Motif ID: AGCAGCA

Z-value: 2.011


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a MIMAT0000068
hsa-miR-15b MIMAT0000417
hsa-miR-16 MIMAT0000069
hsa-miR-195 MIMAT0000461
hsa-miR-424 MIMAT0001341
hsa-miR-497 MIMAT0002820



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_76944585 8.895 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr11_+_69455837 6.644 NM_053056
CCND1
cyclin D1
chr12_-_105322056 6.068 NM_032148
SLC41A2
solute carrier family 41, member 2
chr1_+_65613771 5.414 NM_013410
AK4
adenylate kinase 4
chr1_+_65613211 5.362 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr3_-_123603144 4.803 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr6_-_134498973 4.722 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134639195 4.722 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134496006 4.701 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134497069 4.652 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_123339423 4.509 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr19_-_49222956 4.219 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr19_-_49220213 4.197 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_+_112812799 3.733 NM_032824
TMEM87B
transmembrane protein 87B
chr7_-_83824216 3.602 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_201438150 3.349 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr5_+_127419407 3.298 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr8_+_31497267 3.196 NM_013962
NRG1
neuregulin 1
chr1_+_145438437 3.193 NM_006472
TXNIP
thioredoxin interacting protein
chr22_-_42017032 2.984 NM_015704
PPPDE2
PPPDE peptidase domain containing 2
chr8_+_32504250 2.972 NM_013959
NRG1
neuregulin 1
chr17_-_28562953 2.708 NM_001045
SLC6A4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr8_+_17354562 2.676 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17396285 2.558 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr3_-_178789597 2.536 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr2_+_210636700 2.517 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr4_-_153273683 2.499 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_+_209848659 2.418 NM_015714
G0S2
G0/G1switch 2
chr22_-_28197469 2.400 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr17_+_40834571 2.372 NM_003632
CNTNAP1
contactin associated protein 1
chr6_+_7107986 2.349 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr22_+_39101806 2.343 NM_004286
GTPBP1
GTP binding protein 1
chr3_+_88188261 2.313 NM_018293
ZNF654
zinc finger protein 654
chr9_+_118916069 2.285 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_+_173116243 2.283 NM_014932
NLGN1
neuroligin 1
chr4_+_128703402 2.272 NM_014278
HSPA4L
heat shock 70kDa protein 4-like
chr1_+_28585959 2.260 NM_031459
SESN2
sestrin 2
chr6_+_7107799 2.241 NM_001168344
RREB1
ras responsive element binding protein 1
chr8_+_144099900 2.200 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr18_-_46477080 2.187 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr12_+_4382882 2.159 NM_001759
CCND2
cyclin D2
chr13_-_33760215 2.118 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr7_-_139477437 2.111 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr11_-_65667860 2.096 NM_005438
FOSL1
FOS-like antigen 1
chr1_+_26438267 2.080 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr4_-_153456152 2.071 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr13_-_33859835 2.070 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_-_86666211 2.056 NM_012193
FZD4
frizzled family receptor 4
chr4_-_185747183 2.055 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_-_197169635 2.048 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr13_-_33780142 2.043 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr5_-_95297597 2.033 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr6_+_11094265 2.013 NM_001135575
C6orf228
chromosome 6 open reading frame 228
chr4_+_15004297 1.992 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr17_+_36861857 1.950 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr18_-_46475702 1.940 NM_001190822
SMAD7
SMAD family member 7
chr11_-_34379526 1.934 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr20_-_31071187 1.925 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr1_+_184356128 1.846 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr6_-_109330752 1.841 NM_001199933
SESN1
sestrin 1
chr18_-_46469118 1.817 NM_001190823
SMAD7
SMAD family member 7
chr20_+_44486219 1.787 NM_080752
ZSWIM3
zinc finger, SWIM-type containing 3
chr6_-_109415514 1.773 NM_014454
SESN1
sestrin 1
chr4_+_142557722 1.769 NM_000585
NM_172175
IL15

interleukin 15

chr20_-_3996035 1.742 NM_007219
NM_001134337
NM_001134338
RNF24


ring finger protein 24


chr1_-_156785938 1.711 NM_001161443
SH2D2A
SH2 domain containing 2A
chr1_-_120612301 1.704 NM_001200001
NM_024408
NOTCH2

notch 2

chr15_+_59063389 1.703 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr1_-_149908098 1.687 NM_181873
MTMR11
myotubularin related protein 11
chr19_+_30302861 1.672 NM_001238
CCNE1
cyclin E1
chr7_+_90032647 1.652 NM_001185072
NM_001185073
NM_012129
CLDN12


