Motif ID: MAZ.p2

Z-value: 1.880


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MAZchr16_+_298174260.554.2e-03Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_77155927 7.710 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr18_+_77155714 7.664 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr22_+_51113069 7.445 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr18_+_77155966 7.095 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_+_20081853 6.545 KAT2B
K(lysine) acetyltransferase 2B
chr18_+_77155943 6.265 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr4_-_16900256 6.203 LDB2
LIM domain binding 2
chr3_+_20081523 6.167 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr4_-_16900348 6.066 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr1_+_164528586 5.946 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr4_-_16900028 5.745 LDB2
LIM domain binding 2
chr12_+_123319977 5.511 NM_003959
HIP1R
huntingtin interacting protein 1 related
chr2_+_48757292 5.342 NM_001198595
NM_006873
STON1

stonin 1

chr20_+_42543417 4.966 NM_001098797
TOX2
TOX high mobility group box family member 2
chr9_+_139606916 4.938 NM_152421
FAM69B
family with sequence similarity 69, member B
chr19_-_291335 4.906 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr14_-_91526912 4.817 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr4_+_100871625 4.740 LOC256880
uncharacterized LOC256880
chr19_-_291168 4.659 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr17_+_81037504 4.603 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr17_-_47841517 4.565 NM_030802
FAM117A
family with sequence similarity 117, member A
chr3_+_110790460 4.456 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr1_+_210406194 4.308 NM_019605
SERTAD4
SERTA domain containing 4
chr5_+_139028483 4.062 CXXC5
CXXC finger protein 5
chr12_+_3068442 3.946 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr10_+_8096633 3.690 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr10_+_8096772 3.626 GATA3
GATA binding protein 3
chr6_+_15245702 3.611 JARID2
jumonji, AT rich interactive domain 2
chr19_-_3028901 3.585 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr13_-_72441312 3.577 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr5_+_139028025 3.406 NM_016463
CXXC5
CXXC finger protein 5
chr19_+_35760002 3.354 USF2
upstream transcription factor 2, c-fos interacting
chr3_+_58223228 3.340 NM_020676
ABHD6
abhydrolase domain containing 6
chr3_+_37903643 3.334 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chrX_+_66763868 3.331 NM_000044
AR
androgen receptor
chrX_-_119694871 3.329 CUL4B
cullin 4B
chr1_+_61547625 3.283 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr17_-_79008372 3.269 FLJ90757
uncharacterized LOC440465
chr3_+_58223415 3.268 ABHD6
abhydrolase domain containing 6
chr17_-_47841468 3.226 FAM117A
family with sequence similarity 117, member A
chr10_+_112631675 3.206 PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr4_+_6271588 3.182 WFS1
Wolfram syndrome 1 (wolframin)
chr1_+_87797371 3.181 LMO4
LIM domain only 4
chr2_-_43453146 3.170 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr7_-_143599163 3.162 NM_014719
NM_001206938
FAM115A

family with sequence similarity 115, member A

chr15_-_65067696 3.142 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr11_-_119234628 3.131 USP2
ubiquitin specific peptidase 2
chr2_+_24299751 3.130 LOC375190
UPF0638 protein B
chrX_+_9754465 3.124 NM_001649
SHROOM2
shroom family member 2
chr12_-_106532447 3.095 NUAK1
NUAK family, SNF1-like kinase, 1
chr4_+_41362750 3.087 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr14_-_21994342 3.074 SALL2
sal-like 2 (Drosophila)
chr1_+_212458867 3.068 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chrX_-_70473941 3.050 ZMYM3
zinc finger, MYM-type 3
chr3_-_15900928 3.021 NM_015199
ANKRD28
ankyrin repeat domain 28
chr3_+_12838170 2.979 NM_001162499
NM_012298
CAND2

cullin-associated and neddylation-dissociated 2 (putative)

chr7_+_30951414 2.952 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr12_+_57943806 2.912 KIF5A
kinesin family member 5A
chr1_-_53018630 2.900 ZCCHC11
zinc finger, CCHC domain containing 11
chr6_-_16761600 2.896 NM_000332
NM_001128164
ATXN1

