Motif ID: MYOD1.p2

Z-value: 1.032


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MYOD1chr11_+_17741109-0.145.1e-01Click!


Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_37555055 1.459 FAM83D
family with sequence similarity 83, member D
chr20_+_37554954 1.087 NM_030919
FAM83D
family with sequence similarity 83, member D
chr17_-_39334439 1.053 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr1_-_59248287 1.028 JUN
jun proto-oncogene
chrX_+_118108575 0.995 LONRF3
LON peptidase N-terminal domain and ring finger 3
chrX_+_118108595 0.994 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr10_-_64576123 0.963 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr17_-_39306053 0.960 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr10_-_64576074 0.958 EGR2
early growth response 2
chr5_-_66492574 0.951 NM_005582
CD180
CD180 molecule
chr19_-_49222956 0.926 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chrX_-_13956530 0.925 GPM6B
glycoprotein M6B
chr19_-_7939325 0.882 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chrX_-_152711944 0.870 NM_080701
TREX2
three prime repair exonuclease 2
chr17_-_39324423 0.858 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr12_+_6949374 0.838 NM_002075
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr13_+_100633977 0.834 NM_007129
ZIC2
Zic family member 2
chr8_-_103667882 0.720 NM_005655
KLF10
Kruppel-like factor 10
chr16_+_14013989 0.704 NM_005236
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr1_+_118148668 0.667 FAM46C
family with sequence similarity 46, member C
chr9_-_139637354 0.665 NM_001001712
LCN10
lipocalin 10
chr11_-_1769086 0.634 IFITM10
interferon induced transmembrane protein 10
chr13_-_52980234 0.631 THSD1
thrombospondin, type I, domain containing 1
chr5_+_137801178 0.626 NM_001964
EGR1
early growth response 1
chr17_-_39280377 0.625 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr1_-_40367539 0.607 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr17_-_39341126 0.601 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr10_+_122216465 0.597 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr20_+_58508818 0.589 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr12_+_56075418 0.588 METTL7B
methyltransferase like 7B
chr17_+_39405938 0.582 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr12_+_56075329 0.577 NM_152637
METTL7B
methyltransferase like 7B
chr5_-_172198160 0.559 NM_004417
DUSP1
dual specificity phosphatase 1
chr3_+_133494275 0.556 TF
transferrin
chr19_-_47164289 0.548 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr16_+_23847321 0.546 PRKCB
protein kinase C, beta
chr2_+_219745243 0.540 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr11_+_92702788 0.537 NM_005959
MTNR1B
melatonin receptor 1B
chr17_+_79679399 0.525 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr22_-_21905372 0.524 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr5_+_176560056 0.521 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr10_-_30918625 0.517 NM_183058
LYZL2
lysozyme-like 2
chr11_+_64107687 0.512 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr13_+_113741668 0.511 MCF2L
MCF.2 cell line derived transforming sequence-like
chr10_+_112257624 0.510 NM_004419
DUSP5
dual specificity phosphatase 5
chr22_-_17747520 0.494 CECR3
cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr7_+_17338182 0.492 NM_001621
AHR
aryl hydrocarbon receptor
chr13_-_28194538 0.490 LNX2
ligand of numb-protein X 2
chr1_-_165325474 0.490 NM_001174069
LMX1A
LIM homeobox transcription factor 1, alpha
chr13_-_28194677 0.482 NM_153371
LNX2
ligand of numb-protein X 2
chr1_-_220101514 0.471 SLC30A10
solute carrier family 30, member 10
chr6_+_34204576 0.455 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr17_-_39165343 0.455 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr3_-_122746544 0.452 SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr19_-_6199536 0.445


chr2_+_171572698 0.445 SP5
Sp5 transcription factor
chr5_+_140430960 0.445 NM_013340
PCDHB1
protocadherin beta 1
chr19_+_39687600 0.441 NM_001001414
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr14_-_106237486 0.440


chr1_+_26438267 0.438 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr9_+_17578952 0.437 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr18_-_24220307 0.436 NM_198991
KCTD1
potassium channel tetramerisation domain containing 1
chr14_+_92788924 0.433 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_77659446 0.431


chr1_-_51796230 0.430 TTC39A
tetratricopeptide repeat domain 39A
chr17_+_37894161 0.428 NM_005310
GRB7
growth factor receptor-bound protein 7
chr3_+_101568325 0.424 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chrX_+_118109314 0.424 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr12_+_52416615 0.415 NM_001202233
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr8_-_57123827 0.415 PLAG1
pleiomorphic adenoma gene 1
chr20_+_48599511 0.414 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr19_-_11591439 0.410 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr17_-_39471944 0.408 NM_031964
KRTAP17-1
keratin associated protein 17-1
chr3_-_49158244 0.407 USP19
ubiquitin specific peptidase 19
chr8_+_72756218 0.400 LOC100132891
uncharacterized LOC100132891
chr8_+_72756335 0.397


