Motif ID: NFIL3.p2

Z-value: 0.665


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NFIL3chr9_-_94186140-0.048.5e-01Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74702272 3.280 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr12_-_105322056 2.807 NM_032148
SLC41A2
solute carrier family 41, member 2
chr6_-_29527477 2.105 UBD
ubiquitin D
chr10_+_91087601 1.885 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr8_+_17396285 1.762 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr11_-_64647136 1.455 EHD1
EH-domain containing 1
chr1_+_212738675 1.357 NM_001030287
ATF3
activating transcription factor 3
chr13_+_97874704 1.135 MBNL2
muscleblind-like 2 (Drosophila)
chr10_-_14372807 1.024 NM_018027
FRMD4A
FERM domain containing 4A
chr3_-_78666943 1.024 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_-_76928601 0.996 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr13_+_97928414 0.922 MBNL2
muscleblind-like 2 (Drosophila)
chr21_+_27011588 0.910 NM_021219
JAM2
junctional adhesion molecule 2
chr17_-_41623246 0.898 NM_001986
ETV4
ets variant 4
chr17_-_41623652 0.871 NM_001079675
ETV4
ets variant 4
chr7_+_28725597 0.807 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr21_+_45138987 0.797 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr20_+_58296264 0.781 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr3_-_194188967 0.752 NM_024524
ATP13A3
ATPase type 13A3
chr4_-_153273683 0.734 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr12_+_124773709 0.722 NM_181709
FAM101A
family with sequence similarity 101, member A
chr2_-_224903324 0.658 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr22_-_36562224 0.649 NM_145641
NM_145642
APOL3

apolipoprotein L, 3

chr17_-_63009302 0.625 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr10_+_118305427 0.601 NM_000936
PNLIP
pancreatic lipase
chr10_+_97759847 0.591 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr5_+_125695787 0.568 NM_001146319
GRAMD3
GRAM domain containing 3
chr2_-_31637553 0.557 XDH
xanthine dehydrogenase
chr21_+_45138973 0.548 NM_003681
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr2_-_214015053 0.541 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr22_-_50523853 0.519 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_+_40996596 0.509 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr5_-_32388595 0.482 ZFR
zinc finger RNA binding protein
chr7_-_31380507 0.481 NM_022728
NEUROD6
neurogenic differentiation 6
chr10_-_69455926 0.478 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr20_+_2082527 0.478 NM_080836
STK35
serine/threonine kinase 35
chr17_-_39306053 0.470 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr6_+_7402879 0.467 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr11_+_5710926 0.461 TRIM22
tripartite motif containing 22
chr4_-_69536314 0.461 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_-_113206883 0.451 NM_052864
TIFA
TRAF-interacting protein with forkhead-associated domain
chr3_+_133494275 0.433 TF
transferrin
chr1_-_156721280 0.426 HDGF
hepatoma-derived growth factor
chr14_+_24563369 0.421 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr3_-_196911001 0.414 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr8_+_94929991 0.413 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_25757381 0.410 NM_018202
TMEM57
transmembrane protein 57
chr13_+_97874540 0.408 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr5_-_158634641 0.402 NM_001199382
RNF145
ring finger protein 145
chr17_-_39254374 0.399 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr22_+_50925212 0.394 NM_017584
MIOX
myo-inositol oxygenase
chr13_-_33780142 0.390 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr11_+_35639734 0.387 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr19_+_3762671 0.378 MRPL54
mitochondrial ribosomal protein L54
chr17_-_61850953 0.374 NM_020198
CCDC47
coiled-coil domain containing 47
chr20_-_47894591 0.374 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr6_-_136847609 0.373 MAP7
microtubule-associated protein 7
chr9_-_19786886 0.370 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr2_-_175712276 0.369 NM_001206602
CHN1
chimerin (chimaerin) 1
chr7_-_112727832 0.363 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr10_+_135340865 0.360 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_+_74269971 0.360 NM_000477
ALB
albumin
chr5_-_58882274 0.359 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_3762650 0.355 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr5_-_94417185 0.354 MCTP1
multiple C2 domains, transmembrane 1
chr14_+_94577078 0.351 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr2_-_128100673 0.348 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr11_+_69061599 0.345 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr12_-_89920038 0.340 NM_001199781
NM_001199782
NM_172240
POC1B-GALNT4

