Motif ID: KLF4.p3

Z-value: 1.471


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
KLF4chr9_-_1102507070.433.2e-02Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_45504686 5.919 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr6_+_37137882 5.755 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_-_220252569 4.800 DNPEP
aspartyl aminopeptidase
chr6_-_31550065 3.996 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr2_-_220252513 3.981 DNPEP
aspartyl aminopeptidase
chr2_-_220252627 3.646 NM_012100
DNPEP
aspartyl aminopeptidase
chr1_-_41328019 3.387 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr3_-_127541160 3.365 NM_007283
MGLL
monoglyceride lipase
chr1_-_41328002 3.352 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr5_-_131826426 3.312 NM_002198
IRF1
interferon regulatory factor 1
chr11_-_125933186 3.251 NM_001243597
NM_016952
CDON

Cdon homolog (mouse)

chr9_+_35732207 2.970 NM_006368
CREB3
cAMP responsive element binding protein 3
chr6_+_138188352 2.880 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_+_2039945 2.858 NM_004209
SYNGR3
synaptogyrin 3
chr5_-_16936290 2.808 MYO10
myosin X
chr19_-_47734215 2.658 NM_014417
BBC3
BCL2 binding component 3
chr9_-_38069082 2.539 SHB
Src homology 2 domain containing adaptor protein B
chr9_+_140500148 2.509 ARRDC1
arrestin domain containing 1
chr3_-_123603144 2.507 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr11_-_64645925 2.428 EHD1
EH-domain containing 1
chr9_+_35732498 2.425 CREB3
cAMP responsive element binding protein 3
chr8_-_37756971 2.406 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr9_+_140500097 2.283 ARRDC1
arrestin domain containing 1
chr10_+_104155431 2.264 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr17_-_74497406 2.250 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr6_+_4776641 2.224 NM_004824
CDYL
chromodomain protein, Y-like
chr3_-_127541975 2.186 NM_001003794
MGLL
monoglyceride lipase
chr17_+_77020229 2.172 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr8_-_80679897 2.137 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr17_+_77020278 2.084 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr5_+_10564431 2.057 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr5_+_118604504 2.038 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr6_+_44095357 1.972 NM_018426
TMEM63B
transmembrane protein 63B
chr10_-_105614952 1.959 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_+_35732629 1.958 CREB3
cAMP responsive element binding protein 3
chr10_-_49812996 1.943 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr17_-_72869068 1.902 NM_004110
NM_024417
FDXR

ferredoxin reductase

chr6_+_4776826 1.887 CDYL
chromodomain protein, Y-like
chr11_+_65292526 1.882 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr10_-_101380217 1.877 NM_031212
SLC25A28
solute carrier family 25, member 28
chr9_+_140500136 1.874 ARRDC1
arrestin domain containing 1
chr7_-_2354010 1.871 SNX8
sorting nexin 8
chr19_-_50432952 1.841 NM_016553
NUP62
nucleoporin 62kDa
chr10_-_101380160 1.836 SLC25A28
solute carrier family 25, member 28
chr9_+_140500054 1.815 NM_152285
ARRDC1
arrestin domain containing 1
chr10_-_135171512 1.810 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr16_+_50776012 1.808 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr5_-_32313069 1.797 NM_001040446
MTMR12
myotubularin related protein 12
chr1_-_212873306 1.792 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr6_-_44233244 1.787 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr18_+_57567191 1.769 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr15_+_75074714 1.769 CSK
c-src tyrosine kinase
chr4_-_2757750 1.761 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr14_+_21538339 1.743 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr11_-_65686439 1.729 NM_001135635
NM_031450
C11orf68

chromosome 11 open reading frame 68

chr8_+_145064167 1.709 NM_000837
NM_001009184
GRINA

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

chr10_-_104001229 1.706 NM_005029
PITX3
paired-like homeodomain 3
chr6_-_44233499 1.692 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_+_49866986 1.686 NM_001197302
NM_001197301
NM_014419
DKKL1


