• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: CRX.p2

Z-value: 0.918

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_102668892	1.648	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr4_+_81106423	1.309	NM_020226	PRDM8	PR domain containing 8
chr17_-_34207308	0.993	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr13_-_33760215	0.965	NM_001243466 NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr12_+_7942025	0.957		NANOG	Nanog homeobox
chr12_+_6881669	0.890	NM_002286	LAG3	lymphocyte-activation gene 3
chrM_-_9203	0.867
chr1_+_31883020	0.856	NM_001199037	SERINC2	serine incorporator 2
chr6_-_134496833	0.844		SGK1	serum/glucocorticoid regulated kinase 1
chr6_-_11779279	0.780	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr2_-_202563353	0.713	NM_033066	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr7_-_115670828	0.712	NM_001018058 NM_012252	TFEC	transcription factor EC
chrM_+_9217	0.687
chr9_-_35111534	0.678		FAM214B	family with sequence similarity 214, member B
chrM_+_8857	0.671
chrX_+_69454504	0.667	NM_001013579	AWAT1	acyl-CoA wax alcohol acyltransferase 1
chr6_-_132967141	0.642	NM_138327	TAAR1	trace amine associated receptor 1
chr16_-_48266181	0.621	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr7_-_115670774	0.614		TFEC	transcription factor EC
chr1_+_79086087	0.604	NM_006820	IFI44L	interferon-induced protein 44-like
chr15_-_90222572	0.577	NM_001145311 NM_002666	PLIN1	perilipin 1
chr11_-_1629614	0.567	NM_001012708	KRTAP5-3	keratin associated protein 5-3
chr12_-_56236614	0.565	NM_002429	MMP19	matrix metallopeptidase 19
chr17_-_39280377	0.553	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr7_+_99425635	0.537	NM_022820 NM_057095 NM_057096	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43
chr20_+_9288446	0.524	NM_000933	PLCB4	phospholipase C, beta 4
chrX_-_110655384	0.520	NM_178151 NM_001195553 NM_178152 NM_178153	DCX	doublecortin
chr10_+_114154522	0.505		ACSL5	acyl-CoA synthetase long-chain family member 5
chr5_+_135364583	0.493	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr17_-_39334439	0.492	NM_033062	KRTAP4-2	keratin associated protein 4-2
chrX_+_102585113	0.491	NM_152278	TCEAL7	transcription elongation factor A (SII)-like 7
chr2_-_26101301	0.491	NM_018263	ASXL2	additional sex combs like 2 (Drosophila)
chr6_+_32407618	0.482	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chrM_+_9182	0.478
chr9_-_74675498	0.468	NM_001128618	C9orf57	chromosome 9 open reading frame 57
chr13_-_34250899	0.461	NM_001243476	STARD13	StAR-related lipid transfer (START) domain containing 13
chr20_+_20037289	0.460	NM_001167816	C20orf26	chromosome 20 open reading frame 26
chr14_-_61748510	0.455	NM_001017970	TMEM30B	transmembrane protein 30B
chr9_+_12693385	0.443	NM_000550	TYRP1	tyrosinase-related protein 1
chr5_+_131409484	0.439	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr1_+_179560747	0.436	NM_001199091 NM_001199085 NM_173533	TDRD5	tudor domain containing 5
chr11_+_61717355	0.432	NM_001139443 NM_004183	BEST1	bestrophin 1
chr6_-_24877453	0.430	NM_015864	FAM65B	family with sequence similarity 65, member B
chr11_+_5410606	0.424	NM_001004756	OR51M1	olfactory receptor, family 51, subfamily M, member 1
chr8_+_32579350	0.421	NM_001159996	NRG1	neuregulin 1
chr15_-_40633122	0.420	NM_207380	C15orf52	chromosome 15 open reading frame 52
chr21_-_31869427	0.420	NM_181610	KRTAP19-4	keratin associated protein 19-4
chr15_-_99789585	0.419	NM_001040655 NM_001040656 NM_001040657 NM_001040658 NM_001040659 NM_001040660 NM_022905	TTC23	tetratricopeptide repeat domain 23
chr12_-_21487831	0.414	NM_021094	SLCO1A2	solute carrier organic anion transporter family, member 1A2
chr18_+_29769986	0.413	NM_005925	MEP1B	meprin A, beta
chr19_+_45174723	0.408	NM_001127893 NM_020219	CEACAM19	carcinoembryonic antigen-related cell adhesion molecule 19
chr3_+_160394946	0.391	NM_025047	ARL14	ADP-ribosylation factor-like 14
