Motif ID: GTF2I.p2

Z-value: 1.999


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GTF2Ichr7_+_740720380.792.7e-06Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_16900348 22.598 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr4_-_16900028 21.863 LDB2
LIM domain binding 2
chr4_-_16900256 20.907 LDB2
LIM domain binding 2
chr14_-_54423448 9.659 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr8_-_22549901 8.660 NM_001199880
EGR3
early growth response 3
chr13_-_72441312 8.592 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr18_-_22930826 7.792


chr11_+_125034558 7.104 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr7_+_30951414 6.944 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr5_-_81046858 6.212 SSBP2
single-stranded DNA binding protein 2
chr8_-_22550057 6.195 NM_001199881
EGR3
early growth response 3
chr11_+_125034604 6.158 PKNOX2
PBX/knotted 1 homeobox 2
chr13_+_58205943 6.020 PCDH17
protocadherin 17
chr13_+_58205788 5.795 NM_001040429
PCDH17
protocadherin 17
chr14_-_54421269 5.573 NM_130851
BMP4
bone morphogenetic protein 4
chr5_-_81046943 5.493 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr4_-_102268626 5.243 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr1_+_164528586 5.202 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr9_+_133971862 5.184 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr11_-_33890931 5.089 LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_40913233 4.887 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr3_+_37903643 4.857 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr7_+_94024201 4.815 COL1A2
collagen, type I, alpha 2
chr1_-_92351476 4.538 TGFBR3
transforming growth factor, beta receptor III
chr5_-_111093030 4.499 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr9_+_133971902 4.438 AIF1L
allograft inflammatory factor 1-like
chr8_-_93115453 4.297 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr11_-_33891361 4.226 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_33891258 4.057 LMO2
LIM domain only 2 (rhombotin-like 1)
chr14_-_91526912 3.776 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr5_-_111092918 3.683 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_+_139028025 3.679 NM_016463
CXXC5
CXXC finger protein 5
chr12_+_93771607 3.538 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr13_-_114538953 3.501 NM_001143945
GAS6
growth arrest-specific 6
chr8_+_27491460 3.483 NM_016240
NM_182826
SCARA3

scavenger receptor class A, member 3

chr5_+_137801166 3.442 EGR1
early growth response 1
chr5_+_139028483 3.415 CXXC5
CXXC finger protein 5
chr3_+_20081853 3.412 KAT2B
K(lysine) acetyltransferase 2B
chr18_+_42260774 3.361 NM_015559
SETBP1
SET binding protein 1
chrX_+_152760452 3.349 BGN
biglycan
chr4_-_102268333 3.349 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_+_152760346 3.292 NM_001711
BGN
biglycan
chr19_-_41859519 3.257 TGFB1
transforming growth factor, beta 1
chr11_-_33891485 3.160 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr8_-_22550708 3.157 NM_004430
EGR3
early growth response 3
chr3_-_18466759 3.143 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr2_+_148778573 3.122 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr1_-_92351613 3.115 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr8_-_9008138 3.007 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr4_+_30721865 2.956 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr8_-_93107881 2.950 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr12_+_93964801 2.935 SOCS2
suppressor of cytokine signaling 2
chr15_-_82338459 2.900 MEX3B
mex-3 homolog B (C. elegans)
chr11_-_2160199 2.888 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr15_-_82338348 2.882 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr22_-_37584254 2.876 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr5_-_111092865 2.858 C5orf13
chromosome 5 open reading frame 13
chr19_-_41859830 2.830 NM_000660
TGFB1
transforming growth factor, beta 1
chr19_-_14201230 2.791 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr7_+_94023872 2.768 NM_000089
COL1A2
collagen, type I, alpha 2
chr8_-_93107442 2.741 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr3_+_20081523 2.736 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr15_-_69113089 2.706 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_150690838 2.668 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr8_+_37654757 2.608 GPR124
G protein-coupled receptor 124
chr1_-_20812727 2.562 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr8_+_97506141 2.559 SDC2
syndecan 2
chr6_-_16761600 2.551 NM_000332
NM_001128164
ATXN1

ataxin 1

chr1_+_47489239 2.513 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr1_+_211432855 2.498 RCOR3
REST corepressor 3
chrX_+_54834775 2.497 NM_014599
MAGED2
melanoma antigen family D, 2
chrX_-_54522318 2.488 NM_004463
FGD1
FYVE, RhoGEF and PH domain containing 1
chr9_-_14314036 2.486 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr16_+_55542909 2.480 NM_017839
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr8_+_37654833 2.476 GPR124
G protein-coupled receptor 124
chr4_-_102267952 2.469 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_-_33623771 2.462 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr5_+_68788387 2.451 NM_001205254
OCLN
occludin
chr5_+_139027907 2.435 CXXC5
CXXC finger protein 5
chr19_-_41859332 2.433 TGFB1
transforming growth factor, beta 1
chr19_-_291168 2.428 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chrX_-_63005212 2.399 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_+_101967290 2.338 GPRASP2
G protein-coupled receptor associated sorting protein 2
chr2_+_200323088 2.334


