Motif ID: AAGGUGC

Z-value: 0.565


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
hsa-miR-18a MIMAT0000072
hsa-miR-18b MIMAT0001412
hsa-miR-4735-3p MIMAT0019861



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_56110899 0.813 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr4_-_186733372 0.790 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr6_-_11382501 0.780 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr4_-_186877869 0.759 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186697065 0.757 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186732208 0.750 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186732047 0.743 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr1_-_95007139 0.641 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr2_+_12856813 0.630 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr6_+_138188352 0.600 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_186578122 0.518 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr20_+_34700257 0.480 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_34742656 0.479 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_132805456 0.447 NM_015033
FNBP1
formin binding protein 1
chr12_+_11802726 0.388 NM_001987
ETV6
ets variant 6
chr11_+_109964086 0.379 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr8_-_81787015 0.368 NM_001033723
ZNF704
zinc finger protein 704
chr9_-_74383301 0.328 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr10_-_81205091 0.327 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr6_-_16761600 0.325 NM_000332
NM_001128164
ATXN1

ataxin 1

chr15_-_60919642 0.298 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr3_-_64211111 0.289 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr2_+_28615771 0.281 NM_005253
FOSL2
FOS-like antigen 2
chr6_-_111136407 0.268 NM_015076
CDK19
cyclin-dependent kinase 19
chr3_+_37903643 0.267 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr6_-_11232901 0.267 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr15_-_61521478 0.266 NM_134261
RORA
RAR-related orphan receptor A
chr6_+_39760772 0.229 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr3_+_105085553 0.225 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr6_+_39760148 0.212 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr3_+_107241782 0.208 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr5_+_31799030 0.198 NM_178140
PDZD2
PDZ domain containing 2
chr15_-_60884615 0.191 NM_134262
RORA
RAR-related orphan receptor A
chr6_-_143266283 0.189 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr15_-_34630203 0.184 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr14_+_103592663 0.181 NM_006291
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr18_-_45457454 0.175 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr15_-_34629044 0.175 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr15_-_34629941 0.173 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr15_+_67458492 0.171 NM_001145104
SMAD3
SMAD family member 3
chr15_+_67430358 0.164 NM_001145103
SMAD3
SMAD family member 3
chr2_-_206950895 0.164 NM_017759
INO80D
INO80 complex subunit D
chr15_+_67418053 0.161 NM_001145102
SMAD3
SMAD family member 3
chr15_+_67358194 0.158 NM_005902
SMAD3
SMAD family member 3
chr4_-_48782281 0.156 NM_015030
FRYL
FRY-like
chr3_+_151985828 0.152 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr1_-_161993586 0.148 NM_015441
OLFML2B
olfactomedin-like 2B
chr3_+_152017193 0.146 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr12_-_56652118 0.144 NM_173595
ANKRD52
ankyrin repeat domain 52
chr16_+_71879893 0.142 NM_001137675
ATXN1L
ataxin 1-like
chr12_-_44200047 0.142 NM_001242397
NM_002822
TWF1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr18_-_45456925 0.139 NM_005901
SMAD2
SMAD family member 2
chr21_-_18985224 0.137 NM_001130914
NM_006806
BTG3

BTG family, member 3

chr6_-_107435635 0.135 NM_001080450
BEND3
BEN domain containing 3
chr9_+_115913227 0.134 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr16_-_57219951 0.132 NM_024946
FAM192A
family with sequence similarity 192, member A
chr20_-_43977023 0.130 NM_002999
SDC4
syndecan 4
chr1_+_40839368 0.129 NM_022733
SMAP2
small ArfGAP2
chr13_-_26625164 0.128 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr5_+_102594406 0.123 NM_033211
C5orf30
chromosome 5 open reading frame 30
chr1_+_40859016 0.123 NM_001198979
SMAP2
small ArfGAP2
chr13_-_77601296 0.122 NM_012158
FBXL3
F-box and leucine-rich repeat protein 3
chr15_-_34610928 0.120 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chrX_+_77166178 0.119 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr4_+_183245136 0.117 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr1_+_42846427 0.116 NM_173642
RIMKLA
ribosomal modification protein rimK-like family member A
chr5_-_142815076 0.115 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr2_+_201983268 0.111 NM_001127183
CFLAR
CASP8 and FADD-like apoptosis regulator
chr15_+_39873276 0.110 NM_003246
THBS1
thrombospondin 1
chr2_+_115219153 0.110 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr5_-_142783225 0.108 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr2_+_231578262 0.107 NM_001130849
NM_001130850
CAB39

