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• Activity deltas table
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Motif ID: NFKB1_REL_RELA.p2

Z-value: 6.611

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_4229494	62.747	NM_005755	EBI3	Epstein-Barr virus induced 3
chr6_-_29527701	45.285	NM_006398	UBD	ubiquitin D
chr4_-_120549115	44.814	NM_033437	PDE5A	phosphodiesterase 5A, cGMP-specific
chr4_-_76944585	43.598	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr6_-_29527477	42.988		UBD	ubiquitin D
chr10_+_104154228	41.808	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_+_50776012	38.943	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr1_+_101185195	37.018	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr10_+_104155431	36.937	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr5_-_150466696	35.943	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr16_+_50775960	35.624	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr19_+_45504686	34.019	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr4_+_74702272	32.258	NM_002993	CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr11_+_102188180	31.760	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr2_+_228678556	31.655	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr4_+_103422730	29.876		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_-_76957139	29.536	NM_005409	CXCL11	chemokine (C-X-C motif) ligand 11
chr1_-_184943532	28.268		FAM129A	family with sequence similarity 129, member A
chr4_+_103422822	25.440		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422479	24.723	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_+_40440481	24.699		STAT5A	signal transducer and activator of transcription 5A
chr2_-_163174816	24.432	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr1_-_169703178	23.423	NM_000450	SELE	selectin E
chr21_+_27011588	23.221	NM_021219	JAM2	junctional adhesion molecule 2
chr5_+_10564431	23.000	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr5_-_150460599	22.477	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr5_-_150467220	22.364	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chr4_+_103422553	22.247		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr5_-_150460550	22.154		TNIP1	TNFAIP3 interacting protein 1
chr19_-_4338750	22.069	NM_001013841 NM_017720	STAP2	signal transducing adaptor family member 2
chr15_+_67430358	22.062	NM_001145103	SMAD3	SMAD family member 3
chr8_+_90769974	21.934	NM_003821	RIPK2	receptor-interacting serine-threonine kinase 2
chr4_+_142557722	21.490	NM_000585 NM_172175	IL15	interleukin 15
chr14_-_24616429	21.144		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr22_-_19512859	21.099	NM_001130861 NM_003277	CLDN5	claudin 5
chr15_+_89182038	20.735	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr4_-_74864296	20.403	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr6_+_14117486	20.010	NM_001251901	CD83	CD83 molecule
chr12_-_49259549	19.929	NM_014470	RND1	Rho family GTPase 1
chr1_+_110453232	19.685	NM_000757 NM_172210 NM_172212	CSF1	colony stimulating factor 1 (macrophage)
chr5_-_131826426	19.250	NM_002198	IRF1	interferon regulatory factor 1
chr1_+_110453456	18.930		CSF1	colony stimulating factor 1 (macrophage)
chr4_-_120549827	18.733	NM_001083	PDE5A	phosphodiesterase 5A, cGMP-specific
chr14_-_35873823	17.849	NM_020529	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr21_+_27011766	17.223		JAM2	junctional adhesion molecule 2
chr9_+_115913266	17.169		SLC31A2	solute carrier family 31 (copper transporters), member 2
chr1_-_209825797	17.071	NM_000228	LAMB3	laminin, beta 3
chr21_+_27012067	16.795		JAM2	junctional adhesion molecule 2
chr3_+_53195214	16.644	NM_006254 NM_212539	PRKCD	protein kinase C, delta
chr19_-_17958773	16.442		JAK3	Janus kinase 3