claudin 12


chr6_-_109330190 1.627 NM_001199934
SESN1
sestrin 1
chr15_+_41245635 1.625 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr1_+_27561006 1.610 NM_015023
WDTC1
WD and tetratricopeptide repeats 1
chrX_+_68048792 1.603 NM_004429
EFNB1
ephrin-B1
chr11_-_16424391 1.600 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr9_+_504661 1.599 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr4_-_79860369 1.590 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr5_+_67586466 1.566 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr17_-_62658311 1.553 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr9_+_102668904 1.540 NM_017919
STX17
syntaxin 17
chr15_+_66679107 1.533 NM_002755
MAP2K1
mitogen-activated protein kinase kinase 1
chr11_+_65082288 1.524 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_149908759 1.519 NM_001145862
MTMR11
myotubularin related protein 11
chr6_+_34204576 1.509 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr6_+_34206567 1.506 NM_145905
HMGA1
high mobility group AT-hook 1
chr17_+_57232859 1.497 NM_018304
PRR11
proline rich 11
chr8_+_22457098 1.489 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr17_-_27916602 1.488 NM_001085454
NM_014030
GIT1

G protein-coupled receptor kinase interacting ArfGAP 1

chr9_+_132934685 1.484 NM_014286
NCS1
neuronal calcium sensor 1
chr12_+_21654698 1.471 NM_016072
GOLT1B
golgi transport 1B
chr1_-_23495347 1.462 NM_001142546
NM_033631
LUZP1

leucine zipper protein 1

chr5_-_16465856 1.457 NM_033414
ZNF622
zinc finger protein 622
chr17_-_1395950 1.452 NM_001080779
MYO1C
myosin IC
chr2_+_148602569 1.451 NM_001616
ACVR2A
activin A receptor, type IIA
chr2_-_73340073 1.446 NM_015470
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr9_+_706744 1.444 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr17_-_1394849 1.433 NM_033375
MYO1C
myosin IC
chr1_+_167298280 1.419 NM_001198783
POU2F1
POU class 2 homeobox 1
chr10_+_92980322 1.409 NM_032373
PCGF5
polycomb group ring finger 5
chr10_-_119805673 1.403 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr3_+_6902797 1.390 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr10_+_98592015 1.390 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr9_-_27529434 1.386 NM_024761
MOB3B
MOB kinase activator 3B
chr6_+_34204647 1.370 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr12_+_6833149 1.369 NM_001164094
NM_016319
NM_001164095
COPS7A


COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)


chr18_-_24220307 1.367 NM_198991
KCTD1
potassium channel tetramerisation domain containing 1
chr10_+_98592658 1.364 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr12_+_6833425 1.362 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr4_+_140222668 1.359 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr5_+_67588395 1.354 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_67511578 1.342 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_72852957 1.339 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr14_-_74253876 1.319 NM_001043318
C14orf43
chromosome 14 open reading frame 43
chr9_-_140353785 1.317 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr12_+_122242580 1.311 NM_015048
SETD1B
SET domain containing 1B
chr12_+_62654120 1.311 NM_001252078
NM_001252079
NM_006313
USP15


ubiquitin specific peptidase 15


chr18_-_61034350 1.310 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr4_+_25235651 1.309 NM_018323
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr1_-_156721501 1.300 NM_004494
HDGF
hepatoma-derived growth factor
chrX_+_64708614 1.297 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr17_-_56595192 1.294 NM_004687
MTMR4
myotubularin related protein 4
chr16_+_57406398 1.279 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr2_+_73441344 1.272 NM_006062
SMYD5
SMYD family member 5
chr19_+_4229494 1.272 NM_005755
EBI3
Epstein-Barr virus induced 3
chr12_-_77459198 1.270 NM_203394
E2F7
E2F transcription factor 7
chr1_-_156722023 1.265 NM_001126051
NM_001126050
HDGF

hepatoma-derived growth factor

chr3_-_98620452 1.265 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chrX_-_103087106 1.262 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr5_+_67584251 1.260 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_-_108976509 1.246 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr18_-_24129084 1.235 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr21_+_45285101 1.232 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr9_+_117373622 1.232 NM_153045
C9orf91
chromosome 9 open reading frame 91
chr1_+_167189948 1.228 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr16_-_73092533 1.224 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_-_798196 1.222 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr15_-_78369825 1.217 NM_015079
NM_144572
TBC1D2B

