Motif ID: LMO2.p2

Z-value: 1.106


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
LMO2chr11_-_33913835,
chr11_-_33891361,
chr11_-_33891485,
chr11_-_33891258,
chr11_-_33890931
-0.591.8e-03Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_7005764 7.248 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_-_39280377 5.138 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr15_+_89182038 3.764 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_89299980 3.553 HERC6
hect domain and RLD 6
chr4_+_89300110 2.870 HERC6
hect domain and RLD 6
chr17_-_39334439 2.512 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr11_-_441995 2.130 NM_001012302
ANO9
anoctamin 9
chrX_-_13956530 2.077 GPM6B
glycoprotein M6B
chr1_-_184943673 2.064 NM_052966
FAM129A
family with sequence similarity 129, member A
chr11_-_441956 2.031 ANO9
anoctamin 9
chr21_+_42797977 1.917 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr19_+_18284619 1.836 IFI30
interferon, gamma-inducible protein 30
chr19_+_18284631 1.827 IFI30
interferon, gamma-inducible protein 30
chr1_-_184943532 1.788 FAM129A
family with sequence similarity 129, member A
chr7_+_107204402 1.784 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_+_89299874 1.740 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr17_-_39306053 1.697 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr2_+_112812799 1.638 NM_032824
TMEM87B
transmembrane protein 87B
chr17_-_39296702 1.588 NM_030976
KRTAP4-6
keratin associated protein 4-6
chr19_+_57154526 1.536 NM_001193628
LOC147670
uncharacterized LOC147670
chr7_-_139762339 1.440 PARP12
poly (ADP-ribose) polymerase family, member 12
chr17_-_39254374 1.429 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr6_+_44095357 1.408 NM_018426
TMEM63B
transmembrane protein 63B
chr2_+_219745243 1.377 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_+_44788453 1.341 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr19_+_18284578 1.311 NM_006332
IFI30
interferon, gamma-inducible protein 30
chr1_+_90287404 1.291 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chr3_-_172428773 1.277 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr9_+_109625347 1.274 NM_021224
ZNF462
zinc finger protein 462
chr9_-_97401588 1.266 FBP1
fructose-1,6-bisphosphatase 1
chr16_+_1584161 1.254 NM_024600
TMEM204
transmembrane protein 204
chr11_-_72380107 1.238 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_+_183155393 1.198 LAMC2
laminin, gamma 2
chr1_+_203097427 1.188 ADORA1
adenosine A1 receptor
chr9_-_97401746 1.149 FBP1
fructose-1,6-bisphosphatase 1
chr8_+_104383701 1.128 CTHRC1
collagen triple helix repeat containing 1
chr2_+_65216526 1.101 SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr10_+_92980322 1.094 NM_032373
PCGF5
polycomb group ring finger 5
chr8_+_104383785 1.093 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr2_-_216878314 1.093 NM_018000
MREG
melanoregulin
chr1_+_90286469 1.088 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr6_-_3227776 1.077 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr1_+_3773844 1.062 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr9_-_97401833 1.058 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr1_-_3566563 1.055 NM_017818
WRAP73
WD repeat containing, antisense to TP73
chr10_-_118764559 1.049 KIAA1598
KIAA1598
chr1_+_90286595 1.038 LRRC8D
leucine rich repeat containing 8 family, member D
chr6_+_7541837 1.036 DSP
desmoplakin
chr11_+_63974144 1.023 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr7_-_994008 1.014 ADAP1
ArfGAP with dual PH domains 1
chr21_+_27011588 1.009 NM_021219
JAM2
junctional adhesion molecule 2
chr1_+_233749749 0.994 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr1_-_40367539 0.988 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr11_-_86666089 0.982 FZD4
frizzled family receptor 4
chr2_+_65216482 0.979 NM_003038
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr10_-_103347882 0.979 POLL
polymerase (DNA directed), lambda
chr17_+_77030471 0.966 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr22_-_37823503 0.962 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr4_-_41216455 0.955 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr13_+_50070096 0.921 PHF11
PHD finger protein 11
chr1_-_111746917 0.914 DENND2D
DENN/MADD domain containing 2D
chr10_+_12391708 0.896 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr2_-_231090443 0.891 NM_001185015
SP110
SP110 nuclear body protein
chr13_+_50069745 0.889 NM_001040443
PHF11
PHD finger protein 11
chr1_+_183155173 0.858 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr2_+_209271555 0.852 NM_005048
PTH2R
parathyroid hormone 2 receptor
chr17_-_39274587 0.849 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr18_-_43652153 0.849 NM_024430
PSTPIP2
proline-serine-threonine phosphatase interacting protein 2
chr20_+_61273823 0.848 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr7_-_131241321 0.846 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr15_+_41245635 0.842 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr17_-_39216343 0.841 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr4_+_154605441 0.836 TLR2
toll-like receptor 2
chr17_-_39316982 0.822 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr19_-_50432647 0.821 IL4I1
interleukin 4 induced 1
chr19_-_50432672 0.818 IL4I1
interleukin 4 induced 1
chr6_+_7541863 0.813 NM_001008844
NM_004415
DSP

