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• Activity deltas table
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Motif ID: FOXA2.p3

Z-value: 0.956

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_41700736	3.449		LIMCH1	LIM and calponin homology domains 1
chr1_+_84609941	2.629	NM_182948	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr12_-_15038724	2.291	NM_000900 NM_001190839	MGP	matrix Gla protein
chr2_-_165424993	2.217		GRB14	growth factor receptor-bound protein 14
chr8_-_93029864	2.136	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_80993009	1.885	NM_001025252	TPD52	tumor protein D52
chr6_+_132891460	1.865	NM_175067	TAAR6	trace amine associated receptor 6
chrX_-_63005212	1.836	NM_001173479	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_61547388	1.737	NM_001145512	NFIA	nuclear factor I/A
chr12_-_9268513	1.711		A2M	alpha-2-macroglobulin
chr12_-_9268440	1.693		A2M	alpha-2-macroglobulin
chr14_+_56585147	1.583		PELI2	pellino homolog 2 (Drosophila)
chr16_-_86542463	1.554		LOC400550	uncharacterized LOC400550
chr4_-_186732208	1.518	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr11_-_33913835	1.459	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_+_77469446	1.452	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr10_-_125853102	1.429		CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr6_-_112575766	1.399	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr12_-_9268475	1.390		A2M	alpha-2-macroglobulin
chr12_-_9268522	1.332	NM_000014	A2M	alpha-2-macroglobulin
chr8_-_28243941	1.319	NM_018660	ZNF395	zinc finger protein 395
chr2_-_191872322	1.312		STAT1	signal transducer and activator of transcription 1, 91kDa
chr14_+_56584854	1.296	NM_021255	PELI2	pellino homolog 2 (Drosophila)
chr13_-_48987017	1.292		LPAR6	lysophosphatidic acid receptor 6
chr9_-_75568232	1.282	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr5_+_68788118	1.276	NM_002538	OCLN	occludin
chrX_-_10851808	1.268	NM_033290	MID1	midline 1 (Opitz/BBB syndrome)
chr18_-_53071225	1.258	NM_001243232	TCF4	transcription factor 4
chr9_-_8733893	1.198	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr13_-_48987247	1.165		LPAR6	lysophosphatidic acid receptor 6
chr10_+_82173574	1.162	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr19_+_35417806	1.162	NM_001099437 NM_001099438 NM_194325	ZNF30	zinc finger protein 30
chr6_-_112575880	1.147		LAMA4	laminin, alpha 4
chr12_-_76425375	1.127	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr11_-_17191287	1.126	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr2_-_188312872	1.111	NM_005795	CALCRL	calcitonin receptor-like
chr12_+_13349720	1.100		EMP1	epithelial membrane protein 1
chr2_+_132480063	1.084	NM_013310	C2orf27A	chromosome 2 open reading frame 27A
chr2_+_173686314	1.035	NM_001100397	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr17_+_48172100	1.014	NM_001199898	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr12_+_13349601	1.005	NM_001423	EMP1	epithelial membrane protein 1
chr20_+_33759773	1.004	NM_006404	PROCR	protein C receptor, endothelial
chr9_+_79115548	1.003	NM_001097636	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chr17_+_9745847	0.996		GLP2R	glucagon-like peptide 2 receptor
chr8_-_93115453	0.989	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_23288912	0.985	NM_001126106	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_152149042	0.983	NM_001243349	SH3D19	SH3 domain containing 19
chr3_+_132316080	0.970	NM_016557	CCRL1	chemokine (C-C motif) receptor-like 1
chr18_+_72922725	0.941	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr18_-_22930826	0.938
chr13_-_48987652	0.931	NM_001162498	LPAR6	lysophosphatidic acid receptor 6
chr12_+_93963597	0.905	NM_003877	SOCS2	suppressor of cytokine signaling 2
