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• Activity deltas table
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Motif ID: HOXA9_MEIS1.p2

Z-value: 0.619

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_6215785	1.752	NM_001199640 NM_001199641 NM_033439	IL33	interleukin 33
chr12_-_9268513	1.236		A2M	alpha-2-macroglobulin
chr8_-_6420454	1.175	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr14_+_68168602	0.991	NM_152443	RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr2_+_237478379	0.848	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr8_-_17555158	0.740	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chrX_+_135278912	0.702	NM_001159701 NM_001159699	FHL1	four and a half LIM domains 1
chr1_+_33004771	0.677	NM_001040441	ZBTB8A	zinc finger and BTB domain containing 8A
chr1_-_622033	0.552	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr5_+_140800536	0.541	NM_018914 NM_032091 NM_032092	PCDHGA11	protocadherin gamma subfamily A, 11
chr2_+_169923531	0.540	NM_199204	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr12_-_9268522	0.538	NM_000014	A2M	alpha-2-macroglobulin
chr6_+_29274402	0.519	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr12_-_9268475	0.509		A2M	alpha-2-macroglobulin
chr7_+_115863004	0.477	NM_152829	TES	testis derived transcript (3 LIM domains)
chr12_-_9268440	0.474		A2M	alpha-2-macroglobulin
chr10_+_35484829	0.441	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr5_+_68800003	0.409	NM_001205255	OCLN	occludin
chr2_-_128439359	0.397	NM_001161404	LIMS2	LIM and senescent cell antigen-like domains 2
chr7_+_44646120	0.369	NM_001003941 NM_001165036 NM_002541	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chrX_-_105282714	0.359	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_+_180794268	0.355	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr21_-_35899046	0.352	NM_203418	RCAN1	regulator of calcineurin 1
chr8_-_117023	0.329	NM_001005504	OR4F21	olfactory receptor, family 4, subfamily F, member 21
chr19_+_10828725	0.326	NM_001005360 NM_001005361 NM_001005362 NM_001190716 NM_004945	DNM2	dynamin 2
chr11_-_105010460	0.316	NM_021571	CARD18	caspase recruitment domain family, member 18
chr19_+_10828763	0.307		DNM2	dynamin 2
chr19_+_10828813	0.304		DNM2	dynamin 2
chr1_+_367639	0.276	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr22_+_25591072	0.264		KIAA1671	KIAA1671
chr9_-_8733893	0.262	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr18_-_52969714	0.260	NM_001243236	TCF4	transcription factor 4
chr3_-_138478184	0.251	NM_006219	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide
chr19_+_10828772	0.250		DNM2	dynamin 2
chr17_-_41739261	0.241	NM_001040002	MEOX1	mesenchyme homeobox 1
chr3_+_151985828	0.241	NM_021038 NM_207292	MBNL1	muscleblind-like (Drosophila)
chr6_+_35200627	0.240		SCUBE3	signal peptide, CUB domain, EGF-like 3
chr3_-_71180061	0.239	NM_001244815	FOXP1	forkhead box P1
chr8_-_99129385	0.239	NM_005836	HRSP12	heat-responsive protein 12
chr18_-_47806361	0.238	NM_001204151	MBD1	methyl-CpG binding domain protein 1
chr1_-_169555624	0.237		F5	coagulation factor V (proaccelerin, labile factor)
chr5_+_140749830	0.235	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr17_-_3627073	0.220		ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr16_-_24942662	0.215		ARHGAP17	Rho GTPase activating protein 17
chr6_-_138539626	0.212	NM_021635	PBOV1	prostate and breast cancer overexpressed 1
chr2_+_102770401	0.207	NM_000877	IL1R1	interleukin 1 receptor, type I
chr1_+_115572414	0.205	NM_000549	TSHB	thyroid stimulating hormone, beta
chr14_-_94856926	0.199	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr10_+_63808968	0.195	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr3_-_52719514	0.188	NM_018313	PBRM1	polybromo 1
