Motif ID: GCUGGUG

Z-value: 0.850


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_41362750 3.666 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr4_+_41614911 3.637 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr13_-_72441312 3.550 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr9_-_14398981 2.637 NM_001190738
NFIB
nuclear factor I/B
chr1_+_61542928 2.472 NM_001145511
NFIA
nuclear factor I/A
chr9_-_14314036 2.393 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr2_+_7057471 2.378 NM_014746
RNF144A
ring finger protein 144A
chr1_+_61547625 2.356 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61547388 2.211 NM_001145512
NFIA
nuclear factor I/A
chr8_+_37654395 2.174 NM_032777
GPR124
G protein-coupled receptor 124
chr6_+_136172802 1.469 NM_018945
PDE7B
phosphodiesterase 7B
chr4_+_87928083 1.169 NM_005935
AFF1
AF4/FMR2 family, member 1
chr2_-_240322620 1.143 NM_006037
HDAC4
histone deacetylase 4
chr6_+_15246299 1.131 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr13_-_101327102 1.040 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr9_+_115513050 0.999 NM_001012994
SNX30
sorting nexin family member 30
chr20_+_306205 0.973 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr9_-_111882209 0.951 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr12_+_20522178 0.940 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr5_+_153570270 0.915 NM_198321
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_-_14316980 0.913 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr5_+_121647773 0.904 NM_001242935
NM_005460
SNCAIP

synuclein, alpha interacting protein

chr7_+_130126035 0.901 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr8_-_81787015 0.886 NM_001033723
ZNF704
zinc finger protein 704
chr3_-_56809594 0.881 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr3_-_57113292 0.873 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr4_-_186697065 0.857 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr4_+_87856152 0.856 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr15_+_57210823 0.848 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr4_-_186733372 0.843 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr4_-_186732047 0.835 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr2_+_86947387 0.831 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr7_-_30029904 0.820 NM_001145514
SCRN1
secernin 1
chr4_-_186732208 0.816 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr3_-_56835829 0.807 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr4_-_186877869 0.797 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr11_-_130184459 0.788 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr7_-_30029284 0.786 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr13_+_35516390 0.777 NM_015678
NBEA
neurobeachin
chr4_+_159131400 0.777 NM_018342
TMEM144
transmembrane protein 144
chr14_+_66974124 0.766 NM_001024218
NM_020806
GPHN

gephyrin

chr20_+_10199455 0.757 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chrX_+_73641084 0.757 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr13_-_52585472 0.757 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr7_-_132261268 0.756 NM_001105543
NM_020911
PLXNA4

plexin A4

chr15_-_56035176 0.745 NM_173814
PRTG
protogenin
chr15_+_57511616 0.724 NM_207040
TCF12
transcription factor 12
chr7_+_130131172 0.720 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr17_+_38474472 0.719 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr7_+_130131921 0.717 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr18_-_53255734 0.716 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr17_+_18164423 0.714 NM_148886
SMCR7
Smith-Magenis syndrome chromosome region, candidate 7
chr13_+_36050885 0.699 NM_001204197
NBEA
neurobeachin
chr6_-_41909386 0.687 NM_001136125
NM_001760
CCND3

cyclin D3

chr20_-_36156082 0.673 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr6_+_107811272 0.672 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr6_+_87865261 0.669 NM_015021
ZNF292
zinc finger protein 292
chr2_+_109237679 0.647 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_204042191 0.644 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr20_-_36156282 0.636 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr6_-_42016609 0.633 NM_001136017
NM_001136126
CCND3