TBC1 domain family, member 2B

chr11_-_797955 1.215 NM_001191060
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr4_-_56412968 1.214 NM_004898
CLOCK
clock homolog (mouse)
chr3_+_29322802 1.210 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr16_-_11680756 1.204 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr3_-_48229800 1.195 NM_001789
NM_201567
CDC25A

cell division cycle 25 homolog A (S. pombe)

chr2_-_46384 1.194 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr15_+_69706619 1.191 NM_004856
NM_138555
KIF23

kinesin family member 23

chr6_-_119031230 1.190 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr21_-_36421586 1.188 NM_001754
RUNX1
runt-related transcription factor 1
chr7_-_131241321 1.172 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr7_-_25019625 1.169 NM_015550
NM_145320
NM_145321
NM_145322
OSBPL3



oxysterol binding protein-like 3



chr22_-_41985810 1.164 NM_002676
PMM1
phosphomannomutase 1
chr7_+_143078358 1.163 NM_001010972
NM_003461
ZYX

zyxin

chr9_+_132962871 1.162 NM_001128826
NCS1
neuronal calcium sensor 1
chr3_-_36986535 1.148 NM_014831
TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
chrX_+_152599544 1.139 NM_001080485
ZNF275
zinc finger protein 275
chr9_-_127905715 1.136 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr15_+_84322809 1.133 NM_207517
ADAMTSL3
ADAMTS-like 3
chr1_-_36915969 1.128 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr5_+_172068188 1.125 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr7_-_92463211 1.123 NM_001259
CDK6
cyclin-dependent kinase 6
chr1_-_156786500 1.122 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr1_-_200992824 1.109 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr18_+_55102777 1.104 NM_004852
ONECUT2
one cut homeobox 2
chr5_+_139493689 1.104 NM_005859
PURA
purine-rich element binding protein A
chr14_+_32546445 1.103 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chrX_+_49832214 1.103 NM_000084
CLCN5
chloride channel 5
chr15_+_67358194 1.100 NM_005902
SMAD3
SMAD family member 3
chr17_-_1733083 1.098 NM_052928
SMYD4
SET and MYND domain containing 4
chr11_-_118023534 1.094 NM_001142348
NM_174934
SCN4B

sodium channel, voltage-gated, type IV, beta

chr21_+_45345278 1.091 NM_001037553
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr15_+_71433787 1.090 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr17_-_1389013 1.090 NM_001080950
MYO1C
myosin IC
chr1_+_206680863 1.089 NM_182663
NM_182664
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr6_+_134274247 1.082 NM_004865
TBPL1
TBP-like 1
chr8_-_57123858 1.074 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr3_-_160283361 1.074 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr16_-_48644087 1.073 NM_153029
N4BP1
NEDD4 binding protein 1
chr20_+_43374487 1.073 NM_022358
KCNK15
potassium channel, subfamily K, member 15
chr4_-_153303663 1.068 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr10_+_101419169 1.067 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr5_-_59189620 1.063 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_208529 1.063 NM_021932
RIC8A
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
chr1_+_15853348 1.061 NM_015291
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr9_+_131843378 1.061 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr19_-_1848447 1.059 NM_020695
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr12_-_53473171 1.048 NM_032840
SPRYD3
SPRY domain containing 3
chr19_+_6739697 1.044 NM_004240
TRIP10
thyroid hormone receptor interactor 10
chr1_-_151300132 1.042 NM_001198773
NM_001198775
NM_002651
PI4KB


phosphatidylinositol 4-kinase, catalytic, beta


chr2_-_2334887 1.034 NM_015025
MYT1L
myelin transcription factor 1-like
chr12_-_26277807 1.034 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr6_+_127440047 1.031 NM_032784
RSPO3
R-spondin 3
chr18_+_29672568 1.031 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr10_-_35379480 1.030 NM_001198777
CUL2
cullin 2
chr7_-_103629962 1.029 NM_005045
NM_173054
RELN

reelin

chr7_-_139763520 1.023 NM_022750
PARP12
poly (ADP-ribose) polymerase family, member 12
chr7_-_92465929 1.019 NM_001145306
CDK6
cyclin-dependent kinase 6
chr8_-_122653493 1.018 NM_005328
HAS2
hyaluronan synthase 2
chr8_+_104310660 1.016 NM_001164615
FZD6
frizzled family receptor 6
chr16_-_11680146 1.015 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr9_-_136857285 1.009 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr8_+_104311058 1.008 NM_001164616
NM_003506
FZD6