desmoplakin

chr9_-_100881462 0.810 NM_014788
NM_033219
NM_033220
TRIM14


tripartite motif containing 14


chr20_+_61273786 0.802 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr11_+_19734821 0.798 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr3_-_122746544 0.797 SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr22_+_41697452 0.794 NM_017590
ZC3H7B
zinc finger CCCH-type containing 7B
chr7_-_77045706 0.793 NM_017439
PION
pigeon homolog (Drosophila)
chr12_+_56075329 0.792 NM_152637
METTL7B
methyltransferase like 7B
chr10_+_97889655 0.790 ZNF518A
zinc finger protein 518A
chr1_+_183155361 0.790 LAMC2
laminin, gamma 2
chr17_+_72772621 0.784 NM_017728
TMEM104
transmembrane protein 104
chr10_+_97889467 0.779 NM_014803
ZNF518A
zinc finger protein 518A
chr4_+_2420671 0.779 NM_001193282
LOC402160
uncharacterized LOC402160
chr12_-_63328663 0.778 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_+_39261640 0.777 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr5_-_172755195 0.775 STC2
stanniocalcin 2
chr4_+_8582216 0.773 NM_080819
GPR78
G protein-coupled receptor 78
chr16_-_75590107 0.766 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231


chr17_-_39324423 0.766 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr19_+_14544216 0.763 PKN1
protein kinase N1
chr12_+_124196941 0.762 ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr20_+_44486219 0.760 NM_080752
ZSWIM3
zinc finger, SWIM-type containing 3
chr5_-_172755418 0.756 STC2
stanniocalcin 2
chr17_-_45933138 0.744 NM_199262
SP6
Sp6 transcription factor
chr2_-_100758970 0.734 NM_002285
AFF3
AF4/FMR2 family, member 3
chr19_+_40697516 0.731 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr16_+_2039945 0.728 NM_004209
SYNGR3
synaptogyrin 3
chr2_-_224702200 0.724 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr21_-_37852387 0.715 NM_001146079
NM_144492
CLDN14

claudin 14

chr12_+_56075418 0.712 METTL7B
methyltransferase like 7B
chr19_-_39368889 0.711 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr14_+_105266878 0.704 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr20_+_48599511 0.702 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr3_+_31574119 0.701 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr21_+_43639202 0.697 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr12_+_90102639 0.696 LOC338758
uncharacterized LOC338758
chr1_-_144931967 0.695 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr20_+_58515408 0.690 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr1_-_153321021 0.685 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chr9_-_127905715 0.684 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr12_+_27485767 0.681 NM_001248002
NM_001248003
NM_001248004
NM_001248005
NM_020183
ARNTL2




aryl hydrocarbon receptor nuclear translocator-like 2




chr12_-_46662709 0.681 SLC38A1
solute carrier family 38, member 1
chr12_-_46662779 0.679 SLC38A1
solute carrier family 38, member 1
chr11_+_69467210 0.677 CCND1
cyclin D1
chr10_+_12391471 0.671 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr1_-_51796230 0.670 TTC39A
tetratricopeptide repeat domain 39A
chr22_-_50893728 0.666 SBF1
SET binding factor 1
chr3_+_140770412 0.663 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr19_-_633526 0.661 POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr19_+_38810461 0.660 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr5_-_95768660 0.660 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr4_-_40859081 0.659 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr6_+_143382030 0.659 AIG1
androgen-induced 1
chr19_-_47734215 0.654 NM_014417
BBC3
BCL2 binding component 3
chr1_+_26438267 0.648 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr12_-_46663207 0.642 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr19_+_38810751 0.637 KCNK6
potassium channel, subfamily K, member 6
chr4_+_3443691 0.634 NM_001528
HGFAC
HGF activator
chr6_+_138483024 0.632 NM_020340
KIAA1244
KIAA1244
chr7_-_107880492 0.624 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr9_-_130517552 0.624 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr19_+_13205956 0.624 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_39405938 0.624 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr2_+_223289212 0.623 SGPP2
sphingosine-1-phosphate phosphatase 2
chr3_-_184429609 0.623 NM_022149
MAGEF1
melanoma antigen family F, 1
chr1_+_169075869 0.618 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr22_-_50964573 0.610 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr19_+_38810540 0.608 KCNK6
potassium channel, subfamily K, member 6
chr2_-_105946104 0.604 NM_001142621
NM_004257
TGFBRAP1