cyclin D3

chr8_-_52811707 0.627 NM_052937
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr2_+_109150807 0.626 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr20_+_54933982 0.623 NM_080821
FAM210B
family with sequence similarity 210, member B
chr10_+_80828776 0.623 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr1_+_33004771 0.610 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr20_-_36152952 0.596 NM_001167823
BLCAP
bladder cancer associated protein
chr1_+_116185249 0.593 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr2_+_109204745 0.591 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_-_111136407 0.581 NM_015076
CDK19
cyclin-dependent kinase 19
chr7_+_8008416 0.578 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr2_+_109271267 0.573 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_186578122 0.567 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr2_+_113403433 0.567 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr2_+_109223600 0.562 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_+_38465422 0.556 NM_000964
RARA
retinoic acid receptor, alpha
chr20_-_35488275 0.545 NM_199181
KIAA0889
KIAA0889
chr12_+_32654976 0.534 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_-_43453737 0.534 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr2_-_85788644 0.528 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr1_+_116184573 0.526 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr17_+_7743233 0.521 NM_001080424
KDM6B
lysine (K)-specific demethylase 6B
chr11_-_78052925 0.521 NM_012296
GAB2
GRB2-associated binding protein 2
chr4_-_42658883 0.517 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr1_-_92371558 0.503 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr17_+_18163836 0.500 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chrX_+_152954965 0.495 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr16_+_58549382 0.491 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr3_-_13114547 0.487 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr1_-_92351613 0.479 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr20_+_42086468 0.477 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr2_+_109204904 0.475 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr13_-_74707913 0.471 NM_007249
KLF12
Kruppel-like factor 12
chr2_+_217498082 0.466 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_-_208084432 0.466 NM_001025109
NM_001773
CD34

CD34 molecule

chr2_-_160472960 0.466 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr7_+_73507485 0.464 NM_001204426
LIMK1
LIM domain kinase 1
chr20_+_36531498 0.462 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr1_+_178694273 0.454 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr7_+_128864740 0.452 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr6_+_39760148 0.437 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_+_210406194 0.432 NM_019605
SERTAD4
SERTA domain containing 4
chr19_+_19496629 0.428 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chr2_-_97535669 0.426 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_-_49337370 0.423 NM_017643
MBTD1
mbt domain containing 1
chr11_-_78128852 0.419 NM_080491
GAB2
GRB2-associated binding protein 2
chr2_+_85581840 0.419 NM_001135021
NM_001135022
NM_001135023
NM_032213
ELMOD3



ELMO/CED-12 domain containing 3



chr7_+_89840999 0.418 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr17_+_27920479 0.417 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr6_+_41514133 0.416 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr6_-_39895317 0.414 NM_005943
MOCS1
molybdenum cofactor synthesis 1
chr7_-_148580600 0.412 NM_001203249
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr17_-_37557851 0.407 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr18_+_8717368 0.407 NM_015210
CCDC165
coiled-coil domain containing 165
chr10_+_129705299 0.404 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_+_69644341 0.400 NM_012238
SIRT1
sirtuin 1
chr1_+_26872342 0.399 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr10_+_69644938 0.396 NM_001142498
SIRT1
sirtuin 1
chr8_-_135708789 0.393 NM_001029939
NM_001167583
NM_001174158
ZFAT


zinc finger and AT hook domain containing


chr5_+_154238196 0.392 NM_004779
CNOT8
CCR4-NOT transcription complex, subunit 8
chr8_-_135725204 0.391 NM_001174157
NM_020863
ZFAT