chr1_-_209824641	16.245	NM_001017402	LAMB3	laminin, beta 3
chr11_-_3862137	16.229		RHOG	ras homolog gene family, member G (rho G)
chr20_+_44746889	16.048	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr6_-_31324975	15.989	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr18_-_71959109	15.675	NM_001190807 NM_001914 NM_148923	CYB5A	cytochrome b5 type A (microsomal)
chr8_+_90770201	15.515		RIPK2	receptor-interacting serine-threonine kinase 2
chr8_+_23386362	15.468	NM_016612	SLC25A37	solute carrier family 25, member 37
chr6_+_14118002	15.278		CD83	CD83 molecule
chr8_+_23386386	15.115		SLC25A37	solute carrier family 25, member 37
chr5_+_31639424	14.918		PDZD2	PDZ domain containing 2
chr7_+_18548899	14.313	NM_001204147 NM_001204148	HDAC9	histone deacetylase 9
chr6_-_31324955	14.148		HLA-B	major histocompatibility complex, class I, B
chr9_-_136344182	13.994	NM_001145099 NM_017585	SLC2A6	solute carrier family 2 (facilitated glucose transporter), member 6
chr11_+_118307072	13.958	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr5_-_179780314	13.818	NM_005110	GFPT2	glutamine-fructose-6-phosphate transaminase 2
chr11_+_122526339	13.707	NM_032873	UBASH3B	ubiquitin associated and SH3 domain containing B
chr4_+_74735107	13.289	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr6_+_29910246	12.945	NM_001242758 NM_002116	HLA-A	major histocompatibility complex, class I, A
chr14_+_103243813	12.735	NM_001199427 NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr10_+_12391708	12.688		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr2_+_237478379	12.686	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr19_-_47734215	12.408	NM_014417	BBC3	BCL2 binding component 3
chr6_+_80340971	12.243	NM_031469	SH3BGRL2	SH3 domain binding glutamic acid-rich protein like 2
chr2_+_208394823	12.232		CREB1	cAMP responsive element binding protein 1
chr19_+_45251933	12.158	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr14_+_103243832	12.112		TRAF3	TNF receptor-associated factor 3
chr17_-_34207308	11.892	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr1_-_153521717	11.842	NM_002960	S100A3	S100 calcium binding protein A3
chr4_+_154605441	11.816		TLR2	toll-like receptor 2
chr12_-_57504088	11.505	NM_001178079	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr15_+_67358161	11.381		SMAD3	SMAD family member 3
chr6_-_31324898	11.342		HLA-B	major histocompatibility complex, class I, B
chr14_-_24615772	11.275		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_+_208394692	11.190		CREB1	cAMP responsive element binding protein 1
chr6_+_138188352	11.080	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr5_-_95297424	11.044		ELL2	elongation factor, RNA polymerase II, 2
chr2_+_208394756	11.033		CREB1	cAMP responsive element binding protein 1
chr16_+_50731049	10.889	NM_022162	NOD2	nucleotide-binding oligomerization domain containing 2
chr6_+_29974352	10.845		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr21_+_34775740	10.821		IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_-_117568292	10.799	NM_005118	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chr4_-_185395616	10.751	NM_002199	IRF2	interferon regulatory factor 2
chr4_+_154605421	10.559	NM_003264	TLR2	toll-like receptor 2
chr1_-_95007139	10.557	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr4_-_122085475	10.543	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr14_-_24615794	10.538	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_-_3862183	10.363	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr4_-_120550142	10.319
chr1_-_173020011	10.317	NM_005092	TNFSF18	tumor necrosis factor (ligand) superfamily, member 18
chr20_+_44746948	10.258		CD40	CD40 molecule, TNF receptor superfamily member 5