chr1_+_211432726 2.306 RCOR3
REST corepressor 3
chr4_+_100871625 2.293 LOC256880
uncharacterized LOC256880
chr5_+_139027955 2.287 CXXC5
CXXC finger protein 5
chr9_+_2015218 2.284 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr1_+_210406194 2.254 NM_019605
SERTAD4
SERTA domain containing 4
chr1_+_211432693 2.232 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr10_-_131762017 2.221 NM_001005463
EBF3
early B-cell factor 3
chr2_-_136873740 2.207 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr5_+_139027868 2.182 CXXC5
CXXC finger protein 5
chr1_+_211432732 2.181 RCOR3
REST corepressor 3
chrX_-_119694719 2.180 NM_001079872
CUL4B
cullin 4B
chr2_+_48757292 2.168 NM_001198595
NM_006873
STON1

stonin 1

chr8_+_97505895 2.160 SDC2
syndecan 2
chr1_+_87794576 2.153 LMO4
LIM domain only 4
chr17_+_40913211 2.135 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr4_+_41540187 2.133 LIMCH1
LIM and calponin homology domains 1
chr1_-_33168356 2.128 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr9_-_14086901 2.083 NFIB
nuclear factor I/B
chr11_-_67141008 2.080 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr12_+_53442732 2.070 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr5_-_111093251 2.044 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr16_+_29817810 2.040 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr11_-_130184459 2.033 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr17_-_49337370 2.031 NM_017643
MBTD1
mbt domain containing 1
chr8_-_38325524 2.019 FGFR1
fibroblast growth factor receptor 1
chr9_-_16870719 2.015 NM_017637
BNC2
basonuclin 2
chr4_-_114682836 1.977 NM_001221
NM_172114
NM_172115
NM_172127
NM_172128
NM_172129
CAMK2D





calcium/calmodulin-dependent protein kinase II delta





chr2_+_182756665 1.977 SSFA2
sperm specific antigen 2
chr8_+_97506020 1.975 SDC2
syndecan 2
chrX_-_119694871 1.950 CUL4B
cullin 4B
chr17_+_60705051 1.950 MRC2
mannose receptor, C type 2
chrX_-_54521866 1.945 FGD1
FYVE, RhoGEF and PH domain containing 1
chr8_+_97506071 1.932 SDC2
syndecan 2
chr9_-_14313899 1.928 NFIB
nuclear factor I/B
chr2_-_39664430 1.924 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr10_-_126849556 1.905 NM_001083914
CTBP2
C-terminal binding protein 2
chr12_+_56915587 1.900 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr11_-_2159472 1.893 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_60705042 1.892 MRC2
mannose receptor, C type 2
chr2_-_61697899 1.864 USP34
ubiquitin specific peptidase 34
chr6_-_32157511 1.860 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr1_+_32538497 1.840 NM_018056
TMEM39B
transmembrane protein 39B
chr18_+_46065367 1.831 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr2_-_218843541 1.830 TNS1
tensin 1
chr8_+_27491384 1.821 SCARA3
scavenger receptor class A, member 3
chr19_-_49149252 1.806 NM_001217
CA11
carbonic anhydrase XI
chr19_-_291335 1.799 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr2_-_152684689 1.791 ARL5A
ADP-ribosylation factor-like 5A
chr11_-_27741192 1.781 NM_001143807
BDNF
brain-derived neurotrophic factor
chrX_-_70475046 1.748 NM_001171162
ZMYM3
zinc finger, MYM-type 3
chr2_-_165478357 1.747 NM_004490
GRB14
growth factor receptor-bound protein 14
chrX_-_117250624 1.737 NM_001168302
NM_001168303
KLHL13

kelch-like 13 (Drosophila)

chr17_+_65821625 1.735 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr8_+_28747885 1.733 NM_001135726
HMBOX1
homeobox containing 1
chr19_-_2015628 1.721 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr19_+_50016435 1.713 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_+_159313466 1.712 NM_001005476
NM_003628
PKP4