dickkopf-like 1


chr15_-_75743776 1.667 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr19_+_10381763 1.661 ICAM1
intercellular adhesion molecule 1
chr16_+_50775960 1.658 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr8_+_145064238 1.627 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr4_-_37687932 1.616 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr15_+_80445177 1.614 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr19_+_10196757 1.608 NM_018381
C19orf66
chromosome 19 open reading frame 66
chr11_+_65292576 1.590 SCYL1
SCY1-like 1 (S. cerevisiae)
chr16_+_11762235 1.575 NM_003498
SNN
stannin
chr1_-_173446273 1.564 LOC100506023
uncharacterized LOC100506023
chr10_+_111767877 1.561 ADD3
adducin 3 (gamma)
chr19_+_10197023 1.557 C19orf66
chromosome 19 open reading frame 66
chr19_+_6739697 1.539 NM_004240
TRIP10
thyroid hormone receptor interactor 10
chr1_-_38273852 1.533 NM_024640
YRDC
yrdC domain containing (E. coli)
chr6_-_29595746 1.528 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr20_-_3996035 1.498 NM_007219
NM_001134337
NM_001134338
RNF24


ring finger protein 24


chr10_+_111767685 1.490 NM_001121
NM_016824
ADD3

adducin 3 (gamma)

chr19_+_10196972 1.485 C19orf66
chromosome 19 open reading frame 66
chr6_-_32821412 1.478 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_32821743 1.475 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_37899227 1.470 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_-_2758018 1.457 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr1_+_155023810 1.444 ADAM15
ADAM metallopeptidase domain 15
chr9_-_123691442 1.441 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr16_+_30675777 1.437 NM_001105079
FBRS
fibrosin
chr6_-_32821592 1.422 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr16_-_402617 1.410 NM_003502
NM_181050
AXIN1

axin 1

chr1_+_955468 1.409 NM_198576
AGRN
agrin
chr10_+_13142055 1.406 NM_001008211
NM_001008212
NM_001008213
NM_021980
OPTN



optineurin



chr6_+_32821924 1.404 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr2_-_37898768 1.399 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr3_-_45267620 1.391 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr3_-_45267804 1.374 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr11_-_64646053 1.372 NM_006795
EHD1
EH-domain containing 1
chr20_+_35089817 1.371 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chrX_+_9432980 1.369 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr6_+_31588460 1.355 PRRC2A
proline-rich coiled-coil 2A
chr1_-_31712733 1.351 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr7_-_98741375 1.337 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr22_-_36784001 1.334 MYH9
myosin, heavy chain 9, non-muscle
chr5_-_32312943 1.331 MTMR12
myotubularin related protein 12
chr1_+_28585959 1.309 NM_031459
SESN2
sestrin 2
chr19_+_48828820 1.298 EMP3
epithelial membrane protein 3
chr22_-_36783851 1.293 MYH9
myosin, heavy chain 9, non-muscle
chr1_-_38273683 1.291 YRDC
yrdC domain containing (E. coli)
chr12_+_57610577 1.289 NM_007224
NXPH4
neurexophilin 4
chr17_+_46985853 1.280 UBE2Z
ubiquitin-conjugating enzyme E2Z
chr19_-_10679620 1.279 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr19_-_10444186 1.278 NM_133452
RAVER1
ribonucleoprotein, PTB-binding 1
chr10_-_101380086 1.270 SLC25A28
solute carrier family 25, member 28
chr20_-_56884488 1.265 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr10_-_3214963 1.264 PITRM1
pitrilysin metallopeptidase 1
chr11_-_72353435 1.264 NM_001143839
NM_001243784
PDE2A

phosphodiesterase 2A, cGMP-stimulated

chr6_+_149639054 1.264 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr14_-_24616429 1.259 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_-_5147739 1.258 NM_201400
NM_201598
FAM86A

family with sequence similarity 86, member A

chr16_-_49315682 1.257 NM_004352
CBLN1
cerebellin 1 precursor
chr18_-_77793914 1.247


chr7_+_73703704 1.246 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr11_-_128392061 1.244 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr1_-_38273823 1.237 YRDC
yrdC domain containing (E. coli)
chr1_+_2518464 1.237 FAM213B
family with sequence similarity 213, member B
chr2_+_162016926 1.236 NM_001199135
TANK
TRAF family member-associated NFKB activator
chr6_-_30654978 1.229 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr17_+_21188021 1.226 MAP2K3
mitogen-activated protein kinase kinase 3
chr10_-_3214979 1.226 NM_001242307
NM_001242309
NM_014889
PITRM1


