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Motif ID: HIF1A.p2

Z-value: 1.860

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_7005764	7.819	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_65613211	7.163	NM_203464 NM_001005353	AK4	adenylate kinase 4
chr1_+_65613971	7.094		AK4	adenylate kinase 4
chr3_-_127541160	5.334	NM_007283	MGLL	monoglyceride lipase
chr3_-_127541975	5.267	NM_001003794	MGLL	monoglyceride lipase
chr8_+_17354562	5.033	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_-_74497406	4.963	NM_024599	RHBDF2	rhomboid 5 homolog 2 (Drosophila)
chr1_+_65613771	4.674	NM_013410	AK4	adenylate kinase 4
chr8_+_31497267	4.173	NM_013962	NRG1	neuregulin 1
chr3_-_145879222	4.145	NM_000935 NM_182943	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr7_+_55086922	3.948		EGFR	epidermal growth factor receptor
chr10_-_6019454	3.946	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chr11_+_18416111	3.808		LDHA	lactate dehydrogenase A
chr11_+_18416106	3.747		LDHA	lactate dehydrogenase A
chr11_+_18415917	3.399	NM_001135239 NM_001165415 NM_001165416 NM_005566	LDHA	lactate dehydrogenase A
chr13_-_44361032	3.356	NM_001242863 NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr3_-_145878936	3.250		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr5_-_131563481	3.149	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr7_-_77045706	3.093	NM_017439	PION	pigeon homolog (Drosophila)
chr12_+_107349673	2.662		C12orf23	chromosome 12 open reading frame 23
chr7_-_98741681	2.577	NM_001199847 NM_020429 NM_181349	SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr3_-_145878775	2.557		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr2_-_224903933	2.499	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_-_10588451	2.490	NM_002539	ODC1	ornithine decarboxylase 1
chr4_+_154605421	2.415	NM_003264	TLR2	toll-like receptor 2
chr4_+_154605441	2.388		TLR2	toll-like receptor 2
chr6_-_32805819	2.368		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chrX_-_13956530	2.323		GPM6B	glycoprotein M6B
chr1_+_193091283	2.322		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr19_+_14544216	2.214		PKN1	protein kinase N1
chr17_+_79651042	2.191		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr12_+_107349539	2.148	NM_152261	C12orf23	chromosome 12 open reading frame 23
chr5_-_150460550	2.118		TNIP1	TNFAIP3 interacting protein 1
chr3_+_23244486	2.069		UBE2E2	ubiquitin-conjugating enzyme E2E 2
chr10_-_133795447	2.045		BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3
chr10_+_91174438	2.039		IFIT5	interferon-induced protein with tetratricopeptide repeats 5
chr5_-_150460599	1.989	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr17_+_46985720	1.982	NM_023079	UBE2Z	ubiquitin-conjugating enzyme E2Z
chr10_-_79789290	1.974	NM_007055	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr11_+_65292526	1.959	NM_001048218 NM_020680	SCYL1	SCY1-like 1 (S. cerevisiae)
chr19_+_14544100	1.954	NM_002741	PKN1	protein kinase N1
chr7_+_156931609	1.937		UBE3C	ubiquitin protein ligase E3C
chr18_+_43913906	1.927		RNF165	ring finger protein 165
chr12_-_121734543	1.922	NM_172226	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr16_-_87903028	1.909	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr7_+_156931663	1.902		UBE3C	ubiquitin protein ligase E3C
chr10_-_133795311	1.880	NM_004052	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3
chr7_-_27170351	1.879	NM_002141	HOXA4	homeobox A4
chr5_+_17217474	1.875	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr6_+_71998514	1.864		OGFRL1	opioid growth factor receptor-like 1
chr5_+_149865310	1.843		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_-_36831156	1.839	NM_001130677	C17orf96	chromosome 17 open reading frame 96
