Motif ID: ATF2.p2

Z-value: 1.019


Transcription factors associated with ATF2.p2:

Gene SymbolEntrez IDGene Name
ATF2 1386 activating transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ATF2chr2_-_176032850-0.262.0e-01Click!


Activity profile for motif ATF2.p2.

activity profile for motif ATF2.p2


Sorted Z-values histogram for motif ATF2.p2

Sorted Z-values for motif ATF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_41700736 7.663 LIMCH1
LIM and calponin homology domains 1
chr10_+_35484054 4.184 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr13_+_32605436 4.087 NM_023037
FRY
furry homolog (Drosophila)
chr12_+_27397077 3.758 NM_015000
STK38L
serine/threonine kinase 38 like
chr10_+_35484829 3.719 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr3_+_8543508 3.573 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr3_-_64211111 3.378 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr20_-_39317875 2.723 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr9_-_14086901 2.460 NFIB
nuclear factor I/B
chr2_-_188312872 2.363 NM_005795
CALCRL
calcitonin receptor-like
chr3_+_8543539 2.298 LMCD1
LIM and cysteine-rich domains 1
chr7_+_89843133 2.225 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr18_+_77155714 1.979 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr14_+_56584854 1.943 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr14_+_56585147 1.941 PELI2
pellino homolog 2 (Drosophila)
chr8_-_93111915 1.905 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_112849352 1.853 NM_022828
YTHDC2
YTH domain containing 2
chr19_+_45971249 1.827 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_+_212209129 1.799 DTL
denticleless homolog (Drosophila)
chr17_+_56769929 1.798 RAD51C
RAD51 homolog C (S. cerevisiae)
chr18_+_77155927 1.797 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr13_-_45010937 1.747 TSC22D1
TSC22 domain family, member 1
chr1_+_119683006 1.724


chr16_-_4588738 1.724 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr1_-_76076762 1.709 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr10_-_95360959 1.695 NM_006744
RBP4
retinol binding protein 4, plasma
chr17_+_56769953 1.669 NM_002876
NM_058216
RAD51C

RAD51 homolog C (S. cerevisiae)

chr2_+_132480063 1.668 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr3_+_170075494 1.593 SKIL
SKI-like oncogene
chr7_-_129592794 1.530 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr3_+_170075449 1.527 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr1_+_84647342 1.526 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_52082755 1.519 OSBPL9
oxysterol binding protein-like 9
chr1_-_76397975 1.513 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chrX_+_118108575 1.487 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr5_-_111091947 1.466 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr5_+_68710938 1.461 NM_001038603
NM_001244734
MARVELD2

MARVEL domain containing 2

chr9_+_125027152 1.448 MRRF
mitochondrial ribosome recycling factor
chr12_-_46121248 1.444 LOC400027
uncharacterized LOC400027
chr18_+_77160243 1.415 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr14_+_68086633 1.412 ARG2
arginase, type II
chr14_-_77494974 1.394 NM_024496
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr18_+_77155943 1.383 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_-_125027080 1.370 NM_033117
RBM18
RNA binding motif protein 18
chr7_-_129592711 1.366 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr6_+_136172802 1.361 NM_018945
PDE7B
phosphodiesterase 7B
chr1_+_212209112 1.310 DTL
denticleless homolog (Drosophila)
chr10_+_35416089 1.278 CREM
cAMP responsive element modulator
chr13_-_48987247 1.261 LPAR6
lysophosphatidic acid receptor 6
chr4_+_170581212 1.259 NM_001243374
CLCN3
chloride channel 3
chr2_-_27531113 1.233 NM_003353
UCN
urocortin
chr1_+_212208918 1.227 NM_016448
DTL
denticleless homolog (Drosophila)
chr17_+_40913211 1.218 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr11_+_12695851 1.206 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr14_+_61447831 1.156 NM_001172702
NM_153811
SLC38A6

solute carrier family 38, member 6

chr9_+_131644427 1.139 LRRC8A
leucine rich repeat containing 8 family, member A
chr9_-_125027017 1.120 RBM18
RNA binding motif protein 18
chr12_-_31881949 1.118 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr13_-_48987017 1.108 LPAR6
lysophosphatidic acid receptor 6
chr11_-_18343670 1.086 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr7_-_100808832 1.079 NM_003378
VGF
VGF nerve growth factor inducible
chr2_-_157189040 1.070 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_-_124774735 1.059 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr14_+_61447929 1.046 SLC38A6
solute carrier family 38, member 6
chr17_+_25621105 1.045 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr11_-_89224413 1.044 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr9_+_131644368 1.031 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr8_-_95274540 1.023 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr5_-_140012730 1.021 CD14
CD14 molecule
chr12_+_56915587 1.018 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr4_-_170533762 1.012 NM_001199397
NM_001199398
NM_001199399
NM_001199400
NM_012224
NEK1




