Motif ID: ETS1,2.p2

Z-value: 0.768


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ETS1chr11_-_1283920610.386.4e-02Click!
ETS2chr21_+_401778470.252.3e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_169703178 1.545 NM_000450
SELE
selectin E
chr11_-_46722139 1.452 ARHGAP1
Rho GTPase activating protein 1
chr11_-_46722160 1.311 ARHGAP1
Rho GTPase activating protein 1
chr17_+_32582295 0.917 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr1_-_160313056 0.895 COPA
coatomer protein complex, subunit alpha
chr21_+_26934440 0.797 MIR155HG
MIR155 host gene (non-protein coding)
chr19_+_39899749 0.781


chr16_+_29674564 0.771 SPN
sialophorin
chr1_-_160312959 0.736


chr5_-_131826426 0.685 NM_002198
IRF1
interferon regulatory factor 1
chr5_+_118604417 0.674 NM_001077654
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_150148078 0.668 GIMAP8
GTPase, IMAP family member 8
chr10_+_49892860 0.662 WDFY4
WDFY family member 4
chr4_-_74964836 0.654 CXCL2
chemokine (C-X-C motif) ligand 2
chr5_+_56111379 0.646 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr19_+_42387249 0.638 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr6_-_10412606 0.621 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_-_123688352 0.601 TRAF1
TNF receptor-associated factor 1
chr19_+_42387307 0.579 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr14_+_103592663 0.576 NM_006291
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr5_-_141704575 0.566 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr12_-_49259549 0.566 NM_014470
RND1
Rho family GTPase 1
chr11_+_2421983 0.556 TSSC4
tumor suppressing subtransferable candidate 4
chr6_-_11382501 0.554 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr17_+_9729380 0.547 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr15_+_71184781 0.538 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr6_+_14117486 0.536 NM_001251901
CD83
CD83 molecule
chr5_+_125758818 0.533 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr2_+_237478379 0.530 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr7_+_150434679 0.523 GIMAP5
GTPase, IMAP family member 5
chr1_-_154946859 0.521 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr4_-_16900028 0.516 LDB2
LIM domain binding 2
chr9_-_123676849 0.514 NM_001190947
TRAF1
TNF receptor-associated factor 1
chr4_-_16900256 0.512 LDB2
LIM domain binding 2
chr5_-_32312943 0.512 MTMR12
myotubularin related protein 12
chr11_-_46722115 0.508 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr1_+_10003526 0.505 NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr19_-_56632600 0.505 ZNF787
zinc finger protein 787
chr19_+_16296211 0.504 NM_014077
FAM32A
family with sequence similarity 32, member A
chr4_-_16900348 0.503 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr15_-_64338519 0.502 NM_014326
DAPK2
death-associated protein kinase 2
chr21_+_33784751 0.493 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr1_-_41328019 0.486 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr8_+_86157693 0.470 NM_198584
CA13
carbonic anhydrase XIII
chr3_-_11685395 0.459 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr4_+_103422479 0.459 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr8_+_86089641 0.457


chr19_-_56632644 0.453 NM_001002836
ZNF787
zinc finger protein 787
chr5_-_892613 0.445 NM_001009877
BRD9
bromodomain containing 9
chr4_+_103422553 0.444 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr15_+_81293286 0.441 NM_022566
MESDC1
mesoderm development candidate 1
chr5_+_125759076 0.441 GRAMD3
GRAM domain containing 3
chr1_-_154946830 0.440 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr8_+_86089618 0.437 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr7_+_150147882 0.427 GIMAP8
GTPase, IMAP family member 8
chr6_+_126240369 0.425 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr1_+_155100304 0.423 NM_004428
NM_182685
EFNA1

ephrin-A1

chr5_-_892918 0.419 NM_023924
BRD9
bromodomain containing 9
chr1_+_155533013 0.418 LOC645676
uncharacterized LOC645676
chr21_+_43636186 0.413 NM_207629
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr21_+_43619798 0.413 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr1_-_160313029 0.410 COPA
coatomer protein complex, subunit alpha
chr9_-_130616592 0.410 ENG
endoglin
chr9_-_130667571 0.402 LOC100131355
ST6GALNAC6
uncharacterized LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_-_8739398 0.401 ST5
suppression of tumorigenicity 5
chr7_+_76178604 0.400 LOC100133091
uncharacterized LOC100133091
chr9_+_130854127 0.397 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_11267666 0.394 NM_001098211
HRH1
histamine receptor H1
chr12_-_6798419 0.394 ZNF384
zinc finger protein 384
chr9_+_116356407 0.393 RGS3
regulator of G-protein signaling 3
chr5_+_149380168 0.392 NM_014983
HMGXB3
HMG box domain containing 3
chr5_-_892914 0.392 BRD9
bromodomain containing 9
chr12_+_100660846 0.389 SCYL2
SCY1-like 2 (S. cerevisiae)
chr12_-_6233684 0.389 NM_000552
VWF
von Willebrand factor
chr18_+_23713815 0.386 NM_001025096
NM_001025097
NM_144662
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr1_-_161601752 0.386 NM_000570
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr14_+_73603140 0.385 NM_000021
NM_007318
PSEN1