chr15_+_67358194	1.837	NM_005902	SMAD3	SMAD family member 3
chr17_+_46985829	1.833		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr11_+_65292576	1.824		SCYL1	SCY1-like 1 (S. cerevisiae)
chr13_+_115079943	1.821	NM_001164144 NM_001164145 NM_032436	CHAMP1	chromosome alignment maintaining phosphoprotein 1
chr17_+_46985853	1.817		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr21_+_42797977	1.805	NM_002462 NM_001178046	MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr5_+_17217781	1.788		BASP1	brain abundant, membrane attached signal protein 1
chr7_+_128095881	1.773	NM_001098786 NM_013332	HILPDA	hypoxia inducible lipid droplet-associated
chr21_+_45719921	1.738	NM_002626	PFKL	phosphofructokinase, liver
chr1_+_227058241	1.730	NM_000447 NM_012486	PSEN2	presenilin 2 (Alzheimer disease 4)
chr6_+_34204928	1.728		HMGA1	high mobility group AT-hook 1
chr12_-_77459198	1.724	NM_203394	E2F7	E2F transcription factor 7
chr6_+_34204690	1.707		HMGA1	high mobility group AT-hook 1
chr9_+_35732498	1.701		CREB3	cAMP responsive element binding protein 3
chr1_-_212873104	1.698		BATF3	basic leucine zipper transcription factor, ATF-like 3
chr3_+_23244703	1.697	NM_152653	UBE2E2	ubiquitin-conjugating enzyme E2E 2
chr1_-_38218573	1.694		EPHA10	EPH receptor A10
chr21_+_45719964	1.682		PFKL	phosphofructokinase, liver
chr12_-_121734474	1.669		CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr15_+_67358161	1.659		SMAD3	SMAD family member 3
chr17_+_79651072	1.644		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr22_-_50964573	1.621	NM_001169110	SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)
chr19_-_5720136	1.619		LONP1	lon peptidase 1, mitochondrial
chrX_-_152939256	1.609		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr21_+_26934440	1.599		MIR155HG	MIR155 host gene (non-protein coding)
chr16_+_30709913	1.595
chr6_+_71998476	1.573	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr8_-_145515014	1.560		BOP1	block of proliferation 1
chr22_-_50964856	1.550	NM_001169109	SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)
chr6_-_32806009	1.521		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_+_193091165	1.518		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_233749749	1.510	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr10_+_111767877	1.498		ADD3	adducin 3 (gamma)
chr17_-_41622727	1.487		ETV4	ets variant 4
chr1_-_6662681	1.483		KLHL21	kelch-like 21 (Drosophila)
chr1_+_193091220	1.481		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr7_-_97601654	1.480
chr8_-_30515665	1.476	NM_002095	GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa
chr7_-_98741605	1.455		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr18_+_55102777	1.455	NM_004852	ONECUT2	one cut homeobox 2
chr1_-_8939150	1.450	NM_001428	ENO1	enolase 1, (alpha)
chr10_-_135171512	1.431	NM_001098483 NM_198472	C10orf125	chromosome 10 open reading frame 125
chr11_+_57435556	1.430		ZDHHC5	zinc finger, DHHC-type containing 5
chr19_-_5720155	1.426		LONP1	lon peptidase 1, mitochondrial
chrX_+_152599544	1.418	NM_001080485	ZNF275	zinc finger protein 275
chr5_-_121413967	1.408		LOX	lysyl oxidase
chr19_+_57154526	1.406	NM_001193628	LOC147670	uncharacterized LOC147670
chr19_-_16683188	1.400	NM_024881	SLC35E1	solute carrier family 35, member E1
chr7_+_156931631	1.394	NM_014671	UBE3C	ubiquitin protein ligase E3C
chr6_+_30539169	1.388	NM_001025091 NM_001090	ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1
chr3_-_150480917	1.387		SIAH2	seven in absentia homolog 2 (Drosophila)
