 NM_001100594
NM_017719
SNRK

SNF related kinase

chr13_+_32605436 3.061 NM_023037
FRY
furry homolog (Drosophila)
chr17_+_68165660 3.047 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_-_86094792 3.022 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_+_127019782 2.981 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr13_-_110438896 2.935 NM_003749
IRS2
insulin receptor substrate 2
chr9_+_127020462 2.869 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr11_+_86748870 2.836 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr14_-_89883306 2.822 NM_005197
FOXN3
forkhead box N3
chr4_+_144257982 2.783 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr7_-_132261268 2.707 NM_001105543
NM_020911
PLXNA4

plexin A4

chr12_-_29937691 2.660 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr12_-_29936685 2.641 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_+_178694273 2.599 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr11_-_2162340 2.576 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_86116016 2.563 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_+_33563772 2.455 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr8_-_4852262 2.436 NM_033225
CSMD1
CUB and Sushi multiple domains 1
chr6_+_107811272 2.377 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr11_-_2170792 2.374 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_90085325 2.333 NM_001085471
FOXN3
forkhead box N3
chr11_+_134094545 2.322 NM_052875
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr2_+_45878912 2.270 NM_005400
PRKCE
protein kinase C, epsilon
chr11_-_2160199 2.225 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_17282931 2.186 NM_153020
RBM24
RNA binding motif protein 24
chr20_-_23030141 2.169 NM_000361
THBD
thrombomodulin
chr4_+_126237566 2.147 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr9_-_14693459 2.133 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr9_+_90112754 2.075 NM_004938
DAPK1
death-associated protein kinase 1
chr22_-_29075708 2.062 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr9_-_124984018 2.051 NM_001242335
LHX6
LIM homeobox 6
chr13_+_80055257 2.047 NM_001161407
NM_019080
NDFIP2

Nedd4 family interacting protein 2

chr12_-_95044205 1.997 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr1_+_93913566 1.980 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like


chr6_+_1610680 1.947 NM_001453
FOXC1
forkhead box C1
chr12_-_42877785 1.927 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr12_-_42877413 1.898 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr6_+_17282294 1.872 NM_001143941
RBM24
RNA binding motif protein 24
chr6_+_17281773 1.853 NM_001143942
RBM24
RNA binding motif protein 24
chr12_-_42983412 1.851 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_46766563 1.849 NM_018976
SLC38A2
solute carrier family 38, member 2
chr17_-_37557851 1.823 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr10_-_64578926 1.822 NM_001136178
EGR2
early growth response 2
chr9_+_115513050 1.817 NM_001012994
SNX30
sorting nexin family member 30
chr9_-_124990706 1.811 NM_001242333
LHX6
LIM homeobox 6
chr15_-_56035176 1.798 NM_173814
PRTG
protogenin
chr4_-_101439071 1.786 NM_001159694
NM_016242
EMCN

endomucin

chr10_-_33623771 1.782 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr3_-_18466759 1.725 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr10_-_64576123 1.724 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr2_+_179184970 1.721 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr3_-_18480203 1.717 NM_001131010
SATB1
SATB homeobox 1
chr2_+_179059071 1.702 NM_001201480
NM_001201481
NM_001201482
NM_032523
OSBPL6



oxysterol binding protein-like 6



chr1_+_24742244 1.699 NM_020448
NIPAL3
NIPA-like domain containing 3
chr11_-_67888857 1.699 NM_001277
NM_212469
CHKA

choline kinase alpha

chr2_+_70485204 1.696 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr2_+_61292999 1.683 NM_001129993
KIAA1841
KIAA1841
chr9_-_98270321 1.681 NM_001083604
NM_001083605
PTCH1

patched 1

chr21_-_40033617 1.668 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr6_-_13408368 1.659 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr7_+_114562140 1.656 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr9_-_98269480 1.655 NM_001083607
PTCH1
patched 1
chr2_-_188312872 1.649 NM_005795
CALCRL
calcitonin receptor-like
chr7_+_150690838 1.649 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr21_-_39870303 1.648 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr1_-_33168356 1.645 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr4_+_87928083 1.639 NM_005935
AFF1
AF4/FMR2 family, member 1
chr1_+_84764048 1.639 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr14_-_30396811 1.630 NM_002742
PRKD1
protein kinase D1
chr1_+_84768333 1.615 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr3_-_52479042 1.611 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr17_+_61699786 1.608 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr1_+_84767288 1.596 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr6_+_32121228 1.573 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr9_-_124990949 1.554 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr15_+_57210823 1.518 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr9_-_98270830 1.504 NM_000264
PTCH1
patched 1
chr2_+_178257371 1.501 NM_003659
AGPS
alkylglycerone phosphate synthase
chr13_-_74707913 1.501 NM_007249
KLF12
Kruppel-like factor 12
chr14_+_53019865 1.486 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr4_-_85887543 1.470 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr1_-_154474524 1.466 NM_001010846
SHE
Src homology 2 domain containing E
chr6_+_17600504 1.451 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr6_-_52441815 1.447 NM_012288
TRAM2
translocation associated membrane protein 2
chr12_-_56615679 1.446 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr1_+_82266081 1.432 NM_012302
LPHN2
latrophilin 2
chr5_+_95066628 1.415 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr8_+_97505876 1.413 NM_002998
SDC2
syndecan 2
chr12_-_56615484 1.409 NM_001242826
RNF41
ring finger protein 41
chr19_-_31840118 1.408 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr2_+_203241044 1.406 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr3_-_141719188 1.403 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_17338182 1.389 NM_001621
AHR
aryl hydrocarbon receptor
chr10_-_126849556 1.382 NM_001083914
CTBP2
C-terminal binding protein 2
chr3_+_32148000 1.369 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr5_+_153570270 1.366 NM_198321
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr18_+_8717368 1.356 NM_015210
CCDC165
coiled-coil domain containing 165
chr9_-_79520878 1.344 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr1_+_52082545 1.339 NM_024586
NM_148906
NM_148908
NM_148909
OSBPL9



