Motif ID: GFI1B.p2

Z-value: 0.509


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GFI1Bchr9_+_135854097-0.193.6e-01Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_157189040 0.960 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr5_-_88179278 0.582 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr4_+_166248816 0.579 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr21_-_47648715 0.561 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr7_+_63773185 0.525 NM_001170905
ZNF736
zinc finger protein 736
chr21_-_47648672 0.512 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr21_-_47648685 0.485 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr3_-_187454247 0.463 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr17_-_56494930 0.419 NM_017763
RNF43
ring finger protein 43
chr9_+_12693385 0.419 NM_000550
TYRP1
tyrosinase-related protein 1
chr4_+_154125589 0.407 NM_015271
TRIM2
tripartite motif containing 2
chr3_-_112359565 0.406 CCDC80
coiled-coil domain containing 80
chr3_-_112359660 0.400 CCDC80
coiled-coil domain containing 80
chr8_-_124544376 0.385 NM_148177
FBXO32
F-box protein 32
chr3_-_112359863 0.384 CCDC80
coiled-coil domain containing 80
chr3_-_112359962 0.383 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr3_+_133494275 0.372 TF
transferrin
chr3_-_112359547 0.360 CCDC80
coiled-coil domain containing 80
chr1_+_162760491 0.349 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr5_+_140792507 0.331 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr15_+_62359175 0.330 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr12_-_8815479 0.328 MFAP5
microfibrillar associated protein 5
chr1_+_164528914 0.326 PBX1
pre-B-cell leukemia homeobox 1
chr10_-_91011516 0.318 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr4_+_42399855 0.307 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr3_-_187452669 0.295 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr7_-_82073020 0.286 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr10_+_74653338 0.285 NM_152635
OIT3
oncoprotein induced transcript 3
chr10_-_91011562 0.284 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr12_+_113229548 0.283 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr1_+_66798095 0.261 PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_+_26217145 0.261 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr2_-_113542970 0.260 NM_000575
IL1A
interleukin 1, alpha
chr6_-_31648140 0.259 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr4_+_41540187 0.258 LIMCH1
LIM and calponin homology domains 1
chr3_-_158390266 0.254 NM_020169
LXN
latexin
chr15_-_42448769 0.254 NM_213600
PLA2G4F
phospholipase A2, group IVF
chrX_-_57936853 0.252 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr11_+_111789600 0.243 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr7_+_28475233 0.242 NM_004904
CREB5
cAMP responsive element binding protein 5
chr7_-_112727799 0.239 GPR85
G protein-coupled receptor 85
chr8_-_19540093 0.234 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_-_91793375 0.234 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr11_-_71746966 0.234


chrX_-_10588458 0.228 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr7_-_56101830 0.220 PSPH
phosphoserine phosphatase
chr11_-_102595623 0.213 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr15_+_38544119 0.210 SPRED1
sprouty-related, EVH1 domain containing 1
chr1_+_101702304 0.203 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_133748828 0.201 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr6_+_90272036 0.200 NM_001242811
ANKRD6
ankyrin repeat domain 6
chr2_+_176987412 0.197 NM_014213
HOXD9
homeobox D9
chr1_+_101702561 0.195 S1PR1
sphingosine-1-phosphate receptor 1
chr7_+_28448970 0.193 LOC401317
uncharacterized LOC401317
chr4_-_186877869 0.187 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr7_-_112727778 0.182 GPR85
G protein-coupled receptor 85
chr8_-_93029864 0.177 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_105757592 0.175 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr1_+_84647342 0.175 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_88119604 0.174 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr10_-_91403630 0.173 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr19_+_11200124 0.169 LDLR
low density lipoprotein receptor
chrX_-_103268231 0.167 NM_001002916
H2BFWT
H2B histone family, member W, testis-specific
chr4_-_186733372 0.163 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chrX_+_16141423 0.162 NM_005314
GRPR
gastrin-releasing peptide receptor
chr13_+_111855406 0.162 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_+_6566153 0.160 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chrX_-_21676416 0.156 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr3_-_64211111 0.155 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_-_64727608 0.154 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr7_-_113559048 0.151 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr4_-_186577858 0.150 SORBS2
sorbin and SH3 domain containing 2
chr15_-_40599872 0.148 PLCB2
phospholipase C, beta 2
chr11_-_67290798 0.147 NM_016366
CABP2
calcium binding protein 2
chrX_-_33146543 0.147 NM_004010
NM_004009
DMD

