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Motif ID: EP300.p2

Z-value: 0.735

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_95007139	1.489	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr5_-_131826426	0.814	NM_002198	IRF1	interferon regulatory factor 1
chr9_-_123688352	0.725		TRAF1	TNF receptor-associated factor 1
chr16_+_77224865	0.582		MON1B	MON1 homolog B (yeast)
chr1_-_184943673	0.544	NM_052966	FAM129A	family with sequence similarity 129, member A
chr11_+_102188180	0.534	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr21_+_46293925	0.444
chr8_+_106331146	0.433	NM_012082	ZFPM2	zinc finger protein, multitype 2
chr16_+_77224827	0.424	NM_014940	MON1B	MON1 homolog B (yeast)
chr12_-_26277807	0.412	NM_030762	BHLHE41	basic helix-loop-helix family, member e41
chr16_+_77225107	0.407		MON1B	MON1 homolog B (yeast)
chr3_-_79817058	0.375	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_56632644	0.354	NM_001002836	ZNF787	zinc finger protein 787
chr5_+_56111379	0.337		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr17_-_4851688	0.334		PFN1	profilin 1
chr2_-_100721792	0.326	NM_001025108	AFF3	AF4/FMR2 family, member 3
chr4_-_38666429	0.321		FLJ13197	uncharacterized FLJ13197
chrX_+_140982451	0.316	NM_177456	MAGEC3	melanoma antigen family C, 3
chr3_+_10206562	0.316	NM_001570	IRAK2	interleukin-1 receptor-associated kinase 2
chr11_-_57194556	0.313		SLC43A3	solute carrier family 43, member 3
chr1_+_222886728	0.312		BROX	BRO1 domain and CAAX motif containing
chr1_+_180882312	0.310	NM_020950	KIAA1614	KIAA1614
chr17_-_4851797	0.310	NM_005022	PFN1	profilin 1
chr12_+_7942025	0.310		NANOG	Nanog homeobox
chr1_+_18957499	0.308	NM_001135254 NM_002584 NM_013945	PAX7	paired box 7
chr20_-_10654429	0.305	NM_000214	JAG1	jagged 1
chr19_-_11039086	0.303	NM_024029	YIPF2	Yip1 domain family, member 2
chr1_-_161102367	0.297		DEDD	death effector domain containing
chr17_-_26697310	0.295		VTN	vitronectin
chr11_-_3862137	0.294		RHOG	ras homolog gene family, member G (rho G)
chr4_-_121993568	0.289	NM_024574	NDNF	neuron-derived neurotrophic factor
chr1_-_184943532	0.284		FAM129A	family with sequence similarity 129, member A
chr11_-_71791734	0.279		NUMA1	nuclear mitotic apparatus protein 1
chr12_+_117348710	0.277	NM_012174 NM_153348	FBXW8	F-box and WD repeat domain containing 8
chr1_-_161102457	0.277	NM_001039711 NM_032998	DEDD	death effector domain containing
chr17_-_4851827	0.274		PFN1	profilin 1
chr11_+_5474637	0.273	NM_001004754	OR51I2	olfactory receptor, family 51, subfamily I, member 2
chr14_+_66974848	0.273		GPHN	gephyrin
chr4_-_74964996	0.271	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr14_+_75348592	0.266	NM_001244883 NM_001933	DLST	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr13_-_99229037	0.264		STK24	serine/threonine kinase 24
chr1_-_1590403	0.263		CDK11A CDK11B	cyclin-dependent kinase 11A cyclin-dependent kinase 11B
chr10_+_102729249	0.263		SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_-_34590137	0.260	NM_001207011	CNTFR	ciliary neurotrophic factor receptor
chr20_-_30311693	0.258		BCL2L1	BCL2-like 1
chr1_-_161102210	0.257	NM_001039712	DEDD	death effector domain containing
chr11_-_57194591	0.256	NM_199329	SLC43A3	solute carrier family 43, member 3
chr19_-_1174263	0.245	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr15_+_67358194	0.244	NM_005902	SMAD3	SMAD family member 3
chr10_+_37414784	0.244	NM_052997	ANKRD30A	ankyrin repeat domain 30A