NIMA (never in mitosis gene a)-related kinase 1




chr1_+_2005083 1.011 NM_001033581
PRKCZ
protein kinase C, zeta
chr5_-_138210992 0.998 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr9_-_126030854 0.994 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr5_+_126112314 0.984 NM_005573
LMNB1
lamin B1
chr9_-_126030792 0.967 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr3_+_132318980 0.963 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr5_-_132948195 0.960 FSTL4
follistatin-like 4
chr6_+_148663728 0.947 NM_015278
SASH1
SAM and SH3 domain containing 1
chr12_-_31882006 0.947 NM_001113402
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr1_+_229440128 0.930 NM_006542
SPHAR
S-phase response (cyclin related)
chr6_+_39760138 0.918


chr3_+_170075521 0.912 SKIL
SKI-like oncogene
chr18_+_77155966 0.899 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr4_+_145567147 0.894 NM_022475
HHIP
hedgehog interacting protein
chr19_-_47617008 0.888 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr22_+_31518923 0.875 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chrX_-_10645726 0.874 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_66798095 0.870 PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_44588622 0.866 NM_001171606
NM_001171613
PREPL

prolyl endopeptidase-like

chr11_+_9596233 0.863 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr9_-_129884998 0.850 NM_012098
ANGPTL2
angiopoietin-like 2
chr4_-_54424402 0.842 NM_032622
LNX1
ligand of numb-protein X 1
chr13_-_29069215 0.839 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr12_-_42877785 0.836 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr5_-_140013285 0.834 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr6_+_147527102 0.819 STXBP5
syntaxin binding protein 5 (tomosyn)
chr9_-_129884885 0.813 ANGPTL2
angiopoietin-like 2
chr4_-_170533536 0.808 NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr14_+_68086655 0.806 ARG2
arginase, type II
chr18_-_33647521 0.804 RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr2_-_21022812 0.792 NM_021925
C2orf43
chromosome 2 open reading frame 43
chr11_-_33913835 0.790 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_-_50979461 0.788 FAM71E1
family with sequence similarity 71, member E1
chr5_-_14871555 0.782 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr4_-_54424345 0.780 LNX1
ligand of numb-protein X 1
chr20_+_33759773 0.775 NM_006404
PROCR
protein C receptor, endothelial
chr5_-_172198160 0.770 NM_004417
DUSP1
dual specificity phosphatase 1
chrX_+_102585113 0.769 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr14_+_68086570 0.765 NM_001172
ARG2
arginase, type II
chr6_-_70506524 0.764 LMBRD1
LMBR1 domain containing 1
chr1_-_204121144 0.761 NM_018208
ETNK2
ethanolamine kinase 2
chr20_+_10199455 0.758 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr1_-_229644077 0.758 NM_018230
NUP133
nucleoporin 133kDa
chr6_-_70506768 0.756 LMBRD1
LMBR1 domain containing 1
chr13_-_48987652 0.755 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr9_-_113100076 0.755 NM_001003936
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr8_-_95274520 0.751 GEM
GTP binding protein overexpressed in skeletal muscle
chr11_+_18343794 0.742 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr9_+_127420690 0.736 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr20_+_17949529 0.735 NM_052865
C20orf72
chromosome 20 open reading frame 72
chr14_-_36278335 0.727 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr14_+_61447949 0.714 SLC38A6
solute carrier family 38, member 6
chr4_-_70725792 0.712 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr14_+_101292483 0.708


chr3_+_23987514 0.708 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr8_-_28243941 0.702 NM_018660
ZNF395
zinc finger protein 395
chr20_+_4666796 0.694 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr2_+_11052062 0.693 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr8_-_117768059 0.693 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr14_+_102276279 0.690 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr9_+_137967401 0.681 OLFM1
olfactomedin 1
chr18_-_33647519 0.680 RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr5_-_138211054 0.670 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr1_-_212208779 0.663 NM_001199809
NM_001199811
NM_001199812
NM_015434
INTS7