pitrilysin metallopeptidase 1


chr6_+_14117857 1.223 NM_001040280
NM_004233
CD83

CD83 molecule

chr11_-_2950593 1.223 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr4_-_120548329 1.203 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr10_+_134000335 1.202 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr8_-_12612968 1.202 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr1_-_212873197 1.199 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr21_+_43639202 1.192 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr22_-_36783977 1.190 MYH9
myosin, heavy chain 9, non-muscle
chr11_-_65430427 1.186 NM_001145138
NM_001243984
NM_001243985
NM_021975
RELA



v-rel reticuloendotheliosis viral oncogene homolog A (avian)



chr19_+_50879681 1.186 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr1_+_100111430 1.182 NM_017734
PALMD
palmdelphin
chr17_-_31204071 1.178 MYO1D
myosin ID
chr1_-_38273846 1.173 YRDC
yrdC domain containing (E. coli)
chr6_+_31588523 1.160 PRRC2A
proline-rich coiled-coil 2A
chr6_+_160148608 1.146 NM_152857
WTAP
Wilms tumor 1 associated protein
chr6_+_31588444 1.143 NM_004638
NM_080686
PRRC2A

proline-rich coiled-coil 2A

chr5_-_176037091 1.141 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr20_+_388717 1.138 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr21_+_45719964 1.129 PFKL
phosphofructokinase, liver
chr6_+_31588524 1.128 PRRC2A
proline-rich coiled-coil 2A
chr19_+_14544216 1.125 PKN1
protein kinase N1
chr14_+_52118539 1.124 NM_152330
FRMD6
FERM domain containing 6
chr20_-_44539597 1.123 NM_001242921
PLTP
phospholipid transfer protein
chr21_+_45719921 1.121 NM_002626
PFKL
phosphofructokinase, liver
chr1_-_161102367 1.121 DEDD
death effector domain containing
chr11_+_65082288 1.121 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr19_+_47778099 1.119 NM_178511
PRR24
proline rich 24
chr11_+_2466171 1.116 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr17_-_41623246 1.115 NM_001986
ETV4
ets variant 4
chr7_-_2354050 1.113 NM_013321
SNX8
sorting nexin 8
chr8_+_145064583 1.109 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_3157696 1.108 NM_001069
TUBB2A
tubulin, beta 2A class IIa
chr19_+_49622480 1.098 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr19_-_1863546 1.096 NM_031918
KLF16
Kruppel-like factor 16
chr1_-_205782135 1.096 NM_173854
SLC41A1
solute carrier family 41, member 1
chr7_+_21468293 1.092


chr11_+_65686908 1.090 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr22_-_30722863 1.088 NM_001204240
NM_031937
TBC1D10A

TBC1 domain family, member 10A

chr17_-_1083008 1.086 NM_021962
ABR
active BCR-related gene
chr20_+_55966440 1.086 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr1_-_161102210 1.084 NM_001039712
DEDD
death effector domain containing
chr17_-_53499055 1.071 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr2_-_225907312 1.067 NM_014689
DOCK10
dedicator of cytokinesis 10
chr2_+_219433517 1.065 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr15_+_65134081 1.065 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr8_+_145149978 1.063 CYC1
cytochrome c-1
chr11_+_44587140 1.061 NM_001024844
NM_002231
CD82

CD82 molecule

chr9_-_38069207 1.057 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chrX_+_153775561 1.055 NM_001099857
NM_001145255
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chr10_+_82213892 1.054 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr1_-_33430285 1.050 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr19_+_47759802 1.045 CCDC9
coiled-coil domain containing 9
chr11_-_59436366 1.045 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr8_+_145149936 1.044 NM_001916
CYC1
cytochrome c-1
chr13_-_30169795 1.041 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_+_52311432 1.036 MAPK6
mitogen-activated protein kinase 6
chr16_-_4466595 1.034 CORO7
coronin 7
chr16_-_75529278 1.034