chr1_-_16482426	0.243	NM_004431	EPHA2	EPH receptor A2
chr7_-_5553401	0.241		FBXL18	F-box and leucine-rich repeat protein 18
chr6_-_143266283	0.240	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr7_+_143078395	0.239		ZYX	zyxin
chr6_+_43738757	0.239		VEGFA	vascular endothelial growth factor A
chr21_-_38639593	0.236		DSCR3	Down syndrome critical region gene 3
chr11_-_57194512	0.236	NM_014096	SLC43A3	solute carrier family 43, member 3
chr20_-_45318135	0.231	NM_033550	TP53RK	TP53 regulating kinase
chr17_-_26697224	0.230		VTN	vitronectin
chr7_+_143078358	0.230	NM_001010972 NM_003461	ZYX	zyxin
chr11_+_35160385	0.230	NM_000610 NM_001001389 NM_001001390 NM_001001391 NM_001001392 NM_001202555 NM_001202556 NM_001202557	CD44	CD44 molecule (Indian blood group)
chr1_+_222886655	0.222		BROX	BRO1 domain and CAAX motif containing
chr12_+_6309475	0.220	NM_001769	CD9	CD9 molecule
chr18_+_55102777	0.218	NM_004852	ONECUT2	one cut homeobox 2
chr2_+_71295685	0.215		NAGK	N-acetylglucosamine kinase
chr8_-_67579362	0.214		VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1
chr17_+_21188021	0.212		MAP2K3	mitogen-activated protein kinase kinase 3
chrX_+_117480416	0.212		WDR44	WD repeat domain 44
chr14_+_103592663	0.212	NM_006291	TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr10_+_127408225	0.211		C10orf137	chromosome 10 open reading frame 137
chr22_+_37257004	0.211	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr1_-_205290756	0.210	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr17_-_26972165	0.209		KIAA0100	KIAA0100
chr8_-_67579377	0.207		VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1
chr20_+_44035203	0.206	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_-_47082529	0.206	NM_201403	MOB3C	MOB kinase activator 3C
chr19_+_11909360	0.200	NM_152356	ZNF491	zinc finger protein 491
chr9_-_133814236	0.198	NM_032843	FIBCD1	fibrinogen C domain containing 1
chr17_+_72427535	0.196	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr11_-_18813127	0.195	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr20_+_44034632	0.193	NM_001197139 NM_001048221 NM_001048222 NM_001197140 NM_018478	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr15_-_75871626	0.191		PTPN9	protein tyrosine phosphatase, non-receptor type 9
chr15_+_65134081	0.190	NM_001195059 NM_025201	PLEKHO2	pleckstrin homology domain containing, family O member 2
chr17_-_26697293	0.189		VTN	vitronectin
chr2_-_31805968	0.189	NM_000348	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
chr1_-_54871681	0.188		SSBP3	single stranded DNA binding protein 3
chr10_+_104155431	0.187	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_+_143078457	0.187		ZYX	zyxin
chr3_-_79068542	0.186	NM_001145845 NM_133631	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr22_-_32026783	0.186	NM_014338	PISD	phosphatidylserine decarboxylase
chr2_+_109745996	0.186	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr19_+_50084586	0.185	NM_000951	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr1_+_184356186	0.184		C1orf21	chromosome 1 open reading frame 21
chr7_+_143078399	0.184		ZYX	zyxin
chr21_+_43639202	0.184	NM_004915 NM_016818	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr1_-_31712733	0.183	NM_024522	NKAIN1	Na+/K+ transporting ATPase interacting 1
chrX_-_119249774	0.183	NM_139282	RHOXF1	Rhox homeobox family, member 1
chr19_-_55791727	0.183	NM_001130106 NM_012267	HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_-_3786221	0.182		MATK	megakaryocyte-associated tyrosine kinase