dystrophin

chr5_+_68800003 0.146 NM_001205255
OCLN
occludin
chr5_+_109025135 0.144 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr7_+_134832765 0.141 NM_018295
TMEM140
transmembrane protein 140
chr2_+_33701678 0.141 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_+_53479685 0.140 RBL2
retinoblastoma-like 2 (p130)
chr1_+_66797775 0.139 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_-_22297729 0.138 NM_000948
PRL
prolactin
chrX_-_54069593 0.138 NM_001184898
PHF8
PHD finger protein 8
chr11_+_75273245 0.138 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_+_124120422 0.135 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr17_-_26127474 0.133 NM_000625
NOS2
nitric oxide synthase 2, inducible
chr7_-_82072804 0.132 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr22_+_22735202 0.130


chr19_+_41770329 0.129 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr5_+_31532372 0.126 NM_018356
C5orf22
chromosome 5 open reading frame 22
chr19_+_41770285 0.125 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr1_+_150337145 0.124 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chrX_-_13835012 0.123 GPM6B
glycoprotein M6B
chr5_+_140729723 0.123 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr3_+_113557679 0.122 NM_017577
GRAMD1C
GRAM domain containing 1C
chr14_-_24047428 0.121 JPH4
junctophilin 4
chr17_-_56494889 0.121 RNF43
ring finger protein 43
chrX_+_17393806 0.119 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chrX_-_120066150 0.119 NM_001242922
NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A12
CT47A11
CT47A10
CT47A9
CT47A8
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A12
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr4_+_41540320 0.119 LIMCH1
LIM and calponin homology domains 1
chr6_-_144329342 0.117 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr15_-_40600118 0.117 NM_004573
PLCB2
phospholipase C, beta 2
chr20_+_31755882 0.116 NM_080574
BPIFA2
BPI fold containing family A, member 2
chr5_+_173472737 0.115 HMP19
HMP19 protein
chr19_-_14530129 0.110 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr10_+_118305427 0.108 NM_000936
PNLIP
pancreatic lipase
chr6_-_138820578 0.108 NM_001144060
NHSL1
NHS-like 1
chr20_-_39317875 0.107 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr10_+_69644341 0.107 NM_012238
SIRT1
sirtuin 1
chr11_-_62752370 0.105 NM_004790
NM_153276
NM_153277
NM_153278
SLC22A6



solute carrier family 22 (organic anion transporter), member 6



chr1_+_57320442 0.105 NM_000562
C8A
complement component 8, alpha polypeptide
chr19_+_11200146 0.104 LDLR
low density lipoprotein receptor
chr18_-_22930826 0.104


chr19_-_56739658 0.102 NM_024303
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr19_-_14530155 0.102 NM_005804
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr3_+_188889762 0.102 NM_198485
TPRG1
tumor protein p63 regulated 1
chr10_+_89267589 0.101 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr3_+_98072697 0.101 NM_001005517
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr9_-_73029539 0.101 NM_001206
KLF9
Kruppel-like factor 9
chr16_+_8807186 0.100 ABAT
4-aminobutyrate aminotransferase
chr7_-_112727832 0.099 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr11_+_112046207 0.099 NM_031938
BCO2
beta-carotene oxygenase 2
chr1_+_33283193 0.099 S100PBP
S100P binding protein
chr2_+_33738941 0.098 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrY_+_14774201 0.098 TTTY15
testis-specific transcript, Y-linked 15 (non-protein coding)
chr17_+_28268622 0.098 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr1_+_212475147 0.097 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chrX_+_57618440 0.097 ZXDB
zinc finger, X-linked, duplicated B
chr6_-_167040659 0.097 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_+_28452143 0.096 NM_182898
CREB5
cAMP responsive element binding protein 5
chr4_+_88529680 0.095 NM_014208
DSPP
dentin sialophosphoprotein
chr6_-_32920812 0.095 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr17_-_26127395 0.094 NOS2
nitric oxide synthase 2, inducible
chr18_+_11981421 0.092 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chrX_+_17393877 0.092 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr5_-_177423242 0.091 NM_006261
PROP1
PROP paired-like homeobox 1
chr8_+_68864341 0.089 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr16_+_71560022 0.086 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr11_+_65266980 0.085