chr19_-_7990974 0.397 NM_206833
CTXN1
cortexin 1
chr12_+_54378929 0.390 NM_017409
HOXC10
homeobox C10
chr8_-_57123858 0.390 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr11_+_7535213 0.385 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_49158239 0.385 USP19
ubiquitin specific peptidase 19
chr16_+_23847359 0.379 PRKCB
protein kinase C, beta
chr6_+_18387580 0.376 NM_182757
RNF144B
ring finger protein 144B
chr2_-_70781146 0.376 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr16_+_1203240 0.375 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr9_+_130565528 0.372 FPGS
folylpolyglutamate synthase
chr5_+_41904459 0.371 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr10_-_124605690 0.370 NM_022034
CUZD1
CUB and zona pellucida-like domains 1
chr20_+_44098392 0.369 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr17_+_73717556 0.367 ITGB4
integrin, beta 4
chr5_+_173472692 0.365 NM_015980
HMP19
HMP19 protein
chr18_+_77623667 0.359 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr2_-_7005764 0.358 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr3_-_57113292 0.357 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr18_-_46477080 0.356 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr13_+_100634257 0.352 ZIC2
Zic family member 2
chr12_+_49524648 0.352


chr13_-_28543143 0.349 CDX2
caudal type homeobox 2
chr3_-_128294928 0.348 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr1_-_38273852 0.342 NM_024640
YRDC
yrdC domain containing (E. coli)
chr16_+_3162555 0.339 NM_001042428
NM_003456
ZNF205

zinc finger protein 205

chr10_+_92980322 0.338 NM_032373
PCGF5
polycomb group ring finger 5
chr9_+_130565454 0.338 NM_001018078
FPGS
folylpolyglutamate synthase
chr1_+_31885962 0.332 NM_178865
SERINC2
serine incorporator 2
chr10_+_99609994 0.332 NM_001010917
GOLGA7B
golgin A7 family, member B
chr12_+_58013692 0.326 NM_133489
SLC26A10
solute carrier family 26, member 10
chr22_+_21738039 0.324 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr14_-_106208695 0.324


chr19_-_35085489 0.324 NM_001025591
SCGBL
secretoglobin-like
chr11_+_7535000 0.324 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_+_77899857 0.318 NM_020798
USP35
ubiquitin specific peptidase 35
chr17_-_72542148 0.316 CD300C
CD300c molecule
chr3_-_46068978 0.315 NM_001024644
NM_005283
XCR1

chemokine (C motif) receptor 1

chr22_-_50968475 0.314 NM_001113755
NM_001953
TYMP

thymidine phosphorylase

chr2_-_70780621 0.314 TGFA
transforming growth factor, alpha
chr1_-_206945725 0.312 NM_000572
IL10
interleukin 10
chr19_+_13049440 0.310 CALR
calreticulin
chr1_-_153321021 0.310 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chr1_-_38273823 0.309 YRDC
yrdC domain containing (E. coli)
chr1_-_41131113 0.309 RIMS3
regulating synaptic membrane exocytosis 3
chr3_-_123167391 0.308 NM_183357
ADCY5
adenylate cyclase 5
chr5_-_137610112 0.306 NM_001496
GFRA3
GDNF family receptor alpha 3
chr1_+_162039469 0.304 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr2_+_241375235 0.304 GPC1
glypican 1
chr17_+_4981721 0.304 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr19_+_13049413 0.303 NM_004343
CALR
calreticulin
chr19_+_7660698 0.302 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr2_-_154335181 0.301 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr16_-_31439650 0.299 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr11_+_22214574 0.299 NM_001142649
NM_213599
ANO5

anoctamin 5

chr5_-_132948222 0.299 NM_015082
FSTL4
follistatin-like 4
chr17_+_73717515 0.299 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr6_+_106534210 0.299 PRDM1
PR domain containing 1, with ZNF domain
chr5_-_172755418 0.298 STC2
stanniocalcin 2
chr17_-_39211462 0.297 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr1_+_24645811 0.295 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr14_+_100150596 0.288 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr7_-_150675236 0.288 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr17_+_4981754 0.287 ZFP3
zinc finger protein 3 homolog (mouse)
chr18_+_49867069 0.287 DCC
deleted in colorectal carcinoma
chr4_-_21950373 0.285 NM_147182
KCNIP4
Kv channel interacting protein 4
chr17_+_18163836 0.284 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chr4_+_75858205 0.280 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr20_-_23807297 0.280 NM_001322
CST2
cystatin SA
chr10_+_118350470 0.279 NM_006229
PNLIPRP1
pancreatic lipase-related protein 1
chr17_-_21156577 0.278 NM_152914
C17orf103
chromosome 17 open reading frame 103
chr7_+_94292737 0.278 PEG10
paternally expressed 10
chrX_-_43832920 0.278 NM_000266
NDP
Norrie disease (pseudoglioma)
chr16_-_30124829 0.276 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr15_+_76629101 0.275 NM_145805
ISL2
ISL LIM homeobox 2
chr14_-_77608132 0.274 NM_174976
ZDHHC22
zinc finger, DHHC-type containing 22
chr1_-_40782826 0.271 COL9A2
collagen, type IX, alpha 2
chr11_+_7273400 0.271 SYT9
synaptotagmin IX
chr19_+_18747827 0.270 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr4_-_16085309 0.270 PROM1
prominin 1
chr3_+_38080695 0.269 NM_007335
NM_007337
DLEC1

