Motif ID: GATA1..3.p2

Z-value: 1.270


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GATA1chrX_+_486449610.213.2e-01Click!
GATA2chr3_-_1282067040.116.0e-01Click!
GATA3chr10_+_8097350-0.106.2e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_22550057 1.692 NM_001199881
EGR3
early growth response 3
chr11_+_5410606 1.394 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr12_-_52779362 1.268 NM_033045
KRT84
keratin 84
chr6_-_114384008 1.168 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr16_+_3405888 1.143 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr19_+_15160194 1.051 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr9_+_35829375 1.050 NM_001042590
TMEM8B
transmembrane protein 8B
chrX_-_153236621 0.984 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr2_-_60780767 0.896 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr19_+_50145369 0.894 NM_021228
SCAF1
SR-related CTD-associated factor 1
chr2_+_162272892 0.884 TBR1
T-box, brain, 1
chr8_-_22550708 0.836 NM_004430
EGR3
early growth response 3
chr3_+_133494275 0.830 TF
transferrin
chr22_+_22385340 0.817


chr19_+_49376488 0.802 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr17_-_62050200 0.795 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr8_+_110099652 0.787 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr8_-_22549901 0.784 NM_001199880
EGR3
early growth response 3
chr2_-_31352489 0.771 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr16_+_89778242 0.751 LOC100128881
uncharacterized LOC100128881
chr19_+_39897457 0.737 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr8_+_22210311 0.711 PIWIL2
piwi-like 2 (Drosophila)
chr11_-_36619776 0.707 NM_000536
NM_001243785
NM_001243786
RAG2


recombination activating gene 2


chr1_-_153931077 0.703 CRTC2
CREB regulated transcription coactivator 2
chr11_-_9225780 0.688 DENND5A
DENN/MADD domain containing 5A
chr3_-_127541160 0.683 NM_007283
MGLL
monoglyceride lipase
chr6_-_29595746 0.678 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_+_132209354 0.668 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr2_-_69098502 0.663 NM_014482
BMP10
bone morphogenetic protein 10
chr9_+_35829208 0.648 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr11_-_64377332 0.646


chr1_+_27101217 0.629 ARID1A
AT rich interactive domain 1A (SWI-like)
chr11_-_16424391 0.628 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr1_+_212738675 0.624 NM_001030287
ATF3
activating transcription factor 3
chr1_-_153930911 0.618 CRTC2
CREB regulated transcription coactivator 2
chr5_+_137801166 0.607 EGR1
early growth response 1
chr17_+_7258454 0.601 NM_198154
TMEM95
transmembrane protein 95
chr20_+_16728997 0.594 NM_020157
OTOR
otoraplin
chr5_-_66492574 0.584 NM_005582
CD180
CD180 molecule
chr1_+_248058857 0.582 NM_001001957
OR2W3
olfactory receptor, family 2, subfamily W, member 3
chr17_-_1303402 0.579 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr20_-_44600939 0.578 ZNF335
zinc finger protein 335
chr1_-_151688791 0.568 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr3_-_57312979 0.554 NM_130387
ASB14
ankyrin repeat and SOCS box containing 14
chr6_+_123317377 0.541 CLVS2
clavesin 2
chr17_-_39646115 0.537 NM_003771
KRT36
keratin 36
chr6_+_123317579 0.534 NM_001010852
CLVS2
clavesin 2
chr3_+_31574431 0.533 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr12_+_57920425 0.531 MBD6
methyl-CpG binding domain protein 6
chr4_-_141489882 0.528 NM_021833
UCP1
uncoupling protein 1 (mitochondrial, proton carrier)
chr16_+_6533758 0.528 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr15_+_60296420 0.527 NM_012182
FOXB1
forkhead box B1
chr1_-_161601251 0.527 NM_001244753
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr1_+_31882411 0.526 NM_001199038
SERINC2
serine incorporator 2
chr8_+_125985538 0.525 NM_152412
ZNF572
zinc finger protein 572
chr12_-_9913415 0.523 NM_001781
CD69
CD69 molecule
chr12_+_50479033 0.522 SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_-_29297126 0.516 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr1_-_161519817 0.515 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr14_-_21899866 0.514 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr7_+_114055171 0.512 FOXP2
forkhead box P2
chr19_-_50316360 0.511 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr15_-_31947541 0.509 NM_130901
OTUD7A
OTU domain containing 7A
chr15_+_34261088 0.509 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr5_+_137801178 0.507 NM_001964
EGR1
early growth response 1
chr14_-_24047428 0.507 JPH4
junctophilin 4
chr2_-_96781887 0.507 NM_000682
ADRA2B
adrenergic, alpha-2B-, receptor
chr9_+_127420690 0.505 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr6_-_32143795 0.504 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_+_90033967 0.499 NM_145715
TIGD2
tigger transposable element derived 2
chr3_+_31574119 0.497 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr12_+_56075418 0.496 METTL7B
methyltransferase like 7B
chr17_-_48271365 0.496