ataxin 1

chr20_-_62680880 2.852 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr18_+_77160243 2.823 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr3_-_47620186 2.813 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr22_+_50585483 2.812 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr15_-_82338348 2.780 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr3_-_18466759 2.774 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr6_-_29527701 2.768 NM_006398
UBD
ubiquitin D
chr2_+_112656180 2.723 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chrX_-_54522318 2.723 NM_004463
FGD1
FYVE, RhoGEF and PH domain containing 1
chr15_-_82338459 2.719 MEX3B
mex-3 homolog B (C. elegans)
chrX_-_70473979 2.713 NM_201599
ZMYM3
zinc finger, MYM-type 3
chrX_-_119694719 2.696 NM_001079872
CUL4B
cullin 4B
chr3_+_32280154 2.689 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr18_+_11981421 2.672 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr9_+_139560193 2.669 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr9_+_139972195 2.667 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr6_-_79787784 2.637 PHIP
pleckstrin homology domain interacting protein
chr6_-_29527477 2.629 UBD
ubiquitin D
chr11_-_68518910 2.629 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr5_-_171881355 2.617 SH3PXD2B
SH3 and PX domains 2B
chr4_+_6271605 2.616 WFS1
Wolfram syndrome 1 (wolframin)
chr7_-_156685621 2.596 LMBR1
limb region 1 homolog (mouse)
chr7_+_30960914 2.595 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr9_+_115513050 2.592 NM_001012994
SNX30
sorting nexin family member 30
chr22_-_28197469 2.591 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr9_+_139560243 2.580 EGFL7
EGF-like-domain, multiple 7
chr12_+_9067130 2.576 NM_004426
PHC1
polyhomeotic homolog 1 (Drosophila)
chr7_+_94023872 2.567 NM_000089
COL1A2
collagen, type I, alpha 2
chr2_-_99347430 2.530 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr9_+_133971862 2.516 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr11_-_130184459 2.512 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr3_+_170075449 2.506 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr5_-_111093251 2.482 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr4_+_6271558 2.476 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr14_-_89883306 2.457 NM_005197
FOXN3
forkhead box N3
chr12_+_132379262 2.441 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr1_+_87794576 2.437 LMO4
LIM domain only 4
chr19_-_31840118 2.429 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr13_-_110438896 2.420 NM_003749
IRS2
insulin receptor substrate 2
chr6_+_117803779 2.415 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr18_-_72920989 2.391


chr12_+_3186520 2.373 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr4_-_149363498 2.335 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr10_+_76586299 2.330 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr3_+_8543508 2.330 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr2_-_165477818 2.318 GRB14
growth factor receptor-bound protein 14
chr14_+_56584854 2.313 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr2_-_165477986 2.303 GRB14
growth factor receptor-bound protein 14
chr11_+_59522905 2.292 STX3
syntaxin 3
chr1_-_20812727 2.289 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_2559396 2.285 NM_001040167
NM_001040168
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr14_+_56585147 2.279 PELI2
pellino homolog 2 (Drosophila)
chr9_+_130374466 2.278 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr2_+_235860616 2.276 NM_014521
SH3BP4
SH3-domain binding protein 4
chr10_-_75634219 2.268 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr10_-_35103894 2.254 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr19_+_1249882 2.246 MIDN
midnolin
chr1_+_110753313 2.246 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chrX_-_119694492 2.243 CUL4B
cullin 4B
chr9_+_139971938 2.236 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr12_-_118541655 2.233 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr4_+_1005609 2.206 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr14_-_30396811 2.197 NM_002742
PRKD1
protein kinase D1
chr2_+_203499819 2.197 NM_173511
FAM117B
family with sequence similarity 117, member B
chr4_+_1005395 2.184 FGFRL1
fibroblast growth factor receptor-like 1
chr10_-_81205091 2.180 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr6_-_84419018 2.179 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr11_-_33891361 2.173 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_74667553 2.168 NM_001015056
NM_033046
RTKN

rhotekin

chr10_-_126849066 2.158 NM_001329
CTBP2
C-terminal binding protein 2
chr4_-_102268626 2.156 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr11_-_2906960 2.151 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr1_+_65886315 2.139 NM_001003679
NM_001003680
NM_002303
NM_001198681
LEPR


