Motif ID: MYBL2.p2

Z-value: 0.782


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MYBL2chr20_+_42295708-0.281.7e-01Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_32430370 1.688 NM_004011
NM_004012
DMD

dystrophin

chr2_-_198540583 1.630 NM_144629
RFTN2
raftlin family member 2
chrX_-_125686792 1.365 NM_178470
DCAF12L1
DDB1 and CUL4 associated factor 12-like 1
chr1_+_84630014 1.343 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr9_-_74675498 1.289 NM_001128618
C9orf57
chromosome 9 open reading frame 57
chr9_-_14086901 1.240 NFIB
nuclear factor I/B
chrX_-_33229428 1.097 NM_004006
DMD
dystrophin
chr9_+_79056581 1.021 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr10_+_94833646 1.008 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr3_-_15839674 0.972 NM_001195098
ANKRD28
ankyrin repeat domain 28
chrX_-_70475046 0.945 NM_001171162
ZMYM3
zinc finger, MYM-type 3
chr3_-_137851123 0.868 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr10_+_94833231 0.832 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chrX_+_118108575 0.804 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr11_-_71791734 0.794 NUMA1
nuclear mitotic apparatus protein 1
chr17_+_47866061 0.784 KAT7
K(lysine) acetyltransferase 7
chrX_+_118108595 0.769 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr17_+_47865980 0.749 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
KAT7




K(lysine) acetyltransferase 7




chr5_-_39425030 0.738 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_57511616 0.730 NM_207040
TCF12
transcription factor 12
chr17_+_47866119 0.701 KAT7
K(lysine) acetyltransferase 7
chr13_-_48987247 0.692 LPAR6
lysophosphatidic acid receptor 6
chr5_-_39424930 0.691 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_95274520 0.691 GEM
GTP binding protein overexpressed in skeletal muscle
chr1_+_84767288 0.690 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr3_-_48672807 0.654 SLC26A6
solute carrier family 26, member 6
chr1_+_210406194 0.654 NM_019605
SERTAD4
SERTA domain containing 4
chr5_-_39425297 0.653 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chrX_-_128788913 0.618 NM_017413
APLN
apelin
chr5_+_73109342 0.617 NM_001244364
RGNEF
190 kDa guanine nucleotide exchange factor
chr1_+_84630374 0.600 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_33701678 0.600 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_190627923 0.598 NM_022353
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr13_+_97999289 0.591


chr17_-_1248346 0.559 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr17_-_67138013 0.556 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr13_-_48987017 0.543 LPAR6
lysophosphatidic acid receptor 6
chr15_-_77154284 0.541 NM_001145923
SCAPER
S-phase cyclin A-associated protein in the ER
chr8_-_95274540 0.540 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr3_-_56698073 0.537 NM_015224
FAM208A
family with sequence similarity 208, member A
chr9_+_120466607 0.535 TLR4
toll-like receptor 4
chr6_+_153019029 0.510 NM_025107
MYCT1
myc target 1
chr1_+_100326765 0.509 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr9_-_124984018 0.499 NM_001242335
LHX6
LIM homeobox 6
chr11_-_71791434 0.487 NM_006185
NUMA1
nuclear mitotic apparatus protein 1
chr18_+_72922725 0.482 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr3_+_45927995 0.473 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr9_-_125941304 0.454 STRBP
spermatid perinuclear RNA binding protein
chr3_-_197300193 0.450 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chrX_-_70474402 0.450 NM_001171163
NM_005096
ZMYM3

zinc finger, MYM-type 3

chr9_+_120466625 0.446 TLR4
toll-like receptor 4
chr3_-_48672925 0.443 NM_022911
NM_134263
NM_134426
SLC26A6