chr3_-_108672547 0.495 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr12_-_122240827 0.492


chr5_-_146435589 0.489 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr6_-_29055048 0.488 NM_001005226
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr19_+_15838833 0.483 NM_013939
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr6_+_27777713 0.482 NM_003536
HIST1H3H
histone cluster 1, H3h
chr21_+_27012067 0.480 JAM2
junctional adhesion molecule 2
chr20_+_18794369 0.479 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr1_+_212788359 0.475 NM_001206486
ATF3
activating transcription factor 3
chrX_+_70364680 0.473 NM_001166660
NM_018977
NM_181303
NLGN3


neuroligin 3


chr17_-_27240982 0.472 PHF12
PHD finger protein 12
chrX_+_48368063 0.472 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr12_-_99548471 0.471 NM_001204068
NM_001204069
NM_001204070
NM_020140
NM_181670
NM_001204066
ANKS1B





ankyrin repeat and sterile alpha motif domain containing 1B





chr18_+_77659446 0.469


chr1_-_151689246 0.466 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr12_+_1738411 0.465 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr6_-_32160289 0.464 GPSM3
G-protein signaling modulator 3
chr5_-_1882764 0.463 NM_016358
IRX4
iroquois homeobox 4
chr1_-_149908759 0.461 NM_001145862
MTMR11
myotubularin related protein 11
chr1_-_153931096 0.460 NM_181715
CRTC2
CREB regulated transcription coactivator 2
chr1_+_209878135 0.460 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr19_+_46367517 0.459 NM_004497
FOXA3
forkhead box A3
chr5_+_175308843 0.459 CPLX2
complexin 2
chrX_-_110654373 0.459 NM_000555
DCX
doublecortin
chr1_-_247921707 0.458 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr6_-_32143886 0.458 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_+_81118639 0.457 NM_001099403
PRDM8
PR domain containing 8
chr6_-_62995852 0.457 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr13_-_33780142 0.455 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr7_+_103969103 0.453 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr4_-_21305528 0.453 NM_147183
KCNIP4
Kv channel interacting protein 4
chr11_-_72385411 0.451 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr7_+_39017608 0.449 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr1_-_26644755 0.447 NM_145345
UBXN11
UBX domain protein 11
chr17_-_1248346 0.444 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr17_-_39150384 0.444 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr1_+_47137496 0.442 NM_001145474
ATPAF1-AS1
ATPAF1 antisense RNA 1 (non-protein coding)
chr16_+_30709913 0.440


chrX_+_70364707 0.437 NLGN3
neuroligin 3
chr16_+_24802421 0.435 TNRC6A
trinucleotide repeat containing 6A
chr11_-_70858241 0.435 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr10_-_100995558 0.434 NM_001166244
NM_001166245
NM_001166246
NM_021828
HPSE2



heparanase 2



chr17_-_39280377 0.434 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr6_-_32143899 0.431 NM_006411
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr8_+_102504836 0.431 GRHL2
grainyhead-like 2 (Drosophila)
chr1_+_153232178 0.427 NM_000427
LOR
loricrin
chr15_-_72523542 0.425 PKM2
pyruvate kinase, muscle
chr4_+_69681709 0.425 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr12_+_94542239 0.425 NM_005761
PLXNC1
plexin C1
chr5_-_172755418 0.423 STC2
stanniocalcin 2
chrX_+_70364728 0.421 NLGN3
neuroligin 3
chrX_+_82763268 0.420 NM_000307
POU3F4
POU class 3 homeobox 4
chrX_+_49126480 0.419 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr19_-_51141301 0.414 NM_032298
SYT3
synaptotagmin III
chr16_+_67694795 0.413 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr20_-_1309809 0.411 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr6_-_119470336 0.410 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr2_+_169757749 0.410 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr15_-_72523483 0.409 PKM2
pyruvate kinase, muscle
chr9_+_131191206 0.408 CERCAM
cerebral endothelial cell adhesion molecule
chr9_-_34458477 0.408 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184945
NM_147202
C9orf25





chromosome 9 open reading frame 25





chr15_-_72523557 0.407 PKM2
pyruvate kinase, muscle
chr12_+_7033625 0.405 NM_001007026
ATN1
atrophin 1
chr17_+_42925278 0.404 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr5_+_156820161 0.402 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_-_149669187 0.400 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr16_+_29674564 0.398 SPN
sialophorin
chr12_+_81101407 0.397 NM_002469
MYF6
myogenic factor 6 (herculin)
chr18_+_55102777 0.397 NM_004852
ONECUT2
one cut homeobox 2
chr16_+_202853 0.397 NM_005332
HBZ
hemoglobin, zeta
chr16_-_28518131 0.396 NM_145659
IL27
interleukin 27
chr12_+_50478942 0.389 NM_003076
NM_139071
SMARCD1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