chr6_-_134373618	0.887	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr9_+_129724503	0.876	NM_001190728	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr6_-_76203256	0.866	NM_015687	FILIP1	filamin A interacting protein 1
chr5_+_42565963	0.861	NM_001242460 NM_001242461 NM_001242462	GHR	growth hormone receptor
chr17_-_29641068	0.853		EVI2B	ecotropic viral integration site 2B
chr17_-_16097882	0.853	NM_001190438 NM_001190440	NCOR1	nuclear receptor corepressor 1
chr6_+_74405856	0.847		CD109	CD109 molecule
chr1_+_117544371	0.841	NM_004258	CD101	CD101 molecule
chr8_+_70405080	0.816		SULF1	sulfatase 1
chr4_+_70861647	0.808	NM_001009181 NM_003154	STATH	statherin
chr10_+_99400469	0.803		PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr21_-_40033617	0.803	NM_001243432 NM_001136154 NM_004449	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr15_+_80390757	0.788	NM_001242919	ZFAND6	zinc finger, AN1-type domain 6
chr6_-_112575708	0.786		LAMA4	laminin, alpha 4
chr6_+_74405764	0.781		CD109	CD109 molecule
chr7_+_116364175	0.781		MET	met proto-oncogene (hepatocyte growth factor receptor)
chr12_+_57943806	0.769		KIF5A	kinesin family member 5A
chr4_-_138453628	0.747	NM_019035	PCDH18	protocadherin 18
chr13_-_78493902	0.745	NM_001201397	EDNRB	endothelin receptor type B
chr5_-_88119604	0.745	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr11_-_61124223	0.744	NM_001161452	CYBASC3	cytochrome b, ascorbate dependent 3
chr2_-_191878883	0.717		STAT1	signal transducer and activator of transcription 1, 91kDa
chr1_+_26504024	0.708		CNKSR1	connector enhancer of kinase suppressor of Ras 1
chr3_+_193853930	0.699	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr7_+_89843133	0.692	NM_001040666	STEAP2	STEAP family member 2, metalloreductase
chr21_-_39956823	0.692	NM_001243429	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_106809405	0.688	NM_001244262 NM_012257	HBP1	HMG-box transcription factor 1
chr3_+_143692166	0.680	NM_001134470	C3orf58	chromosome 3 open reading frame 58
chr8_+_70405027	0.675	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr2_-_170430312	0.670	NM_024622	FASTKD1	FAST kinase domains 1
chr7_+_80267922	0.666		CD36	CD36 molecule (thrombospondin receptor)
chr9_-_75567915	0.666		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr2_-_191878908	0.658		STAT1	signal transducer and activator of transcription 1, 91kDa
chr13_+_53035227	0.657		CKAP2	cytoskeleton associated protein 2
chr7_+_1577118	0.653		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr15_+_96869156	0.648	NM_001145155	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr2_+_109223600	0.645	NM_001193482	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_-_182354649	0.643		GLUL	glutamate-ammonia ligase
chr17_-_39183453	0.636	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr22_+_35462125	0.630	NM_001008494	ISX	intestine-specific homeobox
chrX_+_102883891	0.629	NM_001006639 NM_004780	TCEAL1	transcription elongation factor A (SII)-like 1
chr19_+_40502942	0.628	NM_178544	ZNF546	zinc finger protein 546
chr9_-_34710062	0.626	NM_002989	CCL21	chemokine (C-C motif) ligand 21
chr9_+_71944240	0.625	NM_004816	FAM189A2	family with sequence similarity 189, member A2
chr7_+_31003635	0.623	NM_000823	GHRHR	growth hormone releasing hormone receptor
chr10_+_63808968	0.619	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr4_+_140586921	0.610	NM_001204366 NM_001204367 NM_001204368 NM_002413	MGST2	microsomal glutathione S-transferase 2
chr1_+_84768333	0.598	NM_001134664	SAMD13	sterile alpha motif domain containing 13
chr12_+_7341758	0.597	NM_001131026	PEX5	peroxisomal biogenesis factor 5
chr2_-_177502658	0.592		LOC375295	uncharacterized LOC375295
chr11_-_27681195	0.589	NM_001143816 NM_170735	BDNF	brain-derived neurotrophic factor