chr18_+_23806385	10.225	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr21_+_34775729	10.204		IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr11_-_57335756	10.150	NM_198183	UBE2L6	ubiquitin-conjugating enzyme E2L 6
chr21_+_34775189	10.126	NM_005534	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr3_-_79068542	9.898	NM_001145845 NM_133631	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_+_13142055	9.774	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr4_-_146859568	9.726	NM_178835	ZNF827	zinc finger protein 827
chr21_+_26934440	9.629		MIR155HG	MIR155 host gene (non-protein coding)
chr5_+_131593377	9.619		PDLIM4	PDZ and LIM domain 4
chr4_-_74904329	9.596	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr4_-_122148620	9.592	NM_001244764	TNIP3	TNFAIP3 interacting protein 3
chr5_+_131409484	9.537	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr10_+_12391471	9.489	NM_020397 NM_153498	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr21_+_27012045	9.488		JAM2	junctional adhesion molecule 2
chr17_+_74381186	9.410	NM_001142602	SPHK1	sphingosine kinase 1
chr6_+_116692098	9.320	NM_013352	DSE	dermatan sulfate epimerase
chr11_-_8832189	9.240	NM_213618	ST5	suppression of tumorigenicity 5
chr6_+_149639435	9.207	NM_015093	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr11_-_57089670	9.111		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr2_+_208394615	9.035	NM_004379 NM_134442	CREB1	cAMP responsive element binding protein 1
chr16_+_3115611	8.948	NM_001012635	IL32	interleukin 32
chr20_+_814355	8.932	NM_001042353	FAM110A	family with sequence similarity 110, member A
chr5_+_170846659	8.854	NM_003862	FGF18	fibroblast growth factor 18
chr17_+_74381419	8.737		SPHK1	sphingosine kinase 1
chr4_-_74964996	8.708	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr2_+_32853086	8.686	NM_001193509 NM_017735	TTC27	tetratricopeptide repeat domain 27
chr16_+_3115312	8.664	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr5_-_141338626	8.591	NM_016580	PCDH12	protocadherin 12
chr19_+_41725277	8.588		AXL	AXL receptor tyrosine kinase
chr6_+_149639054	8.572		TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr4_+_139936938	8.521	NM_012118	CCRN4L	CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr16_+_3115638	8.396	NM_001012634	IL32	interleukin 32
chr17_+_21191347	8.349	NM_002756	MAP2K3	mitogen-activated protein kinase kinase 3
chr16_+_3115639	8.282		IL32	interleukin 32
chr6_+_106534188	8.273	NM_001198	PRDM1	PR domain containing 1, with ZNF domain
chr1_-_32281577	8.225	NM_144569	SPOCD1	SPOC domain containing 1
chr6_-_31324564	8.191		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr3_+_9691198	8.180		MTMR14	myotubularin related protein 14
chr2_+_68694669	8.146	NM_173545	APLF	aprataxin and PNKP like factor
chr5_+_131593331	8.138	NM_001131027 NM_003687	PDLIM4	PDZ and LIM domain 4
chr12_+_100661158	7.918		SCYL2	SCY1-like 2 (S. cerevisiae)
chr2_+_219745243	7.865	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr6_+_44094650	7.809		TMEM63B	transmembrane protein 63B
chr5_-_54830369	7.723	NM_003711 NM_176895	RNF138P1 PPAP2A	ring finger protein 138 pseudogene 1 phosphatidic acid phosphatase type 2A
chr9_+_72658496	7.689	NM_153267	MAMDC2	MAM domain containing 2
chr15_+_44719831	7.671		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr12_+_100660846	7.655		SCYL2	SCY1-like 2 (S. cerevisiae)
chr6_+_37137882	7.599	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr19_+_39390258	7.598	NM_001243116	NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr15_-_64338519	7.524	NM_014326	DAPK2	death-associated protein kinase 2
chr15_+_67358194	7.507	NM_005902	SMAD3	SMAD family member 3
chr7_+_151038808	7.352	NM_001243351 NM_016118	NUB1	negative regulator of ubiquitin-like proteins 1