POC1B
POC1B-GALNT4 readthrough

POC1 centriolar protein homolog B (Chlamydomonas)
chr3_-_123339178 0.337 MYLK
myosin light chain kinase
chr2_-_74753311 0.334 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr2_-_167005641 0.334 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr8_-_90996884 0.332 NM_002485
NBN
nibrin
chr2_+_135676409 0.327 CCNT2
cyclin T2
chr15_-_49255640 0.323 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_11249344 0.319 NM_021146
ANGPTL7
angiopoietin-like 7
chr3_+_187086167 0.300 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr17_-_61850890 0.298 CCDC47
coiled-coil domain containing 47
chr5_-_137848517 0.296 ETF1
eukaryotic translation termination factor 1
chr1_+_50575465 0.294 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_41984888 0.292 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr17_-_29648631 0.291 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr7_-_112727799 0.284 GPR85
G protein-coupled receptor 85
chr14_+_72399785 0.284 NM_001204416
NM_001204417
NM_001204418
NM_001204419
NM_001204420
NM_001204421
NM_001204422
NM_004296
RGS6







regulator of G-protein signaling 6







chr4_+_55095433 0.283 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_-_21368005 0.281 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr2_-_239197091 0.279 NM_022817
PER2
period homolog 2 (Drosophila)
chr6_-_13295817 0.276 NM_001242698
LOC100130357
uncharacterized LOC100130357
chr17_-_39324423 0.274 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr3_+_63953419 0.263 NM_001128149
ATXN7
ataxin 7
chr12_-_16759430 0.262 LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_117799410 0.256 NM_000620
NM_001204218
NOS1

nitric oxide synthase 1 (neuronal)

chr17_-_67240955 0.250 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr6_+_131894343 0.248 NM_000045
NM_001244438
ARG1

arginase, liver

chr10_-_104211244 0.246 NM_024886
C10orf95
chromosome 10 open reading frame 95
chr10_+_18549583 0.239 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr22_-_29457793 0.239 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr17_+_39261640 0.239 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr4_+_71494460 0.238 NM_031889
ENAM
enamelin
chr15_-_83621350 0.238 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr17_+_39240412 0.236 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr8_+_120079423 0.235 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr17_-_39274587 0.232 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr7_-_107443631 0.227 NM_000111
SLC26A3
solute carrier family 26, member 3
chr1_-_178840079 0.225 NM_004673
ANGPTL1
angiopoietin-like 1
chr16_-_755718 0.225 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr18_+_32621299 0.223 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_57320442 0.223 NM_000562
C8A
complement component 8, alpha polypeptide
chr10_-_69425356 0.221 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr5_-_158635080 0.218 NM_001199381
RNF145
ring finger protein 145
chr21_+_19617145 0.218 NM_024944
CHODL
chondrolectin
chr19_-_41388656 0.216 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr15_-_56209305 0.215 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr7_-_142659397 0.214 KEL
Kell blood group, metallo-endopeptidase
chr13_-_20110884 0.211 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr9_+_111624545 0.210 NM_006687
ACTL7A
actin-like 7A
chr17_-_19651586 0.209 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr12_-_16757944 0.203 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_155006281 0.202 NM_001143687
NM_152494
DCST1

DC-STAMP domain containing 1

chr4_+_71200670 0.202 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr7_-_83824216 0.198 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_-_87969135 0.190 LINC00461
long intergenic non-protein coding RNA 461
chr19_+_41594367 0.190 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr3_+_128532267 0.190


chr3_-_99833348 0.190 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr2_+_161993465 0.187 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr18_+_21572736 0.185 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr1_+_65613211 0.184 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr14_+_62462540 0.183 NM_031914
SYT16
synaptotagmin XVI
chr22_-_50221195 0.182 BRD1
bromodomain containing 1
chr19_+_44455379 0.181 NM_013359
ZNF221
zinc finger protein 221
chr5_-_146435589 0.180 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr9_-_73029539 0.179 NM_001206
KLF9
Kruppel-like factor 9
chr15_-_90222572 0.172 NM_001145311
NM_002666
PLIN1