chr20_+_31755882	0.589	NM_080574	BPIFA2	BPI fold containing family A, member 2
chr5_+_42565562	0.588	NM_001242406	GHR	growth hormone receptor
chr6_+_74405505	0.587	NM_001159587 NM_001159588 NM_133493	CD109	CD109 molecule
chr1_+_87797371	0.583		LMO4	LIM domain only 4
chr11_+_844111	0.582		TSPAN4	tetraspanin 4
chr9_+_124048869	0.581		GSN	gelsolin
chr2_+_88047603	0.579	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr13_+_111855406	0.574		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr17_-_26697310	0.572		VTN	vitronectin
chr2_-_191878882	0.568		STAT1	signal transducer and activator of transcription 1, 91kDa
chr1_+_244214576	0.567		ZNF238	zinc finger protein 238
chr12_+_48516428	0.559	NM_001166687 NM_001166688	PFKM	phosphofructokinase, muscle
chr2_-_87248942	0.559	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr8_-_17579729	0.559	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr7_+_150382783	0.557	NM_015660	GIMAP2	GTPase, IMAP family member 2
chr2_+_65283485	0.556	NM_015147	CEP68	centrosomal protein 68kDa
chr3_-_168864066	0.553	NM_001105077 NM_001163999 NM_005241	MECOM	MDS1 and EVI1 complex locus
chr11_-_64377332	0.551
chr7_+_134832765	0.547	NM_018295	TMEM140	transmembrane protein 140
chr1_+_52082545	0.541	NM_024586 NM_148906 NM_148908 NM_148909	OSBPL9	oxysterol binding protein-like 9
chr2_-_27579277	0.539		GTF3C2	general transcription factor IIIC, polypeptide 2, beta 110kDa
chr5_+_68800003	0.539	NM_001205255	OCLN	occludin
chr2_-_188419049	0.535		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_+_90816002	0.535	NM_007351	MMRN1	multimerin 1
chr1_+_6615337	0.531	NM_138697 NM_177540	TAS1R1	taste receptor, type 1, member 1
chr5_+_140602914	0.530	NM_018934	PCDHB14	protocadherin beta 14
chr17_-_26697293	0.528		VTN	vitronectin
chr1_-_238054221	0.515	NM_021186	ZP4	zona pellucida glycoprotein 4
chr10_-_48416692	0.512	NM_016204	GDF2	growth differentiation factor 2
chr6_+_74405909	0.510		CD109	CD109 molecule
chr21_-_31869427	0.507	NM_181610	KRTAP19-4	keratin associated protein 19-4
chr1_-_182357757	0.507		GLUL	glutamate-ammonia ligase
chr12_+_10365415	0.502	NM_031412	GABARAPL1	GABA(A) receptor-associated protein like 1
chr8_+_143761873	0.501	NM_005672	PSCA	prostate stem cell antigen
chr12_+_101988746	0.500	NM_002465 NM_206819 NM_206820 NM_206821	MYBPC1	myosin binding protein C, slow type
chr1_-_151345156	0.500	NM_003944	SELENBP1	selenium binding protein 1
chr20_-_45976626	0.494		ZMYND8	zinc finger, MYND-type containing 8
chr12_+_96588254	0.494		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr10_-_49482912	0.493	NM_001018071	FRMPD2	FERM and PDZ domain containing 2
chr12_-_55028624	0.489	NM_033277	LACRT	lacritin
chr19_-_52150007	0.488	NM_001098612	SIGLEC14	sialic acid binding Ig-like lectin 14
chr3_+_193853937	0.486		HES1	hairy and enhancer of split 1, (Drosophila)
chr5_-_39424930	0.486		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_163038934	0.486	NM_001113381	RGS4	regulator of G-protein signaling 4
chr20_-_23066828	0.485	NM_012072	CD93	CD93 molecule
chr2_+_47630291	0.485		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr2_-_111230651	0.484	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr4_+_134073180	0.484		PCDH10	protocadherin 10
chr5_+_147774274	0.483		FBXO38	F-box protein 38
chr1_-_109935869	0.482	NM_001205228	SORT1	sortilin 1
chr5_+_68788387	0.481	NM_001205254	OCLN	occludin
chr2_-_192711651	0.480		SDPR	serum deprivation response
chr6_-_2972398	0.479	NM_001195291 NM_004568	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr21_+_41117333	0.478	NM_001080444	IGSF5	immunoglobulin superfamily, member 5
chr2_+_110656008	0.475	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr11_+_844445	0.473	NM_001025237	TSPAN4	tetraspanin 4