chr7_-_22396511	1.382	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr12_+_7023490	1.373	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr19_+_984316	1.367	NM_024100	WDR18	WD repeat domain 18
chr1_-_111746917	1.361		DENND2D	DENN/MADD domain containing 2D
chr5_-_121413906	1.356		LOX	lysyl oxidase
chr19_-_5720158	1.356	NM_004793	LONP1	lon peptidase 1, mitochondrial
chr3_-_45267804	1.355	NM_015444	TMEM158	transmembrane protein 158 (gene/pseudogene)
chr18_-_71959109	1.351	NM_001190807 NM_001914 NM_148923	CYB5A	cytochrome b5 type A (microsomal)
chr2_-_233352530	1.350	NM_004826	ECEL1	endothelin converting enzyme-like 1
chr3_-_16555128	1.346	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr1_-_41328002	1.341	NM_133467	CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_-_148176392	1.341
chr6_+_71998508	1.340		OGFRL1	opioid growth factor receptor-like 1
chr7_-_108096693	1.332	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr6_-_101329197	1.331	NM_006828 NM_022091	ASCC3	activating signal cointegrator 1 complex subunit 3
chr1_+_193091196	1.330		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr3_-_52090090	1.321	NM_001947	DUSP7	dual specificity phosphatase 7
chr3_-_150480963	1.319	NM_005067	SIAH2	seven in absentia homolog 2 (Drosophila)
chr3_+_113666544	1.319	NM_173570	ZDHHC23	zinc finger, DHHC-type containing 23
chr9_-_136857285	1.312	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr2_-_10588273	1.311		ODC1	ornithine decarboxylase 1
chr16_-_75590107	1.302	NM_001077416 NM_001077418 NM_001077419	TMEM231	transmembrane protein 231
chr17_-_41623246	1.301	NM_001986	ETV4	ets variant 4
chr3_-_150480887	1.295		SIAH2	seven in absentia homolog 2 (Drosophila)
chr5_+_98104998	1.291	NM_001012761	RGMB	RGM domain family, member B
chr11_+_57435458	1.290	NM_015457	ZDHHC5	zinc finger, DHHC-type containing 5
chr6_-_101329006	1.284		ASCC3	activating signal cointegrator 1 complex subunit 3
chr15_-_83953465	1.266	NM_001717	BNC1	basonuclin 1
chr11_-_568419	1.258		MIR210HG	MIR210 host gene (non-protein coding)
chr8_-_125740650	1.246	NM_014751	MTSS1	metastasis suppressor 1
chr4_-_120548329	1.233	NM_033430	PDE5A	phosphodiesterase 5A, cGMP-specific
chr4_+_38869346	1.224	NM_138389	FAM114A1	family with sequence similarity 114, member A1
chr6_+_34205369	1.223		HMGA1	high mobility group AT-hook 1
chr4_+_146540522	1.222	NM_172250	MMAA	methylmalonic aciduria (cobalamin deficiency) cblA type
chr14_-_24740780	1.219		RABGGTA	Rab geranylgeranyltransferase, alpha subunit
chr17_+_45000483	1.208	NM_001012511 NM_004287 NM_054022	GOSR2	golgi SNAP receptor complex member 2
chr13_+_41363754	1.194		SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr5_+_127419407	1.191	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr15_+_98503907	1.191	NM_183376	ARRDC4	arrestin domain containing 4
chr15_+_98503938	1.179		ARRDC4	arrestin domain containing 4
chr7_-_102715171	1.177	NM_001111038	FBXL13	F-box and leucine-rich repeat protein 13
chr3_-_50374795	1.167		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr20_-_590909	1.163	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr2_-_113012601	1.158	NM_032494	ZC3H8	zinc finger CCCH-type containing 8
chr21_-_44495894	1.158	NM_000071	CBS	cystathionine-beta-synthase
chr11_+_57435311	1.142		ZDHHC5	zinc finger, DHHC-type containing 5
chr5_-_121414011	1.135	NM_002317	LOX	lysyl oxidase
chr16_+_31191430	1.135	NM_001170634 NM_001170937 NM_004960	FUS	fused in sarcoma
chr2_-_214016332	1.134	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr2_-_75062214	1.122
chr1_+_1243971	1.119	NM_153339	PUSL1	pseudouridylate synthase-like 1
chr2_+_65216526	1.115		SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr3_+_133292557	1.112		CDV3	CDV3 homolog (mouse)
