Motif ID: EBF1.p2

Z-value: 1.382


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
EBF1chr5_-_1585264280.213.2e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_57406398 5.074 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr19_+_10381763 3.251 ICAM1
intercellular adhesion molecule 1
chr9_-_136344182 3.220 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr14_-_51135021 2.807 NM_021818
SAV1
salvador homolog 1 (Drosophila)
chr19_+_10381516 2.705 NM_000201
ICAM1
intercellular adhesion molecule 1
chr15_+_67358194 2.547 NM_005902
SMAD3
SMAD family member 3
chr4_+_4861371 2.392 NM_002448
MSX1
msh homeobox 1
chr15_+_67418053 2.333 NM_001145102
SMAD3
SMAD family member 3
chr8_-_48650683 2.253 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr6_-_31550065 2.238 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr8_+_90770201 2.158 RIPK2
receptor-interacting serine-threonine kinase 2
chr2_+_228678556 2.146 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr19_+_676346 2.074 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr4_-_74964996 2.063 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr15_+_62359175 1.838 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr19_+_4229494 1.769 NM_005755
EBI3
Epstein-Barr virus induced 3
chr5_-_150467220 1.722 NM_001252390
TNIP1
TNFAIP3 interacting protein 1
chr15_+_67458492 1.694 NM_001145104
SMAD3
SMAD family member 3
chr17_-_73874634 1.666 NM_033452
TRIM47
tripartite motif containing 47
chr14_-_51134862 1.658 SAV1
salvador homolog 1 (Drosophila)
chr3_+_10206562 1.629 NM_001570
IRAK2
interleukin-1 receptor-associated kinase 2
chr5_-_150466696 1.622 NM_001252391
NM_001252392
TNIP1

TNFAIP3 interacting protein 1

chr11_-_128392061 1.598 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr14_-_51135041 1.578 SAV1
salvador homolog 1 (Drosophila)
chr8_+_142138684 1.566 NM_014957
DENND3
DENN/MADD domain containing 3
chr3_+_122399665 1.543 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr4_+_103422553 1.456 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr2_+_237478379 1.439 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr21_+_26934440 1.437 MIR155HG
MIR155 host gene (non-protein coding)
chr2_+_231578262 1.376 NM_001130849
NM_001130850
CAB39

calcium binding protein 39

chr14_+_103589711 1.351 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr4_-_74904329 1.340 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr6_-_10419786 1.338 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_4890225 1.330 NM_001143971
CDYL
chromodomain protein, Y-like
chr8_+_17354562 1.323 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr21_-_37914897 1.279 NM_001146078
CLDN14
claudin 14
chr11_-_72504643 1.275 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_-_43596919 1.238 NM_019096
GTPBP2
GTP binding protein 2
chr6_-_43596764 1.224 GTPBP2
GTP binding protein 2
chr8_-_48650703 1.219 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_-_53499055 1.200 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr16_+_86544104 1.190 NM_001451
FOXF1
forkhead box F1
chr18_+_55711890 1.155 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_-_681222 1.143 NM_207332
ERICH1
glutamate-rich 1
chr11_-_128391888 1.139 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_125800786 1.118 NM_001146322
GRAMD3
GRAM domain containing 3
chr4_-_74964836 1.107 CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_158438079 1.088 NM_001178088
SYNJ2
synaptojanin 2
chr1_+_212788359 1.081 NM_001206486
ATF3
activating transcription factor 3
chr15_-_62457481 1.060 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr16_+_3115641 1.050 NM_001012632
NM_001012636
IL32

interleukin 32

chr10_-_135171512 1.046 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr1_-_95007139 1.035 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr22_-_43116796 1.029 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chr7_-_98467483 1.021 TMEM130
transmembrane protein 130
chr17_+_74380943 1.018 SPHK1
sphingosine kinase 1
chr6_-_167275657 0.999 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_+_49376488 0.982 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr10_+_102107256 0.975


chr6_+_4836331 0.965 NM_001143970
CDYL
chromodomain protein, Y-like
chr14_-_73493744 0.937 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr22_+_37309618 0.920 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr19_-_50432952 0.913 NM_016553
NUP62
nucleoporin 62kDa
chr12_-_57504088 0.904 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_-_167275997 0.895 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_145582111 0.884 NM_012162
NM_024555
FBXL6