chr19_-_33166057 1.032 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr12_+_69004614 1.031 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr14_-_24615772 1.030 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_-_87417309 1.027 NM_024735
FBXO31
F-box protein 31
chr15_+_52311408 1.027 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr19_+_676346 1.022 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr1_-_1051458 1.020 C1orf159
chromosome 1 open reading frame 159
chr1_+_2487803 1.018 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr22_-_36784055 1.017 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr8_-_494834 1.016 C8orf42
chromosome 8 open reading frame 42
chr14_-_24615794 1.016 NM_002818
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr21_+_43639930 1.013 NM_207174
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_+_48828627 1.012 NM_001425
EMP3
epithelial membrane protein 3
chr1_-_153931077 1.010 CRTC2
CREB regulated transcription coactivator 2
chr17_+_21187967 1.008 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr16_-_4466607 1.008 CORO7
coronin 7
chr22_-_45636760 1.007 KIAA0930
KIAA0930

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 1.84e-24 GO:0009987 cellular process
1.14 1.50e-20 GO:0044237 cellular metabolic process
1.15 3.09e-14 GO:0044260 cellular macromolecule metabolic process
1.10 3.87e-14 GO:0008152 metabolic process
1.11 1.47e-12 GO:0044238 primary metabolic process
1.09 1.06e-11 GO:0065007 biological regulation
1.15 2.53e-11 GO:0031323 regulation of cellular metabolic process
1.12 2.91e-10 GO:0043170 macromolecule metabolic process
1.14 3.22e-10 GO:0019222 regulation of metabolic process
1.18 3.35e-10 GO:0071842 cellular component organization at cellular level
1.15 3.44e-10 GO:0016043 cellular component organization
1.09 3.49e-10 GO:0050794 regulation of cellular process
1.09 6.35e-10 GO:0050789 regulation of biological process
1.14 1.86e-09 GO:0080090 regulation of primary metabolic process
1.17 3.52e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.17 3.77e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 5.29e-09 GO:0071840 cellular component organization or biogenesis
1.14 1.43e-08 GO:0060255 regulation of macromolecule metabolic process
1.14 4.66e-08 GO:0034641 cellular nitrogen compound metabolic process
1.14 5.10e-08 GO:0006807 nitrogen compound metabolic process
1.21 5.16e-08 GO:0006996 organelle organization
1.31 5.31e-08 GO:0046907 intracellular transport
1.20 5.54e-08 GO:0006464 protein modification process
1.16 6.47e-08 GO:0010468 regulation of gene expression
1.15 1.26e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.29 1.47e-07 GO:0045184 establishment of protein localization
1.15 2.07e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 3.23e-07 GO:0015031 protein transport
1.17 3.63e-07 GO:0051252 regulation of RNA metabolic process
1.18 4.22e-07 GO:0043412 macromolecule modification
1.16 5.29e-07 GO:0044267 cellular protein metabolic process
1.17 5.86e-07 GO:0048869 cellular developmental process
1.20 8.17e-07 GO:0023051 regulation of signaling
1.12 1.19e-06 GO:0032502 developmental process
1.22 1.25e-06 GO:0051641 cellular localization
1.26 1.33e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.17 1.47e-06 GO:0030154 cell differentiation
1.16 1.49e-06 GO:0048522 positive regulation of cellular process
1.17 1.92e-06 GO:0048523 negative regulation of cellular process
1.24 3.42e-06 GO:0008104 protein localization
1.23 5.35e-06 GO:0051649 establishment of localization in cell
1.19 5.37e-06 GO:0034645 cellular macromolecule biosynthetic process
1.26 8.22e-06 GO:0048699 generation of neurons
1.15 8.68e-06 GO:0048519 negative regulation of biological process
1.14 8.82e-06 GO:0048518 positive regulation of biological process