chr5_-_141993691 0.389 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr6_-_134639195 0.388 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_36861857 0.387 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr8_+_50824596 0.385 NM_018967
SNTG1
syntrophin, gamma 1
chr5_+_31193852 0.383 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr1_-_145715561 0.379 NM_007053
CD160
CD160 molecule
chr2_+_36923832 0.379 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr5_-_145895675 0.378 NM_194251
GPR151
G protein-coupled receptor 151
chr19_-_46272496 0.378 NM_175875
SIX5
SIX homeobox 5
chr8_+_65492794 0.377 NM_152414
BHLHE22
basic helix-loop-helix family, member e22
chr11_-_5173598 0.374 NM_012375
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr8_+_145064583 0.373 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_+_18474078 0.372 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr11_-_47399903 0.371


chr13_+_112721912 0.369 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr11_+_69455938 0.368 CCND1
cyclin D1
chr9_-_35115844 0.367 NM_025182
FAM214B
family with sequence similarity 214, member B
chr16_+_23847321 0.366 PRKCB
protein kinase C, beta
chr5_-_172198160 0.366 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_-_51259239 0.366 NRXN1
neurexin 1
chr19_+_15197790 0.365 NM_001004713
OR1I1
olfactory receptor, family 1, subfamily I, member 1
chr13_-_33859835 0.362 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_31380507 0.361 NM_022728
NEUROD6
neurogenic differentiation 6
chr16_-_67881360 0.357 NM_025082
CENPT
centromere protein T
chr2_-_74734498 0.355 PCGF1
polycomb group ring finger 1
chr15_+_60296506 0.354 FOXB1
forkhead box B1
chrX_+_128913897 0.353 SASH3
SAM and SH3 domain containing 3
chr11_-_120008219 0.353 TRIM29
tripartite motif containing 29
chr19_-_14224979 0.352 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr2_-_89619820 0.350 IGKC
immunoglobulin kappa constant
chr10_+_85933553 0.350 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr1_-_111743261 0.349 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr6_+_43265994 0.349 NM_006672
NM_153320
SLC22A7

solute carrier family 22 (organic anion transporter), member 7

chr17_-_48271968 0.348


chr16_-_27561216 0.347 GTF3C1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr19_+_50094911 0.346 NM_020719
PRR12
proline rich 12
chr18_-_28742744 0.345 NM_004948
NM_024421
DSC1

desmocollin 1

chr11_-_5345530 0.345 NM_033180
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr19_-_46295647 0.341 DMWD
dystrophia myotonica, WD repeat containing
chr6_+_31543340 0.341 NM_000594
TNF
tumor necrosis factor
chr12_-_99548867 0.341 NM_001204067
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr12_-_123380628 0.339 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr8_-_121824015 0.338


chr4_+_76481257 0.338 NM_001206981
NM_178497
C4orf26

chromosome 4 open reading frame 26

chr17_-_1303548 0.337 NM_006761
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr22_+_31478845 0.333 NM_001207017
SMTN
smoothelin
chr9_+_35560424 0.332 RUSC2
RUN and SH3 domain containing 2
chr9_-_35958095 0.332 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr19_-_54692132 0.331 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr7_+_141463896 0.329 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr20_-_44600787 0.328 NM_022095
ZNF335
zinc finger protein 335
chr20_+_327329 0.326 NM_024958
NRSN2
neurensin 2
chrX_+_41306686 0.324 NM_022567
NYX
nyctalopin
chr2_-_60780404 0.324 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr11_-_1017140 0.323 MUC6
mucin 6, oligomeric mucus/gel-forming