chr11_-_104916041	0.464	NM_001017534 NM_052889	CARD16	caspase recruitment domain family, member 16
chr2_+_47630246	0.459	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr5_-_42811959	0.456	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr2_-_192711923	0.455	NM_004657	SDPR	serum deprivation response
chr2_-_188419185	0.454	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_191878924	0.452	NM_007315 NM_139266	STAT1	signal transducer and activator of transcription 1, 91kDa
chr12_+_25205180	0.447	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr12_+_25205488	0.445		LRMP	lymphoid-restricted membrane protein
chr1_-_182357871	0.444		GLUL	glutamate-ammonia ligase
chr5_+_10353980	0.443
chr12_+_96588000	0.439	NM_005230	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chrX_-_133792497	0.437	NM_021796	PLAC1	placenta-specific 1
chr3_-_168865521	0.434	NM_001164000	MECOM	MDS1 and EVI1 complex locus
chr11_-_124180661	0.433	NM_001002917	OR8D1	olfactory receptor, family 8, subfamily D, member 1
chr17_+_7482980	0.431		CD68	CD68 molecule
chr2_-_45795104	0.428		SRBD1	S1 RNA binding domain 1
chr3_-_49851217	0.421		UBA7	ubiquitin-like modifier activating enzyme 7
chr14_+_65878579	0.421		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr7_-_86688944	0.419	NM_001142749	KIAA1324L	KIAA1324-like
chr8_-_93978264	0.419	NM_001191035 NM_001171795 NM_001171796 NM_001171797 NM_001171798 NM_001171799	C8orf83	chromosome 8 open reading frame 83
chr12_-_71031174	0.419	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr2_-_211018294	0.418		C2orf67	chromosome 2 open reading frame 67
chr19_+_39759153	0.417	NM_172138	IL28A	interleukin 28A (interferon, lambda 2)
chr1_-_203320185	0.415		FMOD	fibromodulin
chr1_-_203320287	0.415	NM_002023	FMOD	fibromodulin
chr7_+_80231503	0.411	NM_001001547	CD36	CD36 molecule (thrombospondin receptor)
chr18_+_29769986	0.408	NM_005925	MEP1B	meprin A, beta
chr20_+_43935490	0.405	NM_014276	RBPJL	recombination signal binding protein for immunoglobulin kappa J region-like
chr4_-_152096655	0.402	NM_001128924	SH3D19	SH3 domain containing 19
chr6_+_142623364	0.402		GPR126	G protein-coupled receptor 126
chr10_+_124320180	0.401	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr21_-_38444814	0.401	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr4_+_187148624	0.399	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr1_-_35920081	0.399		KIAA0319L	KIAA0319-like
chr17_+_72427535	0.398	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr20_+_31823801	0.395	NM_001243193 NM_016583 NM_130852	BPIFA1	BPI fold containing family A, member 1
chr1_+_61542928	0.395	NM_001145511	NFIA	nuclear factor I/A
chr19_-_41903226	0.393	NM_020158	EXOSC5	exosome component 5
chr3_-_98312384	0.389	NM_000097	CPOX	coproporphyrinogen oxidase
chr7_+_80267782	0.384	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr8_-_86253863	0.383	NM_001164830	CA1	carbonic anhydrase I

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.50	2.89e-03	GO:0007166	cell surface receptor linked signaling pathway
1.94	6.74e-03	GO:0050878	regulation of body fluid levels
2.06	7.56e-03	GO:0050776	regulation of immune response
1.47	8.56e-03	GO:0048583	regulation of response to stimulus
1.96	1.75e-02	GO:0007599	hemostasis
1.93	3.19e-02	GO:0007596	blood coagulation
1.93	3.19e-02	GO:0050817	coagulation
1.28	4.27e-02	GO:0023052	signaling

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.87	4.61e-05	GO:0005615	extracellular space
1.64	1.81e-03	GO:0044421	extracellular region part
1.23	2.97e-02	GO:0005886	plasma membrane
1.35	4.28e-02	GO:0005576	extracellular region
1.23	4.29e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.78	1.04e-02	GO:0005132	interferon-alpha/beta receptor binding
10.47	2.24e-02	GO:0004022	alcohol dehydrogenase (NAD) activity