chr4_-_76957139	0.383	NM_005409	CXCL11	chemokine (C-X-C motif) ligand 11
chr3_+_97868169	0.380	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chrX_-_70331297	0.375	NM_000206	IL2RG	interleukin 2 receptor, gamma
chr20_-_49253425	0.375	NM_080829	FAM65C	family with sequence similarity 65, member C
chr20_-_62611308	0.367		SAMD10	sterile alpha motif domain containing 10
chr3_+_50306578	0.367		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr11_+_69467210	0.364		CCND1	cyclin D1
chr3_+_50306305	0.360		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_-_168513201	0.358	NM_003175	XCL1 XCL2	chemokine (C motif) ligand 1 chemokine (C motif) ligand 2
chr4_+_106631966	0.358	NM_001031720	GSTCD	glutathione S-transferase, C-terminal domain containing
chr1_-_173174611	0.351		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr1_+_20396652	0.349	NM_000929	PLA2G5	phospholipase A2, group V
chr1_+_155006281	0.349	NM_001143687 NM_152494	DCST1	DC-STAMP domain containing 1
chr12_+_7941994	0.346	NM_024865	NANOG	Nanog homeobox
chr11_-_102668822	0.344		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_131438451	0.339	NM_198827	GPR133	G protein-coupled receptor 133
chr6_+_7107799	0.337	NM_001168344	RREB1	ras responsive element binding protein 1
chr2_-_26101329	0.336		ASXL2	additional sex combs like 2 (Drosophila)
chr7_-_138363789	0.335	NM_001139456	SVOPL	SVOP-like
chr14_+_74035762	0.335	NM_006821	ACOT2	acyl-CoA thioesterase 2
chr18_+_616671	0.332	NM_199167	CLUL1	clusterin-like 1 (retinal)
chr10_+_124670216	0.331	NM_001029888	FAM24A	family with sequence similarity 24, member A
chr8_+_79428335	0.330	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr5_-_95768660	0.330	NM_000439	PCSK1	proprotein convertase subtilisin/kexin type 1
chr4_-_190948396	0.330	NM_001199232 NM_001005217	LOC100288255 FRG2	FSHD region gene 2-like FSHD region gene 2
chr1_-_156786500	0.329	NM_001161441 NM_001161442 NM_001161444 NM_003975	SH2D2A	SH2 domain containing 2A
chr17_-_39092714	0.329		KRT23	keratin 23 (histone deacetylase inducible)
chr11_-_102651321	0.328	NM_002425	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr1_-_27998700	0.326		IFI6	interferon, alpha-inducible protein 6
chr12_-_4488707	0.324	NM_020638	FGF23	fibroblast growth factor 23
chr9_+_125132823	0.319		PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_87755880	0.317	NM_019098	CNGB3	cyclic nucleotide gated channel beta 3
chr19_-_633526	0.316		POLRMT	polymerase (RNA) mitochondrial (DNA directed)
chr19_-_55668956	0.312	NM_000363	TNNI3	troponin I type 3 (cardiac)
chr2_-_100758970	0.310	NM_002285	AFF3	AF4/FMR2 family, member 3
chr12_-_52761254	0.309	NM_002283	KRT85	keratin 85
chr3_-_47621729	0.308	NM_001206942 NM_001206945	CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)
chrX_+_64708614	0.303	NM_001010888	ZC3H12B	zinc finger CCCH-type containing 12B
chr7_-_138482848	0.295	NM_020632 NM_130840	ATP6V0A4	ATPase, H+ transporting, lysosomal V0 subunit a4
chr6_+_43543877	0.294	NM_006502	POLH	polymerase (DNA directed), eta
chr3_-_147123306	0.293	NM_001168379	ZIC4	Zic family member 4
chr10_-_62149487	0.292	NM_020987	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_7818488	0.292	NM_153444	OR5P2	olfactory receptor, family 5, subfamily P, member 2
chr17_+_68100994	0.285	NM_170742	KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16
chr9_+_80911990	0.285	NM_021154 NM_058179	PSAT1	phosphoserine aminotransferase 1
chr11_+_60467046	0.279	NM_031457	MS4A8B	membrane-spanning 4-domains, subfamily A, member 8B
chr14_-_61748193	0.278
chr4_-_87028805	0.278	NM_138981	MAPK10	mitogen-activated protein kinase 10
chr5_-_169724614	0.277		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr20_-_44538654	0.276		PLTP	phospholipid transfer protein
chr6_+_43543921	0.276		POLH	polymerase (DNA directed), eta