LEPROT
leptin receptor


leptin receptor overlapping transcript
chr14_-_77494621 2.131 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr7_-_27153490 2.127 HOXA3
homeobox A3
chr1_+_15250578 2.126 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr2_+_159313466 2.123 NM_001005476
NM_003628
PKP4

plakophilin 4

chr2_-_43453737 2.117 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr9_+_133971902 2.106 AIF1L
allograft inflammatory factor 1-like
chr3_+_50192420 2.104 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr9_+_33817213 2.095 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr11_+_59522801 2.091 STX3
syntaxin 3
chr14_+_96505566 2.085 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr5_-_81046858 2.081 SSBP2
single-stranded DNA binding protein 2
chr8_+_144816287 2.076 LOC100128338
uncharacterized LOC100128338
chr19_-_19052032 2.075 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr1_+_93913566 2.048 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like


chr1_+_35258598 2.047 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr4_-_102267952 2.042 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_-_180076572 2.042 FLT4
fms-related tyrosine kinase 4
chr11_-_33891258 2.038 LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_102268333 2.028 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_-_156685875 2.020 NM_022458
LMBR1
limb region 1 homolog (mouse)
chr9_-_139581823 2.017 AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr6_-_84418705 2.015 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_-_57824787 2.013 R3HDM2
R3H domain containing 2
chr1_+_211432726 2.005 RCOR3
REST corepressor 3
chr3_+_39851028 2.004 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr6_-_31865439 1.999 EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr2_-_43453724 1.987 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr10_-_125853102 1.985 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr8_+_1711869 1.970 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr5_+_139027907 1.956 CXXC5
CXXC finger protein 5
chr18_+_46065367 1.935 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr6_-_29600859 1.931 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_3528058 1.929 NM_001409
MEGF6
multiple EGF-like-domains 6
chr5_+_139027955 1.929 CXXC5
CXXC finger protein 5
chr1_+_211432732 1.929 RCOR3
REST corepressor 3
chr4_+_74702272 1.926 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr12_+_53443834 1.914 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr4_-_110650965 1.914 NM_030821
PLA2G12A
phospholipase A2, group XIIA
chr17_-_48943672 1.914 NM_001243885
NM_005749
TOB1

transducer of ERBB2, 1

chr11_-_33890931 1.913 LMO2
LIM domain only 2 (rhombotin-like 1)
chr9_-_139581900 1.909 NM_001012727
NM_006412
AGPAT2

1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

chr8_-_22549901 1.909 NM_001199880
EGR3
early growth response 3
chr16_+_29817810 1.905 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr8_-_74659082 1.901 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr17_+_65821625 1.895 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr8_-_127570465 1.889 FAM84B
family with sequence similarity 84, member B
chr13_-_72440557 1.884 DACH1
dachshund homolog 1 (Drosophila)
chr3_-_169381417 1.883 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr5_+_176560882 1.878 NSD1
nuclear receptor binding SET domain protein 1
chr6_-_79787887 1.871 PHIP
pleckstrin homology domain interacting protein
chr6_-_144385647 1.869 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr8_-_22550708 1.865 NM_004430
EGR3
early growth response 3
chr5_-_114632240 1.863 NM_001040440
CCDC112
coiled-coil domain containing 112
chr1_-_184943673 1.856 NM_052966
FAM129A
family with sequence similarity 129, member A
chr2_+_238600878 1.852 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr10_-_126849556 1.849 NM_001083914
CTBP2
C-terminal binding protein 2
chr4_+_154387450 1.847 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr1_+_222791151 1.845 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr1_+_211432693 1.840 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr6_-_29600959 1.837 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr9_+_71320105 1.830 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr19_+_55996537 1.823 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr8_-_28243589 1.821 ZNF395
zinc finger protein 395
chr8_+_120220554 1.819 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_+_200323088 1.814