chr12_-_102591547	0.188	NM_002674	PMCH	pro-melanin-concentrating hormone
chrX_-_83757398	0.188	NM_001177478 NM_001177479 NM_144657	HDX	highly divergent homeobox
chr17_-_8424217	0.183		MYH10	myosin, heavy chain 10, non-muscle
chr7_+_73245192	0.181	NM_001305	CLDN4	claudin 4
chrX_-_129272014	0.172	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr3_-_71179715	0.168		FOXP1	forkhead box P1
chr6_-_29343063	0.167	NM_030959	OR12D3	olfactory receptor, family 12, subfamily D, member 3
chr7_-_143582363	0.166	NM_001206941	FAM115A	family with sequence similarity 115, member A
chrX_-_43832920	0.166	NM_000266	NDP	Norrie disease (pseudoglioma)
chr16_-_71748697	0.165	NM_015020	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
chr18_-_22930826	0.158
chr19_-_4559713	0.156	NM_032108	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr6_-_137540435	0.156		IFNGR1	interferon gamma receptor 1
chr17_-_38210888	0.153	NM_001079518 NM_014815	MED24	mediator complex subunit 24
chr3_+_82035288	0.150
chr15_+_97326629	0.149	NM_173499	SPATA8	spermatogenesis associated 8
chr4_+_123091757	0.147	NM_015312	KIAA1109	KIAA1109
chr1_-_155774769	0.144		GON4L	gon-4-like (C. elegans)
chr6_+_116850175	0.142	NM_153036	FAM26D	family with sequence similarity 26, member D
chr1_+_226012974	0.137	NM_000120	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr6_-_137540504	0.135		IFNGR1	interferon gamma receptor 1
chr18_+_9885722	0.131	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chr20_-_61002588	0.128	NM_080833	C20orf151	chromosome 20 open reading frame 151
chr17_+_39555993	0.128		GAST	gastrin
chr6_+_155538096	0.126	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr5_+_140602914	0.126	NM_018934	PCDHB14	protocadherin beta 14
chr17_+_16120465	0.124	NM_004278	PIGL	phosphatidylinositol glycan anchor biosynthesis, class L
chr1_-_169555710	0.124	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr15_+_100173182	0.121	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr4_-_83347778	0.117		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr18_-_60986968	0.116		BCL2	B-cell CLL/lymphoma 2
chr13_-_78493902	0.115	NM_001201397	EDNRB	endothelin receptor type B
chr1_+_152943127	0.115	NM_173080	SPRR4	small proline-rich protein 4
chr9_-_14086901	0.115		NFIB	nuclear factor I/B
chr7_+_104681378	0.113		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr10_-_75401492	0.112	NM_021245	MYOZ1	myozenin 1
chr1_-_13611532	0.108	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr7_+_80267782	0.106	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr20_-_45142192	0.105	NM_018102 NM_199441	ZNF334	zinc finger protein 334
chr8_+_123793988	0.105		ZHX2	zinc fingers and homeoboxes 2
chr7_+_80267972	0.105		CD36	CD36 molecule (thrombospondin receptor)
chr5_+_140753480	0.103	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr1_+_198608216	0.103		PTPRC	protein tyrosine phosphatase, receptor type, C
chr1_+_12976449	0.102	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr7_-_84751246	0.102	NM_152754	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr1_-_13390747	0.101	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr1_-_202130677	0.100	NM_001199797 NM_002832	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr12_-_51422012	0.099	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_-_4718948	0.096	NM_030774	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr8_+_123794043	0.093		ZHX2	zinc fingers and homeoboxes 2
chr4_+_95376396	0.091		PDLIM5	PDZ and LIM domain 5
chr16_+_4838397	0.091	NM_001253790 NM_001253791	LOC440335	uncharacterized LOC440335
chr4_-_152147520	0.091	NM_001009555 NM_001128923	SH3D19	SH3 domain containing 19
chr3_-_71179736	0.088		FOXP1	forkhead box P1
chr2_-_191878882	0.087		STAT1	signal transducer and activator of transcription 1, 91kDa