presenilin 1

chr19_-_1174263 0.384 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr16_+_31085722 0.384 NM_014699
ZNF646
zinc finger protein 646
chrX_-_45060081 0.383 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr7_+_150065330 0.374 REPIN1
replication initiator 1
chr16_-_50715116 0.368 SNX20
sorting nexin 20
chr7_+_50348255 0.366 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_182970853 0.365 NM_032047
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_+_6186758 0.364 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_+_108210188 0.363 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr10_+_6186878 0.362 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_222886728 0.360 BROX
BRO1 domain and CAAX motif containing
chr19_+_11546467 0.357 PRKCSH
protein kinase C substrate 80K-H
chr21_-_33984865 0.355 NM_021254
C21orf59
chromosome 21 open reading frame 59
chr19_-_1174257 0.355 SBNO2
strawberry notch homolog 2 (Drosophila)
chr17_+_40610905 0.354 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr13_+_111806070 0.353 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr15_+_67358161 0.352 SMAD3
SMAD family member 3
chr15_+_67430358 0.351 NM_001145103
SMAD3
SMAD family member 3
chr13_+_111806038 0.351 NM_003899
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr15_+_91473409 0.350 NM_001039675
UNC45A
unc-45 homolog A (C. elegans)
chr12_+_100661158 0.350 SCYL2
SCY1-like 2 (S. cerevisiae)
chr17_+_40610940 0.348 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr7_+_150434435 0.346 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr5_+_140071014 0.343 NM_012208
HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr1_-_41328002 0.342 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr10_+_112257624 0.340 NM_004419
DUSP5
dual specificity phosphatase 5
chr17_+_40610897 0.338 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_-_123214882 0.336 NM_032554
HCAR1
hydroxycarboxylic acid receptor 1
chrX_+_67913490 0.335 STARD8
StAR-related lipid transfer (START) domain containing 8
chr19_+_47759730 0.335 NM_015603
CCDC9
coiled-coil domain containing 9
chrX_+_67913479 0.334 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr16_+_31085751 0.334 ZNF646
zinc finger protein 646
chr4_+_8200918 0.333 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr14_-_23284617 0.332 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_+_116356199 0.332 NM_144489
RGS3
regulator of G-protein signaling 3
chr20_-_62339309 0.332 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr3_-_149051258 0.331 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr14_-_38725539 0.331 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr13_+_52586516 0.329 NM_001004127
ALG11
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
chr19_+_11546447 0.329 PRKCSH
protein kinase C substrate 80K-H
chr11_+_114166534 0.324 NM_006169
NNMT
nicotinamide N-methyltransferase
chr10_-_88717319 0.322 NM_024756
MMRN2
multimerin 2
chr9_-_114937464 0.321 NM_022486
SUSD1
sushi domain containing 1
chr5_+_118691692 0.320 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr19_-_1174201 0.320


chr1_-_155948317 0.320 NM_001162383
NM_001162384
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

chr2_-_208489695 0.319 NM_145280
METTL21A
methyltransferase like 21A
chr1_-_150552077 0.319 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr19_+_47759802 0.318 CCDC9
coiled-coil domain containing 9
chr1_-_1310817 0.317 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr17_+_40610875 0.317 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr22_+_33196801 0.316 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_220110116 0.315 NM_024506
GLB1L
galactosidase, beta 1-like
chr3_+_46448678 0.313 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr7_+_108210291 0.311 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr19_+_12902295 0.310 NM_002229
JUNB
jun B proto-oncogene
chr1_-_27240430 0.309 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr20_-_48532036 0.306 SPATA2
spermatogenesis associated 2
chr8_+_90770201 0.303 RIPK2
receptor-interacting serine-threonine kinase 2
chr3_+_182971213 0.303 B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_+_150147936 0.303 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr1_+_38273817 0.302 C1orf122
chromosome 1 open reading frame 122
chr1_+_61547388 0.300 NM_001145512
NFIA
nuclear factor I/A
chr2_-_64881040 0.300 NM_014755
SERTAD2
SERTA domain containing 2
chr20_+_62612464 0.297 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr12_+_123465359 0.297 ARL6IP4
ADP-ribosylation-like factor 6 interacting protein 4
chr5_+_149380287 0.297 HMGXB3
HMG box domain containing 3
chr5_+_149380301 0.296 HMGXB3
HMG box domain containing 3
chr15_-_40600025 0.295 PLCB2
phospholipase C, beta 2
chr2_+_173686314 0.294 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_139163222 0.294 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr20_+_62184372 0.293 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr4_-_101439071 0.292 NM_001159694
NM_016242
EMCN