oxysterol binding protein-like 9



chr1_+_52195458 1.337 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr7_-_105319608 1.333 NM_138495
ATXN7L1
ataxin 7-like 1
chr12_+_27397077 1.331 NM_015000
STK38L
serine/threonine kinase 38 like
chr11_+_92085261 1.325 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr6_-_35696359 1.290 NM_001145775
FKBP5
FK506 binding protein 5
chr1_-_225616556 1.283 NM_194442
LBR
lamin B receptor
chr15_+_57511616 1.276 NM_207040
TCF12
transcription factor 12
chr3_-_149051258 1.275 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chrX_+_13671224 1.263 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr18_+_13611664 1.257 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr3_-_17741511 1.255 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr20_-_23066828 1.246 NM_012072
CD93
CD93 molecule
chr6_+_32121775 1.226 NM_001204103
NM_005155
PPT2-EGFL8
PPT2

PPT2-EGFL8 readthrough
palmitoyl-protein thioesterase 2

chr6_+_116832807 1.214 NM_153711
FAM26E
family with sequence similarity 26, member E
chr15_+_63569748 1.212 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chrX_+_21857655 1.196 NM_015884
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr7_-_11871735 1.185 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr17_-_49337370 1.172 NM_017643
MBTD1
mbt domain containing 1
chr10_-_126716452 1.171 NM_022802
CTBP2
C-terminal binding protein 2
chr12_+_50898744 1.169 NM_173602
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr11_-_63536112 1.168 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr18_+_13620866 1.165 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr9_+_5450455 1.142 NM_014143
CD274
CD274 molecule
chr1_-_179112178 1.140 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr8_-_38326351 1.140 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr4_+_87856152 1.138 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr9_-_16870719 1.133 NM_017637
BNC2
basonuclin 2
chr18_-_53255734 1.129 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr1_+_114522029 1.128 NM_020190
OLFML3
olfactomedin-like 3
chr8_-_81787015 1.124 NM_001033723
ZNF704
zinc finger protein 704
chr9_+_131644780 1.121 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr1_+_84543629 1.108 NM_002731
NM_207578
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr11_+_117049838 1.105 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr4_+_55523906 1.098 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr8_-_38325241 1.097 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr5_-_111093251 1.093 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr3_-_17782398 1.088 NM_014744
TBC1D5
TBC1 domain family, member 5
chr10_-_126849066 1.083 NM_001329
CTBP2
C-terminal binding protein 2
chrX_-_119709618 1.077 NM_003588
CUL4B
cullin 4B
chr19_-_48752921 1.074 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr18_+_59992519 1.070 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr10_+_65281108 1.067 NM_001001330
REEP3
receptor accessory protein 3
chr3_-_64211111 1.067 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_-_35077652 1.064 NM_015283
DPY19L1
dpy-19-like 1 (C. elegans)
chr10_+_102106771 1.063 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_36584692 1.060 NM_001199417
ARHGAP23
Rho GTPase activating protein 23
chr5_-_88179278 1.058 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_-_48744276 1.053 NM_001184900
CARD8
caspase recruitment domain family, member 8
chr4_-_129209983 1.052 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr17_-_74137370 1.051 NM_001454
FOXJ1
forkhead box J1
chr12_+_12938540 1.051 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr7_+_100136784 1.050 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr1_-_225840660 1.048 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr8_-_17555158 1.048 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_-_111093030 1.045 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr3_-_56502364 1.035 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr11_+_74459900 1.031 NM_001098638
RNF169
ring finger protein 169
chr11_+_134123406 1.030 NM_014384
ACAD8
acyl-CoA dehydrogenase family, member 8
chr9_+_131644368 1.023 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr3_-_17784096 1.018 NM_001134380
TBC1D5
TBC1 domain family, member 5
chr1_-_92371558 1.011 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr1_+_109102970 1.000 NM_001010883
FAM102B
family with sequence similarity 102, member B

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 9.88e-05 GO:0044464 cell part
1.06 1.02e-04 GO:0005623 cell
1.10 2.37e-04 GO:0005622 intracellular
1.13 8.14e-04 GO:0043231 intracellular membrane-bounded organelle
1.10 9.62e-04 GO:0044424 intracellular part
1.13 9.92e-04 GO:0043227 membrane-bounded organelle
1.10 2.01e-02 GO:0043229 intracellular organelle
1.10 2.71e-02 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.15e-03 GO:0046872 metal ion binding
1.24 1.29e-03 GO:0043167 ion binding
1.24 1.88e-03 GO:0043169 cation binding
1.08 1.74e-02 GO:0005488 binding