• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: E2F1..5.p2

Z-value: 2.979

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_131762017	21.081	NM_001005463	EBF3	early B-cell factor 3
chr19_+_4909447	10.940	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr11_-_33890931	7.921		LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_-_33891361	6.662	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_-_33891258	6.049		LMO2	LIM domain only 2 (rhombotin-like 1)
chr8_-_124408458	5.681		ATAD2	ATPase family, AAA domain containing 2
chrX_+_101967290	5.672		GPRASP2	G protein-coupled receptor associated sorting protein 2
chr11_-_19262424	5.609	NM_024680	E2F8	E2F transcription factor 8
chr8_-_124408688	5.434	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr8_-_124408665	5.284		ATAD2	ATPase family, AAA domain containing 2
chr20_-_5100443	5.256	NM_182649	PCNA	proliferating cell nuclear antigen
chr3_-_148804122	5.159	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chrX_-_62974942	4.631		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_-_62974341	4.580		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr9_-_99180661	4.482	NM_153695	ZNF367	zinc finger protein 367
chr1_+_61547625	4.388	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr10_+_8096633	4.366	NM_001002295 NM_002051	GATA3	GATA binding protein 3
chr2_+_16080639	4.283	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_4910339	4.273	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chrX_-_62974987	4.246		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_-_52149541	4.211	NM_002388	MCM3	minichromosome maintenance complex component 3
chr1_+_228645807	4.206	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr2_-_136633934	4.174		MCM6	minichromosome maintenance complex component 6
chr15_-_71184611	4.150	NM_020147	THAP10	THAP domain containing 10
chr1_+_61542928	4.135	NM_001145511	NFIA	nuclear factor I/A
chr1_-_91487543	4.127		ZNF644	zinc finger protein 644
chr4_+_30721865	3.974	NM_032456 NM_001173523 NM_002589 NM_032457	PCDH7	protocadherin 7
chr6_-_52149516	3.908		MCM3	minichromosome maintenance complex component 3
chr11_-_19263144	3.845		E2F8	E2F transcription factor 8
chrX_+_24712063	3.806	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chrX_-_62975005	3.803	NM_001173480 NM_015185	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_+_127317271	3.794		MCM2	minichromosome maintenance complex component 2
chr3_+_127317212	3.710	NM_004526	MCM2	minichromosome maintenance complex component 2
chr3_+_127317274	3.691		MCM2	minichromosome maintenance complex component 2
chr6_-_52149472	3.690		MCM3	minichromosome maintenance complex component 3
chr7_-_27183225	3.664	NM_019102	HOXA5	homeobox A5
chr8_-_124408669	3.599		ATAD2	ATPase family, AAA domain containing 2
chr3_-_169381417	3.587	NM_001205194 NM_004991	MECOM	MDS1 and EVI1 complex locus
chr1_+_212208918	3.400	NM_016448	DTL	denticleless homolog (Drosophila)
chr12_-_56727720	3.348	NM_001166279 NM_014871	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_134514044	3.336	NM_004441	EPHB1	EPH receptor B1
chr4_+_126237566	3.330	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr15_+_66994669	3.318	NM_005585	SMAD6	SMAD family member 6
chrX_+_101967103	3.304	NM_001004051 NM_001184874 NM_001184875 NM_001184876 NM_138437	GPRASP2	G protein-coupled receptor associated sorting protein 2
chr16_+_67596309	3.282	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr22_+_35796104	3.248	NM_006739	MCM5	minichromosome maintenance complex component 5
chr1_+_212209129	3.183		DTL	denticleless homolog (Drosophila)