zinc finger and AT hook domain containing

chr1_-_153895450 0.391 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chrX_-_109561314 0.390 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr6_+_35310317 0.387 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr19_+_47421932 0.385 NM_004491
ARHGAP35
Rho GTPase activating protein 35
chr3_-_13008959 0.383 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr11_-_65381641 0.382 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr4_-_2263706 0.381 NM_006454
MXD4
MAX dimerization protein 4
chr2_+_28615771 0.380 NM_005253
FOSL2
FOS-like antigen 2
chr14_+_77228132 0.377 NM_014909
VASH1
vasohibin 1
chr9_-_101558494 0.369 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr6_+_158957467 0.368 NM_020823
TMEM181
transmembrane protein 181
chr2_+_113033146 0.363 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr2_+_219263060 0.362 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_-_2304217 0.362 NM_020310
MNT
MAX binding protein
chrX_+_152953751 0.362 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr10_-_64578926 0.360 NM_001136178
EGR2
early growth response 2
chr2_+_148602569 0.358 NM_001616
ACVR2A
activin A receptor, type IIA
chr20_+_36661849 0.356 NM_021215
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr15_+_52043738 0.356 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr7_-_148581403 0.355 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr11_+_12695851 0.353 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr9_-_131940538 0.352 NM_203434
IER5L
immediate early response 5-like
chr10_-_12085022 0.351 NM_080599
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr7_+_129007942 0.347 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr10_-_64576123 0.344 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr5_+_139175385 0.340 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr1_+_26856240 0.339 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_110693131 0.339 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr10_+_129845806 0.338 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_11862955 0.336 NM_017944
USP47
ubiquitin specific peptidase 47
chr15_-_52587851 0.333 NM_018728
MYO5C
myosin VC
chr10_+_76586299 0.332 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr20_-_3388219 0.330 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr12_+_48357325 0.327 NM_001143841
NM_001143842
NM_001143843
NM_024056
TMEM106C



transmembrane protein 106C



chr1_+_93544786 0.326 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr18_+_46065367 0.322 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr15_+_49170264 0.314 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr3_+_51705221 0.314 NM_001129884
NM_001243727
NM_015926
NM_001243725
NM_001243726
TEX264




testis expressed 264




chr15_+_75941347 0.311 NM_153271
SNX33
sorting nexin 33
chr16_+_69220940 0.309 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr13_+_42846255 0.308 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr13_-_67804432 0.304 NM_020403
NM_203487
PCDH9

protocadherin 9

chr14_+_104605059 0.299 NM_015656
KIF26A
kinesin family member 26A
chr2_+_219264477 0.299 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr11_-_85376159 0.298 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr12_+_111843743 0.291 NM_005475
SH2B3
SH2B adaptor protein 3
chr17_-_71088832 0.289 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr3_+_156392714 0.289 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr20_-_47444404 0.284 NM_020820
PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr3_+_23987514 0.284 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr19_+_54960064 0.283 NM_052925
LENG8
leukocyte receptor cluster (LRC) member 8
chr15_-_43877043 0.278 NM_014659
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_+_40839368 0.278 NM_022733
SMAP2
small ArfGAP2
chr20_+_32077904 0.276 NM_001032999
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr6_+_39760772 0.276 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_109935869 0.272 NM_001205228
SORT1
sortilin 1
chr9_+_130911731 0.272 NM_005564
LCN2
lipocalin 2
chrX_-_24690740 0.269 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_-_39968450 0.267 NM_006455
LEPREL4
leprecan-like 4
chrX_-_24665454 0.267 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr10_-_12084772 0.266 NM_015542
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr5_-_73937248 0.262 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr1_+_20208837 0.261 NM_015207
OTUD3
OTU domain containing 3
chr6_+_130339715 0.261 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr12_-_30848805 0.260 NM_006390
IPO8
importin 8
chr6_-_39902140 0.256 NM_001075098
MOCS1
molybdenum cofactor synthesis 1
chr9_+_706744 0.254 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chrX_-_50557019 0.253 NM_020717
SHROOM4
shroom family member 4
chr1_-_22263676 0.253 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr12_-_30830143 0.252 NM_001190995
IPO8
importin 8
chr11_+_134094545 0.251 NM_052875
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr7_-_99006275 0.250 NM_014891
PDAP1
PDGFA associated protein 1
chr5_-_90679115 0.248 NM_020801
ARRDC3
arrestin domain containing 3
chr3_-_125094003 0.248 NM_021964
ZNF148
zinc finger protein 148
chr18_-_45663667 0.248 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr1_-_20812727 0.245 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_+_26438267 0.245 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr12_+_132195632 0.244 NM_004592
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr11_-_128894008 0.244 NM_014715
ARHGAP32
Rho GTPase activating protein 32

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.53 3.77e-02 GO:0044456 synapse part
21.84 4.98e-02 GO:0014731 spectrin-associated cytoskeleton

Nothing significant found in function category.