Motif ID: CTCF.p2

Z-value: 1.061


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
CTCFchr16_+_675963090.232.7e-01Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_24772229 1.460 NEFM
neurofilament, medium polypeptide
chr16_-_2390711 1.413 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_37940180 1.350 ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_37940129 1.310 ZC3H12A
zinc finger CCCH-type containing 12A
chr2_+_233470766 1.200 NM_001243252
EFHD1
EF-hand domain family, member D1
chr16_-_2390593 1.171 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr10_-_79789290 1.164 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr16_-_2390737 1.134 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_37940074 1.126 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr22_+_31478845 0.900 NM_001207017
SMTN
smoothelin
chr19_-_1848359 0.876 REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr3_-_49967194 0.828 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr3_-_47517316 0.819 SCAP
SREBF chaperone
chr17_+_43213013 0.815 NM_001135705
NM_001135706
NM_001135707
NM_024722
ACBD4



acyl-CoA binding domain containing 4



chr3_-_47517417 0.806 NM_012235
SCAP
SREBF chaperone
chr16_+_230332 0.778 NM_005331
HBQ1
hemoglobin, theta 1
chr12_-_56583301 0.730 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr19_-_4400470 0.723 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr11_-_44972227 0.717 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr10_-_79789164 0.711 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr9_-_117160748 0.708 AKNA
AT-hook transcription factor
chr6_+_3849621 0.699 NM_012135
FAM50B
family with sequence similarity 50, member B
chr19_-_19754452 0.680 NM_016573
GMIP
GEM interacting protein
chr19_-_1848447 0.675 NM_020695
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr17_+_1958354 0.672 NM_006497
HIC1
hypermethylated in cancer 1
chr9_+_131798899 0.662 FAM73B
family with sequence similarity 73, member B
chr19_-_41859830 0.640 NM_000660
TGFB1
transforming growth factor, beta 1
chrX_+_47053302 0.637 UBA1
ubiquitin-like modifier activating enzyme 1
chr14_+_24630421 0.629 NM_006084
IRF9
interferon regulatory factor 9
chr17_-_73511626 0.608 NM_020753
CASKIN2
CASK interacting protein 2
chr19_+_12949258 0.604 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chrX_+_47053271 0.598 UBA1
ubiquitin-like modifier activating enzyme 1
chr17_-_73511453 0.598 CASKIN2
CASK interacting protein 2
chr6_-_119470336 0.592 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr19_+_38893828 0.579 FAM98C
family with sequence similarity 98, member C
chr10_+_112257624 0.575 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_+_38893804 0.572 FAM98C
family with sequence similarity 98, member C
chr6_+_138188352 0.566 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_-_19754369 0.564 GMIP
GEM interacting protein
chr20_+_37554954 0.563 NM_030919
FAM83D
family with sequence similarity 83, member D
chr11_+_117103237 0.563 NM_207343
NM_001077239
RNF214

ring finger protein 214

chr3_+_47866474 0.559 DHX30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr9_-_139258240 0.556 NM_001080849
DNLZ
DNL-type zinc finger
chr19_+_38893766 0.552 NM_174905
FAM98C
family with sequence similarity 98, member C
chr17_+_16593571 0.535 NM_014695
CCDC144B
CCDC144A
coiled-coil domain containing 144B (pseudogene)
coiled-coil domain containing 144A
chr11_+_2421983 0.528 TSSC4
tumor suppressing subtransferable candidate 4
chr9_+_131182690 0.526 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_40367539 0.525 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr19_+_42788605 0.519 NM_015125
CIC
capicua homolog (Drosophila)
chr12_+_7033625 0.510 NM_001007026
ATN1
atrophin 1
chrX_+_47053234 0.509 UBA1
ubiquitin-like modifier activating enzyme 1
chr19_-_2051222 0.504 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr20_+_36531548 0.503 VSTM2L
V-set and transmembrane domain containing 2 like
chr20_+_60877939 0.503 ADRM1
adhesion regulating molecule 1
chr10_+_102759232 0.495 LZTS2
leucine zipper, putative tumor suppressor 2
chr11_+_925795 0.492 NM_001242837
NM_012305
AP2A2

adaptor-related protein complex 2, alpha 2 subunit

chr22_+_22723972 0.485


chr11_+_46368881 0.478 NM_001199266
NM_001199267
NM_001199268
NM_003646
DGKZ



diacylglycerol kinase, zeta



chr7_-_27183225 0.478 NM_019102
HOXA5
homeobox A5
chr8_-_145550516 0.477 DGAT1
diacylglycerol O-acyltransferase 1
chr20_+_60878048 0.477 ADRM1
adhesion regulating molecule 1
chr12_+_49208615 0.474 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr19_-_49496566 0.473 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr20_+_60878024 0.471 NM_007002
NM_175573
ADRM1

adhesion regulating molecule 1

chr20_+_36531498 0.463 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr1_+_24645811 0.463 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr3_+_577913 0.458