chr11_+_118175294	0.275	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr15_-_31393906	0.273	NM_001252024 NM_001252030 NM_002420	TRPM1	transient receptor potential cation channel, subfamily M, member 1
chr11_-_116663106	0.273	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr12_+_7341758	0.272	NM_001131026	PEX5	peroxisomal biogenesis factor 5
chr6_-_111894897	0.272	NM_001164282	TRAF3IP2	TRAF3 interacting protein 2
chr18_+_8717368	0.271	NM_015210	CCDC165	coiled-coil domain containing 165
chr2_-_163099877	0.270	NM_004460	FAP	fibroblast activation protein, alpha
chr1_-_149908721	0.270		MTMR11	myotubularin related protein 11
chr12_-_2027802	0.266	NM_172364	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr17_-_7590731	0.265	NM_000546 NM_001126112 NM_001126113 NM_001126114	TP53	tumor protein p53
chrM_+_9725	0.264
chr12_-_8088629	0.263	NM_006931	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_15563160	0.262	NM_005677 NM_080539	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr2_-_31030271	0.262	NM_144575	CAPN13	calpain 13
chr1_-_149908759	0.259	NM_001145862	MTMR11	myotubularin related protein 11
chr14_+_23842017	0.259	NM_172314 NM_022789	IL25	interleukin 25
chr12_-_11175169	0.253	NM_176888	TAS2R19	taste receptor, type 2, member 19
chr21_-_35884503	0.253		KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr19_+_51645556	0.253	NM_014385 NM_016543	SIGLEC7	sialic acid binding Ig-like lectin 7
chr1_-_153067000	0.252	NM_001024209	SPRR2E	small proline-rich protein 2E
chr3_+_149192367	0.252	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr12_-_16758312	0.251	NM_001243611	LMO3	LIM domain only 3 (rhombotin-like 2)
chr7_+_26400503	0.251	NM_001199837	SNX10	sorting nexin 10
chr1_+_158979681	0.251	NM_001206567 NM_005531	IFI16	interferon, gamma-inducible protein 16
chr9_-_114090712	0.250	NM_205859	OR2K2	olfactory receptor, family 2, subfamily K, member 2
chr1_+_18957499	0.250	NM_001135254 NM_002584 NM_013945	PAX7	paired box 7
chr1_-_160617042	0.249	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr11_-_36619776	0.249	NM_000536 NM_001243785 NM_001243786	RAG2	recombination activating gene 2
chr12_-_16757944	0.249		LMO3	LIM domain only 3 (rhombotin-like 2)
chr2_-_111435604	0.248	NM_004336	BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)
chr4_-_40936640	0.244		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chrX_-_11284094	0.241	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr17_+_7210929	0.239		EIF5A	eukaryotic translation initiation factor 5A
chr14_+_88852065	0.237		SPATA7	spermatogenesis associated 7
chr8_+_86376130	0.237	NM_000067	CA2	carbonic anhydrase II
chr22_+_22676814	0.235
chr5_-_137071703	0.235	NM_017415	KLHL3	kelch-like 3 (Drosophila)
chr19_-_633563	0.234	NM_005035	POLRMT	polymerase (RNA) mitochondrial (DNA directed)
chr12_-_23737507	0.234	NM_178010	SOX5	SRY (sex determining region Y)-box 5
chr10_-_14372807	0.233	NM_018027	FRMD4A	FERM domain containing 4A
chr13_-_33780142	0.232	NM_001243474 NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr4_+_25658085	0.232	NM_001177999	SLC34A2	solute carrier family 34 (sodium phosphate), member 2
chr4_+_100432160	0.231	NM_032149	C4orf17	chromosome 4 open reading frame 17
chr14_-_73360792	0.231	NM_012074	DPF3	D4, zinc and double PHD fingers, family 3
chrX_-_24690740	0.231	NM_001163264	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr5_-_83680590	0.230	NM_005711	EDIL3	EGF-like repeats and discoidin I-like domains 3
chr12_+_6949374	0.230	NM_002075	GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3
chr14_-_71001731	0.230	NM_003814	ADAM20	ADAM metallopeptidase domain 20
chr16_-_69385656	0.229	NM_144676	TMED6	transmembrane emp24 protein transport domain containing 6
chr17_-_39254374	0.229	NM_031960	KRTAP4-8	keratin associated protein 4-8
chr3_+_88188261	0.227	NM_018293	ZNF654	zinc finger protein 654
chr12_-_53242716	0.227	NM_173352	KRT78	keratin 78
chr4_+_106067031	0.226	NM_017628	TET2	tet methylcytosine dioxygenase 2
