Motif ID: ACAGUAC

Z-value: 0.987


Mature miRNA associated with seed ACAGUAC:

NamemiRBase Accession
hsa-miR-101 MIMAT0000099



Activity profile for motif ACAGUAC.

activity profile for motif ACAGUAC


Sorted Z-values histogram for motif ACAGUAC

Sorted Z-values for motif ACAGUAC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_58515408 2.087 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr20_+_58508818 2.061 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr1_-_186649421 2.024 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_82462374 1.488 NM_017633
FAM46A
family with sequence similarity 46, member A
chr6_-_134497069 1.434 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134496006 1.420 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134498973 1.411 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_88188261 1.401 NM_018293
ZNF654
zinc finger protein 654
chr6_-_134639195 1.384 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_185826748 1.313 NM_004454
ETV5
ets variant 5
chr5_-_59189620 1.305 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_169455099 1.249 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr5_-_58334936 1.246 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr8_-_22550057 1.231 NM_001199881
EGR3
early growth response 3
chr8_-_22549901 1.225 NM_001199880
EGR3
early growth response 3
chr11_-_86666211 1.212 NM_012193
FZD4
frizzled family receptor 4
chr2_+_45878912 1.208 NM_005400
PRKCE
protein kinase C, epsilon
chr8_-_22550708 1.174 NM_004430
EGR3
early growth response 3
chr3_-_178789597 1.171 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr5_-_58571916 1.152 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58652671 1.142 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 1.129 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_-_65155881 1.126 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_-_59783885 1.118 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58882274 1.065 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_59064437 1.033 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_172198160 1.023 NM_004417
DUSP1
dual specificity phosphatase 1
chr5_+_176560056 1.015 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr13_-_33760215 0.998 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33859835 0.979 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr13_-_33780142 0.976 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr5_+_60628085 0.962 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr20_-_31071187 0.894 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr19_-_31840118 0.874 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr10_+_97889467 0.832 NM_014803
ZNF518A
zinc finger protein 518A
chr5_+_176560627 0.823 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr18_+_60190657 0.747 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr14_+_75745480 0.717 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_197169635 0.713 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr14_+_85996454 0.666 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_-_108096693 0.653 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr2_-_172291227 0.646 NM_024770
METTL8
methyltransferase like 8
chr22_+_40440664 0.645 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr4_+_106067754 0.636 NM_001127208
TET2
tet methylcytosine dioxygenase 2
chr2_+_220094478 0.621 NM_018089
NM_001042410
ANKZF1

ankyrin repeat and zinc finger domain containing 1

chr4_-_18023358 0.597 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr7_-_5463176 0.592 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr6_+_121756744 0.586 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr4_-_153273683 0.584 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr4_-_153456152 0.583 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr7_-_47621741 0.578 NM_022748
TNS3
tensin 3
chr6_+_7107986 0.569 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr5_+_149151502 0.556 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr14_+_75894919 0.546 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr5_+_149109814 0.542 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr7_-_112727832 0.537 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr14_+_75894508 0.533 NM_001135047
JDP2
Jun dimerization protein 2
chr10_+_18549583 0.531 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_7107799 0.530 NM_001168344
RREB1
ras responsive element binding protein 1
chr9_-_138987096 0.528 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr8_-_30891230 0.527 NM_001015508
PURG
purine-rich element binding protein G
chr14_+_75898836 0.518 NM_001135049
JDP2
Jun dimerization protein 2
chr16_+_50186809 0.516 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr9_+_4490193 0.515 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr9_-_98269480 0.508 NM_001083607
PTCH1
patched 1
chr4_-_153303663 0.505 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr7_-_112726143 0.504 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr6_+_158733691 0.497 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr6_+_161412807 0.493 NM_005922
NM_006724
MAP3K4