plakophilin 4

chr17_+_38278789 1.711 NM_001012241
MSL1
male-specific lethal 1 homolog (Drosophila)
chr4_-_18023358 1.708 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr7_+_106685007 1.697 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr2_-_165477986 1.694 GRB14
growth factor receptor-bound protein 14
chr17_+_7788094 1.692 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr1_-_20812271 1.690 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_+_32538521 1.687 TMEM39B
transmembrane protein 39B
chr18_-_53255361 1.685 TCF4
transcription factor 4
chr11_-_71752099 1.680 NUMA1
nuclear mitotic apparatus protein 1
chr2_-_152684933 1.680 ARL5A
ADP-ribosylation factor-like 5A
chr15_+_57668702 1.673 NM_001252335
NM_032866
CGNL1

cingulin-like 1

chr2_-_152684963 1.671 NM_001037174
NM_012097
NM_177985
ARL5A


ADP-ribosylation factor-like 5A


chr12_+_57482674 1.671 NM_005967
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr5_+_137801178 1.664 NM_001964
EGR1
early growth response 1
chr10_-_126849066 1.656 NM_001329
CTBP2
C-terminal binding protein 2
chr4_-_114682594 1.655 CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr2_-_152684882 1.648 ARL5A
ADP-ribosylation factor-like 5A
chr16_-_30107492 1.645 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr22_+_51113069 1.643 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr2_-_165477818 1.637 GRB14
growth factor receptor-bound protein 14
chr8_-_141467853 1.634 NM_001160372
TRAPPC9
trafficking protein particle complex 9
chr15_-_37392322 1.632 MEIS2
Meis homeobox 2
chr2_+_189156730 1.613 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_78511588 1.611 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr19_-_41859253 1.609 TGFB1
transforming growth factor, beta 1
chr14_-_76127526 1.606 NM_007176
C14orf1
chromosome 14 open reading frame 1
chr1_+_87797371 1.603 LMO4
LIM domain only 4
chr19_-_14316980 1.602 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr12_+_57482886 1.599 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr15_-_37392358 1.593 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chrX_-_101186976 1.585 NM_001011657
ZMAT1
zinc finger, matrin-type 1
chr4_+_42399855 1.577 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr12_-_53893195 1.569 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr12_-_56615679 1.564 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr9_-_98270321 1.561 NM_001083604
NM_001083605
PTCH1