chr17_+_45000493	1.112		GOSR2	golgi SNAP receptor complex member 2
chr1_+_166808721	1.103	NM_017542	POGK	pogo transposable element with KRAB domain
chr6_+_33589045	1.096	NM_002224	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3
chr19_+_50887592	1.096	NM_002691	POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr10_+_102747291	1.094	NM_001163812 NM_001163813 NM_001163814 NM_021830	C10orf2	chromosome 10 open reading frame 2
chrX_-_40506800	1.092	NM_144970	CXorf38	chromosome X open reading frame 38
chr14_-_53162418	1.091	NM_014584	ERO1L	ERO1-like (S. cerevisiae)
chr2_-_213403280	1.088	NM_001042599 NM_005235	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr1_+_117452359	1.087	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr11_+_65029312	1.083	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr20_-_3996035	1.080	NM_007219 NM_001134337 NM_001134338	RNF24	ring finger protein 24
chr10_+_101419169	1.078	NM_020354	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7
chr1_-_8938691	1.077		ENO1	enolase 1, (alpha)
chr11_+_33061560	1.075	NM_001145541	TCP11L1	t-complex 11 (mouse)-like 1
chr9_+_35732207	1.064	NM_006368	CREB3	cAMP responsive element binding protein 3
chr5_+_133861685	1.063	NM_015288	PHF15	PHD finger protein 15
chr2_+_173420873	1.054		PDK1	pyruvate dehydrogenase kinase, isozyme 1
chr6_+_34204663	1.053		HMGA1	high mobility group AT-hook 1
chr3_-_179169180	1.052		GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr10_+_60936346	1.043	NM_032439	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr3_-_16554992	1.041		RFTN1	raftlin, lipid raft linker 1
chr3_-_122746544	1.034		SEMA5B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr6_+_43738757	1.034		VEGFA	vascular endothelial growth factor A
chr21_+_43639202	1.034	NM_004915 NM_016818	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr11_+_33061291	1.033		TCP11L1	t-complex 11 (mouse)-like 1
chr19_+_38810540	1.026		KCNK6	potassium channel, subfamily K, member 6
chrX_-_152938742	1.007	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr1_-_159895279	1.003	NM_003564	TAGLN2	transgelin 2
chr12_-_106641675	0.994	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr11_+_576482	0.993	NM_020901	PHRF1	PHD and ring finger domains 1
chr6_-_31324564	0.989		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr5_+_156693051	0.984	NM_001037333 NM_001037332	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr3_+_25831548	0.973	NM_001145391 NM_017897	OXSM	3-oxoacyl-ACP synthase, mitochondrial
chr17_+_55162530	0.972	NM_003488	AKAP1	A kinase (PRKA) anchor protein 1
chr3_-_50329702	0.971	NM_006764	IFRD2	interferon-related developmental regulator 2
chr11_-_207403	0.970	NM_001098787 NM_016526	BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like
chr9_-_135545327	0.970		DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr1_+_184356364	0.968		C1orf21	chromosome 1 open reading frame 21
chr14_+_55034633	0.967		SAMD4A	sterile alpha motif domain containing 4A
chr3_-_156272909	0.966	NM_007107	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)
chr14_+_70078309	0.965	NM_014734	KIAA0247	KIAA0247
chr17_-_2614926	0.965	NM_015229	KIAA0664	KIAA0664
chr5_+_55033844	0.962	NM_001142549 NM_001166533 NM_024415	DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr11_-_59436488	0.962	NM_152716	PATL1	protein associated with topoisomerase II homolog 1 (yeast)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.29	3.75e-08	GO:0044260	cellular macromolecule metabolic process
1.22	1.07e-07	GO:0044237	cellular metabolic process
1.12	2.67e-07	GO:0009987	cellular process
1.33	3.21e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	4.78e-05	GO:0051234	establishment of localization