chr7_+_94024201 1.809 COL1A2
collagen, type I, alpha 2
chr9_+_127020242 1.803 NEK6
NIMA (never in mitosis gene a)-related kinase 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 1.07e-29 GO:0009987 cellular process
1.11 5.89e-19 GO:0050789 regulation of biological process
1.12 1.40e-18 GO:0050794 regulation of cellular process
1.16 3.55e-18 GO:0044260 cellular macromolecule metabolic process
1.13 8.50e-18 GO:0044237 cellular metabolic process
1.14 1.31e-16 GO:0043170 macromolecule metabolic process
1.10 2.12e-16 GO:0065007 biological regulation
1.11 6.96e-16 GO:0008152 metabolic process
1.12 3.80e-15 GO:0044238 primary metabolic process
1.20 1.83e-10 GO:0048523 negative regulation of cellular process
1.17 1.85e-10 GO:0048518 positive regulation of biological process
1.18 8.33e-10 GO:0048519 negative regulation of biological process
1.18 1.50e-09 GO:0044267 cellular protein metabolic process
1.17 5.66e-09 GO:0048522 positive regulation of cellular process
1.20 1.39e-08 GO:0006464 protein modification process
1.23 2.78e-08 GO:0009966 regulation of signal transduction
1.19 3.41e-08 GO:0043412 macromolecule modification
1.13 6.25e-08 GO:0031323 regulation of cellular metabolic process
1.14 1.37e-07 GO:0019538 protein metabolic process
1.19 1.43e-07 GO:0048583 regulation of response to stimulus
1.16 1.84e-07 GO:0044249 cellular biosynthetic process
1.20 2.03e-07 GO:0023051 regulation of signaling
1.16 2.41e-07 GO:0009058 biosynthetic process
1.12 6.90e-07 GO:0019222 regulation of metabolic process
1.13 1.04e-06 GO:0060255 regulation of macromolecule metabolic process
1.12 1.07e-06 GO:0023052 signaling
1.12 1.50e-06 GO:0080090 regulation of primary metabolic process
1.12 2.70e-06 GO:0007165 signal transduction
1.29 4.09e-06 GO:0009790 embryo development
1.24 7.89e-06 GO:0009892 negative regulation of metabolic process
1.11 1.11e-05 GO:0051716 cellular response to stimulus
1.12 1.83e-05 GO:0016043 cellular component organization
1.11 2.53e-05 GO:0032502 developmental process
1.25 2.65e-05 GO:0006351 transcription, DNA-dependent
1.24 2.79e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.11 3.18e-05 GO:0071840 cellular component organization or biogenesis
1.22 3.66e-05 GO:0010646 regulation of cell communication
1.17 4.24e-05 GO:0034645 cellular macromolecule biosynthetic process
1.23 5.76e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.24 6.44e-05 GO:0050793 regulation of developmental process
1.18 7.12e-05 GO:0009653 anatomical structure morphogenesis
1.17 7.75e-05 GO:0009059 macromolecule biosynthetic process
1.11 1.28e-04 GO:0007275 multicellular organismal development
1.28 1.99e-04 GO:0010629 negative regulation of gene expression
1.23 2.11e-04 GO:0031324 negative regulation of cellular metabolic process
1.17 2.81e-04 GO:0007399 nervous system development
1.18 3.57e-04 GO:0035556 intracellular signal transduction
1.27 4.65e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.10 6.15e-04 GO:0051179 localization
1.14 6.54e-04 GO:0090304 nucleic acid metabolic process
1.29 7.80e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.12 8.95e-04 GO:0010468 regulation of gene expression
1.12 9.20e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.14 9.26e-04 GO:0030154 cell differentiation
1.14 9.51e-04 GO:0048869 cellular developmental process
1.25 1.12e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.11 1.16e-03 GO:0048856 anatomical structure development
1.24 1.19e-03 GO:2000026 regulation of multicellular organismal development
1.13 1.20e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.25 1.41e-03 GO:0045595 regulation of cell differentiation
1.20 1.44e-03 GO:0032268 regulation of cellular protein metabolic process
1.11 1.45e-03 GO:0048731 system development
1.12 1.92e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.18 1.94e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.11 2.09e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 2.25e-03 GO:0016070 RNA metabolic process
1.25 2.28e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.27 2.44e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.12 2.72e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 3.05e-03 GO:0009890 negative regulation of biosynthetic process
1.24 3.16e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.19 3.81e-03 GO:0051246 regulation of protein metabolic process
1.17 3.84e-03 GO:0009893 positive regulation of metabolic process
1.18 4.07e-03 GO:0031325 positive regulation of cellular metabolic process
1.11 4.26e-03 GO:0031326 regulation of cellular biosynthetic process
1.25 4.30e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 4.82e-03 GO:0009889 regulation of biosynthetic process