chr4_+_55523906	3.159	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr10_+_8096772	3.136		GATA3	GATA binding protein 3
chr12_-_56727446	3.099	NM_001127460	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_+_84743250	3.086	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr9_-_79520878	3.031	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr22_+_35796154	2.977		MCM5	minichromosome maintenance complex component 5
chr1_+_78511588	2.943	NM_017655	GIPC2	GIPC PDZ domain containing family, member 2
chr1_+_221052735	2.929	NM_021958	HLX	H2.0-like homeobox
chr9_+_504661	2.894	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr10_+_62538088	2.857	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr10_+_62538250	2.827		CDK1	cyclin-dependent kinase 1
chr17_-_46687925	2.810		HOXB7	homeobox B7
chr22_+_38201232	2.804		H1F0	H1 histone family, member 0
chr2_-_27485774	2.772	NM_003459	SLC30A3	solute carrier family 30 (zinc transporter), member 3
chr17_-_57184116	2.769		TRIM37	tripartite motif containing 37
chr6_-_144329342	2.767	NM_001080952 NM_001080953 NM_001080954 NM_001080956 NM_002656 NM_006718	PLAGL1 HYMAI	pleiomorphic adenoma gene-like 1 hydatidiform mole associated and imprinted (non-protein coding)
chr19_-_10305536	2.724		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr12_+_48499655	2.722	NM_001166686	PFKM	phosphofructokinase, muscle
chr12_+_109535922	2.713	NM_003362	UNG	uracil-DNA glycosylase
chr2_+_47630246	2.695	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr1_-_91487593	2.678		ZNF644	zinc finger protein 644
chr17_-_46688279	2.624		HOXB7	homeobox B7
chr17_+_38444134	2.618	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr12_+_109535377	2.598	NM_080911	UNG	uracil-DNA glycosylase
chr16_+_30406711	2.596	NM_152652	ZNF48	zinc finger protein 48
chr22_+_38201113	2.579	NM_005318	H1F0	H1 histone family, member 0
chr16_+_55542909	2.566	NM_017839	LPCAT2	lysophosphatidylcholine acyltransferase 2
chr2_+_12856813	2.547	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chrX_-_70473941	2.507		ZMYM3	zinc finger, MYM-type 3
chr19_-_10305600	2.492		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr16_+_72698996	2.473
chr1_+_221052845	2.466		HLX	H2.0-like homeobox
chr7_+_94139331	2.460		CASD1	CAS1 domain containing 1
chr2_-_164592512	2.436	NM_018086	FIGN	fidgetin
chr16_+_30406432	2.436	NM_001214909	ZNF48	zinc finger protein 48
chr22_+_35796294	2.427		MCM5	minichromosome maintenance complex component 5
chr14_-_74551159	2.421	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr2_+_10262853	2.416	NM_001034	RRM2	ribonucleotide reductase M2
chr14_-_74551073	2.411		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr18_-_46477080	2.399	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr2_+_10262694	2.370	NM_001165931	RRM2	ribonucleotide reductase M2
chr6_+_27833033	2.365	NM_003511	HIST1H2AI HIST1H2AL	histone cluster 1, H2ai histone cluster 1, H2al
chr11_-_77850687	2.362	NM_001007027 NM_024079	ALG8	asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr17_-_46688362	2.309	NM_004502	HOXB7	homeobox B7
chr1_+_212209112	2.280		DTL	denticleless homolog (Drosophila)
chrX_+_102000906	2.269	NM_001142529 NM_001142530	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr15_+_66995414	2.236		SMAD6	SMAD family member 6
chr11_+_65658101	2.194		CCDC85B	coiled-coil domain containing 85B
chr10_-_25241504	2.189	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr3_-_123167391	2.187	NM_183357	ADCY5	adenylate cyclase 5