solute carrier family 26, member 6


chr18_-_19748928 0.436 LOC100128893
uncharacterized LOC100128893
chr15_-_55652777 0.435 CCPG1
cell cycle progression 1
chr1_+_15272414 0.430 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr5_-_88119604 0.420 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr9_+_120466453 0.416 NM_138554
TLR4
toll-like receptor 4
chr9_-_14398981 0.416 NM_001190738
NFIB
nuclear factor I/B
chr2_-_165424993 0.410 GRB14
growth factor receptor-bound protein 14
chr1_+_212475147 0.394 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr19_-_17414083 0.386 NM_024527
ABHD8
abhydrolase domain containing 8
chr8_-_93111915 0.379 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_112824526 0.379 NM_001085377
MCC
mutated in colorectal cancers
chr3_-_187452669 0.379 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr12_+_56915587 0.371 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chrX_+_149613719 0.370 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr1_-_211751953 0.365 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_126327397 0.359 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chrX_-_115594136 0.350 NM_001017978
CXorf61
chromosome X open reading frame 61
chr12_-_42877743 0.345 PRICKLE1
prickle homolog 1 (Drosophila)
chr11_-_107436423 0.344 NM_138775
ALKBH8
alkB, alkylation repair homolog 8 (E. coli)
chr7_+_150382783 0.343 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr6_+_148663953 0.341 SASH1
SAM and SH3 domain containing 1
chr12_-_71031174 0.338 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_+_33701320 0.332 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_-_48987652 0.330 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chrX_-_77914824 0.326 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr1_+_92414927 0.325 NM_001242805
NM_001242806
NM_001242807
NM_001242808
NM_001242810
NM_207189
BRDT





bromodomain, testis-specific





chrX_-_10588458 0.323 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr4_+_41540187 0.321 LIMCH1
LIM and calponin homology domains 1
chr4_+_148402244 0.318 EDNRA
endothelin receptor type A
chr10_+_35464514 0.314 NM_182769
NM_182770
CREM

cAMP responsive element modulator

chr11_+_33563772 0.312 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr17_-_16097882 0.311 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr3_-_12941547 0.310 IQSEC1
IQ motif and Sec7 domain 1
chrX_-_19988381 0.309 NM_198279
CXorf23
chromosome X open reading frame 23
chr1_+_84630575 0.308 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr19_+_41869848 0.306 NM_001098825
TMEM91
transmembrane protein 91
chr3_+_113616317 0.306 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr1_+_221053000 0.302 HLX
H2.0-like homeobox
chr10_-_99052358 0.297 ARHGAP19
Rho GTPase activating protein 19
chr6_+_151561094 0.296 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_114478117 0.293 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr2_+_33738941 0.293 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_124805896 0.293 HEPACAM
hepatic and glial cell adhesion molecule
chr9_-_5968367 0.289


chr6_+_148663728 0.287 NM_015278
SASH1
SAM and SH3 domain containing 1
chr2_-_70475563 0.287 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr16_-_71610948 0.287 NM_000353
TAT
tyrosine aminotransferase
chr19_-_13947101 0.283 LOC284454
uncharacterized LOC284454
chr14_-_20774089 0.283 TTC5
tetratricopeptide repeat domain 5
chr1_-_197552304 0.280 DENND1B
DENN/MADD domain containing 1B
chr2_+_138721807 0.280 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_143886898 0.279 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr9_-_131709783 0.279 NM_014908
DOLK
dolichol kinase
chr6_-_55740387 0.277 BMP5
bone morphogenetic protein 5
chr6_-_55740358 0.276 NM_021073
BMP5
bone morphogenetic protein 5
chr5_+_61874561 0.275 NM_181506
LRRC70
leucine rich repeat containing 70
chr2_+_143886969 0.274 ARHGAP15
Rho GTPase activating protein 15
chrX_-_135962872 0.271 RBMX
RNA binding motif protein, X-linked
chr19_-_58485901 0.270 NM_152474
C19orf18
chromosome 19 open reading frame 18
chr11_+_100862719 0.270 NM_032021
TMEM133
transmembrane protein 133
chr12_+_107168336 0.266 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr14_+_24867926 0.263 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr9_-_95298251 0.261 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr12_-_42877785 0.259 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr21_+_30517897 0.256 C21orf7
chromosome 21 open reading frame 7
chr15_-_77176191 0.256 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr1_+_167064086 0.255 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr6_+_27292539 0.254 NM_032030
FKSG83
FKSG83
chr9_+_72658496 0.250 NM_153267
MAMDC2
MAM domain containing 2
chr4_-_186732047 0.249 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr1_+_174844655 0.241 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_9129583 0.240 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_+_210444364 0.240 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr8_-_28243941 0.238 NM_018660
ZNF395
zinc finger protein 395
chr5_+_161274939 0.236 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_3371723 0.235 NM_198227
RGS12
regulator of G-protein signaling 12
chr12_-_62997207 0.229 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr19_-_19144304 0.227 SUGP2
SURP and G patch domain containing 2
chr12_+_20963637 0.227 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr17_-_48227873 0.227 NM_032595
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr15_-_93277303 0.226 FAM174B
family with sequence similarity 174, member B
chr16_+_29674564 0.226 SPN
sialophorin
chr9_+_4792974 0.222 RCL1
RNA terminal phosphate cyclase-like 1
chr19_-_19144262 0.222 SUGP2
SURP and G patch domain containing 2
chr12_-_42877413 0.221 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_-_152590983 0.219 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr22_+_40573879 0.214 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr2_+_33661392 0.213 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_186877413 0.212 SORBS2
sorbin and SH3 domain containing 2
chr6_-_111888520 0.209 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr4_-_166033924 0.209 TMEM192
transmembrane protein 192
chrX_+_105066531 0.209 NM_198465
NRK
Nik related kinase
chr1_+_163038395 0.204 NM_001102445
RGS4
regulator of G-protein signaling 4
chr16_+_524843 0.203 NM_001142272
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr1_-_9129666 0.201 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr12_-_76478410 0.201 NAP1L1
nucleosome assembly protein 1-like 1
chr3_+_185046682 0.200 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr7_+_138144847 0.200 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr12_+_20724797 0.198 NM_001244683
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr20_-_52687303 0.198 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr10_-_52645384 0.197 A1CF
APOBEC1 complementation factor
chr12_+_1017011 0.196 WNK1
WNK lysine deficient protein kinase 1
chr14_+_102276125 0.196 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr13_-_75901897 0.194 TBC1D4
TBC1 domain family, member 4
chr1_+_100316530 0.194 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr19_+_11200037 0.194 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chrX_+_154299674 0.191 NM_001018055
NM_001242640
NM_024332
BRCC3