endomucin

chr14_-_100842637 0.292 WARS
tryptophanyl-tRNA synthetase
chr5_-_141704468 0.290 SPRY4
sprouty homolog 4 (Drosophila)
chr1_-_161039586 0.290 ARHGAP30
Rho GTPase activating protein 30
chr22_+_45704821 0.286 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr11_+_66824308 0.286 RHOD
ras homolog gene family, member D
chr3_-_187454247 0.285 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr5_+_149380310 0.285 HMGXB3
HMG box domain containing 3
chr11_+_44785975 0.284 NM_130783
TSPAN18
tetraspanin 18
chr22_-_43089856 0.284 A4GALT
alpha 1,4-galactosyltransferase
chr16_+_284833 0.281 ITFG3
integrin alpha FG-GAP repeat containing 3
chr11_-_119211526 0.281 C1QTNF5
MFRP
C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein
chr1_+_212738675 0.281 NM_001030287
ATF3
activating transcription factor 3
chr7_-_5569200 0.280 ACTB
actin, beta
chr5_-_1112106 0.280 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr1_+_32538497 0.280 NM_018056
TMEM39B
transmembrane protein 39B
chr1_-_154946801 0.277 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr6_-_33290678 0.277 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr11_-_60673854 0.277 PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr1_-_157108132 0.275 ETV3
ets variant 3
chr7_+_100770378 0.275 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr5_+_140071141 0.275 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr20_-_42839295 0.275 C20orf111
chromosome 20 open reading frame 111
chr5_+_10353980 0.272


chr8_+_22437983 0.271 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr16_+_3493605 0.271 NM_001083601
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr9_-_130616957 0.270 ENG
endoglin
chr1_+_46049659 0.270 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr22_+_50354139 0.270 NM_001001852
PIM3
pim-3 oncogene
chr1_+_38273468 0.269 NM_001142726
NM_198446
C1orf122

chromosome 1 open reading frame 122

chr1_+_37940129 0.267 ZC3H12A
zinc finger CCCH-type containing 12A
chr21_-_43373938 0.267 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr20_+_62612493 0.267 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr3_-_50378238 0.263 NM_001206957
NM_007182
NM_170714
RASSF1


Ras association (RalGDS/AF-6) domain family member 1


chr11_-_417324 0.262 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr8_-_101322180 0.262 RNF19A
ring finger protein 19A
chr3_+_50284325 0.261 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr6_+_31515352 0.260 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr5_-_149380121 0.260 NM_001243253
LOC728287
TIGD6
uncharacterized LOC728287
tigger transposable element derived 6
chr8_+_100025534 0.260 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr9_-_134585107 0.259 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr5_+_140739589 0.258 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr19_+_11546485 0.258 PRKCSH
protein kinase C substrate 80K-H
chr14_+_76618289 0.258 C14orf118
chromosome 14 open reading frame 118
chr7_-_150329285 0.257 GIMAP6
GTPase, IMAP family member 6
chr1_-_205290756 0.257 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr8_+_145133617 0.257


