Motif ID: PATZ1.p2

Z-value: 1.691


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PATZ1chr22_-_317422170.681.9e-04Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_51113069 7.634 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr8_+_1712011 5.255 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr19_+_39897457 4.960 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr19_-_291335 4.594 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr8_-_103666018 4.529 NM_001032282
KLF10
Kruppel-like factor 10
chr1_+_37940129 4.508 ZC3H12A
zinc finger CCCH-type containing 12A
chr8_-_22550708 4.496 NM_004430
EGR3
early growth response 3
chr6_-_84418705 4.086 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr20_-_62680880 4.041 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr1_+_37940180 3.927 ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_37940074 3.905 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr9_+_133971902 3.822 AIF1L
allograft inflammatory factor 1-like
chr14_+_24867926 3.688 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr9_+_133971862 3.478 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr3_-_47620186 3.440 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr19_-_2015628 3.425 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr12_+_123319977 3.291 NM_003959
HIP1R
huntingtin interacting protein 1 related
chr19_-_31840118 3.155 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr9_+_139971938 3.118 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr22_+_19701968 3.103 NM_002688
SEPT5
septin 5
chr14_-_105634708 3.100 JAG2
jagged 2
chr2_-_43453146 3.094 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr1_+_35258598 3.092 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr16_-_30107492 3.066 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr1_+_61547625 3.032 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr17_-_79008372 3.028 FLJ90757
uncharacterized LOC440465
chr14_+_56584854 2.929 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr3_+_20081523 2.905 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr3_+_37903643 2.903 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr6_-_84419018 2.901 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr9_+_139560243 2.864 EGFL7
EGF-like-domain, multiple 7
chr14_-_105635114 2.826 NM_002226
NM_145159
JAG2

jagged 2

chrX_-_119694871 2.748 CUL4B
cullin 4B
chr17_+_81037504 2.746 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr11_-_68518910 2.722 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr19_-_11308184 2.710 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chrX_-_101186976 2.698 NM_001011657
ZMAT1
zinc finger, matrin-type 1
chr2_-_43453724 2.650 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr2_+_112656180 2.641 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr13_-_110438896 2.637 NM_003749
IRS2
insulin receptor substrate 2
chr3_-_39195034 2.606 CSRNP1
cysteine-serine-rich nuclear protein 1
chr3_-_39195101 2.600 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_+_35760002 2.598 USF2
upstream transcription factor 2, c-fos interacting
chr11_-_119234628 2.593 USP2
ubiquitin specific peptidase 2
chr18_+_11981421 2.590 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_-_33647626 2.590 NM_018207
TRIM62
tripartite motif containing 62
chr10_-_75634219 2.583 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr8_-_30891230 2.533 NM_001015508
PURG
purine-rich element binding protein G
chr6_+_11538486 2.527 NM_001100829
TMEM170B
transmembrane protein 170B
chr11_-_130184459 2.496 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr12_-_106532447 2.477 NUAK1
NUAK family, SNF1-like kinase, 1
chr14_-_91526912 2.439 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr7_+_150690838 2.407 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr9_+_139560193 2.405 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr5_-_171881355 2.398 SH3PXD2B
SH3 and PX domains 2B
chr10_-_81205091 2.387 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_+_6271605 2.385 WFS1
Wolfram syndrome 1 (wolframin)
chr9_-_124990949 2.381 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr3_+_32280211 2.373 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr13_-_72440143 2.352 DACH1
dachshund homolog 1 (Drosophila)
chr14_+_56585147 2.326 PELI2
pellino homolog 2 (Drosophila)
chr2_-_43453737 2.322 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr12_+_57916607 2.317 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr1_-_11714396 2.292 FBXO2
F-box protein 2
chrX_-_70473979 2.285 NM_201599
ZMYM3
zinc finger, MYM-type 3
chr8_+_1711869 2.260 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr20_-_25038501 2.224 NM_001252675
NM_001252677
NM_032501
ACSS1


acyl-CoA synthetase short-chain family member 1


chr9_-_123688352 2.213 TRAF1
TNF receptor-associated factor 1
chr13_-_49107185 2.183 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_+_3068442 2.172 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr15_+_63569748 2.161 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr6_-_16761600 2.120 NM_000332
NM_001128164
ATXN1

ataxin 1

chr4_+_55523906 2.112 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr1_-_9970265 2.105 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr13_-_49107357 2.097 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_+_48757292 2.072 NM_001198595
NM_006873
STON1

stonin 1

chr13_-_49107250 2.061 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr18_+_77155714 2.044 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr6_-_99395774 2.039 FBXL4
F-box and leucine-rich repeat protein 4
chr19_+_39833096 2.029 SAMD4B
sterile alpha motif domain containing 4B
chr3_+_39851028 2.025 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_164528586 2.019 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr12_-_46766563 2.018 NM_018976
SLC38A2
solute carrier family 38, member 2
chr17_-_48943672 2.012 NM_001243885
NM_005749
TOB1

transducer of ERBB2, 1

chr20_+_34680569 2.005 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr18_+_11981552 2.003 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr11_+_7535000 1.987 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr22_-_28197469 1.966 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr19_+_35491225 1.962 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr2_+_8822112 1.962 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_11714738 1.952 NM_012168
FBXO2
F-box protein 2
chr18_+_77155943 1.931 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_291168 1.929 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr9_+_139972195 1.928 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_-_51143091 1.927 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr15_-_65067696 1.924 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr19_-_14316980 1.924 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr2_+_219264719 1.915 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr1_+_212458867 1.890 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr3_+_20081853 1.879 KAT2B
K(lysine) acetyltransferase 2B
chr12_-_46766019 1.879 SLC38A2
solute carrier family 38, member 2
chr9_+_115513050 1.879 NM_001012994
SNX30
sorting nexin family member 30
chr11_-_64570621 1.868 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr19_+_42788605 1.867 NM_015125
CIC
capicua homolog (Drosophila)
chr11_-_47207425 1.840 NM_001184975
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr20_+_42543417 1.825 NM_001098797
TOX2
TOX high mobility group box family member 2
chr12_+_57943806 1.823 KIF5A
kinesin family member 5A
chrX_-_70473941 1.809 ZMYM3
zinc finger, MYM-type 3
chr8_-_29120571 1.801 NM_015254
KIF13B
kinesin family member 13B
chr7_+_17338182 1.798 NM_001621
AHR
aryl hydrocarbon receptor
chr2_-_86116016 1.795 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr19_+_2476122 1.784 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr2_+_48757063 1.775 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr8_-_28243589 1.774 ZNF395
zinc finger protein 395
chr22_-_26986065 1.773 TPST2
tyrosylprotein sulfotransferase 2
chr22_-_26986071 1.769 NM_003595
TPST2
tyrosylprotein sulfotransferase 2
chr2_+_112656200 1.765 MERTK
c-mer proto-oncogene tyrosine kinase
chr10_-_33623771 1.765 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr1_+_1981902 1.741 NM_002744
PRKCZ
protein kinase C, zeta
chr20_+_34742656 1.739 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_+_130374466 1.734 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr3_+_32280154 1.730 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr19_+_50094911 1.715 NM_020719
PRR12
proline rich 12
chr6_-_31865455 1.706 NM_006709
NM_025256
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr16_+_29817810 1.706 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr11_+_7535213 1.699 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_11714471 1.698 FBXO2
F-box protein 2
chr12_+_3186520 1.697 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr15_-_69113089 1.682 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_-_126849556 1.677 NM_001083914
CTBP2
C-terminal binding protein 2
chr19_-_36523770 1.677 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr16_-_89787261 1.671 NM_004913
C16orf7
chromosome 16 open reading frame 7
chr19_-_14629160 1.665 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr19_+_48972464 1.661 NM_004228
NM_017457
CYTH2

cytohesin 2

chr7_-_149470294 1.647 NM_207336
ZNF467
zinc finger protein 467
chr6_-_84419108 1.637 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr9_-_77703040 1.626 NM_001127603
NM_017881
C9orf95

chromosome 9 open reading frame 95

chr19_-_42759279 1.625 NM_006494
ERF
Ets2 repressor factor
chr9_+_131314669 1.624 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr8_+_144816287 1.624 LOC100128338
uncharacterized LOC100128338
chr17_-_76356153 1.618 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr2_-_39664430 1.616 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr9_-_123689172 1.615 NM_005658
TRAF1
TNF receptor-associated factor 1
chr7_+_106685007 1.608 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_65886315 1.603 NM_001003679
NM_001003680
NM_002303
NM_001198681
LEPR


LEPROT
leptin receptor


leptin receptor overlapping transcript
chr15_-_69113213 1.591 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_73442468 1.574 ELN
elastin
chr20_+_306205 1.573 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr9_-_139581823 1.572 AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_-_156685621 1.572 LMBR1
limb region 1 homolog (mouse)
chr21_-_10990838 1.568 NM_199259
NM_199260
NM_199261
TPTE


transmembrane phosphatase with tensin homology


chr6_-_99395807 1.560 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chr15_+_89182038 1.549 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_68119350 1.539 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_-_79787784 1.532 PHIP
pleckstrin homology domain interacting protein
chr17_-_62915580 1.532 LRRC37A3
leucine rich repeat containing 37, member A3
chr21_-_44846927 1.529 NM_173354
SIK1
salt-inducible kinase 1
chr9_+_138371627 1.528 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr11_-_65325632 1.522 NM_001130144
NM_001164266
NM_021070
LTBP3


latent transforming growth factor beta binding protein 3


chr20_-_39317875 1.519 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_+_76540374 1.518 NM_001160011
NM_152996
ST6GALNAC3

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

chr9_-_139581868 1.516 AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr3_+_43328001 1.515 NM_001100594
NM_017719
SNRK

SNF related kinase

chr14_+_100438095 1.514 EVL
Enah/Vasp-like
chr22_-_50699938 1.510 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr4_-_102268333 1.506 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr18_-_72920989 1.498


chrX_+_152760346 1.497 NM_001711
BGN
biglycan
chr14_-_77494621 1.495 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr2_+_24299751 1.492 LOC375190
UPF0638 protein B
chr17_-_76124767 1.486 TMC6
transmembrane channel-like 6
chrX_+_152760452 1.482 BGN
biglycan
chr13_-_111567415 1.480 NM_017664
ANKRD10
ankyrin repeat domain 10
chr9_-_84304378 1.475 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr10_-_25241504 1.473 NM_020200
PRTFDC1
phosphoribosyl transferase domain containing 1
chr12_+_9067130 1.468 NM_004426
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_+_222791151 1.465 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr1_-_11866079 1.463 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr8_-_9008138 1.462 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr9_+_127020462 1.457 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr2_-_240322620 1.455 NM_006037
HDAC4
histone deacetylase 4
chr1_-_3528058 1.453 NM_001409
MEGF6
multiple EGF-like-domains 6
chr17_-_47841468 1.452 FAM117A
family with sequence similarity 117, member A
chr12_-_57824787 1.450 R3HDM2
R3H domain containing 2
chr19_+_17581276 1.449 NM_198580
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr10_-_126849010 1.442 CTBP2
C-terminal binding protein 2
chr19_-_11373117 1.441 NM_020812
DOCK6
dedicator of cytokinesis 6
chr17_-_47841517 1.432 NM_030802
FAM117A
family with sequence similarity 117, member A
chr13_-_72440557 1.427 DACH1
dachshund homolog 1 (Drosophila)
chr17_-_76921453 1.424 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr17_+_38278216 1.421 MSL1
male-specific lethal 1 homolog (Drosophila)
chr7_-_143599163 1.418 NM_014719
NM_001206938
FAM115A

family with sequence similarity 115, member A

chr16_+_68119211 1.413 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr8_-_103667882 1.411 NM_005655
KLF10
Kruppel-like factor 10
chr16_-_90085786 1.411 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr19_-_36523540 1.404 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr14_-_95786095 1.404 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr2_-_99347430 1.399 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_26856252 1.392 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chrX_-_119694492 1.391 CUL4B
cullin 4B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 1.98e-26 GO:0009987 cellular process
1.12 1.94e-15 GO:0044237 cellular metabolic process
1.10 2.48e-14 GO:0065007 biological regulation
1.15 3.61e-14 GO:0044260 cellular macromolecule metabolic process
1.10 2.37e-13 GO:0050789 regulation of biological process
1.11 7.68e-13 GO:0050794 regulation of cellular process
1.11 2.51e-12 GO:0044238 primary metabolic process
1.10 5.02e-12 GO:0008152 metabolic process
1.23 5.42e-11 GO:0006464 protein modification process
1.13 7.52e-11 GO:0043170 macromolecule metabolic process
1.22 4.46e-10 GO:0043412 macromolecule modification
1.17 1.44e-08 GO:0044267 cellular protein metabolic process
1.18 4.66e-08 GO:0048519 negative regulation of biological process
1.18 7.37e-08 GO:0048523 negative regulation of cellular process
1.16 1.05e-07 GO:0048518 positive regulation of biological process
1.17 1.33e-07 GO:0048522 positive regulation of cellular process
1.28 3.04e-06 GO:0051128 regulation of cellular component organization
1.20 5.09e-06 GO:0007399 nervous system development
1.24 3.06e-05 GO:0009892 negative regulation of metabolic process
1.25 3.24e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.19 6.81e-05 GO:0009966 regulation of signal transduction
1.13 7.48e-05 GO:0019538 protein metabolic process
1.23 1.00e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.36 1.20e-04 GO:0040008 regulation of growth
1.10 1.87e-04 GO:0051716 cellular response to stimulus
1.29 1.92e-04 GO:0010629 negative regulation of gene expression
1.12 1.96e-04 GO:0060255 regulation of macromolecule metabolic process
1.38 2.00e-04 GO:0016568 chromatin modification
1.11 2.62e-04 GO:0016043 cellular component organization
1.17 3.06e-04 GO:0023051 regulation of signaling
1.11 4.12e-04 GO:0031323 regulation of cellular metabolic process
1.10 4.86e-04 GO:0019222 regulation of metabolic process
1.37 5.07e-04 GO:0018193 peptidyl-amino acid modification
1.10 8.02e-04 GO:0023052 signaling
1.34 1.08e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.26 1.22e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.22 1.23e-03 GO:0031324 negative regulation of cellular metabolic process
1.11 1.30e-03 GO:0006807 nitrogen compound metabolic process
1.10 1.82e-03 GO:0080090 regulation of primary metabolic process
1.11 2.21e-03 GO:0007165 signal transduction
1.10 2.51e-03 GO:0071840 cellular component organization or biogenesis
1.25 2.54e-03 GO:0009890 negative regulation of biosynthetic process
1.10 2.74e-03 GO:0007275 multicellular organismal development
1.28 3.76e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.10 4.17e-03 GO:0051179 localization
1.18 4.17e-03 GO:0009893 positive regulation of metabolic process
1.18 4.48e-03 GO:0031325 positive regulation of cellular metabolic process
1.18 6.63e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.19 7.13e-03 GO:0007049 cell cycle
1.20 8.27e-03 GO:0042127 regulation of cell proliferation
1.25 8.64e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.11 8.67e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 9.18e-03 GO:0033036 macromolecule localization
1.09 9.27e-03 GO:0032502 developmental process
1.24 9.84e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.19 1.10e-02 GO:0006793 phosphorus metabolic process
1.19 1.10e-02 GO:0006796 phosphate metabolic process
1.26 1.13e-02 GO:0051253 negative regulation of RNA metabolic process
1.40 1.30e-02 GO:0051129 negative regulation of cellular component organization
1.25 1.41e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.10 1.67e-02 GO:0034641 cellular nitrogen compound metabolic process
1.11 2.00e-02 GO:0048731 system development
1.24 2.18e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.18 2.22e-02 GO:0010646 regulation of cell communication
1.43 3.21e-02 GO:0016569 covalent chromatin modification
1.23 3.32e-02 GO:0051726 regulation of cell cycle
1.13 3.33e-02 GO:0048583 regulation of response to stimulus
1.12 3.41e-02 GO:0090304 nucleic acid metabolic process
1.11 3.41e-02 GO:0009889 regulation of biosynthetic process
1.30 4.13e-02 GO:0044419 interspecies interaction between organisms
1.43 4.83e-02 GO:0016570 histone modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 3.33e-35 GO:0005622 intracellular
1.09 2.09e-33 GO:0044424 intracellular part
1.11 2.57e-25 GO:0043227 membrane-bounded organelle
1.11 6.05e-25 GO:0043231 intracellular membrane-bounded organelle
1.11 4.75e-24 GO:0005737 cytoplasm
1.10 1.18e-23 GO:0043226 organelle
1.10 1.54e-23 GO:0043229 intracellular organelle
1.13 1.13e-16 GO:0044444 cytoplasmic part
1.12 5.03e-14 GO:0005634 nucleus
1.19 4.41e-10 GO:0044428 nuclear part
1.20 5.34e-10 GO:0005829 cytosol
1.21 1.04e-09 GO:0031981 nuclear lumen
1.10 6.04e-09 GO:0044422 organelle part
1.10 9.05e-09 GO:0044446 intracellular organelle part
1.17 6.97e-08 GO:0070013 intracellular organelle lumen
1.16 1.56e-07 GO:0043233 organelle lumen
1.20 4.41e-07 GO:0012505 endomembrane system
1.15 1.10e-06 GO:0031974 membrane-enclosed lumen
1.20 7.04e-06 GO:0005654 nucleoplasm
1.55 1.87e-05 GO:0070161 anchoring junction
1.58 1.87e-05 GO:0005912 adherens junction
1.02 2.22e-05 GO:0005623 cell
1.02 2.61e-05 GO:0044464 cell part
1.20 4.70e-04 GO:0005794 Golgi apparatus
1.62 6.51e-04 GO:0005925 focal adhesion
1.23 1.58e-03 GO:0005789 endoplasmic reticulum membrane
1.13 1.67e-03 GO:0031090 organelle membrane
1.18 2.48e-03 GO:0005783 endoplasmic reticulum
1.57 2.89e-03 GO:0005924 cell-substrate adherens junction
1.27 3.72e-03 GO:0000139 Golgi membrane
1.21 5.18e-03 GO:0044432 endoplasmic reticulum part
1.24 5.42e-03 GO:0044431 Golgi apparatus part
1.22 5.95e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.22 6.84e-03 GO:0015630 microtubule cytoskeleton
1.54 7.06e-03 GO:0030055 cell-substrate junction
1.10 7.92e-03 GO:0043234 protein complex
1.35 1.66e-02 GO:0016323 basolateral plasma membrane
1.59 1.81e-02 GO:0000790 nuclear chromatin
1.80 2.21e-02 GO:0000792 heterochromatin
1.27 4.22e-02 GO:0048471 perinuclear region of cytoplasm
1.21 4.46e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 2.34e-31 GO:0005515 protein binding
1.08 1.19e-26 GO:0005488 binding
1.19 1.94e-07 GO:0016740 transferase activity
1.09 1.74e-06 GO:0003824 catalytic activity
1.25 3.48e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.36 5.71e-06 GO:0019904 protein domain specific binding
1.15 1.86e-05 GO:0000166 nucleotide binding
1.25 3.88e-05 GO:0016301 kinase activity
1.26 4.98e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.50 1.16e-04 GO:0003682 chromatin binding
1.17 2.28e-04 GO:0030554 adenyl nucleotide binding
1.16 3.66e-04 GO:0032559 adenyl ribonucleotide binding
1.23 1.57e-03 GO:0019899 enzyme binding
1.36 2.03e-03 GO:0008134 transcription factor binding
1.14 2.27e-03 GO:0017076 purine nucleotide binding
1.14 2.79e-03 GO:0032553 ribonucleotide binding
1.14 2.79e-03 GO:0032555 purine ribonucleotide binding
1.24 3.02e-03 GO:0004672 protein kinase activity
1.15 3.21e-03 GO:0005524 ATP binding
1.46 5.48e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.10 5.74e-03 GO:0003676 nucleic acid binding
1.09 6.80e-03 GO:0043167 ion binding
1.08 7.25e-03 GO:0043169 cation binding
1.09 7.80e-03 GO:0046872 metal ion binding
1.13 1.16e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.26 2.30e-02 GO:0004674 protein serine/threonine kinase activity
1.25 2.32e-02 GO:0030695 GTPase regulator activity
1.28 2.38e-02 GO:0000988 protein binding transcription factor activity
1.28 2.38e-02 GO:0000989 transcription factor binding transcription factor activity
1.17 2.93e-02 GO:0001071 nucleic acid binding transcription factor activity
1.17 2.93e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.44 3.01e-02 GO:0003714 transcription corepressor activity
1.28 3.08e-02 GO:0003712 transcription cofactor activity
1.17 3.63e-02 GO:0030528 transcription regulator activity
1.30 3.75e-02 GO:0016564 transcription repressor activity