chr2_+_47630291	2.177		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr17_+_38444151	2.175		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr7_-_148581379	2.174		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr1_+_46049659	2.171	NM_001195193 NM_002482 NM_152298	NASP	nuclear autoantigenic sperm protein (histone-binding)
chr13_-_110438896	2.083	NM_003749	IRS2	insulin receptor substrate 2
chr11_+_94822937	2.048	NM_015036	ENDOD1	endonuclease domain containing 1
chr5_+_36152142	2.045	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr10_+_13203547	2.042	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr11_+_9595309	2.033		WEE1	WEE1 homolog (S. pombe)
chr17_+_38444130	2.030		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr13_-_72441312	2.008	NM_004392 NM_080759 NM_080760	DACH1	dachshund homolog 1 (Drosophila)
chr19_-_10305645	2.004	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr5_-_79950348	2.001		DHFR	dihydrofolate reductase
chr4_+_134073180	1.996		PCDH10	protocadherin 10
chr2_+_47630190	1.988		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr9_-_35079520	1.981		FANCG	Fanconi anemia, complementation group G
chr13_+_34392254	1.977		RFC3	replication factor C (activator 1) 3, 38kDa
chr13_+_21277481	1.965	NM_138284	IL17D	interleukin 17D
chr5_-_107006585	1.943	NM_001962	EFNA5	ephrin-A5
chr17_+_65821625	1.936	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr2_-_136634002	1.933	NM_005915	MCM6	minichromosome maintenance complex component 6
chr14_-_50155097	1.930	NM_001197330 NM_001197331 NM_002692	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr14_-_50154920	1.911		POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr6_-_116575170	1.906	NM_021648	TSPYL4	TSPY-like 4
chr16_-_85722587	1.905	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr13_+_80055366	1.887		NDFIP2	Nedd4 family interacting protein 2
chr3_+_134514300	1.877		EPHB1	EPH receptor B1
chr12_-_31743822	1.865	NM_144973	DENND5B	DENN/MADD domain containing 5B
chr7_-_148581297	1.863		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr15_+_47476225	1.847	NM_001198999	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_-_57184114	1.842		TRIM37	tripartite motif containing 37
chr7_-_148581377	1.834		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr11_+_4115923	1.824	NM_001033	RRM1	ribonucleotide reductase M1
chr5_+_36152221	1.824		SKP2	S-phase kinase-associated protein 2 (p45)
chr16_-_47494753	1.821		ITFG1	integrin alpha FG-GAP repeat containing 1
chrX_+_153237990	1.810	NM_003492	TMEM187	transmembrane protein 187
chr17_+_58677603	1.804		PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_-_148581359	1.793		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr12_+_56522049	1.778		ESYT1	extended synaptotagmin-like protein 1
chr4_-_170679027	1.778	NM_017867	C4orf27	chromosome 4 open reading frame 27
chr7_-_148581403	1.769	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr13_+_114238978	1.761		TFDP1	transcription factor Dp-1
chr11_+_9595183	1.755	NM_003390	WEE1	WEE1 homolog (S. pombe)
chr4_-_146859960	1.748
chr16_-_47494981	1.738	NM_030790	ITFG1	integrin alpha FG-GAP repeat containing 1
chr7_+_94138991	1.738	NM_022900	CASD1	CAS1 domain containing 1
chr17_-_39684499	1.735		KRT19	keratin 19
chr11_+_47236492	1.732	NM_000107	DDB2	damage-specific DNA binding protein 2, 48kDa
chr13_+_80055494	1.731		NDFIP2	Nedd4 family interacting protein 2
chr6_+_24775640	1.725	NM_001251991	GMNN	geminin, DNA replication inhibitor
chr13_+_48877950	1.712		RB1	retinoblastoma 1
chr4_+_30722191	1.708		PCDH7	protocadherin 7
chr10_+_112327411	1.708	NM_005445	SMC3	structural maintenance of chromosomes 3