1.21 1.24e-05 GO:0033036 macromolecule localization
1.16 1.46e-05 GO:0006355 regulation of transcription, DNA-dependent
1.25 1.50e-05 GO:0048468 cell development
1.13 1.88e-05 GO:0048856 anatomical structure development
1.18 1.91e-05 GO:0009059 macromolecule biosynthetic process
1.25 2.16e-05 GO:0022008 neurogenesis
1.20 2.39e-05 GO:0009966 regulation of signal transduction
1.14 3.23e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 4.88e-05 GO:0007399 nervous system development
1.13 5.29e-05 GO:0031326 regulation of cellular biosynthetic process
1.27 7.12e-05 GO:0030182 neuron differentiation
1.11 9.55e-05 GO:0051179 localization
1.24 1.20e-04 GO:0006351 transcription, DNA-dependent
1.27 1.34e-04 GO:0010628 positive regulation of gene expression
1.12 1.46e-04 GO:0051234 establishment of localization
1.18 2.24e-04 GO:0009653 anatomical structure morphogenesis
1.14 2.24e-04 GO:0044249 cellular biosynthetic process
1.27 3.35e-04 GO:0030030 cell projection organization
1.13 3.43e-04 GO:0009889 regulation of biosynthetic process
1.32 3.60e-04 GO:0044262 cellular carbohydrate metabolic process
1.12 4.23e-04 GO:0019538 protein metabolic process
1.14 5.08e-04 GO:0090304 nucleic acid metabolic process
1.13 5.27e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.15 6.04e-04 GO:0010467 gene expression
1.12 6.05e-04 GO:0006810 transport
1.34 6.42e-04 GO:0006886 intracellular protein transport
1.29 6.61e-04 GO:0070727 cellular macromolecule localization
1.30 8.40e-04 GO:0032990 cell part morphogenesis
1.29 9.00e-04 GO:0034613 cellular protein localization
1.30 9.09e-04 GO:0048858 cell projection morphogenesis
1.19 1.06e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.30 1.07e-03 GO:0031175 neuron projection development
1.36 1.23e-03 GO:0007411 axon guidance
1.25 1.43e-03 GO:0051254 positive regulation of RNA metabolic process
1.27 1.44e-03 GO:0000902 cell morphogenesis
1.31 1.45e-03 GO:0048812 neuron projection morphogenesis
1.22 1.48e-03 GO:0008219 cell death
1.26 1.55e-03 GO:0032989 cellular component morphogenesis
1.29 1.60e-03 GO:0043068 positive regulation of programmed cell death
1.19 1.64e-03 GO:0044248 cellular catabolic process
1.10 1.70e-03 GO:0007275 multicellular organismal development
1.21 1.74e-03 GO:0031324 negative regulation of cellular metabolic process
1.12 1.97e-03 GO:0009058 biosynthetic process
1.22 1.99e-03 GO:0016265 death
1.18 2.54e-03 GO:0009893 positive regulation of metabolic process
1.26 2.73e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 3.05e-03 GO:0051726 regulation of cell cycle
1.19 3.49e-03 GO:0043067 regulation of programmed cell death
1.28 3.50e-03 GO:0043065 positive regulation of apoptosis
1.28 3.54e-03 GO:0010942 positive regulation of cell death
1.20 4.01e-03 GO:0032774 RNA biosynthetic process
1.18 4.11e-03 GO:0031325 positive regulation of cellular metabolic process
1.19 4.12e-03 GO:0042981 regulation of apoptosis
1.22 4.23e-03 GO:0033554 cellular response to stress
1.19 4.26e-03 GO:0010941 regulation of cell death
1.11 4.30e-03 GO:0048731 system development
1.23 4.42e-03 GO:0012501 programmed cell death
1.20 5.19e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.26 5.37e-03 GO:0048666 neuron development
1.15 5.60e-03 GO:0016070 RNA metabolic process
1.23 8.10e-03 GO:0006915 apoptosis
1.27 8.53e-03 GO:0000904 cell morphogenesis involved in differentiation
1.22 9.38e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.24 1.13e-02 GO:0005975 carbohydrate metabolic process
1.22 1.21e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 1.31e-02 GO:0007409 axonogenesis
1.23 1.33e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.38 1.55e-02 GO:0007507 heart development
1.28 1.60e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.39 1.93e-02 GO:0005996 monosaccharide metabolic process