patched 1

chrX_+_101967103 1.557 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr8_+_97505876 1.546 NM_002998
SDC2
syndecan 2
chr19_-_11373117 1.543 NM_020812
DOCK6
dedicator of cytokinesis 6
chr2_+_189156603 1.540 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr8_-_141467810 1.536 TRAPPC9
trafficking protein particle complex 9
chr12_+_57482922 1.525 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr11_-_2159925 1.513 IGF2
insulin-like growth factor 2 (somatomedin A)
chr20_+_34742656 1.512 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr7_+_73442426 1.507 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr2_+_8822112 1.498 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr2_-_164592512 1.484 NM_018086
FIGN
fidgetin
chr19_-_54692132 1.479 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr3_-_32023237 1.478 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr6_-_13486986 1.470 GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_68697997 1.468 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr9_-_16870664 1.465 BNC2
basonuclin 2
chr2_-_61697846 1.463 NM_014709
USP34
ubiquitin specific peptidase 34
chr3_+_8543539 1.462 LMCD1
LIM and cysteine-rich domains 1
chr1_+_204042191 1.462 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr5_+_36876899 1.448 NIPBL
Nipped-B homolog (Drosophila)
chr6_-_111136330 1.448 CDK19
cyclin-dependent kinase 19
chr16_+_29817426 1.446 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr1_+_164528914 1.443 PBX1
pre-B-cell leukemia homeobox 1
chr7_+_73442486 1.417 ELN
elastin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 2.50e-19 GO:0065007 biological regulation
1.16 1.28e-18 GO:0050794 regulation of cellular process
1.15 6.48e-18 GO:0050789 regulation of biological process
1.28 5.80e-15 GO:0048522 positive regulation of cellular process
1.27 6.93e-15 GO:0048518 positive regulation of biological process
1.08 4.56e-13 GO:0009987 cellular process
1.19 7.89e-11 GO:0023052 signaling
1.22 1.24e-10 GO:0048731 system development
1.20 8.86e-10 GO:0048856 anatomical structure development
1.23 4.04e-09 GO:0048519 negative regulation of biological process
1.19 6.40e-09 GO:0007275 multicellular organismal development
1.24 1.27e-08 GO:0048523 negative regulation of cellular process
1.17 1.81e-08 GO:0032502 developmental process
1.30 1.84e-08 GO:0007399 nervous system development
1.18 2.73e-08 GO:0031323 regulation of cellular metabolic process
1.28 3.72e-08 GO:0023051 regulation of signaling
1.18 5.30e-08 GO:0016043 cellular component organization
1.36 8.59e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.16 2.01e-07 GO:0019222 regulation of metabolic process
1.28 3.56e-07 GO:0009966 regulation of signal transduction
1.17 5.91e-07 GO:0007165 signal transduction
1.16 1.25e-06 GO:0080090 regulation of primary metabolic process
1.15 1.26e-06 GO:0051716 cellular response to stimulus
1.16 1.74e-06 GO:0071840 cellular component organization or biogenesis
1.23 2.38e-06 GO:0048583 regulation of response to stimulus
1.26 2.46e-06 GO:0009653 anatomical structure morphogenesis
1.34 2.91e-06 GO:0022008 neurogenesis
1.16 3.27e-06 GO:0060255 regulation of macromolecule metabolic process
1.34 1.41e-05 GO:0048699 generation of neurons
1.18 1.56e-05 GO:0071842 cellular component organization at cellular level
1.28 3.18e-05 GO:0031325 positive regulation of cellular metabolic process
1.27 3.62e-05 GO:0009893 positive regulation of metabolic process
1.28 5.29e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.28 9.38e-05 GO:0010646 regulation of cell communication
1.17 1.24e-04 GO:0031326 regulation of cellular biosynthetic process
1.21 1.25e-04 GO:0048513 organ development
1.17 1.34e-04 GO:0009889 regulation of biosynthetic process
1.18 1.66e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 2.18e-04 GO:0051128 regulation of cellular component organization
1.16 2.71e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.17 3.27e-04 GO:0010468 regulation of gene expression
1.16 3.55e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 3.62e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.27 5.32e-04 GO:0006793 phosphorus metabolic process
1.27 5.32e-04 GO:0006796 phosphate metabolic process
1.42 6.12e-04 GO:0007268 synaptic transmission
1.16 6.47e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.28 6.74e-04 GO:0032879 regulation of localization
1.35 7.06e-04 GO:0009725 response to hormone stimulus
1.34 7.15e-04 GO:0009719 response to endogenous stimulus
1.26 7.38e-04 GO:0010941 regulation of cell death
1.32 7.65e-04 GO:0007267 cell-cell signaling
1.39 9.35e-04 GO:0019226 transmission of nerve impulse
1.39 9.35e-04 GO:0035637 multicellular organismal signaling
1.09 1.10e-03 GO:0044237 cellular metabolic process
1.27 1.14e-03 GO:0007154 cell communication
1.45 1.21e-03 GO:0016568 chromatin modification
1.18 1.25e-03 GO:0065008 regulation of biological quality
1.30 1.31e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.19 1.34e-03 GO:0006464 protein modification process
1.37 1.96e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.30 2.09e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 2.09e-03 GO:0006325 chromatin organization
1.33 2.10e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 2.13e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.11 2.16e-03 GO:0044260 cellular macromolecule metabolic process