chr10_+_116581495 0.456 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr15_+_75074714 0.450 CSK
c-src tyrosine kinase
chr11_+_925899 0.449 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr12_-_51663969 0.447 NM_001033873
NM_001031628
SMAGP

small cell adhesion glycoprotein

chr1_-_1624145 0.446 SLC35E2B
solute carrier family 35, member E2B
chr8_-_145550300 0.445 DGAT1
diacylglycerol O-acyltransferase 1
chr11_+_926021 0.444 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr9_-_136024522 0.443 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr15_+_75074417 0.441 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr19_-_49496520 0.441 GYS1
glycogen synthase 1 (muscle)
chrX_+_47053227 0.435 UBA1
ubiquitin-like modifier activating enzyme 1
chr5_-_69881965 0.435 SMA4
glucuronidase, beta pseudogene
chr16_+_2097985 0.433 NM_000548
NM_001077183
NM_001114382
TSC2


tuberous sclerosis 2


chr22_-_22307212 0.428 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr3_+_49208979 0.425 NM_173546
KLHDC8B
kelch domain containing 8B
chr19_-_49496369 0.422 GYS1
glycogen synthase 1 (muscle)
chr20_+_30028410 0.421 NM_153324
DEFB123
defensin, beta 123
chrX_+_47053213 0.421 UBA1
ubiquitin-like modifier activating enzyme 1
chr7_-_38375172 0.419 TRGV7
T cell receptor gamma variable 7 (pseudogene)
chr17_+_73996986 0.419 NM_001258
CDK3
cyclin-dependent kinase 3
chr5_+_69696805 0.417 SMA4
glucuronidase, beta pseudogene
chr11_+_925874 0.414 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr3_+_101568325 0.412 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chrX_+_153029578 0.408 NM_001163257
NM_005393
PLXNB3

plexin B3

chr16_-_790888 0.402 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr19_-_3028901 0.402 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_-_38746978 0.401 PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr9_-_134615216 0.399 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr9_+_131183122 0.398 CERCAM
cerebral endothelial cell adhesion molecule
chr18_+_596997 0.395 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr7_-_100425035 0.391 NM_004444
EPHB4
EPH receptor B4
chr7_-_100171269 0.390 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr9_-_139940595 0.386 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr9_+_34646600 0.385 GALT
galactose-1-phosphate uridylyltransferase
chr11_+_64018996 0.379 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr19_+_10982244 0.377 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1
chr19_-_4400357 0.376 NM_001199944
SH3GL1
SH3-domain GRB2-like 1
chr12_-_53715343 0.375 NM_001173466
NM_015665
AAAS

achalasia, adrenocortical insufficiency, alacrimia

chr13_-_53024730 0.371 NM_016075
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr13_+_31774087 0.371 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chr6_-_58287651 0.370 GUSBP4
glucuronidase, beta pseudogene 4
chr11_-_117102758 0.369 PCSK7
proprotein convertase subtilisin/kexin type 7
chr11_+_64018991 0.368 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr16_+_29827489 0.367 NM_024516
C16orf53
chromosome 16 open reading frame 53
chrX_+_47053192 0.365 NM_003334
UBA1
ubiquitin-like modifier activating enzyme 1
chr12_+_106751550 0.363 POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr8_-_146012653 0.360 NM_030580
ZNF34
zinc finger protein 34
chr5_-_139726173 0.360 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr13_+_31774122 0.358 B3GALTL
beta 1,3-galactosyltransferase-like
chr19_+_10982369 0.356 CARM1
coactivator-associated arginine methyltransferase 1
chr8_-_145634542 0.356 CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
chr11_+_125034604 0.355 PKNOX2
PBX/knotted 1 homeobox 2
chr9_+_131799212 0.349 NM_032809
FAM73B
family with sequence similarity 73, member B
chr1_+_20208837 0.349 NM_015207
OTUD3
OTU domain containing 3
chr2_-_74618978 0.347 DCTN1
dynactin 1
chr22_-_22307188 0.346 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr19_+_4791757 0.342 FEM1A
fem-1 homolog a (C. elegans)
chr15_-_40599872 0.341 PLCB2
phospholipase C, beta 2
chr22_-_50682915 0.340 TUBGCP6
tubulin, gamma complex associated protein 6
chr4_-_7044664 0.339 NM_153376
CCDC96
coiled-coil domain containing 96
chr1_+_10003485 0.339 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr19_+_4791756 0.337 FEM1A
fem-1 homolog a (C. elegans)
chr11_-_117102810 0.337 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr19_+_4791727 0.336 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr19_+_54041332 0.336 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr6_-_41006927 0.335 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr12_-_53715248 0.333 AAAS
achalasia, adrenocortical insufficiency, alacrimia
chr11_+_45826640 0.327 NM_018389
SLC35C1
solute carrier family 35, member C1
chr19_-_49540072 0.327 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr2_-_74618920 0.325 DCTN1
dynactin 1
chr19_-_38747171 0.325 NM_001243947
NM_033256
PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A

chr16_+_31484497 0.323 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr8_+_54764367 0.322 NM_170587
RGS20
regulator of G-protein signaling 20
chr11_+_125034558 0.321 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr2_-_86116016 0.321 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_20208908 0.321 OTUD3
OTU domain containing 3
chr10_-_101769640 0.319 NM_015221
DNMBP
dynamin binding protein
chr22_+_19705891 0.317 NM_001009939
SEPT5
septin 5
chr11_+_9779832 0.315 LOC283104
uncharacterized LOC283104
chr22_-_32598497 0.307 NM_001159546
RFPL2
ret finger protein-like 2
chr16_+_31724530 0.304 NM_001130913
ZNF720
zinc finger protein 720
chr8_+_145597747 0.301 ADCK5
aarF domain containing kinase 5
chr17_-_73267261 0.298 NM_001242498
NM_020679
MIF4GD

MIF4G domain containing

chr1_+_6640047 0.297 NM_005341
ZBTB48
zinc finger and BTB domain containing 48
chr9_-_117444368 0.296 NM_001199233
LOC100505478
uncharacterized LOC100505478
chr1_+_171283372 0.294 NM_002022
FMO4
flavin containing monooxygenase 4
chr16_-_2097818 0.293 NM_002528
NTHL1
nth endonuclease III-like 1 (E. coli)
chr16_+_29827707 0.293 C16orf53
chromosome 16 open reading frame 53
chr8_+_143808593 0.293 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr16_+_69345250 0.289 NM_013245
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr11_-_798196 0.289 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr5_+_148520985 0.288 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr6_-_34216824 0.287 NM_001008703
NM_001008704
NM_178508
C6orf1


chromosome 6 open reading frame 1


chr12_-_46384208 0.286 SCAF11
SR-related CTD-associated factor 11
chr11_-_8285299 0.286 NM_002315
LMO1
LIM domain only 1 (rhombotin 1)
chr17_+_48556180 0.285 NM_018346
RSAD1
radical S-adenosyl methionine domain containing 1
chr17_+_73585552 0.284 MYO15B
myosin XVB pseudogene
chr17_-_7518124 0.283 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr6_-_33547833 0.276 BAK1
BCL2-antagonist/killer 1
chr1_+_6640094 0.275 ZBTB48
zinc finger and BTB domain containing 48
chr17_+_48556217 0.274 RSAD1
radical S-adenosyl methionine domain containing 1
chr7_+_6629658 0.273 NM_024067
C7orf26
chromosome 7 open reading frame 26
chr22_+_19705990 0.273 SEPT5-GP1BB
SEPT5-GP1BB readthrough
chr3_+_31574119 0.271 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr12_+_106751435 0.271 NM_018082
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr9_-_35815040 0.267 NM_032593
HINT2
histidine triad nucleotide binding protein 2
chr3_-_38071030 0.267 NM_006225
PLCD1
phospholipase C, delta 1
chr19_+_5690307 0.267 RPL36
ribosomal protein L36
chr19_+_48216600 0.265 NM_014601
EHD2
EH-domain containing 2
chr5_+_53813494 0.264 NM_001145427
NM_001102575
NM_052870
SNX18


sorting nexin 18


chr17_-_48474864 0.264 LRRC59
leucine rich repeat containing 59
chr9_+_130965666 0.261 DNM1
dynamin 1
chr16_+_75032874 0.260 NM_032268
ZNRF1
zinc and ring finger 1
chrX_+_152110214 0.259 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr19_-_6279927 0.259 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr16_+_15737123 0.258 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr14_+_23305907 0.257 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr6_-_33267128 0.256 NM_001243738
NM_004761
RGL2

ral guanine nucleotide dissociation stimulator-like 2

chr1_+_110527327 0.255 NM_001242673
NM_006621
AHCYL1

adenosylhomocysteinase-like 1

chr17_-_61988614 0.255 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr19_-_6481765 0.255 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr7_-_92747317 0.254 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr19_+_18699494 0.254 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr12_-_120703549 0.253 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr17_+_38137088 0.252 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr17_-_7517849 0.251 FXR2
fragile X mental retardation, autosomal homolog 2
chr9_-_35814997 0.251 HINT2
histidine triad nucleotide binding protein 2
chrX_-_134953898 0.251 NM_001007551
NM_001172288
CT45A5

cancer/testis antigen family 45, member A5

chr8_-_145550536 0.251 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr13_-_113260728 0.249


chr18_-_57364572 0.249 CCBE1
collagen and calcium binding EGF domains 1
chr9_+_131464770 0.249 NM_013355
PKN3
protein kinase N3
chr11_+_107879609 0.247 CUL5
cullin 5

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 4.56e-02 GO:0005515 protein binding