chr4_-_18023358	1.703	NM_001166139 NM_153686	LCORL	ligand dependent nuclear receptor corepressor-like
chr7_-_158497432	1.700	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr3_+_44803280	1.694		KIF15	kinesin family member 15
chr6_-_111804413	1.692	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr9_-_35079751	1.680	NM_004629	FANCG	Fanconi anemia, complementation group G
chr5_+_79950471	1.662		MSH3	mutS homolog 3 (E. coli)
chr13_+_80055257	1.656	NM_001161407 NM_019080	NDFIP2	Nedd4 family interacting protein 2
chr13_+_103249285	1.645	NM_003291	TPP2	tripeptidyl peptidase II
chr1_-_91487769	1.638	NM_032186 NM_201269	ZNF644	zinc finger protein 644
chr16_-_85722503	1.637		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr5_+_79950466	1.629		MSH3	mutS homolog 3 (E. coli)
chr1_-_221915426	1.624		DUSP10	dual specificity phosphatase 10
chr5_-_72861376	1.617	NM_023039	ANKRA2	ankyrin repeat, family A (RFXANK-like), 2
chr1_-_212208779	1.610	NM_001199809 NM_001199811 NM_001199812 NM_015434	INTS7	integrator complex subunit 7
chr5_-_79950783	1.595	NM_000791	DHFR	dihydrofolate reductase
chr12_+_56522043	1.591		ESYT1	extended synaptotagmin-like protein 1
chr6_+_72892371	1.587		RIMS1	regulating synaptic membrane exocytosis 1
chr3_+_111697827	1.575	NM_018394	ABHD10	abhydrolase domain containing 10
chr17_-_39684585	1.570	NM_002276	KRT19	keratin 19
chr1_+_221053000	1.556		HLX	H2.0-like homeobox
chr14_+_65879694	1.551		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr4_-_174450529	1.549		HAND2	heart and neural crest derivatives expressed 2
chr1_-_29449012	1.549	NM_001171868	TMEM200B	transmembrane protein 200B
chr13_-_41768533	1.546	NM_032138	KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr6_+_24775154	1.543	NM_001251989 NM_001251990 NM_015895	GMNN	geminin, DNA replication inhibitor
chr5_-_72861208	1.538		ANKRA2	ankyrin repeat, family A (RFXANK-like), 2
chr3_-_32022734	1.538		OSBPL10	oxysterol binding protein-like 10
chr12_+_56521953	1.519	NM_001184796 NM_015292	ESYT1	extended synaptotagmin-like protein 1
chr8_+_48873446	1.517		MCM4	minichromosome maintenance complex component 4
chr19_-_41859519	1.516		TGFB1	transforming growth factor, beta 1
chr20_+_25388328	1.509		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr22_-_29137776	1.508	NM_001005735 NM_007194 NM_145862	CHEK2	checkpoint kinase 2
chr19_-_45909566	1.502	NM_001142502	PPP1R13L	protein phosphatase 1, regulatory subunit 13 like
chr12_-_133263899	1.501	NM_006231	POLE	polymerase (DNA directed), epsilon
chr8_-_23021447	1.488	NM_003840	TNFRSF10D	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr11_+_9595451	1.483		WEE1	WEE1 homolog (S. pombe)
chr16_-_10674443	1.476	NM_001424	EMP2	epithelial membrane protein 2
chr15_-_41624760	1.473	NM_007280	OIP5	Opa interacting protein 5
chr11_+_4116059	1.465		RRM1	ribonucleotide reductase M1
chr2_+_189157551	1.464		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr2_-_136873740	1.456	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chr1_-_36235422	1.443	NM_001190481 NM_022111	CLSPN	claspin
chr1_-_11714471	1.438		FBXO2	F-box protein 2
chr11_-_33891485	1.434	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr5_-_79950307	1.433		DHFR	dihydrofolate reductase
chr20_+_25388320	1.430	NM_021067	GINS1	GINS complex subunit 1 (Psf1 homolog)
chr6_-_27782517	1.427	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr13_+_48878025	1.424		RB1	retinoblastoma 1
chrX_+_123095598	1.423		STAG2	stromal antigen 2
chr5_-_39074478	1.419		RICTOR	RPTOR independent companion of MTOR, complex 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.93	4.29e-27	GO:0090304	nucleic acid metabolic process
1.58	1.48e-26	GO:0044260	cellular macromolecule metabolic process
2.93	4.76e-25	GO:0051276	chromosome organization
2.96	1.96e-24	GO:0006259	DNA metabolic process
1.75	1.59e-23	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.38	1.61e-23	GO:0007049	cell cycle
2.62	4.24e-20	GO:0022403	cell cycle phase
1.46	1.49e-19	GO:0043170	macromolecule metabolic process
2.39	5.09e-18	GO:0022402	cell cycle process
1.57	8.76e-17	GO:0006807	nitrogen compound metabolic process
1.35	9.26e-17	GO:0044237	cellular metabolic process
1.58	1.05e-16	GO:0034641	cellular nitrogen compound metabolic process
4.03	8.17e-16	GO:0006260	DNA replication
2.56	1.92e-15	GO:0000278	mitotic cell cycle
2.73	5.05e-15	GO:0006325	chromatin organization
3.01	2.69e-14	GO:0006281	DNA repair
1.32	4.24e-14	GO:0044238	primary metabolic process
1.79	3.81e-13	GO:0006996	organelle organization
2.43	1.89e-11	GO:0006974	response to DNA damage stimulus
1.27	2.02e-11	GO:0008152	metabolic process
2.89	4.46e-11	GO:0051325	interphase
3.78	5.31e-11	GO:0071103	DNA conformation change
2.54	7.52e-11	GO:0000279	M phase
3.98	1.44e-10	GO:0006323	DNA packaging
1.15	1.82e-10	GO:0009987	cellular process
2.84	2.42e-10	GO:0051329	interphase of mitotic cell cycle
1.67	5.92e-10	GO:0016070	RNA metabolic process
1.43	1.27e-09	GO:0016043	cellular component organization
1.51	1.37e-09	GO:0071842	cellular component organization at cellular level
1.67	1.54e-09	GO:0034645	cellular macromolecule biosynthetic process
1.49	1.98e-09	GO:0071841	cellular component organization or biogenesis at cellular level
2.58	2.77e-09	GO:0016568	chromatin modification
2.16	2.99e-09	GO:0051726	regulation of cell cycle
2.60	4.26e-09	GO:0010564	regulation of cell cycle process
1.41	4.52e-09	GO:0071840	cellular component organization or biogenesis
1.65	4.63e-09	GO:0009059	macromolecule biosynthetic process
1.52	6.73e-09	GO:0044249	cellular biosynthetic process
4.05	1.91e-08	GO:0034728	nucleosome organization
4.12	2.53e-08	GO:0031497	chromatin assembly
3.55	2.87e-08	GO:0006333	chromatin assembly or disassembly
4.75	3.88e-08	GO:0006261	DNA-dependent DNA replication
1.48	4.67e-08	GO:0009058	biosynthetic process
3.80	5.51e-08	GO:0071824	protein-DNA complex subunit organization
3.89	5.82e-08	GO:0065004	protein-DNA complex assembly
3.45	7.21e-08	GO:0000082	G1/S transition of mitotic cell cycle
1.57	1.13e-07	GO:0010467	gene expression
2.16	1.41e-07	GO:0016071	mRNA metabolic process
4.05	1.90e-07	GO:0006334	nucleosome assembly
1.88	3.89e-07	GO:0033554	cellular response to stress
3.35	5.79e-07	GO:0006310	DNA recombination
3.63	8.19e-07	GO:0051320	S phase
11.09	8.27e-07	GO:0071897	DNA biosynthetic process
2.54	9.34e-07	GO:0000280	nuclear division
2.54	9.34e-07	GO:0007067	mitosis
3.57	2.41e-06	GO:0000084	S phase of mitotic cell cycle
2.46	2.72e-06	GO:0000087	M phase of mitotic cell cycle
2.27	3.03e-06	GO:0006397	mRNA processing
2.45	3.10e-06	GO:0048285	organelle fission
1.94	5.10e-06	GO:0006396	RNA processing
6.65	6.52e-06	GO:0006271	DNA strand elongation involved in DNA replication
6.21	2.05e-05	GO:0022616	DNA strand elongation
7.26	2.55e-05	GO:0006270	DNA-dependent DNA replication initiation
3.36	7.16e-05	GO:0007059	chromosome segregation
1.33	8.17e-05	GO:0060255	regulation of macromolecule metabolic process
7.32	9.57e-05	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
7.32	9.57e-05	GO:0006298	mismatch repair
1.99	1.18e-04	GO:0034621	cellular macromolecular complex subunit organization
2.54	1.33e-04	GO:0000075	cell cycle checkpoint