deleted in lung and esophageal cancer 1

chr20_-_62130390 0.266 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr7_-_100171269 0.266 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr22_-_31885512 0.265 NM_001164501
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr13_-_52980628 0.265 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chr10_-_77159851 0.264 ZNF503
zinc finger protein 503
chr7_+_44788453 0.264 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr16_+_23847271 0.264 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr9_-_134615216 0.264 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr11_-_66360485 0.263 NM_018219
CCDC87
coiled-coil domain containing 87
chr7_+_149473130 0.263 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr3_+_8543539 0.262 LMCD1
LIM and cysteine-rich domains 1
chr12_-_49488570 0.262 NM_021044
DHH
desert hedgehog
chr20_-_45976626 0.260 ZMYND8
zinc finger, MYND-type containing 8
chr11_-_796175 0.260 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_-_130298305 0.260 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr12_+_54332575 0.259 NM_017410
HOXC13
homeobox C13
chr9_-_124984018 0.259 NM_001242335
LHX6
LIM homeobox 6
chr1_+_24645914 0.257 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr5_-_134914968 0.256 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr17_-_36105005 0.255 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr1_-_201346783 0.255 TNNT2
troponin T type 2 (cardiac)
chr1_+_37940074 0.255 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr13_+_78271820 0.254 NM_001242868
SLAIN1
SLAIN motif family, member 1
chr9_+_139557378 0.253 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr14_-_65289812 0.253 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr16_-_54318889 0.253 IRX3
iroquois homeobox 3
chr4_-_16085593 0.252 NM_001145847
NM_001145848
PROM1

prominin 1

chr6_+_96463844 0.252 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr18_-_74207145 0.251 NM_014643
ZNF516
zinc finger protein 516
chr19_+_46498695 0.250 CCDC61
coiled-coil domain containing 61
chr2_+_98962617 0.249 NM_001079878
NM_001298
CNGA3

cyclic nucleotide gated channel alpha 3

chr1_-_156675237 0.248 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr1_-_38273846 0.248 YRDC
yrdC domain containing (E. coli)
chr12_+_6833425 0.247 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr19_+_1071208 0.247 HMHA1
histocompatibility (minor) HA-1
chr4_-_6911373 0.246


chr21_+_45285026 0.246 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_22303417 0.245 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chrX_-_152939256 0.245 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr6_+_31582978 0.245 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr1_-_38273683 0.244 YRDC
yrdC domain containing (E. coli)
chr7_-_130418859 0.244 NM_138693
KLF14
Kruppel-like factor 14
chr14_-_106208537 0.243


chr1_+_37940180 0.243 ZC3H12A
zinc finger CCCH-type containing 12A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 3.62e-08 GO:0023052 signaling
1.26 2.50e-07 GO:0048856 anatomical structure development
1.14 1.04e-06 GO:0050789 regulation of biological process
1.13 1.81e-06 GO:0065007 biological regulation
1.26 3.01e-06 GO:0048731 system development
1.37 9.70e-06 GO:0007399 nervous system development
1.20 2.08e-05 GO:0032502 developmental process
1.13 2.09e-05 GO:0050794 regulation of cellular process
1.33 3.99e-05 GO:0023051 regulation of signaling
1.21 4.75e-05 GO:0007165 signal transduction
1.21 1.00e-04 GO:0007275 multicellular organismal development
1.17 5.68e-04 GO:0051716 cellular response to stimulus
1.26 1.15e-03 GO:0030154 cell differentiation
1.44 2.37e-03 GO:0007267 cell-cell signaling
1.24 5.99e-03 GO:0048869 cellular developmental process
1.30 7.08e-03 GO:0009966 regulation of signal transduction
1.28 8.56e-03 GO:0009653 anatomical structure morphogenesis
1.25 1.17e-02 GO:0007166 cell surface receptor linked signaling pathway
1.28 1.39e-02 GO:0065009 regulation of molecular function
1.20 1.44e-02 GO:0048518 positive regulation of biological process
1.53 1.78e-02 GO:0007268 synaptic transmission
1.37 2.28e-02 GO:0048699 generation of neurons
1.33 2.48e-02 GO:0010646 regulation of cell communication
1.35 3.34e-02 GO:0022008 neurogenesis
1.32 4.51e-02 GO:0007154 cell communication
1.47 4.87e-02 GO:0019226 transmission of nerve impulse
1.47 4.87e-02 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 7.63e-05 GO:0044459 plasma membrane part
2.16 1.20e-02 GO:0045095 keratin filament
1.38 3.25e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 5.13e-03 GO:0005515 protein binding