chr3_-_27498244	0.085	NM_003615	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr9_+_132897342	0.084		GPR107	G protein-coupled receptor 107
chr6_-_46889620	0.083	NM_001098518	GPR116	G protein-coupled receptor 116
chr9_-_73736513	0.082	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr16_+_88636810	0.082		ZC3H18	zinc finger CCCH-type containing 18
chr4_+_69313166	0.080	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr12_-_10562142	0.080	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 readthrough killer cell lectin-like receptor subfamily C, member 4
chr10_-_46619935	0.078	NM_001042357 NM_001042389	PTPN20B PTPN20A	protein tyrosine phosphatase, non-receptor type 20B protein tyrosine phosphatase, non-receptor type 20A
chr20_+_33759773	0.078	NM_006404	PROCR	protein C receptor, endothelial
chr12_-_71182699	0.078	NM_001207015	PTPRR	protein tyrosine phosphatase, receptor type, R
chr17_-_41738901	0.076	NM_004527 NM_013999	MEOX1	mesenchyme homeobox 1
chr7_+_143657019	0.074	NM_012369	OR2F1	olfactory receptor, family 2, subfamily F, member 1
chr14_-_73453651	0.073	NM_178441	ZFYVE1	zinc finger, FYVE domain containing 1
chr12_-_53045947	0.072	NM_000423	KRT2	keratin 2
chr13_-_70682458	0.071	NM_020866	KLHL1	kelch-like 1 (Drosophila)
chr2_+_115199898	0.070	NM_020868	DPP10	dipeptidyl-peptidase 10 (non-functional)
chrX_-_71792610	0.069		HDAC8	histone deacetylase 8
chr18_-_65182507	0.069		DSEL	dermatan sulfate epimerase-like
chr19_-_15235748	0.066		ILVBL	ilvB (bacterial acetolactate synthase)-like
chr12_-_120765555	0.066	NM_000928	PLA2G1B	phospholipase A2, group IB (pancreas)
chr1_-_21415672	0.065		EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr15_+_45028559	0.065	NM_080745 NM_182985	TRIM69	tripartite motif containing 69
chr11_+_57105819	0.064	NM_002559	P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3
chr4_+_119947816	0.063		SYNPO2	synaptopodin 2
chr5_-_160112266	0.063		ATP10B	ATPase, class V, type 10B
chr2_-_216259197	0.063		FN1	fibronectin 1
chr5_+_128300786	0.062		SLC27A6	solute carrier family 27 (fatty acid transporter), member 6
chr10_-_101945787	0.062	NM_001100626	ERLIN1	ER lipid raft associated 1
chr13_+_78109808	0.062	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr16_+_55515468	0.062	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr13_+_32313678	0.062	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr21_+_46117086	0.061	NM_198699	KRTAP10-12	keratin associated protein 10-12
chr4_+_39408472	0.060	NM_175737	KLB	klotho beta
chr21_-_32253843	0.059	NM_175858	KRTAP11-1	keratin associated protein 11-1
chr21_-_36252872	0.059		RUNX1	runt-related transcription factor 1
chr13_-_45048436	0.058	NM_001243798	TSC22D1	TSC22 domain family, member 1
chr3_-_69037498	0.057		C3orf64	chromosome 3 open reading frame 64
chr3_-_150966901	0.056	NM_001081455	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr2_-_165424993	0.056		GRB14	growth factor receptor-bound protein 14
chr3_-_10332408	0.056	NM_001134941 NM_016362	GHRL	ghrelin/obestatin prepropeptide
chr6_+_47749774	0.055	NM_181744	OPN5	opsin 5
chr7_+_142986680	0.054	NM_001224	CASP2	caspase 2, apoptosis-related cysteine peptidase
chr10_+_98740987	0.054	NM_015652	C10orf12	chromosome 10 open reading frame 12
chrX_-_71792897	0.054	NM_001166418 NM_001166419 NM_001166420 NM_001166422 NM_001166448 NM_018486	HDAC8	histone deacetylase 8
chr4_-_53617781	0.054	NM_001242690 NM_024534	ERVMER34-1	endogenous retrovirus group MER34, member 1
chr6_-_11111955	0.053	NM_207582	ERVFRD-1	endogenous retrovirus group FRD, member 1
chr17_-_46799879	0.052	NM_032391	PRAC	prostate cancer susceptibility candidate
chr6_+_18387580	0.052	NM_182757	RNF144B	ring finger protein 144B
chrX_-_24045302	0.051	NM_030624	KLHL15	kelch-like 15 (Drosophila)