chr1_+_150459913	0.224	NM_025150	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)
chr20_+_2903852	0.224	NM_080841	PTPRA	protein tyrosine phosphatase, receptor type, A
chr6_-_42690308	0.223	NM_000322	PRPH2	peripherin 2 (retinal degeneration, slow)
chr1_-_161601752	0.223	NM_000570	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr5_-_58652671	0.222	NM_001197219	PDE4D	phosphodiesterase 4D, cAMP-specific
chr16_+_67311412	0.221	NM_015432	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr2_-_37374948	0.221	NM_001135652	EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2
chr1_-_39347258	0.221	NM_030772	GJA9-MYCBP GJA9	GJA9-MYCBP readthrough gap junction protein, alpha 9, 59kDa
chr7_+_141463896	0.220	NM_016943	TAS2R3	taste receptor, type 2, member 3
chr16_+_81272293	0.220	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr6_-_52109226	0.219	NM_052872	IL17F	interleukin 17F
chr1_+_150459873	0.219		TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)
chr3_-_58563490	0.218	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr3_+_148447966	0.217	NM_032049	AGTR1	angiotensin II receptor, type 1
chr3_-_12941547	0.217		IQSEC1	IQ motif and Sec7 domain 1
chr6_+_52284948	0.217	NM_018100	EFHC1	EF-hand domain (C-terminal) containing 1
chr6_+_31554475	0.216	NM_205837	LST1	leukocyte specific transcript 1
chr10_+_91152321	0.215	NM_001548	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr3_-_19975671	0.215	NM_144715	EFHB	EF-hand domain family, member B
chr3_+_51989329	0.215	NM_080865	GPR62	G protein-coupled receptor 62
chr1_-_47655723	0.214	NM_005764	PDZK1IP1	PDZK1 interacting protein 1
chr12_-_11244828	0.214	NM_176884	TAS2R43 TAS2R31	taste receptor, type 2, member 43 taste receptor, type 2, member 31
chr12_+_49524648	0.213
chr15_-_72501017	0.213		PKM2	pyruvate kinase, muscle
chr12_-_53189780	0.212	NM_057088	KRT3	keratin 3
chr17_+_41158741	0.211	NM_005533	IFI35	interferon-induced protein 35
chr17_+_3118911	0.211	NM_014565	OR1A1	olfactory receptor, family 1, subfamily A, member 1
chr6_+_147527102	0.210		STXBP5	syntaxin binding protein 5 (tomosyn)
chr6_-_80247103	0.210	NM_001122769 NM_181714	LCA5	Leber congenital amaurosis 5
chr8_-_42234562	0.210	NM_014420	DKK4	dickkopf homolog 4 (Xenopus laevis)
chr19_-_39235113	0.210	NM_144691	CAPN12	calpain 12
chr20_+_31805118	0.209	NM_001042439 NM_178466	BPIFA3	BPI fold containing family A, member 3
chr2_+_3705785	0.209	NM_018436	ALLC	allantoicase
chr8_-_7220489	0.208	NM_001164457	ZNF705G	zinc finger protein 705G
chr1_-_158656487	0.208	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr20_-_20036685	0.208	NM_016652	CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr17_+_38465422	0.208	NM_000964	RARA	retinoic acid receptor, alpha
chr11_+_7618416	0.207		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_+_54415990	0.206	NM_031896	CACNG7	calcium channel, voltage-dependent, gamma subunit 7
chr12_-_111358353	0.206	NM_000432	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr12_+_20848288	0.206	NM_001145945 NM_001145946 NM_001145944 NM_017435	SLCO1C1	solute carrier organic anion transporter family, member 1C1
chr12_+_29376596	0.206	NM_018099	FAR2	fatty acyl CoA reductase 2
chr6_-_35480635	0.205	NM_003322	TULP1	tubby like protein 1
chr1_+_202509241	0.205	NM_001197131	PPP1R12B	protein phosphatase 1, regulatory subunit 12B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.53	1.10e-03	GO:0002376	immune system process
1.63	1.04e-02	GO:0006955	immune response
2.04	1.21e-02	GO:0050778	positive regulation of immune response
1.57	2.91e-02	GO:0006952	defense response
1.79	2.99e-02	GO:0002684	positive regulation of immune system process
1.77	4.01e-02	GO:0050776	regulation of immune response
10.49	4.78e-02	GO:0007210	serotonin receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.36	8.56e-04	GO:0005576	extracellular region

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.08	4.15e-02	GO:0005125	cytokine activity