chr8_+_86157693	7.329	NM_198584	CA13	carbonic anhydrase XIII
chr9_+_116918230	7.314	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr14_+_70078313	7.299		KIAA0247	KIAA0247
chr15_+_44719765	7.289		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr19_+_39390618	7.270		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr9_+_132934685	7.267	NM_014286	NCS1	neuronal calcium sensor 1
chr3_+_9691116	7.229	NM_001077525 NM_001077526 NM_022485	MTMR14	myotubularin related protein 14
chr5_-_58334936	7.214	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr3_-_71632741	7.199	NM_001244808 NM_001012505 NM_001244810 NM_032682	FOXP1	forkhead box P1
chr19_+_45582469	7.181	NM_001007270 NM_001007269 NM_024707	GEMIN7	gem (nuclear organelle) associated protein 7
chr9_+_72658735	7.161		MAMDC2	MAM domain containing 2
chr14_+_24616095	7.145		RNF31	ring finger protein 31
chr6_+_14117857	7.145	NM_001040280 NM_004233	CD83	CD83 molecule
chr3_+_9691184	7.124		MTMR14	myotubularin related protein 14
chr3_-_45267804	7.110	NM_015444	TMEM158	transmembrane protein 158 (gene/pseudogene)
chr19_+_19322763	7.008	NM_004386	NCAN	neurocan
chr3_-_45267620	6.980		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr10_+_30722856	6.970	NM_001244134 NM_005204	MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr11_-_58910207	6.885
chr11_-_128392061	6.881	NM_001162422 NM_005238	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr6_+_36646455	6.750	NM_000389 NM_001220778	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr11_+_93862060	6.733	NM_015368	PANX1	pannexin 1
chr8_+_145149985	6.712		CYC1	cytochrome c-1
chr1_+_183155393	6.649		LAMC2	laminin, gamma 2
chr19_-_17958814	6.619	NM_000215	JAK3	Janus kinase 3
chr22_+_31644314	6.595	NM_001031801 NM_016733	LIMK2	LIM domain kinase 2
chr3_-_37217716	6.594	NM_001134369 NM_006309 NM_017724	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2
chr5_+_131593388	6.572		PDLIM4	PDZ and LIM domain 4
chr11_-_75062650	6.489	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr19_+_41725135	6.453		AXL	AXL receptor tyrosine kinase
chr7_-_131241321	6.436	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr7_-_105925329	6.433		NAMPT	nicotinamide phosphoribosyltransferase
chr1_-_212873306	6.363	NM_018664	BATF3	basic leucine zipper transcription factor, ATF-like 3
chr1_+_100818052	6.249		CDC14A	CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr6_+_29855506	6.249
chr11_+_93862143	6.249		PANX1	pannexin 1
chr19_+_496453	6.203	NM_130760 NM_130762	MADCAM1	mucosal vascular addressin cell adhesion molecule 1
chr2_+_26568900	6.174	NM_033505	EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr1_+_165796652	6.154	NM_012474	UCK2	uridine-cytidine kinase 2
chr19_+_41725131	6.149		AXL	AXL receptor tyrosine kinase
chr12_-_50101192	6.126	NM_175736 NM_198900	FMNL3	formin-like 3
chr11_+_35639734	6.096	NM_014344	FJX1	four jointed box 1 (Drosophila)
chr6_-_82462374	6.089	NM_017633	FAM46A	family with sequence similarity 46, member A
chr4_+_77870944	6.077		SEPT11	septin 11
chr1_-_89664510	6.068	NM_052941	GBP4	guanylate binding protein 4
chr1_-_1822501	6.060		GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_-_247242026	6.028		ZNF670	zinc finger protein 670
chr18_+_55711890	6.024		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.53	4.52e-13	GO:0048522	positive regulation of cellular process
1.47	7.38e-12	GO:0048518	positive regulation of biological process
1.23	2.73e-10	GO:0050794	regulation of cellular process
1.69	1.05e-09	GO:0002376	immune system process
1.13	1.52e-09	GO:0009987	cellular process
1.87	1.21e-08	GO:0006955	immune response
1.20	2.12e-08	GO:0050789	regulation of biological process
1.66	4.07e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.62	6.13e-08	GO:0009893	positive regulation of metabolic process
1.18	7.29e-08	GO:0065007	biological regulation
1.43	1.11e-07	GO:0048519	negative regulation of biological process
1.62	2.28e-07	GO:0031325	positive regulation of cellular metabolic process
1.31	2.49e-07	GO:0023052	signaling
1.84	6.75e-07	GO:0010628	positive regulation of gene expression
1.65	1.31e-06	GO:0042981	regulation of apoptosis
1.42	1.54e-06	GO:0048523	negative regulation of cellular process
1.32	1.55e-06	GO:0007165	signal transduction
1.77	1.81e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.63	2.43e-06	GO:0043067	regulation of programmed cell death
1.62	4.11e-06	GO:0010941	regulation of cell death
2.16	7.51e-06	GO:0031347	regulation of defense response
1.79	2.14e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.30	2.72e-05	GO:0060255	regulation of macromolecule metabolic process
1.60	4.47e-05	GO:0009605	response to external stimulus
1.59	6.02e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.54	7.46e-05	GO:0031349	positive regulation of defense response
1.62	1.11e-04	GO:0040011	locomotion
1.89	1.16e-04	GO:0002684	positive regulation of immune system process
1.86	1.29e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.63	1.50e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.69	1.64e-04	GO:0002682	regulation of immune system process
1.64	2.13e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.61	2.17e-04	GO:0009891	positive regulation of biosynthetic process
1.81	2.41e-04	GO:0006935	chemotaxis
1.81	2.41e-04	GO:0042330	taxis
1.26	2.57e-04	GO:0031323	regulation of cellular metabolic process
1.24	2.75e-04	GO:0051716	cellular response to stimulus
2.41	3.74e-04	GO:0045088	regulation of innate immune response
1.69	4.05e-04	GO:0051254	positive regulation of RNA metabolic process
2.10	4.37e-04	GO:0001817	regulation of cytokine production
1.63	4.85e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	8.01e-04	GO:0010468	regulation of gene expression
1.33	9.37e-04	GO:0042221	response to chemical stimulus
1.31	9.91e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.24	9.94e-04	GO:0019222	regulation of metabolic process
1.32	1.22e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.24	1.24e-03	GO:0034130	toll-like receptor 1 signaling pathway
3.24	1.24e-03	GO:0034134	toll-like receptor 2 signaling pathway
1.59	1.26e-03	GO:0048584	positive regulation of response to stimulus
3.28	1.77e-03	GO:0002756	MyD88-independent toll-like receptor signaling pathway
3.08	1.94e-03	GO:0008063	Toll signaling pathway
3.08	1.94e-03	GO:0034142	toll-like receptor 4 signaling pathway
1.24	2.75e-03	GO:0080090	regulation of primary metabolic process
1.92	2.93e-03	GO:0007411	axon guidance
1.26	3.22e-03	GO:0048856	anatomical structure development
1.36	3.31e-03	GO:0006464	protein modification process
3.06	3.66e-03	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.55	4.38e-03	GO:0006952	defense response
3.23	4.47e-03	GO:0034138	toll-like receptor 3 signaling pathway
2.87	4.51e-03	GO:0002224	toll-like receptor signaling pathway
2.52	4.90e-03	GO:0045089	positive regulation of innate immune response
1.64	5.02e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.28	5.05e-03	GO:0031326	regulation of cellular biosynthetic process
2.76	5.97e-03	GO:0002758	innate immune response-activating signal transduction
1.16	6.24e-03	GO:0050896	response to stimulus
1.75	6.71e-03	GO:0050776	regulation of immune response
1.39	6.80e-03	GO:0065009	regulation of molecular function
2.29	7.23e-03	GO:0051272	positive regulation of cellular component movement
1.51	7.30e-03	GO:0050793	regulation of developmental process
1.71	8.41e-03	GO:0000904	cell morphogenesis involved in differentiation
1.49	8.96e-03	GO:0042127	regulation of cell proliferation
2.70	9.15e-03	GO:0002218	activation of innate immune response
1.27	9.67e-03	GO:0009889	regulation of biosynthetic process
2.23	1.05e-02	GO:0051251	positive regulation of lymphocyte activation
1.60	1.06e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
2.74	1.10e-02	GO:0002221	pattern recognition receptor signaling pathway
1.30	1.35e-02	GO:0051252	regulation of RNA metabolic process
1.20	1.39e-02	GO:0044260	cellular macromolecule metabolic process
1.99	1.43e-02	GO:0090046	regulation of transcription regulator activity
1.33	1.50e-02	GO:0048583	regulation of response to stimulus
1.85	1.53e-02	GO:0045597	positive regulation of cell differentiation
1.30	1.67e-02	GO:0006355	regulation of transcription, DNA-dependent
1.66	1.69e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.64	1.86e-02	GO:0006928	cellular component movement
1.66	1.94e-02	GO:0080134	regulation of response to stress
1.71	1.98e-02	GO:0051094	positive regulation of developmental process
1.57	1.99e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.98	2.06e-02	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
1.76	2.14e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.37	2.21e-02	GO:0009653	anatomical structure morphogenesis
2.14	2.23e-02	GO:0002696	positive regulation of leukocyte activation
1.18	2.26e-02	GO:0043170	macromolecule metabolic process
2.85	2.33e-02	GO:0002699	positive regulation of immune effector process
1.60	2.37e-02	GO:0010629	negative regulation of gene expression
1.21	2.46e-02	GO:0032502	developmental process
2.24	2.51e-02	GO:0040017	positive regulation of locomotion
1.89	2.58e-02	GO:0051270	regulation of cellular component movement
1.72	2.65e-02	GO:0043066	negative regulation of apoptosis
1.70	2.77e-02	GO:0060548	negative regulation of cell death
1.25	2.81e-02	GO:0048731	system development
1.56	3.01e-02	GO:0045595	regulation of cell differentiation
1.27	3.10e-02	GO:0044267	cellular protein metabolic process
1.71	3.14e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.65	3.29e-02	GO:0043065	positive regulation of apoptosis
2.10	3.34e-02	GO:0050867	positive regulation of cell activation
1.86	3.41e-02	GO:0051130	positive regulation of cellular component organization
2.01	3.43e-02	GO:0051249	regulation of lymphocyte activation
1.72	3.54e-02	GO:0007409	axonogenesis
1.62	3.64e-02	GO:0051253	negative regulation of RNA metabolic process
1.82	3.68e-02	GO:0051098	regulation of binding
1.70	3.71e-02	GO:0043069	negative regulation of programmed cell death
1.90	3.89e-02	GO:0051101	regulation of DNA binding
1.65	4.11e-02	GO:0009967	positive regulation of signal transduction
1.64	4.14e-02	GO:0043068	positive regulation of programmed cell death
1.44	4.27e-02	GO:0032268	regulation of cellular protein metabolic process
2.82	4.34e-02	GO:0045785	positive regulation of cell adhesion
2.28	4.44e-02	GO:0050870	positive regulation of T cell activation
1.31	4.46e-02	GO:0043412	macromolecule modification
1.54	4.72e-02	GO:0009890	negative regulation of biosynthetic process
1.54	4.72e-02	GO:0030182	neuron differentiation
1.51	4.91e-02	GO:2000026	regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.30	1.39e-03	GO:0044459	plasma membrane part
10.16	4.34e-03	GO:0033256	I-kappaB/NF-kappaB complex
1.11	9.14e-03	GO:0005737	cytoplasm
1.18	1.79e-02	GO:0071944	cell periphery
1.18	1.86e-02	GO:0005886	plasma membrane
1.26	3.29e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	9.54e-12	GO:0005515	protein binding
2.26	5.43e-04	GO:0005126	cytokine receptor binding
1.49	1.07e-03	GO:0001071	nucleic acid binding transcription factor activity
1.49	1.07e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
2.10	3.94e-03	GO:0005125	cytokine activity
1.07	6.59e-03	GO:0005488	binding
3.19	1.45e-02	GO:0042379	chemokine receptor binding
3.31	1.57e-02	GO:0008009	chemokine activity
1.50	2.99e-02	GO:0043565	sequence-specific DNA binding