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 5.80e-14 GO:0048731 system development
1.27 2.15e-13 GO:0048856 anatomical structure development
1.25 1.04e-12 GO:0007275 multicellular organismal development
1.23 1.39e-12 GO:0023052 signaling
1.49 5.38e-12 GO:0007154 cell communication
1.23 6.52e-12 GO:0032502 developmental process
1.38 2.82e-11 GO:0007399 nervous system development
1.54 1.07e-10 GO:0007267 cell-cell signaling
1.30 6.67e-10 GO:0030154 cell differentiation
1.30 7.76e-10 GO:0048869 cellular developmental process
1.16 4.06e-09 GO:0032501 multicellular organismal process
1.21 2.67e-08 GO:0007165 signal transduction
1.07 2.94e-08 GO:0009987 cellular process
1.17 1.70e-07 GO:0051716 cellular response to stimulus
1.57 4.10e-07 GO:0019226 transmission of nerve impulse
1.57 4.10e-07 GO:0035637 multicellular organismal signaling
1.11 4.47e-07 GO:0050789 regulation of biological process
1.11 5.12e-07 GO:0065007 biological regulation
1.41 6.56e-07 GO:0022008 neurogenesis
1.58 2.32e-06 GO:0007268 synaptic transmission
1.11 3.01e-06 GO:0050794 regulation of cellular process
1.40 5.06e-06 GO:0048699 generation of neurons
1.29 8.41e-06 GO:0009653 anatomical structure morphogenesis
1.11 8.08e-05 GO:0050896 response to stimulus
1.23 1.44e-04 GO:0048513 organ development
1.23 1.66e-04 GO:0048583 regulation of response to stimulus
1.24 1.70e-04 GO:0007166 cell surface receptor linked signaling pathway
1.27 3.77e-04 GO:0009966 regulation of signal transduction
1.39 4.00e-04 GO:0030182 neuron differentiation
1.24 4.04e-04 GO:0023051 regulation of signaling
1.34 5.00e-04 GO:0006811 ion transport
1.30 6.25e-04 GO:0010646 regulation of cell communication
1.33 1.19e-03 GO:0009888 tissue development
1.17 1.55e-03 GO:0048518 positive regulation of biological process
1.30 3.19e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 3.51e-03 GO:0051239 regulation of multicellular organismal process
1.39 4.66e-03 GO:0048666 neuron development
1.18 6.27e-03 GO:0048519 negative regulation of biological process
1.31 8.32e-03 GO:0040011 locomotion
1.35 9.41e-03 GO:0010628 positive regulation of gene expression
1.43 1.01e-02 GO:0051094 positive regulation of developmental process
1.58 1.73e-02 GO:0030168 platelet activation
1.16 2.18e-02 GO:0048522 positive regulation of cellular process
1.33 2.31e-02 GO:0045595 regulation of cell differentiation
1.33 2.53e-02 GO:0009790 embryo development
1.31 2.69e-02 GO:2000026 regulation of multicellular organismal development
1.39 2.75e-02 GO:0030001 metal ion transport
1.76 3.04e-02 GO:0042391 regulation of membrane potential
1.36 3.15e-02 GO:0006812 cation transport
1.34 3.61e-02 GO:0030030 cell projection organization
1.28 3.63e-02 GO:0050793 regulation of developmental process
1.38 3.92e-02 GO:0048585 negative regulation of response to stimulus
1.38 4.47e-02 GO:0048858 cell projection morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.55 4.18e-06 GO:0045202 synapse
1.50 7.23e-05 GO:0043005 neuron projection
1.19 1.66e-04 GO:0044459 plasma membrane part
1.55 3.42e-04 GO:0044456 synapse part
1.30 8.66e-04 GO:0042995 cell projection
1.75 2.94e-03 GO:0034703 cation channel complex
1.59 3.44e-03 GO:0034702 ion channel complex
1.34 4.41e-03 GO:0030054 cell junction
1.19 2.62e-02 GO:0005856 cytoskeleton
1.63 3.10e-02 GO:0045211 postsynaptic membrane
1.10 3.15e-02 GO:0005886 plasma membrane
1.10 4.86e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 3.34e-10 GO:0005515 protein binding
1.51 5.52e-05 GO:0015267 channel activity
1.50 6.56e-05 GO:0022803 passive transmembrane transporter activity
1.37 7.52e-05 GO:0015075 ion transmembrane transporter activity
1.31 1.97e-04 GO:0022857 transmembrane transporter activity
1.56 2.79e-04 GO:0022836 gated channel activity
1.32 3.93e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.48 4.55e-04 GO:0022838 substrate-specific channel activity
1.48 5.38e-04 GO:0005216 ion channel activity
1.29 7.78e-04 GO:0022892 substrate-specific transporter activity
1.29 8.09e-04 GO:0001071 nucleic acid binding transcription factor activity
1.29 8.09e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 8.26e-04 GO:0030528 transcription regulator activity
1.05 1.65e-03 GO:0005488 binding
1.38 1.67e-03 GO:0008324 cation transmembrane transporter activity
1.25 2.37e-03 GO:0005215 transporter activity
1.33 4.02e-03 GO:0043565 sequence-specific DNA binding
1.70 9.51e-03 GO:0046873 metal ion transmembrane transporter activity
1.85 2.25e-02 GO:0015081 sodium ion transmembrane transporter activity
1.66 3.00e-02 GO:0022843 voltage-gated cation channel activity
1.46 4.58e-02 GO:0005261 cation channel activity