F-box and leucine-rich repeat protein 6

chr14_-_52535737 0.882 NID2
nidogen 2 (osteonidogen)
chr19_-_49658645 0.881 NM_002152
HRC
histidine rich calcium binding protein
chr18_+_55711746 0.877 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_55711388 0.876 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr9_+_116930778 0.873 COL27A1
collagen, type XXVII, alpha 1
chr16_-_67867798 0.855 CENPT
centromere protein T
chr14_+_59655351 0.848 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr16_-_67867736 0.846 CENPT
centromere protein T
chr19_-_47734215 0.845 NM_014417
BBC3
BCL2 binding component 3
chr1_-_21605984 0.842 NM_001113347
ECE1
endothelin converting enzyme 1
chr21_+_44073650 0.830 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr9_-_123689172 0.806 NM_005658
TRAF1
TNF receptor-associated factor 1
chr21_-_35899046 0.805 NM_203418
RCAN1
regulator of calcineurin 1
chr4_-_7436614 0.796 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr12_-_111021026 0.794 NM_139283
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr5_-_95297597 0.794 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr19_+_39903749 0.789 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr10_-_60027630 0.776 NM_152230
IPMK
inositol polyphosphate multikinase
chr20_+_327329 0.767 NM_024958
NRSN2
neurensin 2
chr8_+_22298331 0.751 NM_001243974
NM_001243975
NM_005605
PPP3CC


protein phosphatase 3, catalytic subunit, gamma isozyme


chr19_+_3185927 0.743 NCLN
nicalin
chr15_-_79237353 0.739 NM_004390
CTSH
cathepsin H
chr9_-_134615216 0.738 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr14_-_52535765 0.734 NID2
nidogen 2 (osteonidogen)
chr11_-_117747618 0.730 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr12_-_111021122 0.730 PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr8_+_22298767 0.728 PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr12_+_121647936 0.726 P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr8_+_42128821 0.721 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr16_-_67867799 0.720 CENPT
centromere protein T
chr19_+_3185965 0.717 NCLN
nicalin
chr8_+_22298587 0.707 PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr11_+_73087396 0.705 NM_152222
RELT
RELT tumor necrosis factor receptor
chr6_+_135502521 0.702 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_-_79237320 0.701 CTSH
cathepsin H
chr5_+_140734767 0.696 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr1_-_12677347 0.693 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_-_33336289 0.690 NM_001171940
NM_153756
FNDC5

fibronectin type III domain containing 5

chr3_-_37217716 0.684 NM_001134369
NM_006309
NM_017724
LRRFIP2


leucine rich repeat (in FLII) interacting protein 2


chr11_-_117747331 0.684 FXYD6
FXYD domain containing ion transport regulator 6
chr8_-_33424642 0.680 NM_024787
RNF122
ring finger protein 122
chr17_-_76778306 0.676 NM_004762
NM_017456
CYTH1

cytohesin 1

chr16_-_67867809 0.676 CENPT
centromere protein T
chr15_+_81293286 0.665 NM_022566
MESDC1
mesoderm development candidate 1
chr16_-_75529278 0.665


chrX_+_9432980 0.664 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr8_+_145582208 0.664 NM_001253816
NM_001253815
GPR172A

G protein-coupled receptor 172A

chr16_+_2039945 0.662 NM_004209
SYNGR3
synaptogyrin 3
chr2_-_239140214 0.660 LOC151174
uncharacterized LOC151174
chr15_-_38856830 0.659 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr22_+_45705965 0.654 FAM118A
family with sequence similarity 118, member A
chr11_+_8932700 0.653 NM_001206646
NM_001206647
NM_001206648
NM_020642
AKIP1



A kinase (PRKA) interacting protein 1



chr15_+_63414037 0.650 LACTB
lactamase, beta
chr17_+_77020229 0.650 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr14_-_52535711 0.645 NID2
nidogen 2 (osteonidogen)
chr4_+_4388804 0.644 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr1_-_231004050 0.643 C1orf198
chromosome 1 open reading frame 198
chr9_+_116356407 0.640 RGS3
regulator of G-protein signaling 3
chr17_+_77020278 0.639 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_+_67573746 0.637 FAM65A
family with sequence similarity 65, member A
chr5_+_179234002 0.636 NM_001142299
SQSTM1
sequestosome 1
chr14_-_55369163 0.628 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr1_-_111148974 0.621 NM_004974
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr11_+_722282 0.618 EPS8L2
EPS8-like 2
chr4_-_4291731 0.615 NM_001145725
LYAR
Ly1 antibody reactive homolog (mouse)
chr11_+_73359734 0.613 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr5_-_141257943 0.613 NM_002587
NM_032420
PCDH1

protocadherin 1

chr10_-_104001229 0.612 NM_005029
PITX3
paired-like homeodomain 3
chr15_-_64338519 0.611 NM_014326
DAPK2
death-associated protein kinase 2
chr10_+_75670915 0.605 PLAU
plasminogen activator, urokinase
chr1_+_8384389 0.605 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr16_+_25703346 0.602 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr3_+_73045939 0.599 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr1_-_21616888 0.595 NM_001397
ECE1
endothelin converting enzyme 1
chr16_+_4385141 0.592 GLIS2
GLIS family zinc finger 2
chr2_-_120281801 0.586 SCTR
secretin receptor
chr14_+_73704204 0.584 NM_173462
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr9_-_95896498 0.581 NM_004148
NINJ1
ninjurin 1
chr16_+_68679229 0.577 CDH3
cadherin 3, type 1, P-cadherin (placental)
chrX_+_48336379 0.574 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr17_-_67323185 0.562 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr6_+_14117857 0.562 NM_001040280
NM_004233
CD83