perilipin 1

chr14_-_67826414 0.172 NM_015994
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chrX_-_102531673 0.170 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr12_-_52867521 0.170 NM_173086
KRT6C
keratin 6C
chr11_-_119599253 0.170 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr14_-_70263871 0.168 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr17_+_51900238 0.168 NM_032559
KIF2B
kinesin family member 2B
chr10_-_99790346 0.167 CRTAC1
cartilage acidic protein 1
chr7_-_142659412 0.164 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr10_+_98064084 0.164 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chr21_+_45139169 0.164 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr18_-_40857245 0.164 NM_020783
SYT4
synaptotagmin IV
chr1_+_206808751 0.163 NM_001004023
NM_003582
DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr8_-_102217519 0.162 ZNF706
zinc finger protein 706
chr22_+_42086546 0.161 NM_001142964
C22orf46
chromosome 22 open reading frame 46
chr12_-_53074172 0.161 NM_006121
KRT1
keratin 1
chr8_-_72274466 0.161 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr10_+_124151818 0.161 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_-_136847078 0.160 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr7_+_134464161 0.157 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr1_-_153348057 0.157 NM_005621
S100A12
S100 calcium binding protein A12
chr17_-_26941178 0.157 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr10_+_86004808 0.156 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr4_-_70080448 0.154 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chrX_+_135730335 0.154 NM_000074
CD40LG
CD40 ligand
chr2_-_71047678 0.153 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr10_+_70847817 0.151 NM_002727
SRGN
serglycin
chr10_+_95848811 0.151 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr9_-_123639566 0.151 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr13_-_70682458 0.151 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr17_+_61851512 0.145


chr3_-_123339423 0.142 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr3_+_186383770 0.141 NM_000412
HRG
histidine-rich glycoprotein
chr1_+_149804220 0.141 NM_001034077
NM_003548
HIST2H4B
HIST2H4A
histone cluster 2, H4b
histone cluster 2, H4a
chr2_-_174767282 0.139


chr10_-_94257470 0.138 NM_001165946
IDE
insulin-degrading enzyme
chr6_-_27835308 0.136 NM_005322
HIST1H1B
histone cluster 1, H1b
chr9_+_71819926 0.134 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr16_-_30103204 0.131 NM_004608
TBX6
T-box 6
chr8_-_110661007 0.131 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr16_+_31711914 0.129 KIAA0664L3
KIAA0664-like 3
chr1_+_158259558 0.129 NM_001765
CD1C
CD1c molecule
chr7_+_90032647 0.128 NM_001185072
NM_001185073
NM_012129
CLDN12


claudin 12


chr18_+_21032786 0.126 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr2_+_131862419 0.126 NM_001100623
NM_017958
PLEKHB2

pleckstrin homology domain containing, family B (evectins) member 2

chr2_-_178753464 0.126 NM_001077196
PDE11A
phosphodiesterase 11A
chr6_-_57086204 0.126 NM_183227
RAB23
RAB23, member RAS oncogene family
chr9_-_123639462 0.124 PHF19
PHD finger protein 19
chr3_-_48130283 0.123 MAP4
microtubule-associated protein 4
chr2_+_154728424 0.122 NM_052917
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr12_-_88423145 0.121 NM_152589
C12orf50
chromosome 12 open reading frame 50
chr19_-_35992798 0.120 NM_001035516
DMKN
dermokine
chr17_-_38821286 0.119 NM_152349
KRT222
keratin 222
chr6_+_64231626 0.119 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_99594915 0.116 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr21_-_40816127 0.116 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr1_-_203155745 0.115 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_-_94417544 0.115 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_7382750 0.113 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr12_-_91505215 0.113 LUM
lumican
chr10_-_52645430 0.113 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr7_-_112726143 0.112 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr17_+_26800657 0.111 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr14_+_32798478 0.110 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr16_+_2732526 0.109 KCTD5
potassium channel tetramerisation domain containing 5
chr10_+_70847857 0.109 SRGN
serglycin
chr3_+_130569368 0.107 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.92 4.59e-04 GO:0045095 keratin filament
2.01 1.53e-03 GO:0044421 extracellular region part
1.64 2.79e-03 GO:0005576 extracellular region
2.01 1.64e-02 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
9.45 1.01e-02 GO:0015020 glucuronosyltransferase activity