chr14_-_106746056	0.051
chr6_-_131321868	0.050	NM_001252660	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr20_-_34243118	0.050		RBM12	RNA binding motif protein 12
chr1_-_23521221	0.050	NM_000864	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D
chr2_+_88824168	0.049	NM_152670	C2orf51	chromosome 2 open reading frame 51
chr3_-_56809594	0.049	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr11_+_120107348	0.048	NM_001244682	POU2F3	POU class 2 homeobox 3
chr4_+_2627158	0.048	NM_003704	FAM193A	family with sequence similarity 193, member A
chr22_+_38092994	0.045	NM_001039141	TRIOBP	TRIO and F-actin binding protein
chr17_-_56492938	0.045		RNF43	ring finger protein 43
chr1_-_19578030	0.044		KIAA0090	KIAA0090
chr3_+_158787040	0.043	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr11_+_68367824	0.043		PPP6R3	protein phosphatase 6, regulatory subunit 3
chr17_-_39191100	0.042	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr7_+_136553398	0.042	NM_001006627 NM_001006630	CHRM2	cholinergic receptor, muscarinic 2
chr20_-_62601140	0.042	NM_020713	ZNF512B	zinc finger protein 512B
chr3_-_52569021	0.042	NM_022908	NT5DC2	5'-nucleotidase domain containing 2
chr9_-_124922049	0.040	NM_014222	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr18_-_29340698	0.039	NM_001034172	MCART2	mitochondrial carrier triple repeat 2
chr6_+_73076431	0.039	NM_001168411	RIMS1	regulating synaptic membrane exocytosis 1
chr1_+_212475147	0.039	NM_001199756	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr6_-_27880173	0.038	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr12_+_50024326	0.038	NM_001031698	PRPF40B	PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr15_+_57511616	0.036	NM_207040	TCF12	transcription factor 12
chr9_+_130911731	0.036	NM_005564	LCN2	lipocalin 2
chr1_-_115238091	0.035	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr5_+_140261792	0.034	NM_018904 NM_031865	PCDHA13	protocadherin alpha 13
chr1_-_205391180	0.034	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr18_+_55816546	0.034	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr5_-_142815076	0.034	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_+_39989534	0.033	NM_016941 NM_203486	DLL3	delta-like 3 (Drosophila)
chr3_-_150996153	0.033	NM_014879	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr17_-_7590731	0.032	NM_000546 NM_001126112 NM_001126113 NM_001126114	TP53	tumor protein p53
chr17_+_7792034	0.032	NM_001005273 NM_005852	CHD3	chromodomain helicase DNA binding protein 3
chr4_-_120225599	0.031	NM_001170330	C4orf3	chromosome 4 open reading frame 3
chr6_-_117747017	0.031	NM_002944	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr6_-_42946887	0.031		PEX6	peroxisomal biogenesis factor 6
chr3_+_97158453	0.031	NM_173655	EPHA6	EPH receptor A6
chr3_-_194354009	0.031	NM_001011655 NM_001166305 NM_001166306 NM_138399	TMEM44	transmembrane protein 44
chr5_+_126984712	0.030	NM_001048252	CTXN3	cortexin 3
chr5_-_154230212	0.029	NM_032385	C5orf4	chromosome 5 open reading frame 4
chr10_-_23633771	0.029	NM_153714	C10orf67	chromosome 10 open reading frame 67
chrX_+_49354117	0.029	NM_001127212	GAGE1 GAGE2C GAGE2A	G antigen 1 G antigen 2C G antigen 2A
chr1_+_198608136	0.029	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr6_+_29141310	0.029	NM_030905	OR2J2	olfactory receptor, family 2, subfamily J, member 2
chr9_+_93589704	0.028	NM_001174167	SYK	spleen tyrosine kinase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.41	2.67e-02	GO:0032501	multicellular organismal process
20.96	2.92e-02	GO:0006957	complement activation, alternative pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.82	2.63e-02	GO:0045095	keratin filament

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.05	2.92e-03	GO:0002020	protease binding