calcium binding protein 39

chr8_+_142432006 0.107 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr11_-_130184459 0.105 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr2_+_231577536 0.103 NM_016289
CAB39
calcium binding protein 39
chr2_+_115199898 0.103 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr2_-_9143742 0.102 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr1_+_163041694 0.102 NM_001113380
RGS4
regulator of G-protein signaling 4
chr2_+_115822246 0.101 NM_001178037
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr3_-_119812973 0.100 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr1_+_173684061 0.100 NM_014458
KLHL20
kelch-like 20 (Drosophila)
chrX_-_24045302 0.100 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr18_+_48086402 0.098 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr8_-_23021447 0.097 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr12_-_56583301 0.096 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chrX_+_150565655 0.094 NM_001017980
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr7_+_66386129 0.094 NM_017994
C7orf42
chromosome 7 open reading frame 42
chr2_+_201997687 0.094 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_202004997 0.094 NM_001202515
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_87794150 0.092 NM_006769
LMO4
LIM domain only 4
chr3_+_187930720 0.091 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_142783975 0.091 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_55646946 0.090 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr2_-_64881040 0.089 NM_014755
SERTAD2
SERTA domain containing 2
chr12_+_56360547 0.088 NM_001798
NM_052827
CDK2

cyclin-dependent kinase 2

chr1_-_55681024 0.088 NM_015306
USP24
ubiquitin specific peptidase 24
chr6_+_152126807 0.088 NM_001122741
ESR1
estrogen receptor 1
chr17_+_48423382 0.088 NM_022167
XYLT2
xylosyltransferase II
chr10_-_101945686 0.087 NM_006459
ERLIN1
ER lipid raft associated 1
chr17_+_68165660 0.087 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_163038395 0.085 NM_001102445
RGS4
regulator of G-protein signaling 4
chr2_+_63277191 0.084 NM_001199770
OTX1
orthodenticle homeobox 1
chr9_-_35563895 0.083 NM_001099951
NM_001164310
FAM166B

family with sequence similarity 166, member B

chr1_+_201708940 0.083 NM_001167738
NAV1
neuron navigator 1
chr1_+_163038564 0.083 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_-_202777545 0.082 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr2_+_115919512 0.082 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr12_+_109535377 0.082 NM_080911
UNG
uracil-DNA glycosylase
chr19_+_3572903 0.082 NM_006339
HMG20B
high mobility group 20B
chr3_+_187943192 0.082 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_40840304 0.082 NM_001198978
SMAP2
small ArfGAP2
chr8_-_81083660 0.079 NM_001025253
NM_005079
TPD52

tumor protein D52

chr1_-_109506016 0.079 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr2_+_85198176 0.079 NM_020122
KCMF1
potassium channel modulatory factor 1
chr12_+_109535922 0.079 NM_003362
UNG
uracil-DNA glycosylase
chr1_+_163038934 0.077 NM_001113381
RGS4
regulator of G-protein signaling 4
chr2_+_63277936 0.076 NM_014562
OTX1
orthodenticle homeobox 1
chr6_+_152128453 0.076 NM_001122740
ESR1
estrogen receptor 1
chr8_-_80993009 0.075 NM_001025252
TPD52
tumor protein D52
chr11_+_66886735 0.074 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr12_+_19592311 0.073 NM_001114176
NM_153207
AEBP2