integrator complex subunit 7



chr1_-_209979388 0.662 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr12_-_102455793 0.659 NM_016053
CCDC53
coiled-coil domain containing 53
chr8_-_102803196 0.657 NCALD
neurocalcin delta
chr6_-_70506843 0.656 NM_018368
LMBRD1
LMBR1 domain containing 1
chr12_-_46121489 0.656 LOC400027
uncharacterized LOC400027
chr17_-_7165788 0.655 CLDN7
claudin 7
chr1_-_173837122 0.650 GAS5
growth arrest-specific 5 (non-protein coding)
chr12_+_56521953 0.650 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chr7_+_150690838 0.647 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr1_+_203274646 0.645 NM_006763
BTG2
BTG family, member 2
chr17_-_47841517 0.640 NM_030802
FAM117A
family with sequence similarity 117, member A
chr18_-_33647336 0.636 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr20_-_44600939 0.633 ZNF335
zinc finger protein 335
chr10_+_112344076 0.630 SMC3
structural maintenance of chromosomes 3
chr9_-_8733893 0.629 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr7_+_116660263 0.622 ST7
suppression of tumorigenicity 7
chr8_-_117768032 0.622 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr6_-_134373618 0.621 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr14_+_63671101 0.619 NM_020663
RHOJ
ras homolog gene family, member J
chr15_+_65914269 0.619 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr2_-_133429069 0.617 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr16_-_4588379 0.616 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr11_+_118230292 0.612 NM_001204077
NM_004788
UBE4A

ubiquitination factor E4A

chr19_-_36036390 0.610 LOC100506469
uncharacterized LOC100506469
chr2_-_220408264 0.603 NM_024536
CHPF
chondroitin polymerizing factor
chr13_-_52378230 0.602 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr12_+_56522049 0.601 ESYT1
extended synaptotagmin-like protein 1
chr12_+_10365415 0.596 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_+_4643318 0.594 NM_001136046
NM_032265
ZMYND15

zinc finger, MYND-type containing 15

chr16_-_86588680 0.593 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr17_+_33914278 0.592 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr15_-_82336880 0.592 MEX3B
mex-3 homolog B (C. elegans)
chrX_+_118108595 0.581 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr22_+_25003610 0.576 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr2_-_27712520 0.576 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr11_-_62474810 0.574 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_148663953 0.574 SASH1
SAM and SH3 domain containing 1
chr6_-_41888858 0.571 NM_004275
MED20
mediator complex subunit 20
chr7_-_23571443 0.571 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chrX_+_102192199 0.568 NM_001031834
RAB40AL
RAB40A, member RAS oncogene family-like
chr12_-_102455763 0.567 CCDC53
coiled-coil domain containing 53
chr3_+_25469833 0.565 NM_000965
RARB
retinoic acid receptor, beta
chr14_+_93651295 0.565 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr14_+_102276125 0.563 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr12_-_14996381 0.558 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr11_-_82782883 0.558 NM_014488
RAB30
RAB30, member RAS oncogene family
chr13_+_103249285 0.557 NM_003291
TPP2
tripeptidyl peptidase II
chr12_+_56522043 0.557 ESYT1
extended synaptotagmin-like protein 1
chr11_-_118123001 0.556 NM_198275
MPZL3
myelin protein zero-like 3
chr6_-_41888680 0.550 MED20
mediator complex subunit 20
chr2_+_207139413 0.548 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr3_+_44803280 0.545 KIF15
kinesin family member 15
chr5_+_99871023 0.545 NM_198507
FAM174A
family with sequence similarity 174, member A
chr5_+_73109342 0.541 NM_001244364
RGNEF
190 kDa guanine nucleotide exchange factor
chrX_+_152240726 0.536 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr3_+_141457110 0.533 RNF7
ring finger protein 7
chr5_+_140165875 0.528 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr9_+_132251403 0.527 LOC100506190
uncharacterized LOC100506190
chr7_+_130131172 0.527 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr1_-_229643996 0.525 NUP133
nucleoporin 133kDa
chr1_+_66797775 0.524 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_44803208 0.520 NM_020242
KIF15
kinesin family member 15
chr6_-_56407681 0.519


chr12_+_7282963 0.517 NM_014718
CLSTN3
calsyntenin 3
chr2_+_109271484 0.517 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 1.48e-02 GO:0007275 multicellular organismal development
1.30 1.84e-02 GO:0032502 developmental process
1.33 1.85e-02 GO:0048856 anatomical structure development
1.34 4.26e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.38e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 1.27e-02 GO:0005488 binding