CD83 molecule

chr19_+_55591759 0.562 NM_017729
EPS8L1
EPS8-like 1
chr14_-_52535945 0.561 NM_007361
NID2
nidogen 2 (osteonidogen)
chr4_-_2965036 0.558 NOP14
NOP14 nucleolar protein homolog (yeast)
chr5_+_10564431 0.558 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr1_+_206643786 0.557 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr8_-_101322245 0.557 NM_183419
RNF19A
ring finger protein 19A
chr2_-_120282012 0.555 NM_002980
SCTR
secretin receptor
chr15_+_41625152 0.554 NUSAP1
nucleolar and spindle associated protein 1
chr16_-_67977956 0.552 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr4_+_128982483 0.550 LARP1B
La ribonucleoprotein domain family, member 1B
chr3_-_11761946 0.544 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr1_+_6094342 0.542 NM_001199860
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_+_42128834 0.535 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr17_+_15848230 0.534 NM_000676
ADORA2B
adenosine A2b receptor
chr11_+_73087670 0.533 NM_032871
RELT
RELT tumor necrosis factor receptor
chr19_+_36132646 0.532 NM_014209
ETV2
ets variant 2
chr11_+_93862060 0.532 NM_015368
PANX1
pannexin 1
chr1_+_156339002 0.530 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr22_-_36635552 0.529 APOL2
apolipoprotein L, 2
chr19_-_10679328 0.527 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr10_-_121632265 0.527 NM_024834
MCMBP
minichromosome maintenance complex binding protein
chr19_+_7702020 0.527 STXBP2
syntaxin binding protein 2
chr9_-_133814422 0.524 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr3_-_48229328 0.522 CDC25A
cell division cycle 25 homolog A (S. pombe)
chr8_+_104310660 0.521 NM_001164615
FZD6
frizzled family receptor 6
chr13_+_24734788 0.520 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr6_+_1390068 0.518 NM_001452
FOXF2
forkhead box F2
chr16_+_67562704 0.515 NM_024519
NM_001193522
FAM65A

family with sequence similarity 65, member A

chr21_+_43619798 0.514 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr14_-_94844881 0.514 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr12_-_57472547 0.513 TMEM194A
transmembrane protein 194A
chr15_+_63413998 0.510 NM_032857
NM_171846
LACTB

lactamase, beta

chr2_-_120282060 0.509 SCTR
secretin receptor
chr12_+_64238511 0.509 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr17_+_7255207 0.506 NM_001002914
KCTD11
potassium channel tetramerisation domain containing 11
chr8_+_141521365 0.503 NM_017444
CHRAC1
chromatin accessibility complex 1
chr1_-_231004173 0.500 NM_032800
C1orf198
chromosome 1 open reading frame 198
chr8_-_101322180 0.500 RNF19A
ring finger protein 19A
chr11_-_2019070 0.500 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr12_+_112563359 0.500 TRAFD1
TRAF-type zinc finger domain containing 1
chr2_+_231577624 0.499 CAB39
calcium binding protein 39
chr2_+_109745996 0.499 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr12_-_57472573 0.491 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr5_+_121647385 0.491 SNCAIP
synuclein, alpha interacting protein
chr12_+_112563293 0.490 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr5_-_32444729 0.489 ZFR
zinc finger RNA binding protein
chr4_-_141489882 0.486 NM_021833
UCP1
uncoupling protein 1 (mitochondrial, proton carrier)
chr1_+_206643830 0.486 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr8_-_99306563 0.485 NM_024759
NIPAL2
NIPA-like domain containing 2
chr16_+_56672577 0.484 NM_005946
MT1A
metallothionein 1A
chr10_+_6244839 0.483 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_57472487 0.482 TMEM194A
transmembrane protein 194A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 5.59e-04 GO:0065007 biological regulation
1.13 1.21e-03 GO:0050789 regulation of biological process
1.13 2.04e-03 GO:0050794 regulation of cellular process
1.08 2.49e-03 GO:0009987 cellular process
1.20 5.41e-03 GO:0023052 signaling
1.32 8.75e-03 GO:0023051 regulation of signaling
1.21 1.08e-02 GO:0007165 signal transduction
1.34 1.13e-02 GO:0009966 regulation of signal transduction
1.27 4.26e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 7.28e-06 GO:0005737 cytoplasm
1.12 1.17e-02 GO:0044444 cytoplasmic part
1.24 1.60e-02 GO:0005829 cytosol
1.23 2.53e-02 GO:0044459 plasma membrane part
1.06 4.03e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 1.15e-07 GO:0005515 protein binding
1.07 8.58e-04 GO:0005488 binding