1.36	1.44e-04	GO:0048523	negative regulation of cellular process
1.28	2.00e-04	GO:0006807	nitrogen compound metabolic process
1.28	2.07e-04	GO:0034641	cellular nitrogen compound metabolic process
1.29	2.44e-04	GO:0006810	transport
1.57	3.44e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.26	3.55e-04	GO:0051179	localization
1.20	8.27e-04	GO:0043170	macromolecule metabolic process
1.46	8.57e-04	GO:0051641	cellular localization
1.50	1.03e-03	GO:0008104	protein localization
1.32	1.23e-03	GO:0048519	negative regulation of biological process
1.49	1.29e-03	GO:0051649	establishment of localization in cell
1.25	1.74e-03	GO:0060255	regulation of macromolecule metabolic process
1.54	2.44e-03	GO:0045184	establishment of protein localization
1.24	3.09e-03	GO:0031323	regulation of cellular metabolic process
1.42	3.76e-03	GO:0033036	macromolecule localization
1.16	3.78e-03	GO:0044238	primary metabolic process
1.22	4.26e-03	GO:0019222	regulation of metabolic process
1.23	4.37e-03	GO:0080090	regulation of primary metabolic process
1.14	6.15e-03	GO:0008152	metabolic process
1.28	6.49e-03	GO:0044267	cellular protein metabolic process
1.50	7.89e-03	GO:0031324	negative regulation of cellular metabolic process
1.48	9.04e-03	GO:0009892	negative regulation of metabolic process
1.35	1.03e-02	GO:0016070	RNA metabolic process
1.50	1.33e-02	GO:0015031	protein transport
1.14	1.50e-02	GO:0050794	regulation of cellular process
1.29	1.60e-02	GO:0090304	nucleic acid metabolic process
1.79	1.63e-02	GO:0044419	interspecies interaction between organisms
2.05	2.19e-02	GO:0071843	cellular component biogenesis at cellular level
1.30	3.41e-02	GO:0030154	cell differentiation
2.34	3.44e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.05	3.45e-02	GO:0022613	ribonucleoprotein complex biogenesis
1.44	3.54e-02	GO:0032268	regulation of cellular protein metabolic process
2.32	4.07e-02	GO:0022604	regulation of cell morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	8.64e-22	GO:0005622	intracellular
1.17	5.84e-21	GO:0044424	intracellular part
1.20	4.74e-14	GO:0043227	membrane-bounded organelle
1.20	4.92e-14	GO:0043231	intracellular membrane-bounded organelle
1.17	1.15e-13	GO:0043226	organelle
1.17	2.11e-13	GO:0043229	intracellular organelle
1.18	5.00e-10	GO:0005737	cytoplasm
1.25	7.23e-10	GO:0005634	nucleus
1.21	5.73e-08	GO:0044444	cytoplasmic part
1.41	3.71e-07	GO:0005829	cytosol
1.81	1.30e-05	GO:0005730	nucleolus
1.19	2.58e-05	GO:0044446	intracellular organelle part
1.19	4.65e-05	GO:0044422	organelle part
1.33	1.14e-04	GO:0044428	nuclear part
1.05	1.33e-04	GO:0044464	cell part
1.05	1.38e-04	GO:0005623	cell
1.35	4.79e-04	GO:0031981	nuclear lumen
2.20	6.85e-04	GO:0031252	cell leading edge
1.30	1.05e-03	GO:0070013	intracellular organelle lumen
1.28	1.91e-03	GO:0031974	membrane-enclosed lumen
1.29	1.93e-03	GO:0043233	organelle lumen
1.29	3.44e-03	GO:0031090	organelle membrane
1.34	3.75e-03	GO:0012505	endomembrane system
1.93	5.32e-03	GO:0005635	nuclear envelope
2.92	6.23e-03	GO:0031256	leading edge membrane
2.16	1.41e-02	GO:0031965	nuclear membrane
2.43	3.16e-02	GO:0001726	ruffle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	1.16e-11	GO:0005515	protein binding
1.10	5.51e-08	GO:0005488	binding
1.34	4.60e-05	GO:0000166	nucleotide binding
1.26	1.39e-04	GO:0003676	nucleic acid binding
1.49	4.98e-03	GO:0003723	RNA binding
1.44	5.46e-03	GO:0030528	transcription regulator activity
1.65	1.31e-02	GO:0019904	protein domain specific binding
1.29	1.50e-02	GO:0035639	purine ribonucleoside triphosphate binding
1.29	1.67e-02	GO:0032553	ribonucleotide binding
1.29	1.67e-02	GO:0032555	purine ribonucleotide binding
1.29	1.75e-02	GO:0017076	purine nucleotide binding