1.30	1.92e-04	GO:0031323	regulation of cellular metabolic process
2.16	2.07e-04	GO:0051301	cell division
2.13	2.31e-04	GO:0034622	cellular macromolecular complex assembly
1.30	3.20e-04	GO:0080090	regulation of primary metabolic process
4.13	3.34e-04	GO:0016573	histone acetylation
7.39	3.60e-04	GO:0007062	sister chromatid cohesion
2.45	3.87e-04	GO:0071156	regulation of cell cycle arrest
1.37	4.20e-04	GO:0044267	cellular protein metabolic process
4.06	4.47e-04	GO:0018393	internal peptidyl-lysine acetylation
1.61	4.47e-04	GO:0022607	cellular component assembly
3.99	5.94e-04	GO:0018394	peptidyl-lysine acetylation
2.20	5.97e-04	GO:0008380	RNA splicing
1.69	5.98e-04	GO:0043933	macromolecular complex subunit organization
1.56	6.67e-04	GO:0044085	cellular component biogenesis
1.36	6.92e-04	GO:0010468	regulation of gene expression
3.93	7.84e-04	GO:0006475	internal protein amino acid acetylation
4.54	9.43e-04	GO:0000819	sister chromatid segregation
3.72	9.53e-04	GO:0006473	protein acetylation
3.05	9.74e-04	GO:0007126	meiosis
3.05	9.74e-04	GO:0051327	M phase of meiotic cell cycle
1.74	1.08e-03	GO:0065003	macromolecular complex assembly
10.35	1.09e-03	GO:0002566	somatic diversification of immune receptors via somatic mutation
10.35	1.09e-03	GO:0016446	somatic hypermutation of immunoglobulin genes
2.57	1.11e-03	GO:0016569	covalent chromatin modification
3.03	1.17e-03	GO:0051321	meiotic cell cycle
1.71	1.19e-03	GO:0071844	cellular component assembly at cellular level
3.80	1.34e-03	GO:0031124	mRNA 3'-end processing
4.18	1.41e-03	GO:0051053	negative regulation of DNA metabolic process
1.26	1.70e-03	GO:0019222	regulation of metabolic process
1.36	1.77e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
5.86	1.79e-03	GO:0002200	somatic diversification of immune receptors
2.54	2.25e-03	GO:0016570	histone modification
4.54	2.26e-03	GO:0000070	mitotic sister chromatid segregation
6.34	2.35e-03	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
6.34	2.35e-03	GO:0016444	somatic cell DNA recombination
1.33	2.98e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	3.18e-03	GO:0051171	regulation of nitrogen compound metabolic process
4.07	4.52e-03	GO:0007051	spindle organization
1.33	5.67e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.35	6.62e-03	GO:0000375	RNA splicing, via transesterification reactions
1.38	8.29e-03	GO:0043412	macromolecule modification
1.31	9.20e-03	GO:0031326	regulation of cellular biosynthetic process
1.34	9.40e-03	GO:0051252	regulation of RNA metabolic process
2.34	1.00e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.34	1.00e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
2.54	1.07e-02	GO:0000226	microtubule cytoskeleton organization
9.98	1.13e-02	GO:0000731	DNA synthesis involved in DNA repair
9.98	1.13e-02	GO:0007064	mitotic sister chromatid cohesion
3.20	1.14e-02	GO:0018205	peptidyl-lysine modification
3.20	1.14e-02	GO:0043543	protein acylation
1.55	1.33e-02	GO:0032774	RNA biosynthetic process
3.28	1.38e-02	GO:0006338	chromatin remodeling
1.38	1.41e-02	GO:0006464	protein modification process
1.30	1.46e-02	GO:0009889	regulation of biosynthetic process
1.71	1.50e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.88	1.54e-02	GO:0007131	reciprocal meiotic recombination
3.19	2.08e-02	GO:0031123	RNA 3'-end processing
1.69	2.32e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.53	2.75e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
3.57	2.83e-02	GO:0007127	meiosis I
6.26	3.40e-02	GO:0016447	somatic recombination of immunoglobulin gene segments
1.15	3.57e-02	GO:0050794	regulation of cellular process
1.54	3.66e-02	GO:0010605	negative regulation of macromolecule metabolic process
3.07	3.73e-02	GO:0000216	M/G1 transition of mitotic cell cycle
1.52	3.84e-02	GO:0009892	negative regulation of metabolic process
1.55	3.90e-02	GO:0006351	transcription, DNA-dependent
5.44	3.91e-02	GO:0016445	somatic diversification of immunoglobulins

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.57	4.51e-39	GO:0005634	nucleus
2.08	3.62e-37	GO:0044428	nuclear part
1.30	8.92e-33	GO:0043226	organelle
1.30	1.75e-32	GO:0043229	intracellular organelle
2.11	2.05e-32	GO:0031981	nuclear lumen
1.33	3.87e-32	GO:0043227	membrane-bounded organelle
1.33	4.99e-32	GO:0043231	intracellular membrane-bounded organelle
1.23	2.52e-31	GO:0044424	intracellular part
1.22	6.23e-30	GO:0005622	intracellular
1.90	7.83e-28	GO:0070013	intracellular organelle lumen
1.88	2.17e-27	GO:0043233	organelle lumen
2.23	4.31e-27	GO:0005654	nucleoplasm
1.86	1.75e-26	GO:0031974	membrane-enclosed lumen
1.45	2.88e-24	GO:0044446	intracellular organelle part
1.44	1.16e-23	GO:0044422	organelle part
2.72	1.98e-19	GO:0005694	chromosome
2.64	1.24e-14	GO:0044427	chromosomal part
2.12	1.66e-11	GO:0044451	nucleoplasm part
3.01	1.71e-10	GO:0000785	chromatin
1.48	3.63e-10	GO:0043228	non-membrane-bounded organelle
1.48	3.63e-10	GO:0043232	intracellular non-membrane-bounded organelle
1.40	1.21e-09	GO:0032991	macromolecular complex
2.92	1.24e-08	GO:0000228	nuclear chromosome
2.74	1.53e-05	GO:0044454	nuclear chromosome part
1.06	1.89e-05	GO:0044464	cell part
1.06	1.96e-05	GO:0005623	cell
8.87	1.59e-04	GO:0032300	mismatch repair complex
10.35	1.78e-04	GO:0035098	ESC/E(Z) complex
1.31	2.80e-04	GO:0043234	protein complex
2.05	3.60e-04	GO:0005815	microtubule organizing center
1.82	4.76e-04	GO:0030529	ribonucleoprotein complex
3.77	5.14e-04	GO:0000123	histone acetyltransferase complex
2.25	1.12e-03	GO:0005813	centrosome
2.25	1.12e-03	GO:0016604	nuclear body
6.30	1.46e-03	GO:0031519	PcG protein complex
9.98	1.85e-03	GO:0042555	MCM complex
2.94	2.50e-03	GO:0032993	protein-DNA complex
3.08	3.33e-03	GO:0000790	nuclear chromatin
2.49	5.34e-03	GO:0000793	condensed chromosome
2.44	7.91e-03	GO:0000775	chromosome, centromeric region
3.96	2.42e-02	GO:0005657	replication fork
3.63	2.87e-02	GO:0000792	heterochromatin
1.64	4.57e-02	GO:0005730	nucleolus
3.26	4.78e-02	GO:0034708	methyltransferase complex
3.26	4.78e-02	GO:0035097	histone methyltransferase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.55	1.64e-17	GO:0003676	nucleic acid binding
1.60	6.59e-13	GO:0003677	DNA binding
1.13	6.26e-10	GO:0005488	binding
1.23	1.89e-09	GO:0005515	protein binding
8.56	6.32e-05	GO:0030983	mismatched DNA binding
2.58	7.22e-05	GO:0003682	chromatin binding
5.51	2.88e-04	GO:0034061	DNA polymerase activity
2.45	5.66e-04	GO:0043566	structure-specific DNA binding
5.63	6.67e-04	GO:0003887	DNA-directed DNA polymerase activity
1.94	1.48e-03	GO:0003712	transcription cofactor activity
1.93	1.60e-03	GO:0000988	protein binding transcription factor activity
1.93	1.60e-03	GO:0000989	transcription factor binding transcription factor activity
11.09	8.04e-03	GO:0032135	DNA insertion or deletion binding
1.56	8.89e-03	GO:0003723	RNA binding
2.47	1.32e-02	GO:0003690	double-stranded DNA binding
3.06	1.58e-02	GO:0042393	histone binding
1.56	1.86e-02	GO:0019899	enzyme binding
13.31	1.91e-02	GO:0032138	single base insertion or deletion binding
3.60	2.21e-02	GO:0003684	damaged DNA binding
9.51	2.64e-02	GO:0032404	mismatch repair complex binding
3.27	3.66e-02	GO:0003697	single-stranded DNA binding