chr1_-_27339448	0.182		FAM46B	family with sequence similarity 46, member B
chr11_-_72433379	0.182	NM_001135190 NM_015242	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_-_47104456	0.182	NM_001205281	LOC100506012	serine/threonine-protein phosphatase 5-like
chr20_+_9494995	0.181	NM_001199897 NM_012261	LAMP5	lysosomal-associated membrane protein family, member 5
chr21_+_27011588	0.180	NM_021219	JAM2	junctional adhesion molecule 2
chr4_+_78978723	0.179	NM_001166133 NM_025074	FRAS1	Fraser syndrome 1
chr16_-_69373473	0.178	NM_032382	COG8	component of oligomeric golgi complex 8
chr10_-_99161013	0.177	NM_001145114 NM_015179	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)
chr11_+_47430045	0.177	NM_001128225 NM_152264	SLC39A13	solute carrier family 39 (zinc transporter), member 13
chr18_-_28681885	0.176	NM_004949 NM_024422	DSC2	desmocollin 2
chr12_-_57505121	0.175		STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr7_-_108096693	0.175	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chrX_-_107979606	0.174	NM_003604	IRS4	insulin receptor substrate 4
chr5_+_115298136	0.173	NM_173800	AQPEP	laeverin
chr22_-_17602142	0.173	NM_031890 NM_001163079	CECR6	cat eye syndrome chromosome region, candidate 6
chr19_-_55791446	0.172		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr15_-_75871508	0.172	NM_002833	PTPN9	protein tyrosine phosphatase, non-receptor type 9
chr11_-_65667809	0.171		FOSL1	FOS-like antigen 1
chr2_-_225907312	0.171	NM_014689	DOCK10	dedicator of cytokinesis 10
chr6_-_154831704	0.171	NM_173515	CNKSR3	CNKSR family member 3
chr7_+_143078444	0.170		ZYX	zyxin
chr19_-_55791428	0.169		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_+_1243971	0.168	NM_153339	PUSL1	pseudouridylate synthase-like 1
chr2_-_136743076	0.166		DARS	aspartyl-tRNA synthetase
chr11_-_65667860	0.165	NM_005438	FOSL1	FOS-like antigen 1
chr19_+_13105970	0.165	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr21_+_43639930	0.163	NM_207174	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr20_-_10654139	0.163		JAG1	jagged 1
chr9_-_133813988	0.162		FIBCD1	fibrinogen C domain containing 1
chr19_+_39390258	0.162	NM_001243116	NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr15_+_74908195	0.162		CLK3	CDC-like kinase 3
chr2_-_136743189	0.161	NM_001349	DARS	aspartyl-tRNA synthetase
chr19_-_1174201	0.161
chr12_-_6740814	0.160	NM_001142961	LPAR5	lysophosphatidic acid receptor 5
chr6_-_31324975	0.160	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr7_-_37488408	0.160		ELMO1	engulfment and cell motility 1
chr9_-_33473846	0.160		NOL6	nucleolar protein family 6 (RNA-associated)
chr5_-_150460599	0.160	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr10_+_23983674	0.158	NM_001098500	KIAA1217	KIAA1217
chr7_+_108210308	0.158		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_168043792	0.157	NM_001199144 NM_001199145	XIRP2	xin actin-binding repeat containing 2
chr19_-_55791490	0.157		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_-_228604582	0.157	NM_001024940 NM_001134855 NM_016102	TRIM17	tripartite motif containing 17
chr4_-_185747051	0.157		ACSL1	acyl-CoA synthetase long-chain family member 1
chr17_+_46985720	0.155	NM_023079	UBE2Z	ubiquitin-conjugating enzyme E2Z
chr18_-_28681429	0.154		DSC2	desmocollin 2
chr12_-_57505176	0.153	NM_001178078 NM_001178080 NM_001178081 NM_003153	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr11_+_65479685	0.153		KAT5	K(lysine) acetyltransferase 5