transforming growth factor, beta receptor associated protein 1

chr6_+_143382045 0.602 AIG1
androgen-induced 1
chrX_-_152939256 0.602 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr7_-_994259 0.600 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr1_+_145438437 0.600 NM_006472
TXNIP
thioredoxin interacting protein
chr17_-_39211462 0.600 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr11_+_134201767 0.597 NM_138342
GLB1L2
galactosidase, beta 1-like 2
chr21_+_43933983 0.596 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_-_3773620 0.595 CEP104
centrosomal protein 104kDa
chr3_+_184056304 0.593 FAM131A
family with sequence similarity 131, member A
chr2_+_223289285 0.592 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr13_-_102068705 0.590 NM_052867
NALCN
sodium leak channel, non-selective
chr12_+_6833425 0.585 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr5_-_59189620 0.584 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_24605366 0.582 NM_006263
NM_176783
PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr4_+_3443659 0.579 HGFAC
HGF activator
chr1_+_205198058 0.578 NM_001242925
TMCC2
transmembrane and coiled-coil domain family 2
chr14_+_24605393 0.577 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_-_82461857 0.576 FAM46A
family with sequence similarity 46, member A
chr10_+_38645293 0.572 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr22_-_50970542 0.571 ODF3B
outer dense fiber of sperm tails 3B
chr8_-_134115309 0.566 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr4_-_21950373 0.566 NM_147182
KCNIP4
Kv channel interacting protein 4
chr10_-_116527955 0.565 ABLIM1
actin binding LIM protein 1
chr11_+_67810446 0.564 NM_006053
TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr2_-_224702300 0.564 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr7_-_2883649 0.564 NM_007353
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr2_+_47168312 0.562 NM_020458
TTC7A
tetratricopeptide repeat domain 7A
chr11_-_22647329 0.561 NM_022725
FANCF
Fanconi anemia, complementation group F
chr20_+_60877939 0.559 ADRM1
adhesion regulating molecule 1
chr7_+_766656 0.554 HEATR2
HEAT repeat containing 2
chr15_-_82554990 0.553 EFTUD1
elongation factor Tu GTP binding domain containing 1
chr12_+_108909049 0.543 NM_007076
FICD
FIC domain containing
chr2_-_160761192 0.541 LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chr4_-_80994309 0.539 NM_001145794
NM_058172
ANTXR2

anthrax toxin receptor 2

chr11_+_94277566 0.533 FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr22_+_41697583 0.529 ZC3H7B
zinc finger CCCH-type containing 7B
chr1_-_151804225 0.528 NM_005060
RORC
RAR-related orphan receptor C
chr2_-_55277459 0.524 RTN4
reticulon 4
chr1_+_162760491 0.521 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr1_-_1850704 0.521 NM_178545
TMEM52
transmembrane protein 52
chr5_-_58334936 0.520 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr19_+_17982753 0.516 NM_000453
SLC5A5
solute carrier family 5 (sodium iodide symporter), member 5
chr3_-_118753665 0.513 NM_001015887
IGSF11
immunoglobulin superfamily, member 11
chr1_+_167599329 0.508 NM_052862
RCSD1
RCSD domain containing 1
chr17_-_79876027 0.506 SIRT7
sirtuin 7
chr9_-_131940481 0.505 IER5L
immediate early response 5-like
chr9_-_131940538 0.503 NM_203434
IER5L
immediate early response 5-like
chr20_+_60878024 0.503 NM_007002
NM_175573
ADRM1

adhesion regulating molecule 1

chr17_-_39341126 0.503 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr22_-_37505602 0.503 TMPRSS6
transmembrane protease, serine 6
chr11_+_313852 0.503 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr2_+_48541767 0.498 NM_002158
FOXN2
forkhead box N2
chr1_+_89990442 0.498 LRRC8B
leucine rich repeat containing 8 family, member B
chr6_+_31539875 0.498 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_+_113376301 0.497 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 6.92e-03 GO:0023051 regulation of signaling
1.27 1.28e-02 GO:0007399 nervous system development
1.16 2.16e-02 GO:0007275 multicellular organismal development
1.15 2.76e-02 GO:0032502 developmental process
1.16 4.02e-02 GO:0048856 anatomical structure development
1.21 4.88e-02 GO:0030154 cell differentiation
1.32 4.93e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.37 1.11e-04 GO:0045095 keratin filament
2.93 1.52e-03 GO:0005581 collagen
1.06 6.03e-03 GO:0044424 intracellular part
1.05 1.80e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.09 1.32e-02 GO:0008060 ARF GTPase activator activity
1.56 1.86e-02 GO:0005083 small GTPase regulator activity
1.43 3.28e-02 GO:0030695 GTPase regulator activity
1.41 4.32e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.55 4.81e-02 GO:0032403 protein complex binding