1.25 2.38e-03 GO:0043067 regulation of programmed cell death
1.35 2.47e-03 GO:0050878 regulation of body fluid levels
1.36 3.26e-03 GO:0010942 positive regulation of cell death
1.54 3.50e-03 GO:0003002 regionalization
1.16 3.50e-03 GO:0051252 regulation of RNA metabolic process
1.17 3.59e-03 GO:0048869 cellular developmental process
1.32 3.69e-03 GO:0010628 positive regulation of gene expression
1.17 3.83e-03 GO:0030154 cell differentiation
1.35 3.92e-03 GO:0051253 negative regulation of RNA metabolic process
1.37 4.35e-03 GO:0031175 neuron projection development
1.33 4.53e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.33 4.56e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 4.91e-03 GO:0043412 macromolecule modification
1.30 4.93e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.08 5.06e-03 GO:0044238 primary metabolic process
1.25 5.68e-03 GO:0042981 regulation of apoptosis
1.30 5.73e-03 GO:0006468 protein phosphorylation
1.25 6.23e-03 GO:0009892 negative regulation of metabolic process
1.25 6.82e-03 GO:0032268 regulation of cellular protein metabolic process
1.58 7.83e-03 GO:0048732 gland development
1.32 8.35e-03 GO:0010629 negative regulation of gene expression
1.34 8.59e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.31 8.80e-03 GO:0051254 positive regulation of RNA metabolic process
1.10 9.16e-03 GO:0043170 macromolecule metabolic process
1.32 9.43e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.30 9.56e-03 GO:0030182 neuron differentiation
1.16 1.13e-02 GO:0006355 regulation of transcription, DNA-dependent
1.23 1.15e-02 GO:0051246 regulation of protein metabolic process
1.26 1.31e-02 GO:0009891 positive regulation of biosynthetic process
1.31 1.47e-02 GO:0051276 chromosome organization
1.85 1.47e-02 GO:0030879 mammary gland development
1.51 1.57e-02 GO:0051129 negative regulation of cellular component organization
1.34 1.60e-02 GO:0043068 positive regulation of programmed cell death
1.26 1.77e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.12 1.93e-02 GO:0051179 localization
1.29 2.17e-02 GO:0009790 embryo development
1.18 2.24e-02 GO:0006996 organelle organization
1.25 2.44e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.25 2.49e-02 GO:0006351 transcription, DNA-dependent
1.14 2.69e-02 GO:0044267 cellular protein metabolic process
1.28 3.20e-02 GO:0009890 negative regulation of biosynthetic process
1.07 3.52e-02 GO:0008152 metabolic process
1.24 3.61e-02 GO:0031324 negative regulation of cellular metabolic process
1.13 3.62e-02 GO:0006810 transport
2.36 3.83e-02 GO:0060443 mammary gland morphogenesis
1.33 3.99e-02 GO:0043065 positive regulation of apoptosis
1.29 4.11e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 4.34e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.12 4.53e-02 GO:0051234 establishment of localization
1.30 4.66e-02 GO:0009887 organ morphogenesis
1.29 4.89e-02 GO:0030030 cell projection organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 8.76e-10 GO:0044424 intracellular part
1.06 2.79e-09 GO:0005622 intracellular
1.09 2.53e-08 GO:0005737 cytoplasm
1.46 2.05e-05 GO:0043005 neuron projection
1.28 2.72e-04 GO:0042995 cell projection
1.06 3.03e-04 GO:0043226 organelle
1.41 3.10e-04 GO:0045202 synapse
1.06 3.88e-04 GO:0043229 intracellular organelle
1.17 4.74e-04 GO:0005829 cytosol
1.25 4.80e-04 GO:0005794 Golgi apparatus
1.09 5.60e-04 GO:0044444 cytoplasmic part
1.06 8.97e-04 GO:0043227 membrane-bounded organelle
1.06 1.13e-03 GO:0043231 intracellular membrane-bounded organelle
1.27 1.55e-03 GO:0031410 cytoplasmic vesicle
1.27 2.08e-03 GO:0031982 vesicle
1.27 3.72e-03 GO:0031988 membrane-bounded vesicle
1.27 5.02e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.02 5.64e-03 GO:0005623 cell
1.02 6.67e-03 GO:0044464 cell part
1.29 1.00e-02 GO:0044431 Golgi apparatus part
1.19 1.07e-02 GO:0005654 nucleoplasm
1.52 1.13e-02 GO:0030424 axon
1.08 2.01e-02 GO:0044422 organelle part
1.39 2.07e-02 GO:0044456 synapse part
1.15 2.11e-02 GO:0031981 nuclear lumen
1.08 2.34e-02 GO:0044446 intracellular organelle part
1.35 2.35e-02 GO:0048471 perinuclear region of cytoplasm
1.13 3.07e-02 GO:0044459 plasma membrane part
1.40 3.24e-02 GO:0012506 vesicle membrane
1.11 4.37e-02 GO:0043234 protein complex
1.16 4.76e-02 GO:0012505 endomembrane system

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 9.04e-20 GO:0005515 protein binding
1.07 6.55e-14 GO:0005488 binding
1.32 7.00e-07 GO:0001071 nucleic acid binding transcription factor activity
1.32 7.00e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 1.84e-05 GO:0043565 sequence-specific DNA binding
1.33 3.96e-05 GO:0019899 enzyme binding
1.44 1.56e-04 GO:0003712 transcription cofactor activity
1.44 1.91e-04 GO:0000988 protein binding transcription factor activity
1.44 1.91e-04 GO:0000989 transcription factor binding transcription factor activity
1.40 3.27e-04 GO:0019904 protein domain specific binding
1.59 8.83e-04 GO:0003682 chromatin binding
1.24 2.24e-03 GO:0030528 transcription regulator activity
1.26 1.06e-02 GO:0042802 identical protein binding
1.23 1.62e-02 GO:0030234 enzyme regulator activity
1.28 2.52e-02 GO:0004672 protein kinase activity
1.29 3.07e-02 GO:0008092 cytoskeletal protein binding
2.07 4.20e-02 GO:0019888 protein phosphatase regulator activity
1.67 4.83e-02 GO:0005057 receptor signaling protein activity