AE binding protein 2

chr17_-_40307015 0.072 NM_001252039
NM_004583
NM_201434
RAB5C


RAB5C, member RAS oncogene family


chr6_+_152128685 0.069 NM_000125
ESR1
estrogen receptor 1
chr11_+_94822937 0.069 NM_015036
ENDOD1
endonuclease domain containing 1
chr1_+_40862471 0.069 NM_001198980
SMAP2
small ArfGAP2
chr10_-_101945787 0.069 NM_001100626
ERLIN1
ER lipid raft associated 1
chr15_+_73344824 0.066 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr1_+_16174358 0.064 NM_015001
SPEN
spen homolog, transcriptional regulator (Drosophila)
chr11_-_116968986 0.064 NM_025164
SIK3
SIK family kinase 3
chr6_-_86352635 0.062 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_35656677 0.062 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr6_+_112408673 0.061 NM_001033564
C6orf225
chromosome 6 open reading frame 225
chr2_-_26101301 0.060 NM_018263
ASXL2
additional sex combs like 2 (Drosophila)
chr1_+_90098643 0.060 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr5_-_171710794 0.060 NM_152277
UBTD2
ubiquitin domain containing 2
chr3_-_15900928 0.059 NM_015199
ANKRD28
ankyrin repeat domain 28
chr5_+_140044383 0.059 NM_017706
WDR55
WD repeat domain 55
chr6_-_24358279 0.057 NM_016356
DCDC2
doublecortin domain containing 2
chr5_+_122424840 0.057 NM_001136239
PRDM6
PR domain containing 6
chr4_-_7436614 0.057 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr12_-_29936685 0.057 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr3_-_51533996 0.057 NM_001171904
NM_014703
VPRBP

Vpr (HIV-1) binding protein

chr1_-_204329043 0.056 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_+_32573619 0.055 NM_012316
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr6_-_24383519 0.055 NM_001195610
DCDC2
doublecortin domain containing 2
chr19_+_9251052 0.055 NM_001190791
NM_020933
ZNF317

zinc finger protein 317

chr1_+_180601121 0.054 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chrX_+_108779009 0.054 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr6_+_152011630 0.053 NM_001122742
ESR1
estrogen receptor 1
chr12_-_29937691 0.053 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr3_-_15839674 0.053 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr5_-_158636489 0.053 NM_001199383
RNF145
ring finger protein 145
chr3_+_187871473 0.053 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_-_159240433 0.052 NM_001111077
EZR
ezrin
chr11_+_108093558 0.051 NM_000051
ATM
ataxia telangiectasia mutated
chr3_-_185542807 0.050 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr22_+_38092994 0.050 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr3_+_190105660 0.050 NM_006580
CLDN16
claudin 16
chr2_+_25264913 0.050 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr12_-_121736110 0.049 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr6_-_86352564 0.049 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr1_+_162467594 0.049 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr12_-_27167332 0.048 NM_016551
TM7SF3
transmembrane 7 superfamily member 3
chr6_+_80340971 0.048 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr1_+_33004771 0.047 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr1_+_201617449 0.047 NM_020443
NAV1
neuron navigator 1
chr3_+_85775631 0.046 NM_153184
CADM2
cell adhesion molecule 2
chr20_+_43104513 0.046 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr5_-_158637060 0.046 NM_001199380
RNF145
ring finger protein 145
chr3_+_171758289 0.045 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr14_+_103058988 0.044 NM_015156
RCOR1
REST corepressor 1
chr12_+_8850479 0.043 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr2_-_179343225 0.043 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr5_-_158635080 0.043 NM_001199381
RNF145
ring finger protein 145
chr11_-_108464344 0.042 NM_015065
EXPH5
exophilin 5
chrX_-_73834460 0.041 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr19_-_36523540 0.041 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr7_+_94536926 0.040 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr20_+_49348050 0.040 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr6_-_159239269 0.040 NM_003379
EZR
ezrin
chr16_+_69599868 0.040 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr11_-_59436488 0.039 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr3_-_168865521 0.039 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr4_+_108814419 0.039 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr5_-_158634833 0.039 NM_144726
RNF145
ring finger protein 145
chr9_-_93405066 0.039 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr5_-_137071703 0.038 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chrX_+_108780235 0.038 NM_001242618
NXT2
nuclear transport factor 2-like export factor 2
chr19_-_57678855 0.037 NM_001012729
DUXA
double homeobox A
chr4_-_42658883 0.037 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr16_+_85061303 0.036 NM_014732
KIAA0513
KIAA0513
chr9_+_115513050 0.036 NM_001012994
SNX30
sorting nexin family member 30
chr17_+_79373539 0.036 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr6_-_52441815 0.036 NM_012288
TRAM2
translocation associated membrane protein 2
chr4_+_157997181 0.036 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr5_+_56471272 0.035 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr7_+_94539209 0.035 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr12_-_129308293 0.035 NM_145648
SLC15A4
solute carrier family 15, member 4
chr5_+_77656338 0.034 NM_004866
SCAMP1
secretory carrier membrane protein 1
chr1_-_173962050 0.034 NM_172071
RC3H1
ring finger and CCCH-type domains 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.