chr1_-_228604305	0.152		TRIM17	tripartite motif containing 17
chr1_+_229761988	0.152		URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr19_+_10982369	0.152		CARM1	coactivator-associated arginine methyltransferase 1
chr3_-_158450271	0.152	NM_002888 NM_206963	RARRES1	retinoic acid receptor responder (tazarotene induced) 1
chr6_+_99282597	0.151		POU3F2	POU class 3 homeobox 2
chr5_-_150460550	0.150		TNIP1	TNFAIP3 interacting protein 1
chr17_+_46985829	0.150		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr15_+_69706619	0.150	NM_004856 NM_138555	KIF23	kinesin family member 23
chr15_+_74287148	0.149		PML	promyelocytic leukemia
chr1_-_120612301	0.149	NM_001200001 NM_024408	NOTCH2	notch 2
chr2_-_136743037	0.149		DARS	aspartyl-tRNA synthetase
chr22_+_32340592	0.148		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr1_-_33336289	0.148	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr2_+_150187028	0.146	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr1_+_206643786	0.146		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr18_+_21719447	0.146	NM_138644	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr22_+_31518923	0.145	NM_001002837	INPP5J	inositol polyphosphate-5-phosphatase J
chr1_-_38273823	0.144		YRDC	yrdC domain containing (E. coli)
chr8_+_31497267	0.143	NM_013962	NRG1	neuregulin 1
chr3_-_187454247	0.142	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr21_+_27011766	0.142		JAM2	junctional adhesion molecule 2
chr17_+_7255207	0.142	NM_001002914	KCTD11	potassium channel tetramerisation domain containing 11
chr11_+_7273141	0.142	NM_175733	SYT9	synaptotagmin IX
chr3_-_158450230	0.141		RARRES1	retinoic acid receptor responder (tazarotene induced) 1
chr11_-_65667858	0.140		FOSL1	FOS-like antigen 1
chr2_-_131850988	0.140	NM_001009993	FAM168B	family with sequence similarity 168, member B
chr1_-_12677347	0.139	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr1_-_894651	0.139	NM_015658	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)
chr7_-_142583260	0.139	NM_018646	TRPV6	transient receptor potential cation channel, subfamily V, member 6
chr10_+_99400469	0.139		PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr14_+_24630421	0.138	NM_006084	IRF9	interferon regulatory factor 9
chr16_-_69373406	0.138		COG8	component of oligomeric golgi complex 8
chr7_-_2354010	0.138		SNX8	sorting nexin 8
chr7_+_108210188	0.137	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr18_+_21718930	0.137	NM_012189 NM_138643 NM_153768 NM_153769 NM_153770	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr2_-_239197091	0.137	NM_022817	PER2	period homolog 2 (Drosophila)
chr6_+_44095357	0.137	NM_018426	TMEM63B	transmembrane protein 63B
chr3_+_5021096	0.137	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr19_+_38794800	0.137	NM_033520	C19orf33	chromosome 19 open reading frame 33
chr1_+_154975041	0.137	NM_001252405 NM_015872	ZBTB7B	zinc finger and BTB domain containing 7B
chr1_+_170501240	0.136	NM_001146039 NM_152281	GORAB	golgin, RAB6-interacting
chr6_+_29974352	0.136		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr22_+_32750871	0.136	NM_006604	RFPL3	ret finger protein-like 3
chr11_+_35160666	0.136		CD44	CD44 molecule (Indian blood group)
chr1_+_156084579	0.136		LMNA	lamin A/C
chr16_-_86542463	0.134		LOC400550	uncharacterized LOC400550
chr15_+_74287132	0.134		PML	promyelocytic leukemia
chr19_-_1174257	0.134		SBNO2	strawberry notch homolog 2 (Drosophila)