BRCA1/BRCA2-containing complex, subunit 3


chr6_-_29323971 0.191 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr8_+_110099652 0.189 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr12_+_510740 0.187 NM_001130146
NM_032358
CCDC77

coiled-coil domain containing 77

chrX_-_135962929 0.186 NM_001164803
NM_002139
RBMX

RNA binding motif protein, X-linked

chr11_-_124806302 0.182 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr4_+_41540320 0.181 LIMCH1
LIM and calponin homology domains 1
chr17_-_34417386 0.180 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr6_+_136172802 0.180 NM_018945
PDE7B
phosphodiesterase 7B
chrX_+_102883891 0.177 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr12_+_95676175 0.176 VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_211752052 0.176 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr6_-_24383519 0.175 NM_001195610
DCDC2
doublecortin domain containing 2
chr10_-_99052391 0.175 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr6_-_32977312 0.175 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr14_-_92198383 0.170 NM_024764
CATSPERB
cation channel, sperm-associated, beta
chr10_-_99052429 0.170 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr5_+_161274196 0.170 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_-_19144326 0.170 NM_001017392
NM_014884
SUGP2

SURP and G patch domain containing 2

chr3_-_33700932 0.169 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr11_+_65266980 0.168


chr20_+_42187634 0.168 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_26485510 0.168 NM_024869
FAM110D
family with sequence similarity 110, member D
chr7_+_28530747 0.167 CREB5
cAMP responsive element binding protein 5
chr14_-_23288912 0.166 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_+_41361621 0.164 LIMCH1
LIM and calponin homology domains 1
chr20_+_19915716 0.163 RIN2
Ras and Rab interactor 2
chr19_-_39826676 0.163 NM_004877
GMFG
glia maturation factor, gamma
chr5_+_42548314 0.163 NM_001242403
GHR
growth hormone receptor
chr9_-_117150217 0.162 AKNA
AT-hook transcription factor
chr17_+_48821106 0.162 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr14_-_20774129 0.162 NM_138376
TTC5
tetratricopeptide repeat domain 5
chrX_-_102510048 0.161 NM_001006684
NM_153333
TCEAL8

transcription elongation factor A (SII)-like 8

chr14_-_94789641 0.159 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr5_+_161277702 0.159 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr7_+_80267782 0.159 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr11_+_59824129 0.158 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_-_58603492 0.158 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr3_-_112358758 0.158 CCDC80
coiled-coil domain containing 80
chr2_+_177016112 0.158 NM_014621
HOXD4
homeobox D4
chr12_+_28410132 0.158 NM_018318
CCDC91
coiled-coil domain containing 91
chrX_+_74493893 0.157 NM_145052
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.64 1.77e-03 GO:0005856 cytoskeleton
1.41 9.74e-03 GO:0043228 non-membrane-bounded organelle
1.41 9.74e-03 GO:0043232 intracellular non-membrane-bounded organelle
3.32 2.55e-02 GO:0043292 contractile fiber
2.35 4.43e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.27 5.55e-04 GO:0008092 cytoskeletal protein binding
1.80 7.53e-03 GO:0030234 enzyme regulator activity
2.42 1.36e-02 GO:0003779 actin binding