mitogen-activated protein kinase kinase kinase 4

chr5_-_79286793 0.487 NM_001010891
NM_001167741
MTX3

metaxin 3

chr10_-_99393175 0.487 NM_178832
MORN4
MORN repeat containing 4
chr1_+_244216506 0.485 NM_006352
ZNF238
zinc finger protein 238
chr1_+_244214552 0.480 NM_205768
ZNF238
zinc finger protein 238
chr3_-_98620452 0.473 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr2_+_70142152 0.471 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr3_+_143692166 0.467 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr9_-_98270830 0.465 NM_000264
PTCH1
patched 1
chr6_+_11538486 0.463 NM_001100829
TMEM170B
transmembrane protein 170B
chr12_+_111843743 0.456 NM_005475
SH2B3
SH2B adaptor protein 3
chr9_+_116638544 0.454 NM_133374
ZNF618
zinc finger protein 618
chr13_-_79233266 0.451 NM_024546
RNF219
ring finger protein 219
chr1_+_198125890 0.450 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr6_+_138483024 0.448 NM_020340
KIAA1244
KIAA1244
chr3_+_23987514 0.446 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr20_+_32150139 0.440 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr8_-_127570710 0.435 NM_174911
FAM84B
family with sequence similarity 84, member B
chr4_-_80994309 0.432 NM_001145794
NM_058172
ANTXR2

anthrax toxin receptor 2

chr7_+_8008416 0.423 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr11_-_74660165 0.422 NM_182969
XRRA1
X-ray radiation resistance associated 1
chr4_-_170192193 0.420 NM_020870
SH3RF1
SH3 domain containing ring finger 1
chr1_+_162466963 0.419 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr19_+_48111437 0.418 NM_015711
GLTSCR1
glioma tumor suppressor candidate region gene 1
chr3_+_170139027 0.417 NM_001185056
CLDN11
claudin 11
chr7_+_100026412 0.416 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr14_+_45431333 0.412 NM_015091
FAM179B
family with sequence similarity 179, member B
chr9_-_98269686 0.408 NM_001083606
PTCH1
patched 1
chr21_-_36421586 0.401 NM_001754
RUNX1
runt-related transcription factor 1
chr7_+_100027253 0.400 NM_019606
MEPCE
methylphosphate capping enzyme
chr9_-_98270321 0.398 NM_001083604
NM_001083605
PTCH1

patched 1

chr4_+_15004297 0.395 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr3_+_107241782 0.395 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr1_+_162467594 0.395 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr18_+_8717368 0.395 NM_015210
CCDC165
coiled-coil domain containing 165
chr8_-_12990731 0.392 NM_006094
DLC1
deleted in liver cancer 1
chr10_+_18629613 0.391 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr10_-_105614952 0.385 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr1_-_156470506 0.384 NM_005920
MEF2D
myocyte enhancer factor 2D
chr12_-_76425375 0.382 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_-_124713693 0.378 NM_024942
C10orf88
chromosome 10 open reading frame 88
chr10_+_18429605 0.371 NM_201593
NM_201596
NM_201597
NM_001167945
NM_201571
NM_201572
CACNB2





calcium channel, voltage-dependent, beta 2 subunit





chr3_+_143690639 0.371 NM_173552
C3orf58
chromosome 3 open reading frame 58
chr8_-_12973752 0.369 NM_001164271
DLC1
deleted in liver cancer 1
chr1_+_65730423 0.368 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_65241305 0.368 NM_014877
HELZ
helicase with zinc finger
chr10_-_99393851 0.366 NM_001098831
MORN4
MORN repeat containing 4
chr1_+_116184573 0.365 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr17_+_30469373 0.365 NM_001033566
NM_001033568
NM_018307
RHOT1


ras homolog gene family, member T1


chr7_-_107880492 0.364 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr2_-_99279935 0.362 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr12_+_78225068 0.361 NM_014903
NAV3
neuron navigator 3
chr3_+_170136652 0.357 NM_005602
CLDN11
claudin 11
chr1_-_85725315 0.352 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr5_+_137688270 0.352 NM_016604
KDM3B
lysine (K)-specific demethylase 3B
chr4_+_95679075 0.351 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr16_+_58059281 0.351 NM_002428
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr5_+_139505519 0.350 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr6_-_85473898 0.345 NM_001080508
TBX18
T-box 18
chr1_+_116185249 0.344 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr11_-_95522945 0.342 NM_144664
FAM76B
family with sequence similarity 76, member B
chr10_+_60094712 0.341 NM_001204880
NM_003338
UBE2D1

ubiquitin-conjugating enzyme E2D 1

chr15_+_33603162 0.339 NM_001036
NM_001243996
RYR3

ryanodine receptor 3

chr10_+_74033676 0.338 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr5_+_153825497 0.333 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr21_-_15755439 0.333 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr20_+_32077904 0.329 NM_001032999
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr9_-_98279246 0.327 NM_001083602
NM_001083603
PTCH1

patched 1

chr7_-_127670995 0.322 NM_022143
LRRC4
leucine rich repeat containing 4
chr6_+_163148163 0.321 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr3_-_129612371 0.321 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr2_-_99347588 0.318 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_+_30524485 0.315 NM_001077497
NM_025263
PRR3

proline rich 3

chr12_+_4430346 0.312 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr13_+_98605928 0.311 NM_002271
IPO5
importin 5
chr4_+_8271458 0.309 NM_053044
HTRA3
HtrA serine peptidase 3
chr16_-_89556886 0.305 NM_013275
ANKRD11
ankyrin repeat domain 11
chr22_+_46546498 0.302 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr2_+_109065576 0.300 NM_181453
GCC2
GRIP and coiled-coil domain containing 2
chrX_+_144908927 0.296 NM_004709
CXorf1
chromosome X open reading frame 1
chr10_+_18689512 0.296 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_125633716 0.294 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr16_+_88493878 0.293 NM_001127464
ZNF469
zinc finger protein 469
chr9_-_134151905 0.292 NM_033387
FAM78A
family with sequence similarity 78, member A
chr13_+_33160537 0.290 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr6_+_71377471 0.289 NM_001044305
NM_021940
SMAP1

small ArfGAP 1

chr22_+_47022657 0.288 NM_015124
GRAMD4
GRAM domain containing 4
chr12_+_121124922 0.287 NM_014730
MLEC
malectin
chr8_-_74884500 0.284 NM_001204857
NM_001204858
NM_001204859
NM_001204860
NM_001204863
NM_001204864
NM_005648
TCEB1






transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)






chr17_+_36507708 0.282 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr3_-_69101236 0.282 NM_007114
TMF1
TATA element modulatory factor 1
chr2_+_60983354 0.280 NM_022894
PAPOLG
poly(A) polymerase gamma
chr5_-_40798263 0.276 NM_006251
NM_206907
PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

chr15_+_84322809 0.275 NM_207517
ADAMTSL3
ADAMTS-like 3
chr14_-_52535945 0.275 NM_007361
NID2
nidogen 2 (osteonidogen)
chr5_+_115177616 0.274 NM_001284
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr8_-_74884142 0.274 NM_001204861
NM_001204862
TCEB1

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

chr2_+_198381021 0.272 NM_001204094
MOB4
MOB family member 4, phocein
chr12_-_131002409 0.271 NM_015347
RIMBP2
RIMS binding protein 2
chr3_+_23986735 0.271 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr4_+_26862312 0.271 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr5_-_107006585 0.270 NM_001962
EFNA5
ephrin-A5
chr10_+_98592015 0.269 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr5_-_126366439 0.268 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chrX_-_109683457 0.267 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chrX_-_33229428 0.266 NM_004006
DMD
dystrophin
chr3_-_129599220 0.266 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_169075869 0.266 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_+_74056095 0.266 NM_006463
NM_213622
STAMBP

STAM binding protein

chr20_-_52199635 0.264 NM_006526
ZNF217
zinc finger protein 217
chr22_+_40573879 0.264 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr1_-_72748147 0.261 NM_173808
NEGR1
neuronal growth regulator 1
chr3_+_67048726 0.261 NM_032505
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr11_-_34379526 0.257 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr6_+_163149001 0.255 NM_001080379
PACRG
PARK2 co-regulated
chr6_-_111804413 0.252 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr19_+_10654591 0.252 NM_032885
ATG4D
ATG4 autophagy related 4 homolog D (S. cerevisiae)
chr7_-_105029321 0.251 NM_182692
SRPK2
SRSF protein kinase 2
chr7_-_149194896 0.250 NM_001163474
NM_152557
ZNF746

zinc finger protein 746

chrX_-_109561314 0.250 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr17_-_27169740 0.247 NM_001077498
NM_018182
C17orf63

chromosome 17 open reading frame 63

chrX_-_108976509 0.247 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr12_+_69004614 0.247 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr14_+_93673400 0.244 NM_175748
UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr8_-_95961543 0.242 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chrX_-_31526414 0.242 NM_004014
DMD
dystrophin
chr2_+_198380294 0.242 NM_199482
MOB4
MOB family member 4, phocein
chr9_-_6015606 0.241 NM_001243202
NM_001243203
NM_012416
RANBP6


RAN binding protein 6


chr12_-_76478737 0.241 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr5_+_148520985 0.238 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr7_-_104909442 0.237 NM_182691
SRPK2
SRSF protein kinase 2
chr14_-_27066959 0.235 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.56 5.88e-05 GO:0080090 regulation of primary metabolic process
1.71 7.03e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.68 1.33e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.52 4.33e-04 GO:0031323 regulation of cellular metabolic process
1.31 5.01e-04 GO:0050794 regulation of cellular process
1.53 5.87e-04 GO:0060255 regulation of macromolecule metabolic process
1.29 6.54e-04 GO:0050789 regulation of biological process
1.61 6.89e-04 GO:0031326 regulation of cellular biosynthetic process
2.19 1.10e-03 GO:0009891 positive regulation of biosynthetic process
1.59 1.18e-03 GO:0009889 regulation of biosynthetic process
1.60 1.27e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 1.42e-03 GO:0019222 regulation of metabolic process
2.23 1.65e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.18 1.69e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.60 1.90e-03 GO:0010468 regulation of gene expression
1.56 2.83e-03 GO:0051171 regulation of nitrogen compound metabolic process
2.23 3.07e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.19 4.73e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.33 5.06e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 5.13e-03 GO:0065007 biological regulation
2.00 7.60e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.24 9.45e-03 GO:0051254 positive regulation of RNA metabolic process
2.22 1.18e-02 GO:0010628 positive regulation of gene expression
1.59 1.42e-02 GO:0051252 regulation of RNA metabolic process
1.59 1.91e-02 GO:0006355 regulation of transcription, DNA-dependent
2.16 2.07e-02 GO:0009790 embryo development
2.43 2.27e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.84 3.13e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.74 3.38e-02 GO:0009966 regulation of signal transduction
1.43 3.45e-02 GO:0007275 multicellular organismal development
2.19 3.46e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.79 3.88e-02 GO:0009893 positive regulation of metabolic process
2.20 4.30e-02 GO:0010629 negative regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 4.77e-04 GO:0005634 nucleus
1.15 1.71e-03 GO:0005622 intracellular
1.15 4.69e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.44 2.34e-08 GO:0030528 transcription regulator activity
1.19 7.24e-07 GO:0005488 binding
2.22 8.89e-06 GO:0001071 nucleic acid binding transcription factor activity
2.22 8.89e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.45 3.21e-05 GO:0043565 sequence-specific DNA binding
1.49 3.41e-05 GO:0046872 metal ion binding
1.47 6.93e-05 GO:0043169 cation binding
1.47 8.07e-05 GO:0043167 ion binding
1.51 1.99e-04 GO:0003676 nucleic acid binding
1.64 1.15e-03 GO:0008270 zinc ion binding
1.58 1.60e-03 GO:0003677 DNA binding
1.26 1.82e-03 GO:0005515 protein binding
2.87 2.16e-03 GO:0016564 transcription repressor activity
1.53 9.27e-03 GO:0046914 transition metal ion binding
2.56 3.00e-02 GO:0016563 transcription activator activity
2.74 3.90e-02 GO:0003702 RNA polymerase II transcription factor activity