frizzled family receptor 6


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 5.45e-07 GO:0023052 signaling
1.14 1.24e-06 GO:0009987 cellular process
1.23 1.92e-06 GO:0050794 regulation of cellular process
1.21 4.20e-06 GO:0065007 biological regulation
1.21 7.55e-06 GO:0050789 regulation of biological process
1.56 4.53e-05 GO:0023051 regulation of signaling
1.94 5.00e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.58 6.58e-05 GO:0007399 nervous system development
2.02 1.60e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.46 2.56e-04 GO:0030154 cell differentiation
1.29 3.52e-04 GO:0051716 cellular response to stimulus
1.54 3.58e-04 GO:0009653 anatomical structure morphogenesis
1.44 4.28e-04 GO:0048869 cellular developmental process
3.04 4.63e-04 GO:0008286 insulin receptor signaling pathway
1.33 4.89e-04 GO:0007165 signal transduction
1.55 7.26e-04 GO:0009966 regulation of signal transduction
1.40 7.49e-04 GO:0048522 positive regulation of cellular process
1.31 8.93e-04 GO:0051179 localization
2.69 1.07e-03 GO:0032869 cellular response to insulin stimulus
1.30 1.08e-03 GO:0032502 developmental process
2.91 1.96e-03 GO:0016055 Wnt receptor signaling pathway
1.32 2.39e-03 GO:0048856 anatomical structure development
1.35 3.31e-03 GO:0048518 positive regulation of biological process
1.40 3.69e-03 GO:0048523 negative regulation of cellular process
1.33 5.16e-03 GO:0048731 system development
1.66 6.04e-03 GO:0048699 generation of neurons
1.74 6.06e-03 GO:0019220 regulation of phosphate metabolic process
1.74 6.06e-03 GO:0051174 regulation of phosphorus metabolic process
1.74 6.42e-03 GO:0030182 neuron differentiation
1.28 6.83e-03 GO:0031323 regulation of cellular metabolic process
1.29 6.84e-03 GO:0007275 multicellular organismal development
1.27 7.89e-03 GO:0019222 regulation of metabolic process
1.31 7.89e-03 GO:0051234 establishment of localization
1.59 8.03e-03 GO:0032268 regulation of cellular protein metabolic process
1.62 1.14e-02 GO:0022008 neurogenesis
1.72 1.49e-02 GO:0042325 regulation of phosphorylation
1.74 1.54e-02 GO:0030030 cell projection organization
1.35 1.57e-02 GO:0048519 negative regulation of biological process
1.27 1.73e-02 GO:0080090 regulation of primary metabolic process
1.58 1.83e-02 GO:0042127 regulation of cell proliferation
1.64 2.26e-02 GO:0031399 regulation of protein modification process
1.30 2.30e-02 GO:0006810 transport
1.73 2.34e-02 GO:0001932 regulation of protein phosphorylation
1.28 2.34e-02 GO:0060255 regulation of macromolecule metabolic process
1.39 2.48e-02 GO:0048583 regulation of response to stimulus
1.76 2.72e-02 GO:0048666 neuron development
1.53 3.73e-02 GO:0051246 regulation of protein metabolic process
1.81 3.91e-02 GO:0031175 neuron projection development
1.54 4.59e-02 GO:0007154 cell communication
1.57 4.82e-02 GO:0048468 cell development
1.47 4.84e-02 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 6.37e-07 GO:0005622 intracellular
1.12 7.52e-06 GO:0044424 intracellular part
1.33 2.95e-04 GO:0043234 protein complex
1.47 7.79e-04 GO:0005856 cytoskeleton
1.14 2.14e-03 GO:0005737 cytoplasm
1.12 2.30e-03 GO:0043229 intracellular organelle
1.12 3.12e-03 GO:0043226 organelle
1.05 3.99e-03 GO:0044464 cell part
1.05 4.09e-03 GO:0005623 cell
2.01 1.35e-02 GO:0005874 microtubule
1.28 2.35e-02 GO:0043228 non-membrane-bounded organelle
1.28 2.35e-02 GO:0043232 intracellular non-membrane-bounded organelle
6.07 2.77e-02 GO:0000307 cyclin-dependent protein kinase holoenzyme complex
1.17 3.04e-02 GO:0005634 nucleus
1.31 3.38e-02 GO:0044459 plasma membrane part
1.23 3.48e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.26 1.18e-10 GO:0005515 protein binding
1.10 2.13e-04 GO:0005488 binding
2.82 5.23e-03 GO:0051020 GTPase binding
3.08 5.71e-03 GO:0017016 Ras GTPase binding
2.92 7.76e-03 GO:0031267 small GTPase binding
2.13 8.80e-03 GO:0005096 GTPase activator activity
1.79 1.43e-02 GO:0030695 GTPase regulator activity
3.93 1.95e-02 GO:0046332 SMAD binding
1.75 2.97e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.58 3.03e-02 GO:0019899 enzyme binding