1.10 4.88e-03 GO:0006807 nitrogen compound metabolic process
1.10 7.01e-03 GO:0034641 cellular nitrogen compound metabolic process
1.21 7.08e-03 GO:0031399 regulation of protein modification process
1.24 7.16e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.31 7.89e-03 GO:0009792 embryo development ending in birth or egg hatching
1.26 8.06e-03 GO:0051253 negative regulation of RNA metabolic process
1.15 8.46e-03 GO:0006996 organelle organization
1.19 9.30e-03 GO:0042127 regulation of cell proliferation
1.21 9.81e-03 GO:0051128 regulation of cellular component organization
1.30 1.43e-02 GO:0043009 chordate embryonic development
1.11 1.45e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.31 1.52e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.31 1.52e-02 GO:0016568 chromatin modification
1.11 1.54e-02 GO:0071842 cellular component organization at cellular level
1.29 1.59e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.10 1.79e-02 GO:0051234 establishment of localization
1.28 1.85e-02 GO:0040008 regulation of growth
1.12 2.31e-02 GO:0051252 regulation of RNA metabolic process
1.13 2.46e-02 GO:0010467 gene expression
1.25 2.52e-02 GO:0009967 positive regulation of signal transduction
1.10 3.93e-02 GO:0006810 transport
1.15 4.46e-02 GO:0033036 macromolecule localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.29e-37 GO:0005622 intracellular
1.09 2.09e-35 GO:0044424 intracellular part
1.12 1.04e-28 GO:0005737 cytoplasm
1.10 4.79e-23 GO:0043227 membrane-bounded organelle
1.10 7.41e-23 GO:0043231 intracellular membrane-bounded organelle
1.09 3.98e-22 GO:0043226 organelle
1.09 4.72e-22 GO:0043229 intracellular organelle
1.12 1.37e-17 GO:0044444 cytoplasmic part
1.03 1.05e-11 GO:0005623 cell
1.03 1.31e-11 GO:0044464 cell part
1.20 2.89e-11 GO:0005829 cytosol
1.11 3.44e-11 GO:0005634 nucleus
1.17 6.27e-09 GO:0070013 intracellular organelle lumen
1.17 9.85e-09 GO:0043233 organelle lumen
1.19 2.69e-08 GO:0031981 nuclear lumen
1.16 2.79e-08 GO:0031974 membrane-enclosed lumen
1.22 4.62e-08 GO:0005654 nucleoplasm
1.09 9.55e-08 GO:0044446 intracellular organelle part
1.09 1.05e-07 GO:0044422 organelle part
1.27 3.33e-06 GO:0044451 nucleoplasm part
1.15 4.30e-06 GO:0044428 nuclear part
1.71 5.07e-06 GO:0005925 focal adhesion
1.44 1.98e-05 GO:0016323 basolateral plasma membrane
1.17 2.53e-05 GO:0012505 endomembrane system
1.55 2.96e-05 GO:0005912 adherens junction
1.51 3.66e-05 GO:0070161 anchoring junction
1.65 3.78e-05 GO:0005924 cell-substrate adherens junction
1.63 4.47e-05 GO:0030055 cell-substrate junction
1.43 9.02e-05 GO:0016604 nuclear body
1.11 1.64e-04 GO:0043234 protein complex
1.19 3.54e-04 GO:0005783 endoplasmic reticulum
1.24 1.17e-03 GO:0044431 Golgi apparatus part
1.27 1.25e-03 GO:0000139 Golgi membrane
1.34 1.60e-03 GO:0015629 actin cytoskeleton
1.12 1.85e-03 GO:0031090 organelle membrane
1.16 1.75e-02 GO:0005794 Golgi apparatus
1.18 2.55e-02 GO:0031982 vesicle
1.18 2.86e-02 GO:0031410 cytoplasmic vesicle
1.08 4.56e-02 GO:0032991 macromolecular complex
1.51 4.58e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 1.81e-35 GO:0005515 protein binding
1.07 5.83e-26 GO:0005488 binding
1.27 2.37e-06 GO:0019899 enzyme binding
1.10 2.32e-05 GO:0043167 ion binding
1.10 2.76e-05 GO:0046872 metal ion binding
1.10 2.99e-05 GO:0043169 cation binding
1.25 3.94e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.13 1.02e-04 GO:0000166 nucleotide binding
1.23 1.53e-04 GO:0016301 kinase activity
1.07 1.11e-03 GO:0003824 catalytic activity
1.19 1.91e-03 GO:0001071 nucleic acid binding transcription factor activity
1.19 1.91e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.24 2.59e-03 GO:0004672 protein kinase activity
1.21 3.29e-03 GO:0042802 identical protein binding
1.19 3.59e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.13 5.29e-03 GO:0016740 transferase activity
1.18 5.39e-03 GO:0030528 transcription regulator activity
1.27 5.42e-03 GO:0019904 protein domain specific binding
1.12 1.04e-02 GO:0017076 purine nucleotide binding
1.40 1.05e-02 GO:0003682 chromatin binding
1.12 1.22e-02 GO:0032553 ribonucleotide binding
1.12 1.22e-02 GO:0032555 purine ribonucleotide binding
1.13 1.72e-02 GO:0030554 adenyl nucleotide binding
1.12 1.73e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.30 1.95e-02 GO:0016563 transcription activator activity
1.25 2.25e-02 GO:0004674 protein serine/threonine kinase activity
1.13 2.50e-02 GO:0032559 adenyl ribonucleotide binding
1.17 2.95e-02 GO:0030234 enzyme regulator activity
1.29 4.40e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds