Motif ID: NRF1.p2

Z-value: 1.764


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NRF1chr7_+_129251579-0.271.9e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_50432672 1.820 IL4I1
interleukin 4 induced 1
chr19_-_50432647 1.735 IL4I1
interleukin 4 induced 1
chr5_+_52095929 1.605 PELO
pelota homolog (Drosophila)
chr9_+_110045551 1.457 RAD23B
RAD23 homolog B (S. cerevisiae)
chr6_-_41040160 1.388 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr19_-_7968426 1.378


chr7_-_44621837 1.250 TMED4
transmembrane emp24 protein transport domain containing 4
chr19_+_11071713 1.189 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr15_+_41952641 1.183 MGA
MAX gene associated
chr19_+_11071719 1.157 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr9_+_110045565 1.134 RAD23B
RAD23 homolog B (S. cerevisiae)
chr10_+_60028885 1.128 NM_018464
CISD1
CDGSH iron sulfur domain 1
chr19_+_3762671 1.057 MRPL54
mitochondrial ribosomal protein L54
chr19_+_42724498 1.020 ZNF526
zinc finger protein 526
chr9_+_37079984 0.981 LOC100506710
endogenous Bornavirus-like nucleoprotein 2 pseudogene
chr7_-_44621784 0.977 TMED4
transmembrane emp24 protein transport domain containing 4
chr18_-_12884140 0.968 NM_001207013
NM_002828
NM_080422
NM_080423
PTPN2



protein tyrosine phosphatase, non-receptor type 2



chr19_+_42724431 0.966 NM_133444
ZNF526
zinc finger protein 526
chr7_-_44621819 0.965 NM_182547
TMED4
transmembrane emp24 protein transport domain containing 4
chr19_+_3762650 0.957 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr4_+_6717899 0.940 CNO
cappuccino homolog (mouse)
chr3_-_107809754 0.939 NM_001777
NM_198793
CD47

CD47 molecule

chr12_-_54673879 0.903 CBX5
chromobox homolog 5
chr2_-_33824294 0.885 NM_015475
FAM98A
family with sequence similarity 98, member A
chr2_-_106810756 0.882 UXS1
UDP-glucuronate decarboxylase 1
chr4_+_7045222 0.880 TADA2B
transcriptional adaptor 2B
chr6_-_33679435 0.878 C6orf125
chromosome 6 open reading frame 125
chr19_-_36909463 0.869 NM_133466
ZFP82
zinc finger protein 82 homolog (mouse)
chr8_+_26435590 0.857 DPYSL2
dihydropyrimidinase-like 2
chr16_-_2390737 0.855 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_-_2390711 0.851 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_-_50432679 0.838 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr4_+_668250 0.837 MYL5
myosin, light chain 5, regulatory
chr6_+_31126340 0.829 TCF19
transcription factor 19
chr19_-_50432734 0.828 NM_012346
NM_153718
NM_153719
NM_001193357
NM_172374
NUP62



IL4I1
nucleoporin 62kDa



interleukin 4 induced 1
chr12_+_107349539 0.821 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr6_+_31126114 0.805 NM_001077511
NM_007109
TCF19

transcription factor 19

chrX_-_40506666 0.796 CXorf38
chromosome X open reading frame 38
chr9_+_37079882 0.787 LOC100506710
endogenous Bornavirus-like nucleoprotein 2 pseudogene
chr16_-_2390593 0.779 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr6_-_33679501 0.767 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr12_-_120554557 0.764 RAB35
RAB35, member RAS oncogene family
chr22_+_45559879 0.763 NUP50
nucleoporin 50kDa
chr4_+_668312 0.757 MYL5
myosin, light chain 5, regulatory
chr3_-_122134881 0.751 NM_019069
WDR5B
WD repeat domain 5B
chr3_-_195717100 0.748 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr3_+_195384918 0.742 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr22_-_50963961 0.741 NM_001169111
NM_005138
SCO2

SCO cytochrome oxidase deficient homolog 2 (yeast)

chr9_+_110045516 0.737 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr10_-_38146978 0.736 ZNF248
zinc finger protein 248
chr16_+_31191430 0.735 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chr12_+_107349673 0.734 C12orf23
chromosome 12 open reading frame 23
chr9_+_100174179 0.732 NM_014290
TDRD7
tudor domain containing 7
chr16_+_50099907 0.724 HEATR3
HEAT repeat containing 3
chr12_+_106751859 0.715 NM_001160708
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr19_+_56879687 0.711 ZNF542
zinc finger protein 542
chr20_+_25176333 0.708 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr4_-_2243847 0.708 NM_024511
POLN
HAUS3
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chrX_-_40506800 0.707 NM_144970
CXorf38
chromosome X open reading frame 38
chr3_-_160167525 0.707 TRIM59
tripartite motif containing 59
chr12_+_69753461 0.701 NM_006530
YEATS4
YEATS domain containing 4
chr1_-_3773620 0.695 CEP104
centrosomal protein 104kDa
chr2_-_106810735 0.694 UXS1
UDP-glucuronate decarboxylase 1
chr1_-_231473478 0.693 NM_175876
EXOC8
exocyst complex component 8
chr2_-_118771719 0.691 NM_019044
CCDC93
coiled-coil domain containing 93
chr13_-_44361032 0.689 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr19_-_2783332 0.688 NM_003021
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr4_-_668035 0.683 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr12_+_123718290 0.683 NM_001143905
C12orf65
chromosome 12 open reading frame 65
chr12_-_112123770 0.681 NM_006768
BRAP
BRCA1 associated protein
chrX_-_51239295 0.673 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_2236648 0.665 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr4_+_7045142 0.659 NM_152293
TADA2B
transcriptional adaptor 2B
chr9_-_139981102 0.658 LOC100289341
uncharacterized LOC100289341
chr19_-_2783313 0.657 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr6_-_24667127 0.655 TDP2
tyrosyl-DNA phosphodiesterase 2
chr9_+_114393543 0.646 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr6_+_89855745 0.644 NM_001010853
PM20D2
peptidase M20 domain containing 2
chr9_-_139981268 0.644 LOC100289341
uncharacterized LOC100289341
chr16_-_90038869 0.639 CENPBD1
CENPB DNA-binding domains containing 1
chr2_-_118771571 0.634 CCDC93
coiled-coil domain containing 93
chr20_-_30539853 0.631 NM_030815
PDRG1
p53 and DNA-damage regulated 1
chr7_-_6388408 0.631 NM_001037163
C7orf70
chromosome 7 open reading frame 70
chr20_-_30539725 0.625 PDRG1
p53 and DNA-damage regulated 1
chr10_-_99185695 0.625


chr2_-_106810781 0.624 NM_025076
UXS1
UDP-glucuronate decarboxylase 1
chr19_+_11071583 0.623 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr4_+_6675798 0.622 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr4_+_6675654 0.621 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr20_-_30539803 0.619 PDRG1
p53 and DNA-damage regulated 1
chr19_+_36236460 0.618 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chr19_-_40023449 0.615 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr3_+_49449753 0.615 TCTA
T-cell leukemia translocation altered gene
chr9_+_71394919 0.608 NM_138333
FAM122A
family with sequence similarity 122A
chr4_+_6717841 0.603 NM_018366
CNO
cappuccino homolog (mouse)
chr2_+_26256728 0.595 NM_016131
RAB10
RAB10, member RAS oncogene family
chr7_+_56132002 0.595 SUMF2
sulfatase modifying factor 2
chr2_+_101179395 0.592 NM_024065
PDCL3
phosducin-like 3
chr10_-_124713693 0.583 NM_024942
C10orf88
chromosome 10 open reading frame 88
chr15_+_41952572 0.579 NM_001080541
NM_001164273
MGA

MAX gene associated

chr6_-_24666818 0.576 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chr19_+_49588660 0.572 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr12_-_120554612 0.570 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family

chr2_-_239112331 0.569 ILKAP
integrin-linked kinase-associated serine/threonine phosphatase
chr19_-_2783225 0.569 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr7_-_6746541 0.557 NM_006956
NM_016265
ZNF12

zinc finger protein 12

chr16_-_90039239 0.554 NM_145039
CENPBD1
CENPB DNA-binding domains containing 1
chr1_-_43424324 0.553 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr3_+_25831548 0.550 NM_001145391
NM_017897
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr19_+_11071792 0.549 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr6_-_153304590 0.549 NM_001142522
FBXO5
F-box protein 5
chr19_+_531737 0.549 CDC34
cell division cycle 34 homolog (S. cerevisiae)
chr9_+_71395079 0.548


chr6_-_117923668 0.545 GOPC
golgi-associated PDZ and coiled-coil motif containing
chr6_+_30614815 0.544 NM_001109938
NM_001161376
NM_145029
C6orf136


chromosome 6 open reading frame 136


chr2_-_239112317 0.537 NM_030768
ILKAP
integrin-linked kinase-associated serine/threonine phosphatase
chr2_-_130939146 0.535 NM_001171083
NM_017751
NM_017951
SMPD4


sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)


chr2_-_74734498 0.535 PCGF1
polycomb group ring finger 1
chr10_-_71993070 0.533 NM_021129
PPA1
pyrophosphatase (inorganic) 1
chr19_-_50432952 0.531 NM_016553
NUP62
nucleoporin 62kDa
chr19_-_58662144 0.529 NM_024620
ZNF329
zinc finger protein 329
chr22_+_45559725 0.528 NM_007172
NUP50
nucleoporin 50kDa
chr3_-_14988976 0.528 LOC100505641
uncharacterized LOC100505641
chr9_-_140024159 0.526


chr7_+_100303673 0.525 NM_005837
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr22_+_45559858 0.525 NUP50
nucleoporin 50kDa
chr15_-_65477441 0.523 NM_006660
CLPX
ClpX caseinolytic peptidase X homolog (E. coli)
chr1_+_197871681 0.521 NM_001024594
C1orf53
chromosome 1 open reading frame 53
chr1_+_91966365 0.520 NM_001134419
NM_003503
CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr7_+_5229911 0.513 WIPI2
WD repeat domain, phosphoinositide interacting 2
chr20_-_44563684 0.511 FLJ40606
uncharacterized LOC643549
chr3_+_183903970 0.511 ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr17_-_42580745 0.511 GPATCH8
G patch domain containing 8
chr19_+_531688 0.509 NM_004359
CDC34
cell division cycle 34 homolog (S. cerevisiae)
chr7_+_5013618 0.509 RNF216P1
ring finger protein 216 pseudogene 1
chr19_+_44100543 0.508 NM_024327
ZNF576
zinc finger protein 576
chr3_-_113465101 0.500 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_137089990 0.500 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr3_+_183903862 0.499 NM_018358
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr10_+_15139181 0.498 NM_001097590
NM_006414
NM_183005
RPP38


ribonuclease P/MRP 38kDa subunit


chr7_+_5229920 0.498 WIPI2
WD repeat domain, phosphoinositide interacting 2
chr2_+_132250500 0.497 LOC150776
sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr6_-_135375954 0.497 NM_001145158
NM_001145207
NM_006620
HBS1L


HBS1-like (S. cerevisiae)


chr12_+_106751550 0.496 POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr5_-_162887105 0.496 NM_145266
NUDCD2
NudC domain containing 2
chr6_-_117923681 0.496 GOPC
golgi-associated PDZ and coiled-coil motif containing
chr3_-_160167600 0.492 NM_173084
TRIM59
tripartite motif containing 59
chr17_+_8339135 0.491 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr2_+_122407564 0.490 LOC254128
uncharacterized LOC254128
chr1_-_40349169 0.490 NM_017646
TRIT1
tRNA isopentenyltransferase 1
chr18_-_19180813 0.490 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_-_51239426 0.489 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_42721802 0.488 NM_133328
DEDD2
death effector domain containing 2
chr19_+_14017015 0.487 CC2D1A
coiled-coil and C2 domain containing 1A
chrX_+_51927918 0.486 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chrX_+_84498993 0.482 NM_021998
ZNF711
zinc finger protein 711
chr13_-_52027133 0.482 INTS6
integrator complex subunit 6
chr2_-_239112193 0.482 ILKAP
integrin-linked kinase-associated serine/threonine phosphatase
chr2_+_264843 0.481 NM_001040649
NM_004300
NM_007099
ACP1


acid phosphatase 1, soluble


chr14_+_102430767 0.481 NM_001376
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr5_-_137089754 0.477 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr12_+_106751435 0.475 NM_018082
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr18_+_9475528 0.471 NM_006788
RALBP1
ralA binding protein 1
chr19_-_58609574 0.466 ZSCAN18
zinc finger and SCAN domain containing 18
chr7_+_100027404 0.465 MEPCE
methylphosphate capping enzyme
chr1_+_91966653 0.465 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chrX_-_51812249 0.464 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr5_+_162887516 0.464 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr19_-_2236246 0.462 NM_018049
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr17_+_49337909 0.460 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr17_+_49337892 0.459 NM_016001
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr17_+_49337882 0.459 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr10_-_124639077 0.458 NM_001204364
NM_152644
FAM24B-CUZD1
FAM24B

FAM24B-CUZD1 readthrough
family with sequence similarity 24, member B

chr10_+_15139329 0.457 RPP38
ribonuclease P/MRP 38kDa subunit
chr14_-_50319472 0.455 NEMF
nuclear export mediator factor
chr20_-_54967221 0.454 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr19_-_39340362 0.453 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr6_-_117923451 0.451 GOPC
golgi-associated PDZ and coiled-coil motif containing
chr13_-_52027274 0.451 NM_001039937
NM_001039938
NM_012141
INTS6


integrator complex subunit 6


chr10_+_86088156 0.450 NM_018999
FAM190B
family with sequence similarity 190, member B
chr2_-_17935079 0.449 NM_001142286
NM_024624
SMC6

structural maintenance of chromosomes 6

chr1_+_41445359 0.449 CTPS
CTP synthase
chr16_+_27215295 0.448 NM_001145348
JMJD5
jumonji domain containing 5
chr22_-_28315202 0.446 PITPNB
phosphatidylinositol transfer protein, beta
chr19_+_49588716 0.445 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr1_+_24969766 0.440 SRRM1
serine/arginine repetitive matrix 1
chr22_-_28315214 0.437 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr6_-_42981656 0.436 MEA1
male-enhanced antigen 1
chr3_-_14166292 0.433 CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr3_-_14166370 0.432 NM_001098502
NM_144636
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr16_+_11439279 0.425 NM_152308
RMI2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr1_+_41445402 0.425 CTPS
CTP synthase
chr19_+_49588685 0.424 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr7_+_108210291 0.423 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr7_+_158649200 0.421 NM_018051
WDR60
WD repeat domain 60
chr9_-_77643024 0.420 C9orf41
chromosome 9 open reading frame 41
chr5_-_159827042 0.418 NM_022090
C5orf54
chromosome 5 open reading frame 54
chr19_+_49588399 0.417 NM_003089
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr3_-_196159304 0.416 NM_015562
UBXN7
UBX domain protein 7
chr20_+_61427804 0.416 NM_018270
C20orf20
chromosome 20 open reading frame 20

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.46 1.86e-29 GO:0044260 cellular macromolecule metabolic process
1.32 2.92e-23 GO:0044237 cellular metabolic process
1.36 3.25e-21 GO:0043170 macromolecule metabolic process
1.61 2.02e-20 GO:0090304 nucleic acid metabolic process
1.52 9.66e-20 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 1.98e-15 GO:0006807 nitrogen compound metabolic process
1.42 4.10e-15 GO:0034641 cellular nitrogen compound metabolic process
1.58 4.13e-15 GO:0010467 gene expression
1.62 1.06e-14 GO:0006996 organelle organization
1.23 1.07e-14 GO:0008152 metabolic process
1.25 2.33e-14 GO:0044238 primary metabolic process
2.06 3.89e-14 GO:0051276 chromosome organization
1.57 2.48e-13 GO:0016070 RNA metabolic process
1.41 7.94e-12 GO:0071841 cellular component organization or biogenesis at cellular level
1.92 5.28e-11 GO:0006396 RNA processing
1.38 1.42e-09 GO:0071842 cellular component organization at cellular level
1.39 4.31e-09 GO:0044267 cellular protein metabolic process
1.48 1.44e-08 GO:0034645 cellular macromolecule biosynthetic process
1.47 2.00e-08 GO:0009059 macromolecule biosynthetic process
1.95 3.66e-08 GO:0006325 chromatin organization
1.77 4.04e-08 GO:0022403 cell cycle phase
1.83 4.14e-07 GO:0016071 mRNA metabolic process
1.80 5.14e-07 GO:0000278 mitotic cell cycle
1.78 8.23e-07 GO:0006259 DNA metabolic process
1.91 9.18e-07 GO:0000279 M phase
1.28 1.04e-06 GO:0071840 cellular component organization or biogenesis
1.63 3.22e-06 GO:0022402 cell cycle process
1.80 4.60e-06 GO:0006974 response to DNA damage stimulus
2.05 5.05e-06 GO:0008380 RNA splicing
1.96 8.22e-06 GO:0051301 cell division
1.09 1.04e-05 GO:0009987 cellular process
1.59 1.27e-05 GO:0033554 cellular response to stress
2.25 1.89e-05 GO:0000375 RNA splicing, via transesterification reactions
2.02 1.90e-05 GO:0000087 M phase of mitotic cell cycle
2.59 2.04e-05 GO:0006323 DNA packaging
2.01 2.22e-05 GO:0048285 organelle fission
2.44 2.68e-05 GO:0071103 DNA conformation change
1.94 2.78e-05 GO:0006281 DNA repair
1.52 3.08e-05 GO:0007049 cell cycle
1.31 4.12e-05 GO:0044249 cellular biosynthetic process
1.25 4.46e-05 GO:0016043 cellular component organization
1.86 5.33e-05 GO:0006397 mRNA processing
2.23 5.65e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.23 5.65e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.99 7.72e-05 GO:0000280 nuclear division
1.99 7.72e-05 GO:0007067 mitosis
2.43 1.38e-04 GO:0006333 chromatin assembly or disassembly
2.00 1.62e-04 GO:0034660 ncRNA metabolic process
1.92 2.57e-04 GO:0006412 translation
1.83 3.20e-04 GO:0016568 chromatin modification
1.28 3.74e-04 GO:0009058 biosynthetic process
1.25 5.17e-04 GO:0019538 protein metabolic process
2.56 5.63e-04 GO:0065004 protein-DNA complex assembly
2.68 6.46e-04 GO:0006334 nucleosome assembly
2.62 6.80e-04 GO:0031497 chromatin assembly
1.65 1.07e-03 GO:0044265 cellular macromolecule catabolic process
1.52 1.13e-03 GO:0046907 intracellular transport
1.58 1.91e-03 GO:0009057 macromolecule catabolic process
2.42 2.31e-03 GO:0071824 protein-DNA complex subunit organization
2.50 2.35e-03 GO:0034728 nucleosome organization
1.41 5.22e-03 GO:0008104 protein localization
1.45 8.41e-03 GO:0045184 establishment of protein localization
2.39 9.38e-03 GO:0007059 chromosome segregation
1.82 9.91e-03 GO:0032446 protein modification by small protein conjugation
1.61 1.05e-02 GO:0034621 cellular macromolecular complex subunit organization
1.28 1.48e-02 GO:0043412 macromolecule modification
2.22 1.84e-02 GO:0045333 cellular respiration
1.37 1.98e-02 GO:0044085 cellular component biogenesis
1.82 2.12e-02 GO:0016567 protein ubiquitination
2.41 2.45e-02 GO:0022904 respiratory electron transport chain
1.68 2.58e-02 GO:0034622 cellular macromolecular complex assembly
1.34 2.79e-02 GO:0033036 macromolecule localization
1.94 3.62e-02 GO:0034470 ncRNA processing
1.34 4.06e-02 GO:0051641 cellular localization
1.69 4.54e-02 GO:0070647 protein modification by small protein conjugation or removal
2.58 5.00e-02 GO:0006302 double-strand break repair

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 3.24e-49 GO:0043231 intracellular membrane-bounded organelle
1.32 7.09e-49 GO:0043227 membrane-bounded organelle
1.21 1.71e-44 GO:0044424 intracellular part
1.21 2.70e-44 GO:0005622 intracellular
1.26 4.17e-42 GO:0043226 organelle
1.26 4.63e-42 GO:0043229 intracellular organelle
1.43 1.06e-38 GO:0005634 nucleus
1.64 1.32e-24 GO:0070013 intracellular organelle lumen
1.34 2.10e-24 GO:0044446 intracellular organelle part
1.64 5.32e-24 GO:0044428 nuclear part
1.61 1.55e-23 GO:0031974 membrane-enclosed lumen
1.33 2.69e-23 GO:0044422 organelle part
1.61 5.00e-23 GO:0043233 organelle lumen
1.68 2.27e-22 GO:0031981 nuclear lumen
1.75 3.91e-18 GO:0005654 nucleoplasm
1.35 1.75e-13 GO:0032991 macromolecular complex
1.98 5.38e-11 GO:0030529 ribonucleoprotein complex
1.17 5.78e-11 GO:0005737 cytoplasm
1.91 2.99e-10 GO:0005694 chromosome
1.96 2.28e-09 GO:0044427 chromosomal part
1.19 2.76e-08 GO:0044444 cytoplasmic part
1.71 3.50e-08 GO:0044451 nucleoplasm part
1.47 5.23e-07 GO:0005739 mitochondrion
2.67 2.15e-06 GO:0044455 mitochondrial membrane part
2.11 7.97e-06 GO:0000785 chromatin
1.27 4.10e-05 GO:0043228 non-membrane-bounded organelle
1.27 4.10e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.25 5.46e-05 GO:0043234 protein complex
1.58 9.00e-05 GO:0044429 mitochondrial part
1.04 1.15e-04 GO:0044464 cell part
1.04 1.20e-04 GO:0005623 cell
1.60 1.43e-03 GO:0005730 nucleolus
2.60 2.20e-03 GO:0031461 cullin-RING ubiquitin ligase complex
2.13 3.87e-03 GO:0000151 ubiquitin ligase complex
2.13 3.87e-03 GO:0000793 condensed chromosome
1.26 4.62e-03 GO:0005829 cytosol
1.46 5.70e-03 GO:0031967 organelle envelope
1.45 8.21e-03 GO:0031975 envelope
2.79 1.65e-02 GO:0034708 methyltransferase complex
2.79 1.65e-02 GO:0035097 histone methyltransferase complex
2.25 2.52e-02 GO:0032993 protein-DNA complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 8.44e-22 GO:0003676 nucleic acid binding
1.76 5.18e-11 GO:0003723 RNA binding
1.39 2.41e-09 GO:0003677 DNA binding
1.17 4.66e-09 GO:0005515 protein binding
1.09 9.34e-08 GO:0005488 binding
1.31 1.79e-05 GO:0000166 nucleotide binding
1.14 5.60e-03 GO:0003824 catalytic activity
2.25 6.84e-03 GO:0051082 unfolded protein binding
1.59 7.38e-03 GO:0016874 ligase activity
3.20 8.93e-03 GO:0043021 ribonucleoprotein binding
1.40 3.83e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.39 4.61e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.39 4.89e-02 GO:0016462 pyrophosphatase activity