chr12_+_123465041 0.257 ARL6IP4
ADP-ribosylation-like factor 6 interacting protein 4
chr9_-_130616760 0.256 ENG
endoglin
chr6_+_10555948 0.255 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr4_-_74904329 0.255 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 7.09e-12 GO:0009987 cellular process
1.22 1.55e-08 GO:0044260 cellular macromolecule metabolic process
1.20 2.30e-08 GO:0043170 macromolecule metabolic process
1.32 8.28e-06 GO:0048583 regulation of response to stimulus
1.22 1.79e-05 GO:0007165 signal transduction
1.63 3.63e-05 GO:0001775 cell activation
1.36 8.24e-05 GO:0035556 intracellular signal transduction
1.25 1.04e-04 GO:0044267 cellular protein metabolic process
1.11 1.10e-04 GO:0065007 biological regulation
1.36 1.93e-04 GO:0002376 immune system process
1.29 1.98e-04 GO:0006464 protein modification process
1.18 2.20e-04 GO:0051716 cellular response to stimulus
1.20 2.34e-04 GO:0016043 cellular component organization
1.28 2.42e-04 GO:0043412 macromolecule modification
1.12 4.22e-04 GO:0008152 metabolic process
1.19 4.89e-04 GO:0071840 cellular component organization or biogenesis
1.93 6.17e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.93 6.17e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
1.18 7.09e-04 GO:0023052 signaling
1.11 8.44e-04 GO:0050789 regulation of biological process
1.11 1.28e-03 GO:0050794 regulation of cellular process
1.88 1.70e-03 GO:0000375 RNA splicing, via transesterification reactions
1.12 2.03e-03 GO:0044237 cellular metabolic process
1.31 2.73e-03 GO:0009966 regulation of signal transduction
1.12 4.08e-03 GO:0044238 primary metabolic process
1.20 4.13e-03 GO:0019538 protein metabolic process
1.36 4.44e-03 GO:0032268 regulation of cellular protein metabolic process
1.35 4.70e-03 GO:0051246 regulation of protein metabolic process
1.44 5.13e-03 GO:0043085 positive regulation of catalytic activity
1.48 5.60e-03 GO:0042060 wound healing
1.33 6.39e-03 GO:0050790 regulation of catalytic activity
1.39 7.74e-03 GO:0044093 positive regulation of molecular function
1.20 8.90e-03 GO:0048518 positive regulation of biological process
1.41 9.44e-03 GO:0006955 immune response
1.51 1.03e-02 GO:0007599 hemostasis
1.41 1.06e-02 GO:0006468 protein phosphorylation
1.50 1.07e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.50 1.28e-02 GO:0007596 blood coagulation
1.50 1.28e-02 GO:0050817 coagulation
1.58 1.34e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.36 1.40e-02 GO:0009611 response to wounding
1.41 1.61e-02 GO:0002682 regulation of immune system process
1.34 1.68e-02 GO:0006793 phosphorus metabolic process
1.34 1.68e-02 GO:0006796 phosphate metabolic process
1.52 1.79e-02 GO:0002684 positive regulation of immune system process
1.37 1.95e-02 GO:0016310 phosphorylation
1.73 1.98e-02 GO:0030168 platelet activation
1.27 3.19e-02 GO:0065009 regulation of molecular function
1.49 3.25e-02 GO:0045859 regulation of protein kinase activity
1.20 3.39e-02 GO:0006950 response to stress
2.01 3.55e-02 GO:0007265 Ras protein signal transduction
1.20 4.60e-02 GO:0048522 positive regulation of cellular process
1.44 4.65e-02 GO:0050878 regulation of body fluid levels
1.41 4.75e-02 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 3.66e-09 GO:0005737 cytoplasm
1.08 5.82e-08 GO:0005622 intracellular
1.08 7.27e-08 GO:0044424 intracellular part
1.13 3.53e-05 GO:0044444 cytoplasmic part
1.25 1.36e-04 GO:0005829 cytosol
1.12 3.00e-03 GO:0044422 organelle part
1.12 5.68e-03 GO:0044446 intracellular organelle part
1.08 6.36e-03 GO:0043227 membrane-bounded organelle
1.07 9.77e-03 GO:0043226 organelle
1.08 1.01e-02 GO:0043231 intracellular membrane-bounded organelle
1.07 1.25e-02 GO:0043229 intracellular organelle
1.19 1.63e-02 GO:0031974 membrane-enclosed lumen
2.77 1.71e-02 GO:0032587 ruffle membrane
1.72 2.65e-02 GO:0031252 cell leading edge
1.18 3.25e-02 GO:0043233 organelle lumen
1.19 3.56e-02 GO:0044428 nuclear part
1.21 3.91e-02 GO:0031981 nuclear lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 1.04e-18 GO:0005515 protein binding
1.06 6.08e-05 GO:0005488 binding
1.44 1.29e-03 GO:0046983 protein dimerization activity
1.51 4.65e-03 GO:0019904 protein domain specific binding
1.37 9.89e-03 GO:0042802 identical protein binding
1.52 1.50e-02 GO:0000988 protein binding transcription factor activity
1.52 1.50e-02 GO:0000989 transcription factor binding transcription factor activity
1.51 2.34e-02 GO:0003712 transcription cofactor activity