Motif ID: CGUACCG

Z-value: 0.175


Mature miRNA associated with seed CGUACCG:

NamemiRBase Accession
hsa-miR-126 MIMAT0000445



Activity profile for motif CGUACCG.

activity profile for motif CGUACCG


Sorted Z-values histogram for motif CGUACCG

Sorted Z-values for motif CGUACCG



Network of associatons between targets according to the STRING database.



First level regulatory network of CGUACCG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_116356199 0.116 NM_144489
RGS3
regulator of G-protein signaling 3
chr9_+_116207010 0.114 NM_144488
RGS3
regulator of G-protein signaling 3
chr9_+_116327301 0.109 NM_134427
RGS3
regulator of G-protein signaling 3
chr9_+_116342939 0.109 NM_021106
RGS3
regulator of G-protein signaling 3
chr22_+_35695267 0.106 NM_001135729
TOM1
target of myb1 (chicken)
chr9_+_116263706 0.104 NM_130795
RGS3
regulator of G-protein signaling 3
chr22_+_35695792 0.095 NM_001135730
NM_001135732
NM_005488
TOM1


target of myb1 (chicken)


chr14_-_21572789 0.086 NM_001102454
ZNF219
zinc finger protein 219
chr8_+_97505876 0.084 NM_002998
SDC2
syndecan 2
chr14_-_21567069 0.082 NM_001101672
ZNF219
zinc finger protein 219
chr16_+_2205764 0.071 NM_032271
TRAF7
TNF receptor-associated factor 7
chr14_-_21566728 0.070 NM_016423
ZNF219
zinc finger protein 219
chr22_-_50746000 0.065 NM_012401
PLXNB2
plexin B2
chr9_+_139560193 0.056 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr9_+_139557378 0.053 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr2_-_227663454 0.040 NM_005544
IRS1
insulin receptor substrate 1
chr6_+_108882068 0.034 NM_001455
FOXO3
forkhead box O3
chr4_+_30721865 0.029 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr6_+_108881010 0.029 NM_201559
FOXO3
forkhead box O3
chr9_-_135819995 0.019 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr10_-_735522 0.018 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr16_-_87903028 0.015 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr5_+_43121641 0.014 NM_003432
ZNF131
zinc finger protein 131
chr15_+_85923739 0.013 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr9_-_138798957 0.012 NM_015447
CAMSAP1
calmodulin regulated spectrin-associated protein 1
chr1_+_15736387 0.011 NM_024329
EFHD2
EF-hand domain family, member D2
chr3_-_118959723 0.011 NM_003778
NM_212543
B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

chr14_-_39901619 0.005 NM_203301
FBXO33
F-box protein 33
chr4_-_36245893 0.005 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_-_12419702 0.004 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr5_-_32174397 0.003 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr15_+_38544966 0.002 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_-_63052884 0.002 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr17_-_1359410 0.001 NM_005206
NM_016823
CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.89 1.34e-04 GO:0009966 regulation of signal transduction
5.13 5.39e-04 GO:0023051 regulation of signaling
10.64 6.28e-04 GO:0043549 regulation of kinase activity
10.27 7.93e-04 GO:0051338 regulation of transferase activity
5.18 1.77e-03 GO:0065009 regulation of molecular function
4.45 2.18e-03 GO:0048583 regulation of response to stimulus
5.75 2.66e-03 GO:0050790 regulation of catalytic activity
10.62 3.88e-03 GO:0007243 intracellular protein kinase cascade
10.62 3.88e-03 GO:0023014 signal transduction via phosphorylation event
7.80 4.85e-03 GO:0042325 regulation of phosphorylation
7.58 5.86e-03 GO:0019220 regulation of phosphate metabolic process
7.58 5.86e-03 GO:0051174 regulation of phosphorus metabolic process
9.51 7.27e-03 GO:0045859 regulation of protein kinase activity
5.03 7.85e-03 GO:0035556 intracellular signal transduction
20.67 1.00e-02 GO:0008286 insulin receptor signaling pathway
2.93 2.26e-02 GO:0007165 signal transduction
15.93 2.76e-02 GO:0032869 cellular response to insulin stimulus
9.89 3.21e-02 GO:0051056 regulation of small GTPase mediated signal transduction
7.13 3.65e-02 GO:0001932 regulation of protein phosphorylation
28.99 3.96e-02 GO:0071901 negative regulation of protein serine/threonine kinase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
39.77 2.77e-03 GO:0005901 caveola
18.30 2.91e-03 GO:0045121 membrane raft
3.55 9.00e-03 GO:0005829 cytosol

Nothing significant found in function category.