chr1_-_27816667 0.084 WASF2
WAS protein family, member 2
chr1_-_17308072 0.083 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr3_+_15247743 0.082 CAPN7
calpain 7
chr1_+_61869699 0.082 NFIA
nuclear factor I/A
chr12_-_6233684 0.082 NM_000552
VWF
von Willebrand factor
chr15_+_100173182 0.082 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr1_-_179112178 0.082 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr10_-_91011586 0.082 NM_000235
NM_001127605
LIPA

lipase A, lysosomal acid, cholesterol esterase

chr4_+_74702272 0.081 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr19_+_41770349 0.081 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_-_118135197 0.081 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chrX_+_17393349 0.079 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr9_+_6215785 0.079 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr20_-_3065335 0.079 NM_000490
AVP
arginine vasopressin
chr18_-_40857245 0.079 NM_020783
SYT4
synaptotagmin IV
chr8_+_1993157 0.079 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr7_-_99332715 0.077 NM_000765
CYP3A7
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 7
cytochrome P450, family 3, subfamily A, polypeptide 5
chr1_+_220960038 0.076 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr2_+_132285469 0.076 NM_138770
CCDC74A
coiled-coil domain containing 74A
chr2_-_69180011 0.075 NM_182536
GKN2
gastrokine 2
chr4_+_15471488 0.075 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr14_-_20774129 0.074 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr16_+_28891234 0.074 ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr2_-_73460326 0.073 NM_032319
PRADC1
protease-associated domain containing 1
chr16_-_75301950 0.073 NM_001170715
BCAR1
breast cancer anti-estrogen resistance 1
chr14_-_68162419 0.072 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr19_+_19303007 0.071 NM_003721
NM_134440
RFXANK

regulatory factor X-associated ankyrin-containing protein

chr19_+_39155209 0.071


chr10_+_38645293 0.070 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr1_-_27816542 0.070 WASF2
WAS protein family, member 2
chr11_+_71900601 0.070 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr6_+_37252166 0.069 TBC1D22B
TBC1 domain family, member 22B
chrX_+_100805415 0.069 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr11_+_61717355 0.069 NM_001139443
NM_004183
BEST1

bestrophin 1

chr13_+_97928414 0.069 MBNL2
muscleblind-like 2 (Drosophila)
chr7_-_16505292 0.068 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_-_118472178 0.068 GDAP2
ganglioside induced differentiation associated protein 2
chr1_+_210001351 0.067 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr21_+_47269874 0.067 NM_001130141
NM_020528
PCBP3

poly(rC) binding protein 3

chr21_-_35899046 0.067 NM_203418
RCAN1
regulator of calcineurin 1
chrX_+_46696424 0.067 RP2
retinitis pigmentosa 2 (X-linked recessive)
chr1_-_153085963 0.066 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr10_+_37414784 0.065 NM_052997
ANKRD30A
ankyrin repeat domain 30A
chr5_+_134209426 0.065 NM_024715
TXNDC15
thioredoxin domain containing 15
chr2_+_163200582 0.063 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr22_-_43036606 0.063 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_-_204135420 0.063 NM_000537
REN
renin
chr3_-_33700932 0.063 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr1_-_151804225 0.063 NM_005060
RORC
RAR-related orphan receptor C
chr14_+_39735500 0.063 NM_001247988
NM_203356
CTAGE5

CTAGE family, member 5

chr18_-_24722757 0.063 NM_001243848
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr4_+_6271588 0.063 WFS1
Wolfram syndrome 1 (wolframin)
chr7_-_142630819 0.062 NM_019841
TRPV5
transient receptor potential cation channel, subfamily V, member 5
chr19_-_44123732 0.062 ZNF428
zinc finger protein 428
chr4_+_6271558 0.061 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr3_+_98451537 0.060 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr4_-_176734181 0.059 NM_201591
GPM6A
glycoprotein M6A
chr5_-_31532164 0.059 NM_001100412
NM_013235
DROSHA

drosha, ribonuclease type III

chr5_+_102201526 0.058 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr5_+_42756919 0.058 NM_001134848
CCDC152
coiled-coil domain containing 152
chr12_-_52761254 0.057 NM_002283
KRT85
keratin 85

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.