chr21_-_35899046	0.133	NM_203418	RCAN1	regulator of calcineurin 1
chr2_+_54683276	0.133	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chrX_+_70315637	0.132	NM_001170931 NM_005938	FOXO4	forkhead box O4
chr17_+_41561232	0.132	NM_004941	DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr10_+_99400441	0.132	NM_018425	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.11	2.68e-12	GO:0009987	cellular process
1.14	5.63e-08	GO:0065007	biological regulation
1.14	5.37e-07	GO:0050794	regulation of cellular process
1.29	6.86e-07	GO:0048522	positive regulation of cellular process
1.27	1.12e-06	GO:0048518	positive regulation of biological process
1.13	6.02e-06	GO:0050789	regulation of biological process
1.26	5.34e-05	GO:0048519	negative regulation of biological process
1.54	1.26e-04	GO:0042060	wound healing
1.20	1.51e-04	GO:0071840	cellular component organization or biogenesis
1.54	2.20e-04	GO:0050878	regulation of body fluid levels
1.20	2.52e-04	GO:0016043	cellular component organization
1.26	2.67e-04	GO:0048523	negative regulation of cellular process
1.22	4.60e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.16	5.65e-04	GO:0044260	cellular macromolecule metabolic process
1.23	6.19e-04	GO:0071842	cellular component organization at cellular level
1.31	8.12e-04	GO:0007399	nervous system development
1.15	1.04e-03	GO:0043170	macromolecule metabolic process
1.20	1.33e-03	GO:0048856	anatomical structure development
1.17	4.30e-03	GO:0032502	developmental process
1.27	4.77e-03	GO:0023051	regulation of signaling
1.50	8.59e-03	GO:0007599	hemostasis
1.35	8.95e-03	GO:0042127	regulation of cell proliferation
1.11	1.03e-02	GO:0044237	cellular metabolic process
1.50	1.05e-02	GO:0007596	blood coagulation
1.50	1.05e-02	GO:0050817	coagulation
1.28	1.16e-02	GO:0009966	regulation of signal transduction
1.36	1.19e-02	GO:0009611	response to wounding
1.16	1.61e-02	GO:0031323	regulation of cellular metabolic process
1.16	2.16e-02	GO:0007275	multicellular organismal development
1.70	2.57e-02	GO:0030168	platelet activation
1.33	2.71e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.43	2.74e-02	GO:0010629	negative regulation of gene expression
1.22	3.08e-02	GO:0030154	cell differentiation
1.18	4.08e-02	GO:0048731	system development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	1.64e-09	GO:0005737	cytoplasm
1.08	1.58e-08	GO:0005622	intracellular
1.08	2.42e-08	GO:0044424	intracellular part
1.26	3.21e-05	GO:0005829	cytosol
1.14	6.05e-05	GO:0005634	nucleus
1.12	3.03e-04	GO:0044444	cytoplasmic part
1.08	3.21e-04	GO:0043226	organelle
1.08	4.21e-04	GO:0043229	intracellular organelle
1.19	6.09e-04	GO:0043234	protein complex
1.03	1.31e-03	GO:0044464	cell part
1.03	1.38e-03	GO:0005623	cell
1.08	2.19e-03	GO:0043231	intracellular membrane-bounded organelle
1.08	2.43e-03	GO:0043227	membrane-bounded organelle
1.22	1.05e-02	GO:0031981	nuclear lumen
1.11	1.27e-02	GO:0044422	organelle part
1.11	1.48e-02	GO:0044446	intracellular organelle part
1.30	1.73e-02	GO:0005794	Golgi apparatus
1.19	2.14e-02	GO:0044459	plasma membrane part
1.19	2.20e-02	GO:0043233	organelle lumen
1.19	2.35e-02	GO:0070013	intracellular organelle lumen
1.18	2.45e-02	GO:0031974	membrane-enclosed lumen
1.35	2.92e-02	GO:0015630	microtubule cytoskeleton
1.18	4.33e-02	GO:0044428	nuclear part
1.36	4.96e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	4.08e-22	GO:0005515	protein binding
1.07	6.84e-07	GO:0005488	binding