1.18 2.04e-02 GO:0009892 negative regulation of metabolic process
1.25 2.12e-02 GO:0051253 negative regulation of RNA metabolic process
1.18 2.57e-02 GO:0010646 regulation of cell communication
1.68 2.71e-02 GO:0006921 cellular component disassembly involved in apoptosis
1.15 3.33e-02 GO:0009056 catabolic process
1.15 3.36e-02 GO:0065009 regulation of molecular function
1.18 3.69e-02 GO:0007049 cell cycle
1.21 3.78e-02 GO:0016192 vesicle-mediated transport
1.24 3.99e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.19 4.04e-02 GO:0050793 regulation of developmental process
1.11 4.75e-02 GO:0042221 response to chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 4.36e-53 GO:0044424 intracellular part
1.11 2.40e-52 GO:0005622 intracellular
1.14 4.52e-41 GO:0005737 cytoplasm
1.12 2.46e-39 GO:0043226 organelle
1.12 1.18e-38 GO:0043229 intracellular organelle
1.13 3.26e-37 GO:0043227 membrane-bounded organelle
1.13 5.77e-37 GO:0043231 intracellular membrane-bounded organelle
1.16 1.97e-24 GO:0005634 nucleus
1.14 1.01e-22 GO:0044444 cytoplasmic part
1.14 5.74e-20 GO:0044446 intracellular organelle part
1.14 3.45e-19 GO:0044422 organelle part
1.23 5.23e-15 GO:0005829 cytosol
1.21 8.61e-13 GO:0044428 nuclear part
1.21 4.41e-10 GO:0031981 nuclear lumen
1.24 1.24e-09 GO:0005654 nucleoplasm
1.18 1.57e-09 GO:0031974 membrane-enclosed lumen
1.18 1.93e-09 GO:0070013 intracellular organelle lumen
1.17 1.44e-08 GO:0043233 organelle lumen
1.03 7.34e-08 GO:0044464 cell part
1.03 8.24e-08 GO:0005623 cell
1.25 3.33e-07 GO:0005794 Golgi apparatus
1.18 1.84e-06 GO:0012505 endomembrane system
1.27 8.73e-06 GO:0015630 microtubule cytoskeleton
1.12 1.23e-05 GO:0043234 protein complex
1.15 1.54e-05 GO:0031090 organelle membrane
1.12 6.53e-05 GO:0043228 non-membrane-bounded organelle
1.12 6.53e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.25 8.11e-05 GO:0044451 nucleoplasm part
1.10 3.33e-04 GO:0032991 macromolecular complex
1.44 9.35e-04 GO:0005819 spindle
1.15 1.19e-03 GO:0005856 cytoskeleton
1.18 1.34e-03 GO:0044430 cytoskeletal part
1.28 3.21e-03 GO:0043005 neuron projection
1.18 1.38e-02 GO:0042995 cell projection
1.30 1.73e-02 GO:0015629 actin cytoskeleton
1.15 3.53e-02 GO:0005783 endoplasmic reticulum
1.29 4.26e-02 GO:0005874 microtubule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 4.70e-46 GO:0005515 protein binding
1.08 5.95e-34 GO:0005488 binding
1.28 9.30e-07 GO:0019899 enzyme binding
1.15 5.58e-06 GO:0000166 nucleotide binding
1.11 3.59e-05 GO:0003676 nucleic acid binding
1.13 1.57e-04 GO:0003677 DNA binding
1.25 1.78e-04 GO:0043565 sequence-specific DNA binding
1.30 3.89e-04 GO:0019904 protein domain specific binding
1.14 5.62e-04 GO:0017076 purine nucleotide binding
1.14 6.09e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.14 6.78e-04 GO:0032553 ribonucleotide binding
1.14 6.78e-04 GO:0032555 purine ribonucleotide binding
1.31 1.20e-03 GO:0000988 protein binding transcription factor activity
1.31 1.20e-03 GO:0000989 transcription factor binding transcription factor activity
1.41 1.28e-03 GO:0003713 transcription coactivator activity
1.31 1.59e-03 GO:0003712 transcription cofactor activity
1.26 1.68e-03 GO:0008092 cytoskeletal protein binding
1.07 2.02e-03 GO:0003824 catalytic activity
1.19 2.51e-03 GO:0001071 nucleic acid binding transcription factor activity
1.19 2.51e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 7.92e-03 GO:0030554 adenyl nucleotide binding
1.14 1.18e-02 GO:0032559 adenyl ribonucleotide binding
1.14 1.37e-02 GO:0005524 ATP binding
1.13 2.28e-02 GO:0016740 transferase activity
1.21 2.32e-02 GO:0046983 protein dimerization activity
1.19 2.51e-02 